Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmte15p19
(836 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 146 9e-35
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 146 9e-35
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 146 9e-35
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 143 8e-34
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 142 1e-33
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 131 3e-30
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 128 3e-29
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 128 3e-29
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 128 3e-29
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 128 3e-29
BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family... 126 1e-28
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 126 1e-28
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 124 4e-28
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 124 4e-28
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 124 4e-28
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 124 4e-28
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 124 4e-28
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 124 4e-28
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 124 4e-28
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 124 4e-28
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 124 4e-28
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 119 2e-26
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 119 2e-26
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 119 2e-26
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 119 2e-26
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 99 2e-20
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 99 2e-20
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 99 2e-20
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 99 2e-20
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 99 2e-20
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 99 2e-20
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 99 2e-20
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 99 2e-20
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 99 2e-20
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 99 2e-20
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 99 2e-20
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 99 2e-20
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 99 2e-20
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 99 2e-20
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 97 7e-20
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 96 1e-19
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 96 1e-19
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 96 1e-19
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 96 1e-19
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 93 1e-18
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 93 1e-18
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 92 2e-18
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 92 2e-18
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 92 2e-18
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 92 2e-18
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 92 2e-18
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 91 3e-18
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 91 3e-18
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 91 5e-18
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 91 6e-18
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 91 6e-18
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 91 6e-18
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 91 6e-18
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 91 6e-18
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 91 6e-18
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 91 6e-18
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 91 6e-18
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 91 6e-18
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 91 6e-18
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 90 8e-18
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 90 8e-18
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 90 8e-18
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 90 8e-18
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 90 8e-18
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 90 8e-18
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 90 1e-17
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 90 1e-17
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 89 1e-17
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 89 2e-17
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 89 2e-17
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 88 4e-17
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 88 4e-17
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 88 4e-17
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 88 4e-17
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 87 6e-17
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 87 6e-17
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 87 6e-17
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 86 1e-16
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 86 1e-16
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 85 2e-16
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 85 2e-16
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 85 3e-16
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 85 3e-16
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 85 3e-16
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 85 3e-16
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 85 3e-16
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 85 3e-16
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 85 3e-16
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 85 3e-16
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 85 3e-16
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 85 3e-16
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 85 4e-16
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 85 4e-16
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 85 4e-16
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 85 4e-16
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 84 5e-16
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 84 5e-16
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 84 5e-16
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 84 5e-16
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 84 5e-16
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 84 5e-16
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 84 5e-16
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 84 5e-16
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 84 5e-16
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 83 1e-15
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 83 1e-15
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 83 1e-15
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 83 1e-15
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 83 2e-15
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 82 3e-15
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 82 3e-15
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 82 3e-15
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 82 3e-15
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 82 3e-15
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 82 3e-15
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 82 3e-15
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 82 3e-15
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 82 3e-15
BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 82 3e-15
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 82 3e-15
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 82 3e-15
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 82 3e-15
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 82 3e-15
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 82 3e-15
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 82 3e-15
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 82 3e-15
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 82 3e-15
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 82 3e-15
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 82 3e-15
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 82 3e-15
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 82 3e-15
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 82 3e-15
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 82 3e-15
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 82 3e-15
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 82 3e-15
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 82 3e-15
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 82 3e-15
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 82 3e-15
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 82 3e-15
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 82 3e-15
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 82 3e-15
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 82 3e-15
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 82 3e-15
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 82 3e-15
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 82 3e-15
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 82 3e-15
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 82 3e-15
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 81 4e-15
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 81 4e-15
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 81 4e-15
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 81 4e-15
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 81 4e-15
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 81 4e-15
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 81 4e-15
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 81 4e-15
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 81 4e-15
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 81 4e-15
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 81 5e-15
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 81 5e-15
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 81 5e-15
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 81 6e-15
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 81 6e-15
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 81 6e-15
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 80 9e-15
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 80 9e-15
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 80 9e-15
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 80 9e-15
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 80 1e-14
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 80 1e-14
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 80 1e-14
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 80 1e-14
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 80 1e-14
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 80 1e-14
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 80 1e-14
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 80 1e-14
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 80 1e-14
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 80 1e-14
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 80 1e-14
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 80 1e-14
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 80 1e-14
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 80 1e-14
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 80 1e-14
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 79 1e-14
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 79 1e-14
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 79 1e-14
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 79 1e-14
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 79 1e-14
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 79 1e-14
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 79 1e-14
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 79 1e-14
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 79 1e-14
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 79 1e-14
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 79 3e-14
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 78 3e-14
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 78 3e-14
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 78 3e-14
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 78 5e-14
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 77 6e-14
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 77 6e-14
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 77 6e-14
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 77 6e-14
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 77 8e-14
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 77 8e-14
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 76 1e-13
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 76 1e-13
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 76 1e-13
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 76 1e-13
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 76 1e-13
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 76 1e-13
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 76 1e-13
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 76 1e-13
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 76 1e-13
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 76 1e-13
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 76 1e-13
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 76 1e-13
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 76 1e-13
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 76 1e-13
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 75 2e-13
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 75 2e-13
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 75 3e-13
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 75 3e-13
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 75 3e-13
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 75 3e-13
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 75 3e-13
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 75 3e-13
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 75 3e-13
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 75 3e-13
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 75 3e-13
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 75 3e-13
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 75 3e-13
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 75 3e-13
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 75 3e-13
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 75 4e-13
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 75 4e-13
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 74 7e-13
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 73 1e-12
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 73 1e-12
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 73 1e-12
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 73 1e-12
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 73 1e-12
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 73 1e-12
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 73 1e-12
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 73 1e-12
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 73 1e-12
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 73 1e-12
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 73 1e-12
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 73 2e-12
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 73 2e-12
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 73 2e-12
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 73 2e-12
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 73 2e-12
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 73 2e-12
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 73 2e-12
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 73 2e-12
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 73 2e-12
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 73 2e-12
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 72 3e-12
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 72 3e-12
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 72 3e-12
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 71 4e-12
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 71 4e-12
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 71 4e-12
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 4e-12
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 4e-12
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 4e-12
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 4e-12
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 4e-12
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 4e-12
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 4e-12
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 71 4e-12
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 71 4e-12
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 71 4e-12
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 71 4e-12
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 71 4e-12
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 71 5e-12
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 71 5e-12
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 71 5e-12
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 5e-12
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 5e-12
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 71 5e-12
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 5e-12
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 5e-12
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 5e-12
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 5e-12
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 5e-12
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 71 5e-12
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 71 5e-12
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 71 5e-12
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 71 5e-12
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 71 5e-12
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 71 5e-12
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 71 5e-12
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 71 7e-12
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 71 7e-12
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 70 1e-11
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 69 2e-11
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 69 2e-11
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 69 2e-11
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 69 2e-11
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 69 2e-11
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 69 3e-11
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 68 4e-11
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 67 9e-11
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 65 3e-10
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 65 3e-10
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 65 3e-10
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 65 3e-10
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 65 3e-10
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 65 3e-10
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 65 3e-10
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 65 3e-10
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 65 3e-10
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 65 3e-10
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 65 3e-10
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 65 3e-10
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 65 3e-10
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 65 3e-10
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 64 8e-10
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 64 8e-10
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 63 1e-09
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 63 1e-09
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 63 1e-09
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 62 2e-09
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 62 2e-09
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 62 2e-09
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 62 3e-09
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 61 6e-09
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 61 6e-09
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 61 6e-09
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 61 6e-09
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 61 6e-09
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 61 6e-09
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 61 6e-09
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 61 6e-09
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 61 6e-09
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 60 7e-09
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 60 7e-09
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 60 7e-09
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 60 7e-09
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 60 7e-09
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 60 7e-09
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 60 7e-09
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 60 7e-09
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 60 7e-09
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 60 7e-09
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 60 7e-09
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 60 1e-08
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 60 1e-08
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 60 1e-08
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 60 1e-08
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 60 1e-08
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 59 2e-08
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 59 2e-08
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 59 2e-08
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 59 2e-08
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 59 2e-08
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 59 2e-08
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 59 2e-08
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 59 2e-08
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 59 2e-08
BC128535-1|AAI28536.1| 143|Homo sapiens CYP21A2 protein protein. 58 4e-08
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 58 4e-08
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 58 4e-08
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 56 1e-07
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 56 2e-07
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 56 2e-07
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 55 3e-07
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 55 3e-07
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 55 4e-07
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 53 1e-06
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 53 1e-06
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 53 1e-06
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 53 1e-06
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 53 1e-06
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 52 2e-06
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 52 3e-06
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 52 3e-06
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 51 5e-06
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 51 5e-06
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 51 6e-06
AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 50 8e-06
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 50 1e-05
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 50 1e-05
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 50 1e-05
AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 50 1e-05
BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 49 2e-05
BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 49 2e-05
BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 49 2e-05
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 48 3e-05
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 47 1e-04
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 46 1e-04
AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 45 3e-04
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 45 4e-04
EF122244-1|ABO41979.1| 216|Homo sapiens cytochrome P450 2F1 var... 43 0.001
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 43 0.001
S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 43 0.002
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 43 0.002
AC011737-1|AAX88915.1| 382|Homo sapiens unknown protein. 42 0.004
D84124-1|BAA28219.1| 509|Homo sapiens prostacyclin synthase pro... 41 0.005
D83402-1|BAA11910.1| 500|Homo sapiens prostacyclin synthase pro... 41 0.005
D38145-1|BAA07343.1| 500|Homo sapiens prostacyclin synthase pro... 41 0.005
BC101811-1|AAI01812.1| 500|Homo sapiens prostaglandin I2 (prost... 41 0.005
BC101809-1|AAI01810.1| 500|Homo sapiens prostaglandin I2 (prost... 41 0.005
AL118525-1|CAC14162.1| 500|Homo sapiens prostaglandin I2 (prost... 41 0.005
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 41 0.005
AF297051-1|AAG31784.1| 500|Homo sapiens prostacyclin synthase p... 41 0.005
AF297050-1|AAG31783.1| 500|Homo sapiens prostacyclin synthase p... 41 0.005
AF297049-1|AAG31782.1| 500|Homo sapiens prostacyclin synthase p... 41 0.005
AF297048-1|AAG31781.1| 500|Homo sapiens prostacyclin synthase p... 41 0.005
AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens ... 39 0.020
AF297052-1|AAG31785.1| 500|Homo sapiens prostacyclin synthase p... 39 0.026
BC056258-1|AAH56258.1| 359|Homo sapiens CYP19A1 protein protein. 38 0.034
BC020767-1|AAH20767.1| 360|Homo sapiens Unknown (protein for IM... 38 0.034
BC067441-1|AAH67441.1| 501|Homo sapiens cytochrome P450, family... 37 0.10
BC067434-1|AAH67434.1| 501|Homo sapiens cytochrome P450, family... 37 0.10
X56088-1|CAA39568.1| 504|Homo sapiens cholesterol 7-alpha-hydr... 36 0.14
M93133-1|AAA58435.1| 504|Homo sapiens cholesterol 7-alpha hydro... 36 0.24
BC112184-1|AAI12185.1| 504|Homo sapiens cytochrome P450, family... 36 0.24
BC101777-1|AAI01778.1| 504|Homo sapiens cytochrome P450, family... 36 0.24
BC067444-1|AAH67444.1| 501|Homo sapiens cytochrome P450, family... 34 0.56
BC067442-1|AAH67442.1| 501|Homo sapiens cytochrome P450, family... 34 0.56
AF090320-1|AAD19877.1| 501|Homo sapiens sterol 12-alpha-hydroxy... 34 0.56
AF090318-1|AAC63037.1| 462|Homo sapiens sterol 12-alpha hydroxy... 34 0.56
AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 33 0.97
AY037304-1|AAK69827.1| 300|Homo sapiens lymphocyte/NHL galectin... 33 1.7
AF468213-1|AAL77076.1| 359|Homo sapiens lymphocyte/NHL galectin... 33 1.7
AB051763-1|BAB18572.1| 677|Homo sapiens NADPH-cytochrome P-450 ... 31 6.8
S90469-1|AAB21814.1| 676|Homo sapiens cytochrome P450 reductase... 30 9.0
DQ640499-1|ABF70199.1| 677|Homo sapiens P450 (cytochrome) oxido... 30 9.0
BC034277-1|AAH34277.1| 680|Homo sapiens P450 (cytochrome) oxido... 30 9.0
AF258341-1|AAG09798.1| 677|Homo sapiens NADPH-cytochrome P450 r... 30 9.0
AB209874-1|BAD93111.1| 686|Homo sapiens Hypothetical protein DK... 30 9.0
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 146 bits (354), Expect = 9e-35
Identities = 78/257 (30%), Positives = 143/257 (55%), Gaps = 1/257 (0%)
Frame = -2
Query: 820 LWSNTVIVWIV*LANTSWRPEQAISYKAKEIEEQYPNSNILINAMLLGQEKMNPEDIATV 641
+W + + W +T ++ +A E Q P+++ L + + Q +++ +++
Sbjct: 125 VWQDHTLAW-----DTIFKSVKACIDNRLEKYSQQPSADFLCD--IYHQNRLSKKELYAA 177
Query: 640 IMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQ 461
+ ++ L V T +S ++LY L++ + Q+ L KEIQ PE ++ +R PYL+
Sbjct: 178 VTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNM-PYLK 236
Query: 460 ACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPE 281
AC+KE++RLTP +P TR L K L +Y +P+GT+++++TQ E N++D++ F PE
Sbjct: 237 ACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPE 296
Query: 280 RWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYHYGD-LEPTR 104
RWL+ + + + FA +PFG G R C+G+ +AE + L +++KY ++ + +E
Sbjct: 297 RWLQ-EKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVEMLH 355
Query: 103 SFIARPKRALKLRFIDR 53
S P R L + F R
Sbjct: 356 SGTLVPSRELPIAFCQR 372
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family 24,
subfamily A, polypeptide 1 protein.
