Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmte12a07
(780 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 228 1e-59
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 228 1e-59
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 228 1e-59
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 224 3e-58
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 224 3e-58
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 224 3e-58
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 224 3e-58
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 223 6e-58
AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens ... 213 6e-55
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 210 6e-54
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 210 6e-54
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 210 6e-54
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 210 6e-54
BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein. 199 8e-51
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 175 1e-43
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 175 1e-43
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 175 1e-43
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 175 1e-43
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 175 1e-43
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 175 1e-43
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 174 3e-43
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 174 3e-43
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 174 3e-43
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 174 3e-43
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 174 3e-43
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 174 3e-43
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 174 3e-43
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 174 3e-43
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 174 3e-43
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 174 3e-43
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 171 2e-42
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 171 2e-42
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 171 3e-42
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 171 3e-42
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 171 3e-42
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 171 3e-42
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 171 3e-42
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 171 3e-42
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 171 3e-42
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 171 3e-42
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 170 6e-42
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 170 6e-42
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 170 6e-42
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 170 6e-42
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 170 6e-42
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 167 5e-41
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 167 5e-41
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 167 5e-41
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 161 3e-39
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 160 6e-39
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 160 6e-39
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 134 1e-38
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 156 1e-37
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 156 1e-37
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 156 1e-37
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 156 1e-37
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 156 1e-37
AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leuc... 156 1e-37
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 153 5e-37
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 153 5e-37
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 153 5e-37
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 153 5e-37
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 153 5e-37
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 153 9e-37
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 152 2e-36
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 152 2e-36
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 152 2e-36
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 152 2e-36
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 152 2e-36
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 151 2e-36
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 151 3e-36
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 151 4e-36
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 151 4e-36
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 151 4e-36
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 150 6e-36
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 149 8e-36
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 148 2e-35
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 148 2e-35
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 148 2e-35
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 148 2e-35
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 148 2e-35
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 148 2e-35
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 148 2e-35
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 148 2e-35
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 146 6e-35
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 142 1e-33
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 142 2e-33
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 142 2e-33
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 141 3e-33
AF542390-1|AAN62841.1| 258|Homo sapiens AT03158-like protein pr... 139 9e-33
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 136 8e-32
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 136 8e-32
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 136 1e-31
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 134 3e-31
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 134 3e-31
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 134 3e-31
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 134 3e-31
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 134 3e-31
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 133 8e-31
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 133 8e-31
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 133 8e-31
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 130 4e-30
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 130 4e-30
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 130 5e-30
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 130 5e-30
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 130 5e-30
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 130 5e-30
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 130 5e-30
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 130 5e-30
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 130 5e-30
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 130 5e-30
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 130 7e-30
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 129 1e-29
AB183428-1|BAF73616.1| 580|Homo sapiens maternal embryonic luec... 128 3e-29
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 125 2e-28
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 125 2e-28
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 125 2e-28
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 125 2e-28
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 125 2e-28
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 125 2e-28
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 122 1e-27
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 120 4e-27
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 120 4e-27
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 120 4e-27
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 120 4e-27
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 120 4e-27
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 120 6e-27
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 120 6e-27
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 120 6e-27
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 120 6e-27
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 120 8e-27
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 120 8e-27
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 120 8e-27
AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-depende... 120 8e-27
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 119 1e-26
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 119 1e-26
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 119 1e-26
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 118 2e-26
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 118 2e-26
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 118 2e-26
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 118 2e-26
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 118 2e-26
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 118 2e-26
BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing s... 118 3e-26
BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein. 118 3e-26
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 118 3e-26
AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein. 118 3e-26
BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-depe... 117 5e-26
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 117 5e-26
AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-depende... 117 5e-26
AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-depende... 117 5e-26
AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform pr... 117 5e-26
AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-depe... 117 5e-26
AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-depende... 117 5e-26
AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-depende... 117 5e-26
AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein. 117 5e-26
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 116 7e-26
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 116 7e-26
U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein ... 116 1e-25
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 116 1e-25
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 116 1e-25
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 116 1e-25
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 116 1e-25
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 116 1e-25
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 116 1e-25
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 116 1e-25
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 116 1e-25
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 116 1e-25
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 116 1e-25
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 115 2e-25
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 115 2e-25
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 115 2e-25
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 115 2e-25
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 115 2e-25
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 115 2e-25
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 115 2e-25
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 115 2e-25
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 114 4e-25
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 114 4e-25
BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kina... 114 4e-25
BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kina... 114 4e-25
BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light c... 114 4e-25
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 114 4e-25
AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kin... 114 4e-25
AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specifi... 114 4e-25
AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light c... 114 4e-25
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 114 4e-25
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 114 4e-25
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 114 4e-25
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 113 5e-25
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 113 5e-25
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 113 5e-25
L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin depend... 113 5e-25
L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-depend... 113 5e-25
D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent prot... 113 5e-25
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 113 5e-25
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 113 5e-25
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 113 5e-25
BC025687-1|AAH25687.1| 473|Homo sapiens calcium/calmodulin-depe... 113 5e-25
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 113 5e-25
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 113 5e-25
BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein. 113 5e-25
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 113 5e-25
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 113 5e-25
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 113 5e-25
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 113 5e-25
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 113 5e-25
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 113 5e-25
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 113 5e-25
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 113 5e-25
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 113 5e-25
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 113 5e-25
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 113 5e-25
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 113 5e-25
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 113 5e-25
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 113 5e-25
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 113 5e-25
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 113 5e-25
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 113 5e-25
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 113 5e-25
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 113 5e-25
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 113 5e-25
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 113 5e-25
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 113 5e-25
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 113 5e-25
BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein. 113 7e-25
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 113 9e-25
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 113 9e-25
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 113 9e-25
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 113 9e-25
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 113 9e-25
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 113 9e-25
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 113 9e-25
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 113 9e-25
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 113 9e-25
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 113 9e-25
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 113 9e-25
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 113 9e-25
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 113 9e-25
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 113 9e-25
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 113 9e-25
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 112 1e-24
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 112 2e-24
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 112 2e-24
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 112 2e-24
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 112 2e-24
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 112 2e-24
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 112 2e-24
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 112 2e-24
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 112 2e-24
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 111 2e-24
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 111 2e-24
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 111 2e-24
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 111 2e-24
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 111 2e-24
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 111 2e-24
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 111 4e-24
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 111 4e-24
AL713896-5|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 111 4e-24
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 111 4e-24
AL713896-3|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 111 4e-24
AL713896-2|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 111 4e-24
AL596247-5|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 111 4e-24
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 111 4e-24
AL596247-3|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 111 4e-24
AL596247-2|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 111 4e-24
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 111 4e-24
AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform pr... 111 4e-24
AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform pr... 111 4e-24
AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform pr... 111 4e-24
AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-depende... 111 4e-24
BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein. 110 5e-24
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 110 6e-24
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 110 6e-24
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 110 6e-24
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 110 6e-24
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 110 6e-24
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 110 6e-24
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 110 6e-24
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 110 6e-24
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 109 8e-24
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 109 8e-24
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 109 8e-24
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 109 8e-24
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 109 8e-24
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 109 8e-24
