Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= tesS0425
(698 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 98 3e-20
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 98 3e-20
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 98 3e-20
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 98 3e-20
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 98 3e-20
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 98 3e-20
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 98 3e-20
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 92 2e-18
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 92 2e-18
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 92 2e-18
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 92 2e-18
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 90 6e-18
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 90 6e-18
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 81 4e-15
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 81 4e-15
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 81 4e-15
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 81 4e-15
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 81 4e-15
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 81 4e-15
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 81 4e-15
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 81 4e-15
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 81 4e-15
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 77 8e-14
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 77 8e-14
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 77 8e-14
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 77 8e-14
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 77 8e-14
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 77 8e-14
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 77 8e-14
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 76 1e-13
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 76 1e-13
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 76 1e-13
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 76 1e-13
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 76 1e-13
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 76 1e-13
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 74 6e-13
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 74 6e-13
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 72 2e-12
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 6e-09
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 38 0.046
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 35 0.24
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 35 0.24
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 35 0.24
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 35 0.24
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 35 0.24
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 35 0.24
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 35 0.24
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 35 0.24
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 35 0.24
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 35 0.24
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 35 0.24
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.32
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.32
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.32
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 35 0.32
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 35 0.32
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 35 0.32
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 35 0.32
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 35 0.32
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 35 0.32
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 35 0.32
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 35 0.32
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 35 0.32
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 35 0.32
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 35 0.32
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 35 0.32
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 32 1.7
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 5.2
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 30 6.9
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 30 6.9
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 30 6.9
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 30 6.9
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 30 6.9
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 30 6.9
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 30 6.9
AL121914-8|CAI19327.1| 106|Homo sapiens aurora kinase A protein. 30 9.1
AL121914-7|CAM45839.1| 189|Homo sapiens aurora kinase A protein. 30 9.1
AL121914-6|CAI19326.2| 147|Homo sapiens aurora kinase A protein. 30 9.1
AL121914-5|CAI19324.1| 271|Homo sapiens aurora kinase A protein. 30 9.1
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 30 9.1
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 30 9.1
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 30 9.1
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 97.9 bits (233), Expect = 3e-20
Identities = 51/97 (52%), Positives = 60/97 (61%), Gaps = 11/97 (11%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYG 398
+R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 22 VRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYG 81
Query: 399 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 509
I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 82 EIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +2
Query: 506 FLHNKYDSRKSKTYVANGHPVSRYSTGSGSL 598
++H+KY+S KS TYV NG + GSGSL
Sbjct: 118 WIHHKYNSDKSSTYVKNGTSFDIH-YGSGSL 147
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 97.9 bits (233), Expect = 3e-20
Identities = 51/97 (52%), Positives = 60/97 (61%), Gaps = 11/97 (11%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYG 398
+R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 22 VRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYG 81
