Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmte13i15
(713 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AK075192-1|BAC11461.1| 630|Homo sapiens protein ( Homo sapiens ... 133 5e-31
BC006524-1|AAH06524.1| 630|Homo sapiens eukaryotic translation ... 133 7e-31
AF255050-1|AAF70289.1| 629|Homo sapiens heme-regulated eukaryot... 133 7e-31
AF183414-1|AAG09683.1| 630|Homo sapiens hemin-sensitive initiat... 133 7e-31
AF181071-1|AAF18391.1| 630|Homo sapiens heme-regulated initiati... 133 7e-31
AF147094-1|AAF66736.1| 629|Homo sapiens heme-regulated initiati... 133 7e-31
AF100784-1|AAP97223.1| 630|Homo sapiens hemin-sensitive initita... 133 7e-31
AC005995-1|AAS00388.1| 386|Homo sapiens unknown protein. 133 7e-31
AB037790-1|BAA92607.1| 653|Homo sapiens KIAA1369 protein protein. 133 7e-31
BC126356-1|AAI26357.1| 1115|Homo sapiens eukaryotic translation ... 101 3e-21
BC126354-1|AAI26355.1| 1116|Homo sapiens eukaryotic translation ... 101 3e-21
AF284615-1|AAF91480.1| 1115|Homo sapiens initiation factor 2-alp... 101 3e-21
AF193339-1|AAF61199.1| 1115|Homo sapiens eukaryotic translation ... 101 3e-21
AF110146-1|AAD19961.1| 1115|Homo sapiens eukaryotic translation ... 101 3e-21
AC104134-2|AAY24331.1| 970|Homo sapiens unknown protein. 101 3e-21
U50648-1|AAC50768.1| 551|Homo sapiens interferon-inducible RNA-... 95 2e-19
M85294-1|AAA18253.1| 551|Homo sapiens P1/eIF-2a protein kinase ... 95 2e-19
M35663-1|AAA36409.1| 551|Homo sapiens protein ( Human p68 kinas... 95 2e-19
BC101475-1|AAI01476.1| 551|Homo sapiens eukaryotic translation ... 95 2e-19
BC093676-1|AAH93676.1| 551|Homo sapiens eukaryotic translation ... 95 2e-19
AY302136-1|AAP57628.1| 510|Homo sapiens interferon-inducible do... 95 2e-19
AY228338-1|AAO38055.1| 551|Homo sapiens protein kinase, interfe... 95 2e-19
AC007899-1|AAY24317.1| 551|Homo sapiens unknown protein. 95 2e-19
AF167472-1|AAF13156.1| 551|Homo sapiens double stranded RNA act... 93 1e-18
BC057805-1|AAH57805.1| 513|Homo sapiens EIF2AK2 protein protein. 87 8e-17
BC040851-1|AAH40851.1| 513|Homo sapiens EIF2AK2 protein protein. 87 8e-17
D87116-1|BAA13248.1| 347|Homo sapiens MAP kinase kinase 3b prot... 74 6e-13
CR541793-1|CAG46592.1| 347|Homo sapiens MAP2K3 protein. 74 6e-13
CR536514-1|CAG38752.1| 347|Homo sapiens MAP2K3 protein. 74 6e-13
BC032478-1|AAH32478.1| 347|Homo sapiens mitogen-activated prote... 74 6e-13
AK223490-1|BAD97210.1| 347|Homo sapiens mitogen-activated prote... 74 6e-13
Z84469-2|CAI42732.1| 1790|Homo sapiens WNK lysine deficient prot... 73 8e-13
Z84469-1|CAI42733.1| 1743|Homo sapiens WNK lysine deficient prot... 73 8e-13
AY352048-1|AAR89465.1| 1800|Homo sapiens putative protein kinase... 73 8e-13
AY082340-1|AAL99253.1| 1800|Homo sapiens putative protein kinase... 73 8e-13
AL591766-2|CAI40707.1| 1790|Homo sapiens WNK lysine deficient pr... 73 8e-13
AL591766-1|CAI40708.1| 1743|Homo sapiens WNK lysine deficient pr... 73 8e-13
AL049793-2|CAI43128.1| 1790|Homo sapiens WNK lysine deficient pr... 73 8e-13
AL049793-1|CAI43129.1| 1743|Homo sapiens WNK lysine deficient pr... 73 8e-13
AJ409088-1|CAC32455.2| 1743|Homo sapiens protein kinase WNK3 pro... 73 8e-13
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 73 1e-12
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 73 1e-12
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 73 1e-12
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 73 1e-12
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 73 1e-12
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 73 1e-12
U66840-1|AAB40653.1| 352|Homo sapiens MAP kinase 3c protein. 72 2e-12
U66839-1|AAB40652.1| 347|Homo sapiens MAP kinase 3b protein. 72 2e-12
L36719-1|AAC41718.1| 318|Homo sapiens MAP kinase kinase 3 protein. 72 2e-12
X69117-1|CAA48870.1| 688|Homo sapiens beta-adrenergic kinase 2 ... 70 7e-12
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 70 7e-12
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 70 7e-12
L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein. 70 1e-11
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 70 1e-11
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 69 1e-11
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 69 1e-11
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 69 1e-11
AL022329-1|CAB45657.1| 688|Homo sapiens adrenergic, beta, recep... 69 1e-11
AK096052-1|BAC04688.1| 663|Homo sapiens protein ( Homo sapiens ... 69 1e-11
AJ316534-1|CAC48387.1| 1231|Homo sapiens serine/threonine protei... 69 1e-11
AF390018-1|AAK91995.1| 1243|Homo sapiens putative protein kinase... 69 1e-11
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 69 1e-11
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 69 1e-11
X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for ... 69 2e-11
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 69 2e-11
BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein. 69 2e-11
BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein. 69 2e-11
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 69 2e-11
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 69 2e-11
BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia... 69 2e-11
AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia... 69 2e-11
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 69 2e-11
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 69 2e-11
AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase... 69 2e-11
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 69 2e-11
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 69 2e-11
AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase... 69 2e-11
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 69 2e-11
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 69 2e-11
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 69 2e-11
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 69 2e-11
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 69 2e-11
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 69 2e-11
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 69 2e-11
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 69 2e-11
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 69 2e-11
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 69 2e-11
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 69 2e-11
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 69 2e-11
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 69 2e-11
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 69 2e-11
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 69 2e-11
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 69 2e-11
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 68 3e-11
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 68 3e-11
EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein. 68 3e-11
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 68 3e-11
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 68 3e-11
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 68 3e-11
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 68 3e-11
AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kina... 68 3e-11
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 68 3e-11
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 68 4e-11
U56816-1|AAC50949.1| 499|Homo sapiens kinase Myt1 protein. 67 5e-11
L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-depend... 67 5e-11
BC130011-1|AAI30012.1| 485|Homo sapiens PKMYT1 protein protein. 67 5e-11
BC121162-1|AAI21163.1| 485|Homo sapiens PKMYT1 protein protein. 67 5e-11
BC121161-1|AAI21162.1| 485|Homo sapiens PKMYT1 protein protein. 67 5e-11
BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein. 67 5e-11
AL713896-5|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 67 5e-11
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 67 5e-11
AL713896-1|CAI13787.1| 453|Homo sapiens calcium/calmodulin-depe... 67 5e-11
AL596247-5|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 67 5e-11
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 67 5e-11
AL596247-1|CAI13964.1| 453|Homo sapiens calcium/calmodulin-depe... 67 5e-11
AF549406-1|AAN40703.1| 499|Homo sapiens membrane-associated tyr... 67 5e-11
AF014118-1|AAB71843.1| 499|Homo sapiens membrane-associated kin... 67 5e-11
AC004235-1|AAC04477.1| 495|Homo sapiens Myt1 protein. 67 5e-11
AC004233-1|AAC04478.1| 499|Homo sapiens Myt1 protein. 67 5e-11
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 67 7e-11
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 67 7e-11
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 67 7e-11
AL713896-3|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 67 7e-11
AL713896-2|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 67 7e-11
AL596247-3|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 67 7e-11
AL596247-2|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 67 7e-11
AJ296290-1|CAC15059.1| 2382|Homo sapiens putative protein kinase... 67 7e-11
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 67 7e-11
AF061944-1|AAF31483.1| 670|Homo sapiens kinase deficient protei... 67 7e-11
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 67 7e-11
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 67 7e-11
AB002342-1|BAA20802.2| 2066|Homo sapiens KIAA0344 protein. 67 7e-11
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 66 9e-11
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 66 9e-11
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 66 9e-11
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 66 9e-11
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 66 9e-11
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 66 9e-11
AL583839-7|CAO03350.1| 2219|Homo sapiens WNK lysine deficient pr... 66 9e-11
AL583839-6|CAI12344.3| 2297|Homo sapiens WNK lysine deficient pr... 66 9e-11
AL390760-3|CAO03647.1| 2219|Homo sapiens WNK lysine deficient pr... 66 9e-11
AL390760-2|CAO03646.1| 790|Homo sapiens WNK lysine deficient pr... 66 9e-11
AL390760-1|CAH73069.3| 2297|Homo sapiens WNK lysine deficient pr... 66 9e-11
AL354991-3|CAO03639.1| 2219|Homo sapiens WNK lysine deficient pr... 66 9e-11
AL354991-2|CAI14449.3| 2297|Homo sapiens WNK lysine deficient pr... 66 9e-11
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 66 9e-11
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 66 9e-11
AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens ... 66 9e-11
AK000556-1|BAA91251.1| 293|Homo sapiens protein ( Homo sapiens ... 66 9e-11
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 66 9e-11
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 66 9e-11
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 66 9e-11
AJ242724-1|CAB44308.5| 2297|Homo sapiens putative mitogen-activa... 66 9e-11
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 66 9e-11
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 66 9e-11
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 66 9e-11
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 66 9e-11
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 66 9e-11
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 66 9e-11
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 66 9e-11
AB051547-1|BAB21851.2| 2219|Homo sapiens KIAA1760 protein protein. 66 9e-11
AB044546-1|BAB18648.1| 779|Homo sapiens mitogen-activated prote... 66 9e-11
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 66 9e-11
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 66 9e-11
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 66 1e-10
M80776-1|AAA58391.1| 689|Homo sapiens receptor kinase protein. 66 1e-10
BC090863-1|AAH90863.1| 689|Homo sapiens ADRBK1 protein protein. 66 1e-10
BC037963-1|AAH37963.1| 689|Homo sapiens adrenergic, beta, recep... 66 1e-10
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 66 1e-10
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 66 1e-10
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 66 1e-10
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 66 1e-10
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 66 1e-10
X61157-1|CAA43470.1| 689|Homo sapiens beta-adrenergic receptor ... 66 2e-10
U08438-1|AAB60689.1| 689|Homo sapiens beta-adrenergic receptor ... 66 2e-10
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 66 2e-10
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 66 2e-10
AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein. 66 2e-10
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 65 2e-10
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 65 2e-10
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 65 2e-10
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 65 2e-10
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 65 2e-10
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 65 2e-10
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 65 2e-10
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 65 2e-10
AJ309861-1|CAC32991.1| 212|Homo sapiens putative protein kinase... 65 2e-10
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 65 3e-10
X59727-1|CAA42411.1| 557|Homo sapiens 63kDa protein kinase prot... 65 3e-10
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 65 3e-10
BC117216-1|AAI17217.1| 587|Homo sapiens mitogen-activated prote... 65 3e-10
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 65 3e-10
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 65 3e-10
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 65 3e-10
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 65 3e-10
BC050299-1|AAH50299.1| 587|Homo sapiens mitogen-activated prote... 64 4e-10
BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1 receptor-... 64 4e-10
AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor ... 64 4e-10
AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1 receptor-... 64 4e-10
AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1 receptor-... 64 4e-10
AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1 receptor-... 64 4e-10
AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1 receptor-... 64 4e-10
AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1 receptor-... 64 4e-10
AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1 receptor-... 64 4e-10
AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1 receptor-... 64 4e-10
AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens ... 64 4e-10
AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens ... 64 4e-10
AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor ... 64 4e-10
AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase... 64 4e-10
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 64 5e-10
BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein. 64 5e-10
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 64 5e-10
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 64 5e-10
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 64 5e-10
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 64 5e-10
AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase... 64 5e-10
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 64 5e-10
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 64 5e-10
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 64 5e-10
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 64 5e-10
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 64 5e-10
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 64 5e-10
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 64 5e-10
AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein. 64 5e-10
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 64 6e-10
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 64 6e-10
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 64 6e-10
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 64 6e-10
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 63 8e-10
BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated prote... 63 8e-10
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 63 8e-10
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 63 8e-10
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 63 8e-10
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 63 8e-10
AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein. 63 8e-10
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 63 8e-10
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 63 1e-09
U71088-1|AAB16852.2| 444|Homo sapiens MAP kinase kinase MEK5c p... 63 1e-09
U25265-1|AAA96146.1| 438|Homo sapiens MEK5 protein. 63 1e-09
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 63 1e-09
D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein. 63 1e-09
BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein. 63 1e-09
BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein. 63 1e-09
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 63 1e-09
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 63 1e-09
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 63 1e-09
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 63 1e-09
AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase ... 63 1e-09
AF507907-1|AAM50515.1| 244|Homo sapiens testis-specific kinase-... 63 1e-09
AB209179-1|BAD92416.1| 546|Homo sapiens polo-like kinase varian... 63 1e-09
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 63 1e-09
Y14440-1|CAA74792.1| 364|Homo sapiens stress activated protein ... 62 1e-09
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 62 1e-09
U92268-1|AAB66313.1| 364|Homo sapiens mitogen activated protein... 62 1e-09
DQ279722-1|ABB72677.1| 364|Homo sapiens mitogen-activated prote... 62 1e-09
CR456514-1|CAG30400.1| 364|Homo sapiens MAPK11 protein. 62 1e-09
BC027933-1|AAH27933.1| 364|Homo sapiens mitogen-activated prote... 62 1e-09
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 62 1e-09
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 62 1e-09
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 62 1e-09
AL022328-13|CAB51539.1| 364|Homo sapiens mitogen-activated prot... 62 1e-09
AF031135-1|AAC12714.1| 364|Homo sapiens p38beta2 MAP kinase pro... 62 1e-09
AF001174-1|AAC51373.1| 364|Homo sapiens p38beta2 MAP kinase pro... 62 1e-09
AF001008-1|AAC51250.1| 364|Homo sapiens p38Beta2 MAP Kinase pro... 62 1e-09
Z84466-8|CAI42468.1| 606|Homo sapiens v-raf murine sarcoma 3611... 62 2e-09
X04790-1|CAA28476.1| 606|Homo sapiens protein ( Human mRNA for ... 62 2e-09
U71087-1|AAB16851.1| 448|Homo sapiens MAP kinase kinase MEK5b p... 62 2e-09
U53442-1|AAB05036.1| 372|Homo sapiens p38Beta MAP kinase protein. 62 2e-09
U07747-1|AAA19647.1| 847|Homo sapiens serine/threonine protein ... 62 2e-09
U01337-1|AAB03517.1| 606|Homo sapiens Ser/Thr protein kinase pr... 62 2e-09
L32976-1|AAA59859.1| 847|Homo sapiens protein kinase protein. 62 2e-09
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 62 2e-09
L24038-1|AAA65219.1| 606|Homo sapiens ARAF1 protein. 62 2e-09
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 62 2e-09
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 62 2e-09
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 62 2e-09
CR542229-1|CAG47025.1| 448|Homo sapiens MAP2K5 protein. 62 2e-09
BT019864-1|AAV38667.1| 606|Homo sapiens v-raf murine sarcoma 36... 62 2e-09
BT006780-1|AAP35426.1| 448|Homo sapiens mitogen-activated prote... 62 2e-09
BC036797-1|AAH36797.1| 387|Homo sapiens ADRBK2 protein protein. 62 2e-09
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 62 2e-09
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 62 2e-09
BC011263-1|AAH11263.1| 847|Homo sapiens mitogen-activated prote... 62 2e-09
BC008838-1|AAH08838.1| 448|Homo sapiens mitogen-activated prote... 62 2e-09
BC007514-1|AAH07514.1| 609|Homo sapiens ARAF protein protein. 62 2e-09
BC002466-1|AAH02466.1| 606|Homo sapiens v-raf murine sarcoma 36... 62 2e-09
AK222781-1|BAD96501.1| 847|Homo sapiens mitogen-activated prote... 62 2e-09
BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein. 62 3e-09
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 62 3e-09
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 62 3e-09
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 62 3e-09
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 62 3e-09
BT019655-1|AAV38461.1| 606|Homo sapiens mitogen-activated prote... 61 3e-09
BC133706-1|AAI33707.1| 1104|Homo sapiens MAP3K9 protein protein. 61 3e-09
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 61 3e-09
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 61 3e-09
BC111407-1|AAI11408.1| 1103|Homo sapiens MAP3K9 protein protein. 61 3e-09
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 61 3e-09
AY327900-1|AAQ23054.1| 1104|Homo sapiens mixed-lineage protein k... 61 3e-09
AF251442-1|AAG44591.1| 1066|Homo sapiens mixed lineage kinase ML... 61 3e-09
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 61 3e-09
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 61 3e-09
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 61 4e-09
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 61 4e-09
M13829-1|AAB08754.1| 298|Homo sapiens raf related protein protein. 61 4e-09
CR542222-1|CAG47018.1| 306|Homo sapiens NEK6 protein. 61 4e-09
CR457091-1|CAG33372.1| 306|Homo sapiens NEK6 protein. 61 4e-09
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 61 4e-09
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 61 4e-09
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 61 4e-09
BC012761-1|AAH12761.1| 313|Homo sapiens NIMA (never in mitosis ... 61 4e-09
BC004209-1|AAH04209.2| 313|Homo sapiens NEK6 protein protein. 61 4e-09
BC004174-1|AAH04174.2| 313|Homo sapiens NEK6 protein protein. 61 4e-09
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 61 4e-09
BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein. 61 4e-09
BC000101-1|AAH00101.2| 313|Homo sapiens NEK6 protein protein. 61 4e-09
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 61 4e-09
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 61 4e-09
AL162724-9|CAH70254.1| 313|Homo sapiens NIMA (never in mitosis ... 61 4e-09
AL162724-2|CAH70247.1| 347|Homo sapiens NIMA (never in mitosis ... 61 4e-09
AL137846-13|CAI10883.1| 313|Homo sapiens NIMA (never in mitosis... 61 4e-09
AL137846-6|CAI10876.1| 347|Homo sapiens NIMA (never in mitosis ... 61 4e-09
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 61 4e-09
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 61 4e-09
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 61 4e-09
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 61 4e-09
AF087909-1|AAG13417.1| 338|Homo sapiens NIMA-related kinase 6 p... 61 4e-09
AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens ... 61 4e-09
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 61 4e-09
AB026289-1|BAA85045.1| 306|Homo sapiens protein kinase SID6-151... 61 4e-09
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 61 4e-09
AL162724-8|CAH70253.1| 201|Homo sapiens NIMA (never in mitosis ... 60 6e-09
AL137846-12|CAI10882.1| 201|Homo sapiens NIMA (never in mitosis... 60 6e-09
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 60 6e-09
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 60 8e-09
DQ316259-1|ABC40748.1| 516|Homo sapiens nemo like kinase protein. 60 8e-09
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 60 8e-09
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 60 8e-09
BC064663-1|AAH64663.1| 515|Homo sapiens nemo-like kinase protein. 60 8e-09
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 60 8e-09
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 60 8e-09
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 60 8e-09
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 60 8e-09
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 60 8e-09
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 60 8e-09
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 60 8e-09
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 60 8e-09
AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens ... 60 8e-09
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 60 8e-09
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 60 8e-09
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 60 8e-09
AF197898-1|AAF04857.1| 515|Homo sapiens nemo-like kinase protein. 60 8e-09
AF180819-1|AAD56013.1| 515|Homo sapiens LAK1 protein protein. 60 8e-09
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 60 8e-09
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 60 8e-09
AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein. 60 8e-09
BC070077-1|AAH70077.1| 968|Homo sapiens serine/threonine kinase... 60 1e-08
AB015718-1|BAA35073.1| 968|Homo sapiens protein kinase protein. 60 1e-08
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 59 1e-08
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 59 1e-08
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 59 1e-08
DQ314875-1|ABC40734.1| 606|Homo sapiens mitogen-activated prote... 59 1e-08
BT019654-1|AAV38460.1| 579|Homo sapiens mitogen-activated prote... 59 1e-08
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 59 1e-08
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 59 1e-08
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 59 1e-08
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 59 1e-08
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 59 1e-08
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 59 1e-08
BC017715-1|AAH17715.1| 579|Homo sapiens mitogen-activated prote... 59 1e-08
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 59 1e-08
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 59 1e-08
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 59 1e-08
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 59 1e-08
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 59 1e-08
AL121964-4|CAI19611.1| 579|Homo sapiens mitogen-activated prote... 59 1e-08
AL121964-3|CAI19612.1| 606|Homo sapiens mitogen-activated prote... 59 1e-08
AL121964-2|CAI19609.1| 491|Homo sapiens mitogen-activated prote... 59 1e-08
AL121964-1|CAI19610.1| 518|Homo sapiens mitogen-activated prote... 59 1e-08
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 59 1e-08
AL121837-4|CAI23533.1| 579|Homo sapiens mitogen-activated prote... 59 1e-08
AL121837-3|CAI23532.1| 606|Homo sapiens mitogen-activated prote... 59 1e-08
AL121837-2|CAI23531.1| 491|Homo sapiens mitogen-activated prote... 59 1e-08
AL121837-1|CAI23530.1| 518|Homo sapiens mitogen-activated prote... 59 1e-08
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 59 1e-08
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 59 1e-08
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 59 1e-08
AF218074-1|AAF27652.1| 491|Homo sapiens TGF beta-activated kina... 59 1e-08
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 59 1e-08
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 59 1e-08
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 59 1e-08
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 59 1e-08
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 59 1e-08
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 59 1e-08
AB009358-1|BAA25027.2| 518|Homo sapiens TGF-beta activated kina... 59 1e-08
AB009357-1|BAA25026.1| 606|Homo sapiens TGF-beta activated kina... 59 1e-08
AB009356-1|BAA25025.1| 579|Homo sapiens TGF-beta activated kina... 59 1e-08
X80692-1|CAA56709.1| 721|Homo sapiens p97mapk protein. 59 2e-08
L77964-1|AAA98769.1| 721|Homo sapiens ERK3 protein kinase protein. 59 2e-08
BC150256-1|AAI50257.1| 1360|Homo sapiens TRAF2 and NCK interacti... 59 2e-08
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 59 2e-08
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 59 2e-08
BC035492-1|AAH35492.1| 721|Homo sapiens mitogen-activated prote... 59 2e-08
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 59 2e-08
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 59 2e-08
AK055778-1|BAB71011.1| 1113|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AF420474-1|AAL17605.1| 721|Homo sapiens ERK-3 protein. 59 2e-08
AF391558-1|AAO13803.1| 1192|Homo sapiens myosin IIIB variant MYO... 59 2e-08
AF391557-1|AAO13802.1| 1275|Homo sapiens myosin IIIB variant MYO... 59 2e-08
AF391556-1|AAO13801.1| 1314|Homo sapiens myosin IIIB variant MYO... 59 2e-08
AF391555-1|AAO13800.1| 1341|Homo sapiens myosin IIIB variant MYO... 59 2e-08
AF391554-1|AAO13799.1| 1251|Homo sapiens myosin IIIB variant MYO... 59 2e-08
AF369908-1|AAL57233.1| 1278|Homo sapiens myosin IIIB protein. 59 2e-08
AF172271-1|AAF03789.1| 1268|Homo sapiens Traf2 and NCK interacti... 59 2e-08
AF172270-1|AAF03788.1| 1297|Homo sapiens Traf2 and NCK interacti... 59 2e-08
AF172269-1|AAF03787.1| 1323|Homo sapiens Traf2 and NCK interacti... 59 2e-08
AF172268-1|AAF03786.1| 1276|Homo sapiens Traf2 and NCK interacti... 59 2e-08
AF172267-1|AAF03785.1| 1352|Homo sapiens Traf2 and NCK interacti... 59 2e-08
AF172266-1|AAF03784.1| 1305|Homo sapiens Traf2 and NCK interacti... 59 2e-08
AF172265-1|AAF03783.1| 1331|Homo sapiens Traf2 and NCK interacti... 59 2e-08
AF172264-1|AAF03782.1| 1360|Homo sapiens Traf2 and NCK interacti... 59 2e-08
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 59 2e-08
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 59 2e-08
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 59 2e-08
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 59 2e-08
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 59 2e-08
AB011123-1|BAA25477.2| 1385|Homo sapiens KIAA0551 protein protein. 59 2e-08
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 58 2e-08
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 58 2e-08
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 58 2e-08
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 58 2e-08
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 58 2e-08
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 58 2e-08
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 58 2e-08
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 58 2e-08
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 58 2e-08
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 58 2e-08
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 58 2e-08
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 58 2e-08
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 58 2e-08
BC047696-1|AAH47696.1| 414|Homo sapiens serine/threonine kinase... 58 2e-08
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 58 2e-08
BC023508-1|AAH23508.2| 414|Homo sapiens serine/threonine kinase... 58 2e-08
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 58 2e-08
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 58 2e-08
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 58 2e-08
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 58 2e-08
BC007753-1|AAH07753.1| 242|Homo sapiens Unknown (protein for IM... 58 2e-08
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 58 2e-08
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 58 2e-08
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 58 2e-08
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 58 2e-08
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 58 2e-08
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 58 2e-08
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 58 2e-08
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 58 2e-08
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 58 2e-08
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 58 2e-08
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 58 2e-08
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 58 2e-08
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 58 2e-08
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 58 2e-08
AB183428-1|BAF73616.1| 580|Homo sapiens maternal embryonic luec... 58 2e-08
AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leuc... 58 2e-08
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 58 2e-08
AB011420-1|BAA34126.1| 414|Homo sapiens DRAK1 protein. 58 2e-08
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 58 3e-08
L40027-1|AAA62432.1| 483|Homo sapiens glycogen synthase kinase ... 58 3e-08
D63424-1|BAA23608.1| 483|Homo sapiens glycogen synthase kinase ... 58 3e-08
BC064422-1|AAH64422.1| 241|Homo sapiens PNCK protein protein. 58 3e-08
BC051865-1|AAH51865.1| 483|Homo sapiens glycogen synthase kinas... 58 3e-08
BC033085-1|AAH33085.1| 542|Homo sapiens TESK2 protein protein. 58 3e-08
BC027984-1|AAH27984.1| 483|Homo sapiens glycogen synthase kinas... 58 3e-08
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 58 3e-08
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 58 3e-08
AL451136-3|CAI13093.1| 571|Homo sapiens testis-specific kinase ... 58 3e-08
AL451136-2|CAI13092.1| 542|Homo sapiens testis-specific kinase ... 58 3e-08
AL359540-13|CAI21724.1| 571|Homo sapiens testis-specific kinase... 58 3e-08
AL359540-12|CAI21723.1| 542|Homo sapiens testis-specific kinase... 58 3e-08
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 58 3e-08
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 58 3e-08
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 58 3e-08
AJ132545-1|CAB41970.1| 555|Homo sapiens protein kinase protein. 58 3e-08
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 58 3e-08
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 58 3e-08
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 58 3e-08
AC006486-1|AAD11986.1| 483|Homo sapiens KG3A_HUMAN protein. 58 3e-08
AB057597-1|BAB62909.1| 571|Homo sapiens testicular protein kina... 58 3e-08
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 58 4e-08
BX538081-1|CAD98005.1| 303|Homo sapiens hypothetical protein pr... 58 4e-08
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 58 4e-08
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 58 4e-08
BC018645-1|AAH18645.1| 400|Homo sapiens mitogen-activated prote... 58 4e-08
BC000471-1|AAH00471.1| 400|Homo sapiens mitogen-activated prote... 58 4e-08
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 58 4e-08
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 58 4e-08
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 58 4e-08
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 58 4e-08
AF042838-1|AAC97073.1| 1495|Homo sapiens MEK kinase 1 protein. 58 4e-08
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 58 4e-08
>AK075192-1|BAC11461.1| 630|Homo sapiens protein ( Homo sapiens
cDNA FLJ90711 fis, clone PLACE1008282, highly similar to
HEME-REGULATED EUKARYOTIC INITIATION FACTOR EIF-2-ALPHA
KINASE ).
