Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmte15c05
(868 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 254 2e-67
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 254 2e-67
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 254 2e-67
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 247 4e-65
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 247 4e-65
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 247 4e-65
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 247 4e-65
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 241 2e-63
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 234 4e-61
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 234 4e-61
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 234 4e-61
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 234 4e-61
AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens ... 231 2e-60
BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein. 199 9e-51
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 197 4e-50
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 197 4e-50
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 196 1e-49
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 189 1e-47
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 189 1e-47
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 189 1e-47
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 189 1e-47
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 189 1e-47
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 188 2e-47
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 188 2e-47
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 188 2e-47
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 188 2e-47
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 188 2e-47
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 188 2e-47
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 188 2e-47
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 188 2e-47
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 187 5e-47
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 187 5e-47
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 186 1e-46
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 186 1e-46
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 186 1e-46
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 186 1e-46
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 186 1e-46
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 186 1e-46
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 184 5e-46
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 184 5e-46
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 184 5e-46
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 184 5e-46
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 183 9e-46
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 183 9e-46
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 183 9e-46
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 183 9e-46
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 177 6e-44
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 176 1e-43
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 176 1e-43
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 175 1e-43
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 175 1e-43
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 134 5e-43
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 167 6e-41
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 163 1e-39
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 163 1e-39
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 163 1e-39
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 163 1e-39
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 163 1e-39
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 161 4e-39
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 161 4e-39
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 161 4e-39
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 161 4e-39
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 159 1e-38
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 158 2e-38
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 158 3e-38
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 158 3e-38
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 158 3e-38
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 158 3e-38
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 158 3e-38
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 157 4e-38
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 157 6e-38
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 157 6e-38
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 156 9e-38
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 156 9e-38
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 156 9e-38
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 156 9e-38
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 156 9e-38
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 156 9e-38
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 156 9e-38
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 156 9e-38
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 156 1e-37
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 156 1e-37
AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leuc... 156 1e-37
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 153 6e-37
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 146 7e-35
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 145 2e-34
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 145 2e-34
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 144 3e-34
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 143 6e-34
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 143 9e-34
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 143 9e-34
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 143 9e-34
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 143 9e-34
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 143 9e-34
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 142 1e-33
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 142 1e-33
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 141 3e-33
AF542390-1|AAN62841.1| 258|Homo sapiens AT03158-like protein pr... 139 1e-32
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 139 1e-32
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 139 1e-32
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 139 1e-32
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 136 1e-31
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 136 1e-31
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 136 1e-31
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 136 1e-31
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 136 1e-31
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 136 1e-31
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 136 1e-31
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 136 1e-31
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 136 1e-31
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 135 2e-31
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 131 4e-30
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 131 4e-30
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 130 6e-30
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 130 6e-30
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 130 6e-30
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 130 6e-30
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 130 6e-30
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 130 8e-30
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 130 8e-30
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 128 2e-29
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 128 2e-29
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 128 2e-29
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 128 2e-29
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 128 2e-29
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 128 2e-29
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 128 3e-29
AB183428-1|BAF73616.1| 580|Homo sapiens maternal embryonic luec... 128 3e-29
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 126 1e-28
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 126 1e-28
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 126 1e-28
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 123 1e-27
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 123 1e-27
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 123 1e-27
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 122 1e-27
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 122 1e-27
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 122 1e-27
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 122 1e-27
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 122 1e-27
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 122 1e-27
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 122 1e-27
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 122 1e-27
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 122 1e-27
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 121 3e-27
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 121 3e-27
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 121 4e-27
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 120 5e-27
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 120 5e-27
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 120 5e-27
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 120 5e-27
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 120 5e-27
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 120 5e-27
AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-depende... 120 5e-27
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 120 9e-27
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 120 9e-27
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 120 9e-27
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 120 9e-27
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 120 9e-27
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 120 9e-27
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 120 9e-27
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 119 2e-26
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 119 2e-26
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 118 2e-26
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 118 2e-26
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 118 2e-26
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 118 2e-26
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 118 2e-26
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 118 3e-26
BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing s... 118 4e-26
BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein. 118 4e-26
BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-depe... 118 4e-26
AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein. 118 4e-26
AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-depende... 118 4e-26
AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-depende... 118 4e-26
AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform pr... 118 4e-26
AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-depe... 118 4e-26
AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-depe... 118 4e-26
AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-depende... 118 4e-26
AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-depende... 118 4e-26
AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein. 118 4e-26
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 117 5e-26
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 117 5e-26
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 117 6e-26
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 117 6e-26
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 117 6e-26
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 117 6e-26
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 117 6e-26
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 117 6e-26
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 117 6e-26
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 116 8e-26
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 116 8e-26
U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein ... 116 1e-25
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 116 1e-25
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 116 1e-25
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 116 1e-25
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 116 1e-25
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 116 1e-25
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 116 1e-25
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 116 1e-25
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 116 1e-25
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 116 1e-25
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 116 1e-25
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 115 2e-25
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 115 2e-25
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 115 2e-25
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 115 2e-25
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 115 3e-25
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 115 3e-25
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 115 3e-25
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 115 3e-25
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 115 3e-25
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 115 3e-25
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 115 3e-25
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 115 3e-25
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 114 5e-25
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 114 5e-25
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 114 5e-25
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 114 5e-25
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 114 5e-25
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 114 5e-25
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 114 5e-25
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 113 6e-25
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 113 6e-25
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 113 6e-25
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 113 6e-25
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 113 6e-25
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 113 6e-25
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 113 6e-25
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 113 6e-25
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 113 6e-25
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 113 6e-25
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 113 6e-25
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 113 6e-25
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 113 6e-25
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 113 6e-25
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 113 6e-25
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 113 6e-25
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 113 6e-25
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 113 6e-25
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 113 6e-25
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 113 6e-25
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 113 6e-25
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 113 6e-25
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 113 6e-25
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 113 6e-25
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 113 6e-25
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 113 8e-25
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 113 8e-25
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 113 8e-25
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 113 8e-25
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 113 8e-25
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 112 1e-24
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 112 1e-24
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 112 1e-24
BC121188-1|AAI21189.1| 185|Homo sapiens KIAA0999 protein protein. 112 1e-24
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 112 1e-24
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 112 1e-24
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 112 2e-24
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 112 2e-24
AL713896-5|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 112 2e-24
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 112 2e-24
AL713896-3|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 112 2e-24
AL713896-2|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 112 2e-24
AL596247-5|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 112 2e-24
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 112 2e-24
AL596247-3|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 112 2e-24
AL596247-2|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 112 2e-24
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 112 2e-24
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 111 2e-24
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 111 2e-24
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 111 2e-24
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 111 2e-24
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 111 2e-24
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 111 2e-24
AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 111 2e-24
AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 111 2e-24
AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 111 2e-24
AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 111 2e-24
AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform pr... 111 2e-24
AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform pr... 111 2e-24
AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform pr... 111 2e-24
AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-depende... 111 2e-24
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 111 2e-24
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 111 2e-24
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 111 3e-24
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 111 3e-24
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 111 3e-24
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 111 3e-24
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 111 3e-24
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 111 3e-24
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 111 3e-24
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 111 3e-24
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 111 3e-24
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 111 3e-24
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 111 3e-24
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 111 3e-24
BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein. 110 6e-24
AY355461-1|AAQ84219.1| 347|Homo sapiens MNK1-like kinase 1b pro... 110 6e-24
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 110 6e-24
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 109 1e-23
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 109 1e-23
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 109 1e-23
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 109 1e-23
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 109 1e-23
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 109 1e-23
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 109 1e-23
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 109 1e-23
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 109 1e-23
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 109 1e-23
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 109 1e-23
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 109 1e-23
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 109 1e-23
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 109 1e-23
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 109 1e-23
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 109 1e-23
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 109 1e-23
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 109 1e-23
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 109 1e-23
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 109 1e-23
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 109 1e-23
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 109 2e-23
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 109 2e-23
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 108 2e-23
D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein. 108 2e-23
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 108 3e-23
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 108 3e-23
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 108 3e-23
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 108 3e-23
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 107 4e-23
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 107 4e-23
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 107 4e-23
AL136373-5|CAI14764.1| 424|Homo sapiens MAP kinase interacting ... 107 4e-23
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 107 4e-23
AB000409-1|BAA19885.1| 424|Homo sapiens MNK1 protein. 107 4e-23
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 107 5e-23
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 107 5e-23
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 107 5e-23
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 107 5e-23
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 107 5e-23
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 107 5e-23
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 107 5e-23
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 107 5e-23
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 107 5e-23
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 107 5e-23
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 107 7e-23
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 107 7e-23
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 107 7e-23
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 107 7e-23
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 106 9e-23
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 106 9e-23
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 106 9e-23
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 106 9e-23
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 106 9e-23
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 106 9e-23
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 106 9e-23
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 106 9e-23
AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting ... 106 9e-23
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 106 9e-23
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 106 9e-23
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 106 9e-23
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 106 9e-23
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 106 9e-23
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 106 9e-23
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 106 9e-23
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 106 1e-22
BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein. 106 1e-22
AL713896-1|CAI13787.1| 453|Homo sapiens calcium/calmodulin-depe... 106 1e-22
AL596247-1|CAI13964.1| 453|Homo sapiens calcium/calmodulin-depe... 106 1e-22
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 105 2e-22
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 105 2e-22
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 105 2e-22
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 105 2e-22
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 105 2e-22
L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-depend... 105 2e-22
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 105 2e-22
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 105 2e-22
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 105 2e-22
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 104 4e-22
AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein pr... 104 4e-22
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 103 8e-22
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 103 8e-22
U77735-1|AAC78506.1| 334|Homo sapiens pim-2 protooncogene homol... 103 8e-22
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 103 8e-22
BC018111-1|AAH18111.1| 311|Homo sapiens pim-2 oncogene protein. 103 8e-22
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 103 8e-22
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 103 8e-22
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 103 8e-22
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 103 8e-22
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 103 8e-22
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 103 8e-22
AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein. 103 8e-22
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 103 8e-22
AB042425-1|BAA95613.1| 311|Homo sapiens pim-2 protooncogene hom... 103 8e-22
AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase... 103 8e-22
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 103 1e-21
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 103 1e-21
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 103 1e-21
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 103 1e-21
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 103 1e-21
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 103 1e-21
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 103 1e-21
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 103 1e-21
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 103 1e-21
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 103 1e-21
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 103 1e-21
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 103 1e-21
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 103 1e-21
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 103 1e-21
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 103 1e-21
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 103 1e-21
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 103 1e-21
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 103 1e-21
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 103 1e-21
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 103 1e-21
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 103 1e-21
CR536608-1|CAO03523.1| 326|Homo sapiens pim-3 oncogene protein. 102 1e-21
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 102 1e-21
BX539320-1|CAO03581.1| 326|Homo sapiens pim-3 oncogene protein. 102 1e-21
BC141855-1|AAI41856.1| 326|Homo sapiens pim-3 oncogene protein. 102 1e-21
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 102 1e-21
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 102 1e-21
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 102 1e-21
AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kina... 102 1e-21
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 102 1e-21
AB114795-1|BAD42438.1| 326|Homo sapiens serine/threonine kinase... 102 1e-21
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 102 2e-21
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 102 2e-21
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 102 2e-21
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 102 2e-21
AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein. 102 2e-21
AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome ... 102 2e-21
AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase... 102 2e-21
AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase... 102 2e-21
AB209553-1|BAD92790.1| 337|Homo sapiens serine/threonine protei... 102 2e-21
BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein. 101 3e-21
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 101 3e-21
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 101 4e-21
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 101 4e-21
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 101 4e-21
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 101 4e-21
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 101 4e-21
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 101 4e-21
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 101 4e-21
BC031647-1|AAH31647.1| 520|Homo sapiens calcium/calmodulin-depe... 101 4e-21
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 101 4e-21
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 101 4e-21
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 101 4e-21
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 100 6e-21
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 100 6e-21
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 100 6e-21
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 100 6e-21
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 100 6e-21
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 100 6e-21
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 100 6e-21
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 100 6e-21
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 100 6e-21
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 100 6e-21
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 100 6e-21
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 100 6e-21
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 100 6e-21
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 100 8e-21
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 100 8e-21
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 100 8e-21
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 100 8e-21
EF644172-1|ABR45718.1| 433|Homo sapiens polarization-related pr... 100 8e-21
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 100 8e-21
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 100 8e-21
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 100 8e-21
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 100 8e-21
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 100 8e-21
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 99 1e-20
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 99 1e-20
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 99 1e-20
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 100 1e-20
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 100 1e-20
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 100 1e-20
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 100 1e-20
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 100 1e-20
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 100 1e-20
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 100 1e-20
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 100 1e-20
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 100 1e-20
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 100 1e-20
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 100 1e-20
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 254 bits (623), Expect = 2e-67
Identities = 121/253 (47%), Positives = 179/253 (70%), Gaps = 3/253 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SYA VK A S+R VAIKII + +AP D+L+KFLPREIE++ L H ++I+ + ET
Sbjct: 22 SYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFET 81
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
+H +VYIVME A G LL++I+ + E R+ F QL A+ YCH+ VVHRD+KC+N
Sbjct: 82 SHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDN 141
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
LL+D NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+ D+WS
Sbjct: 142 LLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWS 201
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRV 156
+GV+LY +V G +P+DD+N ++L+ Q +++V+FPR ++ EC+ LI +L P + R+
Sbjct: 202 LGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRL 261
Query: 155 KIPQILADPWLNP 117
I +IL+ W+ P
Sbjct: 262 HIDEILSHCWMQP 274
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 254 bits (623), Expect = 2e-67
Identities = 121/253 (47%), Positives = 179/253 (70%), Gaps = 3/253 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SYA VK A S+R VAIKII + +AP D+L+KFLPREIE++ L H ++I+ + ET
Sbjct: 22 SYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFET 81
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
+H +VYIVME A G LL++I+ + E R+ F QL A+ YCH+ VVHRD+KC+N
Sbjct: 82 SHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDN 141
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
LL+D NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+ D+WS
Sbjct: 142 LLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWS 201
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRV 156
+GV+LY +V G +P+DD+N ++L+ Q +++V+FPR ++ EC+ LI +L P + R+
Sbjct: 202 LGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRL 261
Query: 155 KIPQILADPWLNP 117
I +IL+ W+ P
Sbjct: 262 HIDEILSHCWMQP 274
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 254 bits (623), Expect = 2e-67
Identities = 121/253 (47%), Positives = 179/253 (70%), Gaps = 3/253 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SYA VK A S+R VAIKII + +AP D+L+KFLPREIE++ L H ++I+ + ET
Sbjct: 22 SYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCSIIKTYEIFET 81
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
+H +VYIVME A G LL++I+ + E R+ F QL A+ YCH+ VVHRD+KC+N
Sbjct: 82 SHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDN 141
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
LL+D NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+ D+WS
Sbjct: 142 LLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWS 201
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRV 156
+GV+LY +V G +P+DD+N ++L+ Q +++V+FPR ++ EC+ LI +L P + R+
Sbjct: 202 LGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRL 261
Query: 155 KIPQILADPWLNP 117
I +IL+ W+ P
Sbjct: 262 HIDEILSHCWMQP 274
>CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein.
Length = 358
Score = 247 bits (605), Expect = 4e-65
Identities = 113/253 (44%), Positives = 175/253 (69%), Gaps = 3/253 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SYA VK A S+R VA+KII + + P D++++FLPRE++++ + H ++I+ + ET
Sbjct: 22 SYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFET 81
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
+ R+YI+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCEN
Sbjct: 82 SDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCEN 141
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
LL+D NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS
Sbjct: 142 LLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWS 201
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRV 156
+GV+LY +V G +P+DD++ ++L+ Q +++V FPR ++ EC+ LI R+L P + R+
Sbjct: 202 LGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRL 261
Query: 155 KIPQILADPWLNP 117
I +IL+ WL P
Sbjct: 262 HIDEILSHSWLQP 274
>BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 247 bits (605), Expect = 4e-65
Identities = 113/253 (44%), Positives = 175/253 (69%), Gaps = 3/253 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SYA VK A S+R VA+KII + + P D++++FLPRE++++ + H ++I+ + ET
Sbjct: 22 SYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFET 81
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
+ R+YI+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCEN
Sbjct: 82 SDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCEN 141
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
LL+D NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS
Sbjct: 142 LLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWS 201
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRV 156
+GV+LY +V G +P+DD++ ++L+ Q +++V FPR ++ EC+ LI R+L P + R+
Sbjct: 202 LGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRL 261
Query: 155 KIPQILADPWLNP 117
I +IL+ WL P
Sbjct: 262 HIDEILSHSWLQP 274
>AF362953-1|AAK98531.1| 358|Homo sapiens testis specific
serine/threonine kinase 2 protein.
Length = 358
Score = 247 bits (605), Expect = 4e-65
Identities = 113/253 (44%), Positives = 175/253 (69%), Gaps = 3/253 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SYA VK A S+R VA+KII + + P D++++FLPRE++++ + H ++I+ + ET
Sbjct: 22 SYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFET 81
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
+ R+YI+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCEN
Sbjct: 82 SDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCEN 141
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
LL+D NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS
Sbjct: 142 LLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWS 201
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRV 156
+GV+LY +V G +P+DD++ ++L+ Q +++V FPR ++ EC+ LI R+L P + R+
Sbjct: 202 LGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRL 261
Query: 155 KIPQILADPWLNP 117
I +IL+ WL P
Sbjct: 262 HIDEILSHSWLQP 274
>AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 247 bits (605), Expect = 4e-65
Identities = 113/253 (44%), Positives = 175/253 (69%), Gaps = 3/253 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SYA VK A S+R VA+KII + + P D++++FLPRE++++ + H ++I+ + ET
Sbjct: 22 SYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDILATVNHGSIIKTYEIFET 81
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
+ R+YI+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCEN
Sbjct: 82 SDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCEN 141
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
LL+D NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS
Sbjct: 142 LLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWS 201
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRV 156
+GV+LY +V G +P+DD++ ++L+ Q +++V FPR ++ EC+ LI R+L P + R+
Sbjct: 202 LGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRL 261
Query: 155 KIPQILADPWLNP 117
I +IL+ WL P
Sbjct: 262 HIDEILSHSWLQP 274
>AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine
kinase 4 protein.
Length = 328
Score = 241 bits (590), Expect = 2e-63
Identities = 122/261 (46%), Positives = 167/261 (63%), Gaps = 13/261 (4%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SY +V A + VA+KIISK +A DYL KFLPREI+V+K L+H+ LI F +AIE+
Sbjct: 35 SYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIES 94
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
T RVYI++E A+ G +L+ I++ E +WF QL + Y H + +VHRD+K ENL
Sbjct: 95 TSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENL 154
Query: 506 LMDHGLNIKLSDFGFARGHMKPKN------------GVFA-LSETFCGSYAYASPEILKG 366
L+D N+K+SDFGFA+ M P N F+ LS+T+CGS+AYA PEIL+G
Sbjct: 155 LLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRG 212
Query: 365 VPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLIT 186
+PY P SD WSMGV+LY +V LPFDDTN +LL++ Q +V+FP +S EC+ LI
Sbjct: 213 LPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLIL 272
Query: 185 RILAPLKMRVKIPQILADPWL 123
++L R I I+ D W+
Sbjct: 273 QMLRQATKRATILDIIKDSWV 293
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 234 bits (572), Expect = 4e-61
Identities = 112/250 (44%), Positives = 171/250 (68%), Gaps = 2/250 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+ L H+N+I+ + +E+
Sbjct: 20 TYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLES 79
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
++ +VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN
Sbjct: 80 ADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCEN 139
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
L+ G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWS
Sbjct: 140 ALLQ-GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWS 195
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAP-LKMRVK 153
MGVVLY ++ LPFDDT+ ++L Q Q VSFP +SA+C+ L+ R+L P + +R
Sbjct: 196 MGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPS 255
Query: 152 IPQILADPWL 123
I ++ PWL
Sbjct: 256 IEEVSWHPWL 265
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 234 bits (572), Expect = 4e-61
Identities = 112/250 (44%), Positives = 171/250 (68%), Gaps = 2/250 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+ L H+N+I+ + +E+
Sbjct: 20 TYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLES 79
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
++ +VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN
Sbjct: 80 ADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCEN 139
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
L+ G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWS
Sbjct: 140 ALLQ-GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWS 195
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAP-LKMRVK 153
MGVVLY ++ LPFDDT+ ++L Q Q VSFP +SA+C+ L+ R+L P + +R
Sbjct: 196 MGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPS 255
Query: 152 IPQILADPWL 123
I ++ PWL
Sbjct: 256 IEEVSWHPWL 265
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 234 bits (572), Expect = 4e-61
Identities = 112/250 (44%), Positives = 171/250 (68%), Gaps = 2/250 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+ L H+N+I+ + +E+
Sbjct: 20 TYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLES 79
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
++ +VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN
Sbjct: 80 ADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCEN 139
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
L+ G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWS
Sbjct: 140 ALLQ-GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWS 195
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAP-LKMRVK 153
MGVVLY ++ LPFDDT+ ++L Q Q VSFP +SA+C+ L+ R+L P + +R
Sbjct: 196 MGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPS 255
Query: 152 IPQILADPWL 123
I ++ PWL
Sbjct: 256 IEEVSWHPWL 265
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 234 bits (572), Expect = 4e-61
Identities = 112/250 (44%), Positives = 171/250 (68%), Gaps = 2/250 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+ L H+N+I+ + +E+
Sbjct: 20 TYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLES 79
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
++ +VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN
Sbjct: 80 ADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCEN 139
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
L+ G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWS
Sbjct: 140 ALLQ-GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWS 195
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAP-LKMRVK 153
MGVVLY ++ LPFDDT+ ++L Q Q VSFP +SA+C+ L+ R+L P + +R
Sbjct: 196 MGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPS 255
Query: 152 IPQILADPWL 123
I ++ PWL
Sbjct: 256 IEEVSWHPWL 265
>AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens
cDNA FLJ29008 fis, clone TST06032. ).
Length = 338
Score = 231 bits (565), Expect = 2e-60
Identities = 123/271 (45%), Positives = 167/271 (61%), Gaps = 23/271 (8%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SY +V A + VA+KIISK +A DYL KFLPREI+V+K L+H+ LI F +AIE+
Sbjct: 35 SYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIES 94
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVH-------- 531
T RVYI++E A+ G +L+ IR+ E +WF QL + Y H + +VH
Sbjct: 95 TSRVYIILELAQGGDVLEWIRRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSA 154
Query: 530 --RDIKCENLLMDHGLNIKLSDFGFARGHMKPKN------------GVFA-LSETFCGSY 396
RD+K ENLL+D N+K+SDFGFA+ M P N F+ LS+T+CGS+
Sbjct: 155 AGRDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHLSQTYCGSF 212
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 216
AYA PEIL+G+PY P SD WSMGV+LY +V LPFDDTN +LL++ Q +V+FP
Sbjct: 213 AYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHT 272
Query: 215 VSAECRKLITRILAPLKMRVKIPQILADPWL 123
+S EC+ LI ++L R I I+ D W+
Sbjct: 273 ISQECKNLILQMLRQATKRATILDIIKDSWV 303
>BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein.