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 109 8e-24
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 109 8e-24
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 109 8e-24
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 109 8e-24
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 109 1e-23
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 109 1e-23
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 109 1e-23
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 109 1e-23
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 108 2e-23
D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein. 108 2e-23
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 108 2e-23
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 108 2e-23
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 108 3e-23
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 108 3e-23
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 108 3e-23
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 108 3e-23
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 108 3e-23
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 108 3e-23
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 108 3e-23
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 108 3e-23
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 108 3e-23
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 108 3e-23
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 108 3e-23
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 108 3e-23
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 108 3e-23
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 108 3e-23
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 107 4e-23
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 107 4e-23
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 107 4e-23
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 107 6e-23
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 107 6e-23
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 107 6e-23
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 107 6e-23
AJ252239-1|CAB65123.1| 243|Homo sapiens calcium/calmodulin depe... 106 8e-23
BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein. 106 1e-22
AL713896-1|CAI13787.1| 453|Homo sapiens calcium/calmodulin-depe... 106 1e-22
AL596247-1|CAI13964.1| 453|Homo sapiens calcium/calmodulin-depe... 106 1e-22
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 105 1e-22
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 105 1e-22
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 105 1e-22
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 105 2e-22
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 105 2e-22
L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-depend... 105 2e-22
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 105 2e-22
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 105 2e-22
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 105 2e-22
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 105 2e-22
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 105 2e-22
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 105 2e-22
AL117330-1|CAH73875.1| 543|Homo sapiens CHK2 checkpoint homolog... 105 2e-22
AJ131197-1|CAA10319.1| 543|Homo sapiens protein kinase protein. 105 2e-22
AF217975-1|AAG17218.1| 322|Homo sapiens unknown protein. 105 2e-22
AF174135-1|AAD48504.1| 543|Homo sapiens protein kinase CHK2 pro... 105 2e-22
AF096279-1|AAD11784.1| 543|Homo sapiens HuCds1 kinase protein. 105 2e-22
AF086904-1|AAC83693.1| 543|Homo sapiens protein kinase Chk2 pro... 105 2e-22
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 105 2e-22
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 105 2e-22
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 105 2e-22
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 105 2e-22
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 105 2e-22
AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 105 2e-22
AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 105 2e-22
AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 105 2e-22
AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 105 2e-22
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 105 2e-22
Z92542-3|CAI42485.1| 1030|Homo sapiens cyclin-dependent kinase-l... 104 3e-22
Y15057-1|CAA75342.1| 1030|Homo sapiens STK9 protein protein. 104 3e-22
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 104 3e-22
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 104 3e-22
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 104 3e-22
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 104 3e-22
AY217744-1|AAO64440.1| 1030|Homo sapiens serine/threonine kinase... 104 3e-22
AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting ... 104 3e-22
AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein pr... 104 3e-22
AL109798-1|CAI41159.1| 1030|Homo sapiens cyclin-dependent kinase... 104 3e-22
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 104 4e-22
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 104 4e-22
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 104 4e-22
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 104 4e-22
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 104 4e-22
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 104 4e-22
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 104 4e-22
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 103 5e-22
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 103 5e-22
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 103 5e-22
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 103 5e-22
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 103 5e-22
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 103 5e-22
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 103 5e-22
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 103 5e-22
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 103 5e-22
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 103 5e-22
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 103 5e-22
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 103 5e-22
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 103 5e-22
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 103 5e-22
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 103 5e-22
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 103 5e-22
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 103 5e-22
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 103 7e-22
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 103 7e-22
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 103 7e-22
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 103 7e-22
AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein. 103 7e-22
X85337-1|CAA59685.1| 991|Homo sapiens myosin light chain kinase... 103 1e-21
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 103 1e-21
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 102 1e-21
U77735-1|AAC78506.1| 334|Homo sapiens pim-2 protooncogene homol... 102 1e-21
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 102 1e-21
CR536608-1|CAO03523.1| 326|Homo sapiens pim-3 oncogene protein. 102 1e-21
BX539320-1|CAO03581.1| 326|Homo sapiens pim-3 oncogene protein. 102 1e-21
BC141855-1|AAI41856.1| 326|Homo sapiens pim-3 oncogene protein. 102 1e-21
BC018111-1|AAH18111.1| 311|Homo sapiens pim-2 oncogene protein. 102 1e-21
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 102 1e-21
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 102 1e-21
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 102 1e-21
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 102 1e-21
AB114795-1|BAD42438.1| 326|Homo sapiens serine/threonine kinase... 102 1e-21
AB042425-1|BAA95613.1| 311|Homo sapiens pim-2 protooncogene hom... 102 1e-21
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 102 1e-21
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 101 2e-21
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 101 2e-21
BC065932-1|AAH65932.1| 214|Homo sapiens NEK2 protein protein. 101 2e-21
AJ247087-1|CAC42766.1| 795|Homo sapiens myosin light chain kina... 101 2e-21
AY355461-1|AAQ84219.1| 347|Homo sapiens MNK1-like kinase 1b pro... 101 3e-21
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 101 4e-21
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 101 4e-21
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 101 4e-21
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 101 4e-21
BC031647-1|AAH31647.1| 520|Homo sapiens calcium/calmodulin-depe... 101 4e-21
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 101 4e-21
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 101 4e-21
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 101 4e-21
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 100 5e-21
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 100 5e-21
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 100 5e-21
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 100 5e-21
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 100 5e-21
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 99 9e-21
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 99 9e-21
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 99 9e-21
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 99 9e-21
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 100 1e-20
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 100 1e-20
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 100 1e-20
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 100 1e-20
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 100 1e-20
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 100 1e-20
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 100 1e-20
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 100 1e-20
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 100 1e-20
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 100 1e-20
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 100 1e-20
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 100 1e-20
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 100 1e-20
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 100 1e-20
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 100 1e-20
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 100 1e-20
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 100 1e-20
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 100 1e-20
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 100 1e-20
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 100 1e-20
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 100 1e-20
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 100 1e-20
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 100 1e-20
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 100 1e-20
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 100 1e-20
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 100 1e-20
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 99 2e-20
BC032709-1|AAH32709.1| 344|Homo sapiens AKT2 protein protein. 99 2e-20
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 99 2e-20
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 99 2e-20
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 99 2e-20
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 99 2e-20
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 99 2e-20
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 99 2e-20
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 99 2e-20
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 99 2e-20
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 99 2e-20
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 99 2e-20
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 99 2e-20
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 99 2e-20
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 99 2e-20
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 98 3e-20
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 98 3e-20
BC132833-1|AAI32834.1| 388|Homo sapiens hypothetical protein LO... 98 3e-20
BC132831-1|AAI32832.1| 388|Homo sapiens hypothetical protein LO... 98 3e-20
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 98 3e-20
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 98 3e-20
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 98 3e-20
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 98 3e-20
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 98 3e-20
AL139092-1|CAH73662.1| 388|Homo sapiens protein ( Human DNA seq... 98 3e-20
AL138876-2|CAI12221.2| 388|Homo sapiens protein ( Human DNA seq... 98 3e-20
AC007055-5|AAD31940.1| 312|Homo sapiens protein ( Homo sapiens ... 98 3e-20
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 98 3e-20
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 98 4e-20
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 98 4e-20
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 98 4e-20
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 98 4e-20
AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens ... 98 4e-20
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 98 4e-20
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 98 4e-20
AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein. 98 4e-20
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 97 5e-20
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 97 5e-20
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 97 5e-20
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 97 5e-20
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 97 5e-20
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 97 5e-20
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 97 5e-20
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 97 5e-20
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 97 5e-20
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 228 bits (558), Expect = 1e-59
Identities = 105/224 (46%), Positives = 160/224 (71%), Gaps = 3/224 (1%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
D+L+KFLPREIE++ L H ++I+ + ET+H +VYIVME A G LL++I+ + E
Sbjct: 51 DFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHE 110
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFA 424
R+ F QL A+ YCH+ VVHRD+KC+NLL+D NIKLSDF F++ ++ +G A
Sbjct: 111 DEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMA 170
Query: 423 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK-QVQ 247
LS+TFCGS AYA+PE+L+G+PY+P+ D+WS+GV+LY +V G +P+DD+N ++L+ Q +
Sbjct: 171 LSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKE 230
Query: 246 NKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQILADPWLNP 118
++V+FPR ++ EC+ LI +L P + R+ I +IL+ W+ P
Sbjct: 231 HRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP 274
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 228 bits (558), Expect = 1e-59
Identities = 105/224 (46%), Positives = 160/224 (71%), Gaps = 3/224 (1%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
D+L+KFLPREIE++ L H ++I+ + ET+H +VYIVME A G LL++I+ + E
Sbjct: 51 DFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHE 110
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFA 424
R+ F QL A+ YCH+ VVHRD+KC+NLL+D NIKLSDF F++ ++ +G A
Sbjct: 111 DEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMA 170
Query: 423 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK-QVQ 247
LS+TFCGS AYA+PE+L+G+PY+P+ D+WS+GV+LY +V G +P+DD+N ++L+ Q +
Sbjct: 171 LSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKE 230
Query: 246 NKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQILADPWLNP 118
++V+FPR ++ EC+ LI +L P + R+ I +IL+ W+ P
Sbjct: 231 HRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP 274
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 228 bits (558), Expect = 1e-59
Identities = 105/224 (46%), Positives = 160/224 (71%), Gaps = 3/224 (1%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
D+L+KFLPREIE++ L H ++I+ + ET+H +VYIVME A G LL++I+ + E
Sbjct: 51 DFLEKFLPREIEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHE 110
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFA 424
R+ F QL A+ YCH+ VVHRD+KC+NLL+D NIKLSDF F++ ++ +G A
Sbjct: 111 DEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMA 170
Query: 423 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK-QVQ 247
LS+TFCGS AYA+PE+L+G+PY+P+ D+WS+GV+LY +V G +P+DD+N ++L+ Q +
Sbjct: 171 LSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKE 230
Query: 246 NKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQILADPWLNP 118
++V+FPR ++ EC+ LI +L P + R+ I +IL+ W+ P
Sbjct: 231 HRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP 274
>CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein.
Length = 358
Score = 224 bits (547), Expect = 3e-58
Identities = 99/224 (44%), Positives = 157/224 (70%), Gaps = 3/224 (1%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
D++++FLPRE++++ + H ++I+ + ET+ R+YI+ME G LL+ I+ + E
Sbjct: 51 DFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHE 110
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFA 424
R+ F+QL AV YCH+ +VHRD+KCENLL+D NIKLSDFGF++ ++ NG
Sbjct: 111 DVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRII 170
Query: 423 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK-QVQ 247
LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+GV+LY +V G +P+DD++ ++L+ Q +
Sbjct: 171 LSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKE 230
Query: 246 NKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQILADPWLNP 118
++V FPR ++ EC+ LI R+L P + R+ I +IL+ WL P
Sbjct: 231 HRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQP 274
>BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 224 bits (547), Expect = 3e-58
Identities = 99/224 (44%), Positives = 157/224 (70%), Gaps = 3/224 (1%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
D++++FLPRE++++ + H ++I+ + ET+ R+YI+ME G LL+ I+ + E
Sbjct: 51 DFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHE 110
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFA 424
R+ F+QL AV YCH+ +VHRD+KCENLL+D NIKLSDFGF++ ++ NG
Sbjct: 111 DVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRII 170
Query: 423 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK-QVQ 247
LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+GV+LY +V G +P+DD++ ++L+ Q +
Sbjct: 171 LSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKE 230
Query: 246 NKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQILADPWLNP 118
++V FPR ++ EC+ LI R+L P + R+ I +IL+ WL P
Sbjct: 231 HRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQP 274
>AF362953-1|AAK98531.1| 358|Homo sapiens testis specific
serine/threonine kinase 2 protein.