Length = 630
Score = 133 bits (322), Expect = 5e-31
Identities = 80/194 (41%), Positives = 117/194 (60%), Gaps = 15/194 (7%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP--LQQ-----SH 402
+F +LV G+ YIH+ GI+H D+KP N+F+ H V++GDFGLAC LQ+ +
Sbjct: 422 IFQELVEGVFYIHNMGIVHRDLKPRNIFL--HGPDQQVKIGDFGLACTDILQKNTDWTNR 479
Query: 401 SGLALGTH-------MYAAPEQLDG-QCNPKSDMYSLGIILLELVEPFVTDMERVKTITD 246
+G TH +YA+PEQL+G + + KSDMYSLG++LLEL +PF T+MER + +T
Sbjct: 480 NGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTG 539
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREEL 66
LR GQ+P L P A I L +R S+R QLL+ L +N + +L+ ++
Sbjct: 540 LRTGQLPESLRKRCPVQARYIQHLTRRNSSQRPSAIQLLQ--SELFQNSGNVNLTLQMKI 597
Query: 65 AAKDDEIAKLKMML 24
++ EIA+LK L
Sbjct: 598 IEQEKEIAELKKQL 611
>BC006524-1|AAH06524.1| 630|Homo sapiens eukaryotic translation
initiation factor 2-alpha kinase 1 protein.
Length = 630
Score = 133 bits (321), Expect = 7e-31
Identities = 80/194 (41%), Positives = 117/194 (60%), Gaps = 15/194 (7%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP--LQQ-----SH 402
+F +LV G+ YIH+ GI+H D+KP N+F+ H V++GDFGLAC LQ+ +
Sbjct: 422 IFQELVEGVFYIHNMGIVHRDLKPRNIFL--HGPDQQVKIGDFGLACTDILQKNTDWTNR 479
Query: 401 SGLALGTH-------MYAAPEQLDG-QCNPKSDMYSLGIILLELVEPFVTDMERVKTITD 246
+G TH +YA+PEQL+G + + KSDMYSLG++LLEL +PF T+MER + +T
Sbjct: 480 NGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTG 539
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREEL 66
LR GQ+P L P A I L +R S+R QLL+ L +N + +L+ ++
Sbjct: 540 LRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQ--SELFQNSGNVNLTLQMKI 597
Query: 65 AAKDDEIAKLKMML 24
++ EIA+LK L
Sbjct: 598 IEQEKEIAELKKQL 611
>AF255050-1|AAF70289.1| 629|Homo sapiens heme-regulated eukaryotic
initiation factor 2 alpha kinase protein.
Length = 629
Score = 133 bits (321), Expect = 7e-31
Identities = 80/194 (41%), Positives = 117/194 (60%), Gaps = 15/194 (7%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP--LQQ-----SH 402
+F +LV G+ YIH+ GI+H D+KP N+F+ H V++GDFGLAC LQ+ +
Sbjct: 421 IFQELVEGVFYIHNMGIVHRDLKPRNIFL--HGPDQQVKIGDFGLACTDILQKNTDWTNR 478
Query: 401 SGLALGTH-------MYAAPEQLDG-QCNPKSDMYSLGIILLELVEPFVTDMERVKTITD 246
+G TH +YA+PEQL+G + + KSDMYSLG++LLEL +PF T+MER + +T
Sbjct: 479 NGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTG 538
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREEL 66
LR GQ+P L P A I L +R S+R QLL+ L +N + +L+ ++
Sbjct: 539 LRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQ--SELFQNSGNVNLTLQMKI 596
Query: 65 AAKDDEIAKLKMML 24
++ EIA+LK L
Sbjct: 597 IEQEKEIAELKKQL 610
>AF183414-1|AAG09683.1| 630|Homo sapiens hemin-sensitive initiation
factor 2a kinase protein.
Length = 630
Score = 133 bits (321), Expect = 7e-31
Identities = 80/194 (41%), Positives = 117/194 (60%), Gaps = 15/194 (7%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP--LQQ-----SH 402
+F +LV G+ YIH+ GI+H D+KP N+F+ H V++GDFGLAC LQ+ +
Sbjct: 422 IFQELVEGVFYIHNMGIVHRDLKPRNIFL--HGPDQQVKIGDFGLACTDILQKNTDWTNR 479
Query: 401 SGLALGTH-------MYAAPEQLDG-QCNPKSDMYSLGIILLELVEPFVTDMERVKTITD 246
+G TH +YA+PEQL+G + + KSDMYSLG++LLEL +PF T+MER + +T
Sbjct: 480 NGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTG 539
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREEL 66
LR GQ+P L P A I L +R S+R QLL+ L +N + +L+ ++
Sbjct: 540 LRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQ--SELFQNSGNVNLTLQMKI 597
Query: 65 AAKDDEIAKLKMML 24
++ EIA+LK L
Sbjct: 598 IEQEKEIAELKKQL 611
>AF181071-1|AAF18391.1| 630|Homo sapiens heme-regulated initiation
factor 2-alpha kinase protein.
Length = 630
Score = 133 bits (321), Expect = 7e-31
Identities = 80/194 (41%), Positives = 117/194 (60%), Gaps = 15/194 (7%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP--LQQ-----SH 402
+F +LV G+ YIH+ GI+H D+KP N+F+ H V++GDFGLAC LQ+ +
Sbjct: 422 IFQELVEGVFYIHNMGIVHRDLKPRNIFL--HGPDQQVKIGDFGLACTDILQKNTDWTNR 479
Query: 401 SGLALGTH-------MYAAPEQLDG-QCNPKSDMYSLGIILLELVEPFVTDMERVKTITD 246
+G TH +YA+PEQL+G + + KSDMYSLG++LLEL +PF T+MER + +T
Sbjct: 480 NGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTG 539
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREEL 66
LR GQ+P L P A I L +R S+R QLL+ L +N + +L+ ++
Sbjct: 540 LRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQ--SELFQNSGNVNLTLQMKI 597
Query: 65 AAKDDEIAKLKMML 24
++ EIA+LK L
Sbjct: 598 IEQEKEIAELKKQL 611
>AF147094-1|AAF66736.1| 629|Homo sapiens heme-regulated initiation
factor 2 alpha kinase protein.
Length = 629
Score = 133 bits (321), Expect = 7e-31
Identities = 80/194 (41%), Positives = 117/194 (60%), Gaps = 15/194 (7%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP--LQQ-----SH 402
+F +LV G+ YIH+ GI+H D+KP N+F+ H V++GDFGLAC LQ+ +
Sbjct: 421 IFQELVEGVFYIHNMGIVHRDLKPRNIFL--HGPDQQVKIGDFGLACTDILQKNTDWTNR 478
Query: 401 SGLALGTH-------MYAAPEQLDG-QCNPKSDMYSLGIILLELVEPFVTDMERVKTITD 246
+G TH +YA+PEQL+G + + KSDMYSLG++LLEL +PF T+MER + +T
Sbjct: 479 NGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTG 538
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREEL 66
LR GQ+P L P A I L +R S+R QLL+ L +N + +L+ ++
Sbjct: 539 LRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQ--SELFQNSGNVNLTLQMKI 596
Query: 65 AAKDDEIAKLKMML 24
++ EIA+LK L
Sbjct: 597 IEQEKEIAELKKQL 610
>AF100784-1|AAP97223.1| 630|Homo sapiens hemin-sensitive
inititation factor 2a kinase protein.
Length = 630
Score = 133 bits (321), Expect = 7e-31
Identities = 80/194 (41%), Positives = 117/194 (60%), Gaps = 15/194 (7%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP--LQQ-----SH 402
+F +LV G+ YIH+ GI+H D+KP N+F+ H V++GDFGLAC LQ+ +
Sbjct: 422 IFQELVEGVFYIHNMGIVHRDLKPRNIFL--HGPDQQVKIGDFGLACTDILQKNTDWTNR 479
Query: 401 SGLALGTH-------MYAAPEQLDG-QCNPKSDMYSLGIILLELVEPFVTDMERVKTITD 246
+G TH +YA+PEQL+G + + KSDMYSLG++LLEL +PF T+MER + +T
Sbjct: 480 NGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTG 539
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREEL 66
LR GQ+P L P A I L +R S+R QLL+ L +N + +L+ ++
Sbjct: 540 LRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQ--SELFQNSGNVNLTLQMKI 597
Query: 65 AAKDDEIAKLKMML 24
++ EIA+LK L
Sbjct: 598 IEQEKEIAELKKQL 611
>AC005995-1|AAS00388.1| 386|Homo sapiens unknown protein.
Length = 386
Score = 133 bits (321), Expect = 7e-31
Identities = 80/194 (41%), Positives = 117/194 (60%), Gaps = 15/194 (7%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP--LQQ-----SH 402
+F +LV G+ YIH+ GI+H D+KP N+F+ H V++GDFGLAC LQ+ +
Sbjct: 178 IFQELVEGVFYIHNMGIVHRDLKPRNIFL--HGPDQQVKIGDFGLACTDILQKNTDWTNR 235
Query: 401 SGLALGTH-------MYAAPEQLDG-QCNPKSDMYSLGIILLELVEPFVTDMERVKTITD 246
+G TH +YA+PEQL+G + + KSDMYSLG++LLEL +PF T+MER + +T
Sbjct: 236 NGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTG 295
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREEL 66
LR GQ+P L P A I L +R S+R QLL+ L +N + +L+ ++
Sbjct: 296 LRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQ--SELFQNSGNVNLTLQMKI 353
Query: 65 AAKDDEIAKLKMML 24
++ EIA+LK L
Sbjct: 354 IEQEKEIAELKKQL 367
>AB037790-1|BAA92607.1| 653|Homo sapiens KIAA1369 protein protein.
Length = 653
Score = 133 bits (321), Expect = 7e-31
Identities = 80/194 (41%), Positives = 117/194 (60%), Gaps = 15/194 (7%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP--LQQ-----SH 402
+F +LV G+ YIH+ GI+H D+KP N+F+ H V++GDFGLAC LQ+ +
Sbjct: 445 IFQELVEGVFYIHNMGIVHRDLKPRNIFL--HGPDQQVKIGDFGLACTDILQKNTDWTNR 502
Query: 401 SGLALGTH-------MYAAPEQLDG-QCNPKSDMYSLGIILLELVEPFVTDMERVKTITD 246
+G TH +YA+PEQL+G + + KSDMYSLG++LLEL +PF T+MER + +T
Sbjct: 503 NGKRTPTHTSRVGTCLYASPEQLEGSEYDAKSDMYSLGVVLLELFQPFGTEMERAEVLTG 562
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREEL 66
LR GQ+P L P A I L +R S+R QLL+ L +N + +L+ ++
Sbjct: 563 LRTGQLPESLRKRCPVQAKYIQHLTRRNSSQRPSAIQLLQ--SELFQNSGNVNLTLQMKI 620
Query: 65 AAKDDEIAKLKMML 24
++ EIA+LK L
Sbjct: 621 IEQEKEIAELKKQL 634
>BC126356-1|AAI26357.1| 1115|Homo sapiens eukaryotic translation
initiation factor 2-alpha kinase 3 protein.
Length = 1115
Score = 101 bits (242), Expect = 3e-21
Identities = 55/163 (33%), Positives = 93/163 (57%), Gaps = 16/163 (9%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS------ 405
+ +F Q+ + ++HS+G++H D+KPSN+F + +V++GDFGL + Q
Sbjct: 914 LHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDD---VVKVGDFGLVTAMDQDEEEQTV 970
Query: 404 ---------HSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLELVEPFVTDMERVKT 255
H+G +GT +Y +PEQ+ G + K D++SLG+IL EL+ PF T MERV+T
Sbjct: 971 LTPMPAYARHTG-QVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRT 1029
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+TD+R + P T YP ++ ++ P +R + ++E
Sbjct: 1030 LTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIE 1072
>BC126354-1|AAI26355.1| 1116|Homo sapiens eukaryotic translation
initiation factor 2-alpha kinase 3 protein.
Length = 1116
Score = 101 bits (242), Expect = 3e-21
Identities = 55/163 (33%), Positives = 93/163 (57%), Gaps = 16/163 (9%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS------ 405
+ +F Q+ + ++HS+G++H D+KPSN+F + +V++GDFGL + Q
Sbjct: 915 LHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDD---VVKVGDFGLVTAMDQDEEEQTV 971
Query: 404 ---------HSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLELVEPFVTDMERVKT 255
H+G +GT +Y +PEQ+ G + K D++SLG+IL EL+ PF T MERV+T
Sbjct: 972 LTPMPAYARHTG-QVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRT 1030
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+TD+R + P T YP ++ ++ P +R + ++E
Sbjct: 1031 LTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIE 1073
>AF284615-1|AAF91480.1| 1115|Homo sapiens initiation factor 2-alpha
kinase 3 protein.
Length = 1115
Score = 101 bits (242), Expect = 3e-21
Identities = 55/163 (33%), Positives = 93/163 (57%), Gaps = 16/163 (9%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS------ 405
+ +F Q+ + ++HS+G++H D+KPSN+F + +V++GDFGL + Q
Sbjct: 914 LHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDD---VVKVGDFGLVTAMDQDEEEQTV 970
Query: 404 ---------HSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLELVEPFVTDMERVKT 255
H+G +GT +Y +PEQ+ G + K D++SLG+IL EL+ PF T MERV+T
Sbjct: 971 LTPMPAYARHTG-QVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRT 1029
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+TD+R + P T YP ++ ++ P +R + ++E
Sbjct: 1030 LTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIE 1072
>AF193339-1|AAF61199.1| 1115|Homo sapiens eukaryotic translation
initiation factor 2 alpha kinase PEK protein.
Length = 1115
Score = 101 bits (242), Expect = 3e-21
Identities = 55/163 (33%), Positives = 93/163 (57%), Gaps = 16/163 (9%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS------ 405
+ +F Q+ + ++HS+G++H D+KPSN+F + +V++GDFGL + Q
Sbjct: 914 LHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDD---VVKVGDFGLVTAMDQDEEEQTV 970
Query: 404 ---------HSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLELVEPFVTDMERVKT 255
H+G +GT +Y +PEQ+ G + K D++SLG+IL EL+ PF T MERV+T
Sbjct: 971 LTPMPAYARHTG-QVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRT 1029
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+TD+R + P T YP ++ ++ P +R + ++E
Sbjct: 1030 LTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIE 1072
>AF110146-1|AAD19961.1| 1115|Homo sapiens eukaryotic translation
initiation factor 2 alpha kinase PEK protein.
Length = 1115
Score = 101 bits (242), Expect = 3e-21
Identities = 55/163 (33%), Positives = 93/163 (57%), Gaps = 16/163 (9%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS------ 405
+ +F Q+ + ++HS+G++H D+KPSN+F + +V++GDFGL + Q
Sbjct: 914 LHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDD---VVKVGDFGLVTAMDQDEEEQTV 970
Query: 404 ---------HSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLELVEPFVTDMERVKT 255
H+G +GT +Y +PEQ+ G + K D++SLG+IL EL+ PF T MERV+T
Sbjct: 971 LTPMPAYARHTG-QVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRT 1029
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+TD+R + P T YP ++ ++ P +R + ++E
Sbjct: 1030 LTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIE 1072
>AC104134-2|AAY24331.1| 970|Homo sapiens unknown protein.
Length = 970
Score = 101 bits (242), Expect = 3e-21
Identities = 55/163 (33%), Positives = 93/163 (57%), Gaps = 16/163 (9%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS------ 405
+ +F Q+ + ++HS+G++H D+KPSN+F + +V++GDFGL + Q
Sbjct: 769 LHIFLQIAEAVEFLHSKGLMHRDLKPSNIFFTMDD---VVKVGDFGLVTAMDQDEEEQTV 825
Query: 404 ---------HSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLELVEPFVTDMERVKT 255
H+G +GT +Y +PEQ+ G + K D++SLG+IL EL+ PF T MERV+T
Sbjct: 826 LTPMPAYARHTG-QVGTKLYMSPEQIHGNSYSHKVDIFSLGLILFELLYPFSTQMERVRT 884
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+TD+R + P T YP ++ ++ P +R + ++E
Sbjct: 885 LTDVRNLKFPPLFTQKYPCEYVMVQDMLSPSPMERPEAINIIE 927
>U50648-1|AAC50768.1| 551|Homo sapiens interferon-inducible
RNA-dependent protein kinase protein.
Length = 551
Score = 95.1 bits (226), Expect = 2e-19
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 2/153 (1%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGL 393
L +++F Q+ +G+ YIHS+ +IH D+KPSN+F+ + V++GDFGL L+
Sbjct: 390 LALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK---QVKIGDFGLVTSLKNDGKRT 446
Query: 392 -ALGTHMYAAPEQLDGQCNPKS-DMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAH 219
+ GT Y +PEQ+ Q K D+Y+LG+IL EL+ T E K TDLR G I
Sbjct: 447 RSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDI 506
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLEEL 120
K ++ KL+ +KP R +T+++L L
Sbjct: 507 FD---KKEKTLLQKLLSKKPEDRPNTSEILRTL 536
>M85294-1|AAA18253.1| 551|Homo sapiens P1/eIF-2a protein kinase
protein.
Length = 551
Score = 95.1 bits (226), Expect = 2e-19
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 2/153 (1%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGL 393
L +++F Q+ +G+ YIHS+ +IH D+KPSN+F+ + V++GDFGL L+
Sbjct: 390 LALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK---QVKIGDFGLVTSLKNDGKRT 446
Query: 392 -ALGTHMYAAPEQLDGQCNPKS-DMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAH 219
+ GT Y +PEQ+ Q K D+Y+LG+IL EL+ T E K TDLR G I
Sbjct: 447 RSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDI 506
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLEEL 120
K ++ KL+ +KP R +T+++L L
Sbjct: 507 FD---KKEKTLLQKLLSKKPEDRPNTSEILRTL 536
>M35663-1|AAA36409.1| 551|Homo sapiens protein ( Human p68 kinase
mRNA, complete cds. ).
Length = 551
Score = 95.1 bits (226), Expect = 2e-19
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 2/153 (1%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGL 393
L +++F Q+ +G+ YIHS+ +IH D+KPSN+F+ + V++GDFGL L+
Sbjct: 390 LALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK---QVKIGDFGLVTSLKNDGKRT 446
Query: 392 -ALGTHMYAAPEQLDGQCNPKS-DMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAH 219
+ GT Y +PEQ+ Q K D+Y+LG+IL EL+ T E K TDLR G I
Sbjct: 447 RSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDI 506
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLEEL 120
K ++ KL+ +KP R +T+++L L
Sbjct: 507 FD---KKEKTLLQKLLSKKPEDRPNTSEILRTL 536
>BC101475-1|AAI01476.1| 551|Homo sapiens eukaryotic translation
initiation factor 2-alpha kinase 2 protein.
Length = 551
Score = 95.1 bits (226), Expect = 2e-19
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 2/153 (1%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGL 393
L +++F Q+ +G+ YIHS+ +IH D+KPSN+F+ + V++GDFGL L+
Sbjct: 390 LALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK---QVKIGDFGLVTSLKNDGKRT 446
Query: 392 -ALGTHMYAAPEQLDGQCNPKS-DMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAH 219
+ GT Y +PEQ+ Q K D+Y+LG+IL EL+ T E K TDLR G I
Sbjct: 447 RSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDI 506
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLEEL 120
K ++ KL+ +KP R +T+++L L
Sbjct: 507 FD---KKEKTLLQKLLSKKPEDRPNTSEILRTL 536
>BC093676-1|AAH93676.1| 551|Homo sapiens eukaryotic translation
initiation factor 2-alpha kinase 2 protein.
Length = 551
Score = 95.1 bits (226), Expect = 2e-19
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 2/153 (1%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGL 393
L +++F Q+ +G+ YIHS+ +IH D+KPSN+F+ + V++GDFGL L+
Sbjct: 390 LALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK---QVKIGDFGLVTSLKNDGKRT 446
Query: 392 -ALGTHMYAAPEQLDGQCNPKS-DMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAH 219
+ GT Y +PEQ+ Q K D+Y+LG+IL EL+ T E K TDLR G I
Sbjct: 447 RSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDI 506
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLEEL 120
K ++ KL+ +KP R +T+++L L
Sbjct: 507 FD---KKEKTLLQKLLSKKPEDRPNTSEILRTL 536
>AY302136-1|AAP57628.1| 510|Homo sapiens interferon-inducible
double-stranded RNA-dependent protein kinase protein.
