Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmte12m04
(746 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 199 1e-50
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 199 1e-50
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 199 1e-50
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 199 1e-50
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 196 7e-50
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 196 7e-50
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 196 7e-50
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 182 2e-45
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 182 2e-45
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 182 2e-45
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 182 2e-45
BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein. 178 2e-44
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 178 2e-44
AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens ... 168 2e-41
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 158 2e-38
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 153 6e-37
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 153 6e-37
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 153 6e-37
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 153 6e-37
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 153 6e-37
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 152 1e-36
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 152 1e-36
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 152 1e-36
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 152 1e-36
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 152 1e-36
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 152 1e-36
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 151 2e-36
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 151 2e-36
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 151 2e-36
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 151 2e-36
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 149 1e-35
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 149 1e-35
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 149 1e-35
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 148 2e-35
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 148 2e-35
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 148 2e-35
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 148 2e-35
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 148 2e-35
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 148 2e-35
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 148 2e-35
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 148 2e-35
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 148 2e-35
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 148 2e-35
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 148 2e-35
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 148 2e-35
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 146 6e-35
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 143 7e-34
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 143 7e-34
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 143 7e-34
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 142 1e-33
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 142 1e-33
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 142 1e-33
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 142 1e-33
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 142 1e-33
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 142 1e-33
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 141 2e-33
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 139 8e-33
AF542390-1|AAN62841.1| 258|Homo sapiens AT03158-like protein pr... 139 8e-33
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 139 8e-33
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 138 3e-32
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 138 3e-32
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 137 5e-32
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 137 5e-32
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 137 5e-32
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 137 5e-32
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 137 5e-32
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 137 5e-32
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 137 5e-32
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 137 5e-32
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 137 5e-32
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 135 1e-31
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 135 1e-31
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 135 1e-31
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 135 1e-31
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 135 1e-31
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 134 2e-31
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 134 3e-31
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 134 3e-31
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 134 3e-31
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 134 3e-31
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 134 3e-31
AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leuc... 134 3e-31
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 134 3e-31
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 134 4e-31
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 133 6e-31
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 133 7e-31
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 132 1e-30
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 132 1e-30
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 130 4e-30
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 129 9e-30
AB183428-1|BAF73616.1| 580|Homo sapiens maternal embryonic luec... 128 2e-29
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 122 1e-27
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 119 1e-26
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 116 7e-26
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 115 2e-25
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 115 2e-25
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 115 2e-25
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 115 2e-25
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 115 2e-25
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 113 6e-25
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 113 6e-25
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 113 6e-25
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 113 6e-25
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 113 6e-25
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 113 6e-25
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 112 1e-24
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 112 1e-24
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 112 1e-24
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 112 1e-24
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 112 1e-24
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 112 1e-24
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 112 1e-24
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 112 1e-24
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 112 1e-24
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 111 2e-24
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 111 3e-24
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 109 8e-24
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 109 8e-24
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 109 8e-24
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 109 8e-24
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 108 2e-23
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 108 2e-23
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 108 2e-23
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 107 3e-23
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 107 3e-23
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 107 3e-23
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 107 3e-23
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 107 3e-23
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 107 3e-23
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 107 3e-23
AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-depende... 107 4e-23
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 107 6e-23
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 107 6e-23
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 107 6e-23
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 105 1e-22
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 105 1e-22
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 105 1e-22
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 105 1e-22
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 105 1e-22
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 105 1e-22
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 105 1e-22
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 105 1e-22
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 105 1e-22
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 105 1e-22
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 105 1e-22
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 105 1e-22
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 105 1e-22
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 105 1e-22
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 105 1e-22
BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing s... 105 2e-22
BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein. 105 2e-22
AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein. 105 2e-22
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 104 3e-22
BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-depe... 104 3e-22
AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein pr... 104 3e-22
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 104 3e-22
AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-depende... 104 3e-22
AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-depende... 104 3e-22
AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform pr... 104 3e-22
AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-depe... 104 3e-22
AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-depe... 104 3e-22
AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-depende... 104 3e-22
AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-depende... 104 3e-22
AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein. 104 3e-22
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 104 4e-22
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 104 4e-22
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 104 4e-22
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 104 4e-22
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 104 4e-22
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 104 4e-22
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 103 5e-22
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 103 5e-22
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 103 5e-22
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 103 5e-22
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 103 5e-22
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 103 5e-22
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 103 5e-22
U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein ... 103 7e-22
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 103 7e-22
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 103 7e-22
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 103 9e-22
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 103 9e-22
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 103 9e-22
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 103 9e-22
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 102 1e-21
AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting ... 102 1e-21
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 102 1e-21
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 102 2e-21
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 102 2e-21
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 102 2e-21
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 102 2e-21
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 101 2e-21
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 101 2e-21
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 101 2e-21
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 101 2e-21
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 101 3e-21
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 101 3e-21
AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein. 101 3e-21
BC031647-1|AAH31647.1| 520|Homo sapiens calcium/calmodulin-depe... 101 4e-21
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 101 4e-21
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 100 5e-21
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 100 5e-21
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 100 5e-21
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 100 5e-21
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 99 8e-21
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 99 8e-21
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 99 8e-21
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 99 8e-21
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 99 8e-21
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 99 8e-21
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 100 1e-20
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 100 1e-20
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 100 1e-20
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 100 1e-20
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 100 1e-20
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 100 1e-20
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 100 1e-20
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 100 1e-20
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 100 1e-20
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 100 1e-20
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 100 1e-20
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 100 1e-20
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 100 1e-20
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 100 1e-20
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 100 1e-20
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 100 1e-20
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 100 1e-20
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 99 1e-20
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 99 1e-20
AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform pr... 99 2e-20
AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform pr... 99 2e-20
AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform pr... 99 2e-20
AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-depende... 99 2e-20
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 98 3e-20
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 98 3e-20
CR536608-1|CAO03523.1| 326|Homo sapiens pim-3 oncogene protein. 98 3e-20
BX539320-1|CAO03581.1| 326|Homo sapiens pim-3 oncogene protein. 98 3e-20
BC141855-1|AAI41856.1| 326|Homo sapiens pim-3 oncogene protein. 98 3e-20
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 98 3e-20
BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein. 98 3e-20
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 98 3e-20
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 98 3e-20
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 98 3e-20
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 98 3e-20
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 98 3e-20
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 98 3e-20
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 98 3e-20
AB114795-1|BAD42438.1| 326|Homo sapiens serine/threonine kinase... 98 3e-20
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 97 4e-20
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 97 4e-20
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 97 4e-20
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 97 4e-20
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 97 4e-20
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 97 4e-20
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 97 4e-20
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 97 6e-20
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 97 6e-20
L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-depend... 97 6e-20
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 97 6e-20
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 97 6e-20
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 97 6e-20
BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein. 97 6e-20
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 97 6e-20
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 97 6e-20
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 97 6e-20
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 97 6e-20
AL713896-5|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AL713896-3|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AL713896-2|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AL713896-1|CAI13787.1| 453|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AL596247-5|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AL596247-3|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AL596247-2|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AL596247-1|CAI13964.1| 453|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 97 6e-20
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 97 6e-20
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 97 6e-20
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 97 6e-20
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 97 6e-20
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 97 6e-20
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 97 6e-20
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 97 6e-20
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 97 8e-20
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 97 8e-20
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 97 8e-20
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 97 8e-20
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 97 8e-20
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 97 8e-20
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 97 8e-20
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 97 8e-20
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 97 8e-20
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 97 8e-20
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 97 8e-20
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 97 8e-20
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 97 8e-20
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 97 8e-20
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 97 8e-20
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 97 8e-20
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 97 8e-20
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 97 8e-20
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 97 8e-20
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 97 8e-20
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 97 8e-20
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 96 1e-19
D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein. 96 1e-19
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 96 1e-19
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 96 1e-19
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 96 1e-19
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 96 1e-19
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 95 2e-19
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 95 2e-19
U77735-1|AAC78506.1| 334|Homo sapiens pim-2 protooncogene homol... 95 2e-19
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 95 2e-19
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 95 2e-19
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 95 2e-19
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 95 2e-19
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 95 2e-19
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 95 2e-19
BC018111-1|AAH18111.1| 311|Homo sapiens pim-2 oncogene protein. 95 2e-19
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 95 2e-19
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 95 2e-19
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 95 2e-19
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 95 2e-19
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 95 2e-19
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 95 2e-19
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 95 2e-19
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 95 2e-19
AB042425-1|BAA95613.1| 311|Homo sapiens pim-2 protooncogene hom... 95 2e-19
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 95 2e-19
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 95 2e-19
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 95 2e-19
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 95 2e-19
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 95 2e-19
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 95 2e-19
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 95 2e-19
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 95 2e-19
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 95 2e-19
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 95 2e-19
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 95 2e-19
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 95 2e-19
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 95 2e-19
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 95 2e-19
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 95 2e-19
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 95 3e-19
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 95 3e-19
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 94 4e-19
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 94 4e-19
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 94 4e-19
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 94 4e-19
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 94 4e-19
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 94 4e-19
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 94 4e-19
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 94 4e-19
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 94 6e-19
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 94 6e-19
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 94 6e-19
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 93 7e-19
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 93 1e-18
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 93 1e-18
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 93 1e-18
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 93 1e-18
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 93 1e-18
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 93 1e-18
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 93 1e-18
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 93 1e-18
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 93 1e-18
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 93 1e-18
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 93 1e-18
Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma pr... 92 2e-18
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 92 2e-18
BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma... 92 2e-18
AY355461-1|AAQ84219.1| 347|Homo sapiens MNK1-like kinase 1b pro... 92 2e-18
AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma ... 92 2e-18
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 92 2e-18
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 92 2e-18
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 92 2e-18
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 92 2e-18
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 92 2e-18
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 92 2e-18
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 92 2e-18
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 92 2e-18
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 92 2e-18
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 92 2e-18
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 92 2e-18
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 92 2e-18
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 92 2e-18
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 92 2e-18
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 92 2e-18
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 92 2e-18
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 91 3e-18
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 91 3e-18
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 91 3e-18
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 91 3e-18
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 91 3e-18
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 91 3e-18
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 91 3e-18
M14504-1|AAA36519.1| 150|Homo sapiens protein ( Human protein-s... 91 4e-18
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 91 4e-18
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 91 4e-18
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 91 4e-18
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 91 4e-18
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 91 4e-18
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 91 4e-18
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 91 4e-18
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 91 4e-18
AB004885-1|BAA20562.1| 787|Homo sapiens PKU-beta protein. 91 4e-18
U59305-1|AAB37126.1| 496|Homo sapiens ser-thr protein kinase PK... 91 5e-18
DQ355971-1|ABC67469.1| 1711|Homo sapiens CDC42 binding protein k... 91 5e-18
BC048261-1|AAH48261.1| 492|Homo sapiens CDC42BPB protein protein. 91 5e-18
BC047871-1|AAH47871.1| 933|Homo sapiens CDC42BPB protein protein. 91 5e-18
AL627308-5|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 91 5e-18
AL627308-4|CAH71338.1| 1638|Homo sapiens CDC42 binding protein k... 91 5e-18
AL627308-3|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 91 5e-18
AL451047-3|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 91 5e-18
AL451047-2|CAH71184.1| 1638|Homo sapiens CDC42 binding protein k... 91 5e-18
AL451047-1|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 91 5e-18
AL353689-9|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 91 5e-18
AL353689-8|CAI19110.1| 1638|Homo sapiens CDC42 binding protein k... 91 5e-18
AL353689-7|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 91 5e-18
AJ518976-1|CAD57746.1| 1638|Homo sapiens CDC42 binding protein k... 91 5e-18
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 91 5e-18
AF128625-1|AAD37506.1| 1711|Homo sapiens CDC42-binding protein k... 91 5e-18
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 91 5e-18
AB032950-1|BAA86438.2| 1760|Homo sapiens KIAA1124 protein protein. 91 5e-18
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 90 7e-18
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 90 7e-18
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 90 7e-18
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 90 7e-18
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 90 7e-18
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 90 7e-18
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 90 9e-18
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 90 9e-18
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 90 9e-18
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 90 9e-18
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 90 9e-18
AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 90 9e-18
AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 90 9e-18
AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 90 9e-18
AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 90 9e-18
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 90 9e-18
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 89 1e-17
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 89 1e-17
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 89 1e-17
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 89 1e-17
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 89 1e-17
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 89 1e-17
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 89 1e-17
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 89 1e-17
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 89 1e-17
AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase, cAMP-d... 89 1e-17
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 89 1e-17
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 89 1e-17
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 89 1e-17
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 89 1e-17
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 89 1e-17
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 89 1e-17
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 89 1e-17
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 89 1e-17
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 89 2e-17
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 89 2e-17
BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein. 89 2e-17
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 89 2e-17
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 89 2e-17
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 89 2e-17
AB011133-1|BAA25487.1| 1308|Homo sapiens KIAA0561 protein protein. 89 2e-17
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 89 2e-17
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 89 2e-17
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 89 2e-17
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 89 2e-17
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 89 2e-17
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 89 2e-17
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 89 2e-17
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 89 2e-17
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 89 2e-17
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 89 2e-17
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 89 2e-17
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 89 2e-17
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 89 2e-17
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 89 2e-17
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 89 2e-17
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 89 2e-17
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 89 2e-17
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 88 3e-17
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 88 3e-17
S72883-1|AAB31800.1| 625|Homo sapiens myotonin protein kinase p... 88 3e-17
M94203-1|AAA64884.1| 582|Homo sapiens protein kinase protein. 88 3e-17
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 88 3e-17
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 88 3e-17
L19268-1|AAA36206.1| 624|Homo sapiens protein kinase protein. 88 3e-17
>CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein.
Length = 358
Score = 199 bits (485), Expect = 1e-50
Identities = 88/189 (46%), Positives = 132/189 (69%), Gaps = 2/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+YI+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCENLL+D
Sbjct: 86 IYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLD 145
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+GV+
Sbjct: 146 KDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQ 143
LY +V G +P+DD++ ++L+ Q +++V FPR ++ EC+ LI R+L P + R+ I +
Sbjct: 206 LYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDE 265
Query: 142 ILADPWLNP 116
IL+ WL P
Sbjct: 266 ILSHSWLQP 274
>BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 199 bits (485), Expect = 1e-50
Identities = 88/189 (46%), Positives = 132/189 (69%), Gaps = 2/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+YI+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCENLL+D
Sbjct: 86 IYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLD 145
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+GV+
Sbjct: 146 KDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQ 143
LY +V G +P+DD++ ++L+ Q +++V FPR ++ EC+ LI R+L P + R+ I +
Sbjct: 206 LYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDE 265
Query: 142 ILADPWLNP 116
IL+ WL P
Sbjct: 266 ILSHSWLQP 274
>AF362953-1|AAK98531.1| 358|Homo sapiens testis specific
serine/threonine kinase 2 protein.
Length = 358
Score = 199 bits (485), Expect = 1e-50
Identities = 88/189 (46%), Positives = 132/189 (69%), Gaps = 2/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+YI+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCENLL+D
Sbjct: 86 IYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLD 145
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+GV+
Sbjct: 146 KDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQ 143
LY +V G +P+DD++ ++L+ Q +++V FPR ++ EC+ LI R+L P + R+ I +
Sbjct: 206 LYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDE 265
Query: 142 ILADPWLNP 116
IL+ WL P
Sbjct: 266 ILSHSWLQP 274
>AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 199 bits (485), Expect = 1e-50
Identities = 88/189 (46%), Positives = 132/189 (69%), Gaps = 2/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+YI+ME G LL+ I+ + E R+ F+QL AV YCH+ +VHRD+KCENLL+D
Sbjct: 86 IYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLD 145
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIKLSDFGF++ ++ NG LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+GV+
Sbjct: 146 KDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQ 143
LY +V G +P+DD++ ++L+ Q +++V FPR ++ EC+ LI R+L P + R+ I +
Sbjct: 206 LYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDE 265
Query: 142 ILADPWLNP 116
IL+ WL P
Sbjct: 266 ILSHSWLQP 274
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 196 bits (478), Expect = 7e-50
Identities = 89/189 (47%), Positives = 134/189 (70%), Gaps = 2/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VYIVME A G LL++I+ + E R+ F QL A+ YCH+ VVHRD+KC+NLL+D
Sbjct: 86 VYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLD 145
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+ D+WS+GV+
Sbjct: 146 KDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQ 143
LY +V G +P+DD+N ++L+ Q +++V+FPR ++ EC+ LI +L P + R+ I +
Sbjct: 206 LYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDE 265
Query: 142 ILADPWLNP 116
IL+ W+ P
Sbjct: 266 ILSHCWMQP 274
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 196 bits (478), Expect = 7e-50
Identities = 89/189 (47%), Positives = 134/189 (70%), Gaps = 2/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VYIVME A G LL++I+ + E R+ F QL A+ YCH+ VVHRD+KC+NLL+D
Sbjct: 86 VYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLD 145
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+ D+WS+GV+
Sbjct: 146 KDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQ 143
LY +V G +P+DD+N ++L+ Q +++V+FPR ++ EC+ LI +L P + R+ I +
Sbjct: 206 LYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDE 265
Query: 142 ILADPWLNP 116
IL+ W+ P
Sbjct: 266 ILSHCWMQP 274
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 196 bits (478), Expect = 7e-50
Identities = 89/189 (47%), Positives = 134/189 (70%), Gaps = 2/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VYIVME A G LL++I+ + E R+ F QL A+ YCH+ VVHRD+KC+NLL+D
Sbjct: 86 VYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLD 145
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+ D+WS+GV+
Sbjct: 146 KDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQ 143
LY +V G +P+DD+N ++L+ Q +++V+FPR ++ EC+ LI +L P + R+ I +
Sbjct: 206 LYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDE 265
Query: 142 ILADPWLNP 116
IL+ W+ P
Sbjct: 266 ILSHCWMQP 274
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 182 bits (442), Expect = 2e-45
Identities = 88/186 (47%), Positives = 126/186 (67%), Gaps = 1/186 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+ +VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN L+
Sbjct: 84 ICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQ 143
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWSMGVV
Sbjct: 144 -GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVV 199
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQI 140
LY ++ LPFDDT+ ++L Q Q VSFP +SA+C+ L+ R+L P + +R I ++
Sbjct: 200 LYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEV 259
Query: 139 LADPWL 122
PWL
Sbjct: 260 SWHPWL 265
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 182 bits (442), Expect = 2e-45
Identities = 88/186 (47%), Positives = 126/186 (67%), Gaps = 1/186 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+ +VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN L+
Sbjct: 84 ICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQ 143
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWSMGVV
Sbjct: 144 -GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVV 199
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQI 140
LY ++ LPFDDT+ ++L Q Q VSFP +SA+C+ L+ R+L P + +R I ++
Sbjct: 200 LYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEV 259
Query: 139 LADPWL 122
PWL
Sbjct: 260 SWHPWL 265
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 182 bits (442), Expect = 2e-45
Identities = 88/186 (47%), Positives = 126/186 (67%), Gaps = 1/186 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+ +VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN L+
Sbjct: 84 ICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQ 143
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWSMGVV
Sbjct: 144 -GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVV 199
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQI 140
LY ++ LPFDDT+ ++L Q Q VSFP +SA+C+ L+ R+L P + +R I ++
Sbjct: 200 LYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEV 259
Query: 139 LADPWL 122
PWL
Sbjct: 260 SWHPWL 265
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 182 bits (442), Expect = 2e-45
Identities = 88/186 (47%), Positives = 126/186 (67%), Gaps = 1/186 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+ +VME AE G + D + + E+R + F+Q+VEA+ YCH GV HRD+KCEN L+
Sbjct: 84 ICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQ 143
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+PE+L+G+P+ + DVWSMGVV
Sbjct: 144 -GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVV 199
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQI 140
LY ++ LPFDDT+ ++L Q Q VSFP +SA+C+ L+ R+L P + +R I ++
Sbjct: 200 LYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEV 259
Query: 139 LADPWL 122
PWL
Sbjct: 260 SWHPWL 265
>BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein.