Length = 514
Score = 146 bits (354), Expect = 9e-35
Identities = 78/257 (30%), Positives = 143/257 (55%), Gaps = 1/257 (0%)
Frame = -2
Query: 820 LWSNTVIVWIV*LANTSWRPEQAISYKAKEIEEQYPNSNILINAMLLGQEKMNPEDIATV 641
+W + + W +T ++ +A E Q P+++ L + + Q +++ +++
Sbjct: 267 VWQDHTLAW-----DTIFKSVKACIDNRLEKYSQQPSADFLCD--IYHQNRLSKKELYAA 319
Query: 640 IMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQ 461
+ ++ L V T +S ++LY L++ + Q+ L KEIQ PE ++ +R PYL+
Sbjct: 320 VTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNM-PYLK 378
Query: 460 ACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPE 281
AC+KE++RLTP +P TR L K L +Y +P+GT+++++TQ E N++D++ F PE
Sbjct: 379 ACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPE 438
Query: 280 RWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYHYGD-LEPTR 104
RWL+ + + + FA +PFG G R C+G+ +AE + L +++KY ++ + +E
Sbjct: 439 RWLQ-EKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVEMLH 497
Query: 103 SFIARPKRALKLRFIDR 53
S P R L + F R
Sbjct: 498 SGTLVPSRELPIAFCQR 514
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 146 bits (354), Expect = 9e-35
Identities = 78/257 (30%), Positives = 143/257 (55%), Gaps = 1/257 (0%)
Frame = -2
Query: 820 LWSNTVIVWIV*LANTSWRPEQAISYKAKEIEEQYPNSNILINAMLLGQEKMNPEDIATV 641
+W + + W +T ++ +A E Q P+++ L + + Q +++ +++
Sbjct: 125 VWQDHTLAW-----DTIFKSVKACIDNRLEKYSQQPSADFLCD--IYHQNRLSKKELYAA 177
Query: 640 IMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQ 461
+ ++ L V T +S ++LY L++ + Q+ L KEIQ PE ++ +R PYL+
Sbjct: 178 VTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNM-PYLK 236
Query: 460 ACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPE 281
AC+KE++RLTP +P TR L K L +Y +P+GT+++++TQ E N++D++ F PE
Sbjct: 237 ACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPE 296
Query: 280 RWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYHYGD-LEPTR 104
RWL+ + + + FA +PFG G R C+G+ +AE + L +++KY ++ + +E
Sbjct: 297 RWLQ-EKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVEMLH 355
Query: 103 SFIARPKRALKLRFIDR 53
S P R L + F R
Sbjct: 356 SGTLVPSRELPIAFCQR 372
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 143 bits (346), Expect = 8e-34
Identities = 71/229 (31%), Positives = 133/229 (58%)
Frame = -2
Query: 820 LWSNTVIVWIV*LANTSWRPEQAISYKAKEIEEQYPNSNILINAMLLGQEKMNPEDIATV 641
+W + + W +T ++ +A E Q P+++ L + + Q +++ +++
Sbjct: 10 VWQDHTLAW-----DTIFKSVKACIDNRLEKYSQQPSADFLCD--IYHQNRLSKKELYAA 62
Query: 640 IMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQ 461
+ ++ L V T +S ++LY L++ + Q+ L KEIQ PE ++ +R PYL+
Sbjct: 63 VTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNM-PYLK 121
Query: 460 ACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPE 281
AC+KE++RLTP +P TR L K L +Y +P+GT+++++TQ E N++D++ F PE
Sbjct: 122 ACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPE 181
Query: 280 RWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
RWL+ + + + FA +PFG G R C+G+ +AE + L +++KY ++
Sbjct: 182 RWLQ-EKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQ 229
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 142 bits (344), Expect = 1e-33
Identities = 78/257 (30%), Positives = 141/257 (54%), Gaps = 1/257 (0%)
Frame = -2
Query: 820 LWSNTVIVWIV*LANTSWRPEQAISYKAKEIEEQYPNSNILINAMLLGQEKMNPEDIATV 641
+W + W +T ++ +A E Q P+++ L + + Q +++ +++
Sbjct: 266 VWQGHTLAW-----DTIFKSVKACIDNRLEKYSQQPSADFLCD--IYHQNRLSKKELYAA 318
Query: 640 IMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQ 461
+ ++ L V T +S ++LY L++ + Q+ L KEIQ PE + +R PYL+
Sbjct: 319 VTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRPREEDLRNM-PYLK 377
Query: 460 ACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPE 281
AC+KE++RLTP +P TR L K L +Y +P+GT+++++TQ E N++D++ F PE
Sbjct: 378 ACLKESMRLTPGVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPE 437
Query: 280 RWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYHYGD-LEPTR 104
RWL+ + + + FA +PFG G R C+G+ +AE + L +++KY ++ + +E
Sbjct: 438 RWLQ-EKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPVEMLH 496
Query: 103 SFIARPKRALKLRFIDR 53
S P R L + F R
Sbjct: 497 SGTLVPSRELPIAFCQR 513
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 131 bits (317), Expect = 3e-30
Identities = 71/217 (32%), Positives = 120/217 (55%), Gaps = 6/217 (2%)
Frame = -2
Query: 685 LLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK 506
LL +++P + + ++L+ GV+T +++ ++ LY+L+K + QK L++E+ P +
Sbjct: 314 LLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQ 373
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ K P L+A +KETLRL P +P +RI+ K I +D + P+ T + + S
Sbjct: 374 VPQ-HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYEVS 432
Query: 325 LKESNYDDANTFCPERWLKSDS----NEYHLFASIPFGYGARKCLGQNIAETMMSLLTVK 158
+ + + +F P RWL++ H F S+PFGYG R CLG+ IAE M LL +
Sbjct: 433 RDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLAR 492
Query: 157 LLQKYK--LEYHYGDLEPTRSFIARPKRALKLRFIDR 53
L+QKYK L G+L+ + P + + L+F+ R
Sbjct: 493 LIQKYKVVLAPETGELKSVARIVLVPNKKVGLQFLQR 529
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 128 bits (308), Expect = 3e-29
Identities = 70/217 (32%), Positives = 119/217 (54%), Gaps = 6/217 (2%)
Frame = -2
Query: 685 LLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK 506
LL +++P + + ++L+ GV+T +++ ++ LY+L+K + Q+ L++E+ P +
Sbjct: 313 LLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQ 372
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ K P L+A +KETLRL P +P +RI+ K I +D + P+ T + S
Sbjct: 373 VPQ-HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVS 431
Query: 325 LKESNYDDANTFCPERWLKSDSNE----YHLFASIPFGYGARKCLGQNIAETMMSLLTVK 158
+ + + +F P RWL++ H F S+PFGYG R CLG+ IAE M LL +
Sbjct: 432 RDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLAR 491
Query: 157 LLQKYK--LEYHYGDLEPTRSFIARPKRALKLRFIDR 53
L+QKYK L G+L+ + P + + L+F+ R
Sbjct: 492 LIQKYKVVLAPETGELKSVARIVLVPNKKVGLQFLQR 528
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 128 bits (308), Expect = 3e-29
Identities = 70/217 (32%), Positives = 119/217 (54%), Gaps = 6/217 (2%)
Frame = -2
Query: 685 LLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK 506
LL +++P + + ++L+ GV+T +++ ++ LY+L+K + Q+ L++E+ P +
Sbjct: 314 LLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQ 373
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ K P L+A +KETLRL P +P +RI+ K I +D + P+ T + S
Sbjct: 374 VPQ-HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVS 432
Query: 325 LKESNYDDANTFCPERWLKSDSNE----YHLFASIPFGYGARKCLGQNIAETMMSLLTVK 158
+ + + +F P RWL++ H F S+PFGYG R CLG+ IAE M LL +
Sbjct: 433 RDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLAR 492
Query: 157 LLQKYK--LEYHYGDLEPTRSFIARPKRALKLRFIDR 53
L+QKYK L G+L+ + P + + L+F+ R
Sbjct: 493 LIQKYKVVLAPETGELKSVARIVLVPNKKVGLQFLQR 529
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 128 bits (308), Expect = 3e-29
Identities = 70/217 (32%), Positives = 119/217 (54%), Gaps = 6/217 (2%)
Frame = -2
Query: 685 LLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK 506
LL +++P + + ++L+ GV+T +++ ++ LY+L+K + Q+ L++E+ P +
Sbjct: 314 LLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQ 373
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ K P L+A +KETLRL P +P +RI+ K I +D + P+ T + S
Sbjct: 374 VPQ-HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVS 432
Query: 325 LKESNYDDANTFCPERWLKSDSNE----YHLFASIPFGYGARKCLGQNIAETMMSLLTVK 158
+ + + +F P RWL++ H F S+PFGYG R CLG+ IAE M LL +
Sbjct: 433 RDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLAR 492
Query: 157 LLQKYK--LEYHYGDLEPTRSFIARPKRALKLRFIDR 53
L+QKYK L G+L+ + P + + L+F+ R
Sbjct: 493 LIQKYKVVLAPETGELKSVARIVLVPNKKVGLQFLQR 529
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 128 bits (308), Expect = 3e-29
Identities = 70/217 (32%), Positives = 119/217 (54%), Gaps = 6/217 (2%)
Frame = -2
Query: 685 LLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK 506
LL +++P + + ++L+ GV+T +++ ++ LY+L+K + Q+ L++E+ P +
Sbjct: 314 LLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQ 373
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ K P L+A +KETLRL P +P +RI+ K I +D + P+ T + S
Sbjct: 374 VPQ-HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVS 432
Query: 325 LKESNYDDANTFCPERWLKSDSNE----YHLFASIPFGYGARKCLGQNIAETMMSLLTVK 158
+ + + +F P RWL++ H F S+PFGYG R CLG+ IAE M LL +
Sbjct: 433 RDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLAR 492
Query: 157 LLQKYK--LEYHYGDLEPTRSFIARPKRALKLRFIDR 53
L+QKYK L G+L+ + P + + L+F+ R
Sbjct: 493 LIQKYKVVLAPETGELKSVARIVLVPNKKVGLQFLQR 529
>BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family
27, subfamily C, polypeptide 1 protein.
Length = 372
Score = 126 bits (303), Expect = 1e-28
Identities = 64/190 (33%), Positives = 114/190 (60%), Gaps = 1/190 (0%)
Frame = -2
Query: 700 LINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQEN 521
L+ + L Q + ++I + +MLL GV+T + + S+ +Y LA++ + Q+ +Y+EI +N
Sbjct: 155 LLTYLFLSQA-LTLQEIYANVTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKN 213
Query: 520 FPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMS 341
E+ + + + P ++A +KETLRL P +P R+ +++ + Y IP+GT + +
Sbjct: 214 LGERHVPTAADV-PKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALC 272
Query: 340 TQDASLKESNYDDANTFCPERWL-KSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLT 164
S ++ N+ A F PERWL K D + F SIPFG+G R C+G+ IAE + L+
Sbjct: 273 HYATSYQDENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVV 332
Query: 163 VKLLQKYKLE 134
++LLQ ++++
Sbjct: 333 IQLLQHFEIK 342
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 126 bits (303), Expect = 1e-28
Identities = 64/190 (33%), Positives = 114/190 (60%), Gaps = 1/190 (0%)
Frame = -2
Query: 700 LINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQEN 521
L+ + L Q + ++I + +MLL GV+T + + S+ +Y LA++ + Q+ +Y+EI +N
Sbjct: 155 LLTYLFLSQA-LTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKN 213
Query: 520 FPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMS 341
E+ + + + P ++A +KETLRL P +P R+ +++ + Y IP+GT + +
Sbjct: 214 LGERHVPTAADV-PKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALC 272
Query: 340 TQDASLKESNYDDANTFCPERWL-KSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLT 164
S ++ N+ A F PERWL K D + F SIPFG+G R C+G+ IAE + L+
Sbjct: 273 HYATSYQDENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVV 332
Query: 163 VKLLQKYKLE 134
++LLQ ++++
Sbjct: 333 IQLLQHFEIK 342
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 124 bits (299), Expect = 4e-28
Identities = 65/213 (30%), Positives = 119/213 (55%), Gaps = 3/213 (1%)
Frame = -2
Query: 682 LGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQK 506
L +E++ + I + ++LL GV+T++++ S+ LY L+++ + Q L+ EI P
Sbjct: 297 LFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSS 356
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ Q P L+A +KE LRL P +P +R+ K+I + Y IP+ TL+ + S
Sbjct: 357 AYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATS 416
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + N+F P RWL + H FAS+PFG+G R C+G+ +AE + + ++L
Sbjct: 417 RDPAQFPEPNSFRPARWL-GEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTH 475
Query: 145 YKLEYHYG--DLEPTRSFIARPKRALKLRFIDR 53
++++ G + P + P+R++ L+F+DR
Sbjct: 476 FEVQPEPGAAPVRPKTRTVLVPERSINLQFLDR 508
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 124 bits (299), Expect = 4e-28
Identities = 65/213 (30%), Positives = 119/213 (55%), Gaps = 3/213 (1%)
Frame = -2
Query: 682 LGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQK 506
L +E++ + I + ++LL GV+T++++ S+ LY L+++ + Q L+ EI P
Sbjct: 297 LFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSS 356
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ Q P L+A +KE LRL P +P +R+ K+I + Y IP+ TL+ + S
Sbjct: 357 AYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATS 416
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + N+F P RWL + H FAS+PFG+G R C+G+ +AE + + ++L
Sbjct: 417 RDPAQFPEPNSFRPARWL-GEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTH 475
Query: 145 YKLEYHYG--DLEPTRSFIARPKRALKLRFIDR 53
++++ G + P + P+R++ L+F+DR
Sbjct: 476 FEVQPEPGAAPVRPKTRTVLVPERSINLQFLDR 508
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 124 bits (299), Expect = 4e-28
Identities = 65/213 (30%), Positives = 119/213 (55%), Gaps = 3/213 (1%)
Frame = -2
Query: 682 LGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQK 506
L +E++ + I + ++LL GV+T++++ S+ LY L+++ + Q L+ EI P
Sbjct: 297 LFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSS 356
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ Q P L+A +KE LRL P +P +R+ K+I + Y IP+ TL+ + S
Sbjct: 357 AYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATS 416
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + N+F P RWL + H FAS+PFG+G R C+G+ +AE + + ++L
Sbjct: 417 RDPAQFPEPNSFRPARWL-GEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTH 475
Query: 145 YKLEYHYG--DLEPTRSFIARPKRALKLRFIDR 53
++++ G + P + P+R++ L+F+DR
Sbjct: 476 FEVQPEPGAAPVRPKTRTVLVPERSINLQFLDR 508
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 124 bits (299), Expect = 4e-28
Identities = 65/213 (30%), Positives = 119/213 (55%), Gaps = 3/213 (1%)
Frame = -2
Query: 682 LGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQK 506
L +E++ + I + ++LL GV+T++++ S+ LY L+++ + Q L+ EI P
Sbjct: 297 LFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSS 356
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ Q P L+A +KE LRL P +P +R+ K+I + Y IP+ TL+ + S
Sbjct: 357 AYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATS 416
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + N+F P RWL + H FAS+PFG+G R C+G+ +AE + + ++L
Sbjct: 417 RDPAQFPEPNSFRPARWL-GEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTH 475
Query: 145 YKLEYHYG--DLEPTRSFIARPKRALKLRFIDR 53
++++ G + P + P+R++ L+F+DR
Sbjct: 476 FEVQPEPGAAPVRPKTRTVLVPERSINLQFLDR 508
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 124 bits (299), Expect = 4e-28
Identities = 65/213 (30%), Positives = 119/213 (55%), Gaps = 3/213 (1%)
Frame = -2
Query: 682 LGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQK 506
L +E++ + I + ++LL GV+T++++ S+ LY L+++ + Q L+ EI P
Sbjct: 297 LFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSS 356
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ Q P L+A +KE LRL P +P +R+ K+I + Y IP+ TL+ + S
Sbjct: 357 AYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATS 416
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + N+F P RWL + H FAS+PFG+G R C+G+ +AE + + ++L
Sbjct: 417 RDPAQFPEPNSFRPARWL-GEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTH 475
Query: 145 YKLEYHYG--DLEPTRSFIARPKRALKLRFIDR 53
++++ G + P + P+R++ L+F+DR
Sbjct: 476 FEVQPEPGAAPVRPKTRTVLVPERSINLQFLDR 508
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 124 bits (299), Expect = 4e-28
Identities = 65/213 (30%), Positives = 119/213 (55%), Gaps = 3/213 (1%)
Frame = -2
Query: 682 LGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQK 506
L +E++ + I + ++LL GV+T++++ S+ LY L+++ + Q L+ EI P
Sbjct: 297 LFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSS 356
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ Q P L+A +KE LRL P +P +R+ K+I + Y IP+ TL+ + S
Sbjct: 357 AYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATS 416
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + N+F P RWL + H FAS+PFG+G R C+G+ +AE + + ++L
Sbjct: 417 RDPAQFPEPNSFRPARWL-GEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTH 475
Query: 145 YKLEYHYG--DLEPTRSFIARPKRALKLRFIDR 53
++++ G + P + P+R++ L+F+DR
Sbjct: 476 FEVQPEPGAAPVRPKTRTVLVPERSINLQFLDR 508
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 124 bits (299), Expect = 4e-28
Identities = 65/213 (30%), Positives = 119/213 (55%), Gaps = 3/213 (1%)
Frame = -2
Query: 682 LGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQK 506
L +E++ + I + ++LL GV+T++++ S+ LY L+++ + Q L+ EI P
Sbjct: 297 LFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSS 356
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ Q P L+A +KE LRL P +P +R+ K+I + Y IP+ TL+ + S
Sbjct: 357 AYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATS 416
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + N+F P RWL + H FAS+PFG+G R C+G+ +AE + + ++L
Sbjct: 417 RDPAQFPEPNSFRPARWL-GEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTH 475
Query: 145 YKLEYHYG--DLEPTRSFIARPKRALKLRFIDR 53
++++ G + P + P+R++ L+F+DR
Sbjct: 476 FEVQPEPGAAPVRPKTRTVLVPERSINLQFLDR 508
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 124 bits (299), Expect = 4e-28
Identities = 65/213 (30%), Positives = 119/213 (55%), Gaps = 3/213 (1%)
Frame = -2
Query: 682 LGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQK 506
L +E++ + I + ++LL GV+T++++ S+ LY L+++ + Q L+ EI P
Sbjct: 297 LFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSS 356
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ Q P L+A +KE LRL P +P +R+ K+I + Y IP+ TL+ + S
Sbjct: 357 AYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATS 416
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + N+F P RWL + H FAS+PFG+G R C+G+ +AE + + ++L
Sbjct: 417 RDPAQFPEPNSFRPARWL-GEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTH 475
Query: 145 YKLEYHYG--DLEPTRSFIARPKRALKLRFIDR 53
++++ G + P + P+R++ L+F+DR
Sbjct: 476 FEVQPEPGAAPVRPKTRTVLVPERSINLQFLDR 508
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 124 bits (299), Expect = 4e-28
Identities = 65/213 (30%), Positives = 119/213 (55%), Gaps = 3/213 (1%)
Frame = -2
Query: 682 LGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQK 506
L +E++ + I + ++LL GV+T++++ S+ LY L+++ + Q L+ EI P
Sbjct: 297 LFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSS 356
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
+ Q P L+A +KE LRL P +P +R+ K+I + Y IP+ TL+ + S
Sbjct: 357 AYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATS 416
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + N+F P RWL + H FAS+PFG+G R C+G+ +AE + + ++L
Sbjct: 417 RDPAQFPEPNSFRPARWL-GEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTH 475
Query: 145 YKLEYHYG--DLEPTRSFIARPKRALKLRFIDR 53
++++ G + P + P+R++ L+F+DR
Sbjct: 476 FEVQPEPGAAPVRPKTRTVLVPERSINLQFLDR 508
>X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein.
Length = 521
Score = 119 bits (286), Expect = 2e-26
Identities = 70/209 (33%), Positives = 112/209 (53%), Gaps = 1/209 (0%)
Frame = -2
Query: 685 LLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK 506
LLG KM+ EDI + +ML GV+T + + + LY +A+ K Q +L E+ Q
Sbjct: 305 LLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAA-RHQA 363
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
D+ + + P L+A IKETLRL P L R L ++ L Y IP TL+ ++
Sbjct: 364 QGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALG 423
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + D F P RWL D N + F ++ FG+G R+CLG+ IAE M++ + +L+
Sbjct: 424 REPTFFFDPENFDPTRWLSKDKNITY-FRNLGFGWGVRQCLGRRIAELEMTIFLINMLEN 482
Query: 145 YKLE-YHYGDLEPTRSFIARPKRALKLRF 62
+++E H D+ T + I P++ + F
Sbjct: 483 FRVEIQHLSDVGTTFNLILMPEKPISFTF 511
>M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc
protein.
Length = 239
Score = 119 bits (286), Expect = 2e-26
Identities = 70/209 (33%), Positives = 112/209 (53%), Gaps = 1/209 (0%)
Frame = -2
Query: 685 LLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK 506
LLG KM+ EDI + +ML GV+T + + + LY +A+ K Q +L E+ Q
Sbjct: 23 LLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAA-RHQA 81
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
D+ + + P L+A IKETLRL P L R L ++ L Y IP TL+ ++
Sbjct: 82 QGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALG 141
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + D F P RWL D N + F ++ FG+G R+CLG+ IAE M++ + +L+
Sbjct: 142 REPTFFFDPENFDPTRWLSKDKNITY-FRNLGFGWGVRQCLGRRIAELEMTIFLINMLEN 200
Query: 145 YKLE-YHYGDLEPTRSFIARPKRALKLRF 62
+++E H D+ T + I P++ + F
Sbjct: 201 FRVEIQHLSDVGTTFNLILMPEKPISFTF 229
>M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein.
Length = 521
Score = 119 bits (286), Expect = 2e-26
Identities = 70/209 (33%), Positives = 112/209 (53%), Gaps = 1/209 (0%)
Frame = -2
Query: 685 LLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK 506
LLG KM+ EDI + +ML GV+T + + + LY +A+ K Q +L E+ Q
Sbjct: 305 LLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAA-RHQA 363
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
D+ + + P L+A IKETLRL P L R L ++ L Y IP TL+ ++
Sbjct: 364 QGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALG 423
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + D F P RWL D N + F ++ FG+G R+CLG+ IAE M++ + +L+
Sbjct: 424 REPTFFFDPENFDPTRWLSKDKNITY-FRNLGFGWGVRQCLGRRIAELEMTIFLINMLEN 482
Query: 145 YKLE-YHYGDLEPTRSFIARPKRALKLRF 62
+++E H D+ T + I P++ + F
Sbjct: 483 FRVEIQHLSDVGTTFNLILMPEKPISFTF 511
>BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family
11, subfamily A, polypeptide 1 protein.