Query: 399 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 509
I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 82 EIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +2
Query: 506 FLHNKYDSRKSKTYVANGHPVSRYSTGSGSL 598
++H+KY+S KS TYV NG + GSGSL
Sbjct: 118 WIHHKYNSDKSSTYVKNGTSFDIH-YGSGSL 147
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 97.9 bits (233), Expect = 3e-20
Identities = 51/97 (52%), Positives = 60/97 (61%), Gaps = 11/97 (11%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYG 398
+R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 22 VRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYG 81
Query: 399 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 509
I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 82 EIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +2
Query: 506 FLHNKYDSRKSKTYVANGHPVSRYSTGSGSL 598
++H+KY+S KS TYV NG + GSGSL
Sbjct: 118 WIHHKYNSDKSSTYVKNGTSFDIH-YGSGSL 147
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 97.9 bits (233), Expect = 3e-20
Identities = 51/97 (52%), Positives = 60/97 (61%), Gaps = 11/97 (11%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYG 398
+R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 22 VRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYG 81
Query: 399 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 509
I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 82 EIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +2
Query: 506 FLHNKYDSRKSKTYVANGHPVSRYSTGSGSL 598
++H+KY+S KS TYV NG + GSGSL
Sbjct: 118 WIHHKYNSDKSSTYVKNGTSFDIH-YGSGSL 147
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 97.9 bits (233), Expect = 3e-20
Identities = 51/97 (52%), Positives = 60/97 (61%), Gaps = 11/97 (11%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYG 398
+R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 22 VRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYG 81
Query: 399 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 509
I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 82 EIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +2
Query: 506 FLHNKYDSRKSKTYVANGHPVSRYSTGSGSL 598
++H+KY+S KS TYV NG + GSGSL
Sbjct: 118 WIHHKYNSDKSSTYVKNGTSFDIH-YGSGSL 147
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 97.9 bits (233), Expect = 3e-20
Identities = 51/97 (52%), Positives = 60/97 (61%), Gaps = 11/97 (11%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYG 398
+R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 22 VRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYG 81
Query: 399 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 509
I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 82 EIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +2
Query: 506 FLHNKYDSRKSKTYVANGHPVSRYSTGSGSL 598
++H+KY+S KS TYV NG + GSGSL
Sbjct: 118 WIHHKYNSDKSSTYVKNGTSFDIH-YGSGSL 147
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 97.9 bits (233), Expect = 3e-20
Identities = 51/97 (52%), Positives = 60/97 (61%), Gaps = 11/97 (11%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEPLSNYLDAQYYG 398
+R+PLH+ + R EVG +E L K V+ GP PE L NY+DAQYYG
Sbjct: 22 VRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEVLKNYMDAQYYG 81
Query: 399 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACF 509
I IGTPPQ F VVFDTGSSNLWVPS C +IAC+
Sbjct: 82 EIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACW 118
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/31 (51%), Positives = 21/31 (67%)
Frame = +2
Query: 506 FLHNKYDSRKSKTYVANGHPVSRYSTGSGSL 598
++H+KY+S KS TYV NG + GSGSL
Sbjct: 118 WIHHKYNSDKSSTYVKNGTSFDIH-YGSGSL 147
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 92.3 bits (219), Expect = 2e-18
Identities = 47/111 (42%), Positives = 63/111 (56%), Gaps = 5/111 (4%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIGT 416
IR+PLHR++ R + + EL +L G P PLSNY D QY+G I +GT
Sbjct: 27 IRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGT 86
Query: 417 PPQSFKVVFDTGSSNLWVPSKKCHYTNIACFCXXXXXXXXXXXXXXMGTQF 569
PPQ+F V FDTGSSNLWVPS++CH+ ++ C+ GT+F
Sbjct: 87 PPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKF 137
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 91.9 bits (218), Expect = 2e-18
Identities = 47/111 (42%), Positives = 63/111 (56%), Gaps = 5/111 (4%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIGT 416
IR+PLHR++ R + + EL +L G P PLSNY D QY+G I +GT
Sbjct: 27 IRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGT 86
Query: 417 PPQSFKVVFDTGSSNLWVPSKKCHYTNIACFCXXXXXXXXXXXXXXMGTQF 569
PPQ+F V FDTGSSNLWVPS++CH+ ++ C+ GT+F
Sbjct: 87 PPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKF 137
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 91.9 bits (218), Expect = 2e-18
Identities = 47/111 (42%), Positives = 63/111 (56%), Gaps = 5/111 (4%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIGT 416
IR+PLHR++ R + + EL +L G P PLSNY D QY+G I +GT
Sbjct: 27 IRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGT 86
Query: 417 PPQSFKVVFDTGSSNLWVPSKKCHYTNIACFCXXXXXXXXXXXXXXMGTQF 569
PPQ+F V FDTGSSNLWVPS++CH+ ++ C+ GT+F
Sbjct: 87 PPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKF 137
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 91.9 bits (218), Expect = 2e-18
Identities = 47/111 (42%), Positives = 63/111 (56%), Gaps = 5/111 (4%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQYYGVISIGT 416
IR+PLHR++ R + + EL +L G P PLSNY D QY+G I +GT
Sbjct: 27 IRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQYFGEIGLGT 86
Query: 417 PPQSFKVVFDTGSSNLWVPSKKCHYTNIACFCXXXXXXXXXXXXXXMGTQF 569
PPQ+F V FDTGSSNLWVPS++CH+ ++ C+ GT+F
Sbjct: 87 PPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKF 137
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 90.2 bits (214), Expect = 6e-18
Identities = 46/111 (41%), Positives = 63/111 (56%), Gaps = 5/111 (4%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIGT 416
IR+PL ++ R + + G EL +L G P PLS +LDAQY+G I +GT
Sbjct: 23 IRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLGT 82
Query: 417 PPQSFKVVFDTGSSNLWVPSKKCHYTNIACFCXXXXXXXXXXXXXXMGTQF 569
PPQ+F V FDTGSSNLWVPS++CH+ ++ C+ GT+F
Sbjct: 83 PPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKF 133