Length = 252
Score = 178 bits (433), Expect = 2e-44
Identities = 88/198 (44%), Positives = 123/198 (62%), Gaps = 13/198 (6%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VYI++E A+ G +L+ I++ E +WF QL + Y H + +VHRD+K ENLL+D
Sbjct: 22 VYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLD 81
Query: 496 HGLNIKLSDFGFARGHMKPKN------------GVFA-LSETFCGSYAYASPEILKGVPY 356
N+K+SDFGFA+ M P N F+ LS+T+CGS+AYA PEIL+G+PY
Sbjct: 82 KWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPY 139
Query: 355 RPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
P SD WSMGV+LY +V LPFDDTN +LL++ Q +V+FP +S EC+ LI ++L
Sbjct: 140 NPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQML 199
Query: 175 APLKMRVKIPQILADPWL 122
R I I+ D W+
Sbjct: 200 RQATKRATILDIIKDSWV 217
>AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine
kinase 4 protein.
Length = 328
Score = 178 bits (433), Expect = 2e-44
Identities = 88/198 (44%), Positives = 123/198 (62%), Gaps = 13/198 (6%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VYI++E A+ G +L+ I++ E +WF QL + Y H + +VHRD+K ENLL+D
Sbjct: 98 VYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLD 157
Query: 496 HGLNIKLSDFGFARGHMKPKN------------GVFA-LSETFCGSYAYASPEILKGVPY 356
N+K+SDFGFA+ M P N F+ LS+T+CGS+AYA PEIL+G+PY
Sbjct: 158 KWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPY 215
Query: 355 RPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
P SD WSMGV+LY +V LPFDDTN +LL++ Q +V+FP +S EC+ LI ++L
Sbjct: 216 NPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQML 275
Query: 175 APLKMRVKIPQILADPWL 122
R I I+ D W+
Sbjct: 276 RQATKRATILDIIKDSWV 293
>AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens
cDNA FLJ29008 fis, clone TST06032. ).
Length = 338
Score = 168 bits (408), Expect = 2e-41
Identities = 89/208 (42%), Positives = 123/208 (59%), Gaps = 23/208 (11%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVH----------R 527
VYI++E A+ G +L+ IR+ E +WF QL + Y H + +VH R
Sbjct: 98 VYIILELAQGGDVLEWIRRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRLMPSLSAAGR 157
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKN------------GVFA-LSETFCGSYAYA 386
D+K ENLL+D N+K+SDFGFA+ M P N F+ LS+T+CGS+AYA
Sbjct: 158 DLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYA 215
Query: 385 SPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSA 206
PEIL+G+PY P SD WSMGV+LY +V LPFDDTN +LL++ Q +V+FP +S
Sbjct: 216 CPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQ 275
Query: 205 ECRKLITRILAPLKMRVKIPQILADPWL 122
EC+ LI ++L R I I+ D W+
Sbjct: 276 ECKNLILQMLRQATKRATILDIIKDSWV 303
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 158 bits (383), Expect = 2e-38
Identities = 81/201 (40%), Positives = 118/201 (58%), Gaps = 1/201 (0%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K + I+MEYA G L D I + + + E R +F+Q+V AV YCH+ GVVHRD+K EN+
Sbjct: 162 KDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENI 221
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NIK++DFG + + K K +TFCGS YASPEI+ G PYR + D W++
Sbjct: 222 LLDDNCNIKIADFGLSNLYQKDK-----FLQTFCGSPLYASPEIVNGRPYRGPEVDSWAL 276
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLIT-RILAPLKMRVKI 149
GV+LY +VYG +PFD ++ L++Q+ + REP ++ R LI ++ R I
Sbjct: 277 GVLLYTLVYGTMPFDGFDHKNLIRQISS--GEYREPTQPSDARGLIRWMLMVNPDRRATI 334
Query: 148 PQILADPWLNPNQQSKHDETD 86
I W+N +S + D
Sbjct: 335 EDIANHWWVNWGYKSSVCDCD 355
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 153 bits (371), Expect = 6e-37
Identities = 81/202 (40%), Positives = 123/202 (60%), Gaps = 3/202 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y++MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 128 LYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLD 187
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 188 ADMNIKIADFGFSN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 242
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ R +L P+K R +
Sbjct: 243 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKRFLVLNPIK-RGTLE 299
Query: 145 QILADPWLNPNQQSKHDETDLQ 80
QI+ D W+N + H+E +L+
Sbjct: 300 QIMKDRWIN----AGHEEDELK 317
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 153 bits (371), Expect = 6e-37
Identities = 81/202 (40%), Positives = 123/202 (60%), Gaps = 3/202 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y++MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 128 LYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLD 187
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 188 ADMNIKIADFGFSN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 242
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ R +L P+K R +
Sbjct: 243 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKRFLVLNPIK-RGTLE 299
Query: 145 QILADPWLNPNQQSKHDETDLQ 80
QI+ D W+N + H+E +L+
Sbjct: 300 QIMKDRWIN----AGHEEDELK 317
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 153 bits (371), Expect = 6e-37
Identities = 81/202 (40%), Positives = 123/202 (60%), Gaps = 3/202 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y++MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 128 LYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLD 187
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 188 ADMNIKIADFGFSN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 242
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ R +L P+K R +
Sbjct: 243 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKRFLVLNPIK-RGTLE 299
Query: 145 QILADPWLNPNQQSKHDETDLQ 80
QI+ D W+N + H+E +L+
Sbjct: 300 QIMKDRWIN----AGHEEDELK 317
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 153 bits (371), Expect = 6e-37
Identities = 81/202 (40%), Positives = 123/202 (60%), Gaps = 3/202 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y++MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 128 LYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLD 187
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 188 ADMNIKIADFGFSN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 242
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ R +L P+K R +
Sbjct: 243 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKRFLVLNPIK-RGTLE 299
Query: 145 QILADPWLNPNQQSKHDETDLQ 80
QI+ D W+N + H+E +L+
Sbjct: 300 QIMKDRWIN----AGHEEDELK 317
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 153 bits (371), Expect = 6e-37
Identities = 81/202 (40%), Positives = 123/202 (60%), Gaps = 3/202 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y++MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 128 LYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLD 187
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 188 ADMNIKIADFGFSN-----EFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 242
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ R +L P+K R +
Sbjct: 243 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKRFLVLNPIK-RGTLE 299
Query: 145 QILADPWLNPNQQSKHDETDLQ 80
QI+ D W+N + H+E +L+
Sbjct: 300 QIMKDRWIN----AGHEEDELK 317
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 152 bits (369), Expect = 1e-36
Identities = 81/206 (39%), Positives = 124/206 (60%), Gaps = 3/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 132 LYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLD 191
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 192 GDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 246
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ ++L P+K R +
Sbjct: 247 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RGSLE 303
Query: 145 QILADPWLNPNQQSKHDETDLQEHAK 68
QI+ D W+N H+E +L+ + +
Sbjct: 304 QIMKDRWMNVG----HEEEELKPYTE 325
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 152 bits (369), Expect = 1e-36
Identities = 81/206 (39%), Positives = 124/206 (60%), Gaps = 3/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 132 LYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLD 191
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 192 GDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 246
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ ++L P+K R +
Sbjct: 247 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RGSLE 303
Query: 145 QILADPWLNPNQQSKHDETDLQEHAK 68
QI+ D W+N H+E +L+ + +
Sbjct: 304 QIMKDRWMNVG----HEEEELKPYTE 325
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 152 bits (369), Expect = 1e-36
Identities = 75/186 (40%), Positives = 111/186 (59%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+ IVMEYA G L D I + Q + E R +F+Q+V AV YCH+ VVHRD+K EN+L+D
Sbjct: 125 IVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLD 184
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIK++DFG + + + K +TFCGS YASPEI+ G PY + D WS+GV+
Sbjct: 185 ANGNIKIADFGLSNLYHQGK-----FLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVL 239
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPLKMRVKIPQIL 137
LY +V+G +PFD ++ L+KQ+ N ++ PK S C + ++ R + +
Sbjct: 240 LYILVHGTMPFDGHDHKILVKQISNG-AYREPPKPSDACGLIRWLLMVNPTRRATLEDVA 298
Query: 136 ADPWLN 119
+ W+N
Sbjct: 299 SHWWVN 304
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 152 bits (369), Expect = 1e-36
Identities = 81/206 (39%), Positives = 124/206 (60%), Gaps = 3/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 132 LYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLD 191
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 192 GDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 246
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ ++L P+K R +
Sbjct: 247 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RGSLE 303
Query: 145 QILADPWLNPNQQSKHDETDLQEHAK 68
QI+ D W+N H+E +L+ + +
Sbjct: 304 QIMKDRWMNVG----HEEEELKPYTE 325
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 152 bits (369), Expect = 1e-36
Identities = 75/186 (40%), Positives = 111/186 (59%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+ IVMEYA G L D I + Q + E R +F+Q+V AV YCH+ VVHRD+K EN+L+D
Sbjct: 125 IVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLD 184
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIK++DFG + + + K +TFCGS YASPEI+ G PY + D WS+GV+
Sbjct: 185 ANGNIKIADFGLSNLYHQGK-----FLQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVL 239
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPLKMRVKIPQIL 137
LY +V+G +PFD ++ L+KQ+ N ++ PK S C + ++ R + +
Sbjct: 240 LYILVHGTMPFDGHDHKILVKQISNG-AYREPPKPSDACGLIRWLLMVNPTRRATLEDVA 298
Query: 136 ADPWLN 119
+ W+N
Sbjct: 299 SHWWVN 304
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 152 bits (369), Expect = 1e-36
Identities = 81/206 (39%), Positives = 124/206 (60%), Gaps = 3/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 132 LYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLD 191
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 192 GDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 246
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ ++L P+K R +
Sbjct: 247 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RGSLE 303
Query: 145 QILADPWLNPNQQSKHDETDLQEHAK 68
QI+ D W+N H+E +L+ + +
Sbjct: 304 QIMKDRWMNVG----HEEEELKPYTE 325
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 151 bits (367), Expect = 2e-36
Identities = 82/190 (43%), Positives = 115/190 (60%), Gaps = 2/190 (1%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K ++Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENL
Sbjct: 89 KSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENL 148
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y D+WSM
Sbjct: 149 LLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSM 203
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--ILAPLKMRVK 152
GVVLY +V G LPFD +L+Q + F +S +C LI R +L P K R+
Sbjct: 204 GVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK-RLT 261
Query: 151 IPQILADPWL 122
I QI W+
Sbjct: 262 IAQIKEHKWM 271
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 151 bits (367), Expect = 2e-36
Identities = 82/190 (43%), Positives = 115/190 (60%), Gaps = 2/190 (1%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K ++Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENL
Sbjct: 89 KSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENL 148
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y D+WSM
Sbjct: 149 LLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSM 203
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--ILAPLKMRVK 152
GVVLY +V G LPFD +L+Q + F +S +C LI R +L P K R+
Sbjct: 204 GVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK-RLT 261
Query: 151 IPQILADPWL 122
I QI W+
Sbjct: 262 IAQIKEHKWM 271
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 151 bits (367), Expect = 2e-36
Identities = 82/190 (43%), Positives = 115/190 (60%), Gaps = 2/190 (1%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K ++Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENL
Sbjct: 87 KSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENL 146
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y D+WSM
Sbjct: 147 LLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSM 201
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--ILAPLKMRVK 152
GVVLY +V G LPFD +L+Q + F +S +C LI R +L P K R+
Sbjct: 202 GVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK-RLT 259
Query: 151 IPQILADPWL 122
I QI W+
Sbjct: 260 IAQIKEHKWM 269
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 151 bits (367), Expect = 2e-36
Identities = 82/190 (43%), Positives = 115/190 (60%), Gaps = 2/190 (1%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K ++Y+V EYA+NG + D + ++E+ RR F Q++ AVDYCH R +VHRD+K ENL
Sbjct: 113 KSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENL 172
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y D+WSM
Sbjct: 173 LLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSM 227
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--ILAPLKMRVK 152
GVVLY +V G LPFD +L+Q + F +S +C LI R +L P K R+
Sbjct: 228 GVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSK-RLT 285
Query: 151 IPQILADPWL 122
I QI W+
Sbjct: 286 IAQIKEHKWM 295
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 149 bits (361), Expect = 1e-35
Identities = 80/191 (41%), Positives = 118/191 (61%), Gaps = 3/191 (1%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K ++YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENL
Sbjct: 96 KDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENL 155
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D ++IKL+DFGF + K+G LS T+CGS YA+PE+ +G Y D+WS+
Sbjct: 156 LLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSL 210
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 155
GVVLY +V G LPFD N L ++V + + P +S +C LI R+L P + R+
Sbjct: 211 GVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIRRMLVVDPAR-RI 267
Query: 154 KIPQILADPWL 122
I QI W+
Sbjct: 268 TIAQIRQHRWM 278
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 149 bits (361), Expect = 1e-35
Identities = 80/191 (41%), Positives = 118/191 (61%), Gaps = 3/191 (1%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K ++YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENL
Sbjct: 77 KDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENL 136
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D ++IKL+DFGF + K+G LS T+CGS YA+PE+ +G Y D+WS+
Sbjct: 137 LLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSL 191
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 155
GVVLY +V G LPFD N L ++V + + P +S +C LI R+L P + R+
Sbjct: 192 GVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIRRMLVVDPAR-RI 248
Query: 154 KIPQILADPWL 122
I QI W+
Sbjct: 249 TIAQIRQHRWM 259
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 149 bits (361), Expect = 1e-35
Identities = 80/191 (41%), Positives = 118/191 (61%), Gaps = 3/191 (1%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K ++YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENL
Sbjct: 96 KDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENL 155
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D ++IKL+DFGF + K+G LS T+CGS YA+PE+ +G Y D+WS+
Sbjct: 156 LLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDIWSL 210
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRV 155
GVVLY +V G LPFD N L ++V + + P +S +C LI R+L P + R+
Sbjct: 211 GVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIRRMLVVDPAR-RI 267
Query: 154 KIPQILADPWL 122
I QI W+
Sbjct: 268 TIAQIRQHRWM 278
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 148 bits (359), Expect = 2e-35
Identities = 80/206 (38%), Positives = 121/206 (58%), Gaps = 3/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 92 LYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLD 151
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 152 ADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 206
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R +
Sbjct: 207 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RGTLE 263
Query: 145 QILADPWLNPNQQSKHDETDLQEHAK 68
QI+ D W+N H++ +L+ + +
Sbjct: 264 QIMKDRWMNVG----HEDDELKPYVE 285
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 148 bits (359), Expect = 2e-35
Identities = 80/206 (38%), Positives = 121/206 (58%), Gaps = 3/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 92 LYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLD 151
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 152 ADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 206
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R +
Sbjct: 207 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RGTLE 263
Query: 145 QILADPWLNPNQQSKHDETDLQEHAK 68
QI+ D W+N H++ +L+ + +
Sbjct: 264 QIMKDRWMNVG----HEDDELKPYVE 285
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 148 bits (359), Expect = 2e-35
Identities = 80/206 (38%), Positives = 121/206 (58%), Gaps = 3/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 125 LYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLD 184
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 185 ADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 239
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R +
Sbjct: 240 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RGTLE 296
Query: 145 QILADPWLNPNQQSKHDETDLQEHAK 68
QI+ D W+N H++ +L+ + +
Sbjct: 297 QIMKDRWMNVG----HEDDELKPYVE 318
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 148 bits (359), Expect = 2e-35
Identities = 80/206 (38%), Positives = 121/206 (58%), Gaps = 3/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 115 LYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLD 174
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 175 ADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 229
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R +
Sbjct: 230 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RGTLE 286
Query: 145 QILADPWLNPNQQSKHDETDLQEHAK 68
QI+ D W+N H++ +L+ + +
Sbjct: 287 QIMKDRWMNVG----HEDDELKPYVE 308
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 148 bits (359), Expect = 2e-35
Identities = 80/206 (38%), Positives = 121/206 (58%), Gaps = 3/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 92 LYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLD 151
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 152 ADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 206
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R +
Sbjct: 207 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RGTLE 263
Query: 145 QILADPWLNPNQQSKHDETDLQEHAK 68
QI+ D W+N H++ +L+ + +
Sbjct: 264 QIMKDRWMNVG----HEDDELKPYVE 285
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 148 bits (359), Expect = 2e-35
Identities = 80/206 (38%), Positives = 121/206 (58%), Gaps = 3/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 125 LYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLD 184
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+NIK++DFGF+ +TFCGS YA+PE+ +G Y + DVWS+GV+
Sbjct: 185 ADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVI 239
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C L+ + IL P K R +
Sbjct: 240 LYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFLILNPSK-RGTLE 296
Query: 145 QILADPWLNPNQQSKHDETDLQEHAK 68
QI+ D W+N H++ +L+ + +
Sbjct: 297 QIMKDRWMNVG----HEDDELKPYVE 318
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 148 bits (358), Expect = 2e-35
Identities = 76/189 (40%), Positives = 115/189 (60%), Gaps = 3/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 131 LYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD 190
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+
Sbjct: 191 AEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVI 245
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R +
Sbjct: 246 LYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLE 302
Query: 145 QILADPWLN 119
QI+ D W+N
Sbjct: 303 QIMKDKWIN 311
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 148 bits (358), Expect = 2e-35
Identities = 76/189 (40%), Positives = 115/189 (60%), Gaps = 3/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 131 LYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD 190
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+
Sbjct: 191 AEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVI 245
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R +
Sbjct: 246 LYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLE 302
Query: 145 QILADPWLN 119
QI+ D W+N
Sbjct: 303 QIMKDKWIN 311
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 148 bits (358), Expect = 2e-35
Identities = 76/189 (40%), Positives = 115/189 (60%), Gaps = 3/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 131 LYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD 190
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+
Sbjct: 191 AEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVI 245
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R +
Sbjct: 246 LYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLE 302
Query: 145 QILADPWLN 119
QI+ D W+N
Sbjct: 303 QIMKDKWIN 311
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 148 bits (358), Expect = 2e-35
Identities = 76/189 (40%), Positives = 115/189 (60%), Gaps = 3/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 131 LYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD 190
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+
Sbjct: 191 AEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVI 245
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R +
Sbjct: 246 LYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLE 302
Query: 145 QILADPWLN 119
QI+ D W+N
Sbjct: 303 QIMKDKWIN 311
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 148 bits (358), Expect = 2e-35
Identities = 76/189 (40%), Positives = 115/189 (60%), Gaps = 3/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 132 LYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD 191
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+
Sbjct: 192 AEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVI 246
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R +
Sbjct: 247 LYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLE 303
Query: 145 QILADPWLN 119
QI+ D W+N
Sbjct: 304 QIMKDKWIN 312
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 148 bits (358), Expect = 2e-35
Identities = 76/189 (40%), Positives = 115/189 (60%), Gaps = 3/189 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+VMEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D
Sbjct: 131 LYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLD 190
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+
Sbjct: 191 AEANIKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVI 245
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIP 146
LY +V G LPFD N +L ++V + K P +S +C ++ R +L P K R +
Sbjct: 246 LYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLE 302
Query: 145 QILADPWLN 119
QI+ D W+N
Sbjct: 303 QIMKDKWIN 311
>AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens
cDNA FLJ14587 fis, clone NT2RM4001758, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK
(EC 2.7.1.-). ).
Length = 638
Score = 147 bits (355), Expect = 6e-35
Identities = 79/202 (39%), Positives = 120/202 (59%), Gaps = 3/202 (1%)
Frame = -2
Query: 664 MEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLN 485
MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +N
Sbjct: 1 MEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMN 60
Query: 484 IKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAI 305
IK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+LY +
Sbjct: 61 IKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTL 115
Query: 304 VYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQILA 134
V G LPFD N +L ++V + K P +S +C L+ ++L P+K R + QI+
Sbjct: 116 VSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RGSLEQIMK 172
Query: 133 DPWLNPNQQSKHDETDLQEHAK 68
D W+N H+E +L+ + +
Sbjct: 173 DRWMNVG----HEEEELKPYTE 190
>BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine
kinase 6 protein.