Length = 521
Score = 119 bits (286), Expect = 2e-26
Identities = 70/209 (33%), Positives = 112/209 (53%), Gaps = 1/209 (0%)
Frame = -2
Query: 685 LLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK 506
LLG KM+ EDI + +ML GV+T + + + LY +A+ K Q +L E+ Q
Sbjct: 305 LLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAA-RHQA 363
Query: 505 IMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDAS 326
D+ + + P L+A IKETLRL P L R L ++ L Y IP TL+ ++
Sbjct: 364 QGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALG 423
Query: 325 LKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQK 146
+ + + D F P RWL D N + F ++ FG+G R+CLG+ IAE M++ + +L+
Sbjct: 424 REPTFFFDPENFDPTRWLSKDKNITY-FRNLGFGWGVRQCLGRRIAELEMTIFLINMLEN 482
Query: 145 YKLE-YHYGDLEPTRSFIARPKRALKLRF 62
+++E H D+ T + I P++ + F
Sbjct: 483 FRVEIQHLSDVGTTFNLILMPEKPISFTF 511
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 287 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 346
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 347 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 405
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 406 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 465
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 466 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 493
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 287 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 346
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 347 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 405
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 406 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 465
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 466 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 493
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 287 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 346
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 347 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 405
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 406 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 465
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 466 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 493
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 288 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 347
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 348 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 406
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 407 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 466
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 467 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 494
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 273 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 332
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 333 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 391
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 392 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 451
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 452 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 479
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 288 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 347
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 348 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 406
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 407 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 466
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 467 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 494
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 287 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 346
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 347 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 405
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 406 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 465
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 466 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 493
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 288 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 347
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 348 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 406
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 407 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 466
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 467 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 494
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 287 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 346
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 347 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 405
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 406 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 465
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 466 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 493
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 273 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 332
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 333 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 391
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 392 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 451
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 452 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 479
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 288 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 347
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 348 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 406
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 407 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 466
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 467 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 494
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 287 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 346
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 347 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 405
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 406 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 465
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 466 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 493
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 273 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVR 332
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 333 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 391
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 392 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 451
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 452 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 479
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 98.7 bits (235), Expect = 2e-20
Identities = 63/213 (29%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T TS S+ LY +A Y + Q +E++
Sbjct: 287 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCIALYPEHQHRCREEVR 346
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 347 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 405
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 406 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 465
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 466 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 493
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 97.1 bits (231), Expect = 7e-20
Identities = 62/213 (29%), Positives = 106/213 (49%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A K++ D+ + + G +T T S+ LY +A Y + Q +E++
Sbjct: 287 DILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTGGISWFLYCMALYPEHQHRCREEVR 346
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNIT-LDKYNIPRGTLI 350
E +Q + + T YL CIKE+ RL PP+P + R L K +T +D ++P G+LI
Sbjct: 347 EILGDQDFFQWDDLGKMT-YLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLI 405
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
M + + D F R+ ++++ H FA +PF G R C+GQ A + M +
Sbjct: 406 SMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKV 465
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
+T L +++ L+P+R I P+ L+
Sbjct: 466 VTAMCLLRFEF-----SLDPSRLPIKMPQLVLR 493
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 96.3 bits (229), Expect = 1e-19
Identities = 60/213 (28%), Positives = 104/213 (48%), Gaps = 2/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL++A + + D+ + + G +T +S+ S++LY LAKY + Q+ EI+
Sbjct: 286 DILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIR 345
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
E + + + Q PY CIKE LRL P+ ++R+L K IT D ++P G +
Sbjct: 346 ELLGDGSSITWEHL-SQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITV 404
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++ ++D F P R+ + +S + H +A IPF G R C+GQ+ A +
Sbjct: 405 FINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKV 464
Query: 169 LTVKLLQKYKL-EYHYGDLEPTRSFIARPKRAL 74
L ++KL H +P R + + K +
Sbjct: 465 AVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGI 497
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 96.3 bits (229), Expect = 1e-19
Identities = 60/213 (28%), Positives = 104/213 (48%), Gaps = 2/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL++A + + D+ + + G +T +S+ S++LY LAKY + Q+ EI+
Sbjct: 286 DILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIR 345
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
E + + + Q PY CIKE LRL P+ ++R+L K IT D ++P G +
Sbjct: 346 ELLGDGSSITWEHL-SQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITV 404
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++ ++D F P R+ + +S + H +A IPF G R C+GQ+ A +
Sbjct: 405 FINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKV 464
Query: 169 LTVKLLQKYKL-EYHYGDLEPTRSFIARPKRAL 74
L ++KL H +P R + + K +
Sbjct: 465 AVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGI 497
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 96.3 bits (229), Expect = 1e-19
Identities = 60/213 (28%), Positives = 104/213 (48%), Gaps = 2/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL++A + + D+ + + G +T +S+ S++LY LAKY + Q+ EI+
Sbjct: 286 DILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIR 345
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
E + + + Q PY CIKE LRL P+ ++R+L K IT D ++P G +
Sbjct: 346 ELLGDGSSITWEHL-SQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITV 404
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++ ++D F P R+ + +S + H +A IPF G R C+GQ+ A +
Sbjct: 405 FINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKV 464
Query: 169 LTVKLLQKYKL-EYHYGDLEPTRSFIARPKRAL 74
L ++KL H +P R + + K +
Sbjct: 465 AVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGI 497
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 96.3 bits (229), Expect = 1e-19
Identities = 60/213 (28%), Positives = 104/213 (48%), Gaps = 2/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL++A + + D+ + + G +T +S+ S++LY LAKY + Q+ EI+
Sbjct: 286 DILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIR 345
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
E + + + Q PY CIKE LRL P+ ++R+L K IT D ++P G +
Sbjct: 346 ELLGDGSSITWEHL-SQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITV 404
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++ ++D F P R+ + +S + H +A IPF G R C+GQ+ A +
Sbjct: 405 FINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKV 464
Query: 169 LTVKLLQKYKL-EYHYGDLEPTRSFIARPKRAL 74
L ++KL H +P R + + K +
Sbjct: 465 AVALTLLRFKLAPDHSRPPQPVRQVVLKSKNGI 497
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 92.7 bits (220), Expect = 1e-18
Identities = 57/205 (27%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
P+L C+KE+LRL PP+PV++R + ++I L D IP+G + ++S
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L +++
Sbjct: 431 PAMWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 92.7 bits (220), Expect = 1e-18
Identities = 57/205 (27%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
P+L C+KE+LRL PP+PV++R + ++I L D IP+G + ++S
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L +++
Sbjct: 431 PAMWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/205 (27%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
P+L C+KE+LRL PP+PV++R + ++I L D IP+G + ++S
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L +++
Sbjct: 431 PAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/205 (27%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
P+L C+KE+LRL PP+PV++R + ++I L D IP+G + ++S
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L +++
Sbjct: 431 PAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/205 (27%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
P+L C+KE+LRL PP+PV++R + ++I L D IP+G + ++S
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L +++
Sbjct: 431 PAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/205 (27%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
P+L C+KE+LRL PP+PV++R + ++I L D IP+G + ++S
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L +++
Sbjct: 431 PAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/205 (27%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
P+L C+KE+LRL PP+PV++R + ++I L D IP+G + ++S
Sbjct: 371 EWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L +++
Sbjct: 431 PAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 91.5 bits (217), Expect = 3e-18
Identities = 58/205 (28%), Positives = 103/205 (50%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
Q P+L CIKE+LRL PP+P ++R ++I L D IP+G + ++S
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L +++
Sbjct: 431 PAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 91.5 bits (217), Expect = 3e-18
Identities = 64/208 (30%), Positives = 107/208 (51%), Gaps = 5/208 (2%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
++++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ +++
Sbjct: 311 KELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
Q P+L CIKE+LRL PP+PV++R ++ L D IP+G + +++
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMS-LLTVKLLQKY 143
+ + D + P R+ + + E A IPF G R C+GQ A M +L + LL
Sbjct: 431 PTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFR 490
Query: 142 KLEYHYGDLEPTR--SFIARPKRALKLR 65
L H +EP R I R + L LR
Sbjct: 491 ILPTH---IEPRRKPELILRAEGGLWLR 515
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 91.1 bits (216), Expect = 5e-18
Identities = 57/205 (27%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
++++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ +++
Sbjct: 311 KELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
Q P+L CIKE+LRL PP+PV++R ++ L D IP+G + +++
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + + E A IPF G R C+GQ A M ++ L ++
Sbjct: 431 PTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + I R + L LR
Sbjct: 491 ILPTHTEPRRKPELILRAEGGLWLR 515
>U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase
cytochrome P450 protein.
Length = 509
Score = 90.6 bits (215), Expect = 6e-18
Identities = 55/191 (28%), Positives = 106/191 (55%), Gaps = 2/191 (1%)
Frame = -2
Query: 700 LINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQEN 521
L++A + +++A +++ +LL G +T +++++++ ++LA+ + QK Y E Q+
Sbjct: 291 LLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLE-QKT 349
Query: 520 FPEQKIMDLTKIR-EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIM 344
+ + LT + + L CIKETLRL PPI ++ R+ T+ Y IP G + +
Sbjct: 350 VCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCV 409
Query: 343 S-TQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLL 167
S T + LK+S + + F P+R+L+ + FA +PFG G +C+G+N A + +
Sbjct: 410 SPTVNQRLKDS-WVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTI 468
Query: 166 TVKLLQKYKLE 134
+L+ Y+ +
Sbjct: 469 WSTMLRLYEFD 479
>D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase
protein.
Length = 509
Score = 90.6 bits (215), Expect = 6e-18
Identities = 55/191 (28%), Positives = 106/191 (55%), Gaps = 2/191 (1%)
Frame = -2
Query: 700 LINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQEN 521
L++A + +++A +++ +LL G +T +++++++ ++LA+ + QK Y E Q+
Sbjct: 291 LLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLE-QKT 349
Query: 520 FPEQKIMDLTKIR-EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIM 344
+ + LT + + L CIKETLRL PPI ++ R+ T+ Y IP G + +
Sbjct: 350 VCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCV 409
Query: 343 S-TQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLL 167
S T + LK+S + + F P+R+L+ + FA +PFG G +C+G+N A + +
Sbjct: 410 SPTVNQRLKDS-WVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTI 468
Query: 166 TVKLLQKYKLE 134
+L+ Y+ +
Sbjct: 469 WSTMLRLYEFD 479
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 90.6 bits (215), Expect = 6e-18
Identities = 51/176 (28%), Positives = 88/176 (50%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTS--FLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V +++I T+ST+ F++Y LA + Q+ L +EI P + + +
Sbjct: 182 DLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL- 240
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P + +TR+ K+I ++ IP+G +++ + +
Sbjct: 241 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 300
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
FCPER+ K + + L+ IPFG G R C+G A T + L ++ LQ + +
Sbjct: 301 PEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 356
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 90.6 bits (215), Expect = 6e-18
Identities = 51/176 (28%), Positives = 88/176 (50%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTS--FLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V +++I T+ST+ F++Y LA + Q+ L +EI P + + +
Sbjct: 292 DLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL- 350
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P + +TR+ K+I ++ IP+G +++ + +
Sbjct: 351 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
FCPER+ K + + L+ IPFG G R C+G A T + L ++ LQ + +
Sbjct: 411 PEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 466
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 90.6 bits (215), Expect = 6e-18
Identities = 51/176 (28%), Positives = 88/176 (50%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTS--FLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V +++I T+ST+ F++Y LA + Q+ L +EI P + + +
Sbjct: 292 DLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL- 350
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P + +TR+ K+I ++ IP+G +++ + +
Sbjct: 351 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
FCPER+ K + + L+ IPFG G R C+G A T + L ++ LQ + +
Sbjct: 411 PEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 466
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 90.6 bits (215), Expect = 6e-18
Identities = 51/176 (28%), Positives = 88/176 (50%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTS--FLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V +++I T+ST+ F++Y LA + Q+ L +EI P + + +
Sbjct: 292 DLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL- 350
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P + +TR+ K+I ++ IP+G +++ + +
Sbjct: 351 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
FCPER+ K + + L+ IPFG G R C+G A T + L ++ LQ + +
Sbjct: 411 PEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 466
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 90.6 bits (215), Expect = 6e-18
Identities = 51/176 (28%), Positives = 88/176 (50%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTS--FLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V +++I T+ST+ F++Y LA + Q+ L +EI P + + +
Sbjct: 292 DLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL- 350
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P + +TR+ K+I ++ IP+G +++ + +
Sbjct: 351 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
FCPER+ K + + L+ IPFG G R C+G A T + L ++ LQ + +
Sbjct: 411 PEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 466
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 90.6 bits (215), Expect = 6e-18
Identities = 54/181 (29%), Positives = 95/181 (52%), Gaps = 2/181 (1%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
Q P+L CIKE+LRL PP+P ++R ++I L D IP+G + ++S
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L +++
Sbjct: 431 PAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFR 490
Query: 139 L 137
+
Sbjct: 491 V 491
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 90.6 bits (215), Expect = 6e-18
Identities = 51/176 (28%), Positives = 88/176 (50%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTS--FLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V +++I T+ST+ F++Y LA + Q+ L +EI P + + +
Sbjct: 292 DLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL- 350
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P + +TR+ K+I ++ IP+G +++ + +
Sbjct: 351 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
FCPER+ K + + L+ IPFG G R C+G A T + L ++ LQ + +
Sbjct: 411 PEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 466
>AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein.
Length = 509
Score = 90.6 bits (215), Expect = 6e-18
Identities = 55/191 (28%), Positives = 106/191 (55%), Gaps = 2/191 (1%)
Frame = -2
Query: 700 LINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQEN 521
L++A + +++A +++ +LL G +T +++++++ ++LA+ + QK Y E Q+
Sbjct: 291 LLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLE-QKT 349
Query: 520 FPEQKIMDLTKIR-EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIM 344
+ + LT + + L CIKETLRL PPI ++ R+ T+ Y IP G + +
Sbjct: 350 VCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCV 409
Query: 343 S-TQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLL 167
S T + LK+S + + F P+R+L+ + FA +PFG G +C+G+N A + +
Sbjct: 410 SPTVNQRLKDS-WVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTI 468
Query: 166 TVKLLQKYKLE 134
+L+ Y+ +
Sbjct: 469 WSTMLRLYEFD 479
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 90.2 bits (214), Expect = 8e-18
Identities = 56/205 (27%), Positives = 104/205 (50%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASVLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
P+L C+KE+LR+ PP+PV++R + ++I L D IP+G + ++S
Sbjct: 371 EWDDLAHLPFLTMCMKESLRVHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L +++
Sbjct: 431 PAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 90.2 bits (214), Expect = 8e-18
Identities = 67/226 (29%), Positives = 108/226 (47%), Gaps = 1/226 (0%)
Frame = -2
Query: 736 KEIEEQYPNSNILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQK 557
+E+ P I A LL + +++ E I M++ V+T L+ LA+
Sbjct: 276 QELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPD 335
Query: 556 AQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDK 377
Q+IL KE K + P L+A +KETLRL P L R++ ++ L
Sbjct: 336 VQQILRKESLAAAASISEHP-QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQN 394
Query: 376 YNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQ 197
Y+IP GTL+ + + + + P+RWL + +L +PFG+G R+CLG+
Sbjct: 395 YHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRGSGRNLH-HVPFGFGMRQCLGR 453
Query: 196 NIAETMMSLLTVKLLQKYKLE-YHYGDLEPTRSFIARPKRALKLRF 62
+AE M LL +L+++ +E D++ SFI RP + L F
Sbjct: 454 RLAEAEMLLLLHHVLKRFLVETLTQEDIKMVYSFILRPGTSPLLTF 499
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 90.2 bits (214), Expect = 8e-18
Identities = 58/205 (28%), Positives = 102/205 (49%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
Q P+L CIKE+LRL PP+P ++R ++I L D IP+G + ++S
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L ++
Sbjct: 431 PAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family
51, subfamily A, polypeptide 1 protein.
Length = 509
Score = 90.2 bits (214), Expect = 8e-18
Identities = 54/191 (28%), Positives = 106/191 (55%), Gaps = 2/191 (1%)
Frame = -2
Query: 700 LINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQEN 521
L++A + +++A +++ +LL G +T +++++++ ++LA+ + QK Y E Q+
Sbjct: 291 LLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLE-QKT 349
Query: 520 FPEQKIMDLTKIR-EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIM 344
+ + LT + + L CIKETLRL PP+ ++ R+ T+ Y IP G + +
Sbjct: 350 VCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPVMIMMRMARTPQTVAGYTIPPGHQVCV 409
Query: 343 S-TQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLL 167
S T + LK+S + + F P+R+L+ + FA +PFG G +C+G+N A + +
Sbjct: 410 SPTVNQRLKDS-WVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTI 468
Query: 166 TVKLLQKYKLE 134
+L+ Y+ +
Sbjct: 469 WSTMLRLYEFD 479
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 90.2 bits (214), Expect = 8e-18
Identities = 58/205 (28%), Positives = 102/205 (49%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
Q P+L CIKE+LRL PP+P ++R ++I L D IP+G + ++S
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L ++
Sbjct: 431 PAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 90.2 bits (214), Expect = 8e-18
Identities = 58/205 (28%), Positives = 102/205 (49%), Gaps = 2/205 (0%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
+K++ EDI + G +T S S++LY+LAK+ + Q+ +E+QE +++ ++
Sbjct: 311 KKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEI 370
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
Q P+L CIKE+LRL PP+P ++R ++I L D IP+G + ++S
Sbjct: 371 EWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHN 430
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D + P R+ + E A IPF G R C+GQ A M ++ L ++
Sbjct: 431 PAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFR 490
Query: 139 LEYHYGDLEPTRSFIARPKRALKLR 65
+ + + + R + L LR
Sbjct: 491 VLPDHTEPRRKPELVLRAEGGLWLR 515
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 89.8 bits (213), Expect = 1e-17
Identities = 68/229 (29%), Positives = 106/229 (46%), Gaps = 4/229 (1%)
Frame = -2
Query: 736 KEIEEQYPNSNILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQK 557
+E+ P I A LL +++P+ I M++ V+T L+ LA+
Sbjct: 276 QELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPN 335
Query: 556 AQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDK 377
Q+ L +E K + P L+A +KETLRL P L R++ ++ L
Sbjct: 336 VQQALRQESLAAAASISEHP-QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQN 394
Query: 376 YNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK---SDSNEYHLFASIPFGYGARKC 206
Y+IP GTL+ + + + + P+RWL S N YH +PFG+G R+C
Sbjct: 395 YHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYH----VPFGFGMRQC 450
Query: 205 LGQNIAETMMSLLTVKLLQKYKLE-YHYGDLEPTRSFIARPKRALKLRF 62
LG+ +AE M LL +L+ ++E D++ SFI RP L F
Sbjct: 451 LGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMFPLLTF 499
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 89.8 bits (213), Expect = 1e-17
Identities = 68/229 (29%), Positives = 105/229 (45%), Gaps = 4/229 (1%)
Frame = -2
Query: 736 KEIEEQYPNSNILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQK 557
+E+ P I A LL +++P+ I M++ V+T L+ LA+
Sbjct: 276 QELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPN 335
Query: 556 AQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDK 377
Q+ L +E K + P L+A +KETLRL P L R+ ++ L
Sbjct: 336 VQQALRQESLAAAASISEHP-QKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQN 394
Query: 376 YNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK---SDSNEYHLFASIPFGYGARKC 206
Y+IP GTL+ + + + + P+RWL S N YH +PFG+G R+C
Sbjct: 395 YHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYH----VPFGFGMRQC 450
Query: 205 LGQNIAETMMSLLTVKLLQKYKLE-YHYGDLEPTRSFIARPKRALKLRF 62
LG+ +AE M LL +L+ ++E D++ SFI RP L F
Sbjct: 451 LGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMCPLLTF 499
>U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha
demethylase protein.