Length = 358
Score = 224 bits (547), Expect = 3e-58
Identities = 99/224 (44%), Positives = 157/224 (70%), Gaps = 3/224 (1%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
D++++FLPRE++++ + H ++I+ + ET+ R+YI+ME G LL+ I+ + E
Sbjct: 51 DFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHE 110
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFA 424
R+ F+QL AV YCH+ +VHRD+KCENLL+D NIKLSDFGF++ ++ NG
Sbjct: 111 DVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRII 170
Query: 423 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK-QVQ 247
LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+GV+LY +V G +P+DD++ ++L+ Q +
Sbjct: 171 LSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKE 230
Query: 246 NKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQILADPWLNP 118
++V FPR ++ EC+ LI R+L P + R+ I +IL+ WL P
Sbjct: 231 HRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQP 274
>AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 224 bits (547), Expect = 3e-58
Identities = 99/224 (44%), Positives = 157/224 (70%), Gaps = 3/224 (1%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
D++++FLPRE++++ + H ++I+ + ET+ R+YI+ME G LL+ I+ + E
Sbjct: 51 DFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHE 110
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFA 424
R+ F+QL AV YCH+ +VHRD+KCENLL+D NIKLSDFGF++ ++ NG
Sbjct: 111 DVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRII 170
Query: 423 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK-QVQ 247
LS+TFCGS AYA+PE+L+ +PY+P+ D+WS+GV+LY +V G +P+DD++ ++L+ Q +
Sbjct: 171 LSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKE 230
Query: 246 NKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQILADPWLNP 118
++V FPR ++ EC+ LI R+L P + R+ I +IL+ WL P
Sbjct: 231 HRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQP 274
>AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine
kinase 4 protein.
Length = 328
Score = 223 bits (545), Expect = 6e-58
Identities = 110/232 (47%), Positives = 151/232 (65%), Gaps = 13/232 (5%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDET 601
DYL KFLPREI+V+K L+H+ LI F +AIE+T RVYI++E A+ G +L+ I++ E
Sbjct: 64 DYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEP 123
Query: 600 RGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKN----- 436
+WF QL + Y H + +VHRD+K ENLL+D N+K+SDFGFA+ M P N
Sbjct: 124 LAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGC 181
Query: 435 -------GVFA-LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD 280
F+ LS+T+CGS+AYA PEIL+G+PY P SD WSMGV+LY +V LPFDD
Sbjct: 182 SPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDD 241
Query: 279 TNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPLKMRVKIPQILADPWL 124
TN +LL++ Q +V+FP +S EC+ LI ++L R I I+ D W+
Sbjct: 242 TNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWV 293
>AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens
cDNA FLJ29008 fis, clone TST06032. ).
Length = 338
Score = 213 bits (520), Expect = 6e-55
Identities = 111/242 (45%), Positives = 151/242 (62%), Gaps = 23/242 (9%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDET 601
DYL KFLPREI+V+K L+H+ LI F +AIE+T RVYI++E A+ G +L+ IR+ E
Sbjct: 64 DYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIRRYGACSEP 123
Query: 600 RGRRWFKQLVEAVDYCHERGVVH----------RDIKCENLLMDHGLNIKLSDFGFARGH 451
+WF QL + Y H + +VH RD+K ENLL+D N+K+SDFGFA+
Sbjct: 124 LAGKWFSQLTLGIAYLHSKSIVHRLMPSLSAAGRDLKLENLLLDKWENVKISDFGFAK-- 181
Query: 450 MKPKN------------GVFA-LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYA 310
M P N F+ LS+T+CGS+AYA PEIL+G+PY P SD WSMGV+LY
Sbjct: 182 MVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYT 241
Query: 309 IVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILAPLKMRVKIPQILADP 130
+V LPFDDTN +LL++ Q +V+FP +S EC+ LI ++L R I I+ D
Sbjct: 242 LVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDS 301
Query: 129 WL 124
W+
Sbjct: 302 WV 303
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 210 bits (512), Expect = 6e-54
Identities = 99/221 (44%), Positives = 153/221 (69%), Gaps = 2/221 (0%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
+++++FLPRE+++V+ L H+N+I+ + +E+ ++ +VME AE G + D + + E
Sbjct: 49 EFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPE 108
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFA 424
+R + F+Q+VEA+ YCH GV HRD+KCEN L+ G N+KL+DFGFA+ + PK+
Sbjct: 109 SRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAK--VLPKSHR-E 164
Query: 423 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN 244
LS+TFCGS AYA+PE+L+G+P+ + DVWSMGVVLY ++ LPFDDT+ ++L Q Q
Sbjct: 165 LSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQK 224
Query: 243 KVSFPREPKVSAECRKLITRILAP-LKMRVKIPQILADPWL 124
VSFP +SA+C+ L+ R+L P + +R I ++ PWL
Sbjct: 225 GVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWL 265
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 210 bits (512), Expect = 6e-54
Identities = 99/221 (44%), Positives = 153/221 (69%), Gaps = 2/221 (0%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
+++++FLPRE+++V+ L H+N+I+ + +E+ ++ +VME AE G + D + + E
Sbjct: 49 EFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPE 108
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFA 424
+R + F+Q+VEA+ YCH GV HRD+KCEN L+ G N+KL+DFGFA+ + PK+
Sbjct: 109 SRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAK--VLPKSHR-E 164
Query: 423 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN 244
LS+TFCGS AYA+PE+L+G+P+ + DVWSMGVVLY ++ LPFDDT+ ++L Q Q
Sbjct: 165 LSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQK 224
Query: 243 KVSFPREPKVSAECRKLITRILAP-LKMRVKIPQILADPWL 124
VSFP +SA+C+ L+ R+L P + +R I ++ PWL
Sbjct: 225 GVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWL 265
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 210 bits (512), Expect = 6e-54
Identities = 99/221 (44%), Positives = 153/221 (69%), Gaps = 2/221 (0%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
+++++FLPRE+++V+ L H+N+I+ + +E+ ++ +VME AE G + D + + E
Sbjct: 49 EFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPE 108
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFA 424
+R + F+Q+VEA+ YCH GV HRD+KCEN L+ G N+KL+DFGFA+ + PK+
Sbjct: 109 SRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAK--VLPKSHR-E 164
Query: 423 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN 244
LS+TFCGS AYA+PE+L+G+P+ + DVWSMGVVLY ++ LPFDDT+ ++L Q Q
Sbjct: 165 LSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQK 224
Query: 243 KVSFPREPKVSAECRKLITRILAP-LKMRVKIPQILADPWL 124
VSFP +SA+C+ L+ R+L P + +R I ++ PWL
Sbjct: 225 GVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWL 265
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 210 bits (512), Expect = 6e-54
Identities = 99/221 (44%), Positives = 153/221 (69%), Gaps = 2/221 (0%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
+++++FLPRE+++V+ L H+N+I+ + +E+ ++ +VME AE G + D + + E
Sbjct: 49 EFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPE 108
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFA 424
+R + F+Q+VEA+ YCH GV HRD+KCEN L+ G N+KL+DFGFA+ + PK+
Sbjct: 109 SRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAK--VLPKSHR-E 164
Query: 423 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN 244
LS+TFCGS AYA+PE+L+G+P+ + DVWSMGVVLY ++ LPFDDT+ ++L Q Q
Sbjct: 165 LSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQK 224
Query: 243 KVSFPREPKVSAECRKLITRILAP-LKMRVKIPQILADPWL 124
VSFP +SA+C+ L+ R+L P + +R I ++ PWL
Sbjct: 225 GVSFPTHLSISADCQDLLKRLLEPDMILRPSIEEVSWHPWL 265
>BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein.