Length = 252
Score = 199 bits (486), Expect = 9e-51
Identities = 99/219 (45%), Positives = 139/219 (63%), Gaps = 13/219 (5%)
Frame = -3
Query: 740 VKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAV 561
+K L+H+ LI F +AIE+T RVYI++E A+ G +L+ I++ E +WF QL +
Sbjct: 1 MKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGI 60
Query: 560 DYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKN------------GVFA-L 420
Y H + +VHRD+K ENLL+D N+K+SDFGFA+ M P N F+ L
Sbjct: 61 AYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHL 118
Query: 419 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK 240
S+T+CGS+AYA PEIL+G+PY P SD WSMGV+LY +V LPFDDTN +LL++ Q +
Sbjct: 119 SQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKE 178
Query: 239 VSFPREPKVSAECRKLITRILAPLKMRVKIPQILADPWL 123
V+FP +S EC+ LI ++L R I I+ D W+
Sbjct: 179 VTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWV 217
>BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine
kinase 6 protein.
Length = 273
Score = 197 bits (481), Expect = 4e-50
Identities = 102/251 (40%), Positives = 157/251 (62%), Gaps = 3/251 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SY+ VKVA+S ++ VAIK++ + +AP D++ KFLPRE+ +++G++H +++ + IE
Sbjct: 22 SYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEV 81
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
+ ++YIVME A LL ++++ I + R F Q+ AV Y H+ +VHRD+KCEN
Sbjct: 82 CNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCEN 140
Query: 509 LLMD-HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 333
+L+ +KL+DFGF R +G LS T+CGS AYASPE+L G+PY P+ DVW
Sbjct: 141 VLLSPDERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVW 196
Query: 332 SMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRV 156
SMGVVLY +V G +PFDD++ L ++ + V +P ++S C+ LI +L R
Sbjct: 197 SMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQFSPSARP 256
Query: 155 KIPQILADPWL 123
Q+ + WL
Sbjct: 257 SAGQVARNCWL 267
>AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protein
kinase SSTK protein.
Length = 273
Score = 197 bits (481), Expect = 4e-50
Identities = 102/251 (40%), Positives = 157/251 (62%), Gaps = 3/251 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SY+ VKVA+S ++ VAIK++ + +AP D++ KFLPRE+ +++G++H +++ + IE
Sbjct: 22 SYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEV 81
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
+ ++YIVME A LL ++++ I + R F Q+ AV Y H+ +VHRD+KCEN
Sbjct: 82 CNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCEN 140
Query: 509 LLMD-HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 333
+L+ +KL+DFGF R +G LS T+CGS AYASPE+L G+PY P+ DVW
Sbjct: 141 VLLSPDERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVW 196
Query: 332 SMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRV 156
SMGVVLY +V G +PFDD++ L ++ + V +P ++S C+ LI +L R
Sbjct: 197 SMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQFSPSARP 256
Query: 155 KIPQILADPWL 123
Q+ + WL
Sbjct: 257 SAGQVARNCWL 267
>AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens
cDNA FLJ24002 fis, clone KAIA4350, highly similar to
Homo sapiens serine/threonine protein kinase SSTK
(SSTK). ).
Length = 406
Score = 196 bits (477), Expect = 1e-49
Identities = 100/244 (40%), Positives = 156/244 (63%), Gaps = 4/244 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
SY+ VKVA+S ++ VAIK++ + +AP D++ KFLPRE+ +++G++H +++ + IE
Sbjct: 22 SYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILRGVRHPHIVHVFEFIEV 81
Query: 686 TH-RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
+ ++YIVME A LL ++++ I + R F Q+ AV Y H+ +VHRD+KCEN
Sbjct: 82 CNGKLYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCEN 140
Query: 509 LLMD-HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 333
+L+ +KL+DFGF R +G LS T+CGS AYASPE+L G+PY P+ DVW
Sbjct: 141 VLLSPDERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVW 196
Query: 332 SMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMR 159
SMGVVLY +V G +PFDD++ L ++ + V +P ++S C+ LI A P++
Sbjct: 197 SMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAEAAAVQPVRQA 256
Query: 158 VKIP 147
++ P
Sbjct: 257 LRGP 260
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 189 bits (461), Expect = 1e-47
Identities = 104/265 (39%), Positives = 158/265 (59%), Gaps = 3/265 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VAIKII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 66 NFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET 124
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y++MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 125 EKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENL 184
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 185 LLDADMNIKIADFGFSN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 239
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ R +L P+K R
Sbjct: 240 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKRFLVLNPIK-RG 296
Query: 155 KIPQILADPWLNPNQQSKHDETDLQ 81
+ QI+ D W+N + H+E +L+
Sbjct: 297 TLEQIMKDRWIN----AGHEEDELK 317
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 189 bits (461), Expect = 1e-47
Identities = 104/265 (39%), Positives = 158/265 (59%), Gaps = 3/265 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VAIKII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 66 NFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET 124
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y++MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 125 QKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENL 184
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 185 LLDADMNIKIADFGFSN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 239
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ R +L P+K R
Sbjct: 240 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKRFLVLNPIK-RG 296
Query: 155 KIPQILADPWLNPNQQSKHDETDLQ 81
+ QI+ D W+N + H+E +L+
Sbjct: 297 TLEQIMKDRWIN----AGHEEDELK 317
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 189 bits (461), Expect = 1e-47
Identities = 104/265 (39%), Positives = 158/265 (59%), Gaps = 3/265 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VAIKII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 66 NFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET 124
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y++MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 125 EKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENL 184
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 185 LLDADMNIKIADFGFSN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 239
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ R +L P+K R
Sbjct: 240 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKRFLVLNPIK-RG 296
Query: 155 KIPQILADPWLNPNQQSKHDETDLQ 81
+ QI+ D W+N + H+E +L+
Sbjct: 297 TLEQIMKDRWIN----AGHEEDELK 317
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 189 bits (461), Expect = 1e-47
Identities = 104/265 (39%), Positives = 158/265 (59%), Gaps = 3/265 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VAIKII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 66 NFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET 124
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y++MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 125 EKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENL 184
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 185 LLDADMNIKIADFGFSN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 239
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ R +L P+K R
Sbjct: 240 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKRFLVLNPIK-RG 296
Query: 155 KIPQILADPWLNPNQQSKHDETDLQ 81
+ QI+ D W+N + H+E +L+
Sbjct: 297 TLEQIMKDRWIN----AGHEEDELK 317
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 189 bits (461), Expect = 1e-47
Identities = 104/265 (39%), Positives = 158/265 (59%), Gaps = 3/265 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VAIKII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 66 NFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET 124
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y++MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 125 EKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENL 184
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 185 LLDADMNIKIADFGFSN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 239
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ R +L P+K R
Sbjct: 240 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKRFLVLNPIK-RG 296
Query: 155 KIPQILADPWLNPNQQSKHDETDLQ 81
+ QI+ D W+N + H+E +L+
Sbjct: 297 TLEQIMKDRWIN----AGHEEDELK 317
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 188 bits (459), Expect = 2e-47
Identities = 100/252 (39%), Positives = 151/252 (59%), Gaps = 3/252 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VAIKII K Q L+K RE+ ++KGL H N+++ + IET
Sbjct: 69 NFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIET 127
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 128 EKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENL 187
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+
Sbjct: 188 LLDAEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSL 242
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R
Sbjct: 243 GVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RC 299
Query: 155 KIPQILADPWLN 120
+ QI+ D W+N
Sbjct: 300 TLEQIMKDKWIN 311
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 188 bits (459), Expect = 2e-47
Identities = 100/252 (39%), Positives = 151/252 (59%), Gaps = 3/252 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VAIKII K Q L+K RE+ ++KGL H N+++ + IET
Sbjct: 69 NFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIET 127
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 128 EKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENL 187
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+
Sbjct: 188 LLDAEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSL 242
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R
Sbjct: 243 GVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RC 299
Query: 155 KIPQILADPWLN 120
+ QI+ D W+N
Sbjct: 300 TLEQIMKDKWIN 311
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 188 bits (459), Expect = 2e-47
Identities = 100/252 (39%), Positives = 151/252 (59%), Gaps = 3/252 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VAIKII K Q L+K RE+ ++KGL H N+++ + IET
Sbjct: 69 NFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIET 127
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 128 EKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENL 187
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+
Sbjct: 188 LLDAEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSL 242
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R
Sbjct: 243 GVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RC 299
Query: 155 KIPQILADPWLN 120
+ QI+ D W+N
Sbjct: 300 TLEQIMKDKWIN 311
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 188 bits (459), Expect = 2e-47
Identities = 100/252 (39%), Positives = 151/252 (59%), Gaps = 3/252 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VAIKII K Q L+K RE+ ++KGL H N+++ + IET
Sbjct: 70 NFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIET 128
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 129 EKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENL 188
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+
Sbjct: 189 LLDAEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSL 243
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R
Sbjct: 244 GVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RC 300
Query: 155 KIPQILADPWLN 120
+ QI+ D W+N
Sbjct: 301 TLEQIMKDKWIN 312
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 188 bits (458), Expect = 2e-47
Identities = 103/269 (38%), Positives = 159/269 (59%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 70 NFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET 128
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 129 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENL 188
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 189 LLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 243
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L P+K R
Sbjct: 244 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RG 300
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H+E +L+ + +
Sbjct: 301 SLEQIMKDRWMNVG----HEEEELKPYTE 325
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 188 bits (458), Expect = 2e-47
Identities = 103/269 (38%), Positives = 159/269 (59%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 70 NFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET 128
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 129 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENL 188
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 189 LLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 243
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L P+K R
Sbjct: 244 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RG 300
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H+E +L+ + +
Sbjct: 301 SLEQIMKDRWMNVG----HEEEELKPYTE 325
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 188 bits (458), Expect = 2e-47
Identities = 103/269 (38%), Positives = 159/269 (59%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 70 NFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET 128
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 129 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENL 188
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 189 LLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 243
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L P+K R
Sbjct: 244 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RG 300
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H+E +L+ + +
Sbjct: 301 SLEQIMKDRWMNVG----HEEEELKPYTE 325
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 188 bits (458), Expect = 2e-47
Identities = 103/269 (38%), Positives = 159/269 (59%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 70 NFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET 128
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 129 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENL 188
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 189 LLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 243
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L P+K R
Sbjct: 244 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RG 300
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H+E +L+ + +
Sbjct: 301 SLEQIMKDRWMNVG----HEEEELKPYTE 325
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 187 bits (455), Expect = 5e-47
Identities = 100/250 (40%), Positives = 149/250 (59%), Gaps = 3/250 (1%)
Frame = -3
Query: 860 ATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH 681
A VK+A +VAIKII K Q L+K RE+ ++KGL H N+++ + IET
Sbjct: 71 AKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIETEK 129
Query: 680 RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 501
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+
Sbjct: 130 TLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLL 189
Query: 500 DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 321
D NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV
Sbjct: 190 DAEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGV 244
Query: 320 VLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKI 150
+LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R +
Sbjct: 245 ILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTL 301
Query: 149 PQILADPWLN 120
QI+ D W+N
Sbjct: 302 EQIMKDKWIN 311
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 187 bits (455), Expect = 5e-47
Identities = 100/250 (40%), Positives = 149/250 (59%), Gaps = 3/250 (1%)
Frame = -3
Query: 860 ATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH 681
A VK+A +VAIKII K Q L+K RE+ ++KGL H N+++ + IET
Sbjct: 71 AKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIETEK 129
Query: 680 RVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 501
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+
Sbjct: 130 TLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLL 189
Query: 500 DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 321
D NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV
Sbjct: 190 DAEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGV 244
Query: 320 VLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKI 150
+LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R +
Sbjct: 245 ILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTL 301
Query: 149 PQILADPWLN 120
QI+ D W+N
Sbjct: 302 EQIMKDKWIN 311
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 186 bits (452), Expect = 1e-46
Identities = 102/269 (37%), Positives = 156/269 (57%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 30 NFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIET 88
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 89 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENL 148
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 149 LLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 203
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R
Sbjct: 204 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RG 260
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H++ +L+ + +
Sbjct: 261 TLEQIMKDRWMNVG----HEDDELKPYVE 285
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 186 bits (452), Expect = 1e-46
Identities = 102/269 (37%), Positives = 156/269 (57%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 30 NFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIET 88
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 89 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENL 148
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 149 LLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 203
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R
Sbjct: 204 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RG 260
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H++ +L+ + +
Sbjct: 261 TLEQIMKDRWMNVG----HEDDELKPYVE 285
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 186 bits (452), Expect = 1e-46
Identities = 102/269 (37%), Positives = 156/269 (57%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 63 NFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIET 121
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 122 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENL 181
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 182 LLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 236
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R
Sbjct: 237 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RG 293
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H++ +L+ + +
Sbjct: 294 TLEQIMKDRWMNVG----HEDDELKPYVE 318
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 186 bits (452), Expect = 1e-46
Identities = 102/269 (37%), Positives = 156/269 (57%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 53 NFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIET 111
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 112 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENL 171
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 172 LLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 226
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R
Sbjct: 227 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RG 283
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H++ +L+ + +
Sbjct: 284 TLEQIMKDRWMNVG----HEDDELKPYVE 308
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 186 bits (452), Expect = 1e-46
Identities = 102/269 (37%), Positives = 156/269 (57%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 30 NFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIET 88
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 89 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENL 148
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 149 LLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 203
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R
Sbjct: 204 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RG 260
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H++ +L+ + +
Sbjct: 261 TLEQIMKDRWMNVG----HEDDELKPYVE 285
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 186 bits (452), Expect = 1e-46
Identities = 102/269 (37%), Positives = 156/269 (57%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 63 NFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLF-REVRIMKVLNHPNIVKLFEVIET 121
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 122 EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENL 181
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 182 LLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 236
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R
Sbjct: 237 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RG 293
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H++ +L+ + +
Sbjct: 294 TLEQIMKDRWMNVG----HEDDELKPYVE 318
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 184 bits (447), Expect = 5e-46
Identities = 103/250 (41%), Positives = 148/250 (59%), Gaps = 2/250 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+ +VAIKII K Q L+K RE++++K L H ++I+ Q +ET
Sbjct: 30 NFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPHIIKLYQVMET 88
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENL
Sbjct: 89 KSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENL 148
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y D+WSM
Sbjct: 149 LLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSM 203
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--ILAPLKMRVK 153
GVVLY +V G LPFD +L+Q + F +S +C LI R +L P K R+
Sbjct: 204 GVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK-RLT 261
Query: 152 IPQILADPWL 123
I QI W+
Sbjct: 262 IAQIKEHKWM 271
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 184 bits (447), Expect = 5e-46
Identities = 103/250 (41%), Positives = 148/250 (59%), Gaps = 2/250 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+ +VAIKII K Q L+K RE++++K L H ++I+ Q +ET
Sbjct: 30 NFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPHIIKLYQVMET 88
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENL
Sbjct: 89 KSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENL 148
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y D+WSM
Sbjct: 149 LLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSM 203
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--ILAPLKMRVK 153
GVVLY +V G LPFD +L+Q + F +S +C LI R +L P K R+
Sbjct: 204 GVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK-RLT 261
Query: 152 IPQILADPWL 123
I QI W+
Sbjct: 262 IAQIKEHKWM 271
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 184 bits (447), Expect = 5e-46
Identities = 103/250 (41%), Positives = 148/250 (59%), Gaps = 2/250 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+ +VAIKII K Q L+K RE++++K L H ++I+ Q +ET
Sbjct: 28 NFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPHIIKLYQVMET 86
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENL
Sbjct: 87 KSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENL 146
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y D+WSM
Sbjct: 147 LLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSM 201
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--ILAPLKMRVK 153
GVVLY +V G LPFD +L+Q + F +S +C LI R +L P K R+
Sbjct: 202 GVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK-RLT 259
Query: 152 IPQILADPWL 123
I QI W+
Sbjct: 260 IAQIKEHKWM 269
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 184 bits (447), Expect = 5e-46
Identities = 103/250 (41%), Positives = 148/250 (59%), Gaps = 2/250 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+ +VAIKII K Q L+K RE++++K L H ++I+ Q +ET
Sbjct: 54 NFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIY-REVQIMKMLDHPHIIKLYQVMET 112
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENL
Sbjct: 113 KSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENL 172
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y D+WSM
Sbjct: 173 LLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSM 227
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--ILAPLKMRVK 153
GVVLY +V G LPFD +L+Q + F +S +C LI R +L P K R+
Sbjct: 228 GVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK-RLT 285
Query: 152 IPQILADPWL 123
I QI W+
Sbjct: 286 IAQIKEHKWM 295
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 183 bits (445), Expect = 9e-46
Identities = 102/251 (40%), Positives = 152/251 (60%), Gaps = 3/251 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A QVAIKII K + L+K RE++++K L H ++I+ Q +ET
Sbjct: 37 NFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMET 95
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENL
Sbjct: 96 KDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENL 155
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D ++IKL+DFGF + K+G LS T+CGS YA+PE+ +G Y D+WS+
Sbjct: 156 LLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSL 210
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 156
GVVLY +V G LPFD N L ++V + + P +S +C LI R+L P + R+
Sbjct: 211 GVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIRRMLVVDPAR-RI 267
Query: 155 KIPQILADPWL 123
I QI W+
Sbjct: 268 TIAQIRQHRWM 278
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 183 bits (445), Expect = 9e-46
Identities = 102/251 (40%), Positives = 152/251 (60%), Gaps = 3/251 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A QVAIKII K + L+K RE++++K L H ++I+ Q +ET
Sbjct: 18 NFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMET 76
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENL
Sbjct: 77 KDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENL 136
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D ++IKL+DFGF + K+G LS T+CGS YA+PE+ +G Y D+WS+
Sbjct: 137 LLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSL 191
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 156
GVVLY +V G LPFD N L ++V + + P +S +C LI R+L P + R+
Sbjct: 192 GVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIRRMLVVDPAR-RI 248
Query: 155 KIPQILADPWL 123
I QI W+
Sbjct: 249 TIAQIRQHRWM 259
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 183 bits (445), Expect = 9e-46
Identities = 102/251 (40%), Positives = 152/251 (60%), Gaps = 3/251 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A QVAIKII K + L+K RE++++K L H ++I+ Q +ET
Sbjct: 37 NFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMET 95
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENL
Sbjct: 96 KDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENL 155
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D ++IKL+DFGF + K+G LS T+CGS YA+PE+ +G Y D+WS+
Sbjct: 156 LLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSL 210
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 156
GVVLY +V G LPFD N L ++V + + P +S +C LI R+L P + R+
Sbjct: 211 GVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIRRMLVVDPAR-RI 267
Query: 155 KIPQILADPWL 123
I QI W+
Sbjct: 268 TIAQIRQHRWM 278
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 183 bits (445), Expect = 9e-46
Identities = 98/261 (37%), Positives = 146/261 (55%), Gaps = 1/261 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y VK A+ VAIK I K + + + REIE++ L H ++I + E
Sbjct: 102 TYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFEN 161
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++ I+MEYA G L D I + + + E R +F+Q+V AV YCH+ GVVHRD+K EN+
Sbjct: 162 KDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENI 221
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D NIK++DFG + + K K +TFCGS YASPEI+ G PYR + D W++
Sbjct: 222 LLDDNCNIKIADFGLSNLYQKDK-----FLQTFCGSPLYASPEIVNGRPYRGPEVDSWAL 276
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLIT-RILAPLKMRVKI 150
GV+LY +VYG +PFD ++ L++Q+ + REP ++ R LI ++ R I
Sbjct: 277 GVLLYTLVYGTMPFDGFDHKNLIRQISS--GEYREPTQPSDARGLIRWMLMVNPDRRATI 334
Query: 149 PQILADPWLNPNQQSKHDETD 87
I W+N +S + D
Sbjct: 335 EDIANHWWVNWGYKSSVCDCD 355
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 177 bits (430), Expect = 6e-44
Identities = 102/254 (40%), Positives = 152/254 (59%), Gaps = 6/254 (2%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A QVAIKII K + L+K RE++++K L H ++I+ Q +ET
Sbjct: 37 NFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMET 95
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENL
Sbjct: 96 KDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENL 155
Query: 506 LMDHGLNIKLS---DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L+D ++IKL+ DFGF + K+G LS T+CGS YA+PE+ +G Y D+
Sbjct: 156 LLDGNMDIKLAGTEDFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDI 210
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLK 165
WS+GVVLY +V G LPFD N L ++V + + P +S +C LI R+L P +
Sbjct: 211 WSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIRRMLVVDPAR 268
Query: 164 MRVKIPQILADPWL 123
R+ I QI W+
Sbjct: 269 -RITIAQIRQHRWM 281
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 176 bits (428), Expect = 1e-43
Identities = 93/249 (37%), Positives = 140/249 (56%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y VK A VAIK I K + + + REIE++ L H ++I + E
Sbjct: 63 TYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFEN 121
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ ++ IVMEYA G L D I + Q + E R +F+Q+V AV YCH+ VVHRD+K EN+
Sbjct: 122 SSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENI 181
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D NIK++DFG + + + K +TFCGS YASPEI+ G PY + D WS+
Sbjct: 182 LLDANGNIKIADFGLSNLYHQGK-----FLQTFCGSPLYASPEIVNGKPYTGPEVDSWSL 236
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPLKMRVKIP 147
GV+LY +V+G +PFD ++ L+KQ+ N ++ PK S C + ++ R +
Sbjct: 237 GVLLYILVHGTMPFDGHDHKILVKQISNG-AYREPPKPSDACGLIRWLLMVNPTRRATLE 295
Query: 146 QILADPWLN 120
+ + W+N
Sbjct: 296 DVASHWWVN 304
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 176 bits (428), Expect = 1e-43
Identities = 93/249 (37%), Positives = 140/249 (56%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y VK A VAIK I K + + + REIE++ L H ++I + E
Sbjct: 63 TYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPHIIAIHEVFEN 121
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ ++ IVMEYA G L D I + Q + E R +F+Q+V AV YCH+ VVHRD+K EN+
Sbjct: 122 SSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENI 181
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D NIK++DFG + + + K +TFCGS YASPEI+ G PY + D WS+