Length = 273
Score = 143 bits (346), Expect = 7e-34
Identities = 78/187 (41%), Positives = 111/187 (59%), Gaps = 2/187 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+YIVME A LL ++++ I + R F Q+ AV Y H+ +VHRD+KCEN+L+
Sbjct: 86 LYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLS 144
Query: 496 HG-LNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 320
+KL+DFGF R +G LS T+CGS AYASPE+L G+PY P+ DVWSMGV
Sbjct: 145 PDERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGV 200
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQ 143
VLY +V G +PFDD++ L ++ + V +P ++S C+ LI +L R Q
Sbjct: 201 VLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQ 260
Query: 142 ILADPWL 122
+ + WL
Sbjct: 261 VARNCWL 267
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 143 bits (346), Expect = 7e-34
Identities = 80/194 (41%), Positives = 118/194 (60%), Gaps = 6/194 (3%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K ++YIV E+A+NG + D + + H+ E R+ F Q++ AV+YCH+ +VHRD+K ENL
Sbjct: 96 KDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENL 155
Query: 505 LMDHGLNIKLS---DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 335
L+D ++IKL+ DFGF + K+G LS T+CGS YA+PE+ +G Y D+
Sbjct: 156 LLDGNMDIKLAGTEDFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYEGPQLDI 210
Query: 334 WSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLK 164
WS+GVVLY +V G LPFD N L ++V + + P +S +C LI R+L P +
Sbjct: 211 WSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIRRMLVVDPAR 268
Query: 163 MRVKIPQILADPWL 122
R+ I QI W+
Sbjct: 269 -RITIAQIRQHRWM 281
>AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protein
kinase SSTK protein.
Length = 273
Score = 143 bits (346), Expect = 7e-34
Identities = 78/187 (41%), Positives = 111/187 (59%), Gaps = 2/187 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+YIVME A LL ++++ I + R F Q+ AV Y H+ +VHRD+KCEN+L+
Sbjct: 86 LYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLS 144
Query: 496 HG-LNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 320
+KL+DFGF R +G LS T+CGS AYASPE+L G+PY P+ DVWSMGV
Sbjct: 145 PDERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGV 200
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQ 143
VLY +V G +PFDD++ L ++ + V +P ++S C+ LI +L R Q
Sbjct: 201 VLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQ 260
Query: 142 ILADPWL 122
+ + WL
Sbjct: 261 VARNCWL 267
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 142 bits (344), Expect = 1e-33
Identities = 71/188 (37%), Positives = 112/188 (59%), Gaps = 1/188 (0%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q+V A+D+CH + HRD+K ENL
Sbjct: 103 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENL 162
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE++KG Y + +D+WS
Sbjct: 163 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSC 217
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 149
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+ ++ + R+ +
Sbjct: 218 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSL 276
Query: 148 PQILADPW 125
QI PW
Sbjct: 277 EQIQKHPW 284
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 142 bits (344), Expect = 1e-33
Identities = 71/188 (37%), Positives = 112/188 (59%), Gaps = 1/188 (0%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q+V A+D+CH + HRD+K ENL
Sbjct: 103 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENL 162
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE++KG Y + +D+WS
Sbjct: 163 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSC 217
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 149
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+ ++ + R+ +
Sbjct: 218 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSL 276
Query: 148 PQILADPW 125
QI PW
Sbjct: 277 EQIQKHPW 284
>AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens
cDNA FLJ90097 fis, clone HEMBA1005929, weakly similar to
H.sapiens mRNA for serine/threonine protein kinase EMK.
).
Length = 426
Score = 142 bits (344), Expect = 1e-33
Identities = 74/185 (40%), Positives = 111/185 (60%), Gaps = 3/185 (1%)
Frame = -2
Query: 664 MEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLN 485
MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D N
Sbjct: 1 MEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEAN 60
Query: 484 IKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAI 305
IK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+LY +
Sbjct: 61 IKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTL 115
Query: 304 VYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIPQILA 134
V G LPFD N +L ++V + K P +S +C ++ R +L P K R + QI+
Sbjct: 116 VSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLEQIMK 172
Query: 133 DPWLN 119
D W+N
Sbjct: 173 DKWIN 177
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 142 bits (344), Expect = 1e-33
Identities = 71/188 (37%), Positives = 112/188 (59%), Gaps = 1/188 (0%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q+V A+D+CH + HRD+K ENL
Sbjct: 103 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENL 162
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE++KG Y + +D+WS
Sbjct: 163 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSC 217
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 149
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+ ++ + R+ +
Sbjct: 218 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSL 276
Query: 148 PQILADPW 125
QI PW
Sbjct: 277 EQIQKHPW 284
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 142 bits (344), Expect = 1e-33
Identities = 71/188 (37%), Positives = 112/188 (59%), Gaps = 1/188 (0%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q+V A+D+CH + HRD+K ENL
Sbjct: 119 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENL 178
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE++KG Y + +D+WS
Sbjct: 179 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSC 233
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 149
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+ ++ + R+ +
Sbjct: 234 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSL 292
Query: 148 PQILADPW 125
QI PW
Sbjct: 293 EQIQKHPW 300
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 142 bits (344), Expect = 1e-33
Identities = 71/188 (37%), Positives = 112/188 (59%), Gaps = 1/188 (0%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q+V A+D+CH + HRD+K ENL
Sbjct: 40 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENL 99
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE++KG Y + +D+WS
Sbjct: 100 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIKGEKYDGRRADMWSC 154
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 149
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+ ++ + R+ +
Sbjct: 155 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLLRGMIEVEPEKRLSL 213
Query: 148 PQILADPW 125
QI PW
Sbjct: 214 EQIQKHPW 221
>AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens
cDNA FLJ24002 fis, clone KAIA4350, highly similar to
Homo sapiens serine/threonine protein kinase SSTK
(SSTK). ).
Length = 406
Score = 141 bits (342), Expect = 2e-33
Identities = 76/180 (42%), Positives = 110/180 (61%), Gaps = 3/180 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+YIVME A LL ++++ I + R F Q+ AV Y H+ +VHRD+KCEN+L+
Sbjct: 86 LYIVMEAAAT-DLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLS 144
Query: 496 HG-LNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 320
+KL+DFGF R +G LS T+CGS AYASPE+L G+PY P+ DVWSMGV
Sbjct: 145 PDERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGV 200
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVKIP 146
VLY +V G +PFDD++ L ++ + V +P ++S C+ LI A P++ ++ P
Sbjct: 201 VLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAEAAAVQPVRQALRGP 260
>AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 758
Score = 139 bits (337), Expect = 8e-33
Identities = 75/203 (36%), Positives = 119/203 (58%), Gaps = 3/203 (1%)
Frame = -2
Query: 667 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 488
++ + G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +
Sbjct: 113 ILNHPNIGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDM 172
Query: 487 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYA 308
NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+LY
Sbjct: 173 NIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYT 227
Query: 307 IVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQIL 137
+V G LPFD N +L ++V + K P +S +C L+ ++L P+K R + QI+
Sbjct: 228 LVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RGSLEQIM 284
Query: 136 ADPWLNPNQQSKHDETDLQEHAK 68
D W+N H+E +L+ + +
Sbjct: 285 KDRWMNVG----HEEEELKPYTE 303
>AF542390-1|AAN62841.1| 258|Homo sapiens AT03158-like protein
protein.
Length = 258
Score = 139 bits (337), Expect = 8e-33
Identities = 71/149 (47%), Positives = 95/149 (63%), Gaps = 13/149 (8%)
Frame = -2
Query: 529 RDIKCENLLMDHGLNIKLSDFGFARGHMKPKN------------GVFA-LSETFCGSYAY 389
RD+K ENLL+D N+K+SDFGFA+ M P N F+ LS+T+CGS+AY
Sbjct: 77 RDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAY 134
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 209
A PEIL+G+PY P SD WSMGV+LY +V LPFDDTN +LL++ Q +V+FP +S
Sbjct: 135 ACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTIS 194
Query: 208 AECRKLITRILAPLKMRVKIPQILADPWL 122
EC+ LI ++L R I I+ D W+
Sbjct: 195 QECKNLILQMLRQATKRATILDIIKDSWV 223
>AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein.
Length = 870
Score = 139 bits (337), Expect = 8e-33
Identities = 75/203 (36%), Positives = 119/203 (58%), Gaps = 3/203 (1%)
Frame = -2
Query: 667 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 488
++ + G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +
Sbjct: 225 ILNHPNIGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDM 284
Query: 487 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYA 308
NIK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+LY
Sbjct: 285 NIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYT 339
Query: 307 IVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQIL 137
+V G LPFD N +L ++V + K P +S +C L+ ++L P+K R + QI+
Sbjct: 340 LVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RGSLEQIM 396
Query: 136 ADPWLNPNQQSKHDETDLQEHAK 68
D W+N H+E +L+ + +
Sbjct: 397 KDRWMNVG----HEEEELKPYTE 415
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 138 bits (333), Expect = 3e-32
Identities = 78/189 (41%), Positives = 108/189 (57%), Gaps = 3/189 (1%)
Frame = -2
Query: 679 LVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
++Y+V EYA G + D + + E RR FKQ+V AV +CH R +VHRD+K ENLL+
Sbjct: 79 MIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLL 138
Query: 499 DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 320
D LNIK++DFGF+ + L +T+CGS YA+PE+ +G Y D+WS+GV
Sbjct: 139 DANLNIKIADFGFSNLFTPGQ-----LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGV 193
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKI 149
VLY +V G LPFD + L +V K P +S EC LI +L P K R+ +
Sbjct: 194 VLYVLVCGALPFDGSTLQNLRARVLSGKFRIPF--FMSTECEHLIRHMLVLDPNK-RLSM 250
Query: 148 PQILADPWL 122
QI W+
Sbjct: 251 EQICKHKWM 259
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 138 bits (333), Expect = 3e-32
Identities = 78/189 (41%), Positives = 108/189 (57%), Gaps = 3/189 (1%)
Frame = -2
Query: 679 LVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
++Y+V EYA G + D + + E RR FKQ+V AV +CH R +VHRD+K ENLL+
Sbjct: 187 MIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLL 246
Query: 499 DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 320
D LNIK++DFGF+ + L +T+CGS YA+PE+ +G Y D+WS+GV
Sbjct: 247 DANLNIKIADFGFSNLFTPGQ-----LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGV 301
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKI 149
VLY +V G LPFD + L +V K P +S EC LI +L P K R+ +
Sbjct: 302 VLYVLVCGALPFDGSTLQNLRARVLSGKFRIPF--FMSTECEHLIRHMLVLDPNK-RLSM 358
Query: 148 PQILADPWL 122
QI W+
Sbjct: 359 EQICKHKWM 367
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 137 bits (331), Expect = 5e-32
Identities = 65/166 (39%), Positives = 102/166 (61%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q++ A+D+CH + HRD+K ENL
Sbjct: 88 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 147
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE+++G Y + +DVWS
Sbjct: 148 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSC 202
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 188
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+
Sbjct: 203 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 137 bits (331), Expect = 5e-32
Identities = 65/166 (39%), Positives = 102/166 (61%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q++ A+D+CH + HRD+K ENL
Sbjct: 88 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 147
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE+++G Y + +DVWS
Sbjct: 148 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSC 202
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 188
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+
Sbjct: 203 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 137 bits (331), Expect = 5e-32
Identities = 65/166 (39%), Positives = 102/166 (61%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q++ A+D+CH + HRD+K ENL
Sbjct: 134 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 193
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE+++G Y + +DVWS
Sbjct: 194 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSC 248
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 188
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+
Sbjct: 249 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 293
>AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 603
Score = 137 bits (331), Expect = 5e-32
Identities = 65/166 (39%), Positives = 102/166 (61%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q++ A+D+CH + HRD+K ENL
Sbjct: 17 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 76
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE+++G Y + +DVWS
Sbjct: 77 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSC 131
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 188
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+
Sbjct: 132 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 176
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 137 bits (331), Expect = 5e-32
Identities = 65/166 (39%), Positives = 102/166 (61%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q++ A+D+CH + HRD+K ENL
Sbjct: 88 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 147
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE+++G Y + +DVWS
Sbjct: 148 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSC 202
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 188
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+
Sbjct: 203 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 137 bits (331), Expect = 5e-32
Identities = 65/166 (39%), Positives = 102/166 (61%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q++ A+D+CH + HRD+K ENL
Sbjct: 88 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 147
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE+++G Y + +DVWS
Sbjct: 148 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSC 202
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 188
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+
Sbjct: 203 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 137 bits (331), Expect = 5e-32
Identities = 65/166 (39%), Positives = 102/166 (61%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q++ A+D+CH + HRD+K ENL
Sbjct: 88 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 147
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE+++G Y + +DVWS
Sbjct: 148 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSC 202
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 188
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+
Sbjct: 203 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 137 bits (331), Expect = 5e-32
Identities = 65/166 (39%), Positives = 102/166 (61%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q++ A+D+CH + HRD+K ENL
Sbjct: 88 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 147
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE+++G Y + +DVWS
Sbjct: 148 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSC 202
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 188
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+
Sbjct: 203 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 137 bits (331), Expect = 5e-32
Identities = 65/166 (39%), Positives = 102/166 (61%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K +Y+V+E+ G L D + K + R++F+Q++ A+D+CH + HRD+K ENL
Sbjct: 88 KKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENL 147
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D NI+++DFG A + +L ET CGS YA PE+++G Y + +DVWS
Sbjct: 148 LLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVIRGEKYDGRKADVWSC 202
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLI 188
GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L+
Sbjct: 203 GVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSLL 247
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 135 bits (327), Expect = 1e-31
Identities = 75/192 (39%), Positives = 108/192 (56%), Gaps = 2/192 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D
Sbjct: 90 FMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDA 149
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
+N K++DFG + +G F T CGS YA+PE++ G Y + D+WS GV+L
Sbjct: 150 HMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVIL 204
Query: 313 YAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQI 140
YA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R I I
Sbjct: 205 YALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RATIKDI 262
Query: 139 LADPWLNPNQQS 104
W + S
Sbjct: 263 REHEWFKQDLPS 274
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 135 bits (327), Expect = 1e-31
Identities = 75/192 (39%), Positives = 108/192 (56%), Gaps = 2/192 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D
Sbjct: 90 FMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDA 149
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
+N K++DFG + +G F T CGS YA+PE++ G Y + D+WS GV+L
Sbjct: 150 HMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVIL 204
Query: 313 YAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQI 140
YA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R I I
Sbjct: 205 YALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RATIKDI 262
Query: 139 LADPWLNPNQQS 104
W + S
Sbjct: 263 REHEWFKQDLPS 274
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 135 bits (327), Expect = 1e-31
Identities = 75/192 (39%), Positives = 108/192 (56%), Gaps = 2/192 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D
Sbjct: 90 FMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDA 149
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
+N K++DFG + +G F T CGS YA+PE++ G Y + D+WS GV+L
Sbjct: 150 HMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVIL 204
Query: 313 YAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQI 140
YA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R I I
Sbjct: 205 YALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RATIKDI 262
Query: 139 LADPWLNPNQQS 104
W + S
Sbjct: 263 REHEWFKQDLPS 274
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 135 bits (327), Expect = 1e-31
Identities = 75/192 (39%), Positives = 108/192 (56%), Gaps = 2/192 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D
Sbjct: 90 FMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDA 149
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
+N K++DFG + +G F T CGS YA+PE++ G Y + D+WS GV+L
Sbjct: 150 HMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVIL 204
Query: 313 YAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQI 140
YA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R I I
Sbjct: 205 YALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RATIKDI 262
Query: 139 LADPWLNPNQQS 104
W + S
Sbjct: 263 REHEWFKQDLPS 274
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 135 bits (327), Expect = 1e-31
Identities = 75/192 (39%), Positives = 108/192 (56%), Gaps = 2/192 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D
Sbjct: 90 FMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDA 149
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
+N K++DFG + +G F T CGS YA+PE++ G Y + D+WS GV+L
Sbjct: 150 HMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVIL 204
Query: 313 YAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQI 140
YA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R I I
Sbjct: 205 YALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RATIKDI 262
Query: 139 LADPWLNPNQQS 104
W + S
Sbjct: 263 REHEWFKQDLPS 274
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 134 bits (325), Expect = 2e-31
Identities = 70/179 (39%), Positives = 107/179 (59%), Gaps = 3/179 (1%)
Frame = -2
Query: 646 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 467
G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D NIK++DF
Sbjct: 171 GEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADF 230
Query: 466 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 287
GF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+LY +V G LP
Sbjct: 231 GFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLP 285
Query: 286 FDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIPQILADPWLN 119
FD N +L ++V + K P +S +C ++ R +L P K R + QI+ D W+N
Sbjct: 286 FDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLEQIMKDKWIN 341
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 134 bits (324), Expect = 3e-31
Identities = 72/187 (38%), Positives = 105/187 (56%), Gaps = 2/187 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+++V+EY G L D I + E R F+Q+V AV Y H +G HRD+K ENLL D
Sbjct: 87 IFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFD 146
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG++
Sbjct: 147 EYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGIL 203
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQ 143
LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R+ +
Sbjct: 204 LYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISMKN 261
Query: 142 ILADPWL 122
+L PW+
Sbjct: 262 LLNHPWI 268
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 134 bits (324), Expect = 3e-31
Identities = 72/187 (38%), Positives = 105/187 (56%), Gaps = 2/187 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+++V+EY G L D I + E R F+Q+V AV Y H +G HRD+K ENLL D
Sbjct: 82 IFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFD 141
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG++
Sbjct: 142 EYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGIL 198
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQ 143
LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R+ +
Sbjct: 199 LYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISMKN 256
Query: 142 ILADPWL 122
+L PW+
Sbjct: 257 LLNHPWI 263
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 134 bits (324), Expect = 3e-31
Identities = 72/187 (38%), Positives = 105/187 (56%), Gaps = 2/187 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+++V+EY G L D I + E R F+Q+V AV Y H +G HRD+K ENLL D
Sbjct: 82 IFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFD 141
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG++
Sbjct: 142 EYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGIL 198
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQ 143
LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R+ +
Sbjct: 199 LYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISMKN 256
Query: 142 ILADPWL 122
+L PW+
Sbjct: 257 LLNHPWI 263
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 134 bits (324), Expect = 3e-31
Identities = 72/187 (38%), Positives = 105/187 (56%), Gaps = 2/187 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+++V+EY G L D I + E R F+Q+V AV Y H +G HRD+K ENLL D
Sbjct: 82 IFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFD 141
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG++
Sbjct: 142 EYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGIL 198
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQ 143
LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R+ +
Sbjct: 199 LYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISMKN 256
Query: 142 ILADPWL 122
+L PW+
Sbjct: 257 LLNHPWI 263
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 134 bits (324), Expect = 3e-31
Identities = 72/187 (38%), Positives = 105/187 (56%), Gaps = 2/187 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+++V+EY G L D I + E R F+Q+V AV Y H +G HRD+K ENLL D
Sbjct: 82 IFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFD 141
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG++
Sbjct: 142 EYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGIL 198
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQ 143
LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R+ +
Sbjct: 199 LYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISMKN 256
Query: 142 ILADPWL 122
+L PW+
Sbjct: 257 LLNHPWI 263
>AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leucine
zipper kinase v2 protein.