Length = 252
Score = 199 bits (486), Expect = 8e-51
Identities = 99/219 (45%), Positives = 139/219 (63%), Gaps = 13/219 (5%)
Frame = -1
Query: 741 VKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAV 562
+K L+H+ LI F +AIE+T RVYI++E A+ G +L+ I++ E +WF QL +
Sbjct: 1 MKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGI 60
Query: 561 DYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKN------------GVFA-L 421
Y H + +VHRD+K ENLL+D N+K+SDFGFA+ M P N F+ L
Sbjct: 61 AYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHL 118
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK 241
S+T+CGS+AYA PEIL+G+PY P SD WSMGV+LY +V LPFDDTN +LL++ Q +
Sbjct: 119 SQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKE 178
Query: 240 VSFPREPKVSAECRKLITRILAPLKMRVKIPQILADPWL 124
V+FP +S EC+ LI ++L R I I+ D W+
Sbjct: 179 VTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWV 217
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 175 bits (427), Expect = 1e-43
Identities = 88/224 (39%), Positives = 131/224 (58%), Gaps = 1/224 (0%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REIE++ L H ++I + E ++ I+MEYA G L D I + + + E R +F+Q
Sbjct: 139 REIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQ 198
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH+ GVVHRD+K EN+L+D NIK++DFG + + K K +TFCGS
Sbjct: 199 IVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDK-----FLQTFCGSP 253
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YASPEI+ G PYR + D W++GV+LY +VYG +PFD ++ L++Q+ + REP
Sbjct: 254 LYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISS--GEYREPT 311
Query: 216 VSAECRKLIT-RILAPLKMRVKIPQILADPWLNPNQQSKHDETD 88
++ R LI ++ R I I W+N +S + D
Sbjct: 312 QPSDARGLIRWMLMVNPDRRATIEDIANHWWVNWGYKSSVCDCD 355
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 175 bits (426), Expect = 1e-43
Identities = 90/228 (39%), Positives = 139/228 (60%), Gaps = 3/228 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y++MEYA G + D + + E R F+Q
Sbjct: 102 REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQ 161
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ + V +TFCGS
Sbjct: 162 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSN-----EFTVGGKLDTFCGSP 216
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 217 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 274
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 82
+S +C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 275 YMSTDCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 317
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 175 bits (426), Expect = 1e-43
Identities = 90/228 (39%), Positives = 139/228 (60%), Gaps = 3/228 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y++MEYA G + D + + E R F+Q
Sbjct: 102 REVRIMKILNHPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQ 161
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ + V +TFCGS
Sbjct: 162 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSN-----EFTVGGKLDTFCGSP 216
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 217 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 274
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 82
+S +C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 275 YMSTDCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 317
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 175 bits (426), Expect = 1e-43
Identities = 90/228 (39%), Positives = 139/228 (60%), Gaps = 3/228 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y++MEYA G + D + + E R F+Q
Sbjct: 102 REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQ 161
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ + V +TFCGS
Sbjct: 162 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSN-----EFTVGGKLDTFCGSP 216
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 217 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 274
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 82
+S +C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 275 YMSTDCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 317
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 175 bits (426), Expect = 1e-43
Identities = 90/228 (39%), Positives = 139/228 (60%), Gaps = 3/228 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y++MEYA G + D + + E R F+Q
Sbjct: 102 REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGKVFDYLVAHGRMKEKEARSKFRQ 161
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ + V +TFCGS
Sbjct: 162 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSN-----EFTVGGKLDTFCGSP 216
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 217 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 274
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 82
+S +C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 275 YMSTDCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 317
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 175 bits (426), Expect = 1e-43
Identities = 90/228 (39%), Positives = 139/228 (60%), Gaps = 3/228 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y++MEYA G + D + + E R F+Q
Sbjct: 102 REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQ 161
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ + V +TFCGS
Sbjct: 162 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSN-----EFTVGGKLDTFCGSP 216
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 217 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 274
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 82
+S +C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 275 YMSTDCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 317
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 174 bits (424), Expect = 3e-43
Identities = 90/232 (38%), Positives = 140/232 (60%), Gaps = 3/232 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 106 REVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 165
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ + V +TFCGS
Sbjct: 166 IVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSP 220
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 221 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 278
Query: 219 KVSAECRKLITRILA--PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
+S +C L+ ++L P+K R + QI+ D W+N H+E +L+ + +
Sbjct: 279 YMSTDCENLLKKLLVLNPIK-RGSLEQIMKDRWMNVG----HEEEELKPYTE 325
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 174 bits (424), Expect = 3e-43
Identities = 90/232 (38%), Positives = 140/232 (60%), Gaps = 3/232 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 106 REVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 165
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ + V +TFCGS
Sbjct: 166 IVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSP 220
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 221 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 278
Query: 219 KVSAECRKLITRILA--PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
+S +C L+ ++L P+K R + QI+ D W+N H+E +L+ + +
Sbjct: 279 YMSTDCENLLKKLLVLNPIK-RGSLEQIMKDRWMNVG----HEEEELKPYTE 325
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 174 bits (424), Expect = 3e-43
Identities = 90/232 (38%), Positives = 140/232 (60%), Gaps = 3/232 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 106 REVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 165
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ + V +TFCGS
Sbjct: 166 IVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSP 220
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 221 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 278
Query: 219 KVSAECRKLITRILA--PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
+S +C L+ ++L P+K R + QI+ D W+N H+E +L+ + +
Sbjct: 279 YMSTDCENLLKKLLVLNPIK-RGSLEQIMKDRWMNVG----HEEEELKPYTE 325
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 174 bits (424), Expect = 3e-43
Identities = 90/232 (38%), Positives = 140/232 (60%), Gaps = 3/232 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 106 REVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 165
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ + V +TFCGS
Sbjct: 166 IVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSP 220
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 221 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 278
Query: 219 KVSAECRKLITRILA--PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
+S +C L+ ++L P+K R + QI+ D W+N H+E +L+ + +
Sbjct: 279 YMSTDCENLLKKLLVLNPIK-RGSLEQIMKDRWMNVG----HEEEELKPYTE 325
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 174 bits (423), Expect = 3e-43
Identities = 86/215 (40%), Positives = 132/215 (61%), Gaps = 3/215 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++KGL H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 105 REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQ 164
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF+ + + + +TFCGS
Sbjct: 165 IVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSN-----EFTLGSKLDTFCGSP 219
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + D+WS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 220 PYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF-- 277
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLN 121
+S +C ++ R +L P K R + QI+ D W+N
Sbjct: 278 YMSTDCESILRRFLVLNPAK-RCTLEQIMKDKWIN 311
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 174 bits (423), Expect = 3e-43
Identities = 86/215 (40%), Positives = 132/215 (61%), Gaps = 3/215 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++KGL H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 105 REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQ 164
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF+ + + + +TFCGS
Sbjct: 165 IVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSN-----EFTLGSKLDTFCGSP 219
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + D+WS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 220 PYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF-- 277
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLN 121
+S +C ++ R +L P K R + QI+ D W+N
Sbjct: 278 YMSTDCESILRRFLVLNPAK-RCTLEQIMKDKWIN 311
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 174 bits (423), Expect = 3e-43
Identities = 86/215 (40%), Positives = 132/215 (61%), Gaps = 3/215 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++KGL H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 105 REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQ 164
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF+ + + + +TFCGS
Sbjct: 165 IVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSN-----EFTLGSKLDTFCGSP 219
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + D+WS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 220 PYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF-- 277
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLN 121
+S +C ++ R +L P K R + QI+ D W+N
Sbjct: 278 YMSTDCESILRRFLVLNPAK-RCTLEQIMKDKWIN 311
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 174 bits (423), Expect = 3e-43
Identities = 86/215 (40%), Positives = 132/215 (61%), Gaps = 3/215 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++KGL H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 105 REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQ 164
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF+ + + + +TFCGS
Sbjct: 165 IVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSN-----EFTLGSKLDTFCGSP 219
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + D+WS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 220 PYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF-- 277
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLN 121
+S +C ++ R +L P K R + QI+ D W+N
Sbjct: 278 YMSTDCESILRRFLVLNPAK-RCTLEQIMKDKWIN 311
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 174 bits (423), Expect = 3e-43
Identities = 86/215 (40%), Positives = 132/215 (61%), Gaps = 3/215 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++KGL H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 106 REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQ 165
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF+ + + + +TFCGS
Sbjct: 166 IVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSN-----EFTLGSKLDTFCGSP 220
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + D+WS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 221 PYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF-- 278
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLN 121
+S +C ++ R +L P K R + QI+ D W+N
Sbjct: 279 YMSTDCESILRRFLVLNPAK-RCTLEQIMKDKWIN 312
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 174 bits (423), Expect = 3e-43
Identities = 86/215 (40%), Positives = 132/215 (61%), Gaps = 3/215 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++KGL H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 105 REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQ 164
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D NIK++DFGF+ + + + +TFCGS
Sbjct: 165 IVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSN-----EFTLGSKLDTFCGSP 219
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + D+WS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 220 PYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF-- 277
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLN 121
+S +C ++ R +L P K R + QI+ D W+N
Sbjct: 278 YMSTDCESILRRFLVLNPAK-RCTLEQIMKDKWIN 311
>BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine
kinase 6 protein.
Length = 273
Score = 171 bits (417), Expect = 2e-42
Identities = 89/222 (40%), Positives = 136/222 (61%), Gaps = 3/222 (1%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
D++ KFLPRE+ +++G++H +++ + IE + ++YIVME A LL ++++ I
Sbjct: 51 DFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPG 109
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHG-LNIKLSDFGFARGHMKPKNGVF 427
+ R F Q+ AV Y H+ +VHRD+KCEN+L+ +KL+DFGF R +G
Sbjct: 110 VQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR----QAHGYP 165
Query: 426 ALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ 247
LS T+CGS AYASPE+L G+PY P+ DVWSMGVVLY +V G +PFDD++ L ++ +
Sbjct: 166 DLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQK 225
Query: 246 NKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQILADPWL 124
V +P ++S C+ LI +L R Q+ + WL
Sbjct: 226 RGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWL 267
>AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protein
kinase SSTK protein.