Sbjct: 182 LLDANGNIKIADFGLSNLYHQGK-----FLQTFCGSPLYASPEIVNGKPYTGPEVDSWSL 236
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPLKMRVKIP 147
GV+LY +V+G +PFD ++ L+KQ+ N ++ PK S C + ++ R +
Sbjct: 237 GVLLYILVHGTMPFDGHDHKILVKQISNG-AYREPPKPSDACGLIRWLLMVNPTRRATLE 295
Query: 146 QILADPWLN 120
+ + W+N
Sbjct: 296 DVASHWWVN 304
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 175 bits (427), Expect = 1e-43
Identities = 103/251 (41%), Positives = 144/251 (57%), Gaps = 3/251 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK A+ +VAIKII K Q + LKK RE++++K L H ++IR Q +ET
Sbjct: 18 NFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMET 76
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+V EYA G + D + + E RR FKQ+V AV +CH R +VHRD+K ENL
Sbjct: 77 ERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENL 136
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D LNIK++DFGF+ + L +T+CGS YA+PE+ +G Y D+WS+
Sbjct: 137 LLDANLNIKIADFGFSNLFTPGQ-----LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSL 191
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GVVLY +V G LPFD + L +V K P +S EC LI +L P K R+
Sbjct: 192 GVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPF--FMSTECEHLIRHMLVLDPNK-RL 248
Query: 155 KIPQILADPWL 123
+ QI W+
Sbjct: 249 SMEQICKHKWM 259
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 175 bits (427), Expect = 1e-43
Identities = 103/251 (41%), Positives = 144/251 (57%), Gaps = 3/251 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK A+ +VAIKII K Q + LKK RE++++K L H ++IR Q +ET
Sbjct: 126 NFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPHIIRLYQVMET 184
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+V EYA G + D + + E RR FKQ+V AV +CH R +VHRD+K ENL
Sbjct: 185 ERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENL 244
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D LNIK++DFGF+ + L +T+CGS YA+PE+ +G Y D+WS+
Sbjct: 245 LLDANLNIKIADFGFSNLFTPGQ-----LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSL 299
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRV 156
GVVLY +V G LPFD + L +V K P +S EC LI +L P K R+
Sbjct: 300 GVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPF--FMSTECEHLIRHMLVLDPNK-RL 356
Query: 155 KIPQILADPWL 123
+ QI W+
Sbjct: 357 SMEQICKHKWM 367
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 134 bits (325), Expect(2) = 5e-43
Identities = 70/179 (39%), Positives = 107/179 (59%), Gaps = 3/179 (1%)
Frame = -3
Query: 647 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 468
G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D NIK++DF
Sbjct: 171 GEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADF 230
Query: 467 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 288
GF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+LY +V G LP
Sbjct: 231 GFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLP 285
Query: 287 FDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIPQILADPWLN 120
FD N +L ++V + K P +S +C ++ R +L P K R + QI+ D W+N
Sbjct: 286 FDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLEQIMKDKWIN 341
Score = 60.5 bits (140), Expect(2) = 5e-43
Identities = 31/74 (41%), Positives = 45/74 (60%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VAIKII K Q L+K RE+ ++KGL H N+++ + IET
Sbjct: 69 NFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLF-REVRIMKGLNHPNIVKLFEVIET 127
Query: 686 THRVYIVMEYAENG 645
+Y+VMEYA G
Sbjct: 128 EKTLYLVMEYASAG 141
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 167 bits (405), Expect = 6e-41
Identities = 104/288 (36%), Positives = 157/288 (54%), Gaps = 26/288 (9%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VAIKII K Q L+K RE+ ++K L H N+++ + IET
Sbjct: 66 NFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLF-REVRIMKILNHPNIVKLFEVIET 124
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ----------------------- 576
+Y++MEYA G + D + + E R F+Q
Sbjct: 125 EKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLMFTF 184
Query: 575 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 396
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ V +TFCGS
Sbjct: 185 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT-----VGGKLDTFCGSP 239
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 219
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 240 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 297
Query: 218 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 81
+S +C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 298 YMSTDCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 340
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 163 bits (395), Expect = 1e-39
Identities = 91/249 (36%), Positives = 138/249 (55%), Gaps = 2/249 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+A VK+A VAIKI+ K D + + EIE +K L+H+++ + +ET
Sbjct: 27 FAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETA 84
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
+++++V+EY G L D I + E R F+Q+V AV Y H +G HRD+K ENLL
Sbjct: 85 NKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLL 144
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
D +KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 145 FDEYHKLKLIDFGLC---AKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMG 201
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 150
++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R+ +
Sbjct: 202 ILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISM 259
Query: 149 PQILADPWL 123
+L PW+
Sbjct: 260 KNLLNHPWI 268
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 163 bits (395), Expect = 1e-39
Identities = 91/249 (36%), Positives = 138/249 (55%), Gaps = 2/249 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+A VK+A VAIKI+ K D + + EIE +K L+H+++ + +ET
Sbjct: 22 FAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETA 79
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
+++++V+EY G L D I + E R F+Q+V AV Y H +G HRD+K ENLL
Sbjct: 80 NKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLL 139
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
D +KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 140 FDEYHKLKLIDFGLC---AKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMG 196
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 150
++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R+ +
Sbjct: 197 ILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISM 254
Query: 149 PQILADPWL 123
+L PW+
Sbjct: 255 KNLLNHPWI 263
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 163 bits (395), Expect = 1e-39
Identities = 91/249 (36%), Positives = 138/249 (55%), Gaps = 2/249 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+A VK+A VAIKI+ K D + + EIE +K L+H+++ + +ET
Sbjct: 22 FAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETA 79
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
+++++V+EY G L D I + E R F+Q+V AV Y H +G HRD+K ENLL
Sbjct: 80 NKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLL 139
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
D +KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 140 FDEYHKLKLIDFGLC---AKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMG 196
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 150
++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R+ +
Sbjct: 197 ILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISM 254
Query: 149 PQILADPWL 123
+L PW+
Sbjct: 255 KNLLNHPWI 263
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 163 bits (395), Expect = 1e-39
Identities = 91/249 (36%), Positives = 138/249 (55%), Gaps = 2/249 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+A VK+A VAIKI+ K D + + EIE +K L+H+++ + +ET
Sbjct: 22 FAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETA 79
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
+++++V+EY G L D I + E R F+Q+V AV Y H +G HRD+K ENLL
Sbjct: 80 NKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLL 139
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
D +KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 140 FDEYHKLKLIDFGLC---AKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMG 196
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 150
++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R+ +
Sbjct: 197 ILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISM 254
Query: 149 PQILADPWL 123
+L PW+
Sbjct: 255 KNLLNHPWI 263
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 163 bits (395), Expect = 1e-39
Identities = 91/249 (36%), Positives = 138/249 (55%), Gaps = 2/249 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+A VK+A VAIKI+ K D + + EIE +K L+H+++ + +ET
Sbjct: 22 FAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQHICQLYHVLETA 79
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
+++++V+EY G L D I + E R F+Q+V AV Y H +G HRD+K ENLL
Sbjct: 80 NKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLL 139
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
D +KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG
Sbjct: 140 FDEYHKLKLIDFGLC---AKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMG 196
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 150
++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R+ +
Sbjct: 197 ILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISM 254
Query: 149 PQILADPWL 123
+L PW+
Sbjct: 255 KNLLNHPWI 263
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 161 bits (390), Expect = 4e-39
Identities = 83/233 (35%), Positives = 138/233 (59%), Gaps = 1/233 (0%)
Frame = -3
Query: 821 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 642
+VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+ G
Sbjct: 59 KVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGE 117
Query: 641 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 462
L D + K + R++F+Q+V A+D+CH + HRD+K ENLL+D NI+++DFG
Sbjct: 118 LFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGM 177
Query: 461 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFD 282
A + +L ET CGS YA PE++KG Y + +D+WS GV+L+A++ G LPFD
Sbjct: 178 ASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFD 232
Query: 281 DTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPW 126
D N QLL++V+ V F + +C+ L+ ++ + R+ + QI PW
Sbjct: 233 DDNLRQLLEKVKRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 284
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 161 bits (390), Expect = 4e-39
Identities = 83/233 (35%), Positives = 138/233 (59%), Gaps = 1/233 (0%)
Frame = -3
Query: 821 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 642
+VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+ G
Sbjct: 59 KVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGE 117
Query: 641 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 462
L D + K + R++F+Q+V A+D+CH + HRD+K ENLL+D NI+++DFG
Sbjct: 118 LFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGM 177
Query: 461 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFD 282
A + +L ET CGS YA PE++KG Y + +D+WS GV+L+A++ G LPFD
Sbjct: 178 ASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFD 232
Query: 281 DTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPW 126
D N QLL++V+ V F + +C+ L+ ++ + R+ + QI PW
Sbjct: 233 DDNLRQLLEKVKRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 284
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 161 bits (390), Expect = 4e-39
Identities = 83/233 (35%), Positives = 138/233 (59%), Gaps = 1/233 (0%)
Frame = -3
Query: 821 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 642
+VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+ G
Sbjct: 59 KVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGE 117
Query: 641 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 462
L D + K + R++F+Q+V A+D+CH + HRD+K ENLL+D NI+++DFG
Sbjct: 118 LFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGM 177
Query: 461 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFD 282
A + +L ET CGS YA PE++KG Y + +D+WS GV+L+A++ G LPFD
Sbjct: 178 ASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFD 232
Query: 281 DTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPW 126
D N QLL++V+ V F + +C+ L+ ++ + R+ + QI PW
Sbjct: 233 DDNLRQLLEKVKRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 284
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 161 bits (390), Expect = 4e-39
Identities = 83/233 (35%), Positives = 138/233 (59%), Gaps = 1/233 (0%)
Frame = -3
Query: 821 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 642
+VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+ G
Sbjct: 75 KVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGE 133
Query: 641 LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGF 462
L D + K + R++F+Q+V A+D+CH + HRD+K ENLL+D NI+++DFG
Sbjct: 134 LFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGM 193
Query: 461 ARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFD 282
A + +L ET CGS YA PE++KG Y + +D+WS GV+L+A++ G LPFD
Sbjct: 194 ASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFD 248
Query: 281 DTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPW 126
D N QLL++V+ V F + +C+ L+ ++ + R+ + QI PW
Sbjct: 249 DDNLRQLLEKVKRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 300
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 159 bits (386), Expect = 1e-38
Identities = 94/247 (38%), Positives = 144/247 (58%), Gaps = 7/247 (2%)
Frame = -3
Query: 821 QVAIKIISKFQAPGD-YLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+VAIK+I K +A D Y+ K L RE ++ + ++H N+ + L +ET + Y+VME G
Sbjct: 87 KVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGG 146
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFG 465
+L+ I + + ++E+ RR+ +QL+ AV++ H GVVHRD+K ENLL+D NIKL DFG
Sbjct: 147 NLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFG 206
Query: 464 FARGHMKPKNGVFALSETF---CGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
+ G+ S+ F CGS AYA+PE+L Y P+ DVWS+GV +YA++ G
Sbjct: 207 LSN-----CAGILGYSDPFSTQCGSPAYAAPELLARKKYGPK-IDVWSIGVNMYAMLTGT 260
Query: 293 LPF--DDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPLKM-RVKIPQILADPWL 123
LPF + + L +++ +K P ++S + +L P + R I Q LA+ WL
Sbjct: 261 LPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWL 320
Query: 122 NPNQQSK 102
N N K
Sbjct: 321 NENYTGK 327
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 158 bits (384), Expect = 2e-38
Identities = 88/250 (35%), Positives = 142/250 (56%), Gaps = 3/250 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++ VKV + +VA+KI+++ + + + REI+ +K +H ++I+ Q I T
Sbjct: 28 TFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVIST 87
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+++VMEY G L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN+
Sbjct: 88 PSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENV 147
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +N K++DFG + +G F T CGS YA+PE++ G Y + D+WS
Sbjct: 148 LLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSS 202
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSF-PR--EPKVSAECRKLITRILAPLKMRV 156
GV+LYA++ G LPFDD + L K++ + + + P+ P V + + ++ + P+K R
Sbjct: 203 GVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQ--VDPMK-RA 259
Query: 155 KIPQILADPW 126
I I W
Sbjct: 260 SIKDIREHEW 269
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 158 bits (383), Expect = 3e-38
Identities = 90/256 (35%), Positives = 140/256 (54%), Gaps = 2/256 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++ VK+ +VA+KI+++ + + + REI+ +K +H ++I+ Q I T
Sbjct: 26 TFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVIST 85
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+
Sbjct: 86 PTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENV 145
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +N K++DFG + +G F T CGS YA+PE++ G Y + D+WS
Sbjct: 146 LLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSC 200
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVK 153
GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R
Sbjct: 201 GVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RAT 258
Query: 152 IPQILADPWLNPNQQS 105
I I W + S
Sbjct: 259 IKDIREHEWFKQDLPS 274
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 158 bits (383), Expect = 3e-38
Identities = 90/256 (35%), Positives = 140/256 (54%), Gaps = 2/256 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++ VK+ +VA+KI+++ + + + REI+ +K +H ++I+ Q I T
Sbjct: 26 TFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVIST 85
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+
Sbjct: 86 PTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENV 145
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +N K++DFG + +G F T CGS YA+PE++ G Y + D+WS
Sbjct: 146 LLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSC 200
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVK 153
GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R
Sbjct: 201 GVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RAT 258
Query: 152 IPQILADPWLNPNQQS 105
I I W + S
Sbjct: 259 IKDIREHEWFKQDLPS 274
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 158 bits (383), Expect = 3e-38
Identities = 90/256 (35%), Positives = 140/256 (54%), Gaps = 2/256 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++ VK+ +VA+KI+++ + + + REI+ +K +H ++I+ Q I T
Sbjct: 26 TFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVIST 85
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+
Sbjct: 86 PTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENV 145
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +N K++DFG + +G F T CGS YA+PE++ G Y + D+WS
Sbjct: 146 LLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSC 200
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVK 153
GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R
Sbjct: 201 GVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RAT 258
Query: 152 IPQILADPWLNPNQQS 105
I I W + S
Sbjct: 259 IKDIREHEWFKQDLPS 274
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 158 bits (383), Expect = 3e-38
Identities = 79/206 (38%), Positives = 123/206 (59%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++ VKV + +VA+KI+++ + + + REI+ +K +H ++I+ Q I T
Sbjct: 28 TFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVIST 87
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+++VMEY G L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN+
Sbjct: 88 PSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENV 147
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +N K++DFG + +G F T CGS YA+PE++ G Y + D+WS
Sbjct: 148 LLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSS 202
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV 249
GV+LYA++ G LPFDD + L K++
Sbjct: 203 GVILYALLCGTLPFDDDHVPTLFKKI 228
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 158 bits (383), Expect = 3e-38
Identities = 90/256 (35%), Positives = 140/256 (54%), Gaps = 2/256 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++ VK+ +VA+KI+++ + + + REI+ +K +H ++I+ Q I T
Sbjct: 26 TFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVIST 85
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+
Sbjct: 86 PTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENV 145
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +N K++DFG + +G F T CGS YA+PE++ G Y + D+WS
Sbjct: 146 LLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSC 200
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVK 153
GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R
Sbjct: 201 GVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RAT 258
Query: 152 IPQILADPWLNPNQQS 105
I I W + S
Sbjct: 259 IKDIREHEWFKQDLPS 274
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 157 bits (382), Expect = 4e-38
Identities = 96/282 (34%), Positives = 160/282 (56%), Gaps = 8/282 (2%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+A VK+A +VA+K+I K + L +E+ +K ++H N++R + I+T
Sbjct: 28 FAVVKLARHVFTGEKVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQ 86
Query: 683 HRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN+
Sbjct: 87 TKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENV 146
Query: 506 LM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 333
+ GL +KL+DFGF+ K T CGS AY++PEIL G Y D+W
Sbjct: 147 VFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIW 200
Query: 332 SMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKVSAECRKLITRIL-APLKMR 159
S+GV+L+ +V G+ PF + N ++ L + + K + P VS EC+ LITR+L K R
Sbjct: 201 SLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH--VSKECKDLITRMLQRDPKRR 258
Query: 158 VKIPQILADPWL---NPNQQSKHDETDLQEHAKTSKEEIKSV 42
+ +I PWL +P+ +K++ L + S+EE S+
Sbjct: 259 ASLEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSEEEHNSI 299
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 157 bits (380), Expect = 6e-38
Identities = 96/282 (34%), Positives = 160/282 (56%), Gaps = 8/282 (2%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+A VK+A +VA+K+I K + L +E+ +K ++H N++R + I+T
Sbjct: 27 FAVVKLARHVFTGEKVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQ 85
Query: 683 HRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN+
Sbjct: 86 TKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENV 145
Query: 506 LM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 333
+ GL +KL+DFGF+ K T CGS AY++PEIL G Y D+W
Sbjct: 146 VFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIW 199
Query: 332 SMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKVSAECRKLITRIL-APLKMR 159
S+GV+L+ +V G+ PF + N ++ L + + K + P VS EC+ LITR+L K R
Sbjct: 200 SLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH--VSKECKDLITRMLQRDPKRR 257
Query: 158 VKIPQILADPWL---NPNQQSKHDETDLQEHAKTSKEEIKSV 42
+ +I PWL +P+ +K++ L + S+EE S+
Sbjct: 258 AYLEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSEEEHNSI 298
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 157 bits (380), Expect = 6e-38
Identities = 96/282 (34%), Positives = 160/282 (56%), Gaps = 8/282 (2%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+A VK+A +VA+K+I K + L +E+ +K ++H N++R + I+T
Sbjct: 27 FAVVKLARHVFTGEKVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQ 85
Query: 683 HRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN+
Sbjct: 86 TKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKLHVVHRDLKPENV 145
Query: 506 LM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 333
+ GL +KL+DFGF+ K T CGS AY++PEIL G Y D+W
Sbjct: 146 VFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIW 199
Query: 332 SMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKVSAECRKLITRIL-APLKMR 159
S+GV+L+ +V G+ PF + N ++ L + + K + P VS EC+ LITR+L K R
Sbjct: 200 SLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH--VSKECKDLITRMLQRDPKRR 257
Query: 158 VKIPQILADPWL---NPNQQSKHDETDLQEHAKTSKEEIKSV 42
+ +I PWL +P+ +K++ L + S+EE S+
Sbjct: 258 ASLEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSEEEHNSI 298
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 156 bits (379), Expect = 9e-38
Identities = 79/213 (37%), Positives = 129/213 (60%), Gaps = 1/213 (0%)
Frame = -3
Query: 824 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 648
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 647 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 468
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 467 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 288
G A + +L ET CGS YA PE+++G Y + +DVWS GV+L+A++ G LP
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALP 215
Query: 287 FDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 189
FDD N QLL++V+ V F + +C+ L+
Sbjct: 216 FDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 156 bits (379), Expect = 9e-38
Identities = 79/213 (37%), Positives = 129/213 (60%), Gaps = 1/213 (0%)
Frame = -3
Query: 824 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 648
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 647 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 468
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 467 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 288
G A + +L ET CGS YA PE+++G Y + +DVWS GV+L+A++ G LP
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALP 215
Query: 287 FDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 189
FDD N QLL++V+ V F + +C+ L+
Sbjct: 216 FDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 156 bits (379), Expect = 9e-38
Identities = 79/213 (37%), Positives = 129/213 (60%), Gaps = 1/213 (0%)
Frame = -3
Query: 824 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 648
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 88 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 146
Query: 647 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 468
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 147 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 206
Query: 467 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 288
G A + +L ET CGS YA PE+++G Y + +DVWS GV+L+A++ G LP
Sbjct: 207 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALP 261
Query: 287 FDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 189
FDD N QLL++V+ V F + +C+ L+
Sbjct: 262 FDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 293
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 156 bits (379), Expect = 9e-38
Identities = 79/213 (37%), Positives = 129/213 (60%), Gaps = 1/213 (0%)
Frame = -3
Query: 824 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 648
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 647 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 468
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 467 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 288
G A + +L ET CGS YA PE+++G Y + +DVWS GV+L+A++ G LP
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALP 215
Query: 287 FDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 189
FDD N QLL++V+ V F + +C+ L+
Sbjct: 216 FDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 156 bits (379), Expect = 9e-38
Identities = 79/213 (37%), Positives = 129/213 (60%), Gaps = 1/213 (0%)
Frame = -3
Query: 824 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 648
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 647 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 468
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 467 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 288
G A + +L ET CGS YA PE+++G Y + +DVWS GV+L+A++ G LP
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALP 215
Query: 287 FDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 189
FDD N QLL++V+ V F + +C+ L+
Sbjct: 216 FDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 156 bits (379), Expect = 9e-38
Identities = 79/213 (37%), Positives = 129/213 (60%), Gaps = 1/213 (0%)
Frame = -3
Query: 824 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 648
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 647 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 468
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 467 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 288
G A + +L ET CGS YA PE+++G Y + +DVWS GV+L+A++ G LP
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALP 215
Query: 287 FDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 189
FDD N QLL++V+ V F + +C+ L+
Sbjct: 216 FDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 156 bits (379), Expect = 9e-38
Identities = 79/213 (37%), Positives = 129/213 (60%), Gaps = 1/213 (0%)
Frame = -3
Query: 824 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 648
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 647 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 468
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 467 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 288
G A + +L ET CGS YA PE+++G Y + +DVWS GV+L+A++ G LP
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALP 215
Query: 287 FDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 189
FDD N QLL++V+ V F + +C+ L+
Sbjct: 216 FDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 156 bits (379), Expect = 9e-38
Identities = 79/213 (37%), Positives = 129/213 (60%), Gaps = 1/213 (0%)
Frame = -3
Query: 824 CQ-VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAEN 648
CQ VAIKI+++ + L K + REI ++K ++H ++++ E +Y+V+E+
Sbjct: 42 CQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSG 100
Query: 647 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 468
G L D + K + R++F+Q++ A+D+CH + HRD+K ENLL+D NI+++DF
Sbjct: 101 GELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADF 160
Query: 467 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 288
G A + +L ET CGS YA PE+++G Y + +DVWS GV+L+A++ G LP
Sbjct: 161 GMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALP 215
Query: 287 FDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 189
FDD N QLL++V+ V F + +C+ L+
Sbjct: 216 FDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 156 bits (378), Expect = 1e-37
Identities = 88/249 (35%), Positives = 137/249 (55%), Gaps = 2/249 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++ VK+ +VA+KI+++ + + + REI+ +K +H ++I+ Q I T
Sbjct: 26 TFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVIST 85
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+
Sbjct: 86 PTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENV 145
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +N K++DFG + +G F T CGS Y +PE++ G Y + D+WS
Sbjct: 146 LLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYTAPEVISGRLYAGPEVDIWSC 200
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVK 153
GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R
Sbjct: 201 GVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RAT 258
Query: 152 IPQILADPW 126
I I W
Sbjct: 259 IKDIREHEW 267
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 156 bits (378), Expect = 1e-37
Identities = 89/256 (34%), Positives = 139/256 (54%), Gaps = 2/256 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++ V + +VA+KI+++ + + + REI+ +K +H ++I+ Q I T
Sbjct: 26 TFGKVNIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVIST 85
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+
Sbjct: 86 PTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENV 145
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +N K++DFG + +G F T CGS YA+PE++ G Y + D+WS
Sbjct: 146 LLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSC 200
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVK 153
GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R
Sbjct: 201 GVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RAT 258
Query: 152 IPQILADPWLNPNQQS 105
I I W + S
Sbjct: 259 IKDIREHEWFKQDLPS 274
>AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leucine
zipper kinase v2 protein.