Length = 510
Score = 95.1 bits (226), Expect = 2e-19
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 2/153 (1%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGL 393
L +++F Q+ +G+ YIHS+ +IH D+KPSN+F+ + V++GDFGL L+
Sbjct: 349 LALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK---QVKIGDFGLVTSLKNDGKRT 405
Query: 392 -ALGTHMYAAPEQLDGQCNPKS-DMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAH 219
+ GT Y +PEQ+ Q K D+Y+LG+IL EL+ T E K TDLR G I
Sbjct: 406 RSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDI 465
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLEEL 120
K ++ KL+ +KP R +T+++L L
Sbjct: 466 FD---KKEKTLLQKLLSKKPEDRPNTSEILRTL 495
>AY228338-1|AAO38055.1| 551|Homo sapiens protein kinase,
interferon-inducible double stranded RNA dependent
protein.
Length = 551
Score = 95.1 bits (226), Expect = 2e-19
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 2/153 (1%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGL 393
L +++F Q+ +G+ YIHS+ +IH D+KPSN+F+ + V++GDFGL L+
Sbjct: 390 LALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK---QVKIGDFGLVTSLKNDGKRT 446
Query: 392 -ALGTHMYAAPEQLDGQCNPKS-DMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAH 219
+ GT Y +PEQ+ Q K D+Y+LG+IL EL+ T E K TDLR G I
Sbjct: 447 RSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDI 506
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLEEL 120
K ++ KL+ +KP R +T+++L L
Sbjct: 507 FD---KKEKTLLQKLLSKKPEDRPNTSEILRTL 536
>AC007899-1|AAY24317.1| 551|Homo sapiens unknown protein.
Length = 551
Score = 95.1 bits (226), Expect = 2e-19
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 2/153 (1%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGL 393
L +++F Q+ +G+ YIHS+ +IH D+KPSN+F+ + V++GDFGL L+
Sbjct: 390 LALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK---QVKIGDFGLVTSLKNDGKRT 446
Query: 392 -ALGTHMYAAPEQLDGQCNPKS-DMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAH 219
+ GT Y +PEQ+ Q K D+Y+LG+IL EL+ T E K TDLR G I
Sbjct: 447 RSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIISDI 506
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLEEL 120
K ++ KL+ +KP R +T+++L L
Sbjct: 507 FD---KKEKTLLQKLLSKKPEDRPNTSEILRTL 536
>AF167472-1|AAF13156.1| 551|Homo sapiens double stranded RNA
activated protein kinase protein.
Length = 551
Score = 92.7 bits (220), Expect = 1e-18
Identities = 56/153 (36%), Positives = 86/153 (56%), Gaps = 2/153 (1%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGL 393
L +++F Q+ +G+ YIHS+ +IH D+KPSN+F+ + V++GDFGL L+
Sbjct: 390 LALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK---QVKIGDFGLVTSLKNDGKRT 446
Query: 392 -ALGTHMYAAPEQLDGQCNPKS-DMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAH 219
+ GT Y +PEQ+ Q K D+Y+LG+IL EL+ T E K TDLR G I
Sbjct: 447 RSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGIIS-- 504
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLEEL 120
K ++ KL+ + P R +T+++L L
Sbjct: 505 -DIXDKKEETLLQKLLSKXPEDRPNTSEILRTL 536
>BC057805-1|AAH57805.1| 513|Homo sapiens EIF2AK2 protein protein.
Length = 513
Score = 86.6 bits (205), Expect = 8e-17
Identities = 48/117 (41%), Positives = 70/117 (59%), Gaps = 2/117 (1%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGL 393
L +++F Q+ +G+ YIHS+ +IH D+KPSN+F+ + V++GDFGL L+
Sbjct: 390 LALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK---QVKIGDFGLVTSLKNDGKRT 446
Query: 392 -ALGTHMYAAPEQLDGQCNPKS-DMYSLGIILLELVEPFVTDMERVKTITDLRKGQI 228
+ GT Y +PEQ+ Q K D+Y+LG+IL EL+ T E K TDLR G I
Sbjct: 447 RSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGII 503
>BC040851-1|AAH40851.1| 513|Homo sapiens EIF2AK2 protein protein.
Length = 513
Score = 86.6 bits (205), Expect = 8e-17
Identities = 48/117 (41%), Positives = 70/117 (59%), Gaps = 2/117 (1%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGL 393
L +++F Q+ +G+ YIHS+ +IH D+KPSN+F+ + V++GDFGL L+
Sbjct: 390 LALELFEQITKGVDYIHSKKLIHRDLKPSNIFLVDTK---QVKIGDFGLVTSLKNDGKRT 446
Query: 392 -ALGTHMYAAPEQLDGQCNPKS-DMYSLGIILLELVEPFVTDMERVKTITDLRKGQI 228
+ GT Y +PEQ+ Q K D+Y+LG+IL EL+ T E K TDLR G I
Sbjct: 447 RSKGTLRYMSPEQISSQDYGKEVDLYALGLILAELLHVCDTAFETSKFFTDLRDGII 503
>D87116-1|BAA13248.1| 347|Homo sapiens MAP kinase kinase 3b
protein.
Length = 347
Score = 73.7 bits (173), Expect = 6e-13
Identities = 54/188 (28%), Positives = 101/188 (53%), Gaps = 14/188 (7%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSR-GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS-H 402
D+L ++ +VR L ++HS+ +IH D+KPSNV + EG V++ DFG++ L S
Sbjct: 164 DILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLI-NKEGH--VKMCDFGISGYLVDSVA 220
Query: 401 SGLALGTHMYAAPEQLDGQCNP-----KSDMYSLGIILLELV------EPFVTDMERVKT 255
+ G Y APE+++ + N KSD++SLGI ++E+ E + T +++K
Sbjct: 221 KTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQ 280
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE-LKTLAENKDDTIRSL 78
+ + Q+PA + P+ + +++ P++R+ +L+E TL + K I +
Sbjct: 281 VVEEPSPQLPADRFS--PEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAF 338
Query: 77 REELAAKD 54
+E+ +D
Sbjct: 339 VKEILGED 346
>CR541793-1|CAG46592.1| 347|Homo sapiens MAP2K3 protein.
Length = 347
Score = 73.7 bits (173), Expect = 6e-13
Identities = 54/188 (28%), Positives = 101/188 (53%), Gaps = 14/188 (7%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSR-GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS-H 402
D+L ++ +VR L ++HS+ +IH D+KPSNV + EG V++ DFG++ L S
Sbjct: 164 DILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLI-NKEGH--VKMCDFGISGYLVDSVA 220
Query: 401 SGLALGTHMYAAPEQLDGQCNP-----KSDMYSLGIILLELV------EPFVTDMERVKT 255
+ G Y APE+++ + N KSD++SLGI ++E+ E + T +++K
Sbjct: 221 KTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQ 280
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE-LKTLAENKDDTIRSL 78
+ + Q+PA + P+ + +++ P++R+ +L+E TL + K I +
Sbjct: 281 VVEEPSPQLPADRFS--PEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAF 338
Query: 77 REELAAKD 54
+E+ +D
Sbjct: 339 VKEILGED 346
>CR536514-1|CAG38752.1| 347|Homo sapiens MAP2K3 protein.
Length = 347
Score = 73.7 bits (173), Expect = 6e-13
Identities = 54/188 (28%), Positives = 101/188 (53%), Gaps = 14/188 (7%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSR-GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS-H 402
D+L ++ +VR L ++HS+ +IH D+KPSNV + EG V++ DFG++ L S
Sbjct: 164 DILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLI-NKEGH--VKMCDFGISGYLVDSVA 220
Query: 401 SGLALGTHMYAAPEQLDGQCNP-----KSDMYSLGIILLELV------EPFVTDMERVKT 255
+ G Y APE+++ + N KSD++SLGI ++E+ E + T +++K
Sbjct: 221 KTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQ 280
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE-LKTLAENKDDTIRSL 78
+ + Q+PA + P+ + +++ P++R+ +L+E TL + K I +
Sbjct: 281 VVEEPSPQLPADRFS--PEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAF 338
Query: 77 REELAAKD 54
+E+ +D
Sbjct: 339 VKEILGED 346
>BC032478-1|AAH32478.1| 347|Homo sapiens mitogen-activated protein
kinase kinase 3 protein.
Length = 347
Score = 73.7 bits (173), Expect = 6e-13
Identities = 54/188 (28%), Positives = 101/188 (53%), Gaps = 14/188 (7%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSR-GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS-H 402
D+L ++ +VR L ++HS+ +IH D+KPSNV + EG V++ DFG++ L S
Sbjct: 164 DILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLI-NKEGH--VKMCDFGISGYLVDSVA 220
Query: 401 SGLALGTHMYAAPEQLDGQCNP-----KSDMYSLGIILLELV------EPFVTDMERVKT 255
+ G Y APE+++ + N KSD++SLGI ++E+ E + T +++K
Sbjct: 221 KTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQ 280
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE-LKTLAENKDDTIRSL 78
+ + Q+PA + P+ + +++ P++R+ +L+E TL + K I +
Sbjct: 281 VVEEPSPQLPADRFS--PEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAF 338
Query: 77 REELAAKD 54
+E+ +D
Sbjct: 339 VKEILGED 346
>AK223490-1|BAD97210.1| 347|Homo sapiens mitogen-activated protein
kinase kinase 3 isoform B variant protein.
Length = 347
Score = 73.7 bits (173), Expect = 6e-13
Identities = 54/188 (28%), Positives = 101/188 (53%), Gaps = 14/188 (7%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSR-GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS-H 402
D+L ++ +VR L ++HS+ +IH D+KPSNV + EG V++ DFG++ L S
Sbjct: 164 DILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLI-NKEGH--VKMCDFGISGYLVDSVA 220
Query: 401 SGLALGTHMYAAPEQLDGQCNP-----KSDMYSLGIILLELV------EPFVTDMERVKT 255
+ G Y APE+++ + N KSD++SLGI ++E+ E + T +++K
Sbjct: 221 KTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQ 280
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE-LKTLAENKDDTIRSL 78
+ + Q+PA + P+ + +++ P++R+ +L+E TL + K I +
Sbjct: 281 VVEEPSPQLPADRFS--PEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAF 338
Query: 77 REELAAKD 54
+E+ +D
Sbjct: 339 VKEILGED 346
>Z84469-2|CAI42732.1| 1790|Homo sapiens WNK lysine deficient protein
kinase 3 protein.
Length = 1790
Score = 73.3 bits (172), Expect = 8e-13
Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA ++ S + +GT
Sbjct: 256 QILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLMRTSFAKSVIGTP 313
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT-A 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 314 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKV 373
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
P++ II +++ S+RL LL A +DT LR ELA +DD
Sbjct: 374 TDPEVKEIIEGCIRQNKSERLSIRDLLNH----AFFAEDT--GLRVELAEEDD 420
>Z84469-1|CAI42733.1| 1743|Homo sapiens WNK lysine deficient protein
kinase 3 protein.
Length = 1743
Score = 73.3 bits (172), Expect = 8e-13
Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA ++ S + +GT
Sbjct: 256 QILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLMRTSFAKSVIGTP 313
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT-A 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 314 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKV 373
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
P++ II +++ S+RL LL A +DT LR ELA +DD
Sbjct: 374 TDPEVKEIIEGCIRQNKSERLSIRDLLNH----AFFAEDT--GLRVELAEEDD 420
>AY352048-1|AAR89465.1| 1800|Homo sapiens putative protein kinase
WNK3 protein.
Length = 1800
Score = 73.3 bits (172), Expect = 8e-13
Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA ++ S + +GT
Sbjct: 256 QILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLMRTSFAKSVIGTP 313
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT-A 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 314 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKV 373
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
P++ II +++ S+RL LL A +DT LR ELA +DD
Sbjct: 374 TDPEVKEIIEGCIRQNKSERLSIRDLLNH----AFFAEDT--GLRVELAEEDD 420
>AY082340-1|AAL99253.1| 1800|Homo sapiens putative protein kinase
WNK3 protein.
Length = 1800
Score = 73.3 bits (172), Expect = 8e-13
Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA ++ S + +GT
Sbjct: 256 QILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLMRTSFAKSVIGTP 313
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT-A 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 314 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKV 373
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
P++ II +++ S+RL LL A +DT LR ELA +DD
Sbjct: 374 TDPEVKEIIEGCIRQNKSERLSIRDLLNH----AFFAEDT--GLRVELAEEDD 420
>AL591766-2|CAI40707.1| 1790|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1790
Score = 73.3 bits (172), Expect = 8e-13
Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA ++ S + +GT
Sbjct: 256 QILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLMRTSFAKSVIGTP 313
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT-A 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 314 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKV 373
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
P++ II +++ S+RL LL A +DT LR ELA +DD
Sbjct: 374 TDPEVKEIIEGCIRQNKSERLSIRDLLNH----AFFAEDT--GLRVELAEEDD 420
>AL591766-1|CAI40708.1| 1743|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1743
Score = 73.3 bits (172), Expect = 8e-13
Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA ++ S + +GT
Sbjct: 256 QILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLMRTSFAKSVIGTP 313
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT-A 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 314 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKV 373
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
P++ II +++ S+RL LL A +DT LR ELA +DD
Sbjct: 374 TDPEVKEIIEGCIRQNKSERLSIRDLLNH----AFFAEDT--GLRVELAEEDD 420
>AL049793-2|CAI43128.1| 1790|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1790
Score = 73.3 bits (172), Expect = 8e-13
Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA ++ S + +GT
Sbjct: 256 QILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLMRTSFAKSVIGTP 313
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT-A 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 314 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKV 373
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
P++ II +++ S+RL LL A +DT LR ELA +DD
Sbjct: 374 TDPEVKEIIEGCIRQNKSERLSIRDLLNH----AFFAEDT--GLRVELAEEDD 420
>AL049793-1|CAI43129.1| 1743|Homo sapiens WNK lysine deficient
protein kinase 3 protein.
Length = 1743
Score = 73.3 bits (172), Expect = 8e-13
Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA ++ S + +GT
Sbjct: 256 QILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLMRTSFAKSVIGTP 313
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT-A 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 314 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKV 373
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
P++ II +++ S+RL LL A +DT LR ELA +DD
Sbjct: 374 TDPEVKEIIEGCIRQNKSERLSIRDLLNH----AFFAEDT--GLRVELAEEDD 420
>AJ409088-1|CAC32455.2| 1743|Homo sapiens protein kinase WNK3
protein.
Length = 1743
Score = 73.3 bits (172), Expect = 8e-13
Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 6/173 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA ++ S + +GT
Sbjct: 256 QILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLMRTSFAKSVIGTP 313
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT-A 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 314 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGIKPASFNKV 373
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
P++ II +++ S+RL LL A +DT LR ELA +DD
Sbjct: 374 TDPEVKEIIEGCIRQNKSERLSIRDLLNH----AFFAEDT--GLRVELAEEDD 420
>M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein.
Length = 766
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/181 (32%), Positives = 100/181 (55%), Gaps = 15/181 (8%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ---SHS 399
LID+ Q +G+ Y+H++ IIH D+K +N+F+ HE L V++GDFGLA + SH
Sbjct: 553 LIDIARQTAQGMDYLHAKSIIHRDLKSNNIFL--HE-DLTVKIGDFGLATVKSRWSGSHQ 609
Query: 398 GLAL-GTHMYAAPEQLDGQ-CNP---KSDMYSLGIILLELVE---PFVTDMERVKTITDL 243
L G+ ++ APE + Q NP +SD+Y+ GI+L EL+ P+ R + I +
Sbjct: 610 FEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMV 669
Query: 242 RKGQIPAHLT---ANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLR 75
+G + L+ +N PK + ++ + +++K +R Q+L ++ LA + RS
Sbjct: 670 GRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSAS 729
Query: 74 E 72
E
Sbjct: 730 E 730
>M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein.
Length = 328
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/181 (32%), Positives = 100/181 (55%), Gaps = 15/181 (8%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ---SHS 399
LID+ Q +G+ Y+H++ IIH D+K +N+F+ HE L V++GDFGLA + SH
Sbjct: 115 LIDIARQTAQGMDYLHAKSIIHRDLKSNNIFL--HE-DLTVKIGDFGLATVKSRWSGSHQ 171
Query: 398 GLAL-GTHMYAAPEQLDGQ-CNP---KSDMYSLGIILLELVE---PFVTDMERVKTITDL 243
L G+ ++ APE + Q NP +SD+Y+ GI+L EL+ P+ R + I +
Sbjct: 172 FEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMV 231
Query: 242 RKGQIPAHLT---ANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLR 75
+G + L+ +N PK + ++ + +++K +R Q+L ++ LA + RS
Sbjct: 232 GRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSAS 291
Query: 74 E 72
E
Sbjct: 292 E 292
>BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/181 (32%), Positives = 100/181 (55%), Gaps = 15/181 (8%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ---SHS 399
LID+ Q +G+ Y+H++ IIH D+K +N+F+ HE L V++GDFGLA + SH
Sbjct: 553 LIDIARQTAQGMDYLHAKSIIHRDLKSNNIFL--HE-DLTVKIGDFGLATVKSRWSGSHQ 609
Query: 398 GLAL-GTHMYAAPEQLDGQ-CNP---KSDMYSLGIILLELVE---PFVTDMERVKTITDL 243
L G+ ++ APE + Q NP +SD+Y+ GI+L EL+ P+ R + I +
Sbjct: 610 FEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMV 669
Query: 242 RKGQIPAHLT---ANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLR 75
+G + L+ +N PK + ++ + +++K +R Q+L ++ LA + RS
Sbjct: 670 GRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSAS 729
Query: 74 E 72
E
Sbjct: 730 E 730
>BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma viral
oncogene homolog B1 protein.
Length = 766
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/181 (32%), Positives = 100/181 (55%), Gaps = 15/181 (8%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ---SHS 399
LID+ Q +G+ Y+H++ IIH D+K +N+F+ HE L V++GDFGLA + SH
Sbjct: 553 LIDIARQTAQGMDYLHAKSIIHRDLKSNNIFL--HE-DLTVKIGDFGLATVKSRWSGSHQ 609
Query: 398 GLAL-GTHMYAAPEQLDGQ-CNP---KSDMYSLGIILLELVE---PFVTDMERVKTITDL 243
L G+ ++ APE + Q NP +SD+Y+ GI+L EL+ P+ R + I +
Sbjct: 610 FEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMV 669
Query: 242 RKGQIPAHLT---ANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLR 75
+G + L+ +N PK + ++ + +++K +R Q+L ++ LA + RS
Sbjct: 670 GRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSAS 729
Query: 74 E 72
E
Sbjct: 730 E 730
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/181 (32%), Positives = 100/181 (55%), Gaps = 15/181 (8%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ---SHS 399
LID+ Q +G+ Y+H++ IIH D+K +N+F+ HE L V++GDFGLA + SH
Sbjct: 1279 LIDIARQTAQGMDYLHAKSIIHRDLKSNNIFL--HE-DLTVKIGDFGLATVKSRWSGSHQ 1335
Query: 398 GLAL-GTHMYAAPEQLDGQ-CNP---KSDMYSLGIILLELVE---PFVTDMERVKTITDL 243
L G+ ++ APE + Q NP +SD+Y+ GI+L EL+ P+ R + I +
Sbjct: 1336 FEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMV 1395
Query: 242 RKGQIPAHLT---ANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLR 75
+G + L+ +N PK + ++ + +++K +R Q+L ++ LA + RS
Sbjct: 1396 GRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSAS 1455
Query: 74 E 72
E
Sbjct: 1456 E 1456
>AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3
protein.
Length = 651
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/181 (32%), Positives = 100/181 (55%), Gaps = 15/181 (8%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ---SHS 399
LID+ Q +G+ Y+H++ IIH D+K +N+F+ HE L V++GDFGLA + SH
Sbjct: 438 LIDIARQTAQGMDYLHAKSIIHRDLKSNNIFL--HE-DLTVKIGDFGLATVKSRWSGSHQ 494
Query: 398 GLAL-GTHMYAAPEQLDGQ-CNP---KSDMYSLGIILLELVE---PFVTDMERVKTITDL 243
L G+ ++ APE + Q NP +SD+Y+ GI+L EL+ P+ R + I +
Sbjct: 495 FEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMV 554
Query: 242 RKGQIPAHLT---ANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLR 75
+G + L+ +N PK + ++ + +++K +R Q+L ++ LA + RS
Sbjct: 555 GRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSAS 614
Query: 74 E 72
E
Sbjct: 615 E 615
>U66840-1|AAB40653.1| 352|Homo sapiens MAP kinase 3c protein.
Length = 352
Score = 72.1 bits (169), Expect = 2e-12
Identities = 53/188 (28%), Positives = 101/188 (53%), Gaps = 14/188 (7%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSR-GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS-H 402
D+L ++ +VR L ++HS+ +IH D+KPSNV + EG V++ DFG++ L S
Sbjct: 169 DILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLI-NKEGH--VKMCDFGISGYLVDSVA 225
Query: 401 SGLALGTHMYAAPEQLDGQCNP-----KSDMYSLGIILLELV------EPFVTDMERVKT 255
+ G Y APE+++ + N KSD++SLGI ++E+ E + T +++K
Sbjct: 226 KTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQ 285
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE-LKTLAENKDDTIRSL 78
+ + Q+PA + P+ + +++ P++R+ +L+E TL + K I +
Sbjct: 286 VVEEPSPQLPADRFS--PEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAF 343
Query: 77 REELAAKD 54
+++ +D
Sbjct: 344 VKKILGED 351
>U66839-1|AAB40652.1| 347|Homo sapiens MAP kinase 3b protein.
Length = 347
Score = 72.1 bits (169), Expect = 2e-12
Identities = 53/188 (28%), Positives = 101/188 (53%), Gaps = 14/188 (7%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSR-GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS-H 402
D+L ++ +VR L ++HS+ +IH D+KPSNV + EG V++ DFG++ L S
Sbjct: 164 DILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLI-NKEGH--VKMCDFGISGYLVDSVA 220
Query: 401 SGLALGTHMYAAPEQLDGQCNP-----KSDMYSLGIILLELV------EPFVTDMERVKT 255
+ G Y APE+++ + N KSD++SLGI ++E+ E + T +++K
Sbjct: 221 KTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQ 280
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE-LKTLAENKDDTIRSL 78
+ + Q+PA + P+ + +++ P++R+ +L+E TL + K I +
Sbjct: 281 VVEEPSPQLPADRFS--PEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAF 338
Query: 77 REELAAKD 54
+++ +D
Sbjct: 339 VKKILGED 346
>L36719-1|AAC41718.1| 318|Homo sapiens MAP kinase kinase 3 protein.
Length = 318
Score = 72.1 bits (169), Expect = 2e-12
Identities = 53/188 (28%), Positives = 101/188 (53%), Gaps = 14/188 (7%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSR-GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS-H 402
D+L ++ +VR L ++HS+ +IH D+KPSNV + EG V++ DFG++ L S
Sbjct: 135 DILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLI-NKEGH--VKMCDFGISGYLVDSVA 191
Query: 401 SGLALGTHMYAAPEQLDGQCNP-----KSDMYSLGIILLELV------EPFVTDMERVKT 255
+ G Y APE+++ + N KSD++SLGI ++E+ E + T +++K
Sbjct: 192 KTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQ 251
Query: 254 ITDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE-LKTLAENKDDTIRSL 78
+ + Q+PA + P+ + +++ P++R+ +L+E TL + K I +
Sbjct: 252 VVEEPSPQLPADRFS--PEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAF 309
Query: 77 REELAAKD 54
+++ +D
Sbjct: 310 VKKILGED 317
>X69117-1|CAA48870.1| 688|Homo sapiens beta-adrenergic kinase 2
protein.