Length = 273
Score = 171 bits (417), Expect = 2e-42
Identities = 89/222 (40%), Positives = 136/222 (61%), Gaps = 3/222 (1%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
D++ KFLPRE+ +++G++H +++ + IE + ++YIVME A LL ++++ I
Sbjct: 51 DFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPG 109
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHG-LNIKLSDFGFARGHMKPKNGVF 427
+ R F Q+ AV Y H+ +VHRD+KCEN+L+ +KL+DFGF R +G
Sbjct: 110 VQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR----QAHGYP 165
Query: 426 ALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ 247
LS T+CGS AYASPE+L G+PY P+ DVWSMGVVLY +V G +PFDD++ L ++ +
Sbjct: 166 DLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQK 225
Query: 246 NKVSFPREPKVSAECRKLITRILA-PLKMRVKIPQILADPWL 124
V +P ++S C+ LI +L R Q+ + WL
Sbjct: 226 RGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWL 267
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 171 bits (415), Expect = 3e-42
Identities = 89/232 (38%), Positives = 137/232 (59%), Gaps = 3/232 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 66 REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 125
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ +TFCGS
Sbjct: 126 IVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSP 180
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 181 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 238
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
+S +C L+ + IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 239 YMSTDCENLLKKFLILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 285
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 171 bits (415), Expect = 3e-42
Identities = 89/232 (38%), Positives = 137/232 (59%), Gaps = 3/232 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 66 REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 125
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ +TFCGS
Sbjct: 126 IVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSP 180
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 181 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 238
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
+S +C L+ + IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 239 YMSTDCENLLKKFLILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 285
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 171 bits (415), Expect = 3e-42
Identities = 89/232 (38%), Positives = 137/232 (59%), Gaps = 3/232 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 99 REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 158
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ +TFCGS
Sbjct: 159 IVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSP 213
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 214 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 271
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
+S +C L+ + IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 272 YMSTDCENLLKKFLILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 318
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 171 bits (415), Expect = 3e-42
Identities = 83/212 (39%), Positives = 126/212 (59%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REIE++ L H ++I + E + ++ IVMEYA G L D I + Q + E R +F+Q
Sbjct: 99 REIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQ 158
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH+ VVHRD+K EN+L+D NIK++DFG + + + K +TFCGS
Sbjct: 159 IVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGK-----FLQTFCGSP 213
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YASPEI+ G PY + D WS+GV+LY +V+G +PFD ++ L+KQ+ N ++ PK
Sbjct: 214 LYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNG-AYREPPK 272
Query: 216 VSAECRKLITRILAPLKMRVKIPQILADPWLN 121
S C + ++ R + + + W+N
Sbjct: 273 PSDACGLIRWLLMVNPTRRATLEDVASHWWVN 304
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 171 bits (415), Expect = 3e-42
Identities = 89/232 (38%), Positives = 137/232 (59%), Gaps = 3/232 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 89 REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 148
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ +TFCGS
Sbjct: 149 IVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSP 203
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 204 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 261
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
+S +C L+ + IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 262 YMSTDCENLLKKFLILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 308
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 171 bits (415), Expect = 3e-42
Identities = 83/212 (39%), Positives = 126/212 (59%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REIE++ L H ++I + E + ++ IVMEYA G L D I + Q + E R +F+Q
Sbjct: 99 REIEIMSSLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQ 158
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH+ VVHRD+K EN+L+D NIK++DFG + + + K +TFCGS
Sbjct: 159 IVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGK-----FLQTFCGSP 213
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YASPEI+ G PY + D WS+GV+LY +V+G +PFD ++ L+KQ+ N ++ PK
Sbjct: 214 LYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNG-AYREPPK 272
Query: 216 VSAECRKLITRILAPLKMRVKIPQILADPWLN 121
S C + ++ R + + + W+N
Sbjct: 273 PSDACGLIRWLLMVNPTRRATLEDVASHWWVN 304
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 171 bits (415), Expect = 3e-42
Identities = 89/232 (38%), Positives = 137/232 (59%), Gaps = 3/232 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 66 REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 125
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ +TFCGS
Sbjct: 126 IVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSP 180
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 181 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 238
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
+S +C L+ + IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 239 YMSTDCENLLKKFLILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 285
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 171 bits (415), Expect = 3e-42
Identities = 89/232 (38%), Positives = 137/232 (59%), Gaps = 3/232 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y+VMEYA G + D + + E R F+Q
Sbjct: 99 REVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQ 158
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFGF+ +TFCGS
Sbjct: 159 IVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSP 213
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P
Sbjct: 214 PYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF-- 271
Query: 219 KVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
+S +C L+ + IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 272 YMSTDCENLLKKFLILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 318
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 170 bits (413), Expect = 6e-42
Identities = 90/213 (42%), Positives = 130/213 (61%), Gaps = 2/213 (0%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE++++K L H ++I+ Q +ET +Y+V EYA+NG + D + ++E+ RR F Q
Sbjct: 66 REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQ 125
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ AVDYCH R +VHRD+K ENLL+D+ +NIK++DFGF K+G L T+CGS
Sbjct: 126 ILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSP 180
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA+PE+ +G Y D+WSMGVVLY +V G LPFD +L+Q + F
Sbjct: 181 PYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYF 239
Query: 216 VSAECRKLITR--ILAPLKMRVKIPQILADPWL 124
+S +C LI R +L P K R+ I QI W+
Sbjct: 240 MSEDCEHLIRRMLVLDPSK-RLTIAQIKEHKWM 271
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 170 bits (413), Expect = 6e-42
Identities = 90/213 (42%), Positives = 130/213 (61%), Gaps = 2/213 (0%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE++++K L H ++I+ Q +ET +Y+V EYA+NG + D + ++E+ RR F Q
Sbjct: 66 REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQ 125
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ AVDYCH R +VHRD+K ENLL+D+ +NIK++DFGF K+G L T+CGS
Sbjct: 126 ILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSP 180
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA+PE+ +G Y D+WSMGVVLY +V G LPFD +L+Q + F
Sbjct: 181 PYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYF 239
Query: 216 VSAECRKLITR--ILAPLKMRVKIPQILADPWL 124
+S +C LI R +L P K R+ I QI W+
Sbjct: 240 MSEDCEHLIRRMLVLDPSK-RLTIAQIKEHKWM 271
>AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens
cDNA FLJ24002 fis, clone KAIA4350, highly similar to
Homo sapiens serine/threonine protein kinase SSTK
(SSTK). ).
Length = 406
Score = 170 bits (413), Expect = 6e-42
Identities = 87/215 (40%), Positives = 135/215 (62%), Gaps = 4/215 (1%)
Frame = -1
Query: 780 DYLKKFLPREIEVVKGLKHENLIRFLQAIETTH-RVYIVMEYAENGSLLDIIRKDQHIDE 604
D++ KFLPRE+ +++G++H +++ + IE + ++YIVME A LL ++++ I
Sbjct: 51 DFVNKFLPRELSILRGVRHPHIVHVFEFIEVCNGKLYIVMEAAAT-DLLQAVQRNGRIPG 109
Query: 603 TRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHG-LNIKLSDFGFARGHMKPKNGVF 427
+ R F Q+ AV Y H+ +VHRD+KCEN+L+ +KL+DFGF R +G
Sbjct: 110 VQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR----QAHGYP 165
Query: 426 ALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ 247
LS T+CGS AYASPE+L G+PY P+ DVWSMGVVLY +V G +PFDD++ L ++ +
Sbjct: 166 DLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQK 225
Query: 246 NKVSFPREPKVSAECRKLITRILA--PLKMRVKIP 148
V +P ++S C+ LI A P++ ++ P
Sbjct: 226 RGVLYPEGLELSERCKALIAEAAAVQPVRQALRGP 260
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 170 bits (413), Expect = 6e-42
Identities = 90/213 (42%), Positives = 130/213 (61%), Gaps = 2/213 (0%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE++++K L H ++I+ Q +ET +Y+V EYA+NG + D + ++E+ RR F Q
Sbjct: 64 REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQ 123
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ AVDYCH R +VHRD+K ENLL+D+ +NIK++DFGF K+G L T+CGS
Sbjct: 124 ILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSP 178
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA+PE+ +G Y D+WSMGVVLY +V G LPFD +L+Q + F
Sbjct: 179 PYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYF 237
Query: 216 VSAECRKLITR--ILAPLKMRVKIPQILADPWL 124
+S +C LI R +L P K R+ I QI W+
Sbjct: 238 MSEDCEHLIRRMLVLDPSK-RLTIAQIKEHKWM 269
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 170 bits (413), Expect = 6e-42
Identities = 90/213 (42%), Positives = 130/213 (61%), Gaps = 2/213 (0%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE++++K L H ++I+ Q +ET +Y+V EYA+NG + D + ++E+ RR F Q
Sbjct: 90 REVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQ 149
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ AVDYCH R +VHRD+K ENLL+D+ +NIK++DFGF K+G L T+CGS
Sbjct: 150 ILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSP 204
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA+PE+ +G Y D+WSMGVVLY +V G LPFD +L+Q + F