Length = 619
Score = 156 bits (378), Expect = 1e-37
Identities = 83/218 (38%), Positives = 125/218 (57%), Gaps = 5/218 (2%)
Frame = -3
Query: 761 LPR---EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 591
LPR EIE +K L+H+++ + +ET +++++V+EY G L D I + E R
Sbjct: 19 LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETR 78
Query: 590 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSET 411
F+Q+V AV Y H +G HRD+K ENLL D +KL DFG KPK +T
Sbjct: 79 VVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC---AKPKGNKDYHLQT 135
Query: 410 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVS 234
CGS AYA+PE+++G Y ++DVWSMG++LY ++ G LPFDD N L K++ + K
Sbjct: 136 CCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYD 195
Query: 233 FPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
P+ +S L+ ++L K R+ + +L PW+
Sbjct: 196 VPK--WLSPSSILLLQQMLQVDPKKRISMKNLLNHPWI 231
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 153 bits (372), Expect = 6e-37
Identities = 76/211 (36%), Positives = 125/211 (59%), Gaps = 1/211 (0%)
Frame = -3
Query: 755 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 576
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 17 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 76
Query: 575 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 396
+V A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 77 IVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 131
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 216
YA PE++KG Y + +D+WS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 132 HYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 190
Query: 215 VSAECRKLITRIL-APLKMRVKIPQILADPW 126
+ +C+ L+ ++ + R+ + QI PW
Sbjct: 191 IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 221
>AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens
cDNA FLJ14587 fis, clone NT2RM4001758, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK
(EC 2.7.1.-). ).
Length = 638
Score = 147 bits (355), Expect = 7e-35
Identities = 79/202 (39%), Positives = 120/202 (59%), Gaps = 3/202 (1%)
Frame = -3
Query: 665 MEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLN 486
MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +N
Sbjct: 1 MEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMN 60
Query: 485 IKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAI 306
IK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+LY +
Sbjct: 61 IKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTL 115
Query: 305 VYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQILA 135
V G LPFD N +L ++V + K P +S +C L+ ++L P+K R + QI+
Sbjct: 116 VSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RGSLEQIMK 172
Query: 134 DPWLNPNQQSKHDETDLQEHAK 69
D W+N H+E +L+ + +
Sbjct: 173 DRWMNVG----HEEEELKPYTE 190
>AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 758
Score = 145 bits (352), Expect = 2e-34
Identities = 94/269 (34%), Positives = 145/269 (53%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+
Sbjct: 70 NFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPNI--------- 119
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 120 -------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENL 166
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 167 LLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 221
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L P+K R
Sbjct: 222 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RG 278
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H+E +L+ + +
Sbjct: 279 SLEQIMKDRWMNVG----HEEEELKPYTE 303
>AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein.
Length = 870
Score = 145 bits (352), Expect = 2e-34
Identities = 94/269 (34%), Positives = 145/269 (53%), Gaps = 3/269 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK+A +VA+KII K Q L+K RE+ ++K L H N+
Sbjct: 182 NFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPNI--------- 231
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
G + D + + E R F+Q+V AV YCH++ +VHRD+K ENL
Sbjct: 232 -------------GEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENL 278
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+
Sbjct: 279 LLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSL 333
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 156
GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L P+K R
Sbjct: 334 GVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RG 390
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHAK 69
+ QI+ D W+N H+E +L+ + +
Sbjct: 391 SLEQIMKDRWMNVG----HEEEELKPYTE 415
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 144 bits (350), Expect = 3e-34
Identities = 81/255 (31%), Positives = 144/255 (56%), Gaps = 3/255 (1%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + VA+K++ K Q + L+ L REIE+ L+H N++R
Sbjct: 20 FGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDA 79
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G L ++K + +DE R +++ +A+ YCH++ V+HRDIK ENLL
Sbjct: 80 RRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTYCHDKKVIHRDIKPENLL 139
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ P+ +T CG+ Y PE+++G Y + D+W +G
Sbjct: 140 LGFRGEVKIADFGWSVHTPLPER------KTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG 192
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVK 153
V+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+
Sbjct: 193 VLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLP 249
Query: 152 IPQILADPWLNPNQQ 108
+ QIL PW+ + +
Sbjct: 250 LAQILKHPWVQAHSR 264
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 143 bits (347), Expect = 6e-34
Identities = 79/221 (35%), Positives = 124/221 (56%), Gaps = 15/221 (6%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++ VKV + +VA+KI+++ + + + REI+ +K +H ++I+ Q I T
Sbjct: 37 TFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVIST 96
Query: 686 THRVYIVMEYAENGSLLDIIRKD---------------QHIDETRGRRWFKQLVEAVDYC 552
+++VMEY G L D I K+ + +DE RR F+Q++ VDYC
Sbjct: 97 PSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELDEKESRRLFQQILSGVDYC 156
Query: 551 HERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 372
H VVHRD+K EN+L+D +N K++DFG + +G F T CGS YA+PE++
Sbjct: 157 HRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVI 211
Query: 371 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV 249
G Y + D+WS GV+LYA++ G LPFDD + L K++
Sbjct: 212 SGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKI 252
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 143 bits (346), Expect = 9e-34
Identities = 82/255 (32%), Positives = 143/255 (56%), Gaps = 3/255 (1%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + VA+K++ K Q + L+ L REIE+ L+H N++R
Sbjct: 20 FGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDA 79
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G L ++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL
Sbjct: 80 RRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLL 139
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ H +T CG+ Y PE+++G Y + D+W +G
Sbjct: 140 LGFRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG 192
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVK 153
V+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+
Sbjct: 193 VLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLP 249
Query: 152 IPQILADPWLNPNQQ 108
+ QIL PW+ + +
Sbjct: 250 LAQILKHPWVQAHSR 264
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 143 bits (346), Expect = 9e-34
Identities = 82/255 (32%), Positives = 143/255 (56%), Gaps = 3/255 (1%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + VA+K++ K Q + L+ L REIE+ L+H N++R
Sbjct: 51 FGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDA 110
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G L ++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL
Sbjct: 111 RRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLL 170
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ H +T CG+ Y PE+++G Y + D+W +G
Sbjct: 171 LGFRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG 223
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVK 153
V+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+
Sbjct: 224 VLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLP 280
Query: 152 IPQILADPWLNPNQQ 108
+ QIL PW+ + +
Sbjct: 281 LAQILKHPWVQAHSR 295
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 143 bits (346), Expect = 9e-34
Identities = 82/255 (32%), Positives = 143/255 (56%), Gaps = 3/255 (1%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + VA+K++ K Q + L+ L REIE+ L+H N++R
Sbjct: 35 FGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDA 94
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G L ++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL
Sbjct: 95 RRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLL 154
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ H +T CG+ Y PE+++G Y + D+W +G
Sbjct: 155 LGFRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG 207
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVK 153
V+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+
Sbjct: 208 VLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLP 264
Query: 152 IPQILADPWLNPNQQ 108
+ QIL PW+ + +
Sbjct: 265 LAQILKHPWVQAHSR 279
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 143 bits (346), Expect = 9e-34
Identities = 82/255 (32%), Positives = 143/255 (56%), Gaps = 3/255 (1%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + VA+K++ K Q + L+ L REIE+ L+H N++R
Sbjct: 54 FGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNHFHDA 113
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G L ++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL
Sbjct: 114 RRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLL 173
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ H +T CG+ Y PE+++G Y + D+W +G
Sbjct: 174 LGFRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG 226
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVK 153
V+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+
Sbjct: 227 VLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLP 283
Query: 152 IPQILADPWLNPNQQ 108
+ QIL PW+ + +
Sbjct: 284 LAQILKHPWVQAHSR 298
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 143 bits (346), Expect = 9e-34
Identities = 82/255 (32%), Positives = 143/255 (56%), Gaps = 3/255 (1%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + VA+K++ K Q + L+ L REIE+ L+H N++R
Sbjct: 54 FGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPNILRLYNYFHDA 113
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G L ++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL
Sbjct: 114 RRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLL 173
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ H +T CG+ Y PE+++G Y + D+W +G
Sbjct: 174 LGFRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIG 226
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVK 153
V+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+
Sbjct: 227 VLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLP 283
Query: 152 IPQILADPWLNPNQQ 108
+ QIL PW+ + +
Sbjct: 284 LAQILKHPWVQAHSR 298
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 142 bits (344), Expect = 1e-33
Identities = 83/250 (33%), Positives = 132/250 (52%), Gaps = 2/250 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ VK+ +VAIKI+ K + ++ L REI ++ L H N+IR + +ET
Sbjct: 84 NFSQVKLGIHSLTKEKVAIKILDKTKLD-QKTQRLLSREISSMEKLHHPNIIRLYEVVET 142
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++++VMEYA G L I + + E + F Q+V AV + HE ++HRD+K EN+
Sbjct: 143 LSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENV 202
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
+K+ DFGF+ K + + TFCGS YA+PE+ + Y D+W++
Sbjct: 203 FYTSNTCVKVGDFGFSTVSKKGE-----MLNTFCGSPPYAAPELFRDEHYIGIYVDIWAL 257
Query: 326 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILAPLKM-RVK 153
GV+LY +V G +PF +L K + + S P P VS C +LI +L + R
Sbjct: 258 GVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVP--PHVSEPCHRLIRGVLQQIPTERYG 315
Query: 152 IPQILADPWL 123
I I+ D W+
Sbjct: 316 IDCIMNDEWM 325
>AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens
cDNA FLJ90097 fis, clone HEMBA1005929, weakly similar to
H.sapiens mRNA for serine/threonine protein kinase EMK.
).
Length = 426
Score = 142 bits (344), Expect = 1e-33
Identities = 74/185 (40%), Positives = 111/185 (60%), Gaps = 3/185 (1%)
Frame = -3
Query: 665 MEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLN 486
MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D N
Sbjct: 1 MEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEAN 60
Query: 485 IKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAI 306
IK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+LY +
Sbjct: 61 IKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTL 115
Query: 305 VYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIPQILA 135
V G LPFD N +L ++V + K P +S +C ++ R +L P K R + QI+
Sbjct: 116 VSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLEQIMK 172
Query: 134 DPWLN 120
D W+N
Sbjct: 173 DKWIN 177
>AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 603
Score = 141 bits (341), Expect = 3e-33
Identities = 66/181 (36%), Positives = 109/181 (60%)
Frame = -3
Query: 731 LKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 552
++H ++++ E +Y+V+E+ G L D + K + R++F+Q++ A+D+C
Sbjct: 2 IEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFC 61
Query: 551 HERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 372
H + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE++
Sbjct: 62 HSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVI 116
Query: 371 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKL 192
+G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L
Sbjct: 117 RGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSL 175
Query: 191 I 189
+
Sbjct: 176 L 176
>AF542390-1|AAN62841.1| 258|Homo sapiens AT03158-like protein
protein.
Length = 258
Score = 139 bits (337), Expect = 1e-32
Identities = 71/149 (47%), Positives = 95/149 (63%), Gaps = 13/149 (8%)
Frame = -3
Query: 530 RDIKCENLLMDHGLNIKLSDFGFARGHMKPKN------------GVFA-LSETFCGSYAY 390
RD+K ENLL+D N+K+SDFGFA+ M P N F+ LS+T+CGS+AY
Sbjct: 77 RDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAY 134
Query: 389 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 210
A PEIL+G+PY P SD WSMGV+LY +V LPFDDTN +LL++ Q +V+FP +S
Sbjct: 135 ACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTIS 194
Query: 209 AECRKLITRILAPLKMRVKIPQILADPWL 123
EC+ LI ++L R I I+ D W+
Sbjct: 195 QECKNLILQMLRQATKRATILDIIKDSWV 223
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 139 bits (336), Expect = 1e-32
Identities = 90/298 (30%), Positives = 154/298 (51%), Gaps = 13/298 (4%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S+ V A+ + AIK ++K +A G K L RE+ ++K +KHE++I Q ET
Sbjct: 126 SFGIVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSVKHEHIIHLEQVFET 184
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y+VME E+G L +I+ + H E R + L A+ Y H +VHRD+K EN+
Sbjct: 185 PKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENI 244
Query: 506 LM---------DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 354
++ + LNIK++DFG A +K ++ A+ + CG+ Y +PE++ Y
Sbjct: 245 MVKSSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQATCGTPIYMAPEVISAHDY- 300
Query: 353 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVS-AECRKLITRI 180
Q D+WS+GVV+Y ++ G PF ++ +L + + + ++ F S ++C K + +
Sbjct: 301 SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQ 360
Query: 179 LAPL--KMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTSKEEIKSVNIGTVTYDRK 12
L + R+ ++L + WL N+ S T++ E K K +SV T K
Sbjct: 361 LMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNK 418
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens cDNA
FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 139 bits (336), Expect = 1e-32
Identities = 90/298 (30%), Positives = 154/298 (51%), Gaps = 13/298 (4%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S+ V A+ + AIK ++K +A G K L RE+ ++K +KHE++I Q ET
Sbjct: 126 SFGIVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSVKHEHIIHLEQVFET 184
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y+VME E+G L +I+ + H E R + L A+ Y H +VHRD+K EN+
Sbjct: 185 PKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENI 244
Query: 506 LM---------DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 354
++ + LNIK++DFG A +K ++ A+ + CG+ Y +PE++ Y
Sbjct: 245 MVKSSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQATCGTPIYMAPEVISAHDY- 300
Query: 353 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVS-AECRKLITRI 180
Q D+WS+GVV+Y ++ G PF ++ +L + + + ++ F S ++C K + +
Sbjct: 301 SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQ 360
Query: 179 LAPL--KMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTSKEEIKSVNIGTVTYDRK 12
L + R+ ++L + WL N+ S T++ E K K +SV T K
Sbjct: 361 LMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNK 418
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 139 bits (336), Expect = 1e-32
Identities = 90/298 (30%), Positives = 154/298 (51%), Gaps = 13/298 (4%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S+ V A+ + AIK ++K +A G K L RE+ ++K +KHE++I Q ET
Sbjct: 126 SFGIVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSVKHEHIIHLEQVFET 184
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y+VME E+G L +I+ + H E R + L A+ Y H +VHRD+K EN+
Sbjct: 185 PKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENI 244
Query: 506 LM---------DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 354
++ + LNIK++DFG A +K ++ A+ + CG+ Y +PE++ Y
Sbjct: 245 MVKSSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQATCGTPIYMAPEVISAHDY- 300
Query: 353 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVS-AECRKLITRI 180
Q D+WS+GVV+Y ++ G PF ++ +L + + + ++ F S ++C K + +
Sbjct: 301 SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQ 360
Query: 179 LAPL--KMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTSKEEIKSVNIGTVTYDRK 12
L + R+ ++L + WL N+ S T++ E K K +SV T K
Sbjct: 361 LMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNK 418
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 136 bits (329), Expect = 1e-31
Identities = 77/268 (28%), Positives = 138/268 (51%), Gaps = 1/268 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + +A+K++ K Q ++ L RE+E+ L+H N++R
Sbjct: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL
Sbjct: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL 263
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + + T CG+ Y PE+++G + D+WS+G
Sbjct: 264 LGSAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG 316
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R +
Sbjct: 317 VLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
Query: 146 QILADPWLNPNQQSKHDETDLQEHAKTS 63
++L PW+ N + + + +K S
Sbjct: 376 EVLEHPWITANSSKPSNCQNKESASKQS 403
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 136 bits (329), Expect = 1e-31
Identities = 77/268 (28%), Positives = 138/268 (51%), Gaps = 1/268 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + +A+K++ K Q ++ L RE+E+ L+H N++R
Sbjct: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL
Sbjct: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL 263
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + + T CG+ Y PE+++G + D+WS+G
Sbjct: 264 LGSAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG 316
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R +
Sbjct: 317 VLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
Query: 146 QILADPWLNPNQQSKHDETDLQEHAKTS 63
++L PW+ N + + + +K S
Sbjct: 376 EVLEHPWITANSSKPSNCQNKESASKQS 403
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 136 bits (329), Expect = 1e-31
Identities = 77/268 (28%), Positives = 138/268 (51%), Gaps = 1/268 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + +A+K++ K Q ++ L RE+E+ L+H N++R
Sbjct: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL
Sbjct: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL 263
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + + T CG+ Y PE+++G + D+WS+G
Sbjct: 264 LGSAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG 316
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R +
Sbjct: 317 VLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
Query: 146 QILADPWLNPNQQSKHDETDLQEHAKTS 63
++L PW+ N + + + +K S
Sbjct: 376 EVLEHPWITANSSKPSNCQNKESASKQS 403
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 136 bits (329), Expect = 1e-31
Identities = 77/268 (28%), Positives = 138/268 (51%), Gaps = 1/268 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + +A+K++ K Q ++ L RE+E+ L+H N++R
Sbjct: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL
Sbjct: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL 263
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + + T CG+ Y PE+++G + D+WS+G
Sbjct: 264 LGSAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG 316
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R +
Sbjct: 317 VLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
Query: 146 QILADPWLNPNQQSKHDETDLQEHAKTS 63
++L PW+ N + + + +K S
Sbjct: 376 EVLEHPWITANSSKPSNCQNKESASKQS 403
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 136 bits (329), Expect = 1e-31
Identities = 77/268 (28%), Positives = 138/268 (51%), Gaps = 1/268 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + +A+K++ K Q ++ L RE+E+ L+H N++R
Sbjct: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL
Sbjct: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL 263
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + + T CG+ Y PE+++G + D+WS+G
Sbjct: 264 LGSAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG 316
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R +
Sbjct: 317 VLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
Query: 146 QILADPWLNPNQQSKHDETDLQEHAKTS 63
++L PW+ N + + + +K S
Sbjct: 376 EVLEHPWITANSSKPSNCQNKESASKQS 403
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 136 bits (329), Expect = 1e-31
Identities = 77/268 (28%), Positives = 138/268 (51%), Gaps = 1/268 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + +A+K++ K Q ++ L RE+E+ L+H N++R
Sbjct: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL
Sbjct: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL 263
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + + T CG+ Y PE+++G + D+WS+G
Sbjct: 264 LGSAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG 316
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R +
Sbjct: 317 VLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
Query: 146 QILADPWLNPNQQSKHDETDLQEHAKTS 63
++L PW+ N + + + +K S
Sbjct: 376 EVLEHPWITANSSKPSNCQNKESASKQS 403
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 136 bits (329), Expect = 1e-31
Identities = 77/268 (28%), Positives = 138/268 (51%), Gaps = 1/268 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + +A+K++ K Q ++ L RE+E+ L+H N++R
Sbjct: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL
Sbjct: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL 263
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + + T CG+ Y PE+++G + D+WS+G
Sbjct: 264 LGSAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG 316
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R +
Sbjct: 317 VLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
Query: 146 QILADPWLNPNQQSKHDETDLQEHAKTS 63
++L PW+ N + + + +K S
Sbjct: 376 EVLEHPWITANSSKPSNCQNKESASKQS 403
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 136 bits (329), Expect = 1e-31
Identities = 77/268 (28%), Positives = 138/268 (51%), Gaps = 1/268 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + +A+K++ K Q ++ L RE+E+ L+H N++R
Sbjct: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL
Sbjct: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL 263
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + + T CG+ Y PE+++G + D+WS+G
Sbjct: 264 LGSAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG 316
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R +
Sbjct: 317 VLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLR 375
Query: 146 QILADPWLNPNQQSKHDETDLQEHAKTS 63
++L PW+ N + + + +K S
Sbjct: 376 EVLEHPWITANSSKPSNCQNKESASKQS 403
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 136 bits (328), Expect = 1e-31
Identities = 77/227 (33%), Positives = 131/227 (57%), Gaps = 4/227 (1%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+A VK+A +VA+K+I K + L +E+ +K ++H N++R + I+T
Sbjct: 27 FAVVKLARHVFTGEKVAVKVIDKTKLD-TLATGHLFQEVRCMKLVQHPNIVRLYEVIDTQ 85
Query: 683 HRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN+
Sbjct: 86 TKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENV 145
Query: 506 LM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 333
+ GL +KL+DFGF+ K T CGS AY++PEIL G Y D+W
Sbjct: 146 VFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIW 199
Query: 332 SMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKVSAECRK 195
S+GV+L+ +V + PF + N ++ L + + K + P VS EC++
Sbjct: 200 SLGVILFMLVCEQPPFQEANDSETLTMIMDCKYTVPSH--VSKECKE 244
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 135 bits (327), Expect = 2e-31
Identities = 76/268 (28%), Positives = 138/268 (51%), Gaps = 1/268 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + +A+K++ K Q ++ L RE+E+ L+H N++R
Sbjct: 143 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 202
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G++ ++K DE R + ++ A+ YCH + V+HRDIK ENLL
Sbjct: 203 TRVYLILEYAPLGTVYRELQKLSKFDEQRTANLYNRIANALSYCHSKRVIHRDIKPENLL 262
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + + T CG+ Y PE+++G + D+WS+G
Sbjct: 263 LGSAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG 315
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R +
Sbjct: 316 VLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLR 374
Query: 146 QILADPWLNPNQQSKHDETDLQEHAKTS 63
++L PW+ N + + + +K S
Sbjct: 375 EVLEHPWITANSSKPSNCQNKESASKQS 402
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 131 bits (316), Expect = 4e-30
Identities = 83/238 (34%), Positives = 126/238 (52%), Gaps = 7/238 (2%)
Frame = -3
Query: 815 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 636
AIK+I G ++ E+ V++ ++H N+I+ ++ ET RVY+VME A G L
Sbjct: 125 AIKMIETKYREG---REVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELF 181
Query: 635 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH-GLNIK--LSDFG 465
D I E R + +++ V Y H G+ HRD+K ENLL H G + K ++DFG
Sbjct: 182 DRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFG 241
Query: 464 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPF 285
A K G L +T CG+ Y +PE+L PY D+W++GV+ Y ++ G +PF
Sbjct: 242 LASAR---KKGDDCLMKTTCGTPEYIAPEVLVRKPY-TNSVDMWALGVIAYILLSGTMPF 297
Query: 284 DDTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
+D N T+L +Q+ + K S+ E P VS + I R+L R+ Q L PW+
Sbjct: 298 EDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 131 bits (316), Expect = 4e-30
Identities = 83/238 (34%), Positives = 126/238 (52%), Gaps = 7/238 (2%)
Frame = -3
Query: 815 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 636
AIK+I G ++ E+ V++ ++H N+I+ ++ ET RVY+VME A G L
Sbjct: 125 AIKMIETKYREG---REVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELF 181
Query: 635 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH-GLNIK--LSDFG 465
D I E R + +++ V Y H G+ HRD+K ENLL H G + K ++DFG
Sbjct: 182 DRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFG 241
Query: 464 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPF 285
A K G L +T CG+ Y +PE+L PY D+W++GV+ Y ++ G +PF
Sbjct: 242 LASAR---KKGDDCLMKTTCGTPEYIAPEVLVRKPY-TNSVDMWALGVIAYILLSGTMPF 297
Query: 284 DDTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
+D N T+L +Q+ + K S+ E P VS + I R+L R+ Q L PW+
Sbjct: 298 EDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 130 bits (314), Expect = 6e-30
Identities = 76/265 (28%), Positives = 137/265 (51%), Gaps = 1/265 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + + VA+K++ K Q + ++ L REIE+ L H N++R
Sbjct: 88 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDR 147
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
R+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL
Sbjct: 148 RRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLL 207
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + +T CG+ Y PE+++G + + D+W +G
Sbjct: 208 LGLKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG 260
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+ +
Sbjct: 261 VLCYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLA 319
Query: 146 QILADPWLNPNQQSKHDETDLQEHA 72
Q+ A PW+ N + + LQ A
Sbjct: 320 QVSAHPWVRANSRRVLPPSALQSVA 344
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 130 bits (314), Expect = 6e-30
Identities = 76/265 (28%), Positives = 137/265 (51%), Gaps = 1/265 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + + VA+K++ K Q + ++ L REIE+ L H N++R
Sbjct: 88 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDR 147
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
R+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL
Sbjct: 148 RRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLL 207
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + +T CG+ Y PE+++G + + D+W +G
Sbjct: 208 LGLKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG 260
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+ +
Sbjct: 261 VLCYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLA 319
Query: 146 QILADPWLNPNQQSKHDETDLQEHA 72
Q+ A PW+ N + + LQ A
Sbjct: 320 QVSAHPWVRANSRRVLPPSALQSVA 344
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 130 bits (314), Expect = 6e-30
Identities = 76/265 (28%), Positives = 137/265 (51%), Gaps = 1/265 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + + VA+K++ K Q + ++ L REIE+ L H N++R
Sbjct: 88 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDR 147
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
R+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL
Sbjct: 148 RRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLL 207
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + +T CG+ Y PE+++G + + D+W +G
Sbjct: 208 LGLKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG 260
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+ +
Sbjct: 261 VLCYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLA 319
Query: 146 QILADPWLNPNQQSKHDETDLQEHA 72
Q+ A PW+ N + + LQ A
Sbjct: 320 QVSAHPWVRANSRRVLPPSALQSVA 344
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 130 bits (314), Expect = 6e-30
Identities = 76/265 (28%), Positives = 137/265 (51%), Gaps = 1/265 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + + VA+K++ K Q + ++ L REIE+ L H N++R
Sbjct: 88 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDR 147
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
R+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL
Sbjct: 148 RRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLL 207
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + +T CG+ Y PE+++G + + D+W +G
Sbjct: 208 LGLKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG 260
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+ +
Sbjct: 261 VLCYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLA 319
Query: 146 QILADPWLNPNQQSKHDETDLQEHA 72
Q+ A PW+ N + + LQ A
Sbjct: 320 QVSAHPWVRANSRRVLPPSALQSVA 344
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 130 bits (314), Expect = 6e-30
Identities = 76/265 (28%), Positives = 137/265 (51%), Gaps = 1/265 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + + VA+K++ K Q + ++ L REIE+ L H N++R
Sbjct: 88 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDR 147
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
R+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL
Sbjct: 148 RRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLL 207
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + +T CG+ Y PE+++G + + D+W +G
Sbjct: 208 LGLKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG 260
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+ +
Sbjct: 261 VLCYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLA 319
Query: 146 QILADPWLNPNQQSKHDETDLQEHA 72
Q+ A PW+ N + + LQ A
Sbjct: 320 QVSAHPWVRANSRRVLPPSALQSVA 344
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 130 bits (313), Expect = 8e-30
Identities = 76/265 (28%), Positives = 137/265 (51%), Gaps = 1/265 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + + VA+K++ K Q + ++ L REIE+ L H N++R
Sbjct: 115 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDR 174
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
R+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL
Sbjct: 175 RRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLL 234
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + +T CG+ Y PE+++G + + D+W +G
Sbjct: 235 LGLKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG 287
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+ +
Sbjct: 288 VLCYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPMGAQDLISKLLRHNPSERLPLA 346
Query: 146 QILADPWLNPNQQSKHDETDLQEHA 72
Q+ A PW+ N + + LQ A
Sbjct: 347 QVSAHPWVRANSRRVLPPSALQSVA 371
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 130 bits (313), Expect = 8e-30
Identities = 76/265 (28%), Positives = 137/265 (51%), Gaps = 1/265 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + + VA+K++ K Q + ++ L REIE+ L H N++R
Sbjct: 88 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDR 147
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
R+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL
Sbjct: 148 RRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLL 207
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + +T CG+ Y PE+++G + + D+W +G
Sbjct: 208 LGLKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIG 260
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+ +
Sbjct: 261 VLCYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPMGAQDLISKLLRHNPSERLPLA 319
Query: 146 QILADPWLNPNQQSKHDETDLQEHA 72
Q+ A PW+ N + + LQ A
Sbjct: 320 QVSAHPWVRANSRRVLPPSALQSVA 344
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 128 bits (310), Expect = 2e-29
Identities = 84/252 (33%), Positives = 129/252 (51%), Gaps = 3/252 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y V++A + VA+KI+ +A + + +EI + K L HEN+++F
Sbjct: 19 AYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRRE 76
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENL
Sbjct: 77 GNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENL 136
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS
Sbjct: 137 LLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSC 194
Query: 326 GVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRV 156
G+VL A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+
Sbjct: 195 GIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARI 254
Query: 155 KIPQILADPWLN 120
IP I D W N
Sbjct: 255 TIPDIKKDRWYN 266
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 128 bits (310), Expect = 2e-29
Identities = 84/252 (33%), Positives = 129/252 (51%), Gaps = 3/252 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y V++A + VA+KI+ +A + + +EI + K L HEN+++F
Sbjct: 19 AYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRRE 76
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENL
Sbjct: 77 GNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENL 136
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS
Sbjct: 137 LLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSC 194
Query: 326 GVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRV 156
G+VL A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+
Sbjct: 195 GIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARI 254
Query: 155 KIPQILADPWLN 120
IP I D W N
Sbjct: 255 TIPDIKKDRWYN 266
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 128 bits (310), Expect = 2e-29
Identities = 84/252 (33%), Positives = 129/252 (51%), Gaps = 3/252 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y V++A + VA+KI+ +A + + +EI + K L HEN+++F
Sbjct: 19 AYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRRE 76
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENL
Sbjct: 77 GNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENL 136
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS
Sbjct: 137 LLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSC 194
Query: 326 GVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRV 156
G+VL A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+
Sbjct: 195 GIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARI 254
Query: 155 KIPQILADPWLN 120
IP I D W N
Sbjct: 255 TIPDIKKDRWYN 266
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 128 bits (310), Expect = 2e-29
Identities = 84/252 (33%), Positives = 129/252 (51%), Gaps = 3/252 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y V++A + VA+KI+ +A + + +EI + K L HEN+++F
Sbjct: 19 AYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRRE 76
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENL
Sbjct: 77 GNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENL 136
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS
Sbjct: 137 LLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSC 194
Query: 326 GVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRV 156
G+VL A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+
Sbjct: 195 GIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARI 254
Query: 155 KIPQILADPWLN 120
IP I D W N
Sbjct: 255 TIPDIKKDRWYN 266
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 128 bits (310), Expect = 2e-29
Identities = 84/252 (33%), Positives = 129/252 (51%), Gaps = 3/252 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y V++A + VA+KI+ +A + + +EI + K L HEN+++F
Sbjct: 19 AYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRRE 76
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENL
Sbjct: 77 GNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENL 136
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS
Sbjct: 137 LLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSC 194
Query: 326 GVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRV 156
G+VL A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+
Sbjct: 195 GIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARI 254
Query: 155 KIPQILADPWLN 120
IP I D W N
Sbjct: 255 TIPDIKKDRWYN 266
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 128 bits (310), Expect = 2e-29
Identities = 84/252 (33%), Positives = 129/252 (51%), Gaps = 3/252 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+Y V++A + VA+KI+ +A + + +EI + K L HEN+++F
Sbjct: 19 AYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVVKFYGHRRE 76
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENL
Sbjct: 77 GNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENL 136
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L+D N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS
Sbjct: 137 LLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSC 194
Query: 326 GVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRV 156
G+VL A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+
Sbjct: 195 GIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARI 254
Query: 155 KIPQILADPWLN 120
IP I D W N
Sbjct: 255 TIPDIKKDRWYN 266
>AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein.
Length = 347
Score = 128 bits (308), Expect = 3e-29
Identities = 78/268 (29%), Positives = 138/268 (51%), Gaps = 4/268 (1%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + + VA+K++ K Q + ++ L REIE+ L H N++R
Sbjct: 88 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDR 147
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRG---RRWFKQLVEAVDYCHERGVVHRDIKCE 513
R+Y+++EYA G L + K DE R RR ++L +A+ YCH + V+HRDIK E
Sbjct: 148 RRIYLILEYAPRGMLYKELHKTCTFDEQRTATVRRIMEELADALMYCHGKKVIHRDIKPE 207
Query: 512 NLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 333
NLL+ +K++DFG++ + +T CG+ Y PE+++G + + D+W
Sbjct: 208 NLLLGLKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLW 260
Query: 332 SMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRV 156
+GV+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+
Sbjct: 261 CIGVLCYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERL 319
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHA 72
+ Q+ A PW+ N + + LQ A
Sbjct: 320 PLAQVSAHPWVRANSRRVLPPSALQSVA 347
>AB183428-1|BAF73616.1| 580|Homo sapiens maternal embryonic luecine
zipper kinase v3 protein.
Length = 580
Score = 128 bits (308), Expect = 3e-29
Identities = 70/182 (38%), Positives = 100/182 (54%), Gaps = 2/182 (1%)
Frame = -3
Query: 662 EYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNI 483
+Y G L D I + E R F+Q+V AV Y H +G HRD+K ENLL D +
Sbjct: 16 QYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKL 75
Query: 482 KLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIV 303
KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG++LY ++
Sbjct: 76 KLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLM 132
Query: 302 YGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADP 129
G LPFDD N L K++ + K P+ +S L+ ++L K R+ + +L P
Sbjct: 133 CGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISMKNLLNHP 190
Query: 128 WL 123
W+
Sbjct: 191 WI 192
>AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase
protein.
Length = 347
Score = 126 bits (304), Expect = 1e-28
Identities = 77/268 (28%), Positives = 138/268 (51%), Gaps = 4/268 (1%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + + VA+K++ K Q + ++ L REIE+ L H N++R
Sbjct: 88 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDR 147
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRG---RRWFKQLVEAVDYCHERGVVHRDIKCE 513
R+Y+++EYA G L ++K DE R R ++L +A+ YCH + V+HRDIK E
Sbjct: 148 RRIYLILEYAPRGMLYKELQKSCTFDEQRTATVRAVMEELADALMYCHGKKVIHRDIKPE 207
Query: 512 NLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 333
NLL+ +K++DFG++ + +T CG+ Y PE+++G + + D+W
Sbjct: 208 NLLLGLKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLW 260
Query: 332 SMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRV 156
+GV+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+
Sbjct: 261 CIGVLCYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERL 319
Query: 155 KIPQILADPWLNPNQQSKHDETDLQEHA 72
+ Q+ A PW+ N + + LQ A
Sbjct: 320 PLAQVSAHPWVRANSRRVLPPSALQSVA 347
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 126 bits (304), Expect = 1e-28
Identities = 76/265 (28%), Positives = 136/265 (51%), Gaps = 1/265 (0%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + + VA+K++ K Q + ++ L REIE+ L H N++R
Sbjct: 88 FGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDR 147
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
R+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL
Sbjct: 148 RRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLL 207
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + +T CG+ Y PE+++G + D+W +G
Sbjct: 208 LGLKGELKIADFGWS------VHATSLRRKTMCGTLDYLPPEMIEG-RIDNEKVDLWCIG 260
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIP 147
V+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+ +
Sbjct: 261 VLCYELLVGN-PFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLA 318
Query: 146 QILADPWLNPNQQSKHDETDLQEHA 72
Q+ A PW+ N + + LQ A
Sbjct: 319 QVSAHPWVRANSRRVLPPSALQSVA 343
>U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kinase
homolog protein.
Length = 174
Score = 126 bits (303), Expect = 1e-28
Identities = 65/178 (36%), Positives = 103/178 (57%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++ VKV + +VA+KI+++ + + + REI+ +K +H ++I+ Q I T
Sbjct: 2 AFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVIST 61
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+++VMEY G L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN+
Sbjct: 62 PSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENV 121
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 333
L+D +N K++DFG + +G F T CGS YA+PE++ G Y + D+W
Sbjct: 122 LLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYVGPEVDLW 174
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 123 bits (296), Expect = 1e-27
Identities = 80/234 (34%), Positives = 122/234 (52%), Gaps = 2/234 (0%)
Frame = -3
Query: 818 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 639
VA+K I K L+ L REIE+++GL+H N++ L + ET V +V +YAE G L
Sbjct: 30 VALKFIPKLGRSEKELRN-LQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GEL 87
Query: 638 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 459
I+ D + E + + QLV A+ Y H ++HRD+K +N+L+ G IKL DFGFA
Sbjct: 88 FQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFA 147
Query: 458 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD 279
R M V + G+ Y SPE+++ PY +D+WS+G +LY + G PF
Sbjct: 148 RA-MSTNTMVLT---SIKGTPLYMSPELVEERPY-DHTADLWSVGCILYELAVGTPPFYA 202
Query: 278 TNYTQLLKQVQNKVSFPREPKVSAECRK--LITRILAPLKMRVKIPQILADPWL 123
T+ QL+ + R P + C K L + + R+ P +L P++
Sbjct: 203 TSIFQLVSLILKDP--VRWPSTISPCFKDFLQGLLTKDPRQRLSWPDLLYHPFI 254
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 123 bits (296), Expect = 1e-27
Identities = 80/234 (34%), Positives = 122/234 (52%), Gaps = 2/234 (0%)
Frame = -3
Query: 818 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 639
VA+K I K L+ L REIE+++GL+H N++ L + ET V +V +YAE G L
Sbjct: 30 VALKFIPKLGRSEKELRN-LQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GEL 87
Query: 638 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 459
I+ D + E + + QLV A+ Y H ++HRD+K +N+L+ G IKL DFGFA
Sbjct: 88 FQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFA 147
Query: 458 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD 279
R M V + G+ Y SPE+++ PY +D+WS+G +LY + G PF
Sbjct: 148 RA-MSTNTMVLT---SIKGTPLYMSPELVEERPY-DHTADLWSVGCILYELAVGTPPFYA 202
Query: 278 TNYTQLLKQVQNKVSFPREPKVSAECRK--LITRILAPLKMRVKIPQILADPWL 123
T+ QL+ + R P + C K L + + R+ P +L P++
Sbjct: 203 TSIFQLVSLILKDP--VRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFI 254
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 123 bits (296), Expect = 1e-27
Identities = 80/234 (34%), Positives = 122/234 (52%), Gaps = 2/234 (0%)
Frame = -3
Query: 818 VAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 639
VA+K I K L+ L REIE+++GL+H N++ L + ET V +V +YAE G L
Sbjct: 47 VALKFIPKLGRSEKELRN-LQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GEL 104
Query: 638 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFA 459
I+ D + E + + QLV A+ Y H ++HRD+K +N+L+ G IKL DFGFA
Sbjct: 105 FQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFA 164
Query: 458 RGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD 279
R M V + G+ Y SPE+++ PY +D+WS+G +LY + G PF
Sbjct: 165 RA-MSTNTMVLT---SIKGTPLYMSPELVEERPY-DHTADLWSVGCILYELAVGTPPFYA 219
Query: 278 TNYTQLLKQVQNKVSFPREPKVSAECRK--LITRILAPLKMRVKIPQILADPWL 123
T+ QL+ + R P + C K L + + R+ P +L P++
Sbjct: 220 TSIFQLVSLILKDP--VRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFI 271
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 122 bits (295), Expect = 1e-27
Identities = 72/231 (31%), Positives = 129/231 (55%), Gaps = 1/231 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S++TV +A + + AIKI+ K + ++ RE +V+ L H ++ +
Sbjct: 92 SFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQD 151
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+
Sbjct: 152 DEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENI 211
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++
Sbjct: 212 LLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWAL 268
Query: 326 GVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 177
G ++Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 269 GCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 317
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 122 bits (295), Expect = 1e-27
Identities = 72/231 (31%), Positives = 129/231 (55%), Gaps = 1/231 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S++TV +A + + AIKI+ K + ++ RE +V+ L H ++ +
Sbjct: 92 SFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQD 151
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+
Sbjct: 152 DEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENI 211
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++
Sbjct: 212 LLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWAL 268
Query: 326 GVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 177
G ++Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 269 GCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 317
>BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein.
Length = 1102
Score = 122 bits (295), Expect = 1e-27
Identities = 71/164 (43%), Positives = 95/164 (57%), Gaps = 3/164 (1%)
Frame = -3
Query: 605 ETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVF 426
E RR FKQ+V AV +CH R +VHRD+K ENLL+D LNIK++DFGF+ +
Sbjct: 3 EKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ---- 58
Query: 425 ALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV- 249
L +T+CGS YA+PE+ +G Y D+WS+GVVLY +V G LPFD + L +V
Sbjct: 59 -LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVL 117
Query: 248 QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIPQILADPWL 123
K P +S EC LI +L P K R+ + QI W+
Sbjct: 118 SGKFRIPF--FMSTECEHLIRHMLVLDPNK-RLSMEQICKHKWM 158
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 122 bits (295), Expect = 1e-27
Identities = 72/231 (31%), Positives = 129/231 (55%), Gaps = 1/231 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S++TV +A + + AIKI+ K + ++ RE +V+ L H ++ +
Sbjct: 92 SFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQD 151
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+
Sbjct: 152 DEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENI 211
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++
Sbjct: 212 LLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWAL 268
Query: 326 GVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 177
G ++Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 269 GCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 317
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 122 bits (295), Expect = 1e-27
Identities = 75/251 (29%), Positives = 136/251 (54%), Gaps = 12/251 (4%)
Frame = -3
Query: 836 DRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEY 657
++H+ +VA+K I+K + L +EI+++K LKHEN++ E + VY+VMEY
Sbjct: 37 EKHDLEVAVKCINKKNLAKS--QTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEY 94
Query: 656 AENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD------- 498
G L D + + + E R + +Q+ A+ H +G++HRD+K +N+L+
Sbjct: 95 CNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRA 154
Query: 497 --HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ + +K++DFGFAR +++ ++ T CGS Y +PE++ Y + +D+WS+G
Sbjct: 155 NPNSIRVKIADFGFAR-YLQSN----MMAATLCGSPMYMAPEVIMSQHYDGK-ADLWSIG 208
Query: 323 VVLYAIVYGRLPFDDTNYTQL-LKQVQNKVSFPREPK-VSAECRKLITRIL-APLKMRVK 153
++Y + G+ PF ++ L L +NK P P+ SA R+L+ +L K R+
Sbjct: 209 TIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMD 268
Query: 152 IPQILADPWLN 120
+ P+L+
Sbjct: 269 FDEFFHHPFLD 279
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 122 bits (295), Expect = 1e-27
Identities = 72/231 (31%), Positives = 129/231 (55%), Gaps = 1/231 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S++TV +A + + AIKI+ K + ++ RE +V+ L H ++ +
Sbjct: 92 SFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQD 151
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+
Sbjct: 152 DEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENI 211
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++
Sbjct: 212 LLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWAL 268
Query: 326 GVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 177
G ++Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 269 GCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 317
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 122 bits (295), Expect = 1e-27
Identities = 72/231 (31%), Positives = 129/231 (55%), Gaps = 1/231 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S++TV +A + + AIKI+ K + ++ RE +V+ L H ++ +
Sbjct: 84 SFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQD 143
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+
Sbjct: 144 DEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENI 203
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++
Sbjct: 204 LLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWAL 260
Query: 326 GVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 177
G ++Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 261 GCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 309
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 122 bits (295), Expect = 1e-27
Identities = 72/231 (31%), Positives = 129/231 (55%), Gaps = 1/231 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S++TV +A + + AIKI+ K + ++ RE +V+ L H ++ +
Sbjct: 130 SFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQD 189
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+
Sbjct: 190 DEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENI 249
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++
Sbjct: 250 LLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWAL 306
Query: 326 GVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 177
G ++Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 307 GCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 355
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 122 bits (295), Expect = 1e-27
Identities = 75/251 (29%), Positives = 136/251 (54%), Gaps = 12/251 (4%)
Frame = -3
Query: 836 DRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEY 657
++H+ +VA+K I+K + L +EI+++K LKHEN++ E + VY+VMEY
Sbjct: 53 EKHDLEVAVKCINKKNLAKS--QTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEY 110
Query: 656 AENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD------- 498
G L D + + + E R + +Q+ A+ H +G++HRD+K +N+L+
Sbjct: 111 CNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRA 170
Query: 497 --HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ + +K++DFGFAR +++ ++ T CGS Y +PE++ Y + +D+WS+G
Sbjct: 171 NPNSIRVKIADFGFAR-YLQSN----MMAATLCGSPMYMAPEVIMSQHYDGK-ADLWSIG 224
Query: 323 VVLYAIVYGRLPFDDTNYTQL-LKQVQNKVSFPREPK-VSAECRKLITRIL-APLKMRVK 153
++Y + G+ PF ++ L L +NK P P+ SA R+L+ +L K R+
Sbjct: 225 TIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMD 284
Query: 152 IPQILADPWLN 120
+ P+L+
Sbjct: 285 FDEFFHHPFLD 295
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 121 bits (292), Expect = 3e-27
Identities = 72/231 (31%), Positives = 128/231 (55%), Gaps = 1/231 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S++TV +A + + AIKI+ K + ++ RE +V+ L H ++ +
Sbjct: 92 SFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQD 151
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y + YA+NG LL IRK DET R + ++V A +Y H +G++HRD+K EN+
Sbjct: 152 DEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSASEYLHGKGIIHRDLKPENI 211
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L++ ++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++
Sbjct: 212 LLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWAL 268
Query: 326 GVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 177
G ++Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 269 GCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 317
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 121 bits (292), Expect = 3e-27
Identities = 72/231 (31%), Positives = 128/231 (55%), Gaps = 1/231 (0%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S++TV +A + + AIKI+ K + ++ RE +V+ L H ++ +
Sbjct: 65 SFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQD 124
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
++Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+
Sbjct: 125 DEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENI 184
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 327
L++ + I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++
Sbjct: 185 LLNEDMYIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWAL 241
Query: 326 GVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 177
G ++Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 242 GCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 290
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 121 bits (291), Expect = 4e-27
Identities = 62/205 (30%), Positives = 110/205 (53%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETT 684
+ V +A + +A+K++ K Q ++ L RE+E+ L+H N++R
Sbjct: 144 FGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDA 203
Query: 683 HRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 504
RVY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL
Sbjct: 204 TRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLL 263
Query: 503 MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 324
+ +K++DFG++ + + T CG+ Y PE+++G + D+WS+G
Sbjct: 264 LGSAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLG 316
Query: 323 VVLYAIVYGRLPFDDTNYTQLLKQV 249
V+ Y + G+ PF+ Y + K++
Sbjct: 317 VLCYEFLVGKPPFEANTYQETYKRI 341
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 120 bits (290), Expect = 5e-27
Identities = 78/243 (32%), Positives = 127/243 (52%), Gaps = 4/243 (1%)
Frame = -3
Query: 839 SDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVME 660
SD +C IK I+ F+ K+ +E+ +++ +KH N++ F + + R++IVME
Sbjct: 25 SDSKHC--VIKEIN-FEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVME 81
Query: 659 YAENGSLLDIIRKDQHI--DETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL-LMDHGL 489
Y + G L+ I + + + E + WF Q+ + + H+R ++HRDIK +N+ L +G+
Sbjct: 82 YCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGM 141
Query: 488 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYA 309
KL DFG AR N L+ T G+ Y SPEI + PY +D+WS+G VLY
Sbjct: 142 VAKLGDFGIAR----VLNNSMELARTCIGTPYYLSPEICQNKPYN-NKTDIWSLGCVLYE 196
Query: 308 IVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQILAD 132
+ + PF+ N QL+ ++ P P S E LI+++ + R I IL
Sbjct: 197 LCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKR 256
Query: 131 PWL 123
P+L
Sbjct: 257 PFL 259
>BC043487-1|AAH43487.1| 505|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 1,
alpha protein.