Length = 688
Score = 70.1 bits (164), Expect = 7e-12
Identities = 43/142 (30%), Positives = 75/142 (52%), Gaps = 6/142 (4%)
Frame = -1
Query: 554 TQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHM 375
T+++ GL ++H+R +++ D+KP+N+ + H ++ D GLAC + ++GTH
Sbjct: 299 TEIILGLEHVHNRFVVYRDLKPANILLDEHGH---ARISDLGLACDFSKKKPHASVGTHG 355
Query: 374 YAAPEQLD-GQC-NPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQIPAHLTA 210
Y APE L G + +D +SLG +L +L+ PF + K D + L
Sbjct: 356 YMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPD 415
Query: 209 NY-PKIAHIIGKLVQRKPSKRL 147
+ P++ ++ L+QR SKRL
Sbjct: 416 TFSPELKSLLEGLLQRDVSKRL 437
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 70.1 bits (164), Expect = 7e-12
Identities = 38/97 (39%), Positives = 59/97 (60%), Gaps = 3/97 (3%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSH-- 402
D ++ F Q+ GL +IH R I+H DIK N+F++ + G++ +LGDFG+A L S
Sbjct: 103 DQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLS--KNGMVAKLGDFGIARVLNNSMEL 160
Query: 401 SGLALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL 294
+ +GT Y +PE + N K+D++SLG +L EL
Sbjct: 161 ARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYEL 197
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 70.1 bits (164), Expect = 7e-12
Identities = 38/97 (39%), Positives = 59/97 (60%), Gaps = 3/97 (3%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSH-- 402
D ++ F Q+ GL +IH R I+H DIK N+F++ + G++ +LGDFG+A L S
Sbjct: 103 DQILGWFVQISLGLKHIHDRKILHRDIKAQNIFLS--KNGMVAKLGDFGIARVLNNSMEL 160
Query: 401 SGLALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL 294
+ +GT Y +PE + N K+D++SLG +L EL
Sbjct: 161 ARTCIGTPYYLSPEICQNKPYNNKTDIWSLGCVLYEL 197
>L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein.
Length = 421
Score = 69.7 bits (163), Expect = 1e-11
Identities = 62/212 (29%), Positives = 104/212 (49%), Gaps = 16/212 (7%)
Frame = -1
Query: 659 DDFTLPLHVCESPIEAKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNV 480
D+ + CE K + + + LID+ Q +G+ Y+H++ IIH D+K +N+
Sbjct: 188 DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNI 247
Query: 479 FVAPHEGGLLVQLGDFGLACPLQQSHSG-----LALGTHMYAAPEQLDGQCNP----KSD 327
F+ HE GL V++GDFGLA ++ SG G+ ++ APE + Q N +SD
Sbjct: 248 FL--HE-GLTVKIGDFGLA-TVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSD 303
Query: 326 MYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT---ANYPK-IAHIIGKLVQ 168
+YS GI+L EL+ P+ R + I + +G L+ N PK + ++ V+
Sbjct: 304 VYSYGIVLYELITGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVK 363
Query: 167 RKPSKRLDTAQLLEELKTLAENKDDTIRSLRE 72
+ +R Q+L ++ L + RS E
Sbjct: 364 KVKEERPLFPQILSSIELLQHSLPKINRSASE 395
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 69.7 bits (163), Expect = 1e-11
Identities = 51/156 (32%), Positives = 78/156 (50%), Gaps = 8/156 (5%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHS- 399
DL F Q+V + Y H ++H D+KP NV +G LV+L DFG + Q
Sbjct: 115 DLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQG--LVKLTDFGFSNKFQPGKKL 172
Query: 398 GLALGTHMYAAPEQL--DGQCNPKSDMYSLGIILLELV---EPF--VTDMERVKTITDLR 240
+ G+ Y+APE L D P D++SLG+IL LV PF D E + I D
Sbjct: 173 TTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDC- 231
Query: 239 KGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQL 132
K +P+H++ + +I +++QR P +R ++
Sbjct: 232 KYTVPSHVS---KECKDLITRMLQRDPKRRASLEEI 264
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 69.3 bits (162), Expect = 1e-11
Identities = 51/150 (34%), Positives = 76/150 (50%), Gaps = 8/150 (5%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHS- 399
DL F Q+V + Y H ++H D+KP NV +G LV+L DFG + Q
Sbjct: 114 DLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQG--LVKLTDFGFSNKFQPGKKL 171
Query: 398 GLALGTHMYAAPEQL--DGQCNPKSDMYSLGIILLELV---EPF--VTDMERVKTITDLR 240
+ G+ Y+APE L D P D++SLG+IL LV PF D E + I D
Sbjct: 172 TTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDC- 230
Query: 239 KGQIPAHLTANYPKIAHIIGKLVQRKPSKR 150
K +P+H++ + +I +++QR P +R
Sbjct: 231 KYTVPSHVS---KECKDLITRMLQRDPKRR 257
>BC032784-1|AAH32784.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II delta protein.
Length = 478
Score = 69.3 bits (162), Expect = 1e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++ H GI+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K DM++ G+IL L+ P D ++ + ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ +I K++ P+KR+ ++ L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 298 RKLKGAILTTMLATRNFSA 316
>AY987011-1|AAX88806.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
protein.
Length = 489
Score = 69.3 bits (162), Expect = 1e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++ H GI+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K DM++ G+IL L+ P D ++ + ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ +I K++ P+KR+ ++ L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKDLINKMLTINPAKRITASEALKHPWTCQRSTVASMMHRQETVDCLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 298 RKLKGAILTTMLATRNFSA 316
>AL022329-1|CAB45657.1| 688|Homo sapiens adrenergic, beta, receptor
kinase 2 protein.
Length = 688
Score = 69.3 bits (162), Expect = 1e-11
Identities = 43/142 (30%), Positives = 75/142 (52%), Gaps = 6/142 (4%)
Frame = -1
Query: 554 TQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHM 375
T+++ GL ++H+R +++ D+KP+N+ + H ++ D GLAC + ++GTH
Sbjct: 299 TEIILGLEHMHNRFVVYRDLKPANILLDEHGH---ARISDLGLACDFSKKKPHASVGTHG 355
Query: 374 YAAPEQLD-GQC-NPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQIPAHLTA 210
Y APE L G + +D +SLG +L +L+ PF + K D + L
Sbjct: 356 YMAPEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPD 415
Query: 209 NY-PKIAHIIGKLVQRKPSKRL 147
+ P++ ++ L+QR SKRL
Sbjct: 416 TFSPELKSLLEGLLQRDVSKRL 437
>AK096052-1|BAC04688.1| 663|Homo sapiens protein ( Homo sapiens
cDNA FLJ38733 fis, clone KIDNE2010762, moderately
similar to Rattus norvegicus protein kinase WNK1 (WNK1)
mRNA. ).
Length = 663
Score = 69.3 bits (162), Expect = 1e-11
Identities = 53/183 (28%), Positives = 88/183 (48%), Gaps = 7/183 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSR--GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q++RGLH++HSR I+H D+K NVF+ G V++GD GLA + S + +GT
Sbjct: 55 QILRGLHFLHSRVPPILHRDLKCDNVFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 112
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIP-AHLTA 210
+ APE + + + D+Y+ G+ +LE+ P+ + + G+ P +
Sbjct: 113 EFMAPEMYEEKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGRKPNSFHKV 172
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD-EIAKLK 33
P++ II ++ ++R LL E R + ELA +DD E LK
Sbjct: 173 KIPEVKEIIEGCIRTDKNERFTIQDLLAHAFFREE------RGVHVELAEEDDGEKPGLK 226
Query: 32 MML 24
+ L
Sbjct: 227 LWL 229
>AJ316534-1|CAC48387.1| 1231|Homo sapiens serine/threonine protein
kinase protein.
Length = 1231
Score = 69.3 bits (162), Expect = 1e-11
Identities = 53/183 (28%), Positives = 88/183 (48%), Gaps = 7/183 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSR--GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q++RGLH++HSR I+H D+K NVF+ G V++GD GLA + S + +GT
Sbjct: 271 QILRGLHFLHSRVPPILHRDLKCDNVFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 328
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIP-AHLTA 210
+ APE + + + D+Y+ G+ +LE+ P+ + + G+ P +
Sbjct: 329 EFMAPEMYEEKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGRKPNSFHKV 388
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD-EIAKLK 33
P++ II ++ ++R LL E R + ELA +DD E LK
Sbjct: 389 KIPEVKEIIEGCIRTDKNERFTIQDLLAHAFFREE------RGVHVELAEEDDGEKPGLK 442
Query: 32 MML 24
+ L
Sbjct: 443 LWL 445
>AF390018-1|AAK91995.1| 1243|Homo sapiens putative protein kinase
WNK4 protein.
Length = 1243
Score = 69.3 bits (162), Expect = 1e-11
Identities = 53/183 (28%), Positives = 88/183 (48%), Gaps = 7/183 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSR--GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q++RGLH++HSR I+H D+K NVF+ G V++GD GLA + S + +GT
Sbjct: 283 QILRGLHFLHSRVPPILHRDLKCDNVFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 340
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIP-AHLTA 210
+ APE + + + D+Y+ G+ +LE+ P+ + + G+ P +
Sbjct: 341 EFMAPEMYEEKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGRKPNSFHKV 400
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD-EIAKLK 33
P++ II ++ ++R LL E R + ELA +DD E LK
Sbjct: 401 KIPEVKEIIEGCIRTDKNERFTIQDLLAHAFFREE------RGVHVELAEEDDGEKPGLK 454
Query: 32 MML 24
+ L
Sbjct: 455 LWL 457
>AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional
calcium/calmodulin-dependent protein kinase II delta2
isoform protein.
Length = 499
Score = 69.3 bits (162), Expect = 1e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++ H GI+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K DM++ G+IL L+ P D ++ + ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ +I K++ P+KR+ ++ L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 298 RKLKGAILTTMLATRNFSA 316
>AB209288-1|BAD92525.1| 522|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
isoform 1 variant protein.
Length = 522
Score = 69.3 bits (162), Expect = 1e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++ H GI+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 149 QILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 207
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K DM++ G+IL L+ P D ++ + ++ G P+
Sbjct: 208 PGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 267
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ +I K++ P+KR+ ++ L+ + T+A ++ +T+ L++ A
Sbjct: 268 WDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNAR 327
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 328 RKLKGAILTTMLATRNFSA 346
>X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for raf
oncogene. ).
Length = 648
Score = 68.9 bits (161), Expect = 2e-11
Identities = 62/212 (29%), Positives = 104/212 (49%), Gaps = 16/212 (7%)
Frame = -1
Query: 659 DDFTLPLHVCESPIEAKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNV 480
D+ + CE K + + + LID+ Q +G+ Y+H++ IIH D+K +N+
Sbjct: 415 DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNI 474
Query: 479 FVAPHEGGLLVQLGDFGLACPLQQSHSG-----LALGTHMYAAPEQLDGQCNP----KSD 327
F+ HE GL V++GDFGLA ++ SG G+ ++ APE + Q N +SD
Sbjct: 475 FL--HE-GLTVKIGDFGLA-TVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSD 530
Query: 326 MYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT---ANYPK-IAHIIGKLVQ 168
+YS GI+L EL+ P+ R + I + +G L+ N PK + ++ V+
Sbjct: 531 VYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVK 590
Query: 167 RKPSKRLDTAQLLEELKTLAENKDDTIRSLRE 72
+ +R Q+L ++ L + RS E
Sbjct: 591 KVKEERPLFPQILSSIELLQHSLPKINRSASE 622
>BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 68.9 bits (161), Expect = 2e-11
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 107 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 162
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
FG+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 163 FGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 222
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 223 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 280
Query: 92 T 90
T
Sbjct: 281 T 281
>BC151221-1|AAI51222.1| 1235|Homo sapiens TAO kinase 2 protein.
Length = 1235
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/163 (30%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH D+K N+ ++ E G LV+LGDFG A + ++S +GT + A
Sbjct: 136 LQGLAYLHSHNMIHRDVKAGNILLS--EPG-LVKLGDFGSASIMAPANS--FVGTPYWTA 190
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + ++
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHW 250
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSL 78
+ + + +Q+ P R + LL+ L E I L
Sbjct: 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDL 293
>BC142663-1|AAI42664.1| 1235|Homo sapiens TAO kinase 2 protein.
Length = 1235
Score = 68.9 bits (161), Expect = 2e-11
Identities = 49/163 (30%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH D+K N+ ++ E G LV+LGDFG A + ++S +GT + A
Sbjct: 136 LQGLAYLHSHNMIHRDVKAGNILLS--EPG-LVKLGDFGSASIMAPANS--FVGTPYWTA 190
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + ++
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHW 250
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSL 78
+ + + +Q+ P R + LL+ L E I L
Sbjct: 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDL 293
>BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 68.9 bits (161), Expect = 2e-11
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 107 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 162
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
FG+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 163 FGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 222
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 223 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 280
Query: 92 T 90
T
Sbjct: 281 T 281
>BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 68.9 bits (161), Expect = 2e-11
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 107 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 162
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
FG+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 163 FGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 222
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 223 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 280
Query: 92 T 90
T
Sbjct: 281 T 281
>BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 68.9 bits (161), Expect = 2e-11
Identities = 62/212 (29%), Positives = 104/212 (49%), Gaps = 16/212 (7%)
Frame = -1
Query: 659 DDFTLPLHVCESPIEAKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNV 480
D+ + CE K + + + LID+ Q +G+ Y+H++ IIH D+K +N+
Sbjct: 415 DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNI 474
Query: 479 FVAPHEGGLLVQLGDFGLACPLQQSHSG-----LALGTHMYAAPEQLDGQCNP----KSD 327
F+ HE GL V++GDFGLA ++ SG G+ ++ APE + Q N +SD
Sbjct: 475 FL--HE-GLTVKIGDFGLA-TVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSD 530
Query: 326 MYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT---ANYPK-IAHIIGKLVQ 168
+YS GI+L EL+ P+ R + I + +G L+ N PK + ++ V+
Sbjct: 531 VYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVK 590
Query: 167 RKPSKRLDTAQLLEELKTLAENKDDTIRSLRE 72
+ +R Q+L ++ L + RS E
Sbjct: 591 KVKEERPLFPQILSSIELLQHSLPKINRSASE 622
>AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 68.9 bits (161), Expect = 2e-11
Identities = 62/212 (29%), Positives = 104/212 (49%), Gaps = 16/212 (7%)
Frame = -1
Query: 659 DDFTLPLHVCESPIEAKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNV 480
D+ + CE K + + + LID+ Q +G+ Y+H++ IIH D+K +N+
Sbjct: 415 DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNI 474
Query: 479 FVAPHEGGLLVQLGDFGLACPLQQSHSG-----LALGTHMYAAPEQLDGQCNP----KSD 327
F+ HE GL V++GDFGLA ++ SG G+ ++ APE + Q N +SD
Sbjct: 475 FL--HE-GLTVKIGDFGLA-TVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSD 530
Query: 326 MYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHLT---ANYPK-IAHIIGKLVQ 168
+YS GI+L EL+ P+ R + I + +G L+ N PK + ++ V+
Sbjct: 531 VYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVK 590
Query: 167 RKPSKRLDTAQLLEELKTLAENKDDTIRSLRE 72
+ +R Q+L ++ L + RS E
Sbjct: 591 KVKEERPLFPQILSSIELLQHSLPKINRSASE 622
>AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 68.9 bits (161), Expect = 2e-11
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 107 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 162
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
FG+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 163 FGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 222
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 223 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 280
Query: 92 T 90
T
Sbjct: 281 T 281
>AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 68.9 bits (161), Expect = 2e-11
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 119 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 174
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
FG+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 175 FGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 234
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 235 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 292
Query: 92 T 90
T
Sbjct: 293 T 293
>AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 68.9 bits (161), Expect = 2e-11
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 24 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 79
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
FG+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 80 FGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 139
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 140 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 197
Query: 92 T 90
T
Sbjct: 198 T 198
>AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 68.9 bits (161), Expect = 2e-11
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 107 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 162
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
FG+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 163 FGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 222
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 223 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 280
Query: 92 T 90
T
Sbjct: 281 T 281
>AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 68.9 bits (161), Expect = 2e-11
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 119 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 174
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
FG+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 175 FGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 234
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 235 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 292
Query: 92 T 90
T
Sbjct: 293 T 293
>AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 68.9 bits (161), Expect = 2e-11
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 24 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 79
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
FG+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 80 FGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 139
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 140 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 197
Query: 92 T 90
T
Sbjct: 198 T 198
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 68.9 bits (161), Expect = 2e-11
Identities = 51/156 (32%), Positives = 78/156 (50%), Gaps = 8/156 (5%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHS- 399
DL F Q+V + Y H ++H D+KP NV +G LV+L DFG + Q
Sbjct: 114 DLPKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQG--LVKLTDFGFSNKFQPGKKL 171
Query: 398 GLALGTHMYAAPEQL--DGQCNPKSDMYSLGIILLELV---EPF--VTDMERVKTITDLR 240
+ G+ Y+APE L D P D++SLG+IL LV PF D E + I D
Sbjct: 172 TTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDC- 230
Query: 239 KGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQL 132
K +P+H++ + +I +++QR P +R ++
Sbjct: 231 KYTVPSHVS---KECKDLITRMLQRDPKRRASLEEI 263
>AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-like
protein kinase 3 protein.
Length = 443
Score = 68.9 bits (161), Expect = 2e-11
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 119 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 174
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
FG+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 175 FGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 234
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 235 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 292
Query: 92 T 90
T
Sbjct: 293 T 293
>AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3
protein.
Length = 431
Score = 68.9 bits (161), Expect = 2e-11
Identities = 54/181 (29%), Positives = 91/181 (50%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 107 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 162
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
FG+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 163 FGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 222
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 223 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 280
Query: 92 T 90
T
Sbjct: 281 T 281
>BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein.
Length = 1189
Score = 68.5 bits (160), Expect = 2e-11
Identities = 48/157 (30%), Positives = 79/157 (50%), Gaps = 6/157 (3%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS--H 402
D ++D F Q+ L ++H R I+H DIK N+F+ +G VQLGDFG+A L +
Sbjct: 103 DQILDWFVQICLALKHVHDRKILHRDIKSQNIFLT-KDG--TVQLGDFGIARVLNSTVEL 159
Query: 401 SGLALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKG 234
+ +GT Y +PE + + N KSD+++LG +L EL F + + +
Sbjct: 160 ARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGS 219
Query: 233 QIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
P L +Y + ++ +L +R P R +LE+
Sbjct: 220 FPPVSLHYSY-DLRSLVSQLFKRNPRDRPSVNSILEK 255
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 68.5 bits (160), Expect = 2e-11
Identities = 33/96 (34%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL-QQSHS 399
+ ++ F Q++ LH++H+ I+H D+K N+ + H ++V++GDFG++ L +S +
Sbjct: 103 ETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHR--MVVKIGDFGISKILSSKSKA 160
Query: 398 GLALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL 294
+GT Y +PE +G+ N KSD+++LG +L EL
Sbjct: 161 YTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYEL 196
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 68.5 bits (160), Expect = 2e-11
Identities = 33/96 (34%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL-QQSHS 399
+ ++ F Q++ LH++H+ I+H D+K N+ + H ++V++GDFG++ L +S +
Sbjct: 103 ETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHR--MVVKIGDFGISKILSSKSKA 160
Query: 398 GLALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL 294
+GT Y +PE +G+ N KSD+++LG +L EL
Sbjct: 161 YTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYEL 196
>BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein.
Length = 1426
Score = 68.5 bits (160), Expect = 2e-11
Identities = 49/163 (30%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH D+K N+ ++ E G LV+LGDFG A + ++S +GT + A
Sbjct: 320 LQGLAYLHSHNMIHRDVKAGNILLS--EPG-LVKLGDFGSASIMAPANS--FVGTPYWMA 374
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + ++
Sbjct: 375 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHW 434
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSL 78
+ + + +Q+ P R + LL+ L E I L
Sbjct: 435 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDL 477
>BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein.
Length = 560
Score = 68.5 bits (160), Expect = 2e-11
Identities = 49/163 (30%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH D+K N+ ++ E G LV+LGDFG A + ++S +GT + A
Sbjct: 136 LQGLAYLHSHNMIHRDVKAGNILLS--EPG-LVKLGDFGSASIMAPANS--FVGTPYWMA 190
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + ++
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHW 250
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSL 78
+ + + +Q+ P R + LL+ L E I L
Sbjct: 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDL 293
>BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for
IMAGE:3878048) protein.
Length = 762
Score = 68.5 bits (160), Expect = 2e-11
Identities = 49/163 (30%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH D+K N+ ++ E G LV+LGDFG A + ++S +GT + A
Sbjct: 136 LQGLAYLHSHNMIHRDVKAGNILLS--EPG-LVKLGDFGSASIMAPANS--FVGTPYWMA 190
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + ++
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHW 250
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSL 78
+ + + +Q+ P R + LL+ L E I L
Sbjct: 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDL 293
>BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for
IMAGE:4063881) protein.
Length = 403
Score = 68.5 bits (160), Expect = 2e-11
Identities = 48/157 (30%), Positives = 79/157 (50%), Gaps = 6/157 (3%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS--H 402
D ++D F Q+ L ++H R I+H DIK N+F+ +G VQLGDFG+A L +
Sbjct: 103 DQILDWFVQICLALKHVHDRKILHRDIKSQNIFLT-KDG--TVQLGDFGIARVLNSTVEL 159
Query: 401 SGLALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKG 234
+ +GT Y +PE + + N KSD+++LG +L EL F + + +
Sbjct: 160 ARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGS 219
Query: 233 QIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
P L +Y + ++ +L +R P R +LE+
Sbjct: 220 FPPVSLHYSY-DLRSLVSQLFKRNPRDRPSVNSILEK 255
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 68.5 bits (160), Expect = 2e-11
Identities = 33/96 (34%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL-QQSHS 399
+ ++ F Q++ LH++H+ I+H D+K N+ + H ++V++GDFG++ L +S +
Sbjct: 103 ETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHR--MVVKIGDFGISKILSSKSKA 160
Query: 398 GLALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL 294
+GT Y +PE +G+ N KSD+++LG +L EL
Sbjct: 161 YTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYEL 196
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 68.5 bits (160), Expect = 2e-11
Identities = 33/96 (34%), Positives = 61/96 (63%), Gaps = 2/96 (2%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL-QQSHS 399
+ ++ F Q++ LH++H+ I+H D+K N+ + H ++V++GDFG++ L +S +
Sbjct: 103 ETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHR--MVVKIGDFGISKILSSKSKA 160
Query: 398 GLALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL 294
+GT Y +PE +G+ N KSD+++LG +L EL
Sbjct: 161 YTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYEL 196
>AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein.
Length = 1049
Score = 68.5 bits (160), Expect = 2e-11
Identities = 49/163 (30%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH D+K N+ ++ E G LV+LGDFG A + ++S +GT + A
Sbjct: 136 LQGLAYLHSHNMIHRDVKAGNILLS--EPG-LVKLGDFGSASIMAPANS--FVGTPYWMA 190
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + ++
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHW 250
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSL 78
+ + + +Q+ P R + LL+ L E I L
Sbjct: 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDL 293
>AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived
STE20-like kinase PSK protein.
Length = 1235
Score = 68.5 bits (160), Expect = 2e-11
Identities = 49/163 (30%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH D+K N+ ++ E G LV+LGDFG A + ++S +GT + A
Sbjct: 136 LQGLAYLHSHNMIHRDVKAGNILLS--EPG-LVKLGDFGSASIMAPANS--FVGTPYWMA 190
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + ++
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHW 250
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSL 78
+ + + +Q+ P R + LL+ L E I L
Sbjct: 251 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDL 293
>AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein.
Length = 1265
Score = 68.5 bits (160), Expect = 2e-11
Identities = 48/157 (30%), Positives = 79/157 (50%), Gaps = 6/157 (3%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS--H 402
D ++D F Q+ L ++H R I+H DIK N+F+ +G VQLGDFG+A L +
Sbjct: 110 DQILDWFVQICLALKHVHDRKILHRDIKSQNIFLT-KDG--TVQLGDFGIARVLNSTVEL 166
Query: 401 SGLALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKG 234
+ +GT Y +PE + + N KSD+++LG +L EL F + + +
Sbjct: 167 ARTCIGTPYYLSPEICENKPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGS 226
Query: 233 QIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
P L +Y + ++ +L +R P R +LE+
Sbjct: 227 FPPVSLHYSY-DLRSLVSQLFKRNPRDRPSVNSILEK 262
>AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein.