Length = 619
Score = 134 bits (324), Expect = 3e-31
Identities = 72/187 (38%), Positives = 105/187 (56%), Gaps = 2/187 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+++V+EY G L D I + E R F+Q+V AV Y H +G HRD+K ENLL D
Sbjct: 50 IFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFD 109
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG++
Sbjct: 110 EYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGIL 166
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQ 143
LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R+ +
Sbjct: 167 LYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISMKN 224
Query: 142 ILADPWL 122
+L PW+
Sbjct: 225 LLNHPWI 231
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 134 bits (324), Expect = 3e-31
Identities = 72/187 (38%), Positives = 109/187 (58%), Gaps = 3/187 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+++VMEY G L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN+L+D
Sbjct: 91 IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD 150
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+N K++DFG + +G F T CGS YA+PE++ G Y + D+WS GV+
Sbjct: 151 AHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSF-PR--EPKVSAECRKLITRILAPLKMRVKIP 146
LYA++ G LPFDD + L K++ + + + P+ P V + + ++ + P+K R I
Sbjct: 206 LYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQ--VDPMK-RASIK 262
Query: 145 QILADPW 125
I W
Sbjct: 263 DIREHEW 269
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 134 bits (323), Expect = 4e-31
Identities = 63/143 (44%), Positives = 90/143 (62%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+++VMEY G L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN+L+D
Sbjct: 91 IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD 150
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+N K++DFG + +G F T CGS YA+PE++ G Y + D+WS GV+
Sbjct: 151 AHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV 248
LYA++ G LPFDD + L K++
Sbjct: 206 LYALLCGTLPFDDDHVPTLFKKI 228
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 133 bits (322), Expect = 6e-31
Identities = 73/185 (39%), Positives = 105/185 (56%), Gaps = 2/185 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
++VMEY G L D I K ++E RR F+Q++ AVDYCH VVHRD+K EN+L+D
Sbjct: 90 FMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDA 149
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
+N K++DFG + +G F T CGS Y +PE++ G Y + D+WS GV+L
Sbjct: 150 HMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYTAPEVISGRLYAGPEVDIWSCGVIL 204
Query: 313 YAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQI 140
YA++ G LPFDD + L K+++ V + E ++ L+ +L PLK R I I
Sbjct: 205 YALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQVDPLK-RATIKDI 262
Query: 139 LADPW 125
W
Sbjct: 263 REHEW 267
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 133 bits (321), Expect = 7e-31
Identities = 79/220 (35%), Positives = 127/220 (57%), Gaps = 8/220 (3%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
+Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN++
Sbjct: 89 LYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVF 148
Query: 499 --DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
GL +KL+DFGF+ K T CGS AY++PEIL G Y D+WS+
Sbjct: 149 FEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIWSL 202
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKVSAECRKLITRIL-APLKMRVK 152
GV+L+ +V G+ PF + N ++ L + + K + P VS EC+ LITR+L K R
Sbjct: 203 GVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH--VSKECKDLITRMLQRDPKRRAS 260
Query: 151 IPQILADPWL---NPNQQSKHDETDLQEHAKTSKEEIKSV 41
+ +I PWL +P+ +K++ L + S+EE S+
Sbjct: 261 LEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSEEEHNSI 299
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 132 bits (319), Expect = 1e-30
Identities = 79/220 (35%), Positives = 127/220 (57%), Gaps = 8/220 (3%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
+Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN++
Sbjct: 88 LYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVF 147
Query: 499 --DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
GL +KL+DFGF+ K T CGS AY++PEIL G Y D+WS+
Sbjct: 148 FEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIWSL 201
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKVSAECRKLITRIL-APLKMRVK 152
GV+L+ +V G+ PF + N ++ L + + K + P VS EC+ LITR+L K R
Sbjct: 202 GVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH--VSKECKDLITRMLQRDPKRRAY 259
Query: 151 IPQILADPWL---NPNQQSKHDETDLQEHAKTSKEEIKSV 41
+ +I PWL +P+ +K++ L + S+EE S+
Sbjct: 260 LEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSEEEHNSI 298
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 132 bits (319), Expect = 1e-30
Identities = 79/220 (35%), Positives = 127/220 (57%), Gaps = 8/220 (3%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
+Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN++
Sbjct: 88 LYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFAQIVHAISYCHKLHVVHRDLKPENVVF 147
Query: 499 --DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
GL +KL+DFGF+ K T CGS AY++PEIL G Y D+WS+
Sbjct: 148 FEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIWSL 201
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKVSAECRKLITRIL-APLKMRVK 152
GV+L+ +V G+ PF + N ++ L + + K + P VS EC+ LITR+L K R
Sbjct: 202 GVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH--VSKECKDLITRMLQRDPKRRAS 259
Query: 151 IPQILADPWL---NPNQQSKHDETDLQEHAKTSKEEIKSV 41
+ +I PWL +P+ +K++ L + S+EE S+
Sbjct: 260 LEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSEEEHNSI 298
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 130 bits (315), Expect = 4e-30
Identities = 81/225 (36%), Positives = 122/225 (54%), Gaps = 26/225 (11%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ-----------------------LVE 566
+Y++MEYA G + D + + E R F+Q +V
Sbjct: 128 LYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVS 187
Query: 565 AVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYA 386
AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA
Sbjct: 188 AVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT-----VGGKLDTFCGSPPYA 242
Query: 385 SPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVS 209
+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P +S
Sbjct: 243 APELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMS 300
Query: 208 AECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 80
+C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 301 TDCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 340
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 129 bits (312), Expect = 9e-30
Identities = 76/197 (38%), Positives = 113/197 (57%), Gaps = 6/197 (3%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
Y+VME G+L+ I + + ++E+ RR+ +QL+ AV++ H GVVHRD+K ENLL+D
Sbjct: 137 YLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDE 196
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETF---CGSYAYASPEILKGVPYRPQDSDVWSMG 323
NIKL DFG + G+ S+ F CGS AYA+PE+L Y P+ DVWS+G
Sbjct: 197 DNNIKLIDFGLSN-----CAGILGYSDPFSTQCGSPAYAAPELLARKKYGPK-IDVWSIG 250
Query: 322 VVLYAIVYGRLPF--DDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPLKM-RVK 152
V +YA++ G LPF + + L +++ +K P ++S + +L P + R
Sbjct: 251 VNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPN 310
Query: 151 IPQILADPWLNPNQQSK 101
I Q LA+ WLN N K
Sbjct: 311 IQQALANRWLNENYTGK 327
>AB183428-1|BAF73616.1| 580|Homo sapiens maternal embryonic luecine
zipper kinase v3 protein.
Length = 580
Score = 128 bits (309), Expect = 2e-29
Identities = 71/192 (36%), Positives = 104/192 (54%), Gaps = 2/192 (1%)
Frame = -2
Query: 691 NFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCE 512
N + ++ +Y G L D I + E R F+Q+V AV Y H +G HRD+K E
Sbjct: 6 NIMNYMKLLGQYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPE 65
Query: 511 NLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 332
NLL D +KL DFG KPK +T CGS AYA+PE+++G Y ++DVW
Sbjct: 66 NLLFDEYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVW 122
Query: 331 SMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMR 158
SMG++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L K R
Sbjct: 123 SMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKR 180
Query: 157 VKIPQILADPWL 122
+ + +L PW+
Sbjct: 181 ISMKNLLNHPWI 192
>BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein.
Length = 1102
Score = 122 bits (295), Expect = 1e-27
Identities = 71/164 (43%), Positives = 95/164 (57%), Gaps = 3/164 (1%)
Frame = -2
Query: 604 ETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVF 425
E RR FKQ+V AV +CH R +VHRD+K ENLL+D LNIK++DFGF+ +
Sbjct: 3 EKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ---- 58
Query: 424 ALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV- 248
L +T+CGS YA+PE+ +G Y D+WS+GVVLY +V G LPFD + L +V
Sbjct: 59 -LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVL 117
Query: 247 QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIPQILADPWL 122
K P +S EC LI +L P K R+ + QI W+
Sbjct: 118 SGKFRIPF--FMSTECEHLIRHMLVLDPNK-RLSMEQICKHKWM 158
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 119 bits (287), Expect = 1e-26
Identities = 63/158 (39%), Positives = 91/158 (57%), Gaps = 15/158 (9%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKD---------------QHIDETRGRRWFKQLVEAVDYCHER 542
+++VMEY G L D I K+ + +DE RR F+Q++ VDYCH
Sbjct: 100 IFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELDEKESRRLFQQILSGVDYCHRH 159
Query: 541 GVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGV 362
VVHRD+K EN+L+D +N K++DFG + +G F T CGS YA+PE++ G
Sbjct: 160 MVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGR 214
Query: 361 PYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV 248
Y + D+WS GV+LYA++ G LPFDD + L K++
Sbjct: 215 LYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKI 252
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 116 bits (280), Expect = 7e-26
Identities = 63/193 (32%), Positives = 114/193 (59%), Gaps = 3/193 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G L ++K + +DE R +++ +A+ YCH++ V+HRDIK ENLL+
Sbjct: 82 VYLILEYAPRGELYKELQKSEKLDEQRTATIIEEVADALTYCHDKKVIHRDIKPENLLLG 141
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ P+ +T CG+ Y PE+++G Y + D+W +GV+
Sbjct: 142 FRGEVKIADFGWSVHTPLPER------KTMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVL 194
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVKIP 146
Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+ +
Sbjct: 195 CYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLPLA 251
Query: 145 QILADPWLNPNQQ 107
QIL PW+ + +
Sbjct: 252 QILKHPWVQAHSR 264
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 115 bits (276), Expect = 2e-25
Identities = 64/193 (33%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G L ++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL+
Sbjct: 82 VYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLG 141
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ H +T CG+ Y PE+++G Y + D+W +GV+
Sbjct: 142 FRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVL 194
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVKIP 146
Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+ +
Sbjct: 195 CYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLPLA 251
Query: 145 QILADPWLNPNQQ 107
QIL PW+ + +
Sbjct: 252 QILKHPWVQAHSR 264
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 115 bits (276), Expect = 2e-25
Identities = 64/193 (33%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G L ++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL+
Sbjct: 113 VYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLG 172
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ H +T CG+ Y PE+++G Y + D+W +GV+
Sbjct: 173 FRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVL 225
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVKIP 146
Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+ +
Sbjct: 226 CYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLPLA 282
Query: 145 QILADPWLNPNQQ 107
QIL PW+ + +
Sbjct: 283 QILKHPWVQAHSR 295
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 115 bits (276), Expect = 2e-25
Identities = 64/193 (33%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G L ++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL+
Sbjct: 97 VYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLG 156
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ H +T CG+ Y PE+++G Y + D+W +GV+
Sbjct: 157 FRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVL 209
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVKIP 146
Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+ +
Sbjct: 210 CYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLPLA 266
Query: 145 QILADPWLNPNQQ 107
QIL PW+ + +
Sbjct: 267 QILKHPWVQAHSR 279
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 115 bits (276), Expect = 2e-25
Identities = 64/193 (33%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G L ++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL+
Sbjct: 116 VYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLG 175
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ H +T CG+ Y PE+++G Y + D+W +GV+
Sbjct: 176 FRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVL 228
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVKIP 146
Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+ +
Sbjct: 229 CYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLPLA 285
Query: 145 QILADPWLNPNQQ 107
QIL PW+ + +
Sbjct: 286 QILKHPWVQAHSR 298
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 115 bits (276), Expect = 2e-25
Identities = 64/193 (33%), Positives = 113/193 (58%), Gaps = 3/193 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G L ++K + +DE R ++L +A+ YCH++ V+HRDIK ENLL+
Sbjct: 116 VYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLG 175
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ H +T CG+ Y PE+++G Y + D+W +GV+
Sbjct: 176 FRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVL 228
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL--APLKMRVKIP 146
Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L PL+ R+ +
Sbjct: 229 CYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLLRYQPLE-RLPLA 285
Query: 145 QILADPWLNPNQQ 107
QIL PW+ + +
Sbjct: 286 QILKHPWVQAHSR 298
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 113 bits (272), Expect = 6e-25
Identities = 68/188 (36%), Positives = 98/188 (52%), Gaps = 3/188 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D
Sbjct: 81 YLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDE 140
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS G+VL
Sbjct: 141 RDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVL 198
Query: 313 YAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRVKIPQ 143
A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+ IP
Sbjct: 199 TAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPD 258
Query: 142 ILADPWLN 119
I D W N
Sbjct: 259 IKKDRWYN 266
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 113 bits (272), Expect = 6e-25
Identities = 68/188 (36%), Positives = 98/188 (52%), Gaps = 3/188 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D
Sbjct: 81 YLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDE 140
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS G+VL
Sbjct: 141 RDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVL 198
Query: 313 YAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRVKIPQ 143
A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+ IP
Sbjct: 199 TAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPD 258
Query: 142 ILADPWLN 119
I D W N
Sbjct: 259 IKKDRWYN 266
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 113 bits (272), Expect = 6e-25
Identities = 68/188 (36%), Positives = 98/188 (52%), Gaps = 3/188 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D
Sbjct: 81 YLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDE 140
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS G+VL
Sbjct: 141 RDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVL 198
Query: 313 YAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRVKIPQ 143
A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+ IP
Sbjct: 199 TAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPD 258
Query: 142 ILADPWLN 119
I D W N
Sbjct: 259 IKKDRWYN 266
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 113 bits (272), Expect = 6e-25
Identities = 68/188 (36%), Positives = 98/188 (52%), Gaps = 3/188 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D
Sbjct: 81 YLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDE 140
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS G+VL
Sbjct: 141 RDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVL 198
Query: 313 YAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRVKIPQ 143
A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+ IP
Sbjct: 199 TAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPD 258
Query: 142 ILADPWLN 119
I D W N
Sbjct: 259 IKKDRWYN 266
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 113 bits (272), Expect = 6e-25
Identities = 68/188 (36%), Positives = 98/188 (52%), Gaps = 3/188 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D
Sbjct: 81 YLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDE 140
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS G+VL
Sbjct: 141 RDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVL 198
Query: 313 YAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRVKIPQ 143
A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+ IP
Sbjct: 199 TAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPD 258
Query: 142 ILADPWLN 119
I D W N
Sbjct: 259 IKKDRWYN 266
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 113 bits (272), Expect = 6e-25
Identities = 68/188 (36%), Positives = 98/188 (52%), Gaps = 3/188 (1%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
Y+ +EY G L D I D + E +R+F QL+ V Y H G+ HRDIK ENLL+D
Sbjct: 81 YLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDE 140
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
N+K+SDFG A + N L CG+ Y +PE+LK + + DVWS G+VL
Sbjct: 141 RDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVL 198
Query: 313 YAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAECRKLITRILAP-LKMRVKIPQ 143
A++ G LP+D ++ Q + K ++ K+ + L+ +IL R+ IP
Sbjct: 199 TAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPD 258
Query: 142 ILADPWLN 119
I D W N
Sbjct: 259 IKKDRWYN 266
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 112 bits (270), Expect = 1e-24
Identities = 64/187 (34%), Positives = 98/187 (52%), Gaps = 2/187 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+++VMEYA G L I + + E + F Q+V AV + HE ++HRD+K EN+
Sbjct: 146 LHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYT 205
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K+ DFGF+ K + + TFCGS YA+PE+ + Y D+W++GV+
Sbjct: 206 SNTCVKVGDFGFSTVSKKGE-----MLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVL 260
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILAPLKM-RVKIPQ 143
LY +V G +PF +L K + + S P P VS C +LI +L + R I
Sbjct: 261 LYFMVTGTMPFRAETVAKLKKSILEGTYSVP--PHVSEPCHRLIRGVLQQIPTERYGIDC 318
Query: 142 ILADPWL 122
I+ D W+
Sbjct: 319 IMNDEWM 325
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 112 bits (270), Expect = 1e-24
Identities = 62/206 (30%), Positives = 109/206 (52%), Gaps = 1/206 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL+
Sbjct: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + + T CG+ Y PE+++G + D+WS+GV+
Sbjct: 266 SAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVL 318
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R + ++
Sbjct: 319 CYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
Query: 139 LADPWLNPNQQSKHDETDLQEHAKTS 62
L PW+ N + + + +K S
Sbjct: 378 LEHPWITANSSKPSNCQNKESASKQS 403
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 112 bits (270), Expect = 1e-24
Identities = 62/206 (30%), Positives = 109/206 (52%), Gaps = 1/206 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL+
Sbjct: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + + T CG+ Y PE+++G + D+WS+GV+
Sbjct: 266 SAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVL 318
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R + ++
Sbjct: 319 CYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
Query: 139 LADPWLNPNQQSKHDETDLQEHAKTS 62
L PW+ N + + + +K S
Sbjct: 378 LEHPWITANSSKPSNCQNKESASKQS 403
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 112 bits (270), Expect = 1e-24
Identities = 62/206 (30%), Positives = 109/206 (52%), Gaps = 1/206 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL+
Sbjct: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + + T CG+ Y PE+++G + D+WS+GV+
Sbjct: 266 SAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVL 318
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R + ++
Sbjct: 319 CYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
Query: 139 LADPWLNPNQQSKHDETDLQEHAKTS 62
L PW+ N + + + +K S
Sbjct: 378 LEHPWITANSSKPSNCQNKESASKQS 403
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 112 bits (270), Expect = 1e-24
Identities = 62/206 (30%), Positives = 109/206 (52%), Gaps = 1/206 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL+
Sbjct: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + + T CG+ Y PE+++G + D+WS+GV+
Sbjct: 266 SAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVL 318
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R + ++
Sbjct: 319 CYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
Query: 139 LADPWLNPNQQSKHDETDLQEHAKTS 62
L PW+ N + + + +K S
Sbjct: 378 LEHPWITANSSKPSNCQNKESASKQS 403
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 112 bits (270), Expect = 1e-24
Identities = 62/206 (30%), Positives = 109/206 (52%), Gaps = 1/206 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL+
Sbjct: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + + T CG+ Y PE+++G + D+WS+GV+
Sbjct: 266 SAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVL 318
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R + ++
Sbjct: 319 CYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
Query: 139 LADPWLNPNQQSKHDETDLQEHAKTS 62
L PW+ N + + + +K S
Sbjct: 378 LEHPWITANSSKPSNCQNKESASKQS 403
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 112 bits (270), Expect = 1e-24
Identities = 62/206 (30%), Positives = 109/206 (52%), Gaps = 1/206 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL+
Sbjct: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + + T CG+ Y PE+++G + D+WS+GV+
Sbjct: 266 SAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVL 318
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R + ++
Sbjct: 319 CYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
Query: 139 LADPWLNPNQQSKHDETDLQEHAKTS 62
L PW+ N + + + +K S
Sbjct: 378 LEHPWITANSSKPSNCQNKESASKQS 403
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 112 bits (270), Expect = 1e-24
Identities = 62/206 (30%), Positives = 109/206 (52%), Gaps = 1/206 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL+
Sbjct: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + + T CG+ Y PE+++G + D+WS+GV+
Sbjct: 266 SAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVL 318
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R + ++
Sbjct: 319 CYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
Query: 139 LADPWLNPNQQSKHDETDLQEHAKTS 62
L PW+ N + + + +K S
Sbjct: 378 LEHPWITANSSKPSNCQNKESASKQS 403
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 112 bits (270), Expect = 1e-24
Identities = 62/206 (30%), Positives = 109/206 (52%), Gaps = 1/206 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G++ ++K DE R + +L A+ YCH + V+HRDIK ENLL+
Sbjct: 206 VYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLG 265
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + + T CG+ Y PE+++G + D+WS+GV+
Sbjct: 266 SAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVL 318
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R + ++
Sbjct: 319 CYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 377
Query: 139 LADPWLNPNQQSKHDETDLQEHAKTS 62
L PW+ N + + + +K S
Sbjct: 378 LEHPWITANSSKPSNCQNKESASKQS 403
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 111 bits (268), Expect = 2e-24
Identities = 61/206 (29%), Positives = 109/206 (52%), Gaps = 1/206 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+++EYA G++ ++K DE R + ++ A+ YCH + V+HRDIK ENLL+
Sbjct: 205 VYLILEYAPLGTVYRELQKLSKFDEQRTANLYNRIANALSYCHSKRVIHRDIKPENLLLG 264
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + + T CG+ Y PE+++G + D+WS+GV+
Sbjct: 265 SAGELKIADFGWS------VHAPSSRRTTLCGTLDYLPPEMIEG-RMHDEKVDLWSLGVL 317
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y + G+ PF+ Y + K++ ++V F V+ R LI+R+L R + ++
Sbjct: 318 CYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREV 376
Query: 139 LADPWLNPNQQSKHDETDLQEHAKTS 62
L PW+ N + + + +K S
Sbjct: 377 LEHPWITANSSKPSNCQNKESASKQS 402
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 111 bits (267), Expect = 3e-24
Identities = 60/165 (36%), Positives = 98/165 (59%), Gaps = 4/165 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
+Y+++E + G + D I K ++ ++E +++F Q+V A+ YCH+ VVHRD+K EN++
Sbjct: 88 LYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKLHVVHRDLKPENVVF 147
Query: 499 --DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
GL +KL+DFGF+ K T CGS AY++PEIL G Y D+WS+
Sbjct: 148 FEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAYSAPEILLGDEYDAPAVDIWSL 201
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKVSAECRK 194
GV+L+ +V + PF + N ++ L + + K + P VS EC++
Sbjct: 202 GVILFMLVCEQPPFQEANDSETLTMIMDCKYTVPSH--VSKECKE 244
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 109 bits (263), Expect = 8e-24
Identities = 55/151 (36%), Positives = 94/151 (62%), Gaps = 1/151 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++ VME+ G L+ I+K + DE R R + +++ A+ + H++G+++RD+K +N+L+D
Sbjct: 428 LFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLD 487
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
H + KL+DFG + + NGV + TFCG+ Y +PEIL+ + Y P D W+MGV+
Sbjct: 488 HEGHCKLADFGMCKEGI--CNGV--TTATFCGTPDYIAPEILQEMLYGPA-VDWWAMGVL 542
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 227
LY ++ G PF+ N L + + N +V +P
Sbjct: 543 LYEMLCGHAPFEAENEDDLFEAILNDEVVYP 573
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 109 bits (263), Expect = 8e-24
Identities = 70/192 (36%), Positives = 101/192 (52%), Gaps = 7/192 (3%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+VME A G L D I E R + +++ V Y H G+ HRD+K ENLL
Sbjct: 168 VYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYY 227
Query: 496 H-GLNIK--LSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
H G + K ++DFG A K G L +T CG+ Y +PE+L PY D+W++
Sbjct: 228 HPGTDSKIIITDFGLASAR---KKGDDCLMKTTCGTPEYIAPEVLVRKPY-TNSVDMWAL 283
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITRIL-APLKMR 158
GV+ Y ++ G +PF+D N T+L +Q+ + K S+ E P VS + I R+L R
Sbjct: 284 GVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGAR 343
Query: 157 VKIPQILADPWL 122
+ Q L PW+
Sbjct: 344 MTALQALRHPWV 355
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 109 bits (263), Expect = 8e-24
Identities = 55/151 (36%), Positives = 94/151 (62%), Gaps = 1/151 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++ VME+ G L+ I+K + DE R R + +++ A+ + H++G+++RD+K +N+L+D
Sbjct: 429 LFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLD 488
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
H + KL+DFG + + NGV + TFCG+ Y +PEIL+ + Y P D W+MGV+
Sbjct: 489 HEGHCKLADFGMCKEGI--CNGV--TTATFCGTPDYIAPEILQEMLYGPA-VDWWAMGVL 543
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 227
LY ++ G PF+ N L + + N +V +P
Sbjct: 544 LYEMLCGHAPFEAENEDDLFEAILNDEVVYP 574
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 109 bits (263), Expect = 8e-24
Identities = 70/192 (36%), Positives = 101/192 (52%), Gaps = 7/192 (3%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+VME A G L D I E R + +++ V Y H G+ HRD+K ENLL
Sbjct: 168 VYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYY 227
Query: 496 H-GLNIK--LSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
H G + K ++DFG A K G L +T CG+ Y +PE+L PY D+W++
Sbjct: 228 HPGTDSKIIITDFGLASAR---KKGDDCLMKTTCGTPEYIAPEVLVRKPY-TNSVDMWAL 283
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITRIL-APLKMR 158
GV+ Y ++ G +PF+D N T+L +Q+ + K S+ E P VS + I R+L R
Sbjct: 284 GVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGAR 343
Query: 157 VKIPQILADPWL 122
+ Q L PW+
Sbjct: 344 MTALQALRHPWV 355
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 108 bits (260), Expect = 2e-23
Identities = 60/165 (36%), Positives = 100/165 (60%), Gaps = 1/165 (0%)
Frame = -2
Query: 667 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 488
VMEYA G L + +++ E R R + ++V A++Y H R VV+RDIK ENL++D
Sbjct: 228 VMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDG 287
Query: 487 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYA 308
+IK++DFG + + +G A +TFCG+ Y +PE+L+ Y + D W +GVV+Y
Sbjct: 288 HIKITDFGLCKEGI--SDG--ATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYE 342
Query: 307 IVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
++ GRLPF + ++ +L + + ++ FPR +S E + L+ +L
Sbjct: 343 MMCGRLPFYNQDHERLFELILMEEIRFPR--TLSPEAKSLLAGLL 385
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 108 bits (260), Expect = 2e-23
Identities = 60/165 (36%), Positives = 100/165 (60%), Gaps = 1/165 (0%)
Frame = -2
Query: 667 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 488
VMEYA G L + +++ E R R + ++V A++Y H R VV+RDIK ENL++D
Sbjct: 228 VMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDG 287
Query: 487 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYA 308
+IK++DFG + + +G A +TFCG+ Y +PE+L+ Y + D W +GVV+Y
Sbjct: 288 HIKITDFGLCKEGI--SDG--ATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYE 342
Query: 307 IVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
++ GRLPF + ++ +L + + ++ FPR +S E + L+ +L
Sbjct: 343 MMCGRLPFYNQDHERLFELILMEEIRFPR--TLSPEAKSLLAGLL 385
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 108 bits (260), Expect = 2e-23
Identities = 60/165 (36%), Positives = 100/165 (60%), Gaps = 1/165 (0%)
Frame = -2
Query: 667 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 488
VMEYA G L + +++ E R R + ++V A++Y H R VV+RDIK ENL++D
Sbjct: 228 VMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDG 287
Query: 487 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYA 308
+IK++DFG + + +G A +TFCG+ Y +PE+L+ Y + D W +GVV+Y
Sbjct: 288 HIKITDFGLCKEGI--SDG--ATMKTFCGTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYE 342
Query: 307 IVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
++ GRLPF + ++ +L + + ++ FPR +S E + L+ +L
Sbjct: 343 MMCGRLPFYNQDHERLFELILMEEIRFPR--TLSPEAKSLLAGLL 385
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 107 bits (258), Expect = 3e-23
Identities = 63/179 (35%), Positives = 106/179 (59%), Gaps = 2/179 (1%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH-ERGVVH 530
LK S + VMEYA G L + +++ E R R + ++V A+DY H E+ VV+
Sbjct: 213 LKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVY 272
Query: 529 RDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRP 350
RD+K ENL++D +IK++DFG + + K+G A +TFCG+ Y +PE+L+ Y
Sbjct: 273 RDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTPEYLAPEVLEDNDY-G 327
Query: 349 QDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR + E + L++ +L
Sbjct: 328 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR--TLGPEAKSLLSGLL 384
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 107 bits (258), Expect = 3e-23
Identities = 63/179 (35%), Positives = 106/179 (59%), Gaps = 2/179 (1%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH-ERGVVH 530
LK S + VMEYA G L + +++ E R R + ++V A+DY H E+ VV+
Sbjct: 213 LKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVY 272
Query: 529 RDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRP 350
RD+K ENL++D +IK++DFG + + K+G A +TFCG+ Y +PE+L+ Y
Sbjct: 273 RDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTPEYLAPEVLEDNDY-G 327
Query: 349 QDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR + E + L++ +L
Sbjct: 328 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR--TLGPEAKSLLSGLL 384
>BC043487-1|AAH43487.1| 505|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 1,
alpha protein.