Length = 505
Score = 120 bits (290), Expect = 5e-27
Identities = 74/260 (28%), Positives = 139/260 (53%), Gaps = 12/260 (4%)
Frame = -3
Query: 788 APGDYLKKFLP-----REIEVVKGLKHENLIRFLQAIE--TTHRVYIVMEYAENGSLLDI 630
A G K+ LP +EI ++K L H N+++ ++ ++ +Y+V + G ++++
Sbjct: 182 AQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEV 241
Query: 629 IRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGH 450
D+ E + R + + ++ ++Y H + +VHRDIK NLL+ ++K++DFG +
Sbjct: 242 -PCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF 300
Query: 449 MKPKNGVFALSETFCGSYAYASPEIL--KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDT 276
G A + G+ A+ +PE + G + + DVW+ GV LY VYG+ PF D
Sbjct: 301 ----EGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDD 356
Query: 275 NYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWLNPN-QQS 105
L ++++N+ V FP EP++S E + LI ++L + R+ +P I PW+ N ++
Sbjct: 357 FILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEP 416
Query: 104 KHDETDLQEHAKTSKEEIKS 45
E + + ++EE+K+
Sbjct: 417 LPSEEEHCSVVEVTEEEVKN 436
>BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein.
Length = 207
Score = 120 bits (290), Expect = 5e-27
Identities = 62/167 (37%), Positives = 98/167 (58%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++ VKV + +VA+KI+++ + + + REI+ +K +H ++I+ Q I T
Sbjct: 28 TFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVIST 87
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+++VMEY G L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN+
Sbjct: 88 PSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENV 147
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKG 366
L+D +N K++DFG + +G F T CGS YA+PE++ G
Sbjct: 148 LLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISG 189
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 120 bits (290), Expect = 5e-27
Identities = 78/243 (32%), Positives = 127/243 (52%), Gaps = 4/243 (1%)
Frame = -3
Query: 839 SDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVME 660
SD +C IK I+ F+ K+ +E+ +++ +KH N++ F + + R++IVME
Sbjct: 25 SDSKHC--VIKEIN-FEKMPIQEKEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVME 81
Query: 659 YAENGSLLDIIRKDQHI--DETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL-LMDHGL 489
Y + G L+ I + + + E + WF Q+ + + H+R ++HRDIK +N+ L +G+
Sbjct: 82 YCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGM 141
Query: 488 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYA 309
KL DFG AR N L+ T G+ Y SPEI + PY +D+WS+G VLY
Sbjct: 142 VAKLGDFGIAR----VLNNSMELARTCIGTPYYLSPEICQNKPYN-NKTDIWSLGCVLYE 196
Query: 308 IVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQILAD 132
+ + PF+ N QL+ ++ P P S E LI+++ + R I IL
Sbjct: 197 LCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKR 256
Query: 131 PWL 123
P+L
Sbjct: 257 PFL 259
>AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein
protein.
Length = 505
Score = 120 bits (290), Expect = 5e-27
Identities = 74/260 (28%), Positives = 139/260 (53%), Gaps = 12/260 (4%)
Frame = -3
Query: 788 APGDYLKKFLP-----REIEVVKGLKHENLIRFLQAIE--TTHRVYIVMEYAENGSLLDI 630
A G K+ LP +EI ++K L H N+++ ++ ++ +Y+V + G ++++
Sbjct: 182 AQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEV 241
Query: 629 IRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGH 450
D+ E + R + + ++ ++Y H + +VHRDIK NLL+ ++K++DFG +
Sbjct: 242 -PCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF 300
Query: 449 MKPKNGVFALSETFCGSYAYASPEIL--KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDT 276
G A + G+ A+ +PE + G + + DVW+ GV LY VYG+ PF D
Sbjct: 301 ----EGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDD 356
Query: 275 NYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWLNPN-QQS 105
L ++++N+ V FP EP++S E + LI ++L + R+ +P I PW+ N ++
Sbjct: 357 FILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEP 416
Query: 104 KHDETDLQEHAKTSKEEIKS 45
E + + ++EE+K+
Sbjct: 417 LPSEEEHCSVVEVTEEEVKN 436
>AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein
protein.
Length = 505
Score = 120 bits (290), Expect = 5e-27
Identities = 74/260 (28%), Positives = 139/260 (53%), Gaps = 12/260 (4%)
Frame = -3
Query: 788 APGDYLKKFLP-----REIEVVKGLKHENLIRFLQAIE--TTHRVYIVMEYAENGSLLDI 630
A G K+ LP +EI ++K L H N+++ ++ ++ +Y+V + G ++++
Sbjct: 182 AQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEV 241
Query: 629 IRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGH 450
D+ E + R + + ++ ++Y H + +VHRDIK NLL+ ++K++DFG +
Sbjct: 242 -PCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF 300
Query: 449 MKPKNGVFALSETFCGSYAYASPEIL--KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDT 276
G A + G+ A+ +PE + G + + DVW+ GV LY VYG+ PF D
Sbjct: 301 ----EGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDD 356
Query: 275 NYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWLNPN-QQS 105
L ++++N+ V FP EP++S E + LI ++L + R+ +P I PW+ N ++
Sbjct: 357 FILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEP 416
Query: 104 KHDETDLQEHAKTSKEEIKS 45
E + + ++EE+K+
Sbjct: 417 LPSEEEHCSVVEVTEEEVKN 436
>AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta protein.
Length = 588
Score = 120 bits (290), Expect = 5e-27
Identities = 78/277 (28%), Positives = 147/277 (53%), Gaps = 29/277 (10%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQ------------------APGDYLKKFLP----- 756
SY VK+A ++ N A+K++SK + APG ++ P
Sbjct: 175 SYGVVKLAYNENDNTYYAMKVLSKKKLIRQAAFPRRPPPRGTRPAPGGCIQPRGPIEQVY 234
Query: 755 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 582
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 581 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 402
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL + G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNYVG 349
Query: 401 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 231
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKAKDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 230 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kinase 2,
skeletal muscle protein.
Length = 596
Score = 120 bits (288), Expect = 9e-27
Identities = 92/281 (32%), Positives = 141/281 (50%), Gaps = 8/281 (2%)
Frame = -3
Query: 821 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 642
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 641 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 471
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 470 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 291
FG AR + N L F G+ + SPE++ +D+WSMGV+ Y ++ G
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLS 480
Query: 290 PFDDTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 123
PF + T+ L V F E VS E + ++ I+ + R+ Q LA PWL
Sbjct: 481 PFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWL 540
Query: 122 NPNQQSKHDETDLQEHAKTSKEEIKS-VNIGTVTYDRKWKK 3
N +L E AK +KS + + R+WKK
Sbjct: 541 N----------NLAEKAKRCNRRLKSQILLKKYLMKRRWKK 571
>BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kinase 2,
skeletal muscle protein.
Length = 596
Score = 120 bits (288), Expect = 9e-27
Identities = 92/281 (32%), Positives = 141/281 (50%), Gaps = 8/281 (2%)
Frame = -3
Query: 821 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 642
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 641 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 471
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 470 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 291
FG AR + N L F G+ + SPE++ +D+WSMGV+ Y ++ G
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLS 480
Query: 290 PFDDTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 123
PF + T+ L V F E VS E + ++ I+ + R+ Q LA PWL
Sbjct: 481 PFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWL 540
Query: 122 NPNQQSKHDETDLQEHAKTSKEEIKS-VNIGTVTYDRKWKK 3
N +L E AK +KS + + R+WKK
Sbjct: 541 N----------NLAEKAKRCNRRLKSQILLKKYLMKRRWKK 571
>BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light chain
kinase protein.
Length = 596
Score = 120 bits (288), Expect = 9e-27
Identities = 92/281 (32%), Positives = 141/281 (50%), Gaps = 8/281 (2%)
Frame = -3
Query: 821 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 642
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 641 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 471
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 470 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 291
FG AR + N L F G+ + SPE++ +D+WSMGV+ Y ++ G
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLS 480
Query: 290 PFDDTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 123
PF + T+ L V F E VS E + ++ I+ + R+ Q LA PWL
Sbjct: 481 PFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWL 540
Query: 122 NPNQQSKHDETDLQEHAKTSKEEIKS-VNIGTVTYDRKWKK 3
N +L E AK +KS + + R+WKK
Sbjct: 541 N----------NLAEKAKRCNRRLKSQILLKKYLMKRRWKK 571
>AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kinase
2, skeletal muscle protein.
Length = 596
Score = 120 bits (288), Expect = 9e-27
Identities = 92/281 (32%), Positives = 141/281 (50%), Gaps = 8/281 (2%)
Frame = -3
Query: 821 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 642
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 641 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 471
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 470 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 291
FG AR + N L F G+ + SPE++ +D+WSMGV+ Y ++ G
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLS 480
Query: 290 PFDDTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 123
PF + T+ L V F E VS E + ++ I+ + R+ Q LA PWL
Sbjct: 481 PFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWL 540
Query: 122 NPNQQSKHDETDLQEHAKTSKEEIKS-VNIGTVTYDRKWKK 3
N +L E AK +KS + + R+WKK
Sbjct: 541 N----------NLAEKAKRCNRRLKSQILLKKYLMKRRWKK 571
>AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens
cDNA FLJ16039 fis, clone ADRGL2001554, weakly similar
to SERINE/THREONINE-PROTEIN KINASE PLK (EC 2.7.1.-). ).
Length = 706
Score = 120 bits (288), Expect = 9e-27
Identities = 71/252 (28%), Positives = 134/252 (53%), Gaps = 6/252 (2%)
Frame = -3
Query: 863 YATVKVASSDRHNCQVAIKIISKFQ-APGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+A V +S R + A K++ K YL+KF+ EI + + L H ++ + + E
Sbjct: 50 FAIVYELTSIRTGKKYAGKVVEKAGLTKPKYLEKFMS-EIRIHQSLDHPHICKMYKHFED 108
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
Y+++E N +L ++R + + E + + Q+++AV Y H+R ++HRD+K N+
Sbjct: 109 NRYHYLILELCSNETLAHLLRVRECLTEPEVQYFLLQIIDAVSYLHKRCIIHRDLKLGNI 168
Query: 506 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR--PQDSDVW 333
+D L +K+ D G A +P +T CG+ Y +PEIL+ R + D+W
Sbjct: 169 FLDENLEVKVGDLGLAAQLNEPNE----RKKTMCGTPNYIAPEILQSNDKRAYSYEVDIW 224
Query: 332 SMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP-REPKVSAECRKLITRILAP-LKM 162
++GV+ Y ++ G+ PFD + +++ +N++SFP ++ +S + R I IL P
Sbjct: 225 AVGVITYTMLIGKAPFDGGSKEITYRKIRENELSFPIKDHHISHQARMFIRSILNPDPTQ 284
Query: 161 RVKIPQILADPW 126
R+ + Q++ P+
Sbjct: 285 RLTLEQMVQHPF 296
>AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specific
myosin light chain kinase protein.
Length = 596
Score = 120 bits (288), Expect = 9e-27
Identities = 92/281 (32%), Positives = 141/281 (50%), Gaps = 8/281 (2%)
Frame = -3
Query: 821 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 642
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 641 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 471
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 470 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 291
FG AR + N L F G+ + SPE++ +D+WSMGV+ Y ++ G
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLS 480
Query: 290 PFDDTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 123
PF + T+ L V F E VS E + ++ I+ + R+ Q LA PWL
Sbjct: 481 PFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWL 540
Query: 122 NPNQQSKHDETDLQEHAKTSKEEIKS-VNIGTVTYDRKWKK 3
N +L E AK +KS + + R+WKK
Sbjct: 541 N----------NLAEKAKRCNRRLKSQILLKKYLMKRRWKK 571
>AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light chain
kinase protein.
Length = 596
Score = 120 bits (288), Expect = 9e-27
Identities = 92/281 (32%), Positives = 141/281 (50%), Gaps = 8/281 (2%)
Frame = -3
Query: 821 QVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGS 642
++A K+I K Q P D K+ + EIEV+ L H NLI+ AIET H + + MEY E G
Sbjct: 310 KLAAKVIKK-QTPKD--KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGE 366
Query: 641 LLD-IIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSD 471
L + I+ +D H+ E + +Q+ + + + H+ V+H D+K EN+L + G +K+ D
Sbjct: 367 LFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIID 426
Query: 470 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 291
FG AR + N L F G+ + SPE++ +D+WSMGV+ Y ++ G
Sbjct: 427 FGLARRY----NPNEKLKVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLS 480
Query: 290 PFDDTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 123
PF + T+ L V F E VS E + ++ I+ + R+ Q LA PWL
Sbjct: 481 PFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWL 540
Query: 122 NPNQQSKHDETDLQEHAKTSKEEIKS-VNIGTVTYDRKWKK 3
N +L E AK +KS + + R+WKK
Sbjct: 541 N----------NLAEKAKRCNRRLKSQILLKKYLMKRRWKK 571
>BC040457-1|AAH40457.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II alpha protein.
Length = 478
Score = 119 bits (286), Expect = 2e-26
Identities = 81/243 (33%), Positives = 127/243 (52%), Gaps = 9/243 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y++ + G
Sbjct: 38 EYAAKIINTKKLSARDHQK--LEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGG 95
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 96 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLA 155
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G
Sbjct: 156 DFGLAIEVEGEQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGY 210
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L KQ++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 211 PPFWDEDQHRLYKQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK-RITAAEALKHP 269
Query: 128 WLN 120
W++
Sbjct: 270 WIS 272
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 119 bits (286), Expect = 2e-26
Identities = 77/260 (29%), Positives = 130/260 (50%), Gaps = 5/260 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S+A V A S +VAIK+I K + + + E+++ LKH +++ E
Sbjct: 22 SFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFED 81
Query: 686 THRVYIVMEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
++ VY+V+E NG + ++ + + E R + Q++ + Y H G++HRD+ N
Sbjct: 82 SNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSN 141
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
LL+ +NIK++DFG A P + T CG+ Y SPEI + +SDVWS
Sbjct: 142 LLLTRNMNIKIADFGLATQLKMPHEKHY----TLCGTPNYISPEIATRSAH-GLESDVWS 196
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSAECRKLITRILAPLKM- 162
+G + Y ++ GR PFD T +K NKV + +S E + LI ++L
Sbjct: 197 LGCMFYTLLIGRPPFD----TDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLRRNPAD 252
Query: 161 RVKIPQILADPWLNPNQQSK 102
R+ + +L P+++ N +K
Sbjct: 253 RLSLSSVLDHPFMSRNSSTK 272
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 118 bits (285), Expect = 2e-26
Identities = 77/260 (29%), Positives = 130/260 (50%), Gaps = 5/260 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S+A V A S +VAIK+I K + + + E+++ LKH +++ E
Sbjct: 22 SFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHPSILELYNYFED 81
Query: 686 THRVYIVMEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
++ VY+V+E NG + ++ + + E R + Q++ + Y H G++HRD+ N
Sbjct: 82 SNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSN 141
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
LL+ +NIK++DFG A P + T CG+ Y SPEI + +SDVWS
Sbjct: 142 LLLTRNMNIKIADFGLATQLKMPHEKHY----TLCGTPNYISPEIATRSAH-GLESDVWS 196
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSAECRKLITRILAPLKM- 162
+G + Y ++ GR PFD T +K NKV + +S E + LI ++L
Sbjct: 197 LGCMFYTLLIGRPPFD----TDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLRRNPAD 252
Query: 161 RVKIPQILADPWLNPNQQSK 102
R+ + +L P+++ N +K
Sbjct: 253 RLSLSSVLDHPFMSRNSSTK 272
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 118 bits (285), Expect = 2e-26
Identities = 67/193 (34%), Positives = 112/193 (58%), Gaps = 1/193 (0%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 573
E V++ +H L A +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 200 ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEI 259
Query: 572 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 393
V A++Y H R VV+RDIK ENL++D +IK++DFG + + +G A +TFCG+
Sbjct: 260 VSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFCGTPE 315
Query: 392 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 216
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 316 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR--T 372
Query: 215 VSAECRKLITRIL 177
+S E + L+ +L
Sbjct: 373 LSPEAKSLLAGLL 385
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 118 bits (285), Expect = 2e-26
Identities = 67/193 (34%), Positives = 112/193 (58%), Gaps = 1/193 (0%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 573
E V++ +H L A +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 200 ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEI 259
Query: 572 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 393
V A++Y H R VV+RDIK ENL++D +IK++DFG + + +G A +TFCG+
Sbjct: 260 VSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFCGTPE 315
Query: 392 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 216
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 316 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR--T 372
Query: 215 VSAECRKLITRIL 177
+S E + L+ +L
Sbjct: 373 LSPEAKSLLAGLL 385
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 118 bits (285), Expect = 2e-26
Identities = 67/193 (34%), Positives = 112/193 (58%), Gaps = 1/193 (0%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 573
E V++ +H L A +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 200 ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEI 259
Query: 572 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 393
V A++Y H R VV+RDIK ENL++D +IK++DFG + + +G A +TFCG+
Sbjct: 260 VSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFCGTPE 315
Query: 392 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 216
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 316 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR--T 372
Query: 215 VSAECRKLITRIL 177
+S E + L+ +L
Sbjct: 373 LSPEAKSLLAGLL 385
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 118 bits (285), Expect = 2e-26
Identities = 77/260 (29%), Positives = 130/260 (50%), Gaps = 5/260 (1%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
S+A V A S +VAIK+I K + + + E+++ LKH +++ E
Sbjct: 22 SFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFED 81
Query: 686 THRVYIVMEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
++ VY+V+E NG + ++ + + E R + Q++ + Y H G++HRD+ N
Sbjct: 82 SNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSN 141
Query: 509 LLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 330
LL+ +NIK++DFG A P + T CG+ Y SPEI + +SDVWS
Sbjct: 142 LLLTRNMNIKIADFGLATQLKMPHEKHY----TLCGTPNYISPEIATRSAH-GLESDVWS 196
Query: 329 MGVVLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSAECRKLITRILAPLKM- 162
+G + Y ++ GR PFD T +K NKV + +S E + LI ++L
Sbjct: 197 LGCMFYTLLIGRPPFD----TDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPAD 252
Query: 161 RVKIPQILADPWLNPNQQSK 102
R+ + +L P+++ N +K
Sbjct: 253 RLSLSSVLDHPFMSRNSSTK 272
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 118 bits (284), Expect = 3e-26
Identities = 81/242 (33%), Positives = 126/242 (52%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAK-RITASEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WI 272
>BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing
serine/threonine kinase protein.
Length = 1323
Score = 118 bits (283), Expect = 4e-26
Identities = 71/212 (33%), Positives = 114/212 (53%), Gaps = 2/212 (0%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 576
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 1052 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 1111
Query: 575 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 396
LV AV Y + ++HRDIK EN+++ IKL DFG A + K L TFCG+
Sbjct: 1112 LVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 1166
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 216
Y +PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P
Sbjct: 1167 EYCAPEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--L 1219
Query: 215 VSAECRKLITRILAPL-KMRVKIPQILADPWL 123
VS E L++ +L P+ + R + +++ DPW+
Sbjct: 1220 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
>BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein.
Length = 953
Score = 118 bits (283), Expect = 4e-26
Identities = 71/212 (33%), Positives = 114/212 (53%), Gaps = 2/212 (0%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 576
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 682 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 741
Query: 575 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 396
LV AV Y + ++HRDIK EN+++ IKL DFG A + K L TFCG+
Sbjct: 742 LVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 796
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 216
Y +PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P
Sbjct: 797 EYCAPEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--L 849
Query: 215 VSAECRKLITRILAPL-KMRVKIPQILADPWL 123
VS E L++ +L P+ + R + +++ DPW+
Sbjct: 850 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 881
>BC026060-1|AAH26060.1| 541|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 2,
beta protein.
Length = 541
Score = 118 bits (283), Expect = 4e-26
Identities = 78/277 (28%), Positives = 146/277 (52%), Gaps = 29/277 (10%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQ------------------APGDYLKKFLP----- 756
SY VK+A ++ N A+K++SK + APG ++ P
Sbjct: 175 SYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVY 234
Query: 755 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 582
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 581 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 402
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 401 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 231
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 230 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein.
Length = 1323
Score = 118 bits (283), Expect = 4e-26
Identities = 71/212 (33%), Positives = 114/212 (53%), Gaps = 2/212 (0%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 576
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 1052 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 1111
Query: 575 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 396
LV AV Y + ++HRDIK EN+++ IKL DFG A + K L TFCG+
Sbjct: 1112 LVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 1166
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 216
Y +PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P
Sbjct: 1167 EYCAPEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--L 1219
Query: 215 VSAECRKLITRILAPL-KMRVKIPQILADPWL 123
VS E L++ +L P+ + R + +++ DPW+
Sbjct: 1220 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
>AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 1 protein.
Length = 588
Score = 118 bits (283), Expect = 4e-26
Identities = 78/277 (28%), Positives = 146/277 (52%), Gaps = 29/277 (10%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQ------------------APGDYLKKFLP----- 756
SY VK+A ++ N A+K++SK + APG ++ P
Sbjct: 175 SYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVY 234
Query: 755 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 582
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 581 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 402
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 401 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 231
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 230 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 2 protein.
Length = 533
Score = 118 bits (283), Expect = 4e-26
Identities = 78/277 (28%), Positives = 146/277 (52%), Gaps = 29/277 (10%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQ------------------APGDYLKKFLP----- 756
SY VK+A ++ N A+K++SK + APG ++ P
Sbjct: 175 SYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVY 234
Query: 755 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 582
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 581 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 402
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 401 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 231
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 230 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 541
Score = 118 bits (283), Expect = 4e-26
Identities = 78/277 (28%), Positives = 146/277 (52%), Gaps = 29/277 (10%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQ------------------APGDYLKKFLP----- 756
SY VK+A ++ N A+K++SK + APG ++ P
Sbjct: 175 SYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVY 234
Query: 755 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 582
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 581 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 402
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 401 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 231
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 230 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF287631-1|AAK64601.1| 533|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase b2
protein.
Length = 533
Score = 118 bits (283), Expect = 4e-26
Identities = 78/277 (28%), Positives = 146/277 (52%), Gaps = 29/277 (10%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQ------------------APGDYLKKFLP----- 756
SY VK+A ++ N A+K++SK + APG ++ P
Sbjct: 175 SYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVY 234
Query: 755 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 582
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 581 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 402
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 401 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 231
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 230 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF287630-1|AAK64600.1| 588|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase b1
protein.