Length = 1064
Score = 68.5 bits (160), Expect = 2e-11
Identities = 49/163 (30%), Positives = 86/163 (52%), Gaps = 7/163 (4%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH D+K N+ ++ E G LV+LGDFG A + ++S +GT + A
Sbjct: 151 LQGLAYLHSHNMIHRDVKAGNILLS--EPG-LVKLGDFGSASIMAPANS--FVGTPYWMA 205
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + ++
Sbjct: 206 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHW 265
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSL 78
+ + + +Q+ P R + LL+ L E I L
Sbjct: 266 SEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDL 308
>Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein.
Length = 459
Score = 68.1 bits (159), Expect = 3e-11
Identities = 51/156 (32%), Positives = 86/156 (55%), Gaps = 7/156 (4%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ--QSH 402
D++++ FTQ+ G+++IH + ++H DIK N+F+ + G V+LGDFG A L +
Sbjct: 55 DMILNWFTQMCLGVNHIHKKRVLHRDIKSKNIFLT--QNG-KVKLGDFGSARLLSNPMAF 111
Query: 401 SGLALGTHMYAAPEQLDG-QCNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKG 234
+ +GT Y PE + N KSD++SLG IL EL PF + + I + +G
Sbjct: 112 ACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWK-NLILKVCQG 170
Query: 233 QIPAHLTANYP-KIAHIIGKLVQRKPSKRLDTAQLL 129
I + L ++Y ++ ++ ++ +R PS R LL
Sbjct: 171 CI-SPLPSHYSYELQFLVKQMFKRNPSHRPSATTLL 205
>L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine
kinase protein.
Length = 841
Score = 68.1 bits (159), Expect = 3e-11
Identities = 40/155 (25%), Positives = 83/155 (53%), Gaps = 6/155 (3%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLA 390
+++ F Q+ L Y+H + I+H D+K NVF+ ++++GD G+A L ++H +A
Sbjct: 108 VVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTN---IIKVGDLGIARVL-ENHCDMA 163
Query: 389 ---LGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL--VEPFVTDMERVKTITDLRKGQI 228
+GT Y +PE + N KSD+++LG + E+ ++ + + + +G++
Sbjct: 164 STLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKL 223
Query: 227 PAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
PA P++A +I ++ ++P +R +L +
Sbjct: 224 PAMPRDYSPELAELIRTMLSKRPEERPSVRSILRQ 258
>EF560744-1|ABQ59054.1| 841|Homo sapiens NEK4 protein protein.
Length = 841
Score = 68.1 bits (159), Expect = 3e-11
Identities = 40/155 (25%), Positives = 83/155 (53%), Gaps = 6/155 (3%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLA 390
+++ F Q+ L Y+H + I+H D+K NVF+ ++++GD G+A L ++H +A
Sbjct: 108 VVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTN---IIKVGDLGIARVL-ENHCDMA 163
Query: 389 ---LGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL--VEPFVTDMERVKTITDLRKGQI 228
+GT Y +PE + N KSD+++LG + E+ ++ + + + +G++
Sbjct: 164 STLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKL 223
Query: 227 PAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
PA P++A +I ++ ++P +R +L +
Sbjct: 224 PAMPRDYSPELAELIRTMLSKRPEERPSVRSILRQ 258
>BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein.
Length = 781
Score = 68.1 bits (159), Expect = 3e-11
Identities = 40/155 (25%), Positives = 83/155 (53%), Gaps = 6/155 (3%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLA 390
+++ F Q+ L Y+H + I+H D+K NVF+ ++++GD G+A L ++H +A
Sbjct: 108 VVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTN---IIKVGDLGIARVL-ENHCDMA 163
Query: 389 ---LGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL--VEPFVTDMERVKTITDLRKGQI 228
+GT Y +PE + N KSD+++LG + E+ ++ + + + +G++
Sbjct: 164 STLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKL 223
Query: 227 PAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
PA P++A +I ++ ++P +R +L +
Sbjct: 224 PAMPRDYSPELAELIRTMLSKRPEERPSVRSILRQ 258
>BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 506
Score = 68.1 bits (159), Expect = 3e-11
Identities = 51/156 (32%), Positives = 86/156 (55%), Gaps = 7/156 (4%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ--QSH 402
D++++ FTQ+ G+++IH + ++H DIK N+F+ + G V+LGDFG A L +
Sbjct: 102 DMILNWFTQMCLGVNHIHKKRVLHRDIKSKNIFLT--QNG-KVKLGDFGSARLLSNPMAF 158
Query: 401 SGLALGTHMYAAPEQLDG-QCNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKG 234
+ +GT Y PE + N KSD++SLG IL EL PF + + I + +G
Sbjct: 159 ACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWK-NLILKVCQG 217
Query: 233 QIPAHLTANYP-KIAHIIGKLVQRKPSKRLDTAQLL 129
I + L ++Y ++ ++ ++ +R PS R LL
Sbjct: 218 CI-SPLPSHYSYELQFLVKQMFKRNPSHRPSATTLL 252
>AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 3 protein.
Length = 507
Score = 68.1 bits (159), Expect = 3e-11
Identities = 51/156 (32%), Positives = 86/156 (55%), Gaps = 7/156 (4%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ--QSH 402
D++++ FTQ+ G+++IH + ++H DIK N+F+ + G V+LGDFG A L +
Sbjct: 102 DMILNWFTQMCLGVNHIHKKRVLHRDIKSKNIFLT--QNG-KVKLGDFGSARLLSNPMAF 158
Query: 401 SGLALGTHMYAAPEQLDG-QCNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKG 234
+ +GT Y PE + N KSD++SLG IL EL PF + + I + +G
Sbjct: 159 ACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWK-NLILKVCQG 217
Query: 233 QIPAHLTANYP-KIAHIIGKLVQRKPSKRLDTAQLL 129
I + L ++Y ++ ++ ++ +R PS R LL
Sbjct: 218 CI-SPLPSHYSYELQFLVKQMFKRNPSHRPSATTLL 252
>AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens
cDNA FLJ16392 fis, clone TRACH2020048, moderately
similar to Mus musculus serine/threonine-protein kinase
NEK3 (Nek3) mRNA. ).
Length = 510
Score = 68.1 bits (159), Expect = 3e-11
Identities = 51/156 (32%), Positives = 86/156 (55%), Gaps = 7/156 (4%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ--QSH 402
D++++ FTQ+ G+++IH + ++H DIK N+F+ + G V+LGDFG A L +
Sbjct: 123 DMILNWFTQMCLGVNHIHKKRVLHRDIKSKNIFLT--QNG-KVKLGDFGSARLLSNPMAF 179
Query: 401 SGLALGTHMYAAPEQLDG-QCNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKG 234
+ +GT Y PE + N KSD++SLG IL EL PF + + I + +G
Sbjct: 180 ACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWK-NLILKVCQG 238
Query: 233 QIPAHLTANYP-KIAHIIGKLVQRKPSKRLDTAQLL 129
I + L ++Y ++ ++ ++ +R PS R LL
Sbjct: 239 CI-SPLPSHYSYELQFLVKQMFKRNPSHRPSATTLL 273
>AF069604-1|AAD15924.1| 560|Homo sapiens myosin light chain kinase
isoform 4 protein.
Length = 560
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/176 (27%), Positives = 84/176 (47%), Gaps = 6/176 (3%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHS-GLA 390
I Q+ G+ YIH +GI+H D+KP N+ + ++ G ++L DFGLA L+ + S +
Sbjct: 210 IKYMRQISEGVEYIHKQGIVHLDLKPENI-MCVNKTGTRIKLIDFGLARRLENAGSLKVL 268
Query: 389 LGTHMYAAPEQLDGQCNPKSDMYSLGIILLELV---EPFV--TDMERVKTITDLRKGQIP 225
GT + APE ++ + +DM+S+G+I LV PF+ D E + +T
Sbjct: 269 FGTPEFVAPEVINYEPIDATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDD 328
Query: 224 AHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAK 57
I L+++ RLD Q L+ + + K+ + L ++ K
Sbjct: 329 EAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKK 384
>AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein
kinase 3 protein.
Length = 489
Score = 68.1 bits (159), Expect = 3e-11
Identities = 51/156 (32%), Positives = 86/156 (55%), Gaps = 7/156 (4%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ--QSH 402
D++++ FTQ+ G+++IH + ++H DIK N+F+ + G V+LGDFG A L +
Sbjct: 102 DMILNWFTQMCLGVNHIHKKRVLHRDIKSKNIFLT--QNG-KVKLGDFGSARLLSNPMAF 158
Query: 401 SGLALGTHMYAAPEQLDG-QCNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKG 234
+ +GT Y PE + N KSD++SLG IL EL PF + + I + +G
Sbjct: 159 ACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWK-NLILKVCQG 217
Query: 233 QIPAHLTANYP-KIAHIIGKLVQRKPSKRLDTAQLL 129
I + L ++Y ++ ++ ++ +R PS R LL
Sbjct: 218 CI-SPLPSHYSYELQFLVKQMFKRNPSHRPSATTLL 252
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 67.7 bits (158), Expect = 4e-11
Identities = 57/199 (28%), Positives = 100/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K DM++ G+IL L+ P D ++ + ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ +I K++ P+KR+ ++ L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 298 RKLKGAILTTMLATRNFSA 316
>U56816-1|AAC50949.1| 499|Homo sapiens kinase Myt1 protein.
Length = 499
Score = 67.3 bits (157), Expect = 5e-11
Identities = 46/146 (31%), Positives = 77/146 (52%), Gaps = 2/146 (1%)
Frame = -1
Query: 536 LHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG-LALGTHMYAAPE 360
L ++HS+G++H D+KP+N+F+ P +LGDFGL L + +G + G Y APE
Sbjct: 221 LAHLHSQGLVHLDVKPANIFLGPRG---RCKLGDFGLLVELGTAGAGEVQEGDPRYMAPE 277
Query: 359 QLDGQCNPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLTANY-PKIAHII 183
L G +D++SLG+ +LE V + + LR+G +P TA ++ ++
Sbjct: 278 LLQGSYGTAADVFSLGLTILE-VACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVL 336
Query: 182 GKLVQRKPSKRLDTAQLLEELKTLAE 105
+++ P R TA+ L L L +
Sbjct: 337 VMMLEPDPKLRA-TAEALLALPVLRQ 361
>L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-dependent
protein kinase isoform A protein.
Length = 306
Score = 67.3 bits (157), Expect = 5e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 52 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 110
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 111 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGTYDFPSPE 170
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 171 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 230
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L ML + NF +
Sbjct: 231 RKLKGAILTTMLVSRNFSA 249
>BC130011-1|AAI30012.1| 485|Homo sapiens PKMYT1 protein protein.
Length = 485
Score = 67.3 bits (157), Expect = 5e-11
Identities = 46/146 (31%), Positives = 77/146 (52%), Gaps = 2/146 (1%)
Frame = -1
Query: 536 LHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG-LALGTHMYAAPE 360
L ++HS+G++H D+KP+N+F+ P +LGDFGL L + +G + G Y APE
Sbjct: 221 LAHLHSQGLVHLDVKPANIFLGPRG---RCKLGDFGLLVELGTAGAGEVQEGDPRYMAPE 277
Query: 359 QLDGQCNPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLTANY-PKIAHII 183
L G +D++SLG+ +LE V + + LR+G +P TA ++ ++
Sbjct: 278 LLQGSYGTAADVFSLGLTILE-VACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVL 336
Query: 182 GKLVQRKPSKRLDTAQLLEELKTLAE 105
+++ P R TA+ L L L +
Sbjct: 337 VMMLEPDPKLRA-TAEALLALPVLRQ 361
>BC121162-1|AAI21163.1| 485|Homo sapiens PKMYT1 protein protein.
Length = 485
Score = 67.3 bits (157), Expect = 5e-11
Identities = 46/146 (31%), Positives = 77/146 (52%), Gaps = 2/146 (1%)
Frame = -1
Query: 536 LHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG-LALGTHMYAAPE 360
L ++HS+G++H D+KP+N+F+ P +LGDFGL L + +G + G Y APE
Sbjct: 221 LAHLHSQGLVHLDVKPANIFLGPRG---RCKLGDFGLLVELGTAGAGEVQEGDPRYMAPE 277
Query: 359 QLDGQCNPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLTANY-PKIAHII 183
L G +D++SLG+ +LE V + + LR+G +P TA ++ ++
Sbjct: 278 LLQGSYGTAADVFSLGLTILE-VACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVL 336
Query: 182 GKLVQRKPSKRLDTAQLLEELKTLAE 105
+++ P R TA+ L L L +
Sbjct: 337 VMMLEPDPKLRA-TAEALLALPVLRQ 361
>BC121161-1|AAI21162.1| 485|Homo sapiens PKMYT1 protein protein.
Length = 485
Score = 67.3 bits (157), Expect = 5e-11
Identities = 46/146 (31%), Positives = 77/146 (52%), Gaps = 2/146 (1%)
Frame = -1
Query: 536 LHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG-LALGTHMYAAPE 360
L ++HS+G++H D+KP+N+F+ P +LGDFGL L + +G + G Y APE
Sbjct: 221 LAHLHSQGLVHLDVKPANIFLGPRG---RCKLGDFGLLVELGTAGAGEVQEGDPRYMAPE 277
Query: 359 QLDGQCNPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLTANY-PKIAHII 183
L G +D++SLG+ +LE V + + LR+G +P TA ++ ++
Sbjct: 278 LLQGSYGTAADVFSLGLTILE-VACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVL 336
Query: 182 GKLVQRKPSKRLDTAQLLEELKTLAE 105
+++ P R TA+ L L L +
Sbjct: 337 VMMLEPDPKLRA-TAEALLALPVLRQ 361
>BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein.
Length = 453
Score = 67.3 bits (157), Expect = 5e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 54 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 112
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 113 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 172
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 173 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 232
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L ML + NF +
Sbjct: 233 RKLKGAILTTMLVSRNFSA 251
>AL713896-5|CAI13790.1| 529|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 529
Score = 67.3 bits (157), Expect = 5e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L ML + NF +
Sbjct: 298 RKLKGAILTTMLVSRNFSA 316
>AL713896-4|CAI13789.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 67.3 bits (157), Expect = 5e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L ML + NF +
Sbjct: 298 RKLKGAILTTMLVSRNFSA 316
>AL713896-1|CAI13787.1| 453|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 453
Score = 67.3 bits (157), Expect = 5e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 54 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 112
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 113 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 172
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 173 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 232
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L ML + NF +
Sbjct: 233 RKLKGAILTTMLVSRNFSA 251
>AL596247-5|CAI13965.1| 529|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 529
Score = 67.3 bits (157), Expect = 5e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L ML + NF +
Sbjct: 298 RKLKGAILTTMLVSRNFSA 316
>AL596247-4|CAI13966.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 67.3 bits (157), Expect = 5e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L ML + NF +
Sbjct: 298 RKLKGAILTTMLVSRNFSA 316
>AL596247-1|CAI13964.1| 453|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 453
Score = 67.3 bits (157), Expect = 5e-11
Identities = 58/199 (29%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 54 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 112
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 113 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 172
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 173 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 232
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L ML + NF +
Sbjct: 233 RKLKGAILTTMLVSRNFSA 251
>AF549406-1|AAN40703.1| 499|Homo sapiens membrane-associated
tyrosine- and threonine-specific cdc2-inhibitory kinase
protein.
Length = 499
Score = 67.3 bits (157), Expect = 5e-11
Identities = 46/146 (31%), Positives = 77/146 (52%), Gaps = 2/146 (1%)
Frame = -1
Query: 536 LHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG-LALGTHMYAAPE 360
L ++HS+G++H D+KP+N+F+ P +LGDFGL L + +G + G Y APE
Sbjct: 221 LAHLHSQGLVHLDVKPANIFLGPRG---RCKLGDFGLLVELGTAGAGEVQEGDPRYMAPE 277
Query: 359 QLDGQCNPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLTANY-PKIAHII 183
L G +D++SLG+ +LE V + + LR+G +P TA ++ ++
Sbjct: 278 LLQGSYGTAADVFSLGLTILE-VACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVL 336
Query: 182 GKLVQRKPSKRLDTAQLLEELKTLAE 105
+++ P R TA+ L L L +
Sbjct: 337 VMMLEPDPKLRA-TAEALLALPVLRQ 361
>AF014118-1|AAB71843.1| 499|Homo sapiens membrane-associated kinase
protein.
Length = 499
Score = 67.3 bits (157), Expect = 5e-11
Identities = 46/146 (31%), Positives = 77/146 (52%), Gaps = 2/146 (1%)
Frame = -1
Query: 536 LHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG-LALGTHMYAAPE 360
L ++HS+G++H D+KP+N+F+ P +LGDFGL L + +G + G Y APE
Sbjct: 221 LAHLHSQGLVHLDVKPANIFLGPRG---RCKLGDFGLLVELGTAGAGEVQEGDPRYMAPE 277
Query: 359 QLDGQCNPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLTANY-PKIAHII 183
L G +D++SLG+ +LE V + + LR+G +P TA ++ ++
Sbjct: 278 LLQGSYGTAADVFSLGLTILE-VACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVL 336
Query: 182 GKLVQRKPSKRLDTAQLLEELKTLAE 105
+++ P R TA+ L L L +
Sbjct: 337 VMMLEPDPKLRA-TAEALLALPVLRQ 361
>AC004235-1|AAC04477.1| 495|Homo sapiens Myt1 protein.
Length = 495
Score = 67.3 bits (157), Expect = 5e-11
Identities = 46/146 (31%), Positives = 77/146 (52%), Gaps = 2/146 (1%)
Frame = -1
Query: 536 LHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG-LALGTHMYAAPE 360
L ++HS+G++H D+KP+N+F+ P +LGDFGL L + +G + G Y APE
Sbjct: 217 LAHLHSQGLVHLDVKPANIFLGPRG---RCKLGDFGLLVELGTAGAGEVQEGDPRYMAPE 273
Query: 359 QLDGQCNPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLTANY-PKIAHII 183
L G +D++SLG+ +LE V + + LR+G +P TA ++ ++
Sbjct: 274 LLQGSYGTAADVFSLGLTILE-VACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVL 332
Query: 182 GKLVQRKPSKRLDTAQLLEELKTLAE 105
+++ P R TA+ L L L +
Sbjct: 333 VMMLEPDPKLRA-TAEALLALPVLRQ 357
>AC004233-1|AAC04478.1| 499|Homo sapiens Myt1 protein.
Length = 499
Score = 67.3 bits (157), Expect = 5e-11
Identities = 46/146 (31%), Positives = 77/146 (52%), Gaps = 2/146 (1%)
Frame = -1
Query: 536 LHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG-LALGTHMYAAPE 360
L ++HS+G++H D+KP+N+F+ P +LGDFGL L + +G + G Y APE
Sbjct: 221 LAHLHSQGLVHLDVKPANIFLGPRG---RCKLGDFGLLVELGTAGAGEVQEGDPRYMAPE 277
Query: 359 QLDGQCNPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLTANY-PKIAHII 183
L G +D++SLG+ +LE V + + LR+G +P TA ++ ++
Sbjct: 278 LLQGSYGTAADVFSLGLTILE-VACNMELPHGGEGWQQLRQGYLPPEFTAGLSSELRSVL 336
Query: 182 GKLVQRKPSKRLDTAQLLEELKTLAE 105
+++ P R TA+ L L L +
Sbjct: 337 VMMLEPDPKLRA-TAEALLALPVLRQ 361
>U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-dependent
protein kinase II protein.
Length = 315
Score = 66.9 bits (156), Expect = 7e-11
Identities = 58/197 (29%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L ML + NF
Sbjct: 298 RKLKGAILTTMLVSRNF 314
>BC034044-1|AAH34044.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 66.9 bits (156), Expect = 7e-11
Identities = 58/197 (29%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L ML + NF
Sbjct: 298 RKLKGAILTTMLVSRNF 314
>BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein.
Length = 482
Score = 66.9 bits (156), Expect = 7e-11
Identities = 48/154 (31%), Positives = 82/154 (53%), Gaps = 6/154 (3%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS--HSG 396
+I+ F QL+ G+ Y+H R I+H D+K NVF+ + L+++GDFG++ L S +
Sbjct: 135 IIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNN----LLKIGDFGVSRLLMGSCDLAT 190
Query: 395 LALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL--VEPFVTDMERVKTITDLRKGQIP 225
GT Y +PE L Q + KSD++SL IL E+ + + + + +G P
Sbjct: 191 TLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTP 250
Query: 224 AHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLE 126
+ L YPK + I+ ++ + PS R ++L+
Sbjct: 251 S-LPERYPKELNAIMESMLNKNPSLRPSAIEILK 283
>AL713896-3|CAI13791.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 66.9 bits (156), Expect = 7e-11
Identities = 58/197 (29%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L ML + NF
Sbjct: 298 RKLKGAILTTMLVSRNF 314
>AL713896-2|CAI13788.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 66.9 bits (156), Expect = 7e-11
Identities = 58/197 (29%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L ML + NF
Sbjct: 298 RKLKGAILTTMLVSRNF 314
>AL596247-3|CAI13968.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 66.9 bits (156), Expect = 7e-11
Identities = 58/197 (29%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L ML + NF
Sbjct: 298 RKLKGAILTTMLVSRNF 314
>AL596247-2|CAI13967.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 66.9 bits (156), Expect = 7e-11
Identities = 58/197 (29%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L ML + NF
Sbjct: 298 RKLKGAILTTMLVSRNF 314
>AJ296290-1|CAC15059.1| 2382|Homo sapiens putative protein kinase
protein.
Length = 2382
Score = 66.9 bits (156), Expect = 7e-11
Identities = 53/192 (27%), Positives = 93/192 (48%), Gaps = 7/192 (3%)
Frame = -1
Query: 578 IDLLIDMFTQLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS 405
I +L Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S
Sbjct: 321 IKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRAS 378
Query: 404 HSGLALGTHMYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKG 234
+ +GT + APE + + + D+Y+ G+ +LE+ P+ + + G
Sbjct: 379 FAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSG 438
Query: 233 QIPAHL-TANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAK 57
PA P++ II +++ +R LL A +++T +R ELA +
Sbjct: 439 VKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNH----AFFQEET--GVRVELAEE 492
Query: 56 DD-EIAKLKMML 24
DD E +K+ L
Sbjct: 493 DDGEKIAIKLWL 504
>AF415197-1|AAM33514.1| 566|Homo sapiens
calcium/calmodulin-dependent protein kinase II gamma
protein.
Length = 566
Score = 66.9 bits (156), Expect = 7e-11
Identities = 58/197 (29%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ +++IH I+H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 97 QILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFA-GT 155
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 156 PGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 215
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ Q L+ + T+A ++ +T+ LR+ A
Sbjct: 216 WDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNAR 275
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L ML + NF
Sbjct: 276 RKLKGAILTTMLVSRNF 292
>AF061944-1|AAF31483.1| 670|Homo sapiens kinase deficient protein
KDP protein.
Length = 670
Score = 66.9 bits (156), Expect = 7e-11
Identities = 53/192 (27%), Positives = 93/192 (48%), Gaps = 7/192 (3%)
Frame = -1
Query: 578 IDLLIDMFTQLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS 405
I +L Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S
Sbjct: 321 IKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRAS 378
Query: 404 HSGLALGTHMYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKG 234
+ +GT + APE + + + D+Y+ G+ +LE+ P+ + + G
Sbjct: 379 FAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSG 438
Query: 233 QIPAHL-TANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAK 57
PA P++ II +++ +R LL A +++T +R ELA +
Sbjct: 439 VKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNH----AFFQEET--GVRVELAEE 492
Query: 56 DD-EIAKLKMML 24
DD E +K+ L
Sbjct: 493 DDGEKIAIKLWL 504
>AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S
protein.
Length = 470
Score = 66.9 bits (156), Expect = 7e-11
Identities = 48/154 (31%), Positives = 82/154 (53%), Gaps = 6/154 (3%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS--HSG 396
+I+ F QL+ G+ Y+H R I+H D+K NVF+ + L+++GDFG++ L S +
Sbjct: 135 IIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNN----LLKIGDFGVSRLLMGSCDLAT 190
Query: 395 LALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL--VEPFVTDMERVKTITDLRKGQIP 225
GT Y +PE L Q + KSD++SL IL E+ + + + + +G P
Sbjct: 191 TLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTP 250
Query: 224 AHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLE 126
+ L YPK + I+ ++ + PS R ++L+
Sbjct: 251 S-LPERYPKELNAIMESMLNKNPSLRPSAIEILK 283
>AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L
protein.