Length = 503
Score = 89.4 bits (212), Expect = 1e-17
Identities = 54/191 (28%), Positives = 106/191 (55%), Gaps = 2/191 (1%)
Frame = -2
Query: 700 LINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQEN 521
L++A + +++A +++ +LL G +T +++++++ ++LA+ + QK Y E Q+
Sbjct: 285 LLDATYKDGRPLTDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLE-QKT 343
Query: 520 FPEQKIMDLTKIR-EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIM 344
+ + LT + + L CI+ETLRL PPI ++ R+ T+ Y IP G + +
Sbjct: 344 VCGENLPPLTYDQLKDLNLLDRCIRETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCV 403
Query: 343 S-TQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLL 167
S T + LK+S + + F P+R+L+ + FA +PFG G +C+G+N A + +
Sbjct: 404 SPTVNQRLKDS-WVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQIKTI 462
Query: 166 TVKLLQKYKLE 134
+L+ Y+ +
Sbjct: 463 WSTMLRLYEFD 473
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 89.0 bits (211), Expect = 2e-17
Identities = 68/229 (29%), Positives = 105/229 (45%), Gaps = 4/229 (1%)
Frame = -2
Query: 736 KEIEEQYPNSNILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQK 557
+E+ P I A LL +++P+ I M++ V+T L+ LA+
Sbjct: 276 QELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPN 335
Query: 556 AQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDK 377
Q+ L +E K + P L+A +KETLRL P L R+ ++ L
Sbjct: 336 VQQALRQESLAAAASISEHP-QKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQN 394
Query: 376 YNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK---SDSNEYHLFASIPFGYGARKC 206
Y+IP GTL+ + + + + P+RWL S N YH +PFG+G R+C
Sbjct: 395 YHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYH----VPFGFGMRQC 450
Query: 205 LGQNIAETMMSLLTVKLLQKYKLE-YHYGDLEPTRSFIARPKRALKLRF 62
LG+ +AE M LL +L+ ++E D++ SFI RP L F
Sbjct: 451 LGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMFPLLTF 499
>BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein.
Length = 574
Score = 89.0 bits (211), Expect = 2e-17
Identities = 68/229 (29%), Positives = 105/229 (45%), Gaps = 4/229 (1%)
Frame = -2
Query: 736 KEIEEQYPNSNILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQK 557
+E+ P I A LL +++P+ I M++ V+T L+ LA+
Sbjct: 347 QELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPN 406
Query: 556 AQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDK 377
Q+ L +E K + P L+A +KETLRL P L R+ ++ L
Sbjct: 407 VQQALRQESLAAAASISEHP-QKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQN 465
Query: 376 YNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK---SDSNEYHLFASIPFGYGARKC 206
Y+IP GTL+ + + + + P+RWL S N YH +PFG+G R+C
Sbjct: 466 YHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYH----VPFGFGMRQC 521
Query: 205 LGQNIAETMMSLLTVKLLQKYKLE-YHYGDLEPTRSFIARPKRALKLRF 62
LG+ +AE M LL +L+ ++E D++ SFI RP L F
Sbjct: 522 LGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMFPLLTF 570
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 87.8 bits (208), Expect = 4e-17
Identities = 66/226 (29%), Positives = 107/226 (47%), Gaps = 1/226 (0%)
Frame = -2
Query: 736 KEIEEQYPNSNILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQK 557
+E+ P I A LL + +++ E I M++ V+T L+ LA+
Sbjct: 276 QELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPD 335
Query: 556 AQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDK 377
Q+IL +E K + P L+A +KETLRL P L R++ ++ L
Sbjct: 336 VQQILRQESLAAAASISEHP-QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQN 394
Query: 376 YNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQ 197
Y+IP GTL+ + + + + P+RWL + + F +PFG+G R+CLG+
Sbjct: 395 YHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGR 453
Query: 196 NIAETMMSLLTVKLLQKYKLE-YHYGDLEPTRSFIARPKRALKLRF 62
+AE M LL +L+ + +E D++ SFI RP + L F
Sbjct: 454 RLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSFILRPGTSPLLTF 499
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 87.8 bits (208), Expect = 4e-17
Identities = 66/226 (29%), Positives = 107/226 (47%), Gaps = 1/226 (0%)
Frame = -2
Query: 736 KEIEEQYPNSNILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQK 557
+E+ P I A LL + +++ E I M++ V+T L+ LA+
Sbjct: 276 QELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPD 335
Query: 556 AQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDK 377
Q+IL +E K + P L+A +KETLRL P L R++ ++ L
Sbjct: 336 VQQILRQESLAAAASISEHP-QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQN 394
Query: 376 YNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQ 197
Y+IP GTL+ + + + + P+RWL + + F +PFG+G R+CLG+
Sbjct: 395 YHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGR 453
Query: 196 NIAETMMSLLTVKLLQKYKLE-YHYGDLEPTRSFIARPKRALKLRF 62
+AE M LL +L+ + +E D++ SFI RP + L F
Sbjct: 454 RLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSFILRPGTSPLLTF 499
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 87.8 bits (208), Expect = 4e-17
Identities = 67/229 (29%), Positives = 105/229 (45%), Gaps = 4/229 (1%)
Frame = -2
Query: 736 KEIEEQYPNSNILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQK 557
+E+ P I A LL +++P+ I M++ ++T L+ LA+
Sbjct: 276 QELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSMDTTVFPLLMTLFELARNPN 335
Query: 556 AQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDK 377
Q+ L +E K + P L+A +KETLRL P L R+ ++ L
Sbjct: 336 VQQALRQESLAAAASISEHP-QKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQN 394
Query: 376 YNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK---SDSNEYHLFASIPFGYGARKC 206
Y+IP GTL+ + + + + P+RWL S N YH +PFG+G R+C
Sbjct: 395 YHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYH----VPFGFGMRQC 450
Query: 205 LGQNIAETMMSLLTVKLLQKYKLE-YHYGDLEPTRSFIARPKRALKLRF 62
LG+ +AE M LL +L+ ++E D++ SFI RP L F
Sbjct: 451 LGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMFPLLTF 499
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 87.8 bits (208), Expect = 4e-17
Identities = 59/217 (27%), Positives = 107/217 (49%), Gaps = 6/217 (2%)
Frame = -2
Query: 697 INAMLLGQEK----MNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEI 530
I+ +LL ++K ++ EDI + G +T S S++LY LA++ + Q+ +E+
Sbjct: 299 IDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEV 358
Query: 529 QENFPEQKIMDLT-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGT 356
QE +++ ++ Q P+L C+KE+LRL PPIP R +++ L D IP+G
Sbjct: 359 QELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGN 418
Query: 355 LIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMM 176
+ ++ S + D + P R+ ++ + A IPF G R C+GQ A M
Sbjct: 419 VCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEM 478
Query: 175 SLLTVKLLQKYKLEYHYGDLEPTRSFIARPKRALKLR 65
++ L ++++ + + T + R + L LR
Sbjct: 479 KVVLALTLLRFRILPDHREPRRTPEIVLRAEDGLWLR 515
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 87.4 bits (207), Expect = 6e-17
Identities = 49/168 (29%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
Frame = -2
Query: 643 VIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYL 464
+I D+ + G +T T+S + L Y++ Q+ +++EI+ + LT + Q PY
Sbjct: 345 IIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTD-KAQMPYT 403
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
+A I E RLT +P+ + + +N L Y IP+GTLI+ + + ++ F
Sbjct: 404 EATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFY 463
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKY 143
P R+L IPFG G R C+G+ +A+ + L+ V L+Q +
Sbjct: 464 PNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 87.4 bits (207), Expect = 6e-17
Identities = 50/176 (28%), Positives = 87/176 (49%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTS--FLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V +++I T+ST+ F++Y LA + Q+ L +EI + + +
Sbjct: 292 DLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLANKAPVTYDAL- 350
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P + +TR+ K+I ++ IP+G +++ + +
Sbjct: 351 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
FCPER+ K + + L+ IPFG G R C+G A T + L ++ LQ + +
Sbjct: 411 PEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 466
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 87.4 bits (207), Expect = 6e-17
Identities = 49/168 (29%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
Frame = -2
Query: 643 VIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYL 464
+I D+ + G +T T+S + L Y++ Q+ +++EI+ + LT + Q PY
Sbjct: 345 IIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTD-KAQMPYT 403
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
+A I E RLT +P+ + + +N L Y IP+GTLI+ + + ++ F
Sbjct: 404 EATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFY 463
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKY 143
P R+L IPFG G R C+G+ +A+ + L+ V L+Q +
Sbjct: 464 PNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 86.2 bits (204), Expect = 1e-16
Identities = 51/177 (28%), Positives = 88/177 (49%), Gaps = 3/177 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTS--FLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V +++I T+ST+ F++Y LA + Q+ L +EI P + + +
Sbjct: 292 DLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL- 350
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P + +TR+ K+I ++ IP+G +++ + +
Sbjct: 351 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 410
Query: 301 ANTFCPE-RWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
FCPE R+ K + + L+ IPFG G R C+G A T + L ++ LQ + +
Sbjct: 411 PEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 467
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 86.2 bits (204), Expect = 1e-16
Identities = 51/177 (28%), Positives = 88/177 (49%), Gaps = 3/177 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTS--FLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V +++I T+ST+ F++Y LA + Q+ L +EI P + + +
Sbjct: 292 DLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL- 350
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P + +TR+ K+I ++ IP+G +++ + +
Sbjct: 351 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 410
Query: 301 ANTFCPE-RWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
FCPE R+ K + + L+ IPFG G R C+G A T + L ++ LQ + +
Sbjct: 411 PEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 467
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 85.4 bits (202), Expect = 2e-16
Identities = 51/191 (26%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 293 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 352
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 353 SLLGDGASITWNHL-DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMV 411
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++S + + F P R+ + H F +PF G+R C+G+ A + +
Sbjct: 412 LLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNELKV 469
Query: 169 LTVKLLQKYKL 137
T L +++L
Sbjct: 470 ATALTLLRFEL 480
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 85.4 bits (202), Expect = 2e-16
Identities = 51/191 (26%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 293 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 352
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 353 SLLGDGASITWNHL-DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMV 411
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++S + + F P R+ + H F +PF G+R C+G+ A + +
Sbjct: 412 LLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNELKV 469
Query: 169 LTVKLLQKYKL 137
T L +++L
Sbjct: 470 ATALTLLRFEL 480
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 85.0 bits (201), Expect = 3e-16
Identities = 53/198 (26%), Positives = 99/198 (50%), Gaps = 2/198 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQ 476
D+ + + LL G +T+ +S S++LY LA + Q+ +E++ + + ++ E
Sbjct: 305 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 364
Query: 475 TPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLKESNYDDA 299
+ Y CIKET RL P +P ++R L K +T D +P G +++S + + +
Sbjct: 365 S-YTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 423
Query: 298 NTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYH-YG 122
F P R+ + +S++ H +A +PF G+R C+GQ A + + +L +++
Sbjct: 424 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 483
Query: 121 DLEPTRSFIARPKRALKL 68
L FI +PK + L
Sbjct: 484 PLTFPNHFILKPKNGMYL 501
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 85.0 bits (201), Expect = 3e-16
Identities = 53/198 (26%), Positives = 99/198 (50%), Gaps = 2/198 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQ 476
D+ + + LL G +T+ +S S++LY LA + Q+ +E++ + + ++ E
Sbjct: 305 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 364
Query: 475 TPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLKESNYDDA 299
+ Y CIKET RL P +P ++R L K +T D +P G +++S + + +
Sbjct: 365 S-YTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 423
Query: 298 NTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYH-YG 122
F P R+ + +S++ H +A +PF G+R C+GQ A + + +L +++
Sbjct: 424 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 483
Query: 121 DLEPTRSFIARPKRALKL 68
L FI +PK + L
Sbjct: 484 PLTFPNHFILKPKNGMYL 501
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 85.0 bits (201), Expect = 3e-16
Identities = 53/198 (26%), Positives = 99/198 (50%), Gaps = 2/198 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQ 476
D+ + + LL G +T+ +S S++LY LA + Q+ +E++ + + ++ E
Sbjct: 305 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 364
Query: 475 TPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLKESNYDDA 299
+ Y CIKET RL P +P ++R L K +T D +P G +++S + + +
Sbjct: 365 S-YTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 423
Query: 298 NTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYH-YG 122
F P R+ + +S++ H +A +PF G+R C+GQ A + + +L +++
Sbjct: 424 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 483
Query: 121 DLEPTRSFIARPKRALKL 68
L FI +PK + L
Sbjct: 484 PLTFPNHFILKPKNGMYL 501
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 85.0 bits (201), Expect = 3e-16
Identities = 53/198 (26%), Positives = 99/198 (50%), Gaps = 2/198 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQ 476
D+ + + LL G +T+ +S S++LY LA + Q+ +E++ + + ++ E
Sbjct: 305 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 364
Query: 475 TPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLKESNYDDA 299
+ Y CIKET RL P +P ++R L K +T D +P G +++S + + +
Sbjct: 365 S-YTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 423
Query: 298 NTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYH-YG 122
F P R+ + +S++ H +A +PF G+R C+GQ A + + +L +++
Sbjct: 424 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 483
Query: 121 DLEPTRSFIARPKRALKL 68
L FI +PK + L
Sbjct: 484 PLTFPNHFILKPKNGMYL 501
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 85.0 bits (201), Expect = 3e-16
Identities = 51/178 (28%), Positives = 90/178 (50%), Gaps = 5/178 (2%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQEN-----FPEQ 509
E+++ + + ++L G T S+ + L+ YL Y + + +E++ +
Sbjct: 214 ERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD 273
Query: 508 KIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDA 329
+D+ +I EQ Y+ IKETLRL PP+P R+ K L+ Y IP+G +I S D
Sbjct: 274 NKLDM-EILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDT 332
Query: 328 SLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKL 155
+ + F P+R++ + F+ IPFG G R C+G+ A+ ++ + TV+L
Sbjct: 333 HDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVEL 390
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 85.0 bits (201), Expect = 3e-16
Identities = 51/178 (28%), Positives = 90/178 (50%), Gaps = 5/178 (2%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQEN-----FPEQ 509
E+++ + + ++L G T S+ + L+ YL Y + + +E++ +
Sbjct: 283 ERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD 342
Query: 508 KIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDA 329
+D+ +I EQ Y+ IKETLRL PP+P R+ K L+ Y IP+G +I S D
Sbjct: 343 NKLDM-EILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDT 401
Query: 328 SLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKL 155
+ + F P+R++ + F+ IPFG G R C+G+ A+ ++ + TV+L
Sbjct: 402 HDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVEL 459
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 85.0 bits (201), Expect = 3e-16
Identities = 53/198 (26%), Positives = 99/198 (50%), Gaps = 2/198 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQ 476
D+ + + LL G +T+ +S S++LY LA + Q+ +E++ + + ++ E
Sbjct: 304 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 363
Query: 475 TPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLKESNYDDA 299
+ Y CIKET RL P +P ++R L K +T D +P G +++S + + +
Sbjct: 364 S-YTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 422
Query: 298 NTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYH-YG 122
F P R+ + +S++ H +A +PF G+R C+GQ A + + +L +++
Sbjct: 423 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 482
Query: 121 DLEPTRSFIARPKRALKL 68
L FI +PK + L
Sbjct: 483 PLTFPNHFILKPKNGMYL 500
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 85.0 bits (201), Expect = 3e-16
Identities = 53/198 (26%), Positives = 99/198 (50%), Gaps = 2/198 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQ 476
D+ + + LL G +T+ +S S++LY LA + Q+ +E++ + + ++ E
Sbjct: 305 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 364
Query: 475 TPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLKESNYDDA 299
+ Y CIKET RL P +P ++R L K +T D +P G +++S + + +
Sbjct: 365 S-YTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 423
Query: 298 NTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYH-YG 122
F P R+ + +S++ H +A +PF G+R C+GQ A + + +L +++
Sbjct: 424 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 483
Query: 121 DLEPTRSFIARPKRALKL 68
L FI +PK + L
Sbjct: 484 PLTFPNHFILKPKNGMYL 501
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 85.0 bits (201), Expect = 3e-16
Identities = 53/198 (26%), Positives = 99/198 (50%), Gaps = 2/198 (1%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQ 476
D+ + + LL G +T+ +S S++LY LA + Q+ +E++ + + ++ E
Sbjct: 240 DVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEM 299
Query: 475 TPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLKESNYDDA 299
+ Y CIKET RL P +P ++R L K +T D +P G +++S + + +
Sbjct: 300 S-YTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 358
Query: 298 NTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYH-YG 122
F P R+ + +S++ H +A +PF G+R C+GQ A + + +L +++
Sbjct: 359 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 418
Query: 121 DLEPTRSFIARPKRALKL 68
L FI +PK + L
Sbjct: 419 PLTFPNHFILKPKNGMYL 436
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 85.0 bits (201), Expect = 3e-16
Identities = 51/178 (28%), Positives = 90/178 (50%), Gaps = 5/178 (2%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQEN-----FPEQ 509
E+++ + + ++L G T S+ + L+ YL Y + + +E++ +
Sbjct: 283 ERLDMQALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD 342
Query: 508 KIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDA 329
+D+ +I EQ Y+ IKETLRL PP+P R+ K L+ Y IP+G +I S D
Sbjct: 343 NKLDM-EILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDT 401
Query: 328 SLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKL 155
+ + F P+R++ + F+ IPFG G R C+G+ A+ ++ + TV+L
Sbjct: 402 HDVAEIFTNKEEFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVEL 459
>M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxylase
protein.