Length = 588
Score = 118 bits (283), Expect = 4e-26
Identities = 78/277 (28%), Positives = 146/277 (52%), Gaps = 29/277 (10%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQ------------------APGDYLKKFLP----- 756
SY VK+A ++ N A+K++SK + APG ++ P
Sbjct: 175 SYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVY 234
Query: 755 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 582
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 581 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 402
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 401 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 231
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 230 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-dependent
kinase kinase protein.
Length = 417
Score = 118 bits (283), Expect = 4e-26
Identities = 78/277 (28%), Positives = 146/277 (52%), Gaps = 29/277 (10%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQ------------------APGDYLKKFLP----- 756
SY VK+A ++ N A+K++SK + APG ++ P
Sbjct: 59 SYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVY 118
Query: 755 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 582
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 119 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 177
Query: 581 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 402
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 178 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 233
Query: 401 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 231
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 234 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 293
Query: 230 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 294 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 330
>AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta-3 protein.
Length = 541
Score = 118 bits (283), Expect = 4e-26
Identities = 78/277 (28%), Positives = 146/277 (52%), Gaps = 29/277 (10%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQ------------------APGDYLKKFLP----- 756
SY VK+A ++ N A+K++SK + APG ++ P
Sbjct: 175 SYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVY 234
Query: 755 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 582
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 581 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 402
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 401 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 231
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 230 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein.
Length = 557
Score = 118 bits (283), Expect = 4e-26
Identities = 78/277 (28%), Positives = 146/277 (52%), Gaps = 29/277 (10%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQ------------------APGDYLKKFLP----- 756
SY VK+A ++ N A+K++SK + APG ++ P
Sbjct: 176 SYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVY 235
Query: 755 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 582
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 236 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 294
Query: 581 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 402
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 295 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 350
Query: 401 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 231
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 351 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 410
Query: 230 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 123
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 411 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 447
>AF145711-1|AAD30559.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha-B
subunit protein.
Length = 489
Score = 117 bits (282), Expect = 5e-26
Identities = 80/243 (32%), Positives = 127/243 (52%), Gaps = 9/243 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y++ + G
Sbjct: 38 EYAAKIINTKKLSARDHQK--LEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGG 95
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 96 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLA 155
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G
Sbjct: 156 DFGLAIEVEGEQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGY 210
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 211 PPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK-RITAAEALKHP 269
Query: 128 WLN 120
W++
Sbjct: 270 WIS 272
>AF145710-1|AAD30558.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha
subunit protein.
Length = 478
Score = 117 bits (282), Expect = 5e-26
Identities = 80/243 (32%), Positives = 127/243 (52%), Gaps = 9/243 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y++ + G
Sbjct: 38 EYAAKIINTKKLSARDHQK--LEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGG 95
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 96 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLA 155
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G
Sbjct: 156 DFGLAIEVEGEQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGY 210
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 211 PPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK-RITAAEALKHP 269
Query: 128 WLN 120
W++
Sbjct: 270 WIS 272
>AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent
protein kinase II alpha protein.
Length = 478
Score = 117 bits (282), Expect = 5e-26
Identities = 80/243 (32%), Positives = 127/243 (52%), Gaps = 9/243 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y++ + G
Sbjct: 38 EYAAKIINTKKLSARDHQK--LEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGG 95
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 96 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLA 155
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G
Sbjct: 156 DFGLAIEVEGEQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGY 210
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 211 PPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK-RITAAEALKHP 269
Query: 128 WLN 120
W++
Sbjct: 270 WIS 272
>AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein.
Length = 527
Score = 117 bits (282), Expect = 5e-26
Identities = 80/243 (32%), Positives = 127/243 (52%), Gaps = 9/243 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y++ + G
Sbjct: 87 EYAAKIINTKKLSARDHQK--LEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGG 144
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 145 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLA 204
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G
Sbjct: 205 DFGLAIEVEGEQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGY 259
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 260 PPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK-RITAAEALKHP 318
Query: 128 WLN 120
W++
Sbjct: 319 WIS 321
>U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine
protein kinase PRK protein.
Length = 607
Score = 117 bits (281), Expect = 6e-26
Identities = 65/227 (28%), Positives = 121/227 (53%), Gaps = 1/227 (0%)
Frame = -3
Query: 815 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 636
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 50 AVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 109
Query: 635 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 456
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 110 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 168
Query: 455 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDT 276
++P +T CG+ Y +PE+L + P ++DVWS+G V+Y ++ G PF+
Sbjct: 169 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLGCVMYTLLCGSPPFETA 224
Query: 275 NYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQIL 138
+ + + ++ +V + +S R+L+ IL A + R I QIL
Sbjct: 225 DLKETYRCIK-QVHYTLPASLSLPARQLLAAILRASPRDRPSIDQIL 270
>BC032784-1|AAH32784.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II delta protein.
Length = 478
Score = 117 bits (281), Expect = 6e-26
Identities = 79/242 (32%), Positives = 126/242 (52%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLS 474
L + I ++ E +Q++E+V++CH G+VHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAK-RITASEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WI 272
>BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 117 bits (281), Expect = 6e-26
Identities = 65/227 (28%), Positives = 121/227 (53%), Gaps = 1/227 (0%)
Frame = -3
Query: 815 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 636
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 89 AVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 148
Query: 635 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 456
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 207
Query: 455 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDT 276
++P +T CG+ Y +PE+L + P ++DVWS+G V+Y ++ G PF+
Sbjct: 208 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLGCVMYTLLCGSPPFETA 263
Query: 275 NYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQIL 138
+ + + ++ +V + +S R+L+ IL A + R I QIL
Sbjct: 264 DLKETYRCIK-QVHYTLPASLSLPARQLLAAILRASPRDRPSIDQIL 309
>AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 117 bits (281), Expect = 6e-26
Identities = 65/227 (28%), Positives = 121/227 (53%), Gaps = 1/227 (0%)
Frame = -3
Query: 815 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 636
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 89 AVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 148
Query: 635 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 456
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 207
Query: 455 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDT 276
++P +T CG+ Y +PE+L + P ++DVWS+G V+Y ++ G PF+
Sbjct: 208 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLGCVMYTLLCGSPPFETA 263
Query: 275 NYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQIL 138
+ + + ++ +V + +S R+L+ IL A + R I QIL
Sbjct: 264 DLKETYRCIK-QVHYTLPASLSLPARQLLAAILRASPRDRPSIDQIL 309
>AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 117 bits (281), Expect = 6e-26
Identities = 65/227 (28%), Positives = 121/227 (53%), Gaps = 1/227 (0%)
Frame = -3
Query: 815 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 636
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 89 AVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 148
Query: 635 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 456
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 207
Query: 455 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDT 276
++P +T CG+ Y +PE+L + P ++DVWS+G V+Y ++ G PF+
Sbjct: 208 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLGCVMYTLLCGSPPFETA 263
Query: 275 NYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQIL 138
+ + + ++ +V + +S R+L+ IL A + R I QIL
Sbjct: 264 DLKETYRCIK-QVHYTLPASLSLPARQLLAAILRASPRDRPSIDQIL 309
>AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 variant
protein.
Length = 621
Score = 117 bits (281), Expect = 6e-26
Identities = 65/227 (28%), Positives = 121/227 (53%), Gaps = 1/227 (0%)
Frame = -3
Query: 815 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 636
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 64 AVKVIPQSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 123
Query: 635 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 456
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 124 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 182
Query: 455 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDT 276
++P +T CG+ Y +PE+L + P ++DVWS+G V+Y ++ G PF+
Sbjct: 183 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLGCVMYTLLCGSPPFETA 238
Query: 275 NYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQIL 138
+ + + ++ +V + +S R+L+ IL A + R I QIL
Sbjct: 239 DLKETYRCIK-QVHYTLPASLSLPARQLLAAILRASPRDRPSIDQIL 284
>AB209288-1|BAD92525.1| 522|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
isoform 1 variant protein.
Length = 522
Score = 117 bits (281), Expect = 6e-26
Identities = 79/242 (32%), Positives = 126/242 (52%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 69 EYAAKIINTKKLSARDHQK--LEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG 126
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLS 474
L + I ++ E +Q++E+V++CH G+VHRD+K ENLL+ G +KL+
Sbjct: 127 ELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLA 186
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G
Sbjct: 187 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGY 241
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 242 PPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAK-RITASEALKHP 300
Query: 128 WL 123
W+
Sbjct: 301 WI 302
>AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine
protein kinase protein.
Length = 646
Score = 116 bits (280), Expect = 8e-26
Identities = 65/227 (28%), Positives = 121/227 (53%), Gaps = 1/227 (0%)
Frame = -3
Query: 815 AIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLL 636
A+K+I + + + ++ + EIE+ + L+H +++RF E +YI +E SL
Sbjct: 89 AVKVIPQSRVVKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADNIYIFLELCSRKSLA 148
Query: 635 DIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFAR 456
I + + E R + +Q++ + Y H+RG++HRD+K N + + +K+ DFG A
Sbjct: 149 HIWKARHTLLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLA- 207
Query: 455 GHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDT 276
++P +T CG+ Y +PE+L + P ++DVWS+G V+Y ++ G PF+
Sbjct: 208 ARLEPPE---QRKKTICGTPNYVAPEVLLRQGHGP-EADVWSLGCVMYTLLCGSPPFETA 263
Query: 275 NYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQIL 138
+ + + ++ +V + +S R+L+ IL A + R I QIL
Sbjct: 264 DLKETYRCIK-QVHYTLPASLSLPARQLLAAILRASPRDRPSIDQIL 309
>AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional
calcium/calmodulin-dependent protein kinase II delta2
isoform protein.
Length = 499
Score = 116 bits (280), Expect = 8e-26
Identities = 79/240 (32%), Positives = 125/240 (52%), Gaps = 9/240 (3%)
Frame = -3
Query: 815 AIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSL 639
A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G L
Sbjct: 41 AAKIINTKKLSARDHQK--LEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGEL 98
Query: 638 LDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDF 468
+ I ++ E +Q++E+V++CH G+VHRD+K ENLL+ G +KL+DF
Sbjct: 99 FEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADF 158
Query: 467 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 288
G A + F F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G P
Sbjct: 159 GLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPP 213
Query: 287 FDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 123
F D + +L +Q++ FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 214 FWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAK-RITASEALKHPWI 272
>U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein
kinase protein.
Length = 458
Score = 116 bits (279), Expect = 1e-25
Identities = 70/212 (33%), Positives = 113/212 (53%), Gaps = 2/212 (0%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 576
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 187 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 246
Query: 575 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 396
LV AV Y + ++HRD K EN+++ IKL DFG A + K L TFCG+
Sbjct: 247 LVSAVGYLRLKDIIHRDFKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 301
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 216
Y +PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P
Sbjct: 302 EYCAPEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--L 354
Query: 215 VSAECRKLITRILAPL-KMRVKIPQILADPWL 123
VS E L++ +L P+ + R + +++ DPW+
Sbjct: 355 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 386
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 116 bits (279), Expect = 1e-25
Identities = 78/255 (30%), Positives = 126/255 (49%), Gaps = 7/255 (2%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A R VAIK I+K G + + EI V+ +KH N++ E+
Sbjct: 30 AFSEVILAEDKRTQKLVAIKCIAKEALEGK--EGSMENEIAVLHKIKHPNIVALDDIYES 87
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y++M+ G L D I + E R Q+++AV Y H+ G+VHRD+K ENL
Sbjct: 88 GGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENL 147
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L +D I +SDFG ++ M+ V + T CG+ Y +PE+L PY + D
Sbjct: 148 LYYSLDEDSKIMISDFGLSK--MEDPGSVLS---TACGTPGYVAPEVLAQKPY-SKAVDC 201
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRIL-APL 168
WS+GV+ Y ++ G PF D N +L +Q+ + + P +S + I ++
Sbjct: 202 WSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDP 261
Query: 167 KMRVKIPQILADPWL 123
+ R Q L PW+
Sbjct: 262 EKRFTCEQALQHPWI 276
>BC106755-1|AAI06756.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 116 bits (279), Expect = 1e-25
Identities = 78/255 (30%), Positives = 126/255 (49%), Gaps = 7/255 (2%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A R VAIK I+K G + + EI V+ +KH N++ E+
Sbjct: 30 AFSEVILAEDKRTQKLVAIKCIAKEALEGK--EGSMENEIAVLHKIKHPNIVALDDIYES 87
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y++M+ G L D I + E R Q+++AV Y H+ G+VHRD+K ENL
Sbjct: 88 GGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENL 147
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L +D I +SDFG ++ M+ V + T CG+ Y +PE+L PY + D
Sbjct: 148 LYYSLDEDSKIMISDFGLSK--MEDPGSVLS---TACGTPGYVAPEVLAQKPY-SKAVDC 201
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRIL-APL 168
WS+GV+ Y ++ G PF D N +L +Q+ + + P +S + I ++
Sbjct: 202 WSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDP 261
Query: 167 KMRVKIPQILADPWL 123
+ R Q L PW+
Sbjct: 262 EKRFTCEQALQHPWI 276
>BC106754-1|AAI06755.1| 370|Homo sapiens
calcium/calmodulin-dependent protein kinase I protein.
Length = 370
Score = 116 bits (279), Expect = 1e-25
Identities = 78/255 (30%), Positives = 126/255 (49%), Gaps = 7/255 (2%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A R VAIK I+K G + + EI V+ +KH N++ E+
Sbjct: 30 AFSEVILAEDKRTQKLVAIKCIAKEALEGK--EGSMENEIAVLHKIKHPNIVALDDIYES 87
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y++M+ G L D I + E R Q+++AV Y H+ G+VHRD+K ENL
Sbjct: 88 GGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENL 147
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L +D I +SDFG ++ M+ V + T CG+ Y +PE+L PY + D
Sbjct: 148 LYYSLDEDSKIMISDFGLSK--MEDPGSVLS---TACGTPGYVAPEVLAQKPY-SKAVDC 201
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRIL-APL 168
WS+GV+ Y ++ G PF D N +L +Q+ + + P +S + I ++
Sbjct: 202 WSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDP 261
Query: 167 KMRVKIPQILADPWL 123
+ R Q L PW+
Sbjct: 262 EKRFTCEQALQHPWI 276
>AY987011-1|AAX88806.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
protein.
Length = 489
Score = 116 bits (279), Expect = 1e-25
Identities = 79/241 (32%), Positives = 125/241 (51%), Gaps = 9/241 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLS 474
L + I ++ E +Q++E+V++CH G+VHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAK-RITASEALKHP 270
Query: 128 W 126
W
Sbjct: 271 W 271
>AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein.
Length = 608
Score = 116 bits (279), Expect = 1e-25
Identities = 77/258 (29%), Positives = 129/258 (50%), Gaps = 10/258 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK A+KII K + G + + EI +++ L H N+++ + ET
Sbjct: 326 NFAVVKECRHRETRQAYAMKIIDKSRLKGK--EDMVDSEILIIQSLSHPNIVKLHEVYET 383
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+Y+++EY + G L D I + E L +A+ + H++ +VHRD+K ENL
Sbjct: 384 DMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENL 443
Query: 506 LM----DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSD 339
L+ D +KL+DFG A+ ++P +F T CG+ Y +PEIL Y + D
Sbjct: 444 LVQRNEDKSTTLKLADFGLAKHVVRP---IF----TVCGTPTYVAPEILSEKGY-GLEVD 495
Query: 338 VWSMGVVLYAIVYGRLPF--DDTNYTQLLKQVQ-NKVSF--PREPKVSAECRKLITRIL- 177
+W+ GV+LY ++ G PF + + +L +Q F P +S + L++R+L
Sbjct: 496 MWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAKDLVSRLLV 555
Query: 176 APLKMRVKIPQILADPWL 123
K R Q+L PW+
Sbjct: 556 VDPKKRYTAHQVLQHPWI 573
>X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B
protein.
Length = 417
Score = 116 bits (278), Expect = 1e-25
Identities = 67/194 (34%), Positives = 114/194 (58%), Gaps = 2/194 (1%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 573
E V + +H L R + +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 135 ENRVQQNSRHPFLTRLKYSFQTHDRLCFVMEYANGGELFFHLSRERVFAEDRARFYGAEI 194
Query: 572 VEAVDYCH-ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 396
V A+DY H E+ VV+RD+K ENL++D +IK++DFG + + K+G A +TFCG+
Sbjct: 195 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTP 250
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 219
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 251 EYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-- 307
Query: 218 KVSAECRKLITRIL 177
+ E + L++ +L
Sbjct: 308 TLGPEAKSLLSGLL 321
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 116 bits (278), Expect = 1e-25
Identities = 59/167 (35%), Positives = 100/167 (59%), Gaps = 1/167 (0%)
Frame = -3
Query: 725 HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHE 546
H L + +T R++ VME+ G L+ I+K + DE R R + +++ A+ + H+
Sbjct: 412 HPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHD 471
Query: 545 RGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKG 366
+G+++RD+K +N+L+DH + KL+DFG + + NGV + TFCG+ Y +PEIL+
Sbjct: 472 KGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI--CNGV--TTATFCGTPDYIAPEILQE 527
Query: 365 VPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 228
+ Y P D W+MGV+LY ++ G PF+ N L + + N +V +P
Sbjct: 528 MLYGPA-VDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYP 573
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 116 bits (278), Expect = 1e-25
Identities = 59/167 (35%), Positives = 100/167 (59%), Gaps = 1/167 (0%)
Frame = -3
Query: 725 HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHE 546
H L + +T R++ VME+ G L+ I+K + DE R R + +++ A+ + H+
Sbjct: 413 HPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHD 472
Query: 545 RGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKG 366
+G+++RD+K +N+L+DH + KL+DFG + + NGV + TFCG+ Y +PEIL+
Sbjct: 473 KGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI--CNGV--TTATFCGTPDYIAPEILQE 528
Query: 365 VPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 228
+ Y P D W+MGV+LY ++ G PF+ N L + + N +V +P
Sbjct: 529 MLYGPA-VDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYP 574
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase RLPK
protein.
Length = 802
Score = 116 bits (278), Expect = 1e-25
Identities = 86/269 (31%), Positives = 139/269 (51%), Gaps = 16/269 (5%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLK-HENLIRFLQAIE 690
S++ + + N A+KIISK ++ +EI +K + H N+++ +
Sbjct: 436 SFSICRKCVHKKSNQAFAVKIISK------RMEANTQKEITALKLCEGHPNIVKLHEVFH 489
Query: 689 TTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
++VME G L + I+K +H ET ++LV AV + H+ GVVHRD+K EN
Sbjct: 490 DQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPEN 549
Query: 509 LLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSD 339
LL + L IK+ DFGFAR +KP + +T C + YA+PE+L Y + D
Sbjct: 550 LLFTDENDNLEIKIIDFGFAR--LKPPDN--QPLKTPCFTLHYAAPELLNQNGY-DESCD 604
Query: 338 VWSMGVVLYAIVYGRLPFDD-------TNYTQLLKQV-QNKVSFPRE--PKVSAECRKLI 189
+WS+GV+LY ++ G++PF T+ +++K++ + SF E VS E + LI
Sbjct: 605 LWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLI 664
Query: 188 TRILA--PLKMRVKIPQILADPWLNPNQQ 108
+L P K R+K+ + + WL Q
Sbjct: 665 QGLLTVDPNK-RLKMSGLRYNEWLQDGSQ 692
Score = 87.8 bits (208), Expect = 4e-17
Identities = 48/184 (26%), Positives = 101/184 (54%), Gaps = 4/184 (2%)
Frame = -3
Query: 716 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 537
L+ A +T +++++++Y G L + + + E + + ++V A+++ H+ G+
Sbjct: 114 LVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGI 173
Query: 536 VHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPY 357
++RDIK EN+L+D ++ L+DFG ++ + + + +FCG+ Y +P+I++G
Sbjct: 174 IYRDIKLENILLDSNGHVVLTDFGLSKEFVADET---ERAYSFCGTIEYMAPDIVRGGDS 230
Query: 356 -RPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKV--SFPREP-KVSAECRKLI 189
+ D WS+GV++Y ++ G PF ++ ++ S P P ++SA + LI
Sbjct: 231 GHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLI 290
Query: 188 TRIL 177
R+L
Sbjct: 291 QRLL 294
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 116 bits (278), Expect = 1e-25
Identities = 86/269 (31%), Positives = 139/269 (51%), Gaps = 16/269 (5%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLK-HENLIRFLQAIE 690
S++ + + N A+KIISK ++ +EI +K + H N+++ +
Sbjct: 436 SFSICRKCVHKKSNQAFAVKIISK------RMEANTQKEITALKLCEGHPNIVKLHEVFH 489
Query: 689 TTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCEN 510
++VME G L + I+K +H ET ++LV AV + H+ GVVHRD+K EN
Sbjct: 490 DQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPEN 549
Query: 509 LLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSD 339
LL + L IK+ DFGFAR +KP + +T C + YA+PE+L Y + D
Sbjct: 550 LLFTDENDNLEIKIIDFGFAR--LKPPDN--QPLKTPCFTLHYAAPELLNQNGY-DESCD 604
Query: 338 VWSMGVVLYAIVYGRLPFDD-------TNYTQLLKQV-QNKVSFPRE--PKVSAECRKLI 189
+WS+GV+LY ++ G++PF T+ +++K++ + SF E VS E + LI
Sbjct: 605 LWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLI 664
Query: 188 TRILA--PLKMRVKIPQILADPWLNPNQQ 108
+L P K R+K+ + + WL Q
Sbjct: 665 QGLLTVDPNK-RLKMSGLRYNEWLQDGSQ 692
Score = 87.8 bits (208), Expect = 4e-17
Identities = 48/184 (26%), Positives = 101/184 (54%), Gaps = 4/184 (2%)
Frame = -3
Query: 716 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 537
L+ A +T +++++++Y G L + + + E + + ++V A+++ H+ G+
Sbjct: 114 LVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGI 173
Query: 536 VHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPY 357
++RDIK EN+L+D ++ L+DFG ++ + + + +FCG+ Y +P+I++G
Sbjct: 174 IYRDIKLENILLDSNGHVVLTDFGLSKEFVADET---ERAYSFCGTIEYMAPDIVRGGDS 230
Query: 356 -RPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKV--SFPREP-KVSAECRKLI 189
+ D WS+GV++Y ++ G PF ++ ++ S P P ++SA + LI
Sbjct: 231 GHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLI 290
Query: 188 TRIL 177
R+L
Sbjct: 291 QRLL 294
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 115 bits (277), Expect = 2e-25
Identities = 66/194 (34%), Positives = 114/194 (58%), Gaps = 2/194 (1%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 573
E V++ +H L + +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
Query: 572 VEAVDYCH-ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 396
V A+DY H E+ VV+RD+K ENL++D +IK++DFG + + K+G A +TFCG+
Sbjct: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTP 313
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 219
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 314 EYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-- 370
Query: 218 KVSAECRKLITRIL 177
+ E + L++ +L
Sbjct: 371 TLGPEAKSLLSGLL 384
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 115 bits (277), Expect = 2e-25
Identities = 66/194 (34%), Positives = 114/194 (58%), Gaps = 2/194 (1%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 573
E V++ +H L + +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
Query: 572 VEAVDYCH-ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 396
V A+DY H E+ VV+RD+K ENL++D +IK++DFG + + K+G A +TFCG+
Sbjct: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTP 313
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 219
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 314 EYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-- 370
Query: 218 KVSAECRKLITRIL 177
+ E + L++ +L
Sbjct: 371 TLGPEAKSLLSGLL 384
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 115 bits (277), Expect = 2e-25
Identities = 66/194 (34%), Positives = 114/194 (58%), Gaps = 2/194 (1%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 573
E V++ +H L + +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
Query: 572 VEAVDYCH-ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 396
V A+DY H E+ VV+RD+K ENL++D +IK++DFG + + K+G A +TFCG+
Sbjct: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTP 313
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 219
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 314 EYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-- 370
Query: 218 KVSAECRKLITRIL 177
+ E + L++ +L
Sbjct: 371 TLGPEAKSLLSGLL 384
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 115 bits (277), Expect = 2e-25
Identities = 66/194 (34%), Positives = 114/194 (58%), Gaps = 2/194 (1%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 573
E V++ +H L + +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
Query: 572 VEAVDYCH-ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 396
V A+DY H E+ VV+RD+K ENL++D +IK++DFG + + K+G A +TFCG+
Sbjct: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTP 313
Query: 395 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 219
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 314 EYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-- 370
Query: 218 KVSAECRKLITRIL 177
+ E + L++ +L
Sbjct: 371 TLGPEAKSLLSGLL 384
>U23460-1|AAC99802.1| 664|Homo sapiens proline rich
calmodulin-dependent protein kinase protein.