Length = 645
Score = 66.9 bits (156), Expect = 7e-11
Identities = 48/154 (31%), Positives = 82/154 (53%), Gaps = 6/154 (3%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS--HSG 396
+I+ F QL+ G+ Y+H R I+H D+K NVF+ + L+++GDFG++ L S +
Sbjct: 135 IIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNN----LLKIGDFGVSRLLMGSCDLAT 190
Query: 395 LALGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL--VEPFVTDMERVKTITDLRKGQIP 225
GT Y +PE L Q + KSD++SL IL E+ + + + + +G P
Sbjct: 191 TLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTP 250
Query: 224 AHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLE 126
+ L YPK + I+ ++ + PS R ++L+
Sbjct: 251 S-LPERYPKELNAIMESMLNKNPSLRPSAIEILK 283
>AB002342-1|BAA20802.2| 2066|Homo sapiens KIAA0344 protein.
Length = 2066
Score = 66.9 bits (156), Expect = 7e-11
Identities = 53/192 (27%), Positives = 93/192 (48%), Gaps = 7/192 (3%)
Frame = -1
Query: 578 IDLLIDMFTQLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQS 405
I +L Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S
Sbjct: 253 IKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRAS 310
Query: 404 HSGLALGTHMYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKG 234
+ +GT + APE + + + D+Y+ G+ +LE+ P+ + + G
Sbjct: 311 FAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSG 370
Query: 233 QIPAHL-TANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAK 57
PA P++ II +++ +R LL A +++T +R ELA +
Sbjct: 371 VKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNH----AFFQEET--GVRVELAEE 424
Query: 56 DD-EIAKLKMML 24
DD E +K+ L
Sbjct: 425 DDGEKIAIKLWL 436
>CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein.
Length = 431
Score = 66.5 bits (155), Expect = 9e-11
Identities = 53/181 (29%), Positives = 90/181 (49%), Gaps = 6/181 (3%)
Frame = -1
Query: 614 AKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGD 435
A D+ P ++ + + ++++GL Y+HS IH DIK +NV ++ H V+L D
Sbjct: 107 ALDLLEPGPLDETQIAT-ILREILKGLDYLHSEKKIHRDIKAANVLLSEHGE---VKLAD 162
Query: 434 FGLACPL--QQSHSGLALGTHMYAAPEQL-DGQCNPKSDMYSLGIILLELV--EPFVTDM 270
G+A L Q +GT + APE + + K+D++SLGI +EL EP +++
Sbjct: 163 IGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELARGEPPHSEL 222
Query: 269 ERVKTITDLRKGQIPAHLTANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDD 93
+K + + K P L NY K + + + ++PS R +LL+ K + N
Sbjct: 223 HPMKVLFLIPKNN-PPTLEGNYSKPLKEFVEACLNKEPSFRPTAKELLKH-KFILRNAKK 280
Query: 92 T 90
T
Sbjct: 281 T 281
>BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related
kinase protein.
Length = 416
Score = 66.5 bits (155), Expect = 9e-11
Identities = 52/163 (31%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL--QQSHSGLAL 387
M ++++GL Y+HS IH DIK +NV ++ +G V+L DFG+A L Q +
Sbjct: 124 MLKEILKGLDYLHSEKKIHRDIKAANVLLS-EQGD--VKLADFGVAGQLTDTQIKRNTFV 180
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHL 216
GT + APE + + K+D++SLGI +EL EP +DM ++ + + K P L
Sbjct: 181 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNN-PPTL 239
Query: 215 TANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDT 90
++ K I + + PS R +LL+ K + +N T
Sbjct: 240 VGDFTKSFKEFIDACLNKDPSFRPTAKELLKH-KFIVKNSKKT 281
>BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 66.5 bits (155), Expect = 9e-11
Identities = 52/163 (31%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL--QQSHSGLAL 387
M ++++GL Y+HS IH DIK +NV ++ +G V+L DFG+A L Q +
Sbjct: 124 MLKEILKGLDYLHSEKKIHRDIKAANVLLS-EQGD--VKLADFGVAGQLTDTQIKRNTFV 180
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHL 216
GT + APE + + K+D++SLGI +EL EP +DM ++ + + K P L
Sbjct: 181 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNN-PPTL 239
Query: 215 TANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDT 90
++ K I + + PS R +LL+ K + +N T
Sbjct: 240 VGDFTKSFKEFIDACLNKDPSFRPTAKELLKH-KFIVKNSKKT 281
>BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 66.5 bits (155), Expect = 9e-11
Identities = 52/163 (31%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL--QQSHSGLAL 387
M ++++GL Y+HS IH DIK +NV ++ +G V+L DFG+A L Q +
Sbjct: 124 MLKEILKGLDYLHSEKKIHRDIKAANVLLS-EQGD--VKLADFGVAGQLTDTQIKRNTFV 180
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHL 216
GT + APE + + K+D++SLGI +EL EP +DM ++ + + K P L
Sbjct: 181 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNN-PPTL 239
Query: 215 TANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDT 90
++ K I + + PS R +LL+ K + +N T
Sbjct: 240 VGDFTKSFKEFIDACLNKDPSFRPTAKELLKH-KFIVKNSKKT 281
>BC040457-1|AAH40457.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II alpha protein.
Length = 478
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/197 (29%), Positives = 98/197 (49%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFA-GT 176
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ + ++ G P+
Sbjct: 177 PGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYKQIKAGAYDFPSPE 236
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ +I K++ PSKR+ A+ L+ T+A ++ +T+ L++ A
Sbjct: 237 WDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNAR 296
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L MLA NF
Sbjct: 297 RKLKGAILTTMLATRNF 313
>BC019070-1|AAH19070.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II beta protein.
Length = 503
Score = 66.5 bits (155), Expect = 9e-11
Identities = 56/199 (28%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 298 RKLKGAILTTMLATRNFSA 316
>AL583839-7|CAO03350.1| 2219|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2219
Score = 66.5 bits (155), Expect = 9e-11
Identities = 50/172 (29%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S + +GT
Sbjct: 299 QILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 356
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHL-TA 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 357 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKV 416
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKD 54
+ P+I IIG+ + + +R + LL A +DT +R ELA +D
Sbjct: 417 HDPEIKEIIGECICKNKEERYEIKDLLSH----AFFAEDT--GVRVELAEED 462
>AL583839-6|CAI12344.3| 2297|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2297
Score = 66.5 bits (155), Expect = 9e-11
Identities = 50/172 (29%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S + +GT
Sbjct: 304 QILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 361
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHL-TA 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 362 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKV 421
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKD 54
+ P+I IIG+ + + +R + LL A +DT +R ELA +D
Sbjct: 422 HDPEIKEIIGECICKNKEERYEIKDLLSH----AFFAEDT--GVRVELAEED 467
>AL390760-3|CAO03647.1| 2219|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2219
Score = 66.5 bits (155), Expect = 9e-11
Identities = 50/172 (29%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S + +GT
Sbjct: 299 QILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 356
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHL-TA 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 357 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKV 416
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKD 54
+ P+I IIG+ + + +R + LL A +DT +R ELA +D
Sbjct: 417 HDPEIKEIIGECICKNKEERYEIKDLLSH----AFFAEDT--GVRVELAEED 462
>AL390760-2|CAO03646.1| 790|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 790
Score = 66.5 bits (155), Expect = 9e-11
Identities = 50/172 (29%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S + +GT
Sbjct: 304 QILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 361
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHL-TA 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 362 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKV 421
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKD 54
+ P+I IIG+ + + +R + LL A +DT +R ELA +D
Sbjct: 422 HDPEIKEIIGECICKNKEERYEIKDLLSH----AFFAEDT--GVRVELAEED 467
>AL390760-1|CAH73069.3| 2297|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2297
Score = 66.5 bits (155), Expect = 9e-11
Identities = 50/172 (29%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S + +GT
Sbjct: 304 QILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 361
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHL-TA 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 362 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKV 421
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKD 54
+ P+I IIG+ + + +R + LL A +DT +R ELA +D
Sbjct: 422 HDPEIKEIIGECICKNKEERYEIKDLLSH----AFFAEDT--GVRVELAEED 467
>AL354991-3|CAO03639.1| 2219|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2219
Score = 66.5 bits (155), Expect = 9e-11
Identities = 50/172 (29%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S + +GT
Sbjct: 299 QILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 356
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHL-TA 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 357 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKV 416
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKD 54
+ P+I IIG+ + + +R + LL A +DT +R ELA +D
Sbjct: 417 HDPEIKEIIGECICKNKEERYEIKDLLSH----AFFAEDT--GVRVELAEED 462
>AL354991-2|CAI14449.3| 2297|Homo sapiens WNK lysine deficient
protein kinase 2 protein.
Length = 2297
Score = 66.5 bits (155), Expect = 9e-11
Identities = 50/172 (29%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S + +GT
Sbjct: 304 QILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 361
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHL-TA 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 362 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKV 421
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKD 54
+ P+I IIG+ + + +R + LL A +DT +R ELA +D
Sbjct: 422 HDPEIKEIIGECICKNKEERYEIKDLLSH----AFFAEDT--GVRVELAEED 467
>AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related
kinase (MST4) protein.
Length = 416
Score = 66.5 bits (155), Expect = 9e-11
Identities = 52/163 (31%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL--QQSHSGLAL 387
M ++++GL Y+HS IH DIK +NV ++ +G V+L DFG+A L Q +
Sbjct: 124 MLKEILKGLDYLHSEKKIHRDIKAANVLLS-EQGD--VKLADFGVAGQLTDTQIKRNTFV 180
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHL 216
GT + APE + + K+D++SLGI +EL EP +DM ++ + + K P L
Sbjct: 181 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNN-PPTL 239
Query: 215 TANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDT 90
++ K I + + PS R +LL+ K + +N T
Sbjct: 240 VGDFTKSFKEFIDACLNKDPSFRPTAKELLKH-KFIVKNSKKT 281
>AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens
cDNA FLJ90669 fis, clone PLACE1005519, moderately
similar to Homo sapiens STE20-like kinase 3 (mst-3)
mRNA. ).
Length = 392
Score = 66.5 bits (155), Expect = 9e-11
Identities = 52/163 (31%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL--QQSHSGLAL 387
M ++++GL Y+HS IH DIK +NV ++ +G V+L DFG+A L Q +
Sbjct: 124 MLKEILKGLDYLHSEKKIHRDIKAANVLLS-EQGD--VKLADFGVAGQLTDTQIKRNTFV 180
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHL 216
GT + APE + + K+D++SLGI +EL EP +DM ++ + + K P L
Sbjct: 181 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNN-PPTL 239
Query: 215 TANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDT 90
++ K I + + PS R +LL+ K + +N T
Sbjct: 240 VGDFTKSFKEFIDACLNKDPSFRPTAKELLKH-KFIVKNSKKT 281
>AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens
cDNA FLJ90626 fis, clone PLACE1003135, weakly similar to
SPORULATION-SPECIFIC PROTEIN 1 (EC 2.7.1.-). ).
Length = 339
Score = 66.5 bits (155), Expect = 9e-11
Identities = 52/163 (31%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL--QQSHSGLAL 387
M ++++GL Y+HS IH DIK +NV ++ +G V+L DFG+A L Q +
Sbjct: 47 MLKEILKGLDYLHSEKKIHRDIKAANVLLS-EQGD--VKLADFGVAGQLTDTQIKRNTFV 103
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHL 216
GT + APE + + K+D++SLGI +EL EP +DM ++ + + K P L
Sbjct: 104 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNN-PPTL 162
Query: 215 TANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDT 90
++ K I + + PS R +LL+ K + +N T
Sbjct: 163 VGDFTKSFKEFIDACLNKDPSFRPTAKELLKH-KFIVKNSKKT 204
>AK000556-1|BAA91251.1| 293|Homo sapiens protein ( Homo sapiens
cDNA FLJ20549 fis, clone KAT11561. ).
Length = 293
Score = 66.5 bits (155), Expect = 9e-11
Identities = 52/163 (31%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL--QQSHSGLAL 387
M ++++GL Y+HS IH DIK +NV ++ +G V+L DFG+A L Q +
Sbjct: 1 MLKEILKGLDYLHSEKKIHRDIKAANVLLS-EQGD--VKLADFGVAGQLTDTQIKRNTFV 57
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHL 216
GT + APE + + K+D++SLGI +EL EP +DM ++ + + K P L
Sbjct: 58 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNN-PPTL 116
Query: 215 TANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDT 90
++ K I + + PS R +LL+ K + +N T
Sbjct: 117 VGDFTKSFKEFIDACLNKDPSFRPTAKELLKH-KFIVKNSKKT 158
>AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 4 protein.
Length = 518
Score = 66.5 bits (155), Expect = 9e-11
Identities = 56/199 (28%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 298 RKLKGAILTTMLATRNFSA 316
>AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 2 protein.
Length = 479
Score = 66.5 bits (155), Expect = 9e-11
Identities = 56/199 (28%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 298 RKLKGAILTTMLATRNFSA 316
>AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 1 protein.
Length = 503
Score = 66.5 bits (155), Expect = 9e-11
Identities = 56/199 (28%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 298 RKLKGAILTTMLATRNFSA 316
>AJ242724-1|CAB44308.5| 2297|Homo sapiens putative mitogen-activated
protein kinase kinase kinase protein.
Length = 2297
Score = 66.5 bits (155), Expect = 9e-11
Identities = 50/172 (29%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S + +GT
Sbjct: 304 QILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 361
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHL-TA 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 362 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKV 421
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKD 54
+ P+I IIG+ + + +R + LL A +DT +R ELA +D
Sbjct: 422 HDPEIKEIIGECICKNKEERYEIKDLLSH----AFFAEDT--GVRVELAEED 467
>AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 66.5 bits (155), Expect = 9e-11
Identities = 52/163 (31%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL--QQSHSGLAL 387
M ++++GL Y+HS IH DIK +NV ++ +G V+L DFG+A L Q +
Sbjct: 124 MLKEILKGLDYLHSEKKIHRDIKAANVLLS-EQGD--VKLADFGVAGQLTDTQIKRNTFV 180
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHL 216
GT + APE + + K+D++SLGI +EL EP +DM ++ + + K P L
Sbjct: 181 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNN-PPTL 239
Query: 215 TANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDT 90
++ K I + + PS R +LL+ K + +N T
Sbjct: 240 VGDFTKSFKEFIDACLNKDPSFRPTAKELLKH-KFIVKNSKKT 281
>AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4
protein.
Length = 416
Score = 66.5 bits (155), Expect = 9e-11
Identities = 52/163 (31%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL--QQSHSGLAL 387
M ++++GL Y+HS IH DIK +NV ++ +G V+L DFG+A L Q +
Sbjct: 124 MLKEILKGLDYLHSEKKIHRDIKAANVLLS-EQGD--VKLADFGVAGQLTDTQIKRNTFV 180
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHL 216
GT + APE + + K+D++SLGI +EL EP +DM ++ + + K P L
Sbjct: 181 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNN-PPTL 239
Query: 215 TANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDT 90
++ K I + + PS R +LL+ K + +N T
Sbjct: 240 VGDFTKSFKEFIDACLNKDPSFRPTAKELLKH-KFIVKNSKKT 281
>AF145711-1|AAD30559.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha-B
subunit protein.
Length = 489
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/197 (29%), Positives = 98/197 (49%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFA-GT 176
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ + ++ G P+
Sbjct: 177 PGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 236
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ +I K++ PSKR+ A+ L+ T+A ++ +T+ L++ A
Sbjct: 237 WDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNAR 296
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L MLA NF
Sbjct: 297 RKLKGAILTTMLATRNF 313
>AF145710-1|AAD30558.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha
subunit protein.
Length = 478
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/197 (29%), Positives = 98/197 (49%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFA-GT 176
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ + ++ G P+
Sbjct: 177 PGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 236
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ +I K++ PSKR+ A+ L+ T+A ++ +T+ L++ A
Sbjct: 237 WDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNAR 296
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L MLA NF
Sbjct: 297 RKLKGAILTTMLATRNF 313
>AF140350-1|AAD42070.1| 449|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 7
subunit protein.
Length = 449
Score = 66.5 bits (155), Expect = 9e-11
Identities = 56/199 (28%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 298 RKLKGAILTTMLATRNFSA 316
>AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent
protein kinase II alpha protein.
Length = 478
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/197 (29%), Positives = 98/197 (49%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 118 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFA-GT 176
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ + ++ G P+
Sbjct: 177 PGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 236
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ +I K++ PSKR+ A+ L+ T+A ++ +T+ L++ A
Sbjct: 237 WDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNAR 296
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L MLA NF
Sbjct: 297 RKLKGAILTTMLATRNF 313
>AF083419-1|AAD42038.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e
subunit protein.
Length = 517
Score = 66.5 bits (155), Expect = 9e-11
Identities = 56/199 (28%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 298 RKLKGAILTTMLATRNFSA 316
>AB051547-1|BAB21851.2| 2219|Homo sapiens KIAA1760 protein protein.
Length = 2219
Score = 66.5 bits (155), Expect = 9e-11
Identities = 50/172 (29%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S + +GT
Sbjct: 299 QILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 356
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHL-TA 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 357 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKV 416
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKD 54
+ P+I IIG+ + + +R + LL A +DT +R ELA +D
Sbjct: 417 HDPEIKEIIGECICKNKEERYEIKDLLSH----AFFAEDT--GVRVELAEED 462
>AB044546-1|BAB18648.1| 779|Homo sapiens mitogen-activated protein
kinase kinase kinase protein.
Length = 779
Score = 66.5 bits (155), Expect = 9e-11
Identities = 50/172 (29%), Positives = 85/172 (49%), Gaps = 6/172 (3%)
Frame = -1
Query: 551 QLVRGLHYIHSRG--IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q+++GL ++H+R IIH D+K N+F+ G V++GD GLA + S + +GT
Sbjct: 290 QILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 347
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLELVE---PFVTDMERVKTITDLRKGQIPAHL-TA 210
+ APE + + D+Y+ G+ +LE+ P+ + + G PA
Sbjct: 348 EFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPASFEKV 407
Query: 209 NYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKD 54
+ P+I IIG+ + + +R + LL A +DT +R ELA +D
Sbjct: 408 HDPEIKEIIGECICKNKEERYEIKDLLSH----AFFAEDT--GVRVELAEED 453
>AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protein
kinase MASK protein.
Length = 416
Score = 66.5 bits (155), Expect = 9e-11
Identities = 52/163 (31%), Positives = 84/163 (51%), Gaps = 6/163 (3%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL--QQSHSGLAL 387
M ++++GL Y+HS IH DIK +NV ++ +G V+L DFG+A L Q +
Sbjct: 124 MLKEILKGLDYLHSEKKIHRDIKAANVLLS-EQGD--VKLADFGVAGQLTDTQIKRNTFV 180
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHL 216
GT + APE + + K+D++SLGI +EL EP +DM ++ + + K P L
Sbjct: 181 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNN-PPTL 239
Query: 215 TANYPK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDT 90
++ K I + + PS R +LL+ K + +N T
Sbjct: 240 VGDFTKSFKEFIDACLNKDPSFRPTAKELLKH-KFIVKNSKKT 281
>AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein.
Length = 527
Score = 66.5 bits (155), Expect = 9e-11
Identities = 58/197 (29%), Positives = 98/197 (49%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 167 QILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFA-GT 225
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L K D+++ G+IL L+ P D ++ + ++ G P+
Sbjct: 226 PGYLSPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPE 285
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ +I K++ PSKR+ A+ L+ T+A ++ +T+ L++ A
Sbjct: 286 WDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNAR 345
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L MLA NF
Sbjct: 346 RKLKGAILTTMLATRNF 362
>U23460-1|AAC99802.1| 664|Homo sapiens proline rich
calmodulin-dependent protein kinase protein.
Length = 664
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L MLA NF
Sbjct: 298 RKLKGAILTTMLATRNF 314
>M80776-1|AAA58391.1| 689|Homo sapiens receptor kinase protein.
Length = 689
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/141 (28%), Positives = 75/141 (53%), Gaps = 6/141 (4%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMY 372
+++ GL ++H+R +++ D+KP+N+ + H V++ D GLAC + ++GTH Y
Sbjct: 300 EIILGLEHMHNRFVVYRDLKPANILLDEHGH---VRISDLGLACDFSKKKPHASVGTHGY 356
Query: 371 AAPEQLDG--QCNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQIPAHLTAN 207
APE L + +D +SLG +L +L+ PF + K D + L +
Sbjct: 357 MAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDS 416
Query: 206 Y-PKIAHIIGKLVQRKPSKRL 147
+ P++ ++ L+QR ++RL
Sbjct: 417 FSPELRSLLEGLLQRDVNRRL 437
>BC090863-1|AAH90863.1| 689|Homo sapiens ADRBK1 protein protein.
Length = 689
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/141 (28%), Positives = 75/141 (53%), Gaps = 6/141 (4%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMY 372
+++ GL ++H+R +++ D+KP+N+ + H V++ D GLAC + ++GTH Y
Sbjct: 300 EIILGLEHMHNRFVVYRDLKPANILLDEHGH---VRISDLGLACDFSKKKPHASVGTHGY 356
Query: 371 AAPEQLDG--QCNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQIPAHLTAN 207
APE L + +D +SLG +L +L+ PF + K D + L +
Sbjct: 357 MAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDS 416
Query: 206 Y-PKIAHIIGKLVQRKPSKRL 147
+ P++ ++ L+QR ++RL
Sbjct: 417 FSPELRSLLEGLLQRDVNRRL 437
>BC037963-1|AAH37963.1| 689|Homo sapiens adrenergic, beta, receptor
kinase 1 protein.
Length = 689
Score = 66.1 bits (154), Expect = 1e-10
Identities = 40/141 (28%), Positives = 75/141 (53%), Gaps = 6/141 (4%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMY 372
+++ GL ++H+R +++ D+KP+N+ + H V++ D GLAC + ++GTH Y
Sbjct: 300 EIILGLEHMHNRFVVYRDLKPANILLDEHGH---VRISDLGLACDFSKKKPHASVGTHGY 356
Query: 371 AAPEQLDG--QCNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQIPAHLTAN 207
APE L + +D +SLG +L +L+ PF + K D + L +
Sbjct: 357 MAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDS 416
Query: 206 Y-PKIAHIIGKLVQRKPSKRL 147
+ P++ ++ L+QR ++RL
Sbjct: 417 FSPELRSLLEGLLQRDVNRRL 437
>BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for
IMAGE:3913546) protein.
Length = 451
Score = 66.1 bits (154), Expect = 1e-10
Identities = 39/155 (25%), Positives = 82/155 (52%), Gaps = 6/155 (3%)
Frame = -1
Query: 569 LIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLA 390
+++ F Q+ L Y+H + I+H D+K NVF+ ++++GD G+A L ++H +A
Sbjct: 108 VVEWFVQIAMALQYLHEKHILHRDLKTQNVFLTRTN---IIKVGDLGIARVL-ENHCDMA 163
Query: 389 ---LGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLEL--VEPFVTDMERVKTITDLRKGQI 228
+GT Y +PE + N KSD+++LG + E+ ++ + + + +G++
Sbjct: 164 STLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKL 223
Query: 227 PAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
P P++A +I ++ ++P +R +L +
Sbjct: 224 PPMPRDYSPELAELIRTMLSKRPEERPSVRSILRQ 258
>AF112471-1|AAD03743.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 517
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/199 (28%), Positives = 101/199 (50%), Gaps = 16/199 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILXAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNFKS 3
+ + A L MLA NF +
Sbjct: 298 RKLKGAILTTMLATRNFSA 316
>AF081924-1|AAD42037.1| 492|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 6
subunit protein.
Length = 492
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L MLA NF
Sbjct: 298 RKLKGAILTTMLATRNF 314
>AF081572-1|AAD42036.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e'
subunit protein.
Length = 503
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L MLA NF
Sbjct: 298 RKLKGAILTTMLATRNF 314
>AF078803-1|AAD42035.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L MLA NF
Sbjct: 298 RKLKGAILTTMLATRNF 314
>X61157-1|CAA43470.1| 689|Homo sapiens beta-adrenergic receptor
kinase protein.