Sbjct: 205 PYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYF 263
Query: 216 VSAECRKLITR--ILAPLKMRVKIPQILADPWL 124
+S +C LI R +L P K R+ I QI W+
Sbjct: 264 MSEDCEHLIRRMLVLDPSK-RLTIAQIKEHKWM 295
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 167 bits (405), Expect = 5e-41
Identities = 88/214 (41%), Positives = 133/214 (62%), Gaps = 3/214 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE++++K L H ++I+ Q +ET +YIV E+A+NG + D + + H+ E R+ F Q
Sbjct: 73 REVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQ 132
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ AV+YCH+ +VHRD+K ENLL+D ++IKL+DFGF + K+G LS T+CGS
Sbjct: 133 ILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSP 187
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y D+WS+GVVLY +V G LPFD N L ++V + + P
Sbjct: 188 PYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF-- 245
Query: 219 KVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
+S +C LI R+L P + R+ I QI W+
Sbjct: 246 FMSQDCESLIRRMLVVDPAR-RITIAQIRQHRWM 278
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 167 bits (405), Expect = 5e-41
Identities = 88/214 (41%), Positives = 133/214 (62%), Gaps = 3/214 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE++++K L H ++I+ Q +ET +YIV E+A+NG + D + + H+ E R+ F Q
Sbjct: 54 REVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQ 113
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ AV+YCH+ +VHRD+K ENLL+D ++IKL+DFGF + K+G LS T+CGS
Sbjct: 114 ILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSP 168
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y D+WS+GVVLY +V G LPFD N L ++V + + P
Sbjct: 169 PYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF-- 226
Query: 219 KVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
+S +C LI R+L P + R+ I QI W+
Sbjct: 227 FMSQDCESLIRRMLVVDPAR-RITIAQIRQHRWM 259
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 167 bits (405), Expect = 5e-41
Identities = 88/214 (41%), Positives = 133/214 (62%), Gaps = 3/214 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE++++K L H ++I+ Q +ET +YIV E+A+NG + D + + H+ E R+ F Q
Sbjct: 73 REVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQ 132
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ AV+YCH+ +VHRD+K ENLL+D ++IKL+DFGF + K+G LS T+CGS
Sbjct: 133 ILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSP 187
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
YA+PE+ +G Y D+WS+GVVLY +V G LPFD N L ++V + + P
Sbjct: 188 PYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF-- 245
Query: 219 KVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
+S +C LI R+L P + R+ I QI W+
Sbjct: 246 FMSQDCESLIRRMLVVDPAR-RITIAQIRQHRWM 278
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 161 bits (390), Expect = 3e-39
Identities = 88/217 (40%), Positives = 133/217 (61%), Gaps = 6/217 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE++++K L H ++I+ Q +ET +YIV E+A+NG + D + + H+ E R+ F Q
Sbjct: 73 REVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQ 132
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLS---DFGFARGHMKPKNGVFALSETFC 406
++ AV+YCH+ +VHRD+K ENLL+D ++IKL+ DFGF + K+G LS T+C
Sbjct: 133 ILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLAGTEDFGFGNFY---KSGE-PLS-TWC 187
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 229
GS YA+PE+ +G Y D+WS+GVVLY +V G LPFD N L ++V + + P
Sbjct: 188 GSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIP 247
Query: 228 REPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
+S +C LI R+L P + R+ I QI W+
Sbjct: 248 F--FMSQDCESLIRRMLVVDPAR-RITIAQIRQHRWM 281
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 160 bits (388), Expect = 6e-39
Identities = 91/220 (41%), Positives = 127/220 (57%), Gaps = 3/220 (1%)
Frame = -1
Query: 774 LKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRG 595
LKK RE++++K L H ++IR Q +ET +Y+V EYA G + D + + E
Sbjct: 49 LKKIF-REVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEA 107
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSE 415
RR FKQ+V AV +CH R +VHRD+K ENLL+D LNIK++DFGF+ + L +
Sbjct: 108 RRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ-----LLK 162
Query: 414 TFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKV 238
T+CGS YA+PE+ +G Y D+WS+GVVLY +V G LPFD + L +V K
Sbjct: 163 TWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKF 222
Query: 237 SFPREPKVSAECRKLITR--ILAPLKMRVKIPQILADPWL 124
P +S EC LI +L P K R+ + QI W+
Sbjct: 223 RIPF--FMSTECEHLIRHMLVLDPNK-RLSMEQICKHKWM 259
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 160 bits (388), Expect = 6e-39
Identities = 91/220 (41%), Positives = 127/220 (57%), Gaps = 3/220 (1%)
Frame = -1
Query: 774 LKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRG 595
LKK RE++++K L H ++IR Q +ET +Y+V EYA G + D + + E
Sbjct: 157 LKKIF-REVQIMKMLCHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEA 215
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSE 415
RR FKQ+V AV +CH R +VHRD+K ENLL+D LNIK++DFGF+ + L +
Sbjct: 216 RRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ-----LLK 270
Query: 414 TFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKV 238
T+CGS YA+PE+ +G Y D+WS+GVVLY +V G LPFD + L +V K
Sbjct: 271 TWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKF 330
Query: 237 SFPREPKVSAECRKLITR--ILAPLKMRVKIPQILADPWL 124
P +S EC LI +L P K R+ + QI W+
Sbjct: 331 RIPF--FMSTECEHLIRHMLVLDPNK-RLSMEQICKHKWM 367
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 134 bits (325), Expect(2) = 1e-38
Identities = 70/179 (39%), Positives = 107/179 (59%), Gaps = 3/179 (1%)
Frame = -1
Query: 648 GSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDF 469
G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D NIK++DF
Sbjct: 171 GEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADF 230
Query: 468 GFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLP 289
GF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+LY +V G LP
Sbjct: 231 GFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLP 285
Query: 288 FDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIPQILADPWLN 121
FD N +L ++V + K P +S +C ++ R +L P K R + QI+ D W+N
Sbjct: 286 FDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLEQIMKDKWIN 341
Score = 46.0 bits (104), Expect(2) = 1e-38
Identities = 17/37 (45%), Positives = 26/37 (70%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG 646
RE+ ++KGL H N+++ + IET +Y+VMEYA G
Sbjct: 105 REVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAG 141
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 156 bits (378), Expect = 1e-37
Identities = 83/218 (38%), Positives = 125/218 (57%), Gaps = 5/218 (2%)
Frame = -1
Query: 762 LPR---EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
LPR EIE +K L+H+++ + +ET +++++V+EY G L D I + E R
Sbjct: 56 LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETR 115
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
F+Q+V AV Y H +G HRD+K ENLL D +KL DFG KPK +T
Sbjct: 116 VVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC---AKPKGNKDYHLQT 172
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVS 235
CGS AYA+PE+++G Y ++DVWSMG++LY ++ G LPFDD N L K++ + K
Sbjct: 173 CCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYD 232
Query: 234 FPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P+ +S L+ ++L K R+ + +L PW+
Sbjct: 233 VPK--WLSPSSILLLQQMLQVDPKKRISMKNLLNHPWI 268
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 156 bits (378), Expect = 1e-37
Identities = 83/218 (38%), Positives = 125/218 (57%), Gaps = 5/218 (2%)
Frame = -1
Query: 762 LPR---EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
LPR EIE +K L+H+++ + +ET +++++V+EY G L D I + E R
Sbjct: 51 LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETR 110
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
F+Q+V AV Y H +G HRD+K ENLL D +KL DFG KPK +T
Sbjct: 111 VVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC---AKPKGNKDYHLQT 167
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVS 235
CGS AYA+PE+++G Y ++DVWSMG++LY ++ G LPFDD N L K++ + K
Sbjct: 168 CCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYD 227
Query: 234 FPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P+ +S L+ ++L K R+ + +L PW+
Sbjct: 228 VPK--WLSPSSILLLQQMLQVDPKKRISMKNLLNHPWI 263
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 156 bits (378), Expect = 1e-37
Identities = 83/218 (38%), Positives = 125/218 (57%), Gaps = 5/218 (2%)
Frame = -1
Query: 762 LPR---EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
LPR EIE +K L+H+++ + +ET +++++V+EY G L D I + E R
Sbjct: 51 LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETR 110
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
F+Q+V AV Y H +G HRD+K ENLL D +KL DFG KPK +T
Sbjct: 111 VVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC---AKPKGNKDYHLQT 167
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVS 235
CGS AYA+PE+++G Y ++DVWSMG++LY ++ G LPFDD N L K++ + K
Sbjct: 168 CCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYD 227
Query: 234 FPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P+ +S L+ ++L K R+ + +L PW+
Sbjct: 228 VPK--WLSPSSILLLQQMLQVDPKKRISMKNLLNHPWI 263
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 156 bits (378), Expect = 1e-37
Identities = 83/218 (38%), Positives = 125/218 (57%), Gaps = 5/218 (2%)
Frame = -1
Query: 762 LPR---EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
LPR EIE +K L+H+++ + +ET +++++V+EY G L D I + E R
Sbjct: 51 LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETR 110
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
F+Q+V AV Y H +G HRD+K ENLL D +KL DFG KPK +T
Sbjct: 111 VVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC---AKPKGNKDYHLQT 167
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVS 235
CGS AYA+PE+++G Y ++DVWSMG++LY ++ G LPFDD N L K++ + K
Sbjct: 168 CCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYD 227
Query: 234 FPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P+ +S L+ ++L K R+ + +L PW+
Sbjct: 228 VPK--WLSPSSILLLQQMLQVDPKKRISMKNLLNHPWI 263
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 156 bits (378), Expect = 1e-37
Identities = 83/218 (38%), Positives = 125/218 (57%), Gaps = 5/218 (2%)
Frame = -1
Query: 762 LPR---EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
LPR EIE +K L+H+++ + +ET +++++V+EY G L D I + E R
Sbjct: 51 LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETR 110
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
F+Q+V AV Y H +G HRD+K ENLL D +KL DFG KPK +T
Sbjct: 111 VVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC---AKPKGNKDYHLQT 167
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVS 235
CGS AYA+PE+++G Y ++DVWSMG++LY ++ G LPFDD N L K++ + K
Sbjct: 168 CCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYD 227
Query: 234 FPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P+ +S L+ ++L K R+ + +L PW+
Sbjct: 228 VPK--WLSPSSILLLQQMLQVDPKKRISMKNLLNHPWI 263
>AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leucine
zipper kinase v2 protein.
