Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= tesS0640
(648 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase (oxa... 119 8e-27
U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-depende... 119 8e-27
L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzy... 119 8e-27
BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 119 8e-27
AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 119 8e-27
AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1, NADP(+)... 119 8e-27
AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 119 8e-27
AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme ... 119 8e-27
X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase (oxa... 118 2e-26
BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3, NADP(+)... 118 2e-26
AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial NADP(+)-d... 118 2e-26
AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens ... 118 2e-26
M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+ -de... 98 2e-20
BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein. 98 2e-20
>X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 572
Score = 119 bits (287), Expect = 8e-27
Identities = 60/107 (56%), Positives = 73/107 (68%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQDR EKLF+ +L DI KFMPIVYTPTVG ACQ++ LV+R+PRGL+ITIHD+GHI +
Sbjct: 77 DLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASV 136
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
L + + GERILG G L G GIPVG+ LYT G
Sbjct: 137 LNAWPEDVIKAIVVTDGERILGLGD-LGCNGMGIPVGKLA-LYTACG 181
>U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-dependent
malic enzyme protein.
Length = 565
Score = 119 bits (287), Expect = 8e-27
Identities = 60/107 (56%), Positives = 73/107 (68%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQDR EKLF+ +L DI KFMPIVYTPTVG ACQ++ LV+R+PRGL+ITIHD+GHI +
Sbjct: 70 DLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASV 129
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
L + + GERILG G L G GIPVG+ LYT G
Sbjct: 130 LNAWPEDVIKAIVVTDGERILGLGD-LGCNGMGIPVGKLA-LYTACG 174
>L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzyme
protein.
Length = 572
Score = 119 bits (287), Expect = 8e-27
Identities = 60/107 (56%), Positives = 73/107 (68%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQDR EKLF+ +L DI KFMPIVYTPTVG ACQ++ LV+R+PRGL+ITIHD+GHI +
Sbjct: 77 DLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASV 136
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
L + + GERILG G L G GIPVG+ LYT G
Sbjct: 137 LNAWPEDVIKAIVVTDGERILGLGD-LGCNGMGIPVGKLA-LYTACG 181
>BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 119 bits (287), Expect = 8e-27
Identities = 60/107 (56%), Positives = 73/107 (68%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQDR EKLF+ +L DI KFMPIVYTPTVG ACQ++ LV+R+PRGL+ITIHD+GHI +
Sbjct: 77 DLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASV 136
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
L + + GERILG G L G GIPVG+ LYT G
Sbjct: 137 LNAWPEDVIKAIVVTDGERILGLGD-LGCNGMGIPVGKLA-LYTACG 181
>AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 119 bits (287), Expect = 8e-27
Identities = 60/107 (56%), Positives = 73/107 (68%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQDR EKLF+ +L DI KFMPIVYTPTVG ACQ++ LV+R+PRGL+ITIHD+GHI +
Sbjct: 77 DLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASV 136
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
L + + GERILG G L G GIPVG+ LYT G
Sbjct: 137 LNAWPEDVIKAIVVTDGERILGLGD-LGCNGMGIPVGKLA-LYTACG 181
>AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 119 bits (287), Expect = 8e-27
Identities = 60/107 (56%), Positives = 73/107 (68%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQDR EKLF+ +L DI KFMPIVYTPTVG ACQ++ LV+R+PRGL+ITIHD+GHI +
Sbjct: 77 DLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASV 136
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
L + + GERILG G L G GIPVG+ LYT G
Sbjct: 137 LNAWPEDVIKAIVVTDGERILGLGD-LGCNGMGIPVGKLA-LYTACG 181
>AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 119 bits (287), Expect = 8e-27
Identities = 60/107 (56%), Positives = 73/107 (68%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQDR EKLF+ +L DI KFMPIVYTPTVG ACQ++ LV+R+PRGL+ITIHD+GHI +
Sbjct: 77 DLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASV 136
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
L + + GERILG G L G GIPVG+ LYT G
Sbjct: 137 LNAWPEDVIKAIVVTDGERILGLGD-LGCNGMGIPVGKLA-LYTACG 181
>AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme 1
variant protein.