Length = 689
Score = 65.7 bits (153), Expect = 2e-10
Identities = 40/141 (28%), Positives = 75/141 (53%), Gaps = 6/141 (4%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMY 372
+++ GL ++H+R +++ D+KP+N+ + H V++ D GLAC + ++GTH Y
Sbjct: 300 EIILGLEHMHNRFVVYRDLKPANILLDEHGH---VRISDLGLACDFSKKKPHASVGTHGY 356
Query: 371 AAPEQLDG--QCNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQIPAHLTAN 207
APE L + +D +SLG +L +L+ PF + K D + L +
Sbjct: 357 MAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDS 416
Query: 206 Y-PKIAHIIGKLVQRKPSKRL 147
+ P++ ++ L+QR ++RL
Sbjct: 417 FSPELHSLLEGLLQRDVNRRL 437
>U08438-1|AAB60689.1| 689|Homo sapiens beta-adrenergic receptor
kinase protein.
Length = 689
Score = 65.7 bits (153), Expect = 2e-10
Identities = 40/141 (28%), Positives = 75/141 (53%), Gaps = 6/141 (4%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMY 372
+++ GL ++H+R +++ D+KP+N+ + H V++ D GLAC + ++GTH Y
Sbjct: 300 EIILGLEHMHNRFVVYRDLKPANILLDEHGH---VRISDLGLACDFSKKKPHASVGTHGY 356
Query: 371 AAPEQLDG--QCNPKSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQIPAHLTAN 207
APE L + +D +SLG +L +L+ PF + K D + L +
Sbjct: 357 MAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDS 416
Query: 206 Y-PKIAHIIGKLVQRKPSKRL 147
+ P++ ++ L+QR ++RL
Sbjct: 417 FSPELHSLLEGLLQRDVNRRL 437
>BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protein
kinase MST4 protein.
Length = 416
Score = 65.7 bits (153), Expect = 2e-10
Identities = 50/162 (30%), Positives = 81/162 (50%), Gaps = 5/162 (3%)
Frame = -1
Query: 560 MFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL--QQSHSGLAL 387
M ++++GL Y+HS IH DIK +NV ++ +G V+L DFG+A L Q +
Sbjct: 124 MLKEILKGLDYLHSEKKIHRDIKAANVLLS-EQGD--VKLADFGVAGQLTDTQIKRNTFV 180
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHL 216
GT + APE + + K+D++SLGI +EL EP +DM ++ + + K P +
Sbjct: 181 GTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLV 240
Query: 215 TANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDT 90
I + + PS R +LL+ K + +N T
Sbjct: 241 GDFTESFKEFIDACLNKDPSFRPTAKELLKH-KFIVKNSKKT 281
>AF112472-1|AAD03744.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 65.7 bits (153), Expect = 2e-10
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILXAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A ++ +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L MLA NF
Sbjct: 298 RKLKGAILTTMLATRNF 314
>AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein.
Length = 302
Score = 65.7 bits (153), Expect = 2e-10
Identities = 49/159 (30%), Positives = 79/159 (49%), Gaps = 10/159 (6%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGL----ACPLQQSHSGLA 390
F QL L ++HSR ++H DIKP+NVF+ +V+LGD GL + +HS
Sbjct: 142 FVQLCSALEHMHSRRVMHRDIKPANVFITATG---VVKLGDLGLGRFFSSKTTAAHS--L 196
Query: 389 LGTHMYAAPEQL-DGQCNPKSDMYSLGIILLE---LVEPFVTD-MERVKTITDLRKGQIP 225
+GT Y +PE++ + N KSD++SLG +L E L PF D M + + P
Sbjct: 197 VGTPYYMSPERIHENGYNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYP 256
Query: 224 AHLTANY-PKIAHIIGKLVQRKPSKRLDTAQLLEELKTL 111
+ +Y ++ ++ + P KR D + + K +
Sbjct: 257 PLPSDHYSEELRQLVNMCINPDPEKRPDVTYVYDVAKRM 295
>Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein.
Length = 445
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRG-----IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ 411
+ ++ + TQL L H R ++H D+KP+NVF+ +G V+LGDFGLA L
Sbjct: 111 EFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFL---DGKQNVKLGDFGLARILN 167
Query: 410 Q--SHSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLEL--VEPFVTDMERVKTITD 246
S + +GT Y +PEQ++ N KSD++SLG +L EL + P T + +
Sbjct: 168 HDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGK 227
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+R+G+ ++ II +++ K R ++LE
Sbjct: 228 IREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILE 267
>U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase 1
protein.
Length = 445
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRG-----IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ 411
+ ++ + TQL L H R ++H D+KP+NVF+ +G V+LGDFGLA L
Sbjct: 111 EFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFL---DGKQNVKLGDFGLARILN 167
Query: 410 Q--SHSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLEL--VEPFVTDMERVKTITD 246
S + +GT Y +PEQ++ N KSD++SLG +L EL + P T + +
Sbjct: 168 HDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGK 227
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+R+G+ ++ II +++ K R ++LE
Sbjct: 228 IREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILE 267
>BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRG-----IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ 411
+ ++ + TQL L H R ++H D+KP+NVF+ +G V+LGDFGLA L
Sbjct: 111 EFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFL---DGKQNVKLGDFGLARILN 167
Query: 410 Q--SHSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLEL--VEPFVTDMERVKTITD 246
S + +GT Y +PEQ++ N KSD++SLG +L EL + P T + +
Sbjct: 168 HDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGK 227
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+R+G+ ++ II +++ K R ++LE
Sbjct: 228 IREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILE 267
>BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein.
Length = 326
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRG-----IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ 411
+ ++ + TQL L H R ++H D+KP+NVF+ +G V+LGDFGLA L
Sbjct: 111 EFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFL---DGKQNVKLGDFGLARILN 167
Query: 410 Q--SHSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLEL--VEPFVTDMERVKTITD 246
S + +GT Y +PEQ++ N KSD++SLG +L EL + P T + +
Sbjct: 168 HDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGK 227
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+R+G+ ++ II +++ K R ++LE
Sbjct: 228 IREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILE 267
>BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRG-----IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ 411
+ ++ + TQL L H R ++H D+KP+NVF+ +G V+LGDFGLA L
Sbjct: 111 EFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFL---DGKQNVKLGDFGLARILN 167
Query: 410 Q--SHSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLEL--VEPFVTDMERVKTITD 246
S + +GT Y +PEQ++ N KSD++SLG +L EL + P T + +
Sbjct: 168 HDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGK 227
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+R+G+ ++ II +++ K R ++LE
Sbjct: 228 IREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILE 267
>AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase
protein.
Length = 384
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRG-----IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ 411
+ ++ + TQL L H R ++H D+KP+NVF+ +G V+LGDFGLA L
Sbjct: 111 EFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFL---DGKQNVKLGDFGLARILN 167
Query: 410 Q--SHSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLEL--VEPFVTDMERVKTITD 246
S + +GT Y +PEQ++ N KSD++SLG +L EL + P T + +
Sbjct: 168 HDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGK 227
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+R+G+ ++ II +++ K R ++LE
Sbjct: 228 IREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILE 267
>AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRG-----IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ 411
+ ++ + TQL L H R ++H D+KP+NVF+ +G V+LGDFGLA L
Sbjct: 111 EFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFL---DGKQNVKLGDFGLARILN 167
Query: 410 Q--SHSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLEL--VEPFVTDMERVKTITD 246
S + +GT Y +PEQ++ N KSD++SLG +L EL + P T + +
Sbjct: 168 HDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGK 227
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+R+G+ ++ II +++ K R ++LE
Sbjct: 228 IREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILE 267
>AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 variant protein.
Length = 445
Score = 65.3 bits (152), Expect = 2e-10
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRG-----IIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ 411
+ ++ + TQL L H R ++H D+KP+NVF+ +G V+LGDFGLA L
Sbjct: 111 EFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFL---DGKQNVKLGDFGLARILN 167
Query: 410 Q--SHSGLALGTHMYAAPEQLDGQC-NPKSDMYSLGIILLEL--VEPFVTDMERVKTITD 246
S + +GT Y +PEQ++ N KSD++SLG +L EL + P T + +
Sbjct: 168 HDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGK 227
Query: 245 LRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLE 126
+R+G+ ++ II +++ K R ++LE
Sbjct: 228 IREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILE 267
>AJ309861-1|CAC32991.1| 212|Homo sapiens putative protein kinase
WNK4 protein.
Length = 212
Score = 65.3 bits (152), Expect = 2e-10
Identities = 33/88 (37%), Positives = 54/88 (61%), Gaps = 2/88 (2%)
Frame = -1
Query: 551 QLVRGLHYIHSR--GIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTH 378
Q++RGLH++HSR I+H D+K NVF+ G V++GD GLA + S + +GT
Sbjct: 77 QILRGLHFLHSRVPPILHRDLKCDNVFITGPTGS--VKIGDLGLATLKRASFAKSVIGTP 134
Query: 377 MYAAPEQLDGQCNPKSDMYSLGIILLEL 294
+ APE + + + D+Y+ G+ +LE+
Sbjct: 135 EFMAPEMYEEKYDEAVDVYAFGMCMLEM 162
>X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase
protein.
Length = 458
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 7/177 (3%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHS-GLA 390
I Q+ G+ YIH +GI+H D+KP N+ + ++ G ++L DFGLA L+ + S +
Sbjct: 108 IKYMRQISEGVEYIHKQGIVHLDLKPENI-MCVNKTGTRIKLIDFGLARRLENAGSLKVL 166
Query: 389 LGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLELV---EPFV--TDMERVKTITDLRKGQI 228
GT + APE ++ + +DM+S+G+I LV PF+ D E + +T
Sbjct: 167 FGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFD 226
Query: 227 PAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAK 57
I L+++ RLD Q L+ + + K+ + L ++ K
Sbjct: 227 DEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKK 283
>X59727-1|CAA42411.1| 557|Homo sapiens 63kDa protein kinase
protein.
Length = 557
Score = 64.9 bits (151), Expect = 3e-10
Identities = 38/94 (40%), Positives = 57/94 (60%), Gaps = 7/94 (7%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ--SHSGL---AL 387
QL+RGL YIHS ++H D+KP+N+F++ + L++++GDFGLA + Q SH G L
Sbjct: 132 QLLRGLKYIHSANVLHRDLKPANIFISTED--LVLKIGDFGLARIVDQHYSHKGYLSEGL 189
Query: 386 GTHMYAAPEQLDGQCN--PKSDMYSLGIILLELV 291
T Y +P L N DM++ G IL E++
Sbjct: 190 VTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEML 223
>U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase
protein.
Length = 1914
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 7/177 (3%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHS-GLA 390
I Q+ G+ YIH +GI+H D+KP N+ + ++ G ++L DFGLA L+ + S +
Sbjct: 1563 IKYMRQISEGVEYIHKQGIVHLDLKPENI-MCVNKTGTRIKLIDFGLARRLENAGSLKVL 1621
Query: 389 LGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLELV---EPFV--TDMERVKTITDLRKGQI 228
GT + APE ++ + +DM+S+G+I LV PF+ D E + +T
Sbjct: 1622 FGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFD 1681
Query: 227 PAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAK 57
I L+++ RLD Q L+ + + K+ + L ++ K
Sbjct: 1682 DEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKK 1738
>BC117216-1|AAI17217.1| 587|Homo sapiens mitogen-activated protein
kinase 4 protein.
Length = 587
Score = 64.9 bits (151), Expect = 3e-10
Identities = 38/94 (40%), Positives = 57/94 (60%), Gaps = 7/94 (7%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ--SHSGL---AL 387
QL+RGL YIHS ++H D+KP+N+F++ + L++++GDFGLA + Q SH G L
Sbjct: 132 QLLRGLKYIHSANVLHRDLKPANIFISTED--LVLKIGDFGLARIVDQHYSHKGYLSEGL 189
Query: 386 GTHMYAAPEQLDGQCN--PKSDMYSLGIILLELV 291
T Y +P L N DM++ G IL E++
Sbjct: 190 VTKWYRSPRLLLSPNNYTKAIDMWAAGCILAEML 223
>AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain
kinase protein.
Length = 1914
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 7/177 (3%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHS-GLA 390
I Q+ G+ YIH +GI+H D+KP N+ + ++ G ++L DFGLA L+ + S +
Sbjct: 1563 IKYMRQISEGVEYIHKQGIVHLDLKPENI-MCVNKTGTRIKLIDFGLARRLENAGSLKVL 1621
Query: 389 LGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLELV---EPFV--TDMERVKTITDLRKGQI 228
GT + APE ++ + +DM+S+G+I LV PF+ D E + +T
Sbjct: 1622 FGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFD 1681
Query: 227 PAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAK 57
I L+++ RLD Q L+ + + K+ + L ++ K
Sbjct: 1682 DEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKK 1738
>AK222703-1|BAD96423.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase IIB isoform
2 variant protein.
Length = 542
Score = 64.9 bits (151), Expect = 3e-10
Identities = 56/197 (28%), Positives = 99/197 (50%), Gaps = 16/197 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPL---QQSHSGLALGT 381
Q++ + + H G++H D+KP N+ +A G V+L DFGLA + QQ+ G A GT
Sbjct: 119 QILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFA-GT 177
Query: 380 HMYAAPEQLDGQCNPKS-DMYSLGIILLELV--EPFVTDMERVKTITDLRKG--QIPA-H 219
Y +PE L + K D+++ G+IL L+ P D ++ K ++ G P+
Sbjct: 178 PGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPE 237
Query: 218 LTANYPKIAHIIGKLVQRKPSKRLDTAQLLE-----ELKTLAE--NKDDTIRSLREELAA 60
P+ ++I +++ P+KR+ + L+ + T+A + +T+ L++ A
Sbjct: 238 WDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMYRQETVECLKKFNAR 297
Query: 59 KDDEIAKLKMMLANLNF 9
+ + A L MLA NF
Sbjct: 298 RKLKGAILTTMLATRNF 314
>AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kinase
isoform 2 protein.
Length = 1845
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 7/177 (3%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHS-GLA 390
I Q+ G+ YIH +GI+H D+KP N+ + ++ G ++L DFGLA L+ + S +
Sbjct: 1494 IKYMRQISEGVEYIHKQGIVHLDLKPENI-MCVNKTGTRIKLIDFGLARRLENAGSLKVL 1552
Query: 389 LGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLELV---EPFV--TDMERVKTITDLRKGQI 228
GT + APE ++ + +DM+S+G+I LV PF+ D E + +T
Sbjct: 1553 FGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFD 1612
Query: 227 PAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAK 57
I L+++ RLD Q L+ + + K+ + L ++ K
Sbjct: 1613 DEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKK 1669
>AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kinase
protein.
Length = 992
Score = 64.9 bits (151), Expect = 3e-10
Identities = 49/177 (27%), Positives = 84/177 (47%), Gaps = 7/177 (3%)
Frame = -1
Query: 566 IDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHS-GLA 390
I Q+ G+ YIH +GI+H D+KP N+ + ++ G ++L DFGLA L+ + S +
Sbjct: 641 IKYMRQISEGVEYIHKQGIVHLDLKPENI-MCVNKTGTRIKLIDFGLARRLENAGSLKVL 699
Query: 389 LGTHMYAAPEQLDGQ-CNPKSDMYSLGIILLELV---EPFV--TDMERVKTITDLRKGQI 228
GT + APE ++ + +DM+S+G+I LV PF+ D E + +T
Sbjct: 700 FGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFD 759
Query: 227 PAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAK 57
I L+++ RLD Q L+ + + K+ + L ++ K
Sbjct: 760 DEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKK 816
>BC050299-1|AAH50299.1| 587|Homo sapiens mitogen-activated protein
kinase 4 protein.
Length = 587
Score = 64.5 bits (150), Expect = 4e-10
Identities = 38/94 (40%), Positives = 57/94 (60%), Gaps = 7/94 (7%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ--SHSGL---AL 387
QL+RGL YIHS ++H D+KP+N+F++ + L++++GDFGLA + Q SH G L
Sbjct: 132 QLLRGLKYIHSANVLHRDLKPANIFISTED--LVLKIGDFGLARIVDQHYSHKGYLSEGL 189
Query: 386 GTHMYAAPEQLDGQCN--PKSDMYSLGIILLELV 291
T Y +P L N DM++ G IL E++
Sbjct: 190 VTKWYRSPRLLLSPNNYTKAIDMWAAGCILSEML 223
>BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 298 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 354
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 355 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 401
>AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor
associated kinase-4 protein.
Length = 460
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 298 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 354
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 355 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 401
>AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 4
protein.
Length = 336
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 174 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 230
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 231 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 277
>AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 3
protein.
Length = 336
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 174 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 230
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 231 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 277
>AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 2
protein.
Length = 336
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 174 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 230
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 231 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 277
>AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1
receptor-associated kinase 4 short form variant 1
protein.
Length = 336
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 174 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 230
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 231 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 277
>AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 variant protein.
Length = 460
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 298 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 354
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 355 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 401
>AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 298 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 354
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 355 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 401
>AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1
receptor-associated kinase 4 protein.
Length = 460
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 298 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 354
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 355 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 401
>AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens
cDNA FLJ14395 fis, clone HEMBA1003250, weakly similar to
PROTEIN KINASE APK1A (EC 2.7.1.-). ).
Length = 277
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 174 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 230
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 231 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 277
>AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens
cDNA FLJ20521 fis, clone KAT10395. ).
Length = 460
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 298 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 354
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 355 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 401
>AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor
associated kinase 4 protein.
Length = 460
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 298 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 354
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 355 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 401
>AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase
NY-REN-64 antigen protein.
Length = 460
Score = 64.5 bits (150), Expect = 4e-10
Identities = 35/107 (32%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Frame = -1
Query: 539 GLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACP----LQQSHSGLALGTHMY 372
G++++H IH DIK +N+ + + ++ DFGLA Q + +GT Y
Sbjct: 298 GINFLHENHHIHRDIKSANILL---DEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAY 354
Query: 371 AAPEQLDGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRK 237
APE L G+ PKSD+YS G++LLE++ P V + + + D+++
Sbjct: 355 MAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKE 401
>CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein.
Length = 586
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 371 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 430
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 431 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 490
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 491 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 546
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 547 ESTALPQVLA 556
>BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein.
Length = 1001
Score = 64.1 bits (149), Expect = 5e-10
Identities = 52/186 (27%), Positives = 95/186 (51%), Gaps = 12/186 (6%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH DIK N+ + E G V+L DFG A ++S +GT + A
Sbjct: 136 LQGLAYLHSHTMIHRDIKAGNILLT--EPG-QVKLADFGSASMASPANS--FVGTPYWMA 190
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + +
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNEW 250
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKD----DTIRSLREELAAKDD-EIA 42
+ + +Q+ P R + +LL+ + L E + D I+ ++ + D+ +
Sbjct: 251 SDYFRNFVDSCLQKIPQDRPTSEELLKHIFVLRERPETVLIDLIQRTKDAVRELDNLQYR 310
Query: 41 KLKMML 24
K+K +L
Sbjct: 311 KMKKLL 316
>BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 387
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 388 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 447
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 448 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 503
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 504 ESTALPQVLA 513
>AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 387
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 388 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 447
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 448 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 503
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 504 ESTALPQVLA 513
>AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2
transcript variant del2-3 protein.
Length = 452
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 237 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 296
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 297 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 356
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 357 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 412
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 413 ESTALPQVLA 422
>AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2
transcript variant insX protein.
Length = 586
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 371 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 430
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 431 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 490
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 491 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 546
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 547 ESTALPQVLA 556
>AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase
TAO1 protein.
Length = 1001
Score = 64.1 bits (149), Expect = 5e-10
Identities = 52/186 (27%), Positives = 95/186 (51%), Gaps = 12/186 (6%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH DIK N+ + E G V+L DFG A ++S +GT + A
Sbjct: 136 LQGLAYLHSHTMIHRDIKAGNILLT--EPG-QVKLADFGSASMASPANS--FVGTPYWMA 190
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + +
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNEW 250
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKD----DTIRSLREELAAKDD-EIA 42
+ + +Q+ P R + +LL+ + L E + D I+ ++ + D+ +
Sbjct: 251 SDYFRNFVDSCLQKIPQDRPTSEELLKHIFVLRERPETVLIDLIQRTKDAVRELDNLQYR 310
Query: 41 KLKMML 24
K+K +L
Sbjct: 311 KMKKLL 316
>AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 387
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 388 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 447
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 448 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 503
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 504 ESTALPQVLA 513
>AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog
(S. pombe) protein.
Length = 543
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 387
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 388 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 447
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 448 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 503
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 504 ESTALPQVLA 513
>AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein.
Length = 543
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 387
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 388 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 447
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 448 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 503
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 504 ESTALPQVLA 513
>AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein.
Length = 322
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 107 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 166
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 167 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 226
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 227 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 282
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 283 ESTALPQVLA 292
>AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2
protein.
Length = 543
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 387
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 388 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 447
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 448 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 503
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 504 ESTALPQVLA 513
>AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein.
Length = 543
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 387
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 388 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 447
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 448 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 503
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 504 ESTALPQVLA 513
>AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2
protein.
Length = 543
Score = 64.1 bits (149), Expect = 5e-10
Identities = 54/190 (28%), Positives = 87/190 (45%), Gaps = 11/190 (5%)
Frame = -1
Query: 557 FTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLAL-GT 381
F Q++ + Y+H GIIH D+KP NV ++ E L+++ DFG + L ++ L GT
Sbjct: 328 FYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGETSLMRTLCGT 387
Query: 380 HMYAAPEQL----DGQCNPKSDMYSLGIIL---LELVEPFVTDMERVKTITDLRKGQ--- 231
Y APE L N D +SLG+IL L PF +V + G+
Sbjct: 388 PTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLKDQITSGKYNF 447
Query: 230 IPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKDDTIRSLREELAAKDD 51
IP K ++ KL+ P R T + L +D+ ++ ++L ++++
Sbjct: 448 IPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRH----PWLQDEDMKRKFQDLLSEEN 503
Query: 50 EIAKLKMMLA 21
E L +LA
Sbjct: 504 ESTALPQVLA 513
>AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein.
