Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= tesS0608
(578 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase (oxa... 101 2e-21
U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-depende... 101 2e-21
L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzy... 101 2e-21
BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 101 2e-21
AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 101 2e-21
AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1, NADP(+)... 101 2e-21
AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1, NADP(+)... 101 2e-21
AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme ... 101 2e-21
X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase (oxa... 98 2e-20
BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3, NADP(+)... 98 2e-20
AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial NADP(+)-d... 98 2e-20
AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens ... 98 2e-20
M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+ -de... 82 2e-15
BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein. 82 2e-15
>X77244-1|CAA54460.1| 572|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 572
Score = 101 bits (241), Expect = 2e-21
Identities = 48/88 (54%), Positives = 60/88 (68%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXXI 518
VGLACQ++ LV+R+PRGL+ITIHD+ I
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHI 133
>U43944-1|AAC50613.1| 565|Homo sapiens cytosolic NADP(+)-dependent
malic enzyme protein.
Length = 565
Score = 101 bits (241), Expect = 2e-21
Identities = 48/88 (54%), Positives = 60/88 (68%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 39 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 98
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXXI 518
VGLACQ++ LV+R+PRGL+ITIHD+ I
Sbjct: 99 VGLACQQYSLVFRKPRGLFITIHDRGHI 126
>L34035-1|AAB01380.1| 572|Homo sapiens NADP-dependent malic enzyme
protein.
Length = 572
Score = 101 bits (241), Expect = 2e-21
Identities = 48/88 (54%), Positives = 60/88 (68%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXXI 518
VGLACQ++ LV+R+PRGL+ITIHD+ I
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHI 133
>BC025246-1|AAH25246.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 101 bits (241), Expect = 2e-21
Identities = 48/88 (54%), Positives = 60/88 (68%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXXI 518
VGLACQ++ LV+R+PRGL+ITIHD+ I
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHI 133
>AL391416-2|CAH73129.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 101 bits (241), Expect = 2e-21
Identities = 48/88 (54%), Positives = 60/88 (68%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXXI 518
VGLACQ++ LV+R+PRGL+ITIHD+ I
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHI 133
>AL136970-1|CAC19505.2| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 101 bits (241), Expect = 2e-21
Identities = 48/88 (54%), Positives = 60/88 (68%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXXI 518
VGLACQ++ LV+R+PRGL+ITIHD+ I
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHI 133
>AL049699-1|CAI22634.1| 572|Homo sapiens malic enzyme 1,
NADP(+)-dependent, cytosolic protein.
Length = 572
Score = 101 bits (241), Expect = 2e-21
Identities = 48/88 (54%), Positives = 60/88 (68%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXXI 518
VGLACQ++ LV+R+PRGL+ITIHD+ I
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHI 133
>AK223417-1|BAD97137.1| 572|Homo sapiens cytosolic malic enzyme 1
variant protein.
Length = 572
Score = 101 bits (241), Expect = 2e-21
Identities = 48/88 (54%), Positives = 60/88 (68%)
Frame = +3
Query: 255 PKFKTQEEQLEFCQISFXXXXXXXXXXXXXTELQDRNEKLFFSLLDCDIEKFMPIVYTPT 434
P F +QE Q+ +F +LQDRNEKLF+ +L DIEKFMPIVYTPT
Sbjct: 46 PSFNSQEIQVLRVVKNFEHLNSDFDRYLLLMDLQDRNEKLFYRVLTSDIEKFMPIVYTPT 105
Query: 435 VGLACQKFGLVYRRPRGLYITIHDKXXI 518
VGLACQ++ LV+R+PRGL+ITIHD+ I
Sbjct: 106 VGLACQQYSLVFRKPRGLFITIHDRGHI 133
>X79440-1|CAA55956.1| 604|Homo sapiens malate dehydrogenase
(oxaloacetate decarboxylating) (NADP+) protein.
Length = 604
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/53 (79%), Positives = 48/53 (90%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 509
LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 113 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 165
Score = 34.3 bits (75), Expect = 0.32
Identities = 15/25 (60%), Positives = 18/25 (72%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEE 223
P RG D ++P LNKG+AFTLEE
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEE 69
>BC022472-1|AAH22472.1| 604|Homo sapiens malic enzyme 3,
NADP(+)-dependent, mitochondrial protein.
Length = 604
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/53 (79%), Positives = 48/53 (90%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 509
LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 113 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 165
Score = 34.3 bits (75), Expect = 0.32
Identities = 15/25 (60%), Positives = 18/25 (72%)
Frame = +2
Query: 149 PNMLRGIDHIKDPRLNKGLAFTLEE 223
P RG D ++P LNKG+AFTLEE
Sbjct: 45 PLKKRGYDVTRNPHLNKGMAFTLEE 69
>AY424278-1|AAR04784.1| 259|Homo sapiens mitochondrial
NADP(+)-dependent malic enzyme 3 protein.
Length = 259
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/53 (79%), Positives = 48/53 (90%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 509
LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 51 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 103
>AK092181-1|BAC03822.1| 252|Homo sapiens protein ( Homo sapiens
cDNA FLJ34862 fis, clone NT2NE2013547, highly similar to
NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR (EC
1.1.1.40). ).
Length = 252
Score = 98.3 bits (234), Expect = 2e-20
Identities = 42/53 (79%), Positives = 48/53 (90%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDK 509
LQDRNEKLF+ +L D+EKFMPIVYTPTVGLACQ +GL +RRPRGL+ITIHDK
Sbjct: 51 LQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDK 103
>M55905-1|AAA36197.1| 584|Homo sapiens mitochondrial NAD(P)+
-dependent malic enzyme protein.
Length = 584
Score = 81.8 bits (193), Expect = 2e-15
Identities = 33/56 (58%), Positives = 46/56 (82%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXXI 518
+Q+RNEKLF+ +L DIE MPIVYTPTVGLAC ++G ++RRP+GL+I+I D+ +
Sbjct: 88 IQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHV 143
Score = 30.3 bits (65), Expect = 5.1
Identities = 11/18 (61%), Positives = 15/18 (83%)
Frame = +1
Query: 523 ILKNWPEHAVRAIVFTDG 576
I+ NWPE+ V+A+V TDG
Sbjct: 146 IVDNWPENHVKAVVVTDG 163
>BC000147-1|AAH00147.1| 479|Homo sapiens ME2 protein protein.
Length = 479
Score = 81.8 bits (193), Expect = 2e-15
Identities = 33/56 (58%), Positives = 46/56 (82%)
Frame = +3
Query: 351 LQDRNEKLFFSLLDCDIEKFMPIVYTPTVGLACQKFGLVYRRPRGLYITIHDKXXI 518
+Q+RNEKLF+ +L DIE MPIVYTPTVGLAC ++G ++RRP+GL+I+I D+ +
Sbjct: 88 IQERNEKLFYRILQDDIESLMPIVYTPTVGLACSQYGHIFRRPKGLFISISDRGHV 143
Score = 30.3 bits (65), Expect = 5.1
Identities = 11/18 (61%), Positives = 15/18 (83%)
Frame = +1
Query: 523 ILKNWPEHAVRAIVFTDG 576
I+ NWPE+ V+A+V TDG
Sbjct: 146 IVDNWPENHVKAVVVTDG 163
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,771,249
Number of Sequences: 237096
Number of extensions: 1356715
Number of successful extensions: 5892
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5840
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5892
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5985693436
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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