Length = 505
Score = 107 bits (258), Expect = 3e-23
Identities = 63/216 (29%), Positives = 117/216 (54%), Gaps = 5/216 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V + G ++++ D+ E + R + + ++ ++Y H + +VHRDIK NLL+
Sbjct: 226 LYLVFDLLRKGPVMEV-PCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLG 284
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL--KGVPYRPQDSDVWSMG 323
++K++DFG + G A + G+ A+ +PE + G + + DVW+ G
Sbjct: 285 DDGHVKIADFGVSNQF----EGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATG 340
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY VYG+ PF D L ++++N+ V FP EP++S E + LI ++L + R+ +
Sbjct: 341 VTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGV 400
Query: 148 PQILADPWLNPN-QQSKHDETDLQEHAKTSKEEIKS 44
P I PW+ N ++ E + + ++EE+K+
Sbjct: 401 PDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKN 436
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 107 bits (258), Expect = 3e-23
Identities = 63/179 (35%), Positives = 106/179 (59%), Gaps = 2/179 (1%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH-ERGVVH 530
LK S + VMEYA G L + +++ E R R + ++V A+DY H E+ VV+
Sbjct: 213 LKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVY 272
Query: 529 RDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRP 350
RD+K ENL++D +IK++DFG + + K+G A +TFCG+ Y +PE+L+ Y
Sbjct: 273 RDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTPEYLAPEVLEDNDY-G 327
Query: 349 QDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR + E + L++ +L
Sbjct: 328 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR--TLGPEAKSLLSGLL 384
>AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein
protein.
Length = 505
Score = 107 bits (258), Expect = 3e-23
Identities = 63/216 (29%), Positives = 117/216 (54%), Gaps = 5/216 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V + G ++++ D+ E + R + + ++ ++Y H + +VHRDIK NLL+
Sbjct: 226 LYLVFDLLRKGPVMEV-PCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLG 284
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL--KGVPYRPQDSDVWSMG 323
++K++DFG + G A + G+ A+ +PE + G + + DVW+ G
Sbjct: 285 DDGHVKIADFGVSNQF----EGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATG 340
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY VYG+ PF D L ++++N+ V FP EP++S E + LI ++L + R+ +
Sbjct: 341 VTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGV 400
Query: 148 PQILADPWLNPN-QQSKHDETDLQEHAKTSKEEIKS 44
P I PW+ N ++ E + + ++EE+K+
Sbjct: 401 PDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKN 436
>AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein
protein.
Length = 505
Score = 107 bits (258), Expect = 3e-23
Identities = 63/216 (29%), Positives = 117/216 (54%), Gaps = 5/216 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V + G ++++ D+ E + R + + ++ ++Y H + +VHRDIK NLL+
Sbjct: 226 LYLVFDLLRKGPVMEV-PCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLG 284
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL--KGVPYRPQDSDVWSMG 323
++K++DFG + G A + G+ A+ +PE + G + + DVW+ G
Sbjct: 285 DDGHVKIADFGVSNQF----EGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATG 340
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY VYG+ PF D L ++++N+ V FP EP++S E + LI ++L + R+ +
Sbjct: 341 VTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGV 400
Query: 148 PQILADPWLNPN-QQSKHDETDLQEHAKTSKEEIKS 44
P I PW+ N ++ E + + ++EE+K+
Sbjct: 401 PDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKN 436
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 107 bits (258), Expect = 3e-23
Identities = 63/179 (35%), Positives = 106/179 (59%), Gaps = 2/179 (1%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH-ERGVVH 530
LK S + VMEYA G L + +++ E R R + ++V A+DY H E+ VV+
Sbjct: 213 LKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVY 272
Query: 529 RDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRP 350
RD+K ENL++D +IK++DFG + + K+G A +TFCG+ Y +PE+L+ Y
Sbjct: 273 RDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTPEYLAPEVLEDNDY-G 327
Query: 349 QDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR + E + L++ +L
Sbjct: 328 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR--TLGPEAKSLLSGLL 384
>AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta protein.
Length = 588
Score = 107 bits (257), Expect = 4e-23
Identities = 58/189 (30%), Positives = 107/189 (56%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL + G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNYVGTPAFMAPESLSETRKIFSGKAKDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQILADPWL 122
P+I PW+
Sbjct: 438 PEIKLHPWV 446
>X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B
protein.
Length = 417
Score = 107 bits (256), Expect = 6e-23
Identities = 63/179 (35%), Positives = 106/179 (59%), Gaps = 2/179 (1%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCH-ERGVVH 530
LK S + VMEYA G L + +++ E R R + ++V A+DY H E+ VV+
Sbjct: 150 LKYSFQTHDRLCFVMEYANGGELFFHLSRERVFAEDRARFYGAEIVSALDYLHSEKNVVY 209
Query: 529 RDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRP 350
RD+K ENL++D +IK++DFG + + K+G A +TFCG+ Y +PE+L+ Y
Sbjct: 210 RDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTPEYLAPEVLEDNDY-G 264
Query: 349 QDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR + E + L++ +L
Sbjct: 265 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR--TLGPEAKSLLSGLL 321
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase RLPK
protein.
Length = 802
Score = 107 bits (256), Expect = 6e-23
Identities = 73/204 (35%), Positives = 112/204 (54%), Gaps = 15/204 (7%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM-- 500
++VME G L + I+K +H ET ++LV AV + H+ GVVHRD+K ENLL
Sbjct: 495 FLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTD 554
Query: 499 -DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 323
+ L IK+ DFGFAR +KP + +T C + YA+PE+L Y + D+WS+G
Sbjct: 555 ENDNLEIKIIDFGFAR--LKPPDN--QPLKTPCFTLHYAAPELLNQNGY-DESCDLWSLG 609
Query: 322 VVLYAIVYGRLPFDD-------TNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITRILA 173
V+LY ++ G++PF T+ +++K++ + SF E VS E + LI +L
Sbjct: 610 VILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLT 669
Query: 172 --PLKMRVKIPQILADPWLNPNQQ 107
P K R+K+ + + WL Q
Sbjct: 670 VDPNK-RLKMSGLRYNEWLQDGSQ 692
Score = 83.0 bits (196), Expect = 1e-15
Identities = 45/171 (26%), Positives = 95/171 (55%), Gaps = 4/171 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++++++Y G L + + + E + + ++V A+++ H+ G+++RDIK EN+L+D
Sbjct: 127 LHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLD 186
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPY-RPQDSDVWSMGV 320
++ L+DFG ++ + + + +FCG+ Y +P+I++G + D WS+GV
Sbjct: 187 SNGHVVLTDFGLSKEFVADET---ERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGV 243
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKV--SFPREP-KVSAECRKLITRIL 176
++Y ++ G PF ++ ++ S P P ++SA + LI R+L
Sbjct: 244 LMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLL 294
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 107 bits (256), Expect = 6e-23
Identities = 73/204 (35%), Positives = 112/204 (54%), Gaps = 15/204 (7%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM-- 500
++VME G L + I+K +H ET ++LV AV + H+ GVVHRD+K ENLL
Sbjct: 495 FLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTD 554
Query: 499 -DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 323
+ L IK+ DFGFAR +KP + +T C + YA+PE+L Y + D+WS+G
Sbjct: 555 ENDNLEIKIIDFGFAR--LKPPDN--QPLKTPCFTLHYAAPELLNQNGY-DESCDLWSLG 609
Query: 322 VVLYAIVYGRLPFDD-------TNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITRILA 173
V+LY ++ G++PF T+ +++K++ + SF E VS E + LI +L
Sbjct: 610 VILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLT 669
Query: 172 --PLKMRVKIPQILADPWLNPNQQ 107
P K R+K+ + + WL Q
Sbjct: 670 VDPNK-RLKMSGLRYNEWLQDGSQ 692
Score = 83.0 bits (196), Expect = 1e-15
Identities = 45/171 (26%), Positives = 95/171 (55%), Gaps = 4/171 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++++++Y G L + + + E + + ++V A+++ H+ G+++RDIK EN+L+D
Sbjct: 127 LHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLD 186
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPY-RPQDSDVWSMGV 320
++ L+DFG ++ + + + +FCG+ Y +P+I++G + D WS+GV
Sbjct: 187 SNGHVVLTDFGLSKEFVADET---ERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGV 243
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKV--SFPREP-KVSAECRKLITRIL 176
++Y ++ G PF ++ ++ S P P ++SA + LI R+L
Sbjct: 244 LMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLL 294
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 105 bits (253), Expect = 1e-22
Identities = 69/235 (29%), Positives = 120/235 (51%), Gaps = 13/235 (5%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM- 500
+Y+VME E+G L +I+ + H E R + L A+ Y H +VHRD+K EN+++
Sbjct: 188 MYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVK 247
Query: 499 --------DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 344
+ LNIK++DFG A +K ++ A+ + CG+ Y +PE++ Y Q
Sbjct: 248 SSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQATCGTPIYMAPEVISAHDY-SQQ 303
Query: 343 SDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVS-AECRKLITRILAP 170
D+WS+GVV+Y ++ G PF ++ +L + + + ++ F S ++C K + + L
Sbjct: 304 CDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMK 363
Query: 169 L--KMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTSKEEIKSVNIGTVTYDRK 11
+ R+ ++L + WL N+ S T++ E K K +SV T K
Sbjct: 364 VDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNK 418
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 105 bits (253), Expect = 1e-22
Identities = 69/235 (29%), Positives = 120/235 (51%), Gaps = 13/235 (5%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM- 500
+Y+VME E+G L +I+ + H E R + L A+ Y H +VHRD+K EN+++
Sbjct: 188 MYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVK 247
Query: 499 --------DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 344
+ LNIK++DFG A +K ++ A+ + CG+ Y +PE++ Y Q
Sbjct: 248 SSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQATCGTPIYMAPEVISAHDY-SQQ 303
Query: 343 SDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVS-AECRKLITRILAP 170
D+WS+GVV+Y ++ G PF ++ +L + + + ++ F S ++C K + + L
Sbjct: 304 CDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMK 363
Query: 169 L--KMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTSKEEIKSVNIGTVTYDRK 11
+ R+ ++L + WL N+ S T++ E K K +SV T K
Sbjct: 364 VDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNK 418
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 105 bits (253), Expect = 1e-22
Identities = 69/235 (29%), Positives = 120/235 (51%), Gaps = 13/235 (5%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM- 500
+Y+VME E+G L +I+ + H E R + L A+ Y H +VHRD+K EN+++
Sbjct: 188 MYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKLENIMVK 247
Query: 499 --------DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 344
+ LNIK++DFG A +K ++ A+ + CG+ Y +PE++ Y Q
Sbjct: 248 SSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQATCGTPIYMAPEVISAHDY-SQQ 303
Query: 343 SDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVS-AECRKLITRILAP 170
D+WS+GVV+Y ++ G PF ++ +L + + + ++ F S ++C K + + L
Sbjct: 304 CDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQLMK 363
Query: 169 L--KMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTSKEEIKSVNIGTVTYDRK 11
+ R+ ++L + WL N+ S T++ E K K +SV T K
Sbjct: 364 VDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNK 418
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 105 bits (253), Expect = 1e-22
Identities = 59/178 (33%), Positives = 102/178 (57%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL++D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing
serine/threonine kinase protein.
Length = 1323
Score = 105 bits (251), Expect = 2e-22
Identities = 64/185 (34%), Positives = 101/185 (54%), Gaps = 2/185 (1%)
Frame = -2
Query: 670 IVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
+VME +G L I + +DE F+QLV AV Y + ++HRDIK EN+++
Sbjct: 1079 LVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAE 1138
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
IKL DFG A + K L TFCG+ Y +PE+L G PYR + ++WS+GV L
Sbjct: 1139 DFTIKLIDFGSAAYLERGK-----LFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTL 1193
Query: 313 YAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPL-KMRVKIPQIL 137
Y +V F++ + +L + V+ + P VS E L++ +L P+ + R + +++
Sbjct: 1194 YTLV-----FEENPFCELEETVEAAIHPPY--LVSKELMSLVSGLLQPVPERRTTLEKLV 1246
Query: 136 ADPWL 122
DPW+
Sbjct: 1247 TDPWV 1251
>BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein.
Length = 953
Score = 105 bits (251), Expect = 2e-22
Identities = 64/185 (34%), Positives = 101/185 (54%), Gaps = 2/185 (1%)
Frame = -2
Query: 670 IVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
+VME +G L I + +DE F+QLV AV Y + ++HRDIK EN+++
Sbjct: 709 LVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAE 768
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
IKL DFG A + K L TFCG+ Y +PE+L G PYR + ++WS+GV L
Sbjct: 769 DFTIKLIDFGSAAYLERGK-----LFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTL 823
Query: 313 YAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPL-KMRVKIPQIL 137
Y +V F++ + +L + V+ + P VS E L++ +L P+ + R + +++
Sbjct: 824 YTLV-----FEENPFCELEETVEAAIHPPY--LVSKELMSLVSGLLQPVPERRTTLEKLV 876
Query: 136 ADPWL 122
DPW+
Sbjct: 877 TDPWV 881
>AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein.
Length = 1323
Score = 105 bits (251), Expect = 2e-22
Identities = 64/185 (34%), Positives = 101/185 (54%), Gaps = 2/185 (1%)
Frame = -2
Query: 670 IVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
+VME +G L I + +DE F+QLV AV Y + ++HRDIK EN+++
Sbjct: 1079 LVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDIKDENIVIAE 1138
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
IKL DFG A + K L TFCG+ Y +PE+L G PYR + ++WS+GV L
Sbjct: 1139 DFTIKLIDFGSAAYLERGK-----LFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTL 1193
Query: 313 YAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPL-KMRVKIPQIL 137
Y +V F++ + +L + V+ + P VS E L++ +L P+ + R + +++
Sbjct: 1194 YTLV-----FEENPFCELEETVEAAIHPPY--LVSKELMSLVSGLLQPVPERRTTLEKLV 1246
Query: 136 ADPWL 122
DPW+
Sbjct: 1247 TDPWV 1251
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 104 bits (250), Expect = 3e-22
Identities = 59/178 (33%), Positives = 101/178 (56%), Gaps = 1/178 (0%)
Frame = -2
Query: 706 LK*SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHR 527
LK S K + VMEY G L + +++ E R R + ++V A+DY H +V+R
Sbjct: 211 LKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYR 270
Query: 526 DIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
D+K ENL+ D +IK++DFG + + A +TFCG+ Y +PE+L+ Y +
Sbjct: 271 DLKLENLMRDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPEYLAPEVLEDNDY-GR 325
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D W +GVV+Y ++ GRLPF + ++ +L + + + FPR +S++ + L++ +L
Sbjct: 326 AVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--TLSSDAKSLLSGLL 381
>BC026060-1|AAH26060.1| 541|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 2,
beta protein.