Length = 619
Score = 156 bits (378), Expect = 1e-37
Identities = 83/218 (38%), Positives = 125/218 (57%), Gaps = 5/218 (2%)
Frame = -1
Query: 762 LPR---EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
LPR EIE +K L+H+++ + +ET +++++V+EY G L D I + E R
Sbjct: 19 LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETR 78
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
F+Q+V AV Y H +G HRD+K ENLL D +KL DFG KPK +T
Sbjct: 79 VVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLC---AKPKGNKDYHLQT 135
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVS 235
CGS AYA+PE+++G Y ++DVWSMG++LY ++ G LPFDD N L K++ + K
Sbjct: 136 CCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYD 195
Query: 234 FPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P+ +S L+ ++L K R+ + +L PW+
Sbjct: 196 VPK--WLSPSSILLLQQMLQVDPKKRISMKNLLNHPWI 231
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 153 bits (372), Expect = 5e-37
Identities = 76/211 (36%), Positives = 125/211 (59%), Gaps = 1/211 (0%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 80 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 139
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 140 IVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 194
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE++KG Y + +D+WS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 195 HYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 253
Query: 216 VSAECRKLITRIL-APLKMRVKIPQILADPW 127
+ +C+ L+ ++ + R+ + QI PW
Sbjct: 254 IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 284
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 153 bits (372), Expect = 5e-37
Identities = 76/211 (36%), Positives = 125/211 (59%), Gaps = 1/211 (0%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 80 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 139
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 140 IVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 194
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE++KG Y + +D+WS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 195 HYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 253
Query: 216 VSAECRKLITRIL-APLKMRVKIPQILADPW 127
+ +C+ L+ ++ + R+ + QI PW
Sbjct: 254 IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 284
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 153 bits (372), Expect = 5e-37
Identities = 76/211 (36%), Positives = 125/211 (59%), Gaps = 1/211 (0%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 80 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 139
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 140 IVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 194
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE++KG Y + +D+WS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 195 HYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 253
Query: 216 VSAECRKLITRIL-APLKMRVKIPQILADPW 127
+ +C+ L+ ++ + R+ + QI PW
Sbjct: 254 IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 284
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 153 bits (372), Expect = 5e-37
Identities = 76/211 (36%), Positives = 125/211 (59%), Gaps = 1/211 (0%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 96 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 155
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 156 IVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 210
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE++KG Y + +D+WS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 211 HYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 269
Query: 216 VSAECRKLITRIL-APLKMRVKIPQILADPW 127
+ +C+ L+ ++ + R+ + QI PW
Sbjct: 270 IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 300
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 153 bits (372), Expect = 5e-37
Identities = 76/211 (36%), Positives = 125/211 (59%), Gaps = 1/211 (0%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 17 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 76
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
+V A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 77 IVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 131
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE++KG Y + +D+WS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 132 HYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 190
Query: 216 VSAECRKLITRIL-APLKMRVKIPQILADPW 127
+ +C+ L+ ++ + R+ + QI PW
Sbjct: 191 IPPDCQSLLRGMIEVEPEKRLSLEQIQKHPW 221
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 153 bits (370), Expect = 9e-37
Identities = 90/251 (35%), Positives = 138/251 (54%), Gaps = 26/251 (10%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
RE+ ++K L H N+++ + IET +Y++MEYA G + D + + E R F+Q
Sbjct: 102 REVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQ 161
Query: 576 -----------------------LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFG 466
+V AV YCH++ +VHRD+K ENLL+D +NIK++DFG
Sbjct: 162 GCQAGQTIKVQVSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFG 221
Query: 465 FARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPF 286
F+ V +TFCGS YA+PE+ +G Y + DVWS+GV+LY +V G LPF
Sbjct: 222 FSNEFT-----VGGKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPF 276
Query: 285 DDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIPQILADPWLNPN 115
D N +L ++V + K P +S +C L+ R +L P+K R + QI+ D W+N
Sbjct: 277 DGQNLKELRERVLRGKYRIPF--YMSTDCENLLKRFLVLNPIK-RGTLEQIMKDRWIN-- 331
Query: 114 QQSKHDETDLQ 82
+ H+E +L+
Sbjct: 332 --AGHEEDELK 340
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 152 bits (368), Expect = 2e-36
Identities = 84/221 (38%), Positives = 124/221 (56%), Gaps = 2/221 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ REI+ +K +H ++I+ Q I T ++VMEY G L D I K ++E RR F
Sbjct: 61 IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF 120
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG + +G F T CG
Sbjct: 121 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCG 175
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
S YA+PE++ G Y + D+WS GV+LYA++ G LPFDD + L K+++ V + E
Sbjct: 176 SPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE 235
Query: 222 PKVSAECRKLITRILA--PLKMRVKIPQILADPWLNPNQQS 106
++ L+ +L PLK R I I W + S
Sbjct: 236 -YLNRSVATLLMHMLQVDPLK-RATIKDIREHEWFKQDLPS 274
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 152 bits (368), Expect = 2e-36
Identities = 84/221 (38%), Positives = 124/221 (56%), Gaps = 2/221 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ REI+ +K +H ++I+ Q I T ++VMEY G L D I K ++E RR F
Sbjct: 61 IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF 120
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG + +G F T CG
Sbjct: 121 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCG 175
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
S YA+PE++ G Y + D+WS GV+LYA++ G LPFDD + L K+++ V + E
Sbjct: 176 SPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE 235
Query: 222 PKVSAECRKLITRILA--PLKMRVKIPQILADPWLNPNQQS 106
++ L+ +L PLK R I I W + S
Sbjct: 236 -YLNRSVATLLMHMLQVDPLK-RATIKDIREHEWFKQDLPS 274
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 152 bits (368), Expect = 2e-36
Identities = 84/221 (38%), Positives = 124/221 (56%), Gaps = 2/221 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ REI+ +K +H ++I+ Q I T ++VMEY G L D I K ++E RR F
Sbjct: 61 IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF 120
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG + +G F T CG
Sbjct: 121 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCG 175
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
S YA+PE++ G Y + D+WS GV+LYA++ G LPFDD + L K+++ V + E
Sbjct: 176 SPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE 235
Query: 222 PKVSAECRKLITRILA--PLKMRVKIPQILADPWLNPNQQS 106
++ L+ +L PLK R I I W + S
Sbjct: 236 -YLNRSVATLLMHMLQVDPLK-RATIKDIREHEWFKQDLPS 274
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 152 bits (368), Expect = 2e-36
Identities = 84/221 (38%), Positives = 124/221 (56%), Gaps = 2/221 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ REI+ +K +H ++I+ Q I T ++VMEY G L D I K ++E RR F
Sbjct: 61 IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF 120
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG + +G F T CG
Sbjct: 121 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCG 175
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
S YA+PE++ G Y + D+WS GV+LYA++ G LPFDD + L K+++ V + E
Sbjct: 176 SPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE 235
Query: 222 PKVSAECRKLITRILA--PLKMRVKIPQILADPWLNPNQQS 106
++ L+ +L PLK R I I W + S
Sbjct: 236 -YLNRSVATLLMHMLQVDPLK-RATIKDIREHEWFKQDLPS 274
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 152 bits (368), Expect = 2e-36
Identities = 84/221 (38%), Positives = 124/221 (56%), Gaps = 2/221 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ REI+ +K +H ++I+ Q I T ++VMEY G L D I K ++E RR F
Sbjct: 61 IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF 120
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG + +G F T CG
Sbjct: 121 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCG 175
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
S YA+PE++ G Y + D+WS GV+LYA++ G LPFDD + L K+++ V + E
Sbjct: 176 SPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE 235
Query: 222 PKVSAECRKLITRILA--PLKMRVKIPQILADPWLNPNQQS 106
++ L+ +L PLK R I I W + S
Sbjct: 236 -YLNRSVATLLMHMLQVDPLK-RATIKDIREHEWFKQDLPS 274
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 151 bits (367), Expect = 2e-36
Identities = 86/246 (34%), Positives = 144/246 (58%), Gaps = 8/246 (3%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFK 580
+E+ +K ++H N++R + I+T ++Y+++E + G + D I K ++ ++E +++F
Sbjct: 63 QEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFA 122
Query: 579 QLVEAVDYCHERGVVHRDIKCENLLM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
Q+V A+ YCH+ VVHRD+K EN++ GL +KL+DFGF+ K T C
Sbjct: 123 QIVHAISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSC 176
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 229
GS AY++PEIL G Y D+WS+GV+L+ +V G+ PF + N ++ L + + K + P
Sbjct: 177 GSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVP 236
Query: 228 REPKVSAECRKLITRIL-APLKMRVKIPQILADPWL---NPNQQSKHDETDLQEHAKTSK 61
VS EC+ LITR+L K R + +I PWL +P+ +K++ L + S+
Sbjct: 237 SH--VSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSE 293
Query: 60 EEIKSV 43
EE S+
Sbjct: 294 EEHNSI 299
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 151 bits (366), Expect = 3e-36
Identities = 81/213 (38%), Positives = 124/213 (58%), Gaps = 3/213 (1%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI+ +K +H ++I+ Q I T +++VMEY G L D I K+ +DE RR F+Q
Sbjct: 65 REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQ 124
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ VDYCH VVHRD+K EN+L+D +N K++DFG + +G F T CGS
Sbjct: 125 ILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSP 179
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSF-PR-- 226
YA+PE++ G Y + D+WS GV+LYA++ G LPFDD + L K++ + + + P+
Sbjct: 180 NYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYL 239
Query: 225 EPKVSAECRKLITRILAPLKMRVKIPQILADPW 127
P V + + ++ + P+K R I I W
Sbjct: 240 NPSVISLLKHMLQ--VDPMK-RASIKDIREHEW 269
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 151 bits (365), Expect = 4e-36