Length = 1005
Score = 64.1 bits (149), Expect = 5e-10
Identities = 52/186 (27%), Positives = 95/186 (51%), Gaps = 12/186 (6%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH DIK N+ + E G V+L DFG A ++S +GT + A
Sbjct: 140 LQGLAYLHSHTMIHRDIKAGNILLT--EPG-QVKLADFGSASMASPANS--FVGTPYWMA 194
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + +
Sbjct: 195 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNEW 254
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKD----DTIRSLREELAAKDD-EIA 42
+ + +Q+ P R + +LL+ + L E + D I+ ++ + D+ +
Sbjct: 255 SDYFRNFVDSCLQKIPQDRPTSEELLKHIFVLRERPETVLIDLIQRTKDAVRELDNLQYR 314
Query: 41 KLKMML 24
K+K +L
Sbjct: 315 KMKKLL 320
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 63.7 bits (148), Expect = 6e-10
Identities = 45/149 (30%), Positives = 79/149 (53%), Gaps = 8/149 (5%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLA-LGTHM 375
QLV GLHY+HS G++H DIKPSN+ + H +++ DFG A + + + G+
Sbjct: 1186 QLVEGLHYLHSHGVLHLDIKPSNILMV-HPAREDIKICDFGFAQNITPAELQFSQYGSPE 1244
Query: 374 YAAPEQL-DGQCNPKSDMYSLGII---LLELVEPFVTDMERVKTITDLRKGQI--PAHLT 213
+ +PE + + SD++++G+I L PF + +R T+ ++ +G++ + +
Sbjct: 1245 FVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSPFAGESDRA-TLLNVLEGRVSWSSPMA 1303
Query: 212 ANYPKIA-HIIGKLVQRKPSKRLDTAQLL 129
A+ + A I +QR P R AQ L
Sbjct: 1304 AHLSEDAKDFIKATLQRAPQARPSAAQCL 1332
Score = 35.5 bits (78), Expect = 0.19
Identities = 34/144 (23%), Positives = 67/144 (46%), Gaps = 4/144 (2%)
Frame = -1
Query: 647 LPLHVCESPIEAKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAP 468
L L +C P + AS + ++ D Q++ Y+H++ I+H D++ N+ +
Sbjct: 2359 LILELCSGPELLPCLAERASYSESEVK-DYLWQMLSATQYLHNQHILHLDLRSENMIITE 2417
Query: 467 HEGGLLVQLGDFGLACPLQQSHSGLALGTHMY-AAPEQLDGQ-CNPKSDMYSLGI-ILLE 297
+ L+++ D G A L Q + Y E L+GQ P++D++++G+ +
Sbjct: 2418 YN---LLKVVDLGNAQSLSQEKVLPSDKFKDYLETMELLEGQGAVPQTDIWAIGVTAFIM 2474
Query: 296 LVEPFVTDMERVKTI-TDLRKGQI 228
L + E + + LRKG +
Sbjct: 2475 LSAEYPVSSEGARDLQRGLRKGLV 2498
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 63.7 bits (148), Expect = 6e-10
Identities = 45/149 (30%), Positives = 79/149 (53%), Gaps = 8/149 (5%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLA-LGTHM 375
QLV GLHY+HS G++H DIKPSN+ + H +++ DFG A + + + G+
Sbjct: 1186 QLVEGLHYLHSHGVLHLDIKPSNILMV-HPAREDIKICDFGFAQNITPAELQFSQYGSPE 1244
Query: 374 YAAPEQL-DGQCNPKSDMYSLGII---LLELVEPFVTDMERVKTITDLRKGQI--PAHLT 213
+ +PE + + SD++++G+I L PF + +R T+ ++ +G++ + +
Sbjct: 1245 FVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSPFAGESDRA-TLLNVLEGRVSWSSPMA 1303
Query: 212 ANYPKIA-HIIGKLVQRKPSKRLDTAQLL 129
A+ + A I +QR P R AQ L
Sbjct: 1304 AHLSEDAKDFIKATLQRAPQARPSAAQCL 1332
Score = 35.5 bits (78), Expect = 0.19
Identities = 34/144 (23%), Positives = 67/144 (46%), Gaps = 4/144 (2%)
Frame = -1
Query: 647 LPLHVCESPIEAKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAP 468
L L +C P + AS + ++ D Q++ Y+H++ I+H D++ N+ +
Sbjct: 2359 LILELCSGPELLPCLAERASYSESEVK-DYLWQMLSATQYLHNQHILHLDLRSENMIITE 2417
Query: 467 HEGGLLVQLGDFGLACPLQQSHSGLALGTHMY-AAPEQLDGQ-CNPKSDMYSLGI-ILLE 297
+ L+++ D G A L Q + Y E L+GQ P++D++++G+ +
Sbjct: 2418 YN---LLKVVDLGNAQSLSQEKVLPSDKFKDYLETMELLEGQGAVPQTDIWAIGVTAFIM 2474
Query: 296 LVEPFVTDMERVKTI-TDLRKGQI 228
L + E + + LRKG +
Sbjct: 2475 LSAEYPVSSEGARDLQRGLRKGLV 2498
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 63.7 bits (148), Expect = 6e-10
Identities = 46/129 (35%), Positives = 65/129 (50%), Gaps = 8/129 (6%)
Frame = -1
Query: 575 DLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHS- 399
DL F Q+V + Y H ++H D+KP NV +G LV+L DFG + Q
Sbjct: 114 DLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQG--LVKLTDFGFSNKFQPGKKL 171
Query: 398 GLALGTHMYAAPEQL--DGQCNPKSDMYSLGIILLELV---EPF--VTDMERVKTITDLR 240
+ G+ Y+APE L D P D++SLG+IL LV PF D E + I D
Sbjct: 172 TTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCEQPPFQEANDSETLTMIMDC- 230
Query: 239 KGQIPAHLT 213
K +P+H++
Sbjct: 231 KYTVPSHVS 239
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 63.7 bits (148), Expect = 6e-10
Identities = 45/149 (30%), Positives = 79/149 (53%), Gaps = 8/149 (5%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLA-LGTHM 375
QLV GLHY+HS G++H DIKPSN+ + H +++ DFG A + + + G+
Sbjct: 1186 QLVEGLHYLHSHGVLHLDIKPSNILMV-HPAREDIKICDFGFAQNITPAELQFSQYGSPE 1244
Query: 374 YAAPEQL-DGQCNPKSDMYSLGII---LLELVEPFVTDMERVKTITDLRKGQI--PAHLT 213
+ +PE + + SD++++G+I L PF + +R T+ ++ +G++ + +
Sbjct: 1245 FVSPEIIQQNPVSEASDIWAMGVISYLSLTCSSPFAGESDRA-TLLNVLEGRVSWSSPMA 1303
Query: 212 ANYPKIA-HIIGKLVQRKPSKRLDTAQLL 129
A+ + A I +QR P R AQ L
Sbjct: 1304 AHLSEDAKDFIKATLQRAPQARPSAAQCL 1332
Score = 39.1 bits (87), Expect = 0.015
Identities = 36/146 (24%), Positives = 68/146 (46%), Gaps = 6/146 (4%)
Frame = -1
Query: 647 LPLHVCESPIEAKDITFPASINHIDLLIDMFTQLVRGLHYIHSRGIIHHDIKPSNVFVAP 468
L L +C P + AS + ++ D Q++ Y+H++ I+H D++ N+ +
Sbjct: 2359 LILELCSGPELLPCLAERASYSESEVK-DYLWQMLSATQYLHNQHILHLDLRSENMIITE 2417
Query: 467 HEGGLLVQLGDFGLACPLQQSH---SGLALGTHMYAAPEQLDGQ-CNPKSDMYSLGI-IL 303
+ L+++ D G A L Q S APE L+GQ P++D++++G+
Sbjct: 2418 YN---LLKVVDLGNAQSLSQEKVLPSDKFKDYLETMAPELLEGQGAVPQTDIWAIGVTAF 2474
Query: 302 LELVEPFVTDMERVKTI-TDLRKGQI 228
+ L + E + + LRKG +
Sbjct: 2475 IMLSAEYPVSSEGARDLQRGLRKGLV 2500
>U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine
protein kinase PRK protein.
Length = 607
Score = 63.3 bits (147), Expect = 8e-10
Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 7/148 (4%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ--QSHSGLALGTH 378
Q++ GL Y+H RGI+H D+K N F+ + + +++GDFGLA L+ + GT
Sbjct: 129 QILSGLKYLHQRGILHRDLKLGNFFITEN---MELKVGDFGLAARLEPPEQRKKTICGTP 185
Query: 377 MYAAPEQLDGQCN-PKSDMYSLGIILLELV---EPFVT-DMERVKTITDLRKGQIPAHLT 213
Y APE L Q + P++D++SLG ++ L+ PF T D++ +PA L+
Sbjct: 186 NYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLS 245
Query: 212 ANYPKIAHIIGKLVQRKPSKRLDTAQLL 129
++ +++ P R Q+L
Sbjct: 246 L---PARQLLAAILRASPRDRPSIDQIL 270
>BC064543-1|AAH64543.1| 847|Homo sapiens mitogen-activated protein
kinase kinase kinase 11 protein.
Length = 847
Score = 63.3 bits (147), Expect = 8e-10
Identities = 59/207 (28%), Positives = 101/207 (48%), Gaps = 23/207 (11%)
Frame = -1
Query: 572 LLIDMFTQLVRGLHYIHSRG---IIHHDIKPSNVFVAPH-EGGLL----VQLGDFGLACP 417
+L++ Q+ RG+HY+H +IH D+K +N+ + H E + +++ DFGLA
Sbjct: 214 VLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNILLLQHIESDDMEHKTLKITDFGLARE 273
Query: 416 LQQSHSGLALGTHMYAAPEQLDGQCNPK-SDMYSLGIILLELVEPFV----TDMERVKTI 252
++ A GT+ + APE + K SD++S G++L EL+ V D V
Sbjct: 274 WHKTTQMSAAGTYAWMAPEVIKASTFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYG 333
Query: 251 TDLRKGQIPAHLTANYPKIAHIIGKLVQRKPSKRLDTAQLLEEL-----KTLAENKDDTI 87
+ K +P T P A ++ + P +R D A +L++L + L E D+
Sbjct: 334 VAVNKLTLPIPSTCPEP-FAQLMADCWAQDPHRRPDFASILQQLEALEAQVLREMPRDSF 392
Query: 86 RSLRE----ELAAKDDEI-AKLKMMLA 21
S++E E+ DE+ AK K +L+
Sbjct: 393 HSMQEGWKREIQGLFDELRAKEKELLS 419
>BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 63.3 bits (147), Expect = 8e-10
Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 7/148 (4%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ--QSHSGLALGTH 378
Q++ GL Y+H RGI+H D+K N F+ + + +++GDFGLA L+ + GT
Sbjct: 168 QILSGLKYLHQRGILHRDLKLGNFFITEN---MELKVGDFGLAARLEPPEQRKKTICGTP 224
Query: 377 MYAAPEQLDGQCN-PKSDMYSLGIILLELV---EPFVT-DMERVKTITDLRKGQIPAHLT 213
Y APE L Q + P++D++SLG ++ L+ PF T D++ +PA L+
Sbjct: 225 NYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLS 284
Query: 212 ANYPKIAHIIGKLVQRKPSKRLDTAQLL 129
++ +++ P R Q+L
Sbjct: 285 L---PARQLLAAILRASPRDRPSIDQIL 309
>AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 63.3 bits (147), Expect = 8e-10
Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 7/148 (4%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ--QSHSGLALGTH 378
Q++ GL Y+H RGI+H D+K N F+ + + +++GDFGLA L+ + GT
Sbjct: 168 QILSGLKYLHQRGILHRDLKLGNFFITEN---MELKVGDFGLAARLEPPEQRKKTICGTP 224
Query: 377 MYAAPEQLDGQCN-PKSDMYSLGIILLELV---EPFVT-DMERVKTITDLRKGQIPAHLT 213
Y APE L Q + P++D++SLG ++ L+ PF T D++ +PA L+
Sbjct: 225 NYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLS 284
Query: 212 ANYPKIAHIIGKLVQRKPSKRLDTAQLL 129
++ +++ P R Q+L
Sbjct: 285 L---PARQLLAAILRASPRDRPSIDQIL 309
>AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 63.3 bits (147), Expect = 8e-10
Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 7/148 (4%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ--QSHSGLALGTH 378
Q++ GL Y+H RGI+H D+K N F+ + + +++GDFGLA L+ + GT
Sbjct: 168 QILSGLKYLHQRGILHRDLKLGNFFITEN---MELKVGDFGLAARLEPPEQRKKTICGTP 224
Query: 377 MYAAPEQLDGQCN-PKSDMYSLGIILLELV---EPFVT-DMERVKTITDLRKGQIPAHLT 213
Y APE L Q + P++D++SLG ++ L+ PF T D++ +PA L+
Sbjct: 225 NYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLS 284
Query: 212 ANYPKIAHIIGKLVQRKPSKRLDTAQLL 129
++ +++ P R Q+L
Sbjct: 285 L---PARQLLAAILRASPRDRPSIDQIL 309
>AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine
protein kinase protein.
Length = 646
Score = 63.3 bits (147), Expect = 8e-10
Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 7/148 (4%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ--QSHSGLALGTH 378
Q++ GL Y+H RGI+H D+K N F+ + + +++GDFGLA L+ + GT
Sbjct: 168 QILSGLKYLHQRGILHRDLKLGNFFITEN---MELKVGDFGLAARLEPPEQRKKTICGTP 224
Query: 377 MYAAPEQLDGQCN-PKSDMYSLGIILLELV---EPFVT-DMERVKTITDLRKGQIPAHLT 213
Y APE L Q + P++D++SLG ++ L+ PF T D++ +PA L+
Sbjct: 225 NYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLS 284
Query: 212 ANYPKIAHIIGKLVQRKPSKRLDTAQLL 129
++ +++ P R Q+L
Sbjct: 285 L---PARQLLAAILRASPRDRPSIDQIL 309
>AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein.
Length = 1001
Score = 63.3 bits (147), Expect = 8e-10
Identities = 52/186 (27%), Positives = 95/186 (51%), Gaps = 12/186 (6%)
Frame = -1
Query: 545 VRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYAA 366
++GL Y+HS +IH DIK N+ + E G V+L DFG A ++S +GT + A
Sbjct: 136 LQGLAYLHSHTMIHRDIKAGNILLT--EPG-QVKLADFGSASMASPANS--FVGTPYWMA 190
Query: 365 PEQL----DGQCNPKSDMYSLGIILLELVE--PFVTDMERVKTITDLRKGQIPAHLTANY 204
PE + +GQ + K D++SLGI +EL E P + +M + + + + + P + +
Sbjct: 191 PEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNEW 250
Query: 203 PK-IAHIIGKLVQRKPSKRLDTAQLLEELKTLAENKD----DTIRSLREELAAKDD-EIA 42
+ + +Q+ P R + +LL+ + L E + D I+ ++ + D+ +
Sbjct: 251 SDYFRNSVDSCLQKIPQDRPTSEELLKHIFVLRERPETVLIDLIQRTKDAVRELDNLQYR 310
Query: 41 KLKMML 24
K+K +L
Sbjct: 311 KMKKLL 316
>AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 variant
protein.
Length = 621
Score = 63.3 bits (147), Expect = 8e-10
Identities = 45/148 (30%), Positives = 76/148 (51%), Gaps = 7/148 (4%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQ--QSHSGLALGTH 378
Q++ GL Y+H RGI+H D+K N F+ + + +++GDFGLA L+ + GT
Sbjct: 143 QILSGLKYLHQRGILHRDLKLGNFFITEN---MELKVGDFGLAARLEPPEQRKKTICGTP 199
Query: 377 MYAAPEQLDGQCN-PKSDMYSLGIILLELV---EPFVT-DMERVKTITDLRKGQIPAHLT 213
Y APE L Q + P++D++SLG ++ L+ PF T D++ +PA L+
Sbjct: 200 NYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLS 259
Query: 212 ANYPKIAHIIGKLVQRKPSKRLDTAQLL 129
++ +++ P R Q+L
Sbjct: 260 L---PARQLLAAILRASPRDRPSIDQIL 284
>X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein.
Length = 603
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 8/151 (5%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ--SHSGLALGTH 378
Q+V G Y+H +IH D+K N+F+ L V++GDFGLA ++ GT
Sbjct: 159 QIVLGCQYLHRNRVIHRDLKLGNLFL---NEDLEVKIGDFGLATKVEYDGERKKTLCGTP 215
Query: 377 MYAAPEQLDGQCNP-KSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQ--IPAHL 216
Y APE L + + + D++S+G I+ L+ PF T + +T ++K + IP H+
Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLK-ETYLRIKKNEYSIPKHI 274
Query: 215 TANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
P A +I K++Q P+ R +LL +
Sbjct: 275 N---PVAASLIQKMLQTDPTARPTINELLND 302
>U71088-1|AAB16852.2| 444|Homo sapiens MAP kinase kinase MEK5c
protein.
Length = 444
Score = 62.9 bits (146), Expect = 1e-09
Identities = 43/143 (30%), Positives = 77/143 (53%), Gaps = 3/143 (2%)
Frame = -1
Query: 548 LVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYA 369
+V+GL Y+ S I+H D+KPSN+ V V+L DFG++ L S + +GT+ Y
Sbjct: 267 VVKGLTYLWSLKILHRDVKPSNMLVNTRG---QVKLCDFGVSTQLVNSIAKTYVGTNAYM 323
Query: 368 APEQLDG-QCNPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHLTANYPK 198
APE++ G Q SD++SLGI +E+ + + ++ ++ I D +P +
Sbjct: 324 APERISGEQYGIHSDVWSLGISFMEIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSE--P 381
Query: 197 IAHIIGKLVQRKPSKRLDTAQLL 129
H I + ++++P +R +L+
Sbjct: 382 FVHFITQCMRKQPKERPAPEELM 404
>U25265-1|AAA96146.1| 438|Homo sapiens MEK5 protein.
Length = 438
Score = 62.9 bits (146), Expect = 1e-09
Identities = 43/143 (30%), Positives = 77/143 (53%), Gaps = 3/143 (2%)
Frame = -1
Query: 548 LVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSGLALGTHMYA 369
+V+GL Y+ S I+H D+KPSN+ V V+L DFG++ L S + +GT+ Y
Sbjct: 267 VVKGLTYLWSLKILHRDVKPSNMLVNTRG---QVKLCDFGVSTQLVNSIAKTYVGTNAYM 323
Query: 368 APEQLDG-QCNPKSDMYSLGIILLELV--EPFVTDMERVKTITDLRKGQIPAHLTANYPK 198
APE++ G Q SD++SLGI +E+ + + ++ ++ I D +P +
Sbjct: 324 APERISGEQYGIHSDVWSLGISFMEIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSE--P 381
Query: 197 IAHIIGKLVQRKPSKRLDTAQLL 129
H I + ++++P +R +L+
Sbjct: 382 FVHFITQCMRKQPKERPAPEELM 404
>U01038-1|AAA56634.1| 603|Homo sapiens pLK protein.
Length = 603
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 8/151 (5%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ--SHSGLALGTH 378
Q+V G Y+H +IH D+K N+F+ L V++GDFGLA ++ GT
Sbjct: 159 QIVLGCQYLHRNRVIHRDLKLGNLFL---NEDLEVKIGDFGLATKVEYDGERKKTLCGTP 215
Query: 377 MYAAPEQLDGQCNP-KSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQ--IPAHL 216
Y APE L + + + D++S+G I+ L+ PF T + +T ++K + IP H+
Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLK-ETYLRIKKNEYSIPKHI 274
Query: 215 TANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
P A +I K++Q P+ R +LL +
Sbjct: 275 N---PVAASLIQKMLQTDPTARPTINELLND 302
>D50863-1|BAA09459.1| 626|Homo sapiens TESK1 protein.
Length = 626
Score = 62.9 bits (146), Expect = 1e-09
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 7/119 (5%)
Frame = -1
Query: 548 LVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG------LAL 387
+ RGL Y+HS+G+ H D+ N V + G +GDFGLA + G +
Sbjct: 159 IARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVV 218
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLT 213
G+ + APE L G+ + K+D+++ GI+L EL+ D + + D +PA T
Sbjct: 219 GSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGL-DVPAFRT 276
>BC067130-1|AAH67130.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 62.9 bits (146), Expect = 1e-09
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 7/119 (5%)
Frame = -1
Query: 548 LVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG------LAL 387
+ RGL Y+HS+G+ H D+ N V + G +GDFGLA + G +
Sbjct: 159 IARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVV 218
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLT 213
G+ + APE L G+ + K+D+++ GI+L EL+ D + + D +PA T
Sbjct: 219 GSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGL-DVPAFRT 276
>BC038448-1|AAH38448.1| 626|Homo sapiens TESK1 protein protein.
Length = 626
Score = 62.9 bits (146), Expect = 1e-09
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 7/119 (5%)
Frame = -1
Query: 548 LVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG------LAL 387
+ RGL Y+HS+G+ H D+ N V + G +GDFGLA + G +
Sbjct: 159 IARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVV 218
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLT 213
G+ + APE L G+ + K+D+++ GI+L EL+ D + + D +PA T
Sbjct: 219 GSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGL-DVPAFRT 276
>BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein.
Length = 1036
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/148 (26%), Positives = 76/148 (51%), Gaps = 12/148 (8%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVA------PHEGGLLVQLGDFGLACPLQQSHSGLA 390
Q+ + +HS+GIIH D+KP N+ ++ G+ +++ DFG A L +
Sbjct: 114 QIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSSVSGIRIKIADFGFARYLHSNMMAAT 173
Query: 389 L-GTHMYAAPEQLDGQ-CNPKSDMYSLGIILLELV---EPF-VTDMERVKTITDLRKGQI 228
L G+ MY APE + Q + K+D++S+G ++ + + PF + ++ + + +
Sbjct: 174 LCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLM 233
Query: 227 PAHLTANYPKIAHIIGKLVQRKPSKRLD 144
P+ P +A+++ L+QR R+D
Sbjct: 234 PSIPRETSPYLANLLLGLLQRNQKDRMD 261
>BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 8/151 (5%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ--SHSGLALGTH 378
Q+V G Y+H +IH D+K N+F+ L V++GDFGLA ++ GT
Sbjct: 159 QIVLGCQYLHRNRVIHRDLKLGNLFL---NEDLEVKIGDFGLATKVEYDGERKKTLCGTP 215
Query: 377 MYAAPEQLDGQCNP-KSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQ--IPAHL 216
Y APE L + + + D++S+G I+ L+ PF T + +T ++K + IP H+
Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLK-ETYLRIKKNEYSIPKHI 274
Query: 215 TANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
P A +I K++Q P+ R +LL +
Sbjct: 275 N---PVAASLIQKMLQTDPTARPTINELLND 302
>BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 8/151 (5%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ--SHSGLALGTH 378
Q+V G Y+H +IH D+K N+F+ L V++GDFGLA ++ GT
Sbjct: 159 QIVLGCQYLHRNRVIHRDLKLGNLFL---NEDLEVKIGDFGLATKVEYDGERKKTLCGTP 215
Query: 377 MYAAPEQLDGQCNP-KSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQ--IPAHL 216
Y APE L + + + D++S+G I+ L+ PF T + +T ++K + IP H+
Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLK-ETYLRIKKNEYSIPKHI 274
Query: 215 TANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
P A +I K++Q P+ R +LL +
Sbjct: 275 N---PVAASLIQKMLQTDPTARPTINELLND 302
>BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 8/151 (5%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ--SHSGLALGTH 378
Q+V G Y+H +IH D+K N+F+ L V++GDFGLA ++ GT
Sbjct: 159 QIVLGCQYLHRNRVIHRDLKLGNLFL---NEDLEVKIGDFGLATKVEYDGERKKTLCGTP 215
Query: 377 MYAAPEQLDGQCNP-KSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQ--IPAHL 216
Y APE L + + + D++S+G I+ L+ PF T + +T ++K + IP H+
Sbjct: 216 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLK-ETYLRIKKNEYSIPKHI 274
Query: 215 TANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
P A +I K++Q P+ R +LL +
Sbjct: 275 N---PVAASLIQKMLQTDPTARPTINELLND 302
>AL357874-1|CAI13441.1| 626|Homo sapiens testis-specific kinase 1
protein.
Length = 626
Score = 62.9 bits (146), Expect = 1e-09
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 7/119 (5%)
Frame = -1
Query: 548 LVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG------LAL 387
+ RGL Y+HS+G+ H D+ N V + G +GDFGLA + G +
Sbjct: 159 IARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVV 218
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLT 213
G+ + APE L G+ + K+D+++ GI+L EL+ D + + D +PA T
Sbjct: 219 GSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGL-DVPAFRT 276
>AF507907-1|AAM50515.1| 244|Homo sapiens testis-specific kinase-1
protein.
Length = 244
Score = 62.9 bits (146), Expect = 1e-09
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 7/119 (5%)
Frame = -1
Query: 548 LVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQSHSG------LAL 387
+ RGL Y+HS+G+ H D+ N V + G +GDFGLA + G +
Sbjct: 75 IARGLRYLHSKGVFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKIPVYREGARKEPLAVV 134
Query: 386 GTHMYAAPEQLDGQC-NPKSDMYSLGIILLELVEPFVTDMERVKTITDLRKGQIPAHLT 213
G+ + APE L G+ + K+D+++ GI+L EL+ D + + D +PA T
Sbjct: 135 GSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGL-DVPAFRT 192
>AB209179-1|BAD92416.1| 546|Homo sapiens polo-like kinase variant
protein.
Length = 546
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/151 (31%), Positives = 78/151 (51%), Gaps = 8/151 (5%)
Frame = -1
Query: 551 QLVRGLHYIHSRGIIHHDIKPSNVFVAPHEGGLLVQLGDFGLACPLQQ--SHSGLALGTH 378
Q+V G Y+H +IH D+K N+F+ L V++GDFGLA ++ GT
Sbjct: 102 QIVLGCQYLHRNRVIHRDLKLGNLFL---NEDLEVKIGDFGLATKVEYDGERKKTLCGTP 158
Query: 377 MYAAPEQLDGQCNP-KSDMYSLGIILLELV---EPFVTDMERVKTITDLRKGQ--IPAHL 216
Y APE L + + + D++S+G I+ L+ PF T + +T ++K + IP H+
Sbjct: 159 NYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLK-ETYLRIKKNEYSIPKHI 217
Query: 215 TANYPKIAHIIGKLVQRKPSKRLDTAQLLEE 123
P A +I K++Q P+ R +LL +
Sbjct: 218 N---PVAASLIQKMLQTDPTARPTINELLND 245
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,234,107
Number of Sequences: 237096
Number of extensions: 2986312
Number of successful extensions: 11040
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 9576
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10381
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8343197486
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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