Length = 256
Score = 84.6 bits (200), Expect = 4e-16
Identities = 59/194 (30%), Positives = 93/194 (47%), Gaps = 4/194 (2%)
Frame = -2
Query: 736 KEIEEQYPNSNILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQK 557
+E+ P I A LL +++P+ I M++ V+ L+ LA+
Sbjct: 66 QELANSRPQQYTSIVAELLLNAELSPDAIKANCMELTAGSVDRTVFPLLMTLFELARNPN 125
Query: 556 AQKILYKEIQENFPEQKIMDLT-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD 380
Q+ L +E P I + K + P L+A +KETLRL P +L R++ ++ L
Sbjct: 126 VQQPLRQESLA--PAASISEHPQKATTELPLLRAALKETLRLYPVGLILERVVSSDLVLQ 183
Query: 379 KYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK---SDSNEYHLFASIPFGYGARK 209
Y+IP GTL+ + + + + P+RWL S N YH +PFG+G R+
Sbjct: 184 NYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIKGSGRNFYH----VPFGFGMRQ 239
Query: 208 CLGQNIAETMMSLL 167
CLG+ +AE M LL
Sbjct: 240 CLGRRLAEADMLLL 253
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 84.6 bits (200), Expect = 4e-16
Identities = 50/183 (27%), Positives = 92/183 (50%)
Frame = -2
Query: 820 LWSNTVIVWIV*LANTSWRPEQAISYKAKEIEEQYPNSNILINAMLLGQEKMNPEDIATV 641
+W + + W +T ++ +A E Q P+++ L + + Q +++ +++
Sbjct: 267 VWQDHTLAW-----DTIFKSVKACIDNRLEKYSQQPSADFLCD--IYHQNRLSKKELYAA 319
Query: 640 IMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQ 461
+ ++ L V T +S ++LY L++ + Q+ L KEIQ PE ++ +R PYL+
Sbjct: 320 VTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNM-PYLK 378
Query: 460 ACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPE 281
AC+KE++RLTP +P TR L K L +Y +P+G + Q + + T P
Sbjct: 379 ACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGIVRKYDIQATDNEPVEMLHSGTLVPS 438
Query: 280 RWL 272
R L
Sbjct: 439 REL 441
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 84.6 bits (200), Expect = 4e-16
Identities = 50/183 (27%), Positives = 92/183 (50%)
Frame = -2
Query: 820 LWSNTVIVWIV*LANTSWRPEQAISYKAKEIEEQYPNSNILINAMLLGQEKMNPEDIATV 641
+W + + W +T ++ +A E Q P+++ L + + Q +++ +++
Sbjct: 267 VWQDHTLAW-----DTIFKSVKACIDNRLEKYSQQPSADFLCD--IYHQNRLSKKELYAA 319
Query: 640 IMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQ 461
+ ++ L V T +S ++LY L++ + Q+ L KEIQ PE ++ +R PYL+
Sbjct: 320 VTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNM-PYLK 378
Query: 460 ACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPE 281
AC+KE++RLTP +P TR L K L +Y +P+G + Q + + T P
Sbjct: 379 ACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGIVRKYDIQATDNEPVEMLHSGTLVPS 438
Query: 280 RWL 272
R L
Sbjct: 439 REL 441
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 84.6 bits (200), Expect = 4e-16
Identities = 50/183 (27%), Positives = 92/183 (50%)
Frame = -2
Query: 820 LWSNTVIVWIV*LANTSWRPEQAISYKAKEIEEQYPNSNILINAMLLGQEKMNPEDIATV 641
+W + + W +T ++ +A E Q P+++ L + + Q +++ +++
Sbjct: 267 VWQDHTLAW-----DTIFKSVKACIDNRLEKYSQQPSADFLCD--IYHQNRLSKKELYAA 319
Query: 640 IMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQ 461
+ ++ L V T +S ++LY L++ + Q+ L KEIQ PE ++ +R PYL+
Sbjct: 320 VTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNM-PYLK 378
Query: 460 ACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPE 281
AC+KE++RLTP +P TR L K L +Y +P+G + Q + + T P
Sbjct: 379 ACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGIVRKYDIQATDNEPVEMLHSGTLVPS 438
Query: 280 RWL 272
R L
Sbjct: 439 REL 441
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 84.2 bits (199), Expect = 5e-16
Identities = 51/191 (26%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 293 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 352
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 353 SLLGDGASITWNHL-DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMV 411
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++S + + F P R+ + H F +PF G+R C+G+ A + +
Sbjct: 412 LLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNELKV 469
Query: 169 LTVKLLQKYKL 137
T L +++L
Sbjct: 470 ATALTLLRFEL 480
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 84.2 bits (199), Expect = 5e-16
Identities = 51/191 (26%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 293 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 352
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 353 SLLGDGASITWNHL-DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMV 411
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++S + + F P R+ + H F +PF G+R C+G+ A + +
Sbjct: 412 LLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNELKV 469
Query: 169 LTVKLLQKYKL 137
T L +++L
Sbjct: 470 ATALTLLRFEL 480
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 84.2 bits (199), Expect = 5e-16
Identities = 50/181 (27%), Positives = 95/181 (52%), Gaps = 2/181 (1%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
++++ EDI + G +T +S S++L+ LAKY + Q+ +EIQE +++ +L
Sbjct: 318 KELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEEL 377
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
Q P+ CIKE+LR PP+ +++R ++I L D IP+G + ++S
Sbjct: 378 EWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHN 437
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D+ + P R+ + + A +PF G R C+GQ+ A + ++ L +++
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFR 497
Query: 139 L 137
L
Sbjct: 498 L 498
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 84.2 bits (199), Expect = 5e-16
Identities = 50/181 (27%), Positives = 95/181 (52%), Gaps = 2/181 (1%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
++++ EDI + G +T +S S++L+ LAKY + Q+ +EIQE +++ +L
Sbjct: 318 KELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEEL 377
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
Q P+ CIKE+LR PP+ +++R ++I L D IP+G + ++S
Sbjct: 378 EWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHN 437
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D+ + P R+ + + A +PF G R C+GQ+ A + ++ L +++
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFR 497
Query: 139 L 137
L
Sbjct: 498 L 498
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 84.2 bits (199), Expect = 5e-16
Identities = 50/181 (27%), Positives = 95/181 (52%), Gaps = 2/181 (1%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
++++ EDI + G +T +S S++L+ LAKY + Q+ +EIQE +++ +L
Sbjct: 318 KELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEEL 377
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
Q P+ CIKE+LR PP+ +++R ++I L D IP+G + ++S
Sbjct: 378 EWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHN 437
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D+ + P R+ + + A +PF G R C+GQ+ A + ++ L +++
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFR 497
Query: 139 L 137
L
Sbjct: 498 L 498
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 84.2 bits (199), Expect = 5e-16
Identities = 51/191 (26%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 293 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 352
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 353 SLLGDGASITWNHL-DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMV 411
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++S + + F P R+ + H F +PF G+R C+G+ A + +
Sbjct: 412 LLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNELKV 469
Query: 169 LTVKLLQKYKL 137
T L +++L
Sbjct: 470 ATALTLLRFEL 480
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 84.2 bits (199), Expect = 5e-16
Identities = 51/191 (26%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 293 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 352
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 353 SLLGDGASITWNHL-DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMV 411
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++S + + F P R+ + H F +PF G+R C+G+ A + +
Sbjct: 412 LLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNELKV 469
Query: 169 LTVKLLQKYKL 137
T L +++L
Sbjct: 470 ATALTLLRFEL 480
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 84.2 bits (199), Expect = 5e-16
Identities = 50/181 (27%), Positives = 95/181 (52%), Gaps = 2/181 (1%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
++++ EDI + G +T +S S++L+ LAKY + Q+ +EIQE +++ +L
Sbjct: 318 KELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEEL 377
Query: 493 T-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLIIMSTQDASLK 320
Q P+ CIKE+LR PP+ +++R ++I L D IP+G + ++S
Sbjct: 378 EWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHN 437
Query: 319 ESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + D+ + P R+ + + A +PF G R C+GQ+ A + ++ L +++
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFR 497
Query: 139 L 137
L
Sbjct: 498 L 498
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 84.2 bits (199), Expect = 5e-16
Identities = 51/191 (26%), Positives = 93/191 (48%), Gaps = 1/191 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 293 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 352
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 353 SLLGDGASITWNHL-DQMPYTTMCIKEALRLFPPVPGIGRELSTPVTFPDGRSLPKGIMV 411
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++S + + F P R+ + H F +PF G+R C+G+ A + +
Sbjct: 412 LLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNELKV 469
Query: 169 LTVKLLQKYKL 137
T L +++L
Sbjct: 470 ATALTLLRFEL 480
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 83.0 bits (196), Expect = 1e-15
Identities = 50/191 (26%), Positives = 92/191 (48%), Gaps = 1/191 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 293 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 352
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 353 GLLGDGASITWNHL-DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMV 411
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++S + + F P R+ + H F +PF G+R C+G+ A + +
Sbjct: 412 LLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNQLKV 469
Query: 169 LTVKLLQKYKL 137
L +++L
Sbjct: 470 ARALTLLRFEL 480
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 83.0 bits (196), Expect = 1e-15
Identities = 56/213 (26%), Positives = 101/213 (47%), Gaps = 1/213 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 293 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 352
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 353 SLLGDGASITWNHL-DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMV 411
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++S + + F P R+ + H F +PF G+R C+G+ A + +
Sbjct: 412 LLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNQLKV 469
Query: 169 LTVKLLQKYKLEYHYGDLEPTRSFIARPKRALK 71
L +++L +PTR+ I + LK
Sbjct: 470 ARALTLLRFELL-----PDPTRTPIPMARLVLK 497
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 83.0 bits (196), Expect = 1e-15
Identities = 50/191 (26%), Positives = 92/191 (48%), Gaps = 1/191 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 293 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 352
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 353 GLLGDGASITWNHL-DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMV 411
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++S + + F P R+ + H F +PF G+R C+G+ A + +
Sbjct: 412 LLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNQLKV 469
Query: 169 LTVKLLQKYKL 137
L +++L
Sbjct: 470 ARALTLLRFEL 480
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 83.0 bits (196), Expect = 1e-15
Identities = 50/191 (26%), Positives = 92/191 (48%), Gaps = 1/191 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 293 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 352
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 353 GLLGDGASITWNHL-DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMV 411
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSL 170
++S + + F P R+ + H F +PF G+R C+G+ A + +
Sbjct: 412 LLSIYGLHHNPKVWPNLEVFDPSRFAPGSAQHSHAF--LPFSGGSRNCIGKQFAMNQLKV 469
Query: 169 LTVKLLQKYKL 137
L +++L
Sbjct: 470 ARALTLLRFEL 480
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 82.6 bits (195), Expect = 2e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHCTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 287 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 346
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 347 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 406
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 407 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 452
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 287 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 346
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 347 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 406
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 407 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 452
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 287 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 346
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 347 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 406
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 407 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 452
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 292 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 351
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 352 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 411 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 46/165 (27%), Positives = 78/165 (47%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
+ G T +S SF++Y LA + Q+ + KEI P + + Q YL +
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL-QLEYLDMVVN 361
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLRL P L R+ K++ ++ IP+G ++++ + + + F PER+ K
Sbjct: 362 ETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSK 421
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
+ + + PFG G R C+G A M L V++LQ + +
Sbjct: 422 KNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFK 466
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 292 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 351
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 352 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 411 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 292 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 351
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 352 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 411 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 464
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 256 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 315
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 316 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 375
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 376 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 421
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 287 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 346
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 347 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 406
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 407 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 452
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 292 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 351
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 352 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 411 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 292 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 351
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 352 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 411 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 46/165 (27%), Positives = 78/165 (47%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
+ G T +S SF++Y LA + Q+ + KEI P + + Q YL +
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL-QLEYLDMVVN 361
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLRL P L R+ K++ ++ IP+G ++++ + + + F PER+ K
Sbjct: 362 ETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSK 421
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
+ + + PFG G R C+G A M L V++LQ + +
Sbjct: 422 KNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFK 466
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 257 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 316
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 317 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 376
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 377 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 422
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 287 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 346
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 347 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 406
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 407 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 452
>AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 257 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 316
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 317 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 376
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 377 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 422
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 287 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 346
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 347 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 406
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 407 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 452
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 287 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 346
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 347 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 406
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 407 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 452
>AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 257 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 316
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 317 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 376
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 377 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 422
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 287 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 346
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 347 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 406
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 407 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 452
>AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens
cDNA FLJ30054 fis, clone ADRGL1000160, highly similar to
CYTOCHROME P450 XXIB (EC 1.14.99.10). ).
Length = 465
Score = 81.8 bits (193), Expect = 3e-15
Identities = 53/184 (28%), Positives = 94/184 (51%), Gaps = 3/184 (1%)
Frame = -2
Query: 679 GQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKI 503
G ++ + +D+L+ G T ++ S+ +L + + Q+ L +E+ P
Sbjct: 243 GSGQLQEGHVHMAAVDLLIGGTETTANTLSWAAVFLLHHPEIQQRLQEELDHELGPGASS 302
Query: 502 MDLT-KIREQTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDA 329
+ K R + P L A I E LRL P +P+ L + ++ Y+IP GT+II + Q A
Sbjct: 303 SRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGA 362
Query: 328 SLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQ 149
L E+ ++ + F P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ
Sbjct: 363 HLDETVWERPHEFWPDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQ 418
Query: 148 KYKL 137
+ L
Sbjct: 419 AFTL 422
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 142 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 201
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 202 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTE 260
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 261 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 316
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 219 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 278
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 279 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTE 337
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 338 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 393
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 292 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 351
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 352 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 411 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 81.8 bits (193), Expect = 3e-15
Identities = 46/165 (27%), Positives = 78/165 (47%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
+ G T +S SF++Y LA + Q+ + KEI P + + Q YL +
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL-QLEYLDMVVN 361
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLRL P L R+ K++ ++ IP+G ++++ + + + F PER+ K
Sbjct: 362 ETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSK 421
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
+ + + PFG G R C+G A M L V++LQ + +
Sbjct: 422 KNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFK 466
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 46/165 (27%), Positives = 78/165 (47%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
+ G T +S SF++Y LA + Q+ + KEI P + + Q YL +
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVL-QLEYLDMVVN 361
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLRL P L R+ K++ ++ IP+G ++++ + + + F PER+ K
Sbjct: 362 ETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSK 421
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
+ + + PFG G R C+G A M L V++LQ + +
Sbjct: 422 KNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFK 466
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 292 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 351
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 352 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 411 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 292 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 351
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 352 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 411 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 292 DLELVAQSIIFIFAGCETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 351
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 352 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 411 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 403
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 195 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 254
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 255 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 314
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 315 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 360
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 81.8 bits (193), Expect = 3e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 287 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 346
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 347 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 406
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 407 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 452
>M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein.