Length = 541
Score = 104 bits (250), Expect = 3e-22
Identities = 58/189 (30%), Positives = 106/189 (56%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQILADPWL 122
P+I PW+
Sbjct: 438 PEIKLHPWV 446
>AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein
protein.
Length = 365
Score = 104 bits (250), Expect = 3e-22
Identities = 58/189 (30%), Positives = 106/189 (56%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 72 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 130
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 131 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 186
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 187 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 246
Query: 148 PQILADPWL 122
P+I PW+
Sbjct: 247 PEIKLHPWV 255
>AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens
cDNA FLJ16039 fis, clone ADRGL2001554, weakly similar
to SERINE/THREONINE-PROTEIN KINASE PLK (EC 2.7.1.-). ).
Length = 706
Score = 104 bits (250), Expect = 3e-22
Identities = 55/188 (29%), Positives = 105/188 (55%), Gaps = 5/188 (2%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
Y+++E N +L ++R + + E + + Q+++AV Y H+R ++HRD+K N+ +D
Sbjct: 113 YLILELCSNETLAHLLRVRECLTEPEVQYFLLQIIDAVSYLHKRCIIHRDLKLGNIFLDE 172
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR--PQDSDVWSMGV 320
L +K+ D G A +P +T CG+ Y +PEIL+ R + D+W++GV
Sbjct: 173 NLEVKVGDLGLAAQLNEPNE----RKKTMCGTPNYIAPEILQSNDKRAYSYEVDIWAVGV 228
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP-REPKVSAECRKLITRILAP-LKMRVKI 149
+ Y ++ G+ PFD + +++ +N++SFP ++ +S + R I IL P R+ +
Sbjct: 229 ITYTMLIGKAPFDGGSKEITYRKIRENELSFPIKDHHISHQARMFIRSILNPDPTQRLTL 288
Query: 148 PQILADPW 125
Q++ P+
Sbjct: 289 EQMVQHPF 296
>AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 1 protein.
Length = 588
Score = 104 bits (250), Expect = 3e-22
Identities = 58/189 (30%), Positives = 106/189 (56%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQILADPWL 122
P+I PW+
Sbjct: 438 PEIKLHPWV 446
>AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 2 protein.
Length = 533
Score = 104 bits (250), Expect = 3e-22
Identities = 58/189 (30%), Positives = 106/189 (56%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQILADPWL 122
P+I PW+
Sbjct: 438 PEIKLHPWV 446
>AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 541
Score = 104 bits (250), Expect = 3e-22
Identities = 58/189 (30%), Positives = 106/189 (56%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQILADPWL 122
P+I PW+
Sbjct: 438 PEIKLHPWV 446
>AF287631-1|AAK64601.1| 533|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase b2
protein.
Length = 533
Score = 104 bits (250), Expect = 3e-22
Identities = 58/189 (30%), Positives = 106/189 (56%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQILADPWL 122
P+I PW+
Sbjct: 438 PEIKLHPWV 446
>AF287630-1|AAK64600.1| 588|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase b1
protein.
Length = 588
Score = 104 bits (250), Expect = 3e-22
Identities = 58/189 (30%), Positives = 106/189 (56%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQILADPWL 122
P+I PW+
Sbjct: 438 PEIKLHPWV 446
>AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-dependent
kinase kinase protein.
Length = 417
Score = 104 bits (250), Expect = 3e-22
Identities = 58/189 (30%), Positives = 106/189 (56%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 147 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 205
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 206 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 261
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 262 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 321
Query: 148 PQILADPWL 122
P+I PW+
Sbjct: 322 PEIKLHPWV 330
>AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta-3 protein.
Length = 541
Score = 104 bits (250), Expect = 3e-22
Identities = 58/189 (30%), Positives = 106/189 (56%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQILADPWL 122
P+I PW+
Sbjct: 438 PEIKLHPWV 446
>AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein.
Length = 557
Score = 104 bits (250), Expect = 3e-22
Identities = 58/189 (30%), Positives = 106/189 (56%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 264 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 322
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 323 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 378
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 379 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 438
Query: 148 PQILADPWL 122
P+I PW+
Sbjct: 439 PEIKLHPWV 447
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 104 bits (249), Expect = 4e-22
Identities = 58/168 (34%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+L++
Sbjct: 155 LYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLN 214
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++G +
Sbjct: 215 EDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCI 271
Query: 316 LYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
+Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 272 IYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 317
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 104 bits (249), Expect = 4e-22
Identities = 58/168 (34%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+L++
Sbjct: 155 LYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLN 214
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++G +
Sbjct: 215 EDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCI 271
Query: 316 LYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
+Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 272 IYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 317
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 104 bits (249), Expect = 4e-22
Identities = 58/168 (34%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+L++
Sbjct: 155 LYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLN 214
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++G +
Sbjct: 215 EDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCI 271
Query: 316 LYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
+Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 272 IYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 317
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 104 bits (249), Expect = 4e-22
Identities = 58/168 (34%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+L++
Sbjct: 155 LYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLN 214
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++G +
Sbjct: 215 EDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCI 271
Query: 316 LYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
+Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 272 IYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 317
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 104 bits (249), Expect = 4e-22
Identities = 58/168 (34%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+L++
Sbjct: 147 LYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLN 206
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++G +
Sbjct: 207 EDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCI 263
Query: 316 LYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
+Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 264 IYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 309
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 104 bits (249), Expect = 4e-22
Identities = 58/168 (34%), Positives = 100/168 (59%), Gaps = 1/168 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+L++
Sbjct: 193 LYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLN 252
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++G +
Sbjct: 253 EDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCI 309
Query: 316 LYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
+Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 310 IYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 355
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 103 bits (248), Expect = 5e-22
Identities = 59/203 (29%), Positives = 107/203 (52%), Gaps = 1/203 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+
Sbjct: 150 IYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLG 209
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + +T CG+ Y PE+++G + + D+W +GV+
Sbjct: 210 LKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIGVL 262
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y ++ G PF+ ++ + +++ KV V + LI+++L R+ + Q+
Sbjct: 263 CYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQV 321
Query: 139 LADPWLNPNQQSKHDETDLQEHA 71
A PW+ N + + LQ A
Sbjct: 322 SAHPWVRANSRRVLPPSALQSVA 344
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 103 bits (248), Expect = 5e-22
Identities = 59/203 (29%), Positives = 107/203 (52%), Gaps = 1/203 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+
Sbjct: 150 IYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLG 209
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + +T CG+ Y PE+++G + + D+W +GV+
Sbjct: 210 LKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIGVL 262
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y ++ G PF+ ++ + +++ KV V + LI+++L R+ + Q+
Sbjct: 263 CYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQV 321
Query: 139 LADPWLNPNQQSKHDETDLQEHA 71
A PW+ N + + LQ A
Sbjct: 322 SAHPWVRANSRRVLPPSALQSVA 344
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 103 bits (248), Expect = 5e-22
Identities = 59/203 (29%), Positives = 107/203 (52%), Gaps = 1/203 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+
Sbjct: 150 IYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLG 209
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + +T CG+ Y PE+++G + + D+W +GV+
Sbjct: 210 LKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIGVL 262
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y ++ G PF+ ++ + +++ KV V + LI+++L R+ + Q+
Sbjct: 263 CYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQV 321
Query: 139 LADPWLNPNQQSKHDETDLQEHA 71
A PW+ N + + LQ A
Sbjct: 322 SAHPWVRANSRRVLPPSALQSVA 344
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 103 bits (248), Expect = 5e-22
Identities = 66/195 (33%), Positives = 101/195 (51%), Gaps = 9/195 (4%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDII-RKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
+Y+VMEY G LL ++ R + +DE + + +L+ AV H G VHRDIK EN+L+
Sbjct: 170 LYLVMEYQPGGDLLSLLNRYEDQLDENLIQFYLAELILAVHSVHLMGYVHRDIKPENILV 229
Query: 499 DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL-----KGVPYRPQDSDV 335
D +IKL DFG A K + ++ G+ Y +PE+L G D D
Sbjct: 230 DRTGHIKLVDFGSA---AKMNSNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDW 286
Query: 334 WSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN---KVSFPREPKVSAECRKLITRILAPLK 164
WS+GV+ Y ++YGR PF + + + N + FP +PKVS++ LI +L K
Sbjct: 287 WSVGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQK 346
Query: 163 MRVKIPQILADPWLN 119
R+K + P+ +
Sbjct: 347 ERLKFEGLCCHPFFS 361
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 103 bits (248), Expect = 5e-22
Identities = 66/195 (33%), Positives = 101/195 (51%), Gaps = 9/195 (4%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDII-RKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
+Y+VMEY G LL ++ R + +DE + + +L+ AV H G VHRDIK EN+L+
Sbjct: 170 LYLVMEYQPGGDLLSLLNRYEDQLDENLIQFYLAELILAVHSVHLMGYVHRDIKPENILV 229
Query: 499 DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL-----KGVPYRPQDSDV 335
D +IKL DFG A K + ++ G+ Y +PE+L G D D
Sbjct: 230 DRTGHIKLVDFGSA---AKMNSNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDW 286
Query: 334 WSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN---KVSFPREPKVSAECRKLITRILAPLK 164
WS+GV+ Y ++YGR PF + + + N + FP +PKVS++ LI +L K
Sbjct: 287 WSVGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQK 346
Query: 163 MRVKIPQILADPWLN 119
R+K + P+ +
Sbjct: 347 ERLKFEGLCCHPFFS 361
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 103 bits (248), Expect = 5e-22
Identities = 59/203 (29%), Positives = 107/203 (52%), Gaps = 1/203 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+
Sbjct: 150 IYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLG 209
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + +T CG+ Y PE+++G + + D+W +GV+
Sbjct: 210 LKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIGVL 262
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y ++ G PF+ ++ + +++ KV V + LI+++L R+ + Q+
Sbjct: 263 CYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQV 321
Query: 139 LADPWLNPNQQSKHDETDLQEHA 71
A PW+ N + + LQ A
Sbjct: 322 SAHPWVRANSRRVLPPSALQSVA 344
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 103 bits (248), Expect = 5e-22
Identities = 59/203 (29%), Positives = 107/203 (52%), Gaps = 1/203 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+
Sbjct: 150 IYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLG 209
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + +T CG+ Y PE+++G + + D+W +GV+
Sbjct: 210 LKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIGVL 262
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y ++ G PF+ ++ + +++ KV V + LI+++L R+ + Q+
Sbjct: 263 CYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQV 321
Query: 139 LADPWLNPNQQSKHDETDLQEHA 71
A PW+ N + + LQ A
Sbjct: 322 SAHPWVRANSRRVLPPSALQSVA 344
>U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein
kinase protein.
Length = 458
Score = 103 bits (247), Expect = 7e-22
Identities = 63/185 (34%), Positives = 100/185 (54%), Gaps = 2/185 (1%)
Frame = -2
Query: 670 IVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH 494
+VME +G L I + +DE F+QLV AV Y + ++HRD K EN+++
Sbjct: 214 LVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQLVSAVGYLRLKDIIHRDFKDENIVIAE 273
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVL 314
IKL DFG A + K L TFCG+ Y +PE+L G PYR + ++WS+GV L
Sbjct: 274 DFTIKLIDFGSAAYLERGK-----LFYTFCGTIEYCAPEVLMGNPYRGPELEMWSLGVTL 328
Query: 313 YAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPL-KMRVKIPQIL 137
Y +V F++ + +L + V+ + P VS E L++ +L P+ + R + +++
Sbjct: 329 YTLV-----FEENPFCELEETVEAAIHPPY--LVSKELMSLVSGLLQPVPERRTTLEKLV 381
Query: 136 ADPWL 122
DPW+
Sbjct: 382 TDPWV 386
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 103 bits (247), Expect = 7e-22
Identities = 59/203 (29%), Positives = 107/203 (52%), Gaps = 1/203 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+
Sbjct: 177 IYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLG 236
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + +T CG+ Y PE+++G + + D+W +GV+
Sbjct: 237 LKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIGVL 289
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y ++ G PF+ ++ + +++ KV V + LI+++L R+ + Q+
Sbjct: 290 CYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQV 348
Query: 139 LADPWLNPNQQSKHDETDLQEHA 71
A PW+ N + + LQ A
Sbjct: 349 SAHPWVRANSRRVLPPSALQSVA 371
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 103 bits (247), Expect = 7e-22
Identities = 59/203 (29%), Positives = 107/203 (52%), Gaps = 1/203 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+
Sbjct: 150 IYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLG 209
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + +T CG+ Y PE+++G + + D+W +GV+
Sbjct: 210 LKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCIGVL 262
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y ++ G PF+ ++ + +++ KV V + LI+++L R+ + Q+
Sbjct: 263 CYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQV 321
Query: 139 LADPWLNPNQQSKHDETDLQEHA 71
A PW+ N + + LQ A
Sbjct: 322 SAHPWVRANSRRVLPPSALQSVA 344
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 103 bits (246), Expect = 9e-22
Identities = 66/200 (33%), Positives = 105/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ PY +
Sbjct: 139 PENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKDPY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITASEALKHPWI 272
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 103 bits (246), Expect = 9e-22
Identities = 58/168 (34%), Positives = 99/168 (58%), Gaps = 1/168 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y + YA+NG LL IRK DET R + ++V A +Y H +G++HRD+K EN+L++
Sbjct: 155 LYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSASEYLHGKGIIHRDLKPENILLN 214
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
++I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++G +
Sbjct: 215 EDMHIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCI 271
Query: 316 LYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
+Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 272 IYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 317
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 103 bits (246), Expect = 9e-22
Identities = 58/168 (34%), Positives = 99/168 (58%), Gaps = 1/168 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y + YA+NG LL IRK DET R + ++V A++Y H +G++HRD+K EN+L++
Sbjct: 128 LYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLN 187
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+ I+++DFG A+ + P++ A + +F G+ Y SPE+L + SD+W++G +
Sbjct: 188 EDMYIQITDFGTAK-VLSPESKQ-ARANSFVGTAQYVSPELLT-EKSACKSSDLWALGCI 244
Query: 316 LYAIVYGRLPFDDTN-YTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
+Y +V G PF N Y K ++ + FP K + R L+ ++L
Sbjct: 245 IYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPE--KFFPKARDLVEKLL 290
>AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kinase
protein.
Length = 809
Score = 103 bits (246), Expect = 9e-22
Identities = 71/204 (34%), Positives = 109/204 (53%), Gaps = 15/204 (7%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM-- 500
++VME G L D +RK +H ET ++LV A+ + H+ GVVHRD+K ENLL
Sbjct: 495 FLVMELLNGGELFDALRKKKHFSETEASYIMRKLVSALSHMHDLGVVHRDLKPENLLFTD 554
Query: 499 -DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 323
+ L IK+ DFGFAR +KP + +T C + PE+L Y + D+WS+G
Sbjct: 555 ENDNLEIKIIDFGFAR--LKPPDN--QPLKTPCFTLHSCRPELLNQNGY-DESCDLWSLG 609
Query: 322 VVLYAIVYGRLPFDD-------TNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITRILA 173
V+LY ++ G++PF T+ +++K++ + SF E VS E + LI +L
Sbjct: 610 VILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLT 669
Query: 172 --PLKMRVKIPQILADPWLNPNQQ 107
P K R+K+ + + WL Q
Sbjct: 670 VDPNK-RLKMSGLRYNEWLQDGSQ 692
Score = 83.0 bits (196), Expect = 1e-15
Identities = 45/171 (26%), Positives = 95/171 (55%), Gaps = 4/171 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++++++Y G L + + + E + + ++V A+++ H+ G+++RDIK EN+L+D
Sbjct: 127 LHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLD 186
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPY-RPQDSDVWSMGV 320
++ L+DFG ++ + + + +FCG+ Y +P+I++G + D WS+GV
Sbjct: 187 SNGHVVLTDFGLSKEFVADET---ERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGV 243
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKV--SFPREP-KVSAECRKLITRIL 176
++Y ++ G PF ++ ++ S P P ++SA + LI R+L
Sbjct: 244 LMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLL 294
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 102 bits (245), Expect = 1e-21
Identities = 63/189 (33%), Positives = 100/189 (52%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHI--DETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 503
++IVMEY + G L+ I + + + E + WF Q+ + + H+R ++HRDIK +N+
Sbjct: 76 LFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIF 135
Query: 502 MD-HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
+ +G+ KL DFG AR N L+ T G+ Y SPEI + PY + +D+WS+
Sbjct: 136 LSKNGMVAKLGDFGIAR----VLNNSMELARTCIGTPYYLSPEICQNKPYNNK-TDIWSL 190
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 149
G VLY + + PF+ N QL+ ++ P P S E LI+++ + R I
Sbjct: 191 GCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSI 250
Query: 148 PQILADPWL 122
IL P+L
Sbjct: 251 NSILKRPFL 259
>AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting
kinase short form protein.
Length = 482
Score = 102 bits (245), Expect = 1e-21
Identities = 65/195 (33%), Positives = 101/195 (51%), Gaps = 9/195 (4%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDII-RKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
+Y+VMEY G LL ++ R + +DE + + +L+ AV H G +HRDIK EN+L+
Sbjct: 170 LYLVMEYQPGGDLLSLLNRYEDQLDENLIQFYLAELILAVHSVHLMGYLHRDIKPENILV 229
Query: 499 DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL-----KGVPYRPQDSDV 335
D +IKL DFG A K + ++ G+ Y +PE+L G D D
Sbjct: 230 DRTGHIKLVDFGSA---AKMNSNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDW 286
Query: 334 WSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN---KVSFPREPKVSAECRKLITRILAPLK 164
WS+GV+ Y ++YGR PF + + + N + FP +PKVS++ LI +L K
Sbjct: 287 WSVGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQK 346
Query: 163 MRVKIPQILADPWLN 119
R+K + P+ +
Sbjct: 347 ERLKFEGLCCHPFFS 361
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 102 bits (245), Expect = 1e-21
Identities = 63/189 (33%), Positives = 100/189 (52%), Gaps = 4/189 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHI--DETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL 503
++IVMEY + G L+ I + + + E + WF Q+ + + H+R ++HRDIK +N+
Sbjct: 76 LFIVMEYCDGGDLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKILHRDIKAQNIF 135
Query: 502 MD-HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
+ +G+ KL DFG AR N L+ T G+ Y SPEI + PY + +D+WS+
Sbjct: 136 LSKNGMVAKLGDFGIAR----VLNNSMELARTCIGTPYYLSPEICQNKPYNNK-TDIWSL 190
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL-APLKMRVKI 149
G VLY + + PF+ N QL+ ++ P P S E LI+++ + R I
Sbjct: 191 GCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSRELHSLISQLFQVSPRDRPSI 250
Query: 148 PQILADPWL 122
IL P+L
Sbjct: 251 NSILKRPFL 259
>X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon
protein.
Length = 737
Score = 102 bits (244), Expect = 2e-21
Identities = 53/154 (34%), Positives = 92/154 (59%), Gaps = 1/154 (0%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K ++ VMEY G L+ I++ + DE R R + ++ A+ + H+ GV++RD+K +N+
Sbjct: 479 KDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNI 538
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D + KL+DFG + + NGV + TFCG+ Y +PEIL+ + Y P D W++
Sbjct: 539 LLDAEGHCKLADFGMCKEGI--LNGV--TTTTFCGTPDYIAPEILQELEYGP-SVDWWAL 593
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
GV++Y ++ G+ PF+ N L + + + V +P
Sbjct: 594 GVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP 627
>BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 102 bits (244), Expect = 2e-21
Identities = 53/154 (34%), Positives = 92/154 (59%), Gaps = 1/154 (0%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K ++ VMEY G L+ I++ + DE R R + ++ A+ + H+ GV++RD+K +N+
Sbjct: 479 KDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNI 538
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D + KL+DFG + + NGV + TFCG+ Y +PEIL+ + Y P D W++
Sbjct: 539 LLDAEGHCKLADFGMCKEGI--LNGV--TTTTFCGTPDYIAPEILQELEYGP-SVDWWAL 593
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
GV++Y ++ G+ PF+ N L + + + V +P
Sbjct: 594 GVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP 627
>BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 102 bits (244), Expect = 2e-21
Identities = 53/154 (34%), Positives = 92/154 (59%), Gaps = 1/154 (0%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENL 506
K ++ VMEY G L+ I++ + DE R R + ++ A+ + H+ GV++RD+K +N+
Sbjct: 479 KDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNI 538
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+D + KL+DFG + + NGV + TFCG+ Y +PEIL+ + Y P D W++
Sbjct: 539 LLDAEGHCKLADFGMCKEGI--LNGV--TTTTFCGTPDYIAPEILQELEYGP-SVDWWAL 593
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
GV++Y ++ G+ PF+ N L + + + V +P
Sbjct: 594 GVLMYEMMAGQPPFEADNEDDLFESILHDDVLYP 627
>BC040457-1|AAH40457.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II alpha protein.
