Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmte14a17
(825 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 376 e-104
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 376 e-104
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 376 e-104
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 376 e-104
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 376 e-104
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 376 e-104
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 374 e-103
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 373 e-103
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 367 e-101
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 361 1e-99
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 331 2e-90
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 330 4e-90
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 330 4e-90
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 330 4e-90
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 328 1e-89
AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitra... 128 3e-29
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 100 7e-21
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 376 bits (924), Expect = e-104
Identities = 172/214 (80%), Positives = 189/214 (88%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q+ L + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA
Sbjct: 198 QMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQ 257
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R
Sbjct: 258 AMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYR 317
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA
Sbjct: 318 MYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLA 377
Query: 246 ICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 145
CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 378 ACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 376 bits (924), Expect = e-104
Identities = 172/214 (80%), Positives = 189/214 (88%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q+ L + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA
Sbjct: 198 QMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQ 257
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R
Sbjct: 258 AMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYR 317
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA
Sbjct: 318 MYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLA 377
Query: 246 ICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 145
CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 378 ACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 376 bits (924), Expect = e-104
Identities = 172/214 (80%), Positives = 189/214 (88%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q+ L + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA
Sbjct: 198 QMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQ 257
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R
Sbjct: 258 AMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYR 317
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA
Sbjct: 318 MYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLA 377
Query: 246 ICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 145
CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 378 ACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 376 bits (924), Expect = e-104
Identities = 172/214 (80%), Positives = 189/214 (88%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q+ L + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA
Sbjct: 198 QMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQ 257
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R
Sbjct: 258 AMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYR 317
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA
Sbjct: 318 MYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLA 377
Query: 246 ICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 145
CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 378 ACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 376 bits (924), Expect = e-104
Identities = 172/214 (80%), Positives = 189/214 (88%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q+ L + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA
Sbjct: 198 QMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQ 257
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R
Sbjct: 258 AMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYR 317
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA
Sbjct: 318 MYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLA 377
Query: 246 ICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 145
CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 378 ACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 376 bits (924), Expect = e-104
Identities = 172/214 (80%), Positives = 189/214 (88%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q+ L + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA
Sbjct: 198 QMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQ 257
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R
Sbjct: 258 AMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYR 317
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA
Sbjct: 318 MYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLA 377
Query: 246 ICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 145
CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 378 ACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 374 bits (921), Expect = e-103
Identities = 171/214 (79%), Positives = 189/214 (88%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q+ L + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA
Sbjct: 198 QMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQ 257
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAE+AHGTVTRH+R
Sbjct: 258 AMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAESAHGTVTRHYR 317
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA
Sbjct: 318 MYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLA 377
Query: 246 ICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 145
CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 378 ACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 373 bits (917), Expect = e-103
Identities = 171/214 (79%), Positives = 188/214 (87%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q+ L + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA
Sbjct: 198 QMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQ 257
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R
Sbjct: 258 AMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYR 317
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTK LA
Sbjct: 318 MYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKGLA 377
Query: 246 ICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 145
CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 378 ACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 367 bits (903), Expect = e-101
Identities = 169/214 (78%), Positives = 187/214 (87%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q+ L + +PLYLSTKNTILK YDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA
Sbjct: 198 QMALSKGWPLYLSTKNTILKIYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQ 257
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R
Sbjct: 258 AMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYR 317
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
YQ+G+ETSTN IASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA
Sbjct: 318 MYQKGQETSTNLIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLA 377
Query: 246 ICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 145
CI+G+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 378 ACIRGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 361 bits (889), Expect = 1e-99
Identities = 165/203 (81%), Positives = 181/203 (89%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q+ L + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDDMVA
Sbjct: 169 QMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDDMVAQ 228
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH+R
Sbjct: 229 AMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRHYR 288
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKDLA
Sbjct: 289 MYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKDLA 348
Query: 246 ICIKGMNNVKRSDYYETFEFMDK 178
CIKG+ NV+RSDY TFEFMDK
Sbjct: 349 ACIKGLPNVQRSDYLNTFEFMDK 371
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 331 bits (813), Expect = 2e-90
Identities = 149/215 (69%), Positives = 179/215 (83%), Gaps = 1/215 (0%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q + +K+PLY+STKNTILK YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA
Sbjct: 237 QYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQ 296
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
+KS GGFVWACKNYDGDVQSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R
Sbjct: 297 VLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYR 356
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
+Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA
Sbjct: 357 EHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLA 416
Query: 246 ICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 145
CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 417 GCIHGLSNVKLNEHFLNTMDFLDTIKSNLDRALGR 451
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 330 bits (811), Expect = 4e-90
Identities = 149/215 (69%), Positives = 179/215 (83%), Gaps = 1/215 (0%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q + +K+PLY+STKNTILK YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA
Sbjct: 204 QYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQ 263
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
+KS GGFVWACKNYDGDVQSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R
Sbjct: 264 VLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYR 323
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
+Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA
Sbjct: 324 EHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLA 383
Query: 246 ICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 145
CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 384 GCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 418
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 330 bits (811), Expect = 4e-90
Identities = 149/215 (69%), Positives = 179/215 (83%), Gaps = 1/215 (0%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q + +K+PLY+STKNTILK YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA
Sbjct: 237 QYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQ 296
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
+KS GGFVWACKNYDGDVQSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R
Sbjct: 297 VLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYR 356
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
+Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA
Sbjct: 357 EHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLA 416
Query: 246 ICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 145
CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 417 GCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 330 bits (811), Expect = 4e-90
Identities = 149/215 (69%), Positives = 179/215 (83%), Gaps = 1/215 (0%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q + +K+PLY+STKNTILK YDGRFKDIFQ+I+D+ YK F+ IWYEHRLIDDMVA
Sbjct: 237 QYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQ 296
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
+KS GGFVWACKNYDGDVQSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R
Sbjct: 297 VLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYR 356
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
+Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA
Sbjct: 357 EHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLA 416
Query: 246 ICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 145
CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 417 GCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 328 bits (807), Expect = 1e-89
Identities = 148/215 (68%), Positives = 179/215 (83%), Gaps = 1/215 (0%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDDMVAY 607
Q + +K+PLY+STKNTILK YDGRFKDIFQ+I+D+ Y+ F+ IWYEHRLIDDMVA
Sbjct: 237 QYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYETDFDKNKIWYEHRLIDDMVAQ 296
Query: 606 AMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRHFR 427
+KS GGFVWACKNYDGDVQSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH+R
Sbjct: 297 VLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYR 356
Query: 426 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLA 247
+Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKDLA
Sbjct: 357 EHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKDLA 416
Query: 246 ICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 145
CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 417 GCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
>AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitrate
dehydrogenase protein.
Length = 127
Score = 128 bits (308), Expect = 3e-29
Identities = 61/89 (68%), Positives = 69/89 (77%)
Frame = -1
Query: 411 KETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKG 232
+E STNPIASIFAWTRGL RAK DNN L FA LE+VCIETIE+G MTKDLA CIKG
Sbjct: 1 QEISTNPIASIFAWTRGLALRAKTDNNKELAFFANALEEVCIETIEAGFMTKDLAACIKG 60
Query: 231 MNNVKRSDYYETFEFMDKLAENLKVALGQ 145
+ + + SDY TFEFM+KL ENLK+ L Q
Sbjct: 61 LPSAQCSDYLNTFEFMEKLGENLKIKLAQ 89
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 100 bits (239), Expect = 7e-21
Identities = 43/56 (76%), Positives = 49/56 (87%)
Frame = -1
Query: 786 QVCLDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKQFEDAGIWYEHRLIDD 619
Q+ L + +PLYLSTKNTILKKYDGRFKDIFQ+IYD++YK QFE IWYEHRLIDD
Sbjct: 99 QMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFEAQKIWYEHRLIDD 154
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,554,552
Number of Sequences: 237096
Number of extensions: 2320254
Number of successful extensions: 3902
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 3713
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3895
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10315140830
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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