Length = 572
Score = 119 bits (287), Expect = 8e-27
Identities = 60/107 (56%), Positives = 73/107 (68%)
Frame = +1
Query: 322 ELQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDI 501
+LQDR EKLF+ +L DI KFMPIVYTPTVG ACQ++ LV+R+PRGL+ITIHD+GHI +
Sbjct: 77 DLQDRNEKLFYRVLTSDIEKFMPIVYTPTVGLACQQYSLVFRKPRGLFITIHDRGHIASV 136
Query: 502 LKTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
L + + GERILG G L G GIPVG+ LYT G
Sbjct: 137 LNAWPEDVIKAIVVTDGERILGLGD-LGCNGMGIPVGKLA-LYTACG 181
>X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 604
Score = 118 bits (283), Expect = 2e-26
Identities = 60/106 (56%), Positives = 71/106 (66%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
LQDR EKLF+ +L D+ KFMPIVYTPTVG ACQ +GL +RRPRGL+ITIHDKGH+ +L
Sbjct: 113 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 172
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + GERILG G L G GIPVG+ LYT G
Sbjct: 173 NSWPEDNIKAVVVTDGERILGLGD-LGCYGMGIPVGKLA-LYTACG 216
Score = 34.3 bits (75), Expect = 0.38
Identities = 15/25 (60%), Positives = 18/25 (72%)
Frame = +3
Query: 123 PNMLRGIDHIKDPRLNKGLAFTLEE 197
P RG D ++P LNKG+AFTLEE
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEE 69
>BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3,
NADP(+)-dependent, mitochondrial protein.
Length = 604
Score = 118 bits (283), Expect = 2e-26
Identities = 60/106 (56%), Positives = 71/106 (66%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
LQDR EKLF+ +L D+ KFMPIVYTPTVG ACQ +GL +RRPRGL+ITIHDKGH+ +L
Sbjct: 113 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 172
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + GERILG G L G GIPVG+ LYT G
Sbjct: 173 NSWPEDNIKAVVVTDGERILGLGD-LGCYGMGIPVGKLA-LYTACG 216
Score = 34.3 bits (75), Expect = 0.38
Identities = 15/25 (60%), Positives = 18/25 (72%)
Frame = +3
Query: 123 PNMLRGIDHIKDPRLNKGLAFTLEE 197
P RG D ++P LNKG+AFTLEE
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEE 69
>AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial
NADP(+)-dependent malic enzyme 3 protein.
Length = 259
Score = 118 bits (283), Expect = 2e-26
Identities = 60/106 (56%), Positives = 71/106 (66%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
LQDR EKLF+ +L D+ KFMPIVYTPTVG ACQ +GL +RRPRGL+ITIHDKGH+ +L
Sbjct: 51 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 110
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + GERILG G L G GIPVG+ LYT G
Sbjct: 111 NSWPEDNIKAVVVTDGERILGLGD-LGCYGMGIPVGKLA-LYTACG 154
>AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens
cDNA FLJ34862 fis, clone NT2NE2013547, highly similar to
NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR (EC
1.1.1.40). ).
Length = 252
Score = 118 bits (283), Expect = 2e-26
Identities = 60/106 (56%), Positives = 71/106 (66%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
LQDR EKLF+ +L D+ KFMPIVYTPTVG ACQ +GL +RRPRGL+ITIHDKGH+ +L
Sbjct: 51 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATML 110
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYTGAG 642
+ + GERILG G L G GIPVG+ LYT G
Sbjct: 111 NSWPEDNIKAVVVTDGERILGLGD-LGCYGMGIPVGKLA-LYTACG 154
>M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+
-dependent malic enzyme protein.
Length = 584
Score = 98.3 bits (234), Expect = 2e-20
Identities = 50/103 (48%), Positives = 67/103 (65%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
+Q+R EKLF+ +L DI MPIVYTPTVG AC ++G ++RRP+GL+I+I D+GH+ I+
Sbjct: 88 IQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIV 147
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYT 633
+ GERILG G L + G GIPVG+ LYT
Sbjct: 148 DNWPENHVKAVVVTDGERILGLGD-LGVYGMGIPVGKL-CLYT 188
>BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein.
Length = 479
Score = 98.3 bits (234), Expect = 2e-20
Identities = 50/103 (48%), Positives = 67/103 (65%)
Frame = +1
Query: 325 LQDRXEKLFFSLLDCDIXKFMPIVYTPTVGXACQKFGLVYRRPRGLYITIHDKGHIFDIL 504
+Q+R EKLF+ +L DI MPIVYTPTVG AC ++G ++RRP+GL+I+I D+GH+ I+
Sbjct: 88 IQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHVRSIV 147
Query: 505 KTGQSMLSAQ*FLQTGERILGXGRFLALMGWGIPVGQTGPLYT 633
+ GERILG G L + G GIPVG+ LYT
Sbjct: 148 DNWPENHVKAVVVTDGERILGLGD-LGVYGMGIPVGKL-CLYT 188
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 90,202,345
Number of Sequences: 237096
Number of extensions: 1797703
Number of successful extensions: 3780
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 3493
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3760
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7197658880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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