Length = 230
Score = 81.4 bits (192), Expect = 4e-15
Identities = 52/160 (32%), Positives = 87/160 (54%), Gaps = 1/160 (0%)
Frame = -2
Query: 613 NTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRL 434
NT++ + FLL++L Q+ Q+ L E+ ++ K R + P L A I E LRL
Sbjct: 34 NTLSWAVVFLLHHLEIQQRLQEELDHELGPGASSSRVP--YKDRARLPLLIATIAEVLRL 91
Query: 433 TPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSN 257
P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F P+R+L+ N
Sbjct: 92 RPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKN 151
Query: 256 EYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 152 S----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 187
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 81.4 bits (192), Expect = 4e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 292 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 351
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 352 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 411 PEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 81.4 bits (192), Expect = 4e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 291 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 350
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 351 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTE 409
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 410 PEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 465
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 81.4 bits (192), Expect = 4e-15
Identities = 58/217 (26%), Positives = 103/217 (47%), Gaps = 6/217 (2%)
Frame = -2
Query: 697 INAMLLGQEK----MNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEI 530
I+ +LL +++ ++ EDI + G +T S S++LY LA++ + Q+ +E+
Sbjct: 299 IDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEV 358
Query: 529 QENFPEQKIMDLT-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGT 356
QE ++ ++ Q P+L C+KE+LRL PP P ++R ++I L D IP+G
Sbjct: 359 QELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGI 418
Query: 355 LIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMM 176
++ + + D + P R+ +S A IPF G R C+GQ A M
Sbjct: 419 TCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEM 478
Query: 175 SLLTVKLLQKYKLEYHYGDLEPTRSFIARPKRALKLR 65
++ +L ++ + + I R + L LR
Sbjct: 479 KVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLR 515
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 81.4 bits (192), Expect = 4e-15
Identities = 58/217 (26%), Positives = 103/217 (47%), Gaps = 6/217 (2%)
Frame = -2
Query: 697 INAMLLGQEK----MNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEI 530
I+ +LL +++ ++ EDI + G +T S S++LY LA++ + Q+ +E+
Sbjct: 299 IDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEV 358
Query: 529 QENFPEQKIMDLT-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGT 356
QE ++ ++ Q P+L C+KE+LRL PP P ++R ++I L D IP+G
Sbjct: 359 QELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGI 418
Query: 355 LIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMM 176
++ + + D + P R+ +S A IPF G R C+GQ A M
Sbjct: 419 TCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEM 478
Query: 175 SLLTVKLLQKYKLEYHYGDLEPTRSFIARPKRALKLR 65
++ +L ++ + + I R + L LR
Sbjct: 479 KVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLR 515
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 81.4 bits (192), Expect = 4e-15
Identities = 58/217 (26%), Positives = 103/217 (47%), Gaps = 6/217 (2%)
Frame = -2
Query: 697 INAMLLGQEK----MNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEI 530
I+ +LL +++ ++ EDI + G +T S S++LY LA++ + Q+ +E+
Sbjct: 299 IDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEV 358
Query: 529 QENFPEQKIMDLT-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGT 356
QE ++ ++ Q P+L C+KE+LRL PP P ++R ++I L D IP+G
Sbjct: 359 QELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGI 418
Query: 355 LIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMM 176
++ + + D + P R+ +S A IPF G R C+GQ A M
Sbjct: 419 TCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEM 478
Query: 175 SLLTVKLLQKYKLEYHYGDLEPTRSFIARPKRALKLR 65
++ +L ++ + + I R + L LR
Sbjct: 479 KVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLR 515
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 81.4 bits (192), Expect = 4e-15
Identities = 52/170 (30%), Positives = 91/170 (53%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLFHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 81.4 bits (192), Expect = 4e-15
Identities = 58/217 (26%), Positives = 103/217 (47%), Gaps = 6/217 (2%)
Frame = -2
Query: 697 INAMLLGQEK----MNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEI 530
I+ +LL +++ ++ EDI + G +T S S++LY LA++ + Q+ +E+
Sbjct: 233 IDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEV 292
Query: 529 QENFPEQKIMDLT-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGT 356
QE ++ ++ Q P+L C+KE+LRL PP P ++R ++I L D IP+G
Sbjct: 293 QELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGI 352
Query: 355 LIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMM 176
++ + + D + P R+ +S A IPF G R C+GQ A M
Sbjct: 353 TCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEM 412
Query: 175 SLLTVKLLQKYKLEYHYGDLEPTRSFIARPKRALKLR 65
++ +L ++ + + I R + L LR
Sbjct: 413 KVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLR 449
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 81.4 bits (192), Expect = 4e-15
Identities = 58/217 (26%), Positives = 103/217 (47%), Gaps = 6/217 (2%)
Frame = -2
Query: 697 INAMLLGQEK----MNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEI 530
I+ +LL +++ ++ EDI + G +T S S++LY LA++ + Q+ +E+
Sbjct: 299 IDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEV 358
Query: 529 QENFPEQKIMDLT-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGT 356
QE ++ ++ Q P+L C+KE+LRL PP P ++R ++I L D IP+G
Sbjct: 359 QELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGI 418
Query: 355 LIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMM 176
++ + + D + P R+ +S A IPF G R C+GQ A M
Sbjct: 419 TCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEM 478
Query: 175 SLLTVKLLQKYKLEYHYGDLEPTRSFIARPKRALKLR 65
++ +L ++ + + I R + L LR
Sbjct: 479 KVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLR 515
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 81.4 bits (192), Expect = 4e-15
Identities = 58/217 (26%), Positives = 103/217 (47%), Gaps = 6/217 (2%)
Frame = -2
Query: 697 INAMLLGQEK----MNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEI 530
I+ +LL +++ ++ EDI + G +T S S++LY LA++ + Q+ +E+
Sbjct: 299 IDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEV 358
Query: 529 QENFPEQKIMDLT-KIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGT 356
QE ++ ++ Q P+L C+KE+LRL PP P ++R ++I L D IP+G
Sbjct: 359 QELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGI 418
Query: 355 LIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMM 176
++ + + D + P R+ +S A IPF G R C+GQ A M
Sbjct: 419 TCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEM 478
Query: 175 SLLTVKLLQKYKLEYHYGDLEPTRSFIARPKRALKLR 65
++ +L ++ + + I R + L LR
Sbjct: 479 KVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLR 515
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 81.0 bits (191), Expect = 5e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 292 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 351
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 352 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTE 410
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 411 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 81.0 bits (191), Expect = 5e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 293 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 352
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 353 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTE 411
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 412 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 467
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 81.0 bits (191), Expect = 5e-15
Identities = 48/176 (27%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -2
Query: 655 DIATVIMDMLLI--GVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIR 482
D+ V ++ I G T +S SF++Y LA + Q+ L +EI P + +
Sbjct: 293 DLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVL 352
Query: 481 EQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q YL + ETLRL P L R+ K++ ++ IP+G ++++ + + +
Sbjct: 353 -QMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTE 411
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K + + + PFG G R C+G A M L +++LQ + +
Sbjct: 412 PEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 467
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 80.6 bits (190), Expect = 6e-15
Identities = 51/175 (29%), Positives = 84/175 (48%), Gaps = 1/175 (0%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQ 476
++A + + G T +S SF LY LA + Q+ L KEI P + + Q
Sbjct: 294 ELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAV-VQ 352
Query: 475 TPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDAN 296
YL + ETLRL P L R K++ ++ IP+G+++++ T + +
Sbjct: 353 MEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPE 412
Query: 295 TFCPERW-LKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K DS + +++ PFG G R C+G A M L +++LQ + +
Sbjct: 413 EFRPERFSKKKDSIDPYIYT--PFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 465
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 80.6 bits (190), Expect = 6e-15
Identities = 51/175 (29%), Positives = 84/175 (48%), Gaps = 1/175 (0%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQ 476
++A + + G T +S SF LY LA + Q+ L KEI P + + Q
Sbjct: 294 ELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAV-VQ 352
Query: 475 TPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDAN 296
YL + ETLRL P L R K++ ++ IP+G+++++ T + +
Sbjct: 353 MEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPE 412
Query: 295 TFCPERW-LKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K DS + +++ PFG G R C+G A M L +++LQ + +
Sbjct: 413 EFRPERFSKKKDSIDPYIYT--PFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 465
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 80.6 bits (190), Expect = 6e-15
Identities = 51/175 (29%), Positives = 84/175 (48%), Gaps = 1/175 (0%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQ 476
++A + + G T +S SF LY LA + Q+ L KEI P + + Q
Sbjct: 294 ELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAV-VQ 352
Query: 475 TPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDAN 296
YL + ETLRL P L R K++ ++ IP+G+++++ T + +
Sbjct: 353 MEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPE 412
Query: 295 TFCPERW-LKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K DS + +++ PFG G R C+G A M L +++LQ + +
Sbjct: 413 EFRPERFSKKKDSIDPYIYT--PFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 465
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 80.2 bits (189), Expect = 9e-15
Identities = 52/180 (28%), Positives = 92/180 (51%), Gaps = 3/180 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQT--PYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ ++ P L
Sbjct: 287 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDHARLPLL 346
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 347 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 406
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYHYGDLEPT 107
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L GD P+
Sbjct: 407 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL-LSSGDALPS 461
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 80.2 bits (189), Expect = 9e-15
Identities = 46/165 (27%), Positives = 76/165 (46%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 339 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 398
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 399 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 458
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG ++ + L + +L K++ +
Sbjct: 459 EARQQHRPFTYLPFGAGPRSCLGVHLGLLEVKLTLLHVLHKFRFQ 503
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 80.2 bits (189), Expect = 9e-15
Identities = 51/170 (30%), Positives = 90/170 (52%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGTHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 80.2 bits (189), Expect = 9e-15
Identities = 51/175 (29%), Positives = 84/175 (48%), Gaps = 1/175 (0%)
Frame = -2
Query: 655 DIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQ 476
++A + + G T +S SF LY LA + Q+ L KEI P + + Q
Sbjct: 294 ELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAV-VQ 352
Query: 475 TPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDAN 296
YL + ETLRL P L R K++ ++ IP+G+++++ T + +
Sbjct: 353 MEYLDMVVNETLRLFPVAIRLERTCMKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPE 412
Query: 295 TFCPERW-LKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PER+ K DS + +++ PFG G R C+G A M L +++LQ + +
Sbjct: 413 EFRPERFSKKKDSIDPYIYT--PFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 465
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 272 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 331
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 332 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 391
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 392 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 436
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 79.8 bits (188), Expect = 1e-14
Identities = 51/160 (31%), Positives = 86/160 (53%), Gaps = 1/160 (0%)
Frame = -2
Query: 613 NTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRL 434
NT++ + FLL++ Q+ Q+ L E+ ++ K R + P L A I E LRL
Sbjct: 298 NTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVP--YKDRARLPLLNATIAEVLRL 355
Query: 433 TPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSN 257
P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F P+R+L+ N
Sbjct: 356 RPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKN 415
Query: 256 EYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
++ FG GAR CLG+ +A + ++ +LLQ + L
Sbjct: 416 S----RALAFGCGARVCLGEPLARLELFVVLTRLLQAFTL 451
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPKTFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAEDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYVLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 79.8 bits (188), Expect = 1e-14
Identities = 46/165 (27%), Positives = 75/165 (45%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ TF PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 6/186 (3%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
E ++ I T I D+ GV T TS + L +L + +K LY+EI +N + +
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 493 TKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD----KYNIPRGTLIIMSTQDAS 326
+ R + L+A I+E LRL P P+L +P +D ++ + +GT +I++
Sbjct: 345 SD-RNRLLLLEATIREVLRLRPVAPML---IPHKANVDSSIGEFAVDKGTEVIINLWALH 400
Query: 325 LKESNYDDANTFCPERWLKSDSNEY--HLFASIPFGYGARKCLGQNIAETMMSLLTVKLL 152
E + + F PER+L + + +PFG G R C+G+ +A + L+ LL
Sbjct: 401 HNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLL 460
Query: 151 QKYKLE 134
Q++ LE
Sbjct: 461 QRFDLE 466
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 6/186 (3%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
E ++ I T I D+ GV T TS + L +L + +K LY+EI +N + +
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 493 TKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD----KYNIPRGTLIIMSTQDAS 326
+ R + L+A I+E LRL P P+L +P +D ++ + +GT +I++
Sbjct: 345 SD-RNRLLLLEATIREVLRLRPVAPML---IPHKANVDSSIGEFAVDKGTEVIINLWALH 400
Query: 325 LKESNYDDANTFCPERWLKSDSNEY--HLFASIPFGYGARKCLGQNIAETMMSLLTVKLL 152
E + + F PER+L + + +PFG G R C+G+ +A + L+ LL
Sbjct: 401 HNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLL 460
Query: 151 QKYKLE 134
Q++ LE
Sbjct: 461 QRFDLE 466
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 6/186 (3%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
E ++ I T I D+ GV T TS + L +L + +K LY+EI +N + +
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 493 TKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD----KYNIPRGTLIIMSTQDAS 326
+ R + L+A I+E LRL P P+L +P +D ++ + +GT +I++
Sbjct: 345 SD-RNRLLLLEATIREVLRLRPVAPML---IPHKANVDSSIGEFAVDKGTEVIINLWALH 400
Query: 325 LKESNYDDANTFCPERWLKSDSNEY--HLFASIPFGYGARKCLGQNIAETMMSLLTVKLL 152
E + + F PER+L + + +PFG G R C+G+ +A + L+ LL
Sbjct: 401 HNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLL 460
Query: 151 QKYKLE 134
Q++ LE
Sbjct: 461 QRFDLE 466
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 6/186 (3%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
E ++ I T I D+ GV T TS + L +L + +K LY+EI +N + +
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 493 TKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD----KYNIPRGTLIIMSTQDAS 326
+ R + L+A I+E LRL P P+L +P +D ++ + +GT +I++
Sbjct: 345 SD-RNRLLLLEATIREVLRLRPVAPML---IPHKANVDSSIGEFAVDKGTEVIINLWALH 400
Query: 325 LKESNYDDANTFCPERWLKSDSNEY--HLFASIPFGYGARKCLGQNIAETMMSLLTVKLL 152
E + + F PER+L + + +PFG G R C+G+ +A + L+ LL
Sbjct: 401 HNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLL 460
Query: 151 QKYKLE 134
Q++ LE
Sbjct: 461 QRFDLE 466
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 79.4 bits (187), Expect = 1e-14
Identities = 48/174 (27%), Positives = 85/174 (48%), Gaps = 1/174 (0%)
Frame = -2
Query: 706 NILINAMLLGQEKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQ 527
+IL+ A + ++ +D+ + + G +T S S++LY LA + K Q+ +EI
Sbjct: 294 DILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIH 353
Query: 526 ENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITL-DKYNIPRGTLI 350
+ + + +Q PY CIKE LRL PP+P + R L +T D ++P+G ++
Sbjct: 354 SLLGDGASITWNHL-DQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMV 412
Query: 349 IMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIA 188
++S + + F P R+ + H F +PF G+R C+G+ A
Sbjct: 413 LLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAF--LPFSGGSRNCIGKQFA 464
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 6/186 (3%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
E ++ I T I D+ GV T TS + L +L + +K LY+EI +N + +
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 493 TKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD----KYNIPRGTLIIMSTQDAS 326
+ R + L+A I+E LRL P P+L +P +D ++ + +GT +I++
Sbjct: 345 SD-RNRLLLLEATIREVLRLRPVAPML---IPHKANVDSSIGEFAVDKGTEVIINLWALH 400
Query: 325 LKESNYDDANTFCPERWLKSDSNEY--HLFASIPFGYGARKCLGQNIAETMMSLLTVKLL 152
E + + F PER+L + + +PFG G R C+G+ +A + L+ LL
Sbjct: 401 HNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLL 460
Query: 151 QKYKLE 134
Q++ LE
Sbjct: 461 QRFDLE 466
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 6/186 (3%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
E ++ I T I D+ GV T TS + L +L + +K LY+EI +N + +
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 493 TKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD----KYNIPRGTLIIMSTQDAS 326
+ R + L+A I+E LRL P P+L +P +D ++ + +GT +I++
Sbjct: 345 SD-RNRLLLLEATIREVLRLRPVAPML---IPHKANVDSSIGEFAVDKGTEVIINLWALH 400
Query: 325 LKESNYDDANTFCPERWLKSDSNEY--HLFASIPFGYGARKCLGQNIAETMMSLLTVKLL 152
E + + F PER+L + + +PFG G R C+G+ +A + L+ LL
Sbjct: 401 HNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLL 460
Query: 151 QKYKLE 134
Q++ LE
Sbjct: 461 QRFDLE 466
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 6/186 (3%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
E ++ I T I D+ GV T TS + L +L + +K LY+EI +N + +
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 493 TKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD----KYNIPRGTLIIMSTQDAS 326
+ R + L+A I+E LRL P P+L +P +D ++ + +GT +I++
Sbjct: 345 SD-RNRLLLLEATIREVLRLRPVAPML---IPHKANVDSSIGEFAVDKGTEVIINLWALH 400
Query: 325 LKESNYDDANTFCPERWLKSDSNEY--HLFASIPFGYGARKCLGQNIAETMMSLLTVKLL 152
E + + F PER+L + + +PFG G R C+G+ +A + L+ LL
Sbjct: 401 HNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLL 460
Query: 151 QKYKLE 134
Q++ LE
Sbjct: 461 QRFDLE 466
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 6/186 (3%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
E ++ I T I D+ GV T TS + L +L + +K LY+EI +N + +
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 493 TKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD----KYNIPRGTLIIMSTQDAS 326
+ R + L+A I+E LRL P P+L +P +D ++ + +GT +I++
Sbjct: 345 SD-RNRLLLLEATIREVLRLRPVAPML---IPHKANVDSSIGEFAVDKGTEVIINLWALH 400
Query: 325 LKESNYDDANTFCPERWLKSDSNEY--HLFASIPFGYGARKCLGQNIAETMMSLLTVKLL 152
E + + F PER+L + + +PFG G R C+G+ +A + L+ LL
Sbjct: 401 HNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLL 460
Query: 151 QKYKLE 134
Q++ LE
Sbjct: 461 QRFDLE 466
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/186 (29%), Positives = 92/186 (49%), Gaps = 6/186 (3%)
Frame = -2
Query: 673 EKMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDL 494
E ++ I T I D+ GV T TS + L +L + +K LY+EI +N + +
Sbjct: 285 ELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTI 344
Query: 493 TKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD----KYNIPRGTLIIMSTQDAS 326
+ R + L+A I+E LRL P P+L +P +D ++ + +GT +I++
Sbjct: 345 SD-RNRLLLLEATIREVLRLRPVAPML---IPHKANVDSSIGEFAVDKGTEVIINLWALH 400
Query: 325 LKESNYDDANTFCPERWLKSDSNEY--HLFASIPFGYGARKCLGQNIAETMMSLLTVKLL 152
E + + F PER+L + + +PFG G R C+G+ +A + L+ LL
Sbjct: 401 HNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLL 460
Query: 151 QKYKLE 134
Q++ LE
Sbjct: 461 QRFDLE 466
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 78.6 bits (185), Expect = 3e-14
Identities = 51/170 (30%), Positives = 90/170 (52%), Gaps = 3/170 (1%)
Frame = -2
Query: 637 MDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLT-KIREQTPYL 464
+D+L+ G T ++ S+ + +L + + Q+ L +E+ P + K R + P L
Sbjct: 286 VDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLL 345
Query: 463 QACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFC 287
A I E LRL P +P+ L + ++ Y+IP GT+II + Q A L E+ ++ + F
Sbjct: 346 NATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFW 405
Query: 286 PERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKL 137
P+R+L+ N ++ FG GA CLG+ +A + ++ +LLQ + L
Sbjct: 406 PDRFLEPGKNS----RALAFGCGAPVCLGEPLARLDLFVVLTRLLQAFTL 451
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 78.2 bits (184), Expect = 3e-14
Identities = 53/197 (26%), Positives = 92/197 (46%), Gaps = 5/197 (2%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLTKIR 482
E++ + ++++ G T T+ + + ++A Y Q + KEI P K K +
Sbjct: 298 ENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCK 357
Query: 481 EQTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYD 305
PY +A + E LR +P+ + ++ + Y+IP+GT +I + E +
Sbjct: 358 --MPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWR 415
Query: 304 DANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYHY 125
D F PER+L S A +PF G R CLG+++A M L LLQ++ L + +
Sbjct: 416 DPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPH 475
Query: 124 ---GDLEPTRSFIARPK 83
DL+P +P+
Sbjct: 476 ELVPDLKPRLGMTLQPQ 492
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 78.2 bits (184), Expect = 3e-14
Identities = 53/197 (26%), Positives = 92/197 (46%), Gaps = 5/197 (2%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLTKIR 482
E++ + ++++ G T T+ + + ++A Y Q + KEI P K K +
Sbjct: 298 ENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCK 357
Query: 481 EQTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYD 305
PY +A + E LR +P+ + ++ + Y+IP+GT +I + E +
Sbjct: 358 --MPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWR 415
Query: 304 DANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYHY 125
D F PER+L S A +PF G R CLG+++A M L LLQ++ L + +
Sbjct: 416 DPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPH 475
Query: 124 ---GDLEPTRSFIARPK 83
DL+P +P+
Sbjct: 476 ELVPDLKPRLGMTLQPQ 492
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 78.2 bits (184), Expect = 3e-14
Identities = 53/197 (26%), Positives = 92/197 (46%), Gaps = 5/197 (2%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENF-PEQKIMDLTKIR 482
E++ + ++++ G T T+ + + ++A Y Q + KEI P K K +
Sbjct: 298 ENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCK 357
Query: 481 EQTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYD 305
PY +A + E LR +P+ + ++ + Y+IP+GT +I + E +
Sbjct: 358 --MPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWR 415
Query: 304 DANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEYHY 125
D F PER+L S A +PF G R CLG+++A M L LLQ++ L + +
Sbjct: 416 DPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPH 475
Query: 124 ---GDLEPTRSFIARPK 83
DL+P +P+
Sbjct: 476 ELVPDLKPRLGMTLQPQ 492
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 77.8 bits (183), Expect = 5e-14
Identities = 45/165 (27%), Positives = 74/165 (44%)
Frame = -2
Query: 628 LLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIREQTPYLQACIK 449
L+ G IT++ SF Y LA Q+ L +E+ + + + E PYL I
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIA 399
Query: 448 ETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLK 269
ETLR+ PP TR ++ + IP G ++ M+ ++ F PER+
Sbjct: 400 ETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPENFNPERFTA 459
Query: 268 SDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
++ F +PFG G R CLG + + L + +L K++ +
Sbjct: 460 EARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQ 504
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 77.4 bits (182), Expect = 6e-14
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 1/173 (0%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E++ +D+ G T +++ + L Y+A Y + Q+ + EI + + T RE
Sbjct: 299 ENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQ-QPSTAARE 357
Query: 478 QTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
PY A I E R+ IP+ + R + + TL Y++P+GT+I+ + + +
Sbjct: 358 SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWAT 417
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKY 143
+TF P+ +L++ + A +PF G R CLG+ +A T + + L+QK+
Sbjct: 418 PDTFNPDHFLENGQFKKRE-AFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 77.4 bits (182), Expect = 6e-14
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 1/173 (0%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E++ +D+ G T +++ + L Y+A Y + Q+ + EI + + T RE
Sbjct: 299 ENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQ-QPSTAARE 357
Query: 478 QTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
PY A I E R+ IP+ + R + + TL Y++P+GT+I+ + + +
Sbjct: 358 SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWAT 417
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKY 143
+TF P+ +L++ + A +PF G R CLG+ +A T + + L+QK+
Sbjct: 418 PDTFNPDHFLENGQFKKRE-AFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 77.4 bits (182), Expect = 6e-14
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 1/173 (0%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E++ +D+ G T +++ + L Y+A Y + Q+ + EI + + T RE
Sbjct: 299 ENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQ-QPSTAARE 357
Query: 478 QTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
PY A I E R+ IP+ + R + + TL Y++P+GT+I+ + + +
Sbjct: 358 SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWAT 417
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKY 143
+TF P+ +L++ + A +PF G R CLG+ +A T + + L+QK+
Sbjct: 418 PDTFNPDHFLENGQFKKRE-AFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 77.4 bits (182), Expect = 6e-14
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 1/173 (0%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E++ +D+ G T +++ + L Y+A Y + Q+ + EI + + T RE
Sbjct: 299 ENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQ-QPSTAARE 357
Query: 478 QTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
PY A I E R+ IP+ + R + + TL Y++P+GT+I+ + + +
Sbjct: 358 SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWAT 417
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKY 143
+TF P+ +L++ + A +PF G R CLG+ +A T + + L+QK+
Sbjct: 418 PDTFNPDHFLENGQFKKRE-AFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 77.0 bits (181), Expect = 8e-14
Identities = 48/186 (25%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLT 491
+++ E I +++D+ G +T+T++TS+ L YL + Q+ + +E+ + L+
Sbjct: 301 QLSDEKIINIVLDLFGAGFDTVTTATSWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS 360
Query: 490 KIREQTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKES 314
R PY++A I ET R + +P + ++ +L + IP+G + ++ +
Sbjct: 361 D-RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQIDHDQK 419
Query: 313 NYDDANTFCPERWLKSDSNEYHLFAS--IPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + + F PER+L D + + I FG G RKC+G+ IA + L LLQ+ +
Sbjct: 420 LWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVE 479
Query: 139 LEYHYG 122
G
Sbjct: 480 FSVPLG 485
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 77.0 bits (181), Expect = 8e-14
Identities = 47/173 (27%), Positives = 87/173 (50%), Gaps = 1/173 (0%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E++ +D+ G T +++ + L Y+A Y + Q+ + EI + + T RE
Sbjct: 299 ENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQVEIDRVIGQGQ-QPSTAARE 357
Query: 478 QTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
PY A I E R+ IP+ + R + + TL Y++P+GT+I+ + + +
Sbjct: 358 SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWAT 417
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKY 143
+TF P+ +L++ + A +PF G R CLG+ +A T + + L+QK+
Sbjct: 418 PDTFNPDHFLENGQFKKRE-AFMPFSIGKRACLGEQLARTELFIFFTSLMQKF 469
>Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for
aromatase P-450. ).