Length = 478
Score = 102 bits (244), Expect = 2e-21
Identities = 65/193 (33%), Positives = 102/193 (52%), Gaps = 8/193 (4%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD- 497
Y++ + G L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+
Sbjct: 86 YLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLAS 145
Query: 496 --HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 323
G +KL+DFG A + F F G+ Y SPE+L+ PY + D+W+ G
Sbjct: 146 KLKGAAVKLADFGLAIEVEGEQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDLWACG 200
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMR 158
V+LY ++ G PF D + +L KQ++ FP V+ E + LI ++L P K R
Sbjct: 201 VILYILLVGYPPFWDEDQHRLYKQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK-R 259
Query: 157 VKIPQILADPWLN 119
+ + L PW++
Sbjct: 260 ITAAEALKHPWIS 272
>U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kinase
homolog protein.
Length = 174
Score = 101 bits (243), Expect = 2e-21
Identities = 49/115 (42%), Positives = 70/115 (60%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+++VMEY G L D I K+ +DE RR F+Q++ VDYCH VVHRD+K EN+L+D
Sbjct: 65 IFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD 124
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVW 332
+N K++DFG + +G F T CGS YA+PE++ G Y + D+W
Sbjct: 125 AHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYVGPEVDLW 174
>BC032784-1|AAH32784.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II delta protein.
Length = 478
Score = 101 bits (243), Expect = 2e-21
Identities = 64/200 (32%), Positives = 105/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++E+V++CH G+VHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLK 138
Query: 517 CENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ PY +
Sbjct: 139 PENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKDPY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITASEALKHPWI 272
>AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional
calcium/calmodulin-dependent protein kinase II delta2
isoform protein.
Length = 499
Score = 101 bits (243), Expect = 2e-21
Identities = 64/200 (32%), Positives = 105/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++E+V++CH G+VHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLK 138
Query: 517 CENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ PY +
Sbjct: 139 PENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKDPY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITASEALKHPWI 272
>AB209288-1|BAD92525.1| 522|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
isoform 1 variant protein.
Length = 522
Score = 101 bits (243), Expect = 2e-21
Identities = 64/200 (32%), Positives = 105/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++E+V++CH G+VHRD+K
Sbjct: 109 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLK 168
Query: 517 CENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ PY +
Sbjct: 169 PENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKDPY-GK 223
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 224 PVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 283
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 284 TINPAK-RITASEALKHPWI 302
>AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 4 isoform b variant protein.
Length = 765
Score = 101 bits (242), Expect = 3e-21
Identities = 68/204 (33%), Positives = 113/204 (55%), Gaps = 16/204 (7%)
Frame = -2
Query: 685 KPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHER-GVVHRDIKCEN 509
+P Y+V+E G LL+ IRK +H E+ + + LV AV + HE GVVHRD+K EN
Sbjct: 469 QPHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPEN 528
Query: 508 LLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSD 338
+L G +K+ DFGFAR ++P++ + +T C + YA+PE+L Y + D
Sbjct: 529 ILYADDTPGAPVKIIDFGFAR--LRPQSPGVPM-QTPCFTLQYAAPELLAQQGY-DESCD 584
Query: 337 VWSMGVVLYAIVYGRLPFD-------DTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLI 188
+WS+GV+LY ++ G++PF + +++ ++ + + S E VS E ++L+
Sbjct: 585 LWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELV 644
Query: 187 TRILA--PLKMRVKIPQILADPWL 122
+L P K R+K+ + WL
Sbjct: 645 RGLLTVDPAK-RLKLEGLRGSSWL 667
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/171 (26%), Positives = 94/171 (54%), Gaps = 4/171 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++++++Y G + + + Q+ E R + ++V A+++ H+ G+++RD+K EN+L+D
Sbjct: 111 LHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLD 170
Query: 496 HGLNIKLSDFGFARGHM-KPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 320
+I L+DFG ++ + + K F +FCG+ Y +PEI++ + D WS+G+
Sbjct: 171 SEGHIVLTDFGLSKEFLTEEKERTF----SFCGTIEYMAPEIIRSKTGHGKAVDWWSLGI 226
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSAECRKLITRIL 176
+L+ ++ G PF +V ++ S P P++ + L+ R+L
Sbjct: 227 LLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLL 277
>AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein.
Length = 347
Score = 101 bits (242), Expect = 3e-21
Identities = 61/206 (29%), Positives = 108/206 (52%), Gaps = 4/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRG---RRWFKQLVEAVDYCHERGVVHRDIKCENL 506
+Y+++EYA G L + K DE R RR ++L +A+ YCH + V+HRDIK ENL
Sbjct: 150 IYLILEYAPRGMLYKELHKTCTFDEQRTATVRRIMEELADALMYCHGKKVIHRDIKPENL 209
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+ +K++DFG++ + +T CG+ Y PE+++G + + D+W +
Sbjct: 210 LLGLKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCI 262
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKI 149
GV+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+ +
Sbjct: 263 GVLCYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPL 321
Query: 148 PQILADPWLNPNQQSKHDETDLQEHA 71
Q+ A PW+ N + + LQ A
Sbjct: 322 AQVSAHPWVRANSRRVLPPSALQSVA 347
>AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein.
Length = 258
Score = 101 bits (242), Expect = 3e-21
Identities = 52/151 (34%), Positives = 91/151 (60%), Gaps = 1/151 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++ VMEY G L+ I++ + DE R R + ++ A+ + H+ GV++RD+K +N+L+D
Sbjct: 3 LFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLD 62
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+ KL+DFG + + NGV + TFCG+ Y +PEIL+ + Y P D W++GV+
Sbjct: 63 AEGHCKLADFGMCKEGI--LNGV--TTTTFCGTPDYIAPEILQELEYGP-SVDWWALGVL 117
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
+Y ++ G+ PF+ N L + + + V +P
Sbjct: 118 MYEMMAGQPPFEADNEDDLFESILHDDVLYP 148
>BC031647-1|AAH31647.1| 520|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 1,
alpha protein.
Length = 520
Score = 101 bits (241), Expect = 4e-21
Identities = 61/213 (28%), Positives = 113/213 (53%), Gaps = 5/213 (2%)
Frame = -2
Query: 667 VMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGL 488
V + G ++++ D+ E + R + + ++ ++Y H + +VHRDIK NLL+
Sbjct: 267 VFDLLRKGPVMEV-PCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDG 325
Query: 487 NIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL--KGVPYRPQDSDVWSMGVVL 314
++K++DFG + G A + G+ A+ +PE + G + + DVW+ GV L
Sbjct: 326 HVKIADFGVSNQF----EGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTL 381
Query: 313 YAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKIPQI 140
Y VYG+ PF D L ++++N+ V FP P++S E + LI ++L + R+ +P I
Sbjct: 382 YCFVYGKCPFIDDFILALHRKIKNEPVVFPEGPEISEELKDLILKMLDKNPETRIGVPDI 441
Query: 139 LADPWLNPN-QQSKHDETDLQEHAKTSKEEIKS 44
PW+ N ++ E + + ++EE+K+
Sbjct: 442 KLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKN 474
>AY987011-1|AAX88806.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
protein.
Length = 489
Score = 101 bits (241), Expect = 4e-21
Identities = 64/199 (32%), Positives = 104/199 (52%), Gaps = 8/199 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++E+V++CH G+VHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLK 138
Query: 517 CENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ PY +
Sbjct: 139 PENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKDPY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKML 253
Query: 175 A--PLKMRVKIPQILADPW 125
P K R+ + L PW
Sbjct: 254 TINPAK-RITASEALKHPW 271
>AF145711-1|AAD30559.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha-B
subunit protein.
Length = 489
Score = 100 bits (240), Expect = 5e-21
Identities = 64/193 (33%), Positives = 102/193 (52%), Gaps = 8/193 (4%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD- 497
Y++ + G L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+
Sbjct: 86 YLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLAS 145
Query: 496 --HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 323
G +KL+DFG A + F F G+ Y SPE+L+ PY + D+W+ G
Sbjct: 146 KLKGAAVKLADFGLAIEVEGEQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDLWACG 200
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMR 158
V+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L P K R
Sbjct: 201 VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK-R 259
Query: 157 VKIPQILADPWLN 119
+ + L PW++
Sbjct: 260 ITAAEALKHPWIS 272
>AF145710-1|AAD30558.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha
subunit protein.
Length = 478
Score = 100 bits (240), Expect = 5e-21
Identities = 64/193 (33%), Positives = 102/193 (52%), Gaps = 8/193 (4%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD- 497
Y++ + G L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+
Sbjct: 86 YLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLAS 145
Query: 496 --HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 323
G +KL+DFG A + F F G+ Y SPE+L+ PY + D+W+ G
Sbjct: 146 KLKGAAVKLADFGLAIEVEGEQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDLWACG 200
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMR 158
V+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L P K R
Sbjct: 201 VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK-R 259
Query: 157 VKIPQILADPWLN 119
+ + L PW++
Sbjct: 260 ITAAEALKHPWIS 272
>AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent
protein kinase II alpha protein.
Length = 478
Score = 100 bits (240), Expect = 5e-21
Identities = 64/193 (33%), Positives = 102/193 (52%), Gaps = 8/193 (4%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD- 497
Y++ + G L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+
Sbjct: 86 YLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLAS 145
Query: 496 --HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 323
G +KL+DFG A + F F G+ Y SPE+L+ PY + D+W+ G
Sbjct: 146 KLKGAAVKLADFGLAIEVEGEQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDLWACG 200
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMR 158
V+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L P K R
Sbjct: 201 VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK-R 259
Query: 157 VKIPQILADPWLN 119
+ + L PW++
Sbjct: 260 ITAAEALKHPWIS 272
>AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein.
Length = 527
Score = 100 bits (240), Expect = 5e-21
Identities = 64/193 (33%), Positives = 102/193 (52%), Gaps = 8/193 (4%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD- 497
Y++ + G L + I ++ E +Q++EAV +CH+ GVVHRD+K ENLL+
Sbjct: 135 YLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLAS 194
Query: 496 --HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMG 323
G +KL+DFG A + F F G+ Y SPE+L+ PY + D+W+ G
Sbjct: 195 KLKGAAVKLADFGLAIEVEGEQQAWFG----FAGTPGYLSPEVLRKDPY-GKPVDLWACG 249
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRILA--PLKMR 158
V+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L P K R
Sbjct: 250 VILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSK-R 308
Query: 157 VKIPQILADPWLN 119
+ + L PW++
Sbjct: 309 ITAAEALKHPWIS 321
>X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha
mRNA for protein kinase C alpha. ).
Length = 672
Score = 99 bits (238), Expect = 8e-21
Identities = 54/168 (32%), Positives = 99/168 (58%), Gaps = 3/168 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y VMEY G L+ I++ E + + ++ + + H+RG+++RD+K +N+++D
Sbjct: 413 LYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLD 472
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+IK++DFG + HM +GV + TFCG+ Y +PEI+ PY + D W+ GV+
Sbjct: 473 SEGHIKIADFGMCKEHM--MDGV--TTRTFCGTPDYIAPEIIAYQPY-GKSVDWWAYGVL 527
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAE--CRKLITR 182
LY ++ G+ PFD + +L + + ++ VS+P+ A C+ L+T+
Sbjct: 528 LYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTK 575
>BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 99 bits (238), Expect = 8e-21
Identities = 54/168 (32%), Positives = 99/168 (58%), Gaps = 3/168 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y VMEY G L+ I++ E + + ++ + + H+RG+++RD+K +N+++D
Sbjct: 413 LYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLD 472
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+IK++DFG + HM +GV + TFCG+ Y +PEI+ PY + D W+ GV+
Sbjct: 473 SEGHIKIADFGMCKEHM--MDGV--TTRTFCGTPDYIAPEIIAYQPY-GKSVDWWAYGVL 527
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAE--CRKLITR 182
LY ++ G+ PFD + +L + + ++ VS+P+ A C+ L+T+
Sbjct: 528 LYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTK 575
>BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 99 bits (238), Expect = 8e-21
Identities = 54/168 (32%), Positives = 99/168 (58%), Gaps = 3/168 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y VMEY G L+ I++ E + + ++ + + H+RG+++RD+K +N+++D
Sbjct: 413 LYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLD 472
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+IK++DFG + HM +GV + TFCG+ Y +PEI+ PY + D W+ GV+
Sbjct: 473 SEGHIKIADFGMCKEHM--MDGV--TTRTFCGTPDYIAPEIIAYQPY-GKSVDWWAYGVL 527
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAE--CRKLITR 182
LY ++ G+ PFD + +L + + ++ VS+P+ A C+ L+T+
Sbjct: 528 LYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTK 575
>AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6
protein protein.
Length = 672
Score = 99 bits (238), Expect = 8e-21
Identities = 53/168 (31%), Positives = 100/168 (59%), Gaps = 3/168 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y VMEY G L+ I++ E + + ++ + + H+RG+++RD+K +N+++D
Sbjct: 413 LYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLD 472
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+IK++DFG + HM +GV + TFCG+ Y +PEI+ PY + D W+ GV+
Sbjct: 473 SEGHIKIADFGMCKEHM--MDGV--TTRTFCGTPDYIAPEIIAYQPY-GKSVDWWAYGVL 527
Query: 316 LYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR--EPKVSAECRKLITR 182
LY ++ G+ PFD + +L + + ++ VS+P+ + + C+ L+T+
Sbjct: 528 LYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSVCKGLMTK 575
>AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase
protein.
Length = 347
Score = 99 bits (238), Expect = 8e-21
Identities = 60/206 (29%), Positives = 108/206 (52%), Gaps = 4/206 (1%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRG---RRWFKQLVEAVDYCHERGVVHRDIKCENL 506
+Y+++EYA G L ++K DE R R ++L +A+ YCH + V+HRDIK ENL
Sbjct: 150 IYLILEYAPRGMLYKELQKSCTFDEQRTATVRAVMEELADALMYCHGKKVIHRDIKPENL 209
Query: 505 LMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
L+ +K++DFG++ + +T CG+ Y PE+++G + + D+W +
Sbjct: 210 LLGLKGELKIADFGWS------VHAPSLRRKTMCGTLDYLPPEMIEGRMHN-EKVDLWCI 262
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKI 149
GV+ Y ++ G PF+ ++ + +++ KV V + LI+++L R+ +
Sbjct: 263 GVLCYELLVGNPPFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPL 321
Query: 148 PQILADPWLNPNQQSKHDETDLQEHA 71
Q+ A PW+ N + + LQ A
Sbjct: 322 AQVSAHPWVRANSRRVLPPSALQSVA 347
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 99 bits (238), Expect = 8e-21
Identities = 59/203 (29%), Positives = 106/203 (52%), Gaps = 1/203 (0%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+++EYA G L ++K DE R ++L +A+ YCH + V+HRDIK ENLL+
Sbjct: 150 IYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLG 209
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+K++DFG++ + +T CG+ Y PE+++G + D+W +GV+
Sbjct: 210 LKGELKIADFGWS------VHATSLRRKTMCGTLDYLPPEMIEG-RIDNEKVDLWCIGVL 262
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
Y ++ G PF+ ++ + +++ KV V + LI+++L R+ + Q+
Sbjct: 263 CYELLVGN-PFESASHNETYRRIV-KVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQV 320
Query: 139 LADPWLNPNQQSKHDETDLQEHA 71
A PW+ N + + LQ A
Sbjct: 321 SAHPWVRANSRRVLPPSALQSVA 343
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 99.5 bits (237), Expect = 1e-20
Identities = 61/197 (30%), Positives = 100/197 (50%), Gaps = 5/197 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
VY+V+E NG + ++ + + E R + Q++ + Y H G++HRD+ NLL+
Sbjct: 85 VYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLL 144
Query: 499 DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 320
+NIK++DFG A P + T CG+ Y SPEI + +SDVWS+G
Sbjct: 145 TRNMNIKIADFGLATQLKMPHEKHY----TLCGTPNYISPEIATRSAH-GLESDVWSLGC 199
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSAECRKLITRILAPLKM-RVK 152
+ Y ++ GR PFD T +K NKV + +S E + LI ++L R+
Sbjct: 200 MFYTLLIGRPPFD----TDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLRRNPADRLS 255
Query: 151 IPQILADPWLNPNQQSK 101
+ +L P+++ N +K
Sbjct: 256 LSSVLDHPFMSRNSSTK 272
>U23460-1|AAC99802.1| 664|Homo sapiens proline rich
calmodulin-dependent protein kinase protein.
Length = 664
Score = 99.5 bits (237), Expect = 1e-20
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ Y +
Sbjct: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITAHEALKHPWV 272
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 99.5 bits (237), Expect = 1e-20
Identities = 61/197 (30%), Positives = 100/197 (50%), Gaps = 5/197 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
VY+V+E NG + ++ + + E R + Q++ + Y H G++HRD+ NLL+
Sbjct: 85 VYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLL 144
Query: 499 DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 320
+NIK++DFG A P + T CG+ Y SPEI + +SDVWS+G
Sbjct: 145 TRNMNIKIADFGLATQLKMPHEKHY----TLCGTPNYISPEIATRSAH-GLESDVWSLGC 199
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSAECRKLITRILAPLKM-RVK 152
+ Y ++ GR PFD T +K NKV + +S E + LI ++L R+
Sbjct: 200 MFYTLLIGRPPFD----TDTVKNTLNKVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLS 255
Query: 151 IPQILADPWLNPNQQSK 101
+ +L P+++ N +K
Sbjct: 256 LSSVLDHPFMSRNSSTK 272
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 99.5 bits (237), Expect = 1e-20
Identities = 54/167 (32%), Positives = 96/167 (57%), Gaps = 10/167 (5%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++ V+EY G L+ +++ + + E R + ++ A++Y HERG+++RD+K +N+L+D
Sbjct: 319 LFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLD 378
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+IKL+D+G + ++P + + TFCG+ Y +PEIL+G Y D W++GV+
Sbjct: 379 SEGHIKLTDYGMCKEGLRPGD----TTSTFCGTPNYIAPEILRGEDY-GFSVDWWALGVL 433
Query: 316 LYAIVYGRLPFD--------DTNYTQLLKQV--QNKVSFPREPKVSA 206
++ ++ GR PFD D N L QV + ++ PR V A
Sbjct: 434 MFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSMSVKA 480
>BC019070-1|AAH19070.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II beta protein.
Length = 503
Score = 99.5 bits (237), Expect = 1e-20
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ Y +
Sbjct: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITAHEALKHPWV 272
>AK222703-1|BAD96423.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase IIB isoform
2 variant protein.
Length = 542
Score = 99.5 bits (237), Expect = 1e-20
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ Y +
Sbjct: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITAHEALKHPWV 272
>AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 4 protein.
Length = 518
Score = 99.5 bits (237), Expect = 1e-20
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ Y +
Sbjct: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITAHEALKHPWV 272
>AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 2 protein.
Length = 479
Score = 99.5 bits (237), Expect = 1e-20
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ Y +
Sbjct: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITAHEALKHPWV 272
>AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 1 protein.
Length = 503
Score = 99.5 bits (237), Expect = 1e-20
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ Y +
Sbjct: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITAHEALKHPWV 272
>AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinase B
(RSK-B) protein.