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 90.2 bits (214), Expect = 6e-18
Identities = 46/111 (41%), Positives = 63/111 (56%), Gaps = 5/111 (4%)
Frame = +3
Query: 252 IRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIGT 416
IR+PL ++ R + + G EL +L G P PLS +LDAQY+G I +GT
Sbjct: 27 IRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLGT 86
Query: 417 PPQSFKVVFDTGSSNLWVPSKKCHYTNIACFCXXXXXXXXXXXXXXMGTQF 569
PPQ+F V FDTGSSNLWVPS++CH+ ++ C+ GT+F
Sbjct: 87 PPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKF 137
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 81.0 bits (191), Expect = 4e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +3
Query: 366 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 81.0 bits (191), Expect = 4e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +3
Query: 366 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 81.0 bits (191), Expect = 4e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +3
Query: 366 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 81.0 bits (191), Expect = 4e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +3
Query: 366 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 81.0 bits (191), Expect = 4e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +3
Query: 366 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 81.0 bits (191), Expect = 4e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +3
Query: 366 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 81.0 bits (191), Expect = 4e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +3
Query: 366 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 81.0 bits (191), Expect = 4e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +3
Query: 366 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 81.0 bits (191), Expect = 4e-15
Identities = 34/47 (72%), Positives = 38/47 (80%)
Frame = +3
Query: 366 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTAC 124
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 76.6 bits (180), Expect = 8e-14
Identities = 34/49 (69%), Positives = 40/49 (81%)
Frame = +3
Query: 360 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 76.6 bits (180), Expect = 8e-14
Identities = 34/49 (69%), Positives = 40/49 (81%)
Frame = +3
Query: 360 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 76.6 bits (180), Expect = 8e-14
Identities = 34/49 (69%), Positives = 40/49 (81%)
Frame = +3
Query: 360 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 76.6 bits (180), Expect = 8e-14
Identities = 34/49 (69%), Positives = 40/49 (81%)
Frame = +3
Query: 360 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 76.6 bits (180), Expect = 8e-14
Identities = 34/49 (69%), Positives = 40/49 (81%)
Frame = +3
Query: 360 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 76.6 bits (180), Expect = 8e-14
Identities = 34/49 (69%), Positives = 40/49 (81%)
Frame = +3
Query: 360 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 76.6 bits (180), Expect = 8e-14
Identities = 34/49 (69%), Positives = 40/49 (81%)
Frame = +3
Query: 360 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPAC 114
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 76.2 bits (179), Expect = 1e-13
Identities = 44/92 (47%), Positives = 55/92 (59%), Gaps = 9/92 (9%)
Frame = +3
Query: 237 LRNGTIRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 389
L ++VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 485
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 76.2 bits (179), Expect = 1e-13
Identities = 44/92 (47%), Positives = 55/92 (59%), Gaps = 9/92 (9%)
Frame = +3
Query: 237 LRNGTIRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 389
L ++VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 485
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 76.2 bits (179), Expect = 1e-13
Identities = 44/92 (47%), Positives = 55/92 (59%), Gaps = 9/92 (9%)
Frame = +3
Query: 237 LRNGTIRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 389
L ++VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 11 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 69
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 485
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 70 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 101
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 76.2 bits (179), Expect = 1e-13
Identities = 44/92 (47%), Positives = 55/92 (59%), Gaps = 9/92 (9%)
Frame = +3
Query: 237 LRNGTIRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 389
L ++VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 485
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 76.2 bits (179), Expect = 1e-13
Identities = 44/92 (47%), Positives = 55/92 (59%), Gaps = 9/92 (9%)
Frame = +3
Query: 237 LRNGTIRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 389
L ++VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 485
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 76.2 bits (179), Expect = 1e-13
Identities = 44/92 (47%), Positives = 55/92 (59%), Gaps = 9/92 (9%)
Frame = +3
Query: 237 LRNGTIRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 389
L ++VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKC 485
Y+G ISIGTPPQ+F V+FDTGSSNLWVPS C
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSNLWVPSVYC 104
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 73.7 bits (173), Expect = 6e-13
Identities = 44/96 (45%), Positives = 55/96 (57%), Gaps = 12/96 (12%)
Frame = +3
Query: 255 RVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP-----EPLSNYLDAQYYG 398
+VPL R K+ R E G + L+ KY +P +PL NYLD +Y+G
Sbjct: 19 KVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLVDEQPLENYLDMEYFG 78
Query: 399 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
I IGTP Q F VVFDTGSSNLWVPS C +++AC
Sbjct: 79 TIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLAC 112
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 73.7 bits (173), Expect = 6e-13
Identities = 44/96 (45%), Positives = 55/96 (57%), Gaps = 12/96 (12%)
Frame = +3
Query: 255 RVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP-----EPLSNYLDAQYYG 398
+VPL R K+ R E G + L+ KY +P +PL NYLD +Y+G
Sbjct: 19 KVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLVDEQPLENYLDMEYFG 78
Query: 399 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
I IGTP Q F VVFDTGSSNLWVPS C +++AC
Sbjct: 79 TIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLAC 112
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 72.1 bits (169), Expect = 2e-12
Identities = 31/49 (63%), Positives = 38/49 (77%)
Frame = +3
Query: 360 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIAC 506
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++AC
Sbjct: 66 QPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLAC 112
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.5 bits (140), Expect = 6e-09
Identities = 38/85 (44%), Positives = 49/85 (57%), Gaps = 9/85 (10%)
Frame = +3
Query: 237 LRNGTIRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 389
L ++VPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 14 LEAAVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 72
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNL 464
Y+G ISIGTPPQ+F V+FDTGSS L
Sbjct: 73 YFGEISIGTPPQNFLVLFDTGSSPL 97
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 37.5 bits (83), Expect = 0.046
Identities = 27/64 (42%), Positives = 34/64 (53%), Gaps = 9/64 (14%)
Frame = +3
Query: 255 RVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYGVIS 407
RVPL + K+ R E G E LR KYD + EP++ Y+DA Y+G IS
Sbjct: 24 RVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFGEIS 82
Query: 408 IGTP 419
IGTP
Sbjct: 83 IGTP 86
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.24
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.24
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 35.1 bits (77), Expect = 0.24
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY + IGTPPQ +++ DTGSSN V
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAV 39
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.24
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.24
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.24
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 35.1 bits (77), Expect = 0.24
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 35.1 bits (77), Expect = 0.24
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.24
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.24
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 35.1 bits (77), Expect = 0.24
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY + IGTPPQ +++ DTGSSN V
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAV 118
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAV 88
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 34.7 bits (76), Expect = 0.32
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 390 YYGVISIGTPPQSFKVVFDTGSSNLWV 470
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAV 132
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 32.3 bits (70), Expect = 1.7
Identities = 13/21 (61%), Positives = 16/21 (76%)
Frame = +3
Query: 408 IGTPPQSFKVVFDTGSSNLWV 470
IGTPPQ +++ DTGSSN V
Sbjct: 3 IGTPPQKLQILVDTGSSNFAV 23
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 5.2
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -1
Query: 455 GSGVEYHLERLRRRADTDHSVVLSIK 378
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 30.3 bits (65), Expect = 6.9
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q+VPL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 30.3 bits (65), Expect = 6.9
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q+VPL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 30.3 bits (65), Expect = 6.9
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q+VPL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 30.3 bits (65), Expect = 6.9
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q+VPL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 30.3 bits (65), Expect = 6.9
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q+VPL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 30.3 bits (65), Expect = 6.9
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q+VPL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 30.3 bits (65), Expect = 6.9
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q+VPL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRVPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>AL121914-8|CAI19327.1| 106|Homo sapiens aurora kinase A protein.
Length = 106
Score = 29.9 bits (64), Expect = 9.1
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q++PL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>AL121914-7|CAM45839.1| 189|Homo sapiens aurora kinase A protein.
Length = 189
Score = 29.9 bits (64), Expect = 9.1
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q++PL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>AL121914-6|CAI19326.2| 147|Homo sapiens aurora kinase A protein.
Length = 147
Score = 29.9 bits (64), Expect = 9.1
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q++PL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>AL121914-5|CAI19324.1| 271|Homo sapiens aurora kinase A protein.
Length = 271
Score = 29.9 bits (64), Expect = 9.1
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q++PL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 29.9 bits (64), Expect = 9.1
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q++PL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 29.9 bits (64), Expect = 9.1
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q++PL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 29.9 bits (64), Expect = 9.1
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Frame = +2
Query: 428 VQGGIRHRILQPLGAFQKVPLHQHRLF-LHNKYDSRKSKTYVANG--HPVSR 574
V G R+L P + Q++PL +L H ++K K A HPVSR
Sbjct: 39 VNSGQAQRVLCPSNSSQRIPLQAQKLVSSHKPVQNQKQKQLQATSVPHPVSR 90
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,977,419
Number of Sequences: 237096
Number of extensions: 2255477
Number of successful extensions: 4934
Number of sequences better than 10.0: 82
Number of HSP's better than 10.0 without gapping: 4707
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4919
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8063224416
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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