Length = 503
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/215 (26%), Positives = 110/215 (51%), Gaps = 6/215 (2%)
Frame = -2
Query: 760 EQAISYKAKEI--EEQYPNSNILINAMLLGQEK--MNPEDIATVIMDMLLIGVNTITSST 593
E I+ K + I EE+ ++L +++ + E++ I++ML+ +T++ S
Sbjct: 256 EVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSL 315
Query: 592 SFLLYYLAKYQKAQKILYKEIQENFPEQ--KIMDLTKIREQTPYLQACIKETLRLTPPIP 419
F+L+ +AK+ ++ + KEIQ E+ KI D+ K++ ++ I E++R P +
Sbjct: 316 FFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLK----VMENFIYESMRYQPVVD 371
Query: 418 VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFA 239
++ R ++ +D Y + +GT II++ E + N F E + K+ Y
Sbjct: 372 LVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEF-FPKPNEFTLENFAKNVPYRYFQ-- 428
Query: 238 SIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
PFG+G R C G+ IA MM + V LL+++ ++
Sbjct: 429 --PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVK 461
>X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for
aromatase (estrogen synthetase). ).
Length = 503
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/215 (26%), Positives = 110/215 (51%), Gaps = 6/215 (2%)
Frame = -2
Query: 760 EQAISYKAKEI--EEQYPNSNILINAMLLGQEK--MNPEDIATVIMDMLLIGVNTITSST 593
E I+ K + I EE+ ++L +++ + E++ I++ML+ +T++ S
Sbjct: 256 EVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSL 315
Query: 592 SFLLYYLAKYQKAQKILYKEIQENFPEQ--KIMDLTKIREQTPYLQACIKETLRLTPPIP 419
F+L+ +AK+ ++ + KEIQ E+ KI D+ K++ ++ I E++R P +
Sbjct: 316 FFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLK----VMENFIYESMRYQPVVD 371
Query: 418 VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFA 239
++ R ++ +D Y + +GT II++ E + N F E + K+ Y
Sbjct: 372 LVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEF-FPKPNEFTLENFAKNVPYRYFQ-- 428
Query: 238 SIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
PFG+G R C G+ IA MM + V LL+++ ++
Sbjct: 429 --PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVK 461
>M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase
cytochrome P-450 gene, exon 10. ).
Length = 503
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/215 (26%), Positives = 110/215 (51%), Gaps = 6/215 (2%)
Frame = -2
Query: 760 EQAISYKAKEI--EEQYPNSNILINAMLLGQEK--MNPEDIATVIMDMLLIGVNTITSST 593
E I+ K + I EE+ ++L +++ + E++ I++ML+ +T++ S
Sbjct: 256 EVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSL 315
Query: 592 SFLLYYLAKYQKAQKILYKEIQENFPEQ--KIMDLTKIREQTPYLQACIKETLRLTPPIP 419
F+L+ +AK+ ++ + KEIQ E+ KI D+ K++ ++ I E++R P +
Sbjct: 316 FFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLK----VMENFIYESMRYQPVVD 371
Query: 418 VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFA 239
++ R ++ +D Y + +GT II++ E + N F E + K+ Y
Sbjct: 372 LVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEF-FPKPNEFTLENFAKNVPYRYFQ-- 428
Query: 238 SIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
PFG+G R C G+ IA MM + V LL+++ ++
Sbjct: 429 --PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVK 461
>M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase
mRNA, complete cds. ).
Length = 503
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/215 (26%), Positives = 110/215 (51%), Gaps = 6/215 (2%)
Frame = -2
Query: 760 EQAISYKAKEI--EEQYPNSNILINAMLLGQEK--MNPEDIATVIMDMLLIGVNTITSST 593
E I+ K + I EE+ ++L +++ + E++ I++ML+ +T++ S
Sbjct: 256 EVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSL 315
Query: 592 SFLLYYLAKYQKAQKILYKEIQENFPEQ--KIMDLTKIREQTPYLQACIKETLRLTPPIP 419
F+L+ +AK+ ++ + KEIQ E+ KI D+ K++ ++ I E++R P +
Sbjct: 316 FFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLK----VMENFIYESMRYQPVVD 371
Query: 418 VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFA 239
++ R ++ +D Y + +GT II++ E + N F E + K+ Y
Sbjct: 372 LVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEF-FPKPNEFTLENFAKNVPYRYFQ-- 428
Query: 238 SIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
PFG+G R C G+ IA MM + V LL+++ ++
Sbjct: 429 --PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVK 461
>M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase
(Aro1) mRNA, complete cds. ).
Length = 419
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/215 (26%), Positives = 110/215 (51%), Gaps = 6/215 (2%)
Frame = -2
Query: 760 EQAISYKAKEI--EEQYPNSNILINAMLLGQEK--MNPEDIATVIMDMLLIGVNTITSST 593
E I+ K + I EE+ ++L +++ + E++ I++ML+ +T++ S
Sbjct: 172 EVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSL 231
Query: 592 SFLLYYLAKYQKAQKILYKEIQENFPEQ--KIMDLTKIREQTPYLQACIKETLRLTPPIP 419
F+L+ +AK+ ++ + KEIQ E+ KI D+ K++ ++ I E++R P +
Sbjct: 232 FFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLK----VMENFIYESMRYQPVVD 287
Query: 418 VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFA 239
++ R ++ +D Y + +GT II++ E + N F E + K+ Y
Sbjct: 288 LVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEF-FPKPNEFTLENFAKNVPYRYFQ-- 344
Query: 238 SIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
PFG+G R C G+ IA MM + V LL+++ ++
Sbjct: 345 --PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVK 377
>DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfamily
19 subfamily A polypeptide 1 protein.
Length = 503
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/215 (26%), Positives = 110/215 (51%), Gaps = 6/215 (2%)
Frame = -2
Query: 760 EQAISYKAKEI--EEQYPNSNILINAMLLGQEK--MNPEDIATVIMDMLLIGVNTITSST 593
E I+ K + I EE+ ++L +++ + E++ I++ML+ +T++ S
Sbjct: 256 EVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSL 315
Query: 592 SFLLYYLAKYQKAQKILYKEIQENFPEQ--KIMDLTKIREQTPYLQACIKETLRLTPPIP 419
F+L+ +AK+ ++ + KEIQ E+ KI D+ K++ ++ I E++R P +
Sbjct: 316 FFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLK----VMENFIYESMRYQPVVD 371
Query: 418 VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFA 239
++ R ++ +D Y + +GT II++ E + N F E + K+ Y
Sbjct: 372 LVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEF-FPKPNEFTLENFAKNVPYRYFQ-- 428
Query: 238 SIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
PFG+G R C G+ IA MM + V LL+++ ++
Sbjct: 429 --PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVK 461
>BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/215 (26%), Positives = 110/215 (51%), Gaps = 6/215 (2%)
Frame = -2
Query: 760 EQAISYKAKEI--EEQYPNSNILINAMLLGQEK--MNPEDIATVIMDMLLIGVNTITSST 593
E I+ K + I EE+ ++L +++ + E++ I++ML+ +T++ S
Sbjct: 256 EVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSL 315
Query: 592 SFLLYYLAKYQKAQKILYKEIQENFPEQ--KIMDLTKIREQTPYLQACIKETLRLTPPIP 419
F+L+ +AK+ ++ + KEIQ E+ KI D+ K++ ++ I E++R P +
Sbjct: 316 FFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLK----VMENFIYESMRYQPVVD 371
Query: 418 VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFA 239
++ R ++ +D Y + +GT II++ E + N F E + K+ Y
Sbjct: 372 LVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEF-FPKPNEFTLENFAKNVPYRYFQ-- 428
Query: 238 SIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
PFG+G R C G+ IA MM + V LL+++ ++
Sbjct: 429 --PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVK 461
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 76.2 bits (179), Expect = 1e-13
Identities = 53/190 (27%), Positives = 96/190 (50%), Gaps = 7/190 (3%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E I ++ D+ G +T+T++ S+ L YL + Q+ + KE+ ++ L+ R
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD-RP 363
Query: 478 QTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q PYL+A I ET R +P +P + ++ TL+ + IP+ + ++ + ++D
Sbjct: 364 QLPYLEAFILETFRHSPFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 301 ANTFCPERWLKSDSNEYHLFAS---IPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEY 131
+ F PER+L +D + S + FG G R+C+G+ +A+ + L LLQ+ +
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483
Query: 130 HYG---DLEP 110
G DL P
Sbjct: 484 PPGVKVDLTP 493
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 76.2 bits (179), Expect = 1e-13
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK----I 503
+++ EDI + + G +T ++ ++ LY L + QK + E+ + F + +
Sbjct: 313 RLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATV 372
Query: 502 MDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASL 323
DL K+R YL+ IKETLRL P +P+ R + ++ + Y + +GT ++
Sbjct: 373 EDLKKLR----YLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHR 428
Query: 322 KESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKY 143
+ + F PER+ ++ H +A +PF G R C+GQ A + +L+ +
Sbjct: 429 DPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHF 488
Query: 142 KLE 134
+E
Sbjct: 489 WIE 491
>BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/215 (26%), Positives = 110/215 (51%), Gaps = 6/215 (2%)
Frame = -2
Query: 760 EQAISYKAKEI--EEQYPNSNILINAMLLGQEK--MNPEDIATVIMDMLLIGVNTITSST 593
E I+ K + I EE+ ++L +++ + E++ I++ML+ +T++ S
Sbjct: 256 EVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSL 315
Query: 592 SFLLYYLAKYQKAQKILYKEIQENFPEQ--KIMDLTKIREQTPYLQACIKETLRLTPPIP 419
F+L+ +AK+ ++ + KEIQ E+ KI D+ K++ ++ I E++R P +
Sbjct: 316 FFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLK----VMENFIYESMRYQPVVD 371
Query: 418 VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFA 239
++ R ++ +D Y + +GT II++ E + N F E + K+ Y
Sbjct: 372 LVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEF-FPKPNEFTLENFAKNVPYRYFQ-- 428
Query: 238 SIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
PFG+G R C G+ IA MM + V LL+++ ++
Sbjct: 429 --PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVK 461
>AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 76.2 bits (179), Expect = 1e-13
Identities = 57/215 (26%), Positives = 110/215 (51%), Gaps = 6/215 (2%)
Frame = -2
Query: 760 EQAISYKAKEI--EEQYPNSNILINAMLLGQEK--MNPEDIATVIMDMLLIGVNTITSST 593
E I+ K + I EE+ ++L +++ + E++ I++ML+ +T++ S
Sbjct: 256 EVLIAEKRRRISTEEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSL 315
Query: 592 SFLLYYLAKYQKAQKILYKEIQENFPEQ--KIMDLTKIREQTPYLQACIKETLRLTPPIP 419
F+L+ +AK+ ++ + KEIQ E+ KI D+ K++ ++ I E++R P +
Sbjct: 316 FFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLK----VMENFIYESMRYQPVVD 371
Query: 418 VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFA 239
++ R ++ +D Y + +GT II++ E + N F E + K+ Y
Sbjct: 372 LVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLEF-FPKPNEFTLENFAKNVPYRYFQ-- 428
Query: 238 SIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
PFG+G R C G+ IA MM + V LL+++ ++
Sbjct: 429 --PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVK 461
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 76.2 bits (179), Expect = 1e-13
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK----I 503
+++ EDI + + G +T ++ ++ LY L + QK + E+ + F + +
Sbjct: 313 RLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATV 372
Query: 502 MDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASL 323
DL K+R YL+ IKETLRL P +P+ R + ++ + Y + +GT ++
Sbjct: 373 EDLKKLR----YLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHR 428
Query: 322 KESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKY 143
+ + F PER+ ++ H +A +PF G R C+GQ A + +L+ +
Sbjct: 429 DPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHF 488
Query: 142 KLE 134
+E
Sbjct: 489 WIE 491
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 76.2 bits (179), Expect = 1e-13
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK----I 503
+++ EDI + + G +T ++ ++ LY L + QK + E+ + F + +
Sbjct: 291 RLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATV 350
Query: 502 MDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASL 323
DL K+R YL+ IKETLRL P +P+ R + ++ + Y + +GT ++
Sbjct: 351 EDLKKLR----YLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHR 406
Query: 322 KESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKY 143
+ + F PER+ ++ H +A +PF G R C+GQ A + +L+ +
Sbjct: 407 DPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHF 466
Query: 142 KLE 134
+E
Sbjct: 467 WIE 469
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 76.2 bits (179), Expect = 1e-13
Identities = 47/183 (25%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQK----I 503
+++ EDI + + G +T ++ ++ LY L + QK + E+ + F + +
Sbjct: 313 RLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATV 372
Query: 502 MDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLDKYNIPRGTLIIMSTQDASL 323
DL K+R YL+ IKETLRL P +P+ R + ++ + Y + +GT ++
Sbjct: 373 EDLKKLR----YLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHR 428
Query: 322 KESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKY 143
+ + F PER+ ++ H +A +PF G R C+GQ A + +L+ +
Sbjct: 429 DPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHF 488
Query: 142 KLE 134
+E
Sbjct: 489 WIE 491
>M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatase
protein.
Length = 419
Score = 75.4 bits (177), Expect = 2e-13
Identities = 53/202 (26%), Positives = 104/202 (51%), Gaps = 4/202 (1%)
Frame = -2
Query: 727 EEQYPNSNILINAMLLGQEK--MNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKA 554
EE+ ++L +++ + E++ I++ML+ +T++ S F+L+ +AK+
Sbjct: 185 EEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNV 244
Query: 553 QKILYKEIQENFPEQ--KIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD 380
++ + KEIQ E+ KI D+ K++ ++ I E++R P + ++ R ++ +D
Sbjct: 245 EEAIIKEIQTVIGERDIKIDDIQKLK----VMENFIYESMRYQPVVDLVMRKALEDDVID 300
Query: 379 KYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLG 200
Y + +GT II++ E + N F E + K+ Y PFG+G R C G
Sbjct: 301 GYPVKKGTNIILNIGRMHRLEF-FPKPNEFTLENFAKNVPYRYFQ----PFGFGPRGCAG 355
Query: 199 QNIAETMMSLLTVKLLQKYKLE 134
+ IA MM + V LL+++ ++
Sbjct: 356 KYIAMVMMKAILVTLLRRFHVK 377
>J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein.