Length = 772
Score = 99.5 bits (237), Expect = 1e-20
Identities = 67/200 (33%), Positives = 111/200 (55%), Gaps = 16/200 (8%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHER-GVVHRDIKCENLLM- 500
Y+V+E G LL+ IRK +H E+ + + LV AV + HE GVVHRD+K EN+L
Sbjct: 480 YLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYA 539
Query: 499 --DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
G +K+ DFGFAR ++P++ + +T C + YA+PE+L Y + D+WS+
Sbjct: 540 DDTPGAPVKIIDFGFAR--LRPQSPGVPM-QTPCFTLQYAAPELLAQQGY-DESCDLWSL 595
Query: 325 GVVLYAIVYGRLPFD-------DTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITRIL 176
GV+LY ++ G++PF + +++ ++ + + S E VS E ++L+ +L
Sbjct: 596 GVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLL 655
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+K+ + WL
Sbjct: 656 TVDPAK-RLKLEGLRGSSWL 674
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/171 (26%), Positives = 94/171 (54%), Gaps = 4/171 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++++++Y G + + + Q+ E R + ++V A+++ H+ G+++RD+K EN+L+D
Sbjct: 111 LHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLD 170
Query: 496 HGLNIKLSDFGFARGHM-KPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 320
+I L+DFG ++ + + K F +FCG+ Y +PEI++ + D WS+G+
Sbjct: 171 SEGHIVLTDFGLSKEFLTEEKERTF----SFCGTIEYMAPEIIRSKTGHGKAVDWWSLGI 226
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSAECRKLITRIL 176
+L+ ++ G PF +V ++ S P P++ + L+ R+L
Sbjct: 227 LLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLL 277
>AF140350-1|AAD42070.1| 449|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 7
subunit protein.
Length = 449
Score = 99.5 bits (237), Expect = 1e-20
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ Y +
Sbjct: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITAHEALKHPWV 272
>AF083419-1|AAD42038.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e
subunit protein.
Length = 517
Score = 99.5 bits (237), Expect = 1e-20
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ Y +
Sbjct: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITAHEALKHPWV 272
>AF081924-1|AAD42037.1| 492|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 6
subunit protein.
Length = 492
Score = 99.5 bits (237), Expect = 1e-20
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ Y +
Sbjct: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITAHEALKHPWV 272
>AF081572-1|AAD42036.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e'
subunit protein.
Length = 503
Score = 99.5 bits (237), Expect = 1e-20
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ Y +
Sbjct: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITAHEALKHPWV 272
>AF078803-1|AAD42035.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 99.5 bits (237), Expect = 1e-20
Identities = 65/200 (32%), Positives = 104/200 (52%), Gaps = 8/200 (4%)
Frame = -2
Query: 697 SVNFKPLVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIK 518
S++ + Y+V + G L + I ++ E +Q++EAV +CH+ GVVHRD+K
Sbjct: 79 SISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLK 138
Query: 517 CENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQ 347
ENLL+ G +KL+DFG A + F F G+ Y SPE+L+ Y +
Sbjct: 139 PENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKEAY-GK 193
Query: 346 DSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKLITRIL 176
D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + LI ++L
Sbjct: 194 PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML 253
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+ + L PW+
Sbjct: 254 TINPAK-RITAHEALKHPWV 272
>AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and
stress-activated protein kinase-2 protein.
Length = 705
Score = 99.5 bits (237), Expect = 1e-20
Identities = 67/200 (33%), Positives = 111/200 (55%), Gaps = 16/200 (8%)
Frame = -2
Query: 673 YIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHER-GVVHRDIKCENLLM- 500
Y+V+E G LL+ IRK +H E+ + + LV AV + HE GVVHRD+K EN+L
Sbjct: 458 YLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYA 517
Query: 499 --DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
G +K+ DFGFAR ++P++ + +T C + YA+PE+L Y + D+WS+
Sbjct: 518 DDTPGAPVKIIDFGFAR--LRPQSPGVPM-QTPCFTLQYAAPELLAQQGY-DESCDLWSL 573
Query: 325 GVVLYAIVYGRLPFD-------DTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITRIL 176
GV+LY ++ G++PF + +++ ++ + + S E VS E ++L+ +L
Sbjct: 574 GVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLL 633
Query: 175 A--PLKMRVKIPQILADPWL 122
P K R+K+ + WL
Sbjct: 634 TVDPAK-RLKLEGLRGSSWL 652
Score = 87.4 bits (207), Expect = 5e-17
Identities = 45/171 (26%), Positives = 94/171 (54%), Gaps = 4/171 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++++++Y G + + + Q+ E R + ++V A+++ H+ G+++RD+K EN+L+D
Sbjct: 95 LHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLD 154
Query: 496 HGLNIKLSDFGFARGHM-KPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 320
+I L+DFG ++ + + K F +FCG+ Y +PEI++ + D WS+G+
Sbjct: 155 SEGHIVLTDFGLSKEFLTEEKERTF----SFCGTIEYMAPEIIRSKTGHGKAVDWWSLGI 210
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSAECRKLITRIL 176
+L+ ++ G PF +V ++ S P P++ + L+ R+L
Sbjct: 211 LLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLL 261
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 99.5 bits (237), Expect = 1e-20
Identities = 61/197 (30%), Positives = 100/197 (50%), Gaps = 5/197 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIR-KDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLM 500
VY+V+E NG + ++ + + E R + Q++ + Y H G++HRD+ NLL+
Sbjct: 85 VYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLL 144
Query: 499 DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGV 320
+NIK++DFG A P + T CG+ Y SPEI + +SDVWS+G
Sbjct: 145 TRNMNIKIADFGLATQLKMPHEKHY----TLCGTPNYISPEIATRSAH-GLESDVWSLGC 199
Query: 319 VLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSAECRKLITRILAPLKM-RVK 152
+ Y ++ GR PFD T +K NKV + +S E + LI ++L R+
Sbjct: 200 MFYTLLIGRPPFD----TDTVKNTLNKVVLADYEMPTFLSIEAKDLIHQLLRRNPADRLS 255
Query: 151 IPQILADPWLNPNQQSK 101
+ +L P+++ N +K
Sbjct: 256 LSSVLDHPFMSRNSSTK 272
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 99.1 bits (236), Expect = 1e-20
Identities = 54/167 (32%), Positives = 96/167 (57%), Gaps = 10/167 (5%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++ V+EY G L+ +++ + + E R + ++ A++Y HERG+++RD+K +N+L+D
Sbjct: 319 LFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLD 378
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+IKL+D+G + ++P + + TFCG+ Y +PEIL+G Y D W++GV+
Sbjct: 379 SEGHIKLTDYGMCKEGLRPGD----TTSTFCGTPNYIAPEILRGEDY-GFSVDWWALGVL 433
Query: 316 LYAIVYGRLPFD--------DTNYTQLLKQV--QNKVSFPREPKVSA 206
++ ++ GR PFD D N L QV + ++ PR V A
Sbjct: 434 MFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKA 480
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 99.1 bits (236), Expect = 1e-20
Identities = 54/167 (32%), Positives = 96/167 (57%), Gaps = 10/167 (5%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
++ V+EY G L+ +++ + + E R + ++ A++Y HERG+++RD+K +N+L+D
Sbjct: 319 LFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLD 378
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+IKL+D+G + ++P + + TFCG+ Y +PEIL+G Y D W++GV+
Sbjct: 379 SEGHIKLTDYGMCKEGLRPGD----TTSTFCGTPNYIAPEILRGEDY-GFSVDWWALGVL 433
Query: 316 LYAIVYGRLPFD--------DTNYTQLLKQV--QNKVSFPREPKVSA 206
++ ++ GR PFD D N L QV + ++ PR V A
Sbjct: 434 MFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKA 480
>AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 498
Score = 98.7 bits (235), Expect = 2e-20
Identities = 56/183 (30%), Positives = 103/183 (56%), Gaps = 4/183 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQI 140
P+I
Sbjct: 438 PEI 440
>AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 545
Score = 98.7 bits (235), Expect = 2e-20
Identities = 56/183 (30%), Positives = 103/183 (56%), Gaps = 4/183 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQI 140
P+I
Sbjct: 438 PEI 440
>AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform
protein.
Length = 490
Score = 98.7 bits (235), Expect = 2e-20
Identities = 56/183 (30%), Positives = 103/183 (56%), Gaps = 4/183 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQI 140
P+I
Sbjct: 438 PEI 440
>AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta-3x protein.
Length = 498
Score = 98.7 bits (235), Expect = 2e-20
Identities = 56/183 (30%), Positives = 103/183 (56%), Gaps = 4/183 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 263 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 321
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVP--YRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 322 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMG 377
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 378 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 437
Query: 148 PQI 140
P+I
Sbjct: 438 PEI 440
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 98.3 bits (234), Expect = 3e-20
Identities = 51/167 (30%), Positives = 91/167 (54%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y V++Y G L +++++ E R R + ++ A+ Y H +V+RD+K EN+L+D
Sbjct: 267 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD 326
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+I L+DFG + +++ + + TFCG+ Y +PE+L PY + D W +G V
Sbjct: 327 SQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPEVLHKQPY-DRTVDWWCLGAV 381
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
LY ++YG PF N ++ + NK +P ++ R L+ +L
Sbjct: 382 LYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSARHLLEGLL 427
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 98.3 bits (234), Expect = 3e-20
Identities = 51/167 (30%), Positives = 91/167 (54%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y V++Y G L +++++ E R R + ++ A+ Y H +V+RD+K EN+L+D
Sbjct: 172 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD 231
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+I L+DFG + +++ + + TFCG+ Y +PE+L PY + D W +G V
Sbjct: 232 SQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPEVLHKQPY-DRTVDWWCLGAV 286
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
LY ++YG PF N ++ + NK +P ++ R L+ +L
Sbjct: 287 LYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSARHLLEGLL 332
>CR536608-1|CAO03523.1| 326|Homo sapiens pim-3 oncogene protein.
Length = 326
Score = 98.3 bits (234), Expect = 3e-20
Identities = 70/186 (37%), Positives = 105/186 (56%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 IVMEYAENGS-LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD- 497
+V+E E L D I + +DE RR+F Q++ AV +CH GVVHRDIK ENLL+D
Sbjct: 121 LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL 180
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+KL DFG G + K+ V+ F G+ Y+ PE ++ Y + + VWS+GV+
Sbjct: 181 RSGELKLIDFG--SGALL-KDTVYT---DFDGTRVYSPPEWIRYHRYHGRSATVWSLGVL 234
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
LY +V G +PF+ ++L+ ++ F R +VS EC++LI L+ R + QI
Sbjct: 235 LYDMVCGDIPFEQDE--EILR---GRLLFRR--RVSPECQQLIRWCLSLRPSERPSLDQI 287
Query: 139 LADPWL 122
A PW+
Sbjct: 288 AAHPWM 293
>BX539320-1|CAO03581.1| 326|Homo sapiens pim-3 oncogene protein.
Length = 326
Score = 98.3 bits (234), Expect = 3e-20
Identities = 70/186 (37%), Positives = 105/186 (56%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 IVMEYAENGS-LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD- 497
+V+E E L D I + +DE RR+F Q++ AV +CH GVVHRDIK ENLL+D
Sbjct: 121 LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL 180
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+KL DFG G + K+ V+ F G+ Y+ PE ++ Y + + VWS+GV+
Sbjct: 181 RSGELKLIDFG--SGALL-KDTVYT---DFDGTRVYSPPEWIRYHRYHGRSATVWSLGVL 234
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
LY +V G +PF+ ++L+ ++ F R +VS EC++LI L+ R + QI
Sbjct: 235 LYDMVCGDIPFEQDE--EILR---GRLLFRR--RVSPECQQLIRWCLSLRPSERPSLDQI 287
Query: 139 LADPWL 122
A PW+
Sbjct: 288 AAHPWM 293
>BC141855-1|AAI41856.1| 326|Homo sapiens pim-3 oncogene protein.
Length = 326
Score = 98.3 bits (234), Expect = 3e-20
Identities = 70/186 (37%), Positives = 105/186 (56%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 IVMEYAENGS-LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD- 497
+V+E E L D I + +DE RR+F Q++ AV +CH GVVHRDIK ENLL+D
Sbjct: 121 LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL 180
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+KL DFG G + K+ V+ F G+ Y+ PE ++ Y + + VWS+GV+
Sbjct: 181 RSGELKLIDFG--SGALL-KDTVYT---DFDGTRVYSPPEWIRYHRYHGRSATVWSLGVL 234
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
LY +V G +PF+ ++L+ ++ F R +VS EC++LI L+ R + QI
Sbjct: 235 LYDMVCGDIPFEQDE--EILR---GRLLFRR--RVSPECQQLIRWCLSLRPSERPSLDQI 287
Query: 139 LADPWL 122
A PW+
Sbjct: 288 AAHPWM 293
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 98.3 bits (234), Expect = 3e-20
Identities = 51/167 (30%), Positives = 91/167 (54%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y V++Y G L +++++ E R R + ++ A+ Y H +V+RD+K EN+L+D
Sbjct: 172 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD 231
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+I L+DFG + +++ + + TFCG+ Y +PE+L PY + D W +G V
Sbjct: 232 SQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPEVLHKQPY-DRTVDWWCLGAV 286
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
LY ++YG PF N ++ + NK +P ++ R L+ +L
Sbjct: 287 LYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSARHLLEGLL 332
>BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein.
Length = 266
Score = 98.3 bits (234), Expect = 3e-20
Identities = 56/183 (30%), Positives = 103/183 (56%), Gaps = 4/183 (2%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y+V E G ++++ + + E + R +F+ L++ ++Y H + ++HRDIK NLL+
Sbjct: 31 LYMVFELVNQGPVMEVPTL-KPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVG 89
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGV--PYRPQDSDVWSMG 323
+IK++DFG + G AL G+ A+ +PE L + + DVW+MG
Sbjct: 90 EDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMAPESLSETCKIFSGKALDVWAMG 145
Query: 322 VVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKVSAECRKLITRIL-APLKMRVKI 149
V LY V+G+ PF D L +++++ + FP +P ++ + + LITR+L + R+ +
Sbjct: 146 VTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVV 205
Query: 148 PQI 140
P+I
Sbjct: 206 PEI 208
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 98.3 bits (234), Expect = 3e-20
Identities = 51/167 (30%), Positives = 91/167 (54%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y V++Y G L +++++ E R R + ++ A+ Y H +V+RD+K EN+L+D
Sbjct: 267 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD 326
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+I L+DFG + +++ + + TFCG+ Y +PE+L PY + D W +G V
Sbjct: 327 SQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPEVLHKQPY-DRTVDWWCLGAV 381
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
LY ++YG PF N ++ + NK +P ++ R L+ +L
Sbjct: 382 LYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSARHLLEGLL 427
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 98.3 bits (234), Expect = 3e-20
Identities = 51/167 (30%), Positives = 91/167 (54%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y V++Y G L +++++ E R R + ++ A+ Y H +V+RD+K EN+L+D
Sbjct: 267 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD 326
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+I L+DFG + +++ + + TFCG+ Y +PE+L PY + D W +G V
Sbjct: 327 SQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPEVLHKQPY-DRTVDWWCLGAV 381
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
LY ++YG PF N ++ + NK +P ++ R L+ +L
Sbjct: 382 LYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSARHLLEGLL 427
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 98.3 bits (234), Expect = 3e-20
Identities = 51/167 (30%), Positives = 91/167 (54%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y V++Y G L +++++ E R R + ++ A+ Y H +V+RD+K EN+L+D
Sbjct: 186 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD 245
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+I L+DFG + +++ + + TFCG+ Y +PE+L PY + D W +G V
Sbjct: 246 SQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPEVLHKQPY-DRTVDWWCLGAV 300
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
LY ++YG PF N ++ + NK +P ++ R L+ +L
Sbjct: 301 LYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSARHLLEGLL 346
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 98.3 bits (234), Expect = 3e-20
Identities = 51/167 (30%), Positives = 91/167 (54%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y V++Y G L +++++ E R R + ++ A+ Y H +V+RD+K EN+L+D
Sbjct: 172 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD 231
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+I L+DFG + +++ + + TFCG+ Y +PE+L PY + D W +G V
Sbjct: 232 SQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPEVLHKQPY-DRTVDWWCLGAV 286
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
LY ++YG PF N ++ + NK +P ++ R L+ +L
Sbjct: 287 LYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSARHLLEGLL 332
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 98.3 bits (234), Expect = 3e-20
Identities = 51/167 (30%), Positives = 91/167 (54%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y V++Y G L +++++ E R R + ++ A+ Y H +V+RD+K EN+L+D
Sbjct: 162 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD 221
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+I L+DFG + +++ + + TFCG+ Y +PE+L PY + D W +G V
Sbjct: 222 SQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPEVLHKQPY-DRTVDWWCLGAV 276
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
LY ++YG PF N ++ + NK +P ++ R L+ +L
Sbjct: 277 LYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSARHLLEGLL 322
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 98.3 bits (234), Expect = 3e-20
Identities = 51/167 (30%), Positives = 91/167 (54%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y V++Y G L +++++ E R R + ++ A+ Y H +V+RD+K EN+L+D
Sbjct: 172 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD 231
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+I L+DFG + +++ + + TFCG+ Y +PE+L PY + D W +G V
Sbjct: 232 SQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPEVLHKQPY-DRTVDWWCLGAV 286
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
LY ++YG PF N ++ + NK +P ++ R L+ +L
Sbjct: 287 LYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSARHLLEGLL 332
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 98.3 bits (234), Expect = 3e-20
Identities = 51/167 (30%), Positives = 91/167 (54%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
+Y V++Y G L +++++ E R R + ++ A+ Y H +V+RD+K EN+L+D
Sbjct: 172 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD 231
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+I L+DFG + +++ + + TFCG+ Y +PE+L PY + D W +G V
Sbjct: 232 SQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPEVLHKQPY-DRTVDWWCLGAV 286
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRIL 176
LY ++YG PF N ++ + NK +P ++ R L+ +L
Sbjct: 287 LYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSARHLLEGLL 332
>AB114795-1|BAD42438.1| 326|Homo sapiens serine/threonine kinase
Pim-3 protein.
Length = 326
Score = 98.3 bits (234), Expect = 3e-20
Identities = 70/186 (37%), Positives = 105/186 (56%), Gaps = 3/186 (1%)
Frame = -2
Query: 670 IVMEYAENGS-LLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD- 497
+V+E E L D I + +DE RR+F Q++ AV +CH GVVHRDIK ENLL+D
Sbjct: 121 LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL 180
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
+KL DFG G + K+ V+ F G+ Y+ PE ++ Y + + VWS+GV+
Sbjct: 181 RSGELKLIDFG--SGALL-KDTVYT---DFDGTRVYSPPEWIRYHRYHGRSATVWSLGVL 234
Query: 316 LYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQI 140
LY +V G +PF+ ++L+ ++ F R +VS EC++LI L+ R + QI
Sbjct: 235 LYDMVCGDIPFEQDE--EILR---GRLLFRR--RVSPECQQLIRWCLSLRPSERPSLDQI 287
Query: 139 LADPWL 122
A PW+
Sbjct: 288 AAHPWM 293
>L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein.
Length = 370
Score = 97.5 bits (232), Expect = 4e-20
Identities = 61/192 (31%), Positives = 97/192 (50%), Gaps = 7/192 (3%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLL-- 503
+Y++M+ G L D I + E R Q+++AV Y H+ G+VHRD+K ENLL
Sbjct: 91 LYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYY 150
Query: 502 -MDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
+D I +SDFG ++ M+ V + T CG+ Y +PE+L PY + D WS+
Sbjct: 151 SLDEDSKIMISDFGLSK--MEDPGSVLS---TACGTPGYVAPEVLAQKPY-SKAVDCWSI 204
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFPREPKVSAECRKLITRIL-APLKMR 158
GV+ Y ++ G PF D N +L +Q+ + + P +S + I ++ + R
Sbjct: 205 GVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKR 264
Query: 157 VKIPQILADPWL 122
Q L PW+
Sbjct: 265 FTCEQALQHPWI 276
>BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 97.5 bits (232), Expect = 4e-20
Identities = 62/192 (32%), Positives = 101/192 (52%), Gaps = 7/192 (3%)
Frame = -2
Query: 676 VYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMD 497
VY+VME A G L D + E R + + + + Y H + HR++K ENLL
Sbjct: 133 VYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYY 192
Query: 496 H---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSM 326
H I ++DFG A + K+G + + +T CG+ Y +PE+L PY D+W++
Sbjct: 193 HPGEESKILITDFGLA--YSGKKSGDWTM-KTLCGTPEYIAPEVLLRKPY-TSAVDMWAL 248
Query: 325 GVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPRE--PKVSAECRKLITRIL-APLKMR 158
GV+ YA++ G LPFDD + T+L +++ + K ++ E P +S + I ++L R
Sbjct: 249 GVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHR 308
Query: 157 VKIPQILADPWL 122
+ Q L PW+
Sbjct: 309 MSAGQALDHPWV 320
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,239,188
Number of Sequences: 237096
Number of extensions: 2481227
Number of successful extensions: 11077
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 7498
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8064
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8959138240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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