Length = 664
Score = 115 bits (276), Expect = 3e-25
Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WV 272
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 115 bits (276), Expect = 3e-25
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 8/256 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A A+K I K G + + EI V++ +KHEN++ E+
Sbjct: 33 AFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYES 90
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+K ENL
Sbjct: 91 PNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L D I +SDFG ++ M+ K V + T CG+ Y +PE+L PY + D
Sbjct: 151 LYYSQDEESKIMISDFGLSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDC 204
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRILA--P 171
WS+GV+ Y ++ G PF D N ++L +Q+ + + P +S + I ++ P
Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query: 170 LKMRVKIPQILADPWL 123
K R Q PW+
Sbjct: 265 NK-RYTCEQAARHPWI 279
>BC019070-1|AAH19070.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II beta protein.
Length = 503
Score = 115 bits (276), Expect = 3e-25
Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WV 272
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 115 bits (276), Expect = 3e-25
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 8/256 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A A+K I K G + + EI V++ +KHEN++ E+
Sbjct: 33 AFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYES 90
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+K ENL
Sbjct: 91 PNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L D I +SDFG ++ M+ K V + T CG+ Y +PE+L PY + D
Sbjct: 151 LYYSQDEESKIMISDFGLSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDC 204
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRILA--P 171
WS+GV+ Y ++ G PF D N ++L +Q+ + + P +S + I ++ P
Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query: 170 LKMRVKIPQILADPWL 123
K R Q PW+
Sbjct: 265 NK-RYTCEQAARHPWI 279
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 115 bits (276), Expect = 3e-25
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 8/256 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A A+K I K G + + EI V++ +KHEN++ E+
Sbjct: 33 AFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYES 90
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+K ENL
Sbjct: 91 PNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L D I +SDFG ++ M+ K V + T CG+ Y +PE+L PY + D
Sbjct: 151 LYYSQDEESKIMISDFGLSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDC 204
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRILA--P 171
WS+GV+ Y ++ G PF D N ++L +Q+ + + P +S + I ++ P
Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query: 170 LKMRVKIPQILADPWL 123
K R Q PW+
Sbjct: 265 NK-RYTCEQAARHPWI 279
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 115 bits (276), Expect = 3e-25
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 8/256 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A A+K I K G + + EI V++ +KHEN++ E+
Sbjct: 33 AFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYES 90
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+K ENL
Sbjct: 91 PNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L D I +SDFG ++ M+ K V + T CG+ Y +PE+L PY + D
Sbjct: 151 LYYSQDEESKIMISDFGLSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDC 204
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRILA--P 171
WS+GV+ Y ++ G PF D N ++L +Q+ + + P +S + I ++ P
Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query: 170 LKMRVKIPQILADPWL 123
K R Q PW+
Sbjct: 265 NK-RYTCEQAARHPWI 279
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 115 bits (276), Expect = 3e-25
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 8/256 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A A+K I K G + + EI V++ +KHEN++ E+
Sbjct: 33 AFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYES 90
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+K ENL
Sbjct: 91 PNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L D I +SDFG ++ M+ K V + T CG+ Y +PE+L PY + D
Sbjct: 151 LYYSQDEESKIMISDFGLSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDC 204
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRILA--P 171
WS+GV+ Y ++ G PF D N ++L +Q+ + + P +S + I ++ P
Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query: 170 LKMRVKIPQILADPWL 123
K R Q PW+
Sbjct: 265 NK-RYTCEQAARHPWI 279
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 115 bits (276), Expect = 3e-25
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 8/256 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A A+K I K G + + EI V++ +KHEN++ E+
Sbjct: 33 AFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYES 90
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+K ENL
Sbjct: 91 PNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L D I +SDFG ++ M+ K V + T CG+ Y +PE+L PY + D
Sbjct: 151 LYYSQDEESKIMISDFGLSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDC 204
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRILA--P 171
WS+GV+ Y ++ G PF D N ++L +Q+ + + P +S + I ++ P
Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query: 170 LKMRVKIPQILADPWL 123
K R Q PW+
Sbjct: 265 NK-RYTCEQAARHPWI 279
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 115 bits (276), Expect = 3e-25
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 8/256 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A A+K I K G + + EI V++ +KHEN++ E+
Sbjct: 33 AFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYES 90
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+K ENL
Sbjct: 91 PNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L D I +SDFG ++ M+ K V + T CG+ Y +PE+L PY + D
Sbjct: 151 LYYSQDEESKIMISDFGLSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDC 204
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRILA--P 171
WS+GV+ Y ++ G PF D N ++L +Q+ + + P +S + I ++ P
Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query: 170 LKMRVKIPQILADPWL 123
K R Q PW+
Sbjct: 265 NK-RYTCEQAARHPWI 279
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 115 bits (276), Expect = 3e-25
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 8/256 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A A+K I K G + + EI V++ +KHEN++ E+
Sbjct: 33 AFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYES 90
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+K ENL
Sbjct: 91 PNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L D I +SDFG ++ M+ K V + T CG+ Y +PE+L PY + D
Sbjct: 151 LYYSQDEESKIMISDFGLSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDC 204
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRILA--P 171
WS+GV+ Y ++ G PF D N ++L +Q+ + + P +S + I ++ P
Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query: 170 LKMRVKIPQILADPWL 123
K R Q PW+
Sbjct: 265 NK-RYTCEQAARHPWI 279
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 115 bits (276), Expect = 3e-25
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 8/256 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A A+K I K G + + EI V++ +KHEN++ E+
Sbjct: 33 AFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYES 90
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+K ENL
Sbjct: 91 PNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L D I +SDFG ++ M+ K V + T CG+ Y +PE+L PY + D
Sbjct: 151 LYYSQDEESKIMISDFGLSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDC 204
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRILA--P 171
WS+GV+ Y ++ G PF D N ++L +Q+ + + P +S + I ++ P
Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query: 170 LKMRVKIPQILADPWL 123
K R Q PW+
Sbjct: 265 NK-RYTCEQAARHPWI 279
>AK222703-1|BAD96423.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase IIB isoform
2 variant protein.
Length = 542
Score = 115 bits (276), Expect = 3e-25
Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WV 272
>AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 4 protein.
Length = 518
Score = 115 bits (276), Expect = 3e-25
Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WV 272
>AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 2 protein.
Length = 479
Score = 115 bits (276), Expect = 3e-25
Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WV 272
>AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 1 protein.
Length = 503
Score = 115 bits (276), Expect = 3e-25
Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WV 272
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 115 bits (276), Expect = 3e-25
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 8/256 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A A+K I K G + + EI V++ +KHEN++ E+
Sbjct: 33 AFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYES 90
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+K ENL
Sbjct: 91 PNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L D I +SDFG ++ M+ K V + T CG+ Y +PE+L PY + D
Sbjct: 151 LYYSQDEESKIMISDFGLSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDC 204
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRILA--P 171
WS+GV+ Y ++ G PF D N ++L +Q+ + + P +S + I ++ P
Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query: 170 LKMRVKIPQILADPWL 123
K R Q PW+
Sbjct: 265 NK-RYTCEQAARHPWI 279
>AF140350-1|AAD42070.1| 449|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 7
subunit protein.
Length = 449
Score = 115 bits (276), Expect = 3e-25
Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WV 272
>AF083419-1|AAD42038.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e
subunit protein.
Length = 517
Score = 115 bits (276), Expect = 3e-25
Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WV 272
>AF081924-1|AAD42037.1| 492|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 6
subunit protein.
Length = 492
Score = 115 bits (276), Expect = 3e-25
Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WV 272
>AF081572-1|AAD42036.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e'
subunit protein.
Length = 503
Score = 115 bits (276), Expect = 3e-25
Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WV 272
>AF078803-1|AAD42035.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 115 bits (276), Expect = 3e-25
Identities = 80/242 (33%), Positives = 125/242 (51%), Gaps = 9/242 (3%)
Frame = -3
Query: 821 QVAIKIIS-KFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 645
+ A KII+ K + D+ K L RE + + LKH N++R +I Y+V + G
Sbjct: 39 EYAAKIINTKKLSARDHQK--LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGG 96
Query: 644 SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLS 474
L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+
Sbjct: 97 ELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLA 156
Query: 473 DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGR 294
DFG A + F F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G
Sbjct: 157 DFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGY 211
Query: 293 LPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADP 129
PF D + +L +Q++ FP V+ E + LI ++L P K R+ + L P
Sbjct: 212 PPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHP 270
Query: 128 WL 123
W+
Sbjct: 271 WV 272
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 115 bits (276), Expect = 3e-25
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 8/256 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
+++ V +A A+K I K G + + EI V++ +KHEN++ E+
Sbjct: 33 AFSEVVLAEEKATGKLFAVKCIPKKALKGK--ESSIENEIAVLRKIKHENIVALEDIYES 90
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+ +Y+VM+ G L D I + E +Q+++AV Y H G+VHRD+K ENL
Sbjct: 91 PNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENL 150
Query: 506 L---MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 336
L D I +SDFG ++ M+ K V + T CG+ Y +PE+L PY + D
Sbjct: 151 LYYSQDEESKIMISDFGLSK--MEGKGDVMS---TACGTPGYVAPEVLAQKPY-SKAVDC 204
Query: 335 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRILA--P 171
WS+GV+ Y ++ G PF D N ++L +Q+ + + P +S + I ++ P
Sbjct: 205 WSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDP 264
Query: 170 LKMRVKIPQILADPWL 123
K R Q PW+
Sbjct: 265 NK-RYTCEQAARHPWI 279
>BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2
(Drosophila) protein.
Length = 685
Score = 114 bits (274), Expect = 5e-25
Identities = 60/219 (27%), Positives = 119/219 (54%)
Frame = -3
Query: 830 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAE 651
+N A KII + + ++ + +EIE+ + L H+++++F E +YI++EY
Sbjct: 104 NNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCS 163
Query: 650 NGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSD 471
S+ I++ + + E R + +Q+V + Y HE+ ++HRD+K N ++ + +K+ D
Sbjct: 164 RRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGD 223
Query: 470 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 291
FG A ++P + T CG+ Y SPE+L + +SD+W++G V+Y ++ GR
Sbjct: 224 FGLA-ARLEP---LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALGCVMYTMLLGRP 278
Query: 290 PFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA 174
PF+ TN + + ++ + + + A + LI +L+
Sbjct: 279 PFETTNLKETYRCIR-EARYTMPSSLLAPAKHLIASMLS 316
>AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein
protein.
Length = 716
Score = 114 bits (274), Expect = 5e-25
Identities = 79/267 (29%), Positives = 131/267 (49%), Gaps = 10/267 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK + A+KII K + G + + E+ +++ +KH N+I ++ +ET
Sbjct: 354 NFAVVKECIDRSTGKEFALKIIDKAKCCGK--EHLIENEVSILRRVKHPNIIMLVEEMET 411
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+++VME + G L D I E G L A+ Y H +VHRDIK ENL
Sbjct: 412 ATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENL 471
Query: 506 LM----DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSD 339
L+ D ++KL DFG A P T CG+ Y +PEI+ Y + D
Sbjct: 472 LVCEYPDGTKSLKLGDFGLATVVEGP-------LYTVCGTPTYVAPEIIAETGYGLK-VD 523
Query: 338 VWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQV-QNKVSFPRE--PKVSAECRKLITRIL- 177
+W+ GV+ Y ++ G PF N Q L Q+ K+ FP ++ ++LI+++L
Sbjct: 524 IWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQ 583
Query: 176 APLKMRVKIPQILADPWLNPNQQSKHD 96
++ R QIL+ PW++ + +++
Sbjct: 584 VNVEARCTAGQILSHPWVSDDASQENN 610
>AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens
cDNA FLJ40844 fis, clone TRACH2014356, highly similar to
SERINE/THREONINE-PROTEIN KINASE SNK (EC 2.7.1.-). ).
Length = 372
Score = 114 bits (274), Expect = 5e-25
Identities = 60/219 (27%), Positives = 119/219 (54%)
Frame = -3
Query: 830 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAE 651
+N A KII + + ++ + +EIE+ + L H+++++F E +YI++EY
Sbjct: 97 NNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCS 156
Query: 650 NGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSD 471
S+ I++ + + E R + +Q+V + Y HE+ ++HRD+K N ++ + +K+ D
Sbjct: 157 RRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGD 216
Query: 470 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 291
FG A ++P + T CG+ Y SPE+L + +SD+W++G V+Y ++ GR
Sbjct: 217 FGLA-ARLEP---LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALGCVMYTMLLGRP 271
Query: 290 PFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA 174
PF+ TN + + ++ + + + A + LI +L+
Sbjct: 272 PFETTNLKETYRCIR-EARYTMPSSLLAPAKHLIASMLS 309
>AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 114 bits (274), Expect = 5e-25
Identities = 60/219 (27%), Positives = 119/219 (54%)
Frame = -3
Query: 830 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAE 651
+N A KII + + ++ + +EIE+ + L H+++++F E +YI++EY
Sbjct: 104 NNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCS 163
Query: 650 NGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSD 471
S+ I++ + + E R + +Q+V + Y HE+ ++HRD+K N ++ + +K+ D
Sbjct: 164 RRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGD 223
Query: 470 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 291
FG A ++P + T CG+ Y SPE+L + +SD+W++G V+Y ++ GR
Sbjct: 224 FGLA-ARLEP---LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALGCVMYTMLLGRP 278
Query: 290 PFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA 174
PF+ TN + + ++ + + + A + LI +L+
Sbjct: 279 PFETTNLKETYRCIR-EARYTMPSSLLAPAKHLIASMLS 316
>AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 114 bits (274), Expect = 5e-25
Identities = 60/219 (27%), Positives = 119/219 (54%)
Frame = -3
Query: 830 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAE 651
+N A KII + + ++ + +EIE+ + L H+++++F E +YI++EY
Sbjct: 104 NNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCS 163
Query: 650 NGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSD 471
S+ I++ + + E R + +Q+V + Y HE+ ++HRD+K N ++ + +K+ D
Sbjct: 164 RRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGD 223
Query: 470 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 291
FG A ++P + T CG+ Y SPE+L + +SD+W++G V+Y ++ GR
Sbjct: 224 FGLA-ARLEP---LEHRRRTICGTPNYLSPEVLNKQGH-GCESDIWALGCVMYTMLLGRP 278
Query: 290 PFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA 174
PF+ TN + + ++ + + + A + LI +L+
Sbjct: 279 PFETTNLKETYRCIR-EARYTMPSSLLAPAKHLIASMLS 316
>AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein.
Length = 443
Score = 114 bits (274), Expect = 5e-25
Identities = 79/267 (29%), Positives = 131/267 (49%), Gaps = 10/267 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK + A+KII K + G + + E+ +++ +KH N+I ++ +ET
Sbjct: 151 NFAVVKECIDRSTGKEFALKIIDKAKCCGK--EHLIENEVSILRRVKHPNIIMLVEEMET 208
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+++VME + G L D I E G L A+ Y H +VHRDIK ENL
Sbjct: 209 ATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENL 268
Query: 506 LM----DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSD 339
L+ D ++KL DFG A P T CG+ Y +PEI+ Y + D
Sbjct: 269 LVCEYPDGTKSLKLGDFGLATVVEGP-------LYTVCGTPTYVAPEIIAETGYGLK-VD 320
Query: 338 VWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQV-QNKVSFPRE--PKVSAECRKLITRIL- 177
+W+ GV+ Y ++ G PF N Q L Q+ K+ FP ++ ++LI+++L
Sbjct: 321 IWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQ 380
Query: 176 APLKMRVKIPQILADPWLNPNQQSKHD 96
++ R QIL+ PW++ + +++
Sbjct: 381 VNVEARCTAGQILSHPWVSDDASQENN 407
>AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein
DKFZp761I032 variant protein.
Length = 796
Score = 114 bits (274), Expect = 5e-25
Identities = 79/267 (29%), Positives = 131/267 (49%), Gaps = 10/267 (3%)
Frame = -3
Query: 866 SYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIET 687
++A VK + A+KII K + G + + E+ +++ +KH N+I ++ +ET
Sbjct: 434 NFAVVKECIDRSTGKEFALKIIDKAKCCGK--EHLIENEVSILRRVKHPNIIMLVEEMET 491
Query: 686 THRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 507
+++VME + G L D I E G L A+ Y H +VHRDIK ENL
Sbjct: 492 ATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHGLSIVHRDIKPENL 551
Query: 506 LM----DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSD 339
L+ D ++KL DFG A P T CG+ Y +PEI+ Y + D
Sbjct: 552 LVCEYPDGTKSLKLGDFGLATVVEGP-------LYTVCGTPTYVAPEIIAETGYGLK-VD 603
Query: 338 VWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQV-QNKVSFPRE--PKVSAECRKLITRIL- 177
+W+ GV+ Y ++ G PF N Q L Q+ K+ FP ++ ++LI+++L
Sbjct: 604 IWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEFPAPYWDNITDSAKELISQMLQ 663
Query: 176 APLKMRVKIPQILADPWLNPNQQSKHD 96
++ R QIL+ PW++ + +++
Sbjct: 664 VNVEARCTAGQILSHPWVSDDASQENN 690
>Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein.
Length = 445
Score = 113 bits (273), Expect = 6e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -3
Query: 770 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 609
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 608 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 444
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 443 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 264
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 263 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 93
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 92 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 3
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase 1
protein.
Length = 445
Score = 113 bits (273), Expect = 6e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -3
Query: 770 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 609
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 608 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 444
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 443 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 264
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 263 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 93
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 92 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 3
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin dependent
protein kinase protein.
Length = 473
Score = 113 bits (273), Expect = 6e-25
Identities = 75/224 (33%), Positives = 119/224 (53%), Gaps = 8/224 (3%)
Frame = -3
Query: 770 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 591
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 590 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 420
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 419 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ-LLKQVQN 243
+T CG+ Y +PEIL+G Y P + D+WS+G++ Y ++ G PF D Q + +++ N
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILN 256
Query: 242 KVSF---PREPKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 123
+ P +VS + L+ + I+ K R+ Q L PW+
Sbjct: 257 CEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-dependent
protein kinase protein.
Length = 473
Score = 113 bits (273), Expect = 6e-25
Identities = 75/224 (33%), Positives = 119/224 (53%), Gaps = 8/224 (3%)
Frame = -3
Query: 770 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 591
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 590 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 420
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 419 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ-LLKQVQN 243
+T CG+ Y +PEIL+G Y P + D+WS+G++ Y ++ G PF D Q + +++ N
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILN 256
Query: 242 KVSF---PREPKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 123
+ P +VS + L+ + I+ K R+ Q L PW+
Sbjct: 257 CEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent protein
kinase IV protein.
Length = 473
Score = 113 bits (273), Expect = 6e-25
Identities = 75/224 (33%), Positives = 119/224 (53%), Gaps = 8/224 (3%)
Frame = -3
Query: 770 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 591
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 590 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 420
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 419 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ-LLKQVQN 243
+T CG+ Y +PEIL+G Y P + D+WS+G++ Y ++ G PF D Q + +++ N
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILN 256
Query: 242 KVSF---PREPKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 123
+ P +VS + L+ + I+ K R+ Q L PW+
Sbjct: 257 CEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 113 bits (273), Expect = 6e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -3
Query: 770 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 609
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 608 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 444
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 443 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 264
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 263 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 93
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 92 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 3
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein.
Length = 326
Score = 113 bits (273), Expect = 6e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -3
Query: 770 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 609
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 608 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 444
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 443 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 264
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 263 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 93
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 92 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 3
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 113 bits (273), Expect = 6e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -3
Query: 770 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 609
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 608 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 444
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 443 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 264
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 263 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 93
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 92 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 3
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>BC025687-1|AAH25687.1| 473|Homo sapiens
calcium/calmodulin-dependent protein kinase IV protein.
Length = 473
Score = 113 bits (273), Expect = 6e-25
Identities = 75/224 (33%), Positives = 119/224 (53%), Gaps = 8/224 (3%)
Frame = -3
Query: 770 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 591
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 590 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 420
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 419 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ-LLKQVQN 243
+T CG+ Y +PEIL+G Y P + D+WS+G++ Y ++ G PF D Q + +++ N
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILN 256
Query: 242 KVSF---PREPKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 123
+ P +VS + L+ + I+ K R+ Q L PW+
Sbjct: 257 CEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 113 bits (273), Expect = 6e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 573
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 572 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 393
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 392 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 216
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 215 VSAECRKLITRIL 177
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein.
Length = 503
Score = 113 bits (273), Expect = 6e-25
Identities = 75/224 (33%), Positives = 119/224 (53%), Gaps = 8/224 (3%)
Frame = -3
Query: 770 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 591
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 113 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 172
Query: 590 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 420
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 173 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 227
Query: 419 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ-LLKQVQN 243
+T CG+ Y +PEIL+G Y P + D+WS+G++ Y ++ G PF D Q + +++ N
Sbjct: 228 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILN 286
Query: 242 KVSF---PREPKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 123
+ P +VS + L+ + I+ K R+ Q L PW+
Sbjct: 287 CEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 330
>AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase
protein.
Length = 384
Score = 113 bits (273), Expect = 6e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -3
Query: 770 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 609
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 608 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 444
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 443 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 264
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 263 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 93
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 92 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 3
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 113 bits (273), Expect = 6e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -3
Query: 752 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 573
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 572 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 393
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 392 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 216
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 215 VSAECRKLITRIL 177
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 126,601,020
Number of Sequences: 237096
Number of extensions: 2751601
Number of successful extensions: 12335
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 7985
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8748
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 11095746082
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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