Length = 503
Score = 75.4 bits (177), Expect = 2e-13
Identities = 53/202 (26%), Positives = 104/202 (51%), Gaps = 4/202 (1%)
Frame = -2
Query: 727 EEQYPNSNILINAMLLGQEK--MNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKA 554
EE+ ++L +++ + E++ I++ML+ +T++ S F+L+ +AK+
Sbjct: 269 EEKLEECMDFATELILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNV 328
Query: 553 QKILYKEIQENFPEQ--KIMDLTKIREQTPYLQACIKETLRLTPPIPVLTRILPKNITLD 380
++ + KEIQ E+ KI D+ K++ ++ I E++R P + ++ R ++ +D
Sbjct: 329 EEAIIKEIQTVIGERDIKIDDIQKLK----VMENFIYESMRYQPVVDLVMRKALEDDVID 384
Query: 379 KYNIPRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLG 200
Y + +GT II++ E + N F E + K+ Y PFG+G R C G
Sbjct: 385 GYPVKKGTNIILNIGRMHRLEF-FPKPNEFTLENFAKNVPYRYFQ----PFGFGPRGCAG 439
Query: 199 QNIAETMMSLLTVKLLQKYKLE 134
+ IA MM + V LL+++ ++
Sbjct: 440 KYIAMVMMKAILVTLLRRFHVK 461
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 74.9 bits (176), Expect = 3e-13
Identities = 47/186 (25%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLT 491
+++ E I +++D+ G +T+T++ S+ L YL + Q+ + +E+ + L+
Sbjct: 301 QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS 360
Query: 490 KIREQTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKES 314
R PY++A I ET R + +P + ++ +L + IP+G + ++ + +
Sbjct: 361 D-RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQK 419
Query: 313 NYDDANTFCPERWLKSDSNEYHLFAS--IPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + + F PER+L D + + I FG G RKC+G+ IA + L LLQ+ +
Sbjct: 420 LWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVE 479
Query: 139 LEYHYG 122
G
Sbjct: 480 FSVPLG 485
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 74.9 bits (176), Expect = 3e-13
Identities = 46/186 (24%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLT 491
+++ E I +++D+ G +T+T++ S+ L YL + Q+ + +E+ + L+
Sbjct: 301 QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS 360
Query: 490 KIREQTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKES 314
R PY++A I ET R + +P + ++ +L + IP+G + ++ + +
Sbjct: 361 D-RSHLPYMEAFILETFRHSSLVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQK 419
Query: 313 NYDDANTFCPERWLKSDSNEYHLFAS--IPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + + F PER+L D + + I FG G RKC+G+ +A + L LLQ+ +
Sbjct: 420 LWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETVARWEVFLFLAILLQRVE 479
Query: 139 LEYHYG 122
G
Sbjct: 480 FSVPLG 485
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 74.9 bits (176), Expect = 3e-13
Identities = 47/186 (25%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLT 491
+++ E I +++D+ G +T+T++ S+ L YL + Q+ + +E+ + L+
Sbjct: 301 QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS 360
Query: 490 KIREQTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKES 314
R PY++A I ET R + +P + ++ +L + IP+G + ++ + +
Sbjct: 361 D-RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQK 419
Query: 313 NYDDANTFCPERWLKSDSNEYHLFAS--IPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + + F PER+L D + + I FG G RKC+G+ IA + L LLQ+ +
Sbjct: 420 LWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVE 479
Query: 139 LEYHYG 122
G
Sbjct: 480 FSVPLG 485
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 74.9 bits (176), Expect = 3e-13
Identities = 44/176 (25%), Positives = 80/176 (45%), Gaps = 1/176 (0%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
+ I + D+ G T +++ + L L KY + ++ L++EI +I + K R+
Sbjct: 287 DGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAI-KDRQ 345
Query: 478 QTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
+ PY+ A + E R +P L ++ Y IP+GT+++ + + D
Sbjct: 346 EMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPD 405
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PE +L + + PF G R C G+ +A T + LL +LQ + L+
Sbjct: 406 PEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARTELFLLLCAILQHFNLK 461
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 74.9 bits (176), Expect = 3e-13
Identities = 52/198 (26%), Positives = 91/198 (45%), Gaps = 9/198 (4%)
Frame = -2
Query: 700 LINAMLL--GQEKMNP------EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKI 545
L++A LL QE+ NP +++ ++ +L G T++++ + L L KY QK
Sbjct: 268 LVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKW 327
Query: 544 LYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNI 368
+ +E+ + L R + PY A + E RL +P+ + R L + Y +
Sbjct: 328 VREELNRELGAGQAPSLGD-RTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTL 386
Query: 367 PRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIA 188
P+GT + + + F P+R+L +D A +PF G R CLG+ +A
Sbjct: 387 PQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLA 446
Query: 187 ETMMSLLTVKLLQKYKLE 134
+ + L +LQ + LE
Sbjct: 447 KAELFLFFTTILQAFSLE 464
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 74.9 bits (176), Expect = 3e-13
Identities = 47/186 (25%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLT 491
+++ E I +++D+ G +T+T++ S+ L YL + Q+ + +E+ + L+
Sbjct: 301 QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS 360
Query: 490 KIREQTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKES 314
R PY++A I ET R + +P + ++ +L + IP+G + ++ + +
Sbjct: 361 D-RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQK 419
Query: 313 NYDDANTFCPERWLKSDSNEYHLFAS--IPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + + F PER+L D + + I FG G RKC+G+ IA + L LLQ+ +
Sbjct: 420 LWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVE 479
Query: 139 LEYHYG 122
G
Sbjct: 480 FSVPLG 485
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 74.9 bits (176), Expect = 3e-13
Identities = 52/198 (26%), Positives = 91/198 (45%), Gaps = 9/198 (4%)
Frame = -2
Query: 700 LINAMLL--GQEKMNP------EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKI 545
L++A LL QE+ NP +++ ++ +L G T++++ + L L KY QK
Sbjct: 268 LVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKW 327
Query: 544 LYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNI 368
+ +E+ + L R + PY A + E RL +P+ + R L + Y +
Sbjct: 328 VREELNRELGAGQAPSLGD-RTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTL 386
Query: 367 PRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIA 188
P+GT + + + F P+R+L +D A +PF G R CLG+ +A
Sbjct: 387 PQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLA 446
Query: 187 ETMMSLLTVKLLQKYKLE 134
+ + L +LQ + LE
Sbjct: 447 KAELFLFFTTILQAFSLE 464
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 74.9 bits (176), Expect = 3e-13
Identities = 47/186 (25%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLT 491
+++ E I +++D+ G +T+T++ S+ L YL + Q+ + +E+ + L+
Sbjct: 273 QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS 332
Query: 490 KIREQTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKES 314
R PY++A I ET R + +P + ++ +L + IP+G + ++ + +
Sbjct: 333 D-RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQK 391
Query: 313 NYDDANTFCPERWLKSDSNEYHLFAS--IPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + + F PER+L D + + I FG G RKC+G+ IA + L LLQ+ +
Sbjct: 392 LWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVE 451
Query: 139 LEYHYG 122
G
Sbjct: 452 FSVPLG 457
>AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1
protein.
Length = 251
Score = 74.9 bits (176), Expect = 3e-13
Identities = 47/186 (25%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLT 491
+++ E I +++D+ G +T+T++ S+ L YL + Q+ + +E+ + L+
Sbjct: 40 QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS 99
Query: 490 KIREQTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKES 314
R PY++A I ET R + +P + ++ +L + IP+G + ++ + +
Sbjct: 100 D-RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQK 158
Query: 313 NYDDANTFCPERWLKSDSNEYHLFAS--IPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + + F PER+L D + + I FG G RKC+G+ IA + L LLQ+ +
Sbjct: 159 LWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVE 218
Query: 139 LEYHYG 122
G
Sbjct: 219 FSVPLG 224
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 74.9 bits (176), Expect = 3e-13
Identities = 47/186 (25%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLT 491
+++ E I +++D+ G +T+T++ S+ L YL + Q+ + +E+ + L+
Sbjct: 301 QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS 360
Query: 490 KIREQTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKES 314
R PY++A I ET R + +P + ++ +L + IP+G + ++ + +
Sbjct: 361 D-RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQK 419
Query: 313 NYDDANTFCPERWLKSDSNEYHLFAS--IPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + + F PER+L D + + I FG G RKC+G+ IA + L LLQ+ +
Sbjct: 420 LWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVE 479
Query: 139 LEYHYG 122
G
Sbjct: 480 FSVPLG 485
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 74.9 bits (176), Expect = 3e-13
Identities = 52/198 (26%), Positives = 91/198 (45%), Gaps = 9/198 (4%)
Frame = -2
Query: 700 LINAMLL--GQEKMNP------EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKI 545
L++A LL QE+ NP +++ ++ +L G T++++ + L L KY QK
Sbjct: 268 LVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKW 327
Query: 544 LYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNI 368
+ +E+ + L R + PY A + E RL +P+ + R L + Y +
Sbjct: 328 VREELNRELGAGQAPSLGD-RTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTL 386
Query: 367 PRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIA 188
P+GT + + + F P+R+L +D A +PF G R CLG+ +A
Sbjct: 387 PQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLA 446
Query: 187 ETMMSLLTVKLLQKYKLE 134
+ + L +LQ + LE
Sbjct: 447 KAELFLFFTTILQAFSLE 464
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 74.9 bits (176), Expect = 3e-13
Identities = 52/198 (26%), Positives = 91/198 (45%), Gaps = 9/198 (4%)
Frame = -2
Query: 700 LINAMLL--GQEKMNP------EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKI 545
L++A LL QE+ NP +++ ++ +L G T++++ + L L KY QK
Sbjct: 268 LVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKW 327
Query: 544 LYKEIQENFPEQKIMDLTKIREQTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNI 368
+ +E+ + L R + PY A + E RL +P+ + R L + Y +
Sbjct: 328 VREELNRELGAGQAPSLGD-RTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTL 386
Query: 367 PRGTLIIMSTQDASLKESNYDDANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIA 188
P+GT + + + F P+R+L +D A +PF G R CLG+ +A
Sbjct: 387 PQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLA 446
Query: 187 ETMMSLLTVKLLQKYKLE 134
+ + L +LQ + LE
Sbjct: 447 KAELFLFFTTILQAFSLE 464
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 74.9 bits (176), Expect = 3e-13
Identities = 47/186 (25%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLT 491
+++ E I +++D+ G +T+T++ S+ L YL + Q+ + +E+ + L+
Sbjct: 301 QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS 360
Query: 490 KIREQTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKES 314
R PY++A I ET R + +P + ++ +L + IP+G + ++ + +
Sbjct: 361 D-RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQK 419
Query: 313 NYDDANTFCPERWLKSDSNEYHLFAS--IPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + + F PER+L D + + I FG G RKC+G+ IA + L LLQ+ +
Sbjct: 420 LWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAILLQRVE 479
Query: 139 LEYHYG 122
G
Sbjct: 480 FSVPLG 485
>M12079-1|AAA52152.1| 191|Homo sapiens POR protein.
Length = 191
Score = 74.5 bits (175), Expect = 4e-13
Identities = 46/186 (24%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLT 491
+++ E I +++D+ G +T+T++ S+ L YL + Q+ + +E+ + L+
Sbjct: 7 QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS 66
Query: 490 KIREQTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKES 314
R PY++A I ET R + +P + ++ +L + IP+G + ++ + +
Sbjct: 67 D-RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQK 125
Query: 313 NYDDANTFCPERWLKSDSNEYHLFAS--IPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + + F PER+L D + + I FG G RKC+G+ +A + L LLQ+ +
Sbjct: 126 LWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETVARWEVFLFLAILLQRVE 185
Query: 139 LEYHYG 122
G
Sbjct: 186 FSVPLG 191
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 74.5 bits (175), Expect = 4e-13
Identities = 46/186 (24%), Positives = 92/186 (49%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 KMNPEDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLT 491
+++ E I +++D+ G +T+T++ S+ L YL + Q+ + +E+ + L+
Sbjct: 301 QLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLS 360
Query: 490 KIREQTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKES 314
R PY++A I ET R + +P + ++ +L + IP+G + ++ + +
Sbjct: 361 D-RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQK 419
Query: 313 NYDDANTFCPERWLKSDSNEYHLFAS--IPFGYGARKCLGQNIAETMMSLLTVKLLQKYK 140
+ + + F PER+L D + + I FG G RKC+G+ +A + L LLQ+ +
Sbjct: 420 LWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETVARWEVFLFLAILLQRVE 479
Query: 139 LEYHYG 122
G
Sbjct: 480 FSVPLG 485
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 73.7 bits (173), Expect = 7e-13
Identities = 43/176 (24%), Positives = 80/176 (45%), Gaps = 1/176 (0%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
+ I + D+ G T +++ + L L KY + ++ L++EI +I + K R+
Sbjct: 287 DGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAI-KDRQ 345
Query: 478 QTPYLQACIKETLRLTPPIPV-LTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
+ PY+ A ++E R +P L ++ Y IP+GT+++ + + D
Sbjct: 346 EMPYMDAVVREIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPD 405
Query: 301 ANTFCPERWLKSDSNEYHLFASIPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLE 134
F PE +L + + PF G R C G+ +A + LL +LQ + L+
Sbjct: 406 PEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLK 461
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 72.9 bits (171), Expect = 1e-12
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 7/190 (3%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E I ++ D+ G +T+T++ S+ L YL + Q+ + KE+ ++ L+ R
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD-RP 363
Query: 478 QTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q PYL+A I ET R + +P + ++ TL+ + IP+ + ++ + ++D
Sbjct: 364 QLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 301 ANTFCPERWLKSDSNEYHLFAS---IPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEY 131
+ F PER+L +D + S + FG G R+C+G+ +A+ + L LLQ+ +
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483
Query: 130 HYG---DLEP 110
G DL P
Sbjct: 484 PPGVKVDLTP 493
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 72.9 bits (171), Expect = 1e-12
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 7/190 (3%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E I ++ D+ G +T+T++ S+ L YL + Q+ + KE+ ++ L+ R
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD-RP 363
Query: 478 QTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q PYL+A I ET R + +P + ++ TL+ + IP+ + ++ + ++D
Sbjct: 364 QLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 301 ANTFCPERWLKSDSNEYHLFAS---IPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEY 131
+ F PER+L +D + S + FG G R+C+G+ +A+ + L LLQ+ +
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483
Query: 130 HYG---DLEP 110
G DL P
Sbjct: 484 PPGVKVDLTP 493
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 72.9 bits (171), Expect = 1e-12
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 7/190 (3%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E I ++ D+ G +T+T++ S+ L YL + Q+ + KE+ ++ L+ R
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD-RP 363
Query: 478 QTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q PYL+A I ET R + +P + ++ TL+ + IP+ + ++ + ++D
Sbjct: 364 QLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 301 ANTFCPERWLKSDSNEYHLFAS---IPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEY 131
+ F PER+L +D + S + FG G R+C+G+ +A+ + L LLQ+ +
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483
Query: 130 HYG---DLEP 110
G DL P
Sbjct: 484 PPGVKVDLTP 493
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 72.9 bits (171), Expect = 1e-12
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 7/190 (3%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E I ++ D+ G +T+T++ S+ L YL + Q+ + KE+ ++ L+ R
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD-RP 363
Query: 478 QTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q PYL+A I ET R + +P + ++ TL+ + IP+ + ++ + ++D
Sbjct: 364 QLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 301 ANTFCPERWLKSDSNEYHLFAS---IPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEY 131
+ F PER+L +D + S + FG G R+C+G+ +A+ + L LLQ+ +
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483
Query: 130 HYG---DLEP 110
G DL P
Sbjct: 484 PPGVKVDLTP 493
>DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 72.9 bits (171), Expect = 1e-12
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 7/190 (3%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E I ++ D+ G +T+T++ S+ L YL + Q+ + KE+ ++ L+ R
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD-RP 363
Query: 478 QTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q PYL+A I ET R + +P + ++ TL+ + IP+ + ++ + ++D
Sbjct: 364 QLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 301 ANTFCPERWLKSDSNEYHLFAS---IPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEY 131
+ F PER+L +D + S + FG G R+C+G+ +A+ + L LLQ+ +
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483
Query: 130 HYG---DLEP 110
G DL P
Sbjct: 484 PPGVKVDLTP 493
>BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 72.9 bits (171), Expect = 1e-12
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 7/190 (3%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E I ++ D+ G +T+T++ S+ L YL + Q+ + KE+ ++ L+ R
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD-RP 363
Query: 478 QTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q PYL+A I ET R + +P + ++ TL+ + IP+ + ++ + ++D
Sbjct: 364 QLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 301 ANTFCPERWLKSDSNEYHLFAS---IPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEY 131
+ F PER+L +D + S + FG G R+C+G+ +A+ + L LLQ+ +
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483
Query: 130 HYG---DLEP 110
G DL P
Sbjct: 484 PPGVKVDLTP 493
>BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 72.9 bits (171), Expect = 1e-12
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 7/190 (3%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E I ++ D+ G +T+T++ S+ L YL + Q+ + KE+ ++ L+ R
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD-RP 363
Query: 478 QTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q PYL+A I ET R + +P + ++ TL+ + IP+ + ++ + ++D
Sbjct: 364 QLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 301 ANTFCPERWLKSDSNEYHLFAS---IPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEY 131
+ F PER+L +D + S + FG G R+C+G+ +A+ + L LLQ+ +
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483
Query: 130 HYG---DLEP 110
G DL P
Sbjct: 484 PPGVKVDLTP 493
>BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 72.9 bits (171), Expect = 1e-12
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 7/190 (3%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E I ++ D+ G +T+T++ S+ L YL + Q+ + KE+ ++ L+ R
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD-RP 363
Query: 478 QTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q PYL+A I ET R + +P + ++ TL+ + IP+ + ++ + ++D
Sbjct: 364 QLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 301 ANTFCPERWLKSDSNEYHLFAS---IPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEY 131
+ F PER+L +D + S + FG G R+C+G+ +A+ + L LLQ+ +
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483
Query: 130 HYG---DLEP 110
G DL P
Sbjct: 484 PPGVKVDLTP 493
>BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 72.9 bits (171), Expect = 1e-12
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 7/190 (3%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E I ++ D+ G +T+T++ S+ L YL + Q+ + KE+ ++ L+ R
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD-RP 363
Query: 478 QTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q PYL+A I ET R + +P + ++ TL+ + IP+ + ++ + ++D
Sbjct: 364 QLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 301 ANTFCPERWLKSDSNEYHLFAS---IPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEY 131
+ F PER+L +D + S + FG G R+C+G+ +A+ + L LLQ+ +
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483
Query: 130 HYG---DLEP 110
G DL P
Sbjct: 484 PPGVKVDLTP 493
>BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 72.9 bits (171), Expect = 1e-12
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 7/190 (3%)
Frame = -2
Query: 658 EDIATVIMDMLLIGVNTITSSTSFLLYYLAKYQKAQKILYKEIQENFPEQKIMDLTKIRE 479
E I ++ D+ G +T+T++ S+ L YL + Q+ + KE+ ++ L+ R
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSD-RP 363
Query: 478 QTPYLQACIKETLRLTPPIP-VLTRILPKNITLDKYNIPRGTLIIMSTQDASLKESNYDD 302
Q PYL+A I ET R + +P + ++ TL+ + IP+ + ++ + ++D
Sbjct: 364 QLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWED 423
Query: 301 ANTFCPERWLKSDSNEYHLFAS---IPFGYGARKCLGQNIAETMMSLLTVKLLQKYKLEY 131
+ F PER+L +D + S + FG G R+C+G+ +A+ + L LLQ+ +
Sbjct: 424 PSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483
Query: 130 HYG---DLEP 110
G DL P
Sbjct: 484 PPGVKVDLTP 493
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 120,647,694
Number of Sequences: 237096
Number of extensions: 2498865
Number of successful extensions: 4754
Number of sequences better than 10.0: 437
Number of HSP's better than 10.0 without gapping: 4187
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4420
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10538170902
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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