Identities = 86/246 (34%), Positives = 144/246 (58%), Gaps = 8/246 (3%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFK 580
+E+ +K ++H N++R + I+T ++Y+++E + G + D I K ++ ++E +++F
Sbjct: 62 QEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFA 121
Query: 579 QLVEAVDYCHERGVVHRDIKCENLLM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
Q+V A+ YCH+ VVHRD+K EN++ GL +KL+DFGF+ K T C
Sbjct: 122 QIVHAISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSC 175
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 229
GS AY++PEIL G Y D+WS+GV+L+ +V G+ PF + N ++ L + + K + P
Sbjct: 176 GSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVP 235
Query: 228 REPKVSAECRKLITRIL-APLKMRVKIPQILADPWL---NPNQQSKHDETDLQEHAKTSK 61
VS EC+ LITR+L K R + +I PWL +P+ +K++ L + S+
Sbjct: 236 SH--VSKECKDLITRMLQRDPKRRAYLEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSE 292
Query: 60 EEIKSV 43
EE S+
Sbjct: 293 EEHNSI 298
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 151 bits (365), Expect = 4e-36
Identities = 72/169 (42%), Positives = 105/169 (62%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI+ +K +H ++I+ Q I T +++VMEY G L D I K+ +DE RR F+Q
Sbjct: 65 REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQ 124
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ VDYCH VVHRD+K EN+L+D +N K++DFG + +G F T CGS
Sbjct: 125 ILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSP 179
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV 250
YA+PE++ G Y + D+WS GV+LYA++ G LPFDD + L K++
Sbjct: 180 NYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKI 228
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 151 bits (365), Expect = 4e-36
Identities = 86/246 (34%), Positives = 144/246 (58%), Gaps = 8/246 (3%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFK 580
+E+ +K ++H N++R + I+T ++Y+++E + G + D I K ++ ++E +++F
Sbjct: 62 QEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDEGDMFDYIMKHEEGLNEDLPKKYFA 121
Query: 579 QLVEAVDYCHERGVVHRDIKCENLLM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
Q+V A+ YCH+ VVHRD+K EN++ GL +KL+DFGF+ K T C
Sbjct: 122 QIVHAISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSC 175
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 229
GS AY++PEIL G Y D+WS+GV+L+ +V G+ PF + N ++ L + + K + P
Sbjct: 176 GSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVP 235
Query: 228 REPKVSAECRKLITRIL-APLKMRVKIPQILADPWL---NPNQQSKHDETDLQEHAKTSK 61
VS EC+ LITR+L K R + +I PWL +P+ +K++ L + S+
Sbjct: 236 SH--VSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSE 292
Query: 60 EEIKSV 43
EE S+
Sbjct: 293 EEHNSI 298
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 150 bits (363), Expect = 6e-36
Identities = 82/214 (38%), Positives = 121/214 (56%), Gaps = 2/214 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ REI+ +K +H ++I+ Q I T ++VMEY G L D I K ++E RR F
Sbjct: 61 IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLF 120
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+Q++ AVDYCH VVHRD+K EN+L+D +N K++DFG + +G F T CG
Sbjct: 121 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCG 175
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
S Y +PE++ G Y + D+WS GV+LYA++ G LPFDD + L K+++ V + E
Sbjct: 176 SPNYTAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE 235
Query: 222 PKVSAECRKLITRILA--PLKMRVKIPQILADPW 127
++ L+ +L PLK R I I W
Sbjct: 236 -YLNRSVATLLMHMLQVDPLK-RATIKDIREHEW 267
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 149 bits (362), Expect = 8e-36
Identities = 86/231 (37%), Positives = 133/231 (57%), Gaps = 6/231 (2%)
Frame = -1
Query: 777 YLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETR 598
Y+ K L RE ++ + ++H N+ + L +ET + Y+VME G+L+ I + + ++E+
Sbjct: 103 YVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESE 162
Query: 597 GRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALS 418
RR+ +QL+ AV++ H GVVHRD+K ENLL+D NIKL DFG + G+ S
Sbjct: 163 ARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSN-----CAGILGYS 217
Query: 417 ETF---CGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPF--DDTNYTQLLKQ 253
+ F CGS AYA+PE+L Y P+ DVWS+GV +YA++ G LPF + + L ++
Sbjct: 218 DPFSTQCGSPAYAAPELLARKKYGPK-IDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQK 276
Query: 252 VQNKVSFPREPKVSAECRKLITRILAPLKM-RVKIPQILADPWLNPNQQSK 103
+ +K P ++S + +L P + R I Q LA+ WLN N K
Sbjct: 277 MVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTGK 327
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 148 bits (359), Expect = 2e-35
Identities = 70/189 (37%), Positives = 115/189 (60%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 65 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 124
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 125 IISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 179
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 238
Query: 216 VSAECRKLI 190
+ +C+ L+
Sbjct: 239 IPPDCQSLL 247
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 148 bits (359), Expect = 2e-35
Identities = 70/189 (37%), Positives = 115/189 (60%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 65 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 124
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 125 IISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 179
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 238
Query: 216 VSAECRKLI 190
+ +C+ L+
Sbjct: 239 IPPDCQSLL 247
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 148 bits (359), Expect = 2e-35
Identities = 70/189 (37%), Positives = 115/189 (60%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 111 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 170
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 171 IISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 225
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 226 HYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 284
Query: 216 VSAECRKLI 190
+ +C+ L+
Sbjct: 285 IPPDCQSLL 293
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 148 bits (359), Expect = 2e-35
Identities = 70/189 (37%), Positives = 115/189 (60%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 65 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 124
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 125 IISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 179
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 238
Query: 216 VSAECRKLI 190
+ +C+ L+
Sbjct: 239 IPPDCQSLL 247
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 148 bits (359), Expect = 2e-35
Identities = 70/189 (37%), Positives = 115/189 (60%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 65 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 124
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 125 IISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 179
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 238
Query: 216 VSAECRKLI 190
+ +C+ L+
Sbjct: 239 IPPDCQSLL 247
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 148 bits (359), Expect = 2e-35
Identities = 70/189 (37%), Positives = 115/189 (60%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 65 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 124
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 125 IISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 179
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 238
Query: 216 VSAECRKLI 190
+ +C+ L+
Sbjct: 239 IPPDCQSLL 247
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 148 bits (359), Expect = 2e-35
Identities = 70/189 (37%), Positives = 115/189 (60%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 65 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 124
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 125 IISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 179
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 238
Query: 216 VSAECRKLI 190
+ +C+ L+
Sbjct: 239 IPPDCQSLL 247
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 148 bits (359), Expect = 2e-35
Identities = 70/189 (37%), Positives = 115/189 (60%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI ++K ++H ++++ E +Y+V+E+ G L D + K + R++F+Q
Sbjct: 65 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 124
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ A+D+CH + HRD+K ENLL+D NI+++DFG A + +L ET CGS
Sbjct: 125 IISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSP 179
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
YA PE+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F
Sbjct: 180 HYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHF 238
Query: 216 VSAECRKLI 190
+ +C+ L+
Sbjct: 239 IPPDCQSLL 247
>AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens
cDNA FLJ14587 fis, clone NT2RM4001758, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK
(EC 2.7.1.-). ).
Length = 638
Score = 147 bits (355), Expect = 6e-35
Identities = 79/202 (39%), Positives = 120/202 (59%), Gaps = 3/202 (1%)
Frame = -1
Query: 666 MEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLN 487
MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D +N
Sbjct: 1 MEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMN 60
Query: 486 IKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAI 307
IK++DFGF+ + V +TFCGS YA+PE+ +G Y + DVWS+GV+LY +
Sbjct: 61 IKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTL 115
Query: 306 VYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQILA 136
V G LPFD N +L ++V + K P +S +C L+ ++L P+K R + QI+
Sbjct: 116 VSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RGSLEQIMK 172
Query: 135 DPWLNPNQQSKHDETDLQEHAK 70
D W+N H+E +L+ + +
Sbjct: 173 DRWMNVG----HEEEELKPYTE 190
>AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens
cDNA FLJ90097 fis, clone HEMBA1005929, weakly similar to
H.sapiens mRNA for serine/threonine protein kinase EMK.
).
Length = 426
Score = 142 bits (344), Expect = 1e-33
Identities = 74/185 (40%), Positives = 111/185 (60%), Gaps = 3/185 (1%)
Frame = -1
Query: 666 MEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLN 487
MEYA G + D + + E R F+Q+V AV YCH++ +VHRD+K ENLL+D N
Sbjct: 1 MEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEAN 60
Query: 486 IKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAI 307
IK++DFGF+ + + + +TFCGS YA+PE+ +G Y + D+WS+GV+LY +
Sbjct: 61 IKIADFGFSN-----EFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTL 115
Query: 306 VYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIPQILA 136
V G LPFD N +L ++V + K P +S +C ++ R +L P K R + QI+
Sbjct: 116 VSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFLVLNPAK-RCTLEQIMK 172
Query: 135 DPWLN 121
D W+N
Sbjct: 173 DKWIN 177
>AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 758
Score = 142 bits (343), Expect = 2e-33
Identities = 78/215 (36%), Positives = 124/215 (57%), Gaps = 3/215 (1%)
Frame = -1
Query: 705 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
LQ + R+ ++ + G + D + + E R F+Q+V AV YCH++ +VHRD
Sbjct: 101 LQKLFREVRIMKILNHPNIGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRD 160
Query: 525 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 346
+K ENLL+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y +
Sbjct: 161 LKAENLLLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPE 215
Query: 345 SDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA-- 175
DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L
Sbjct: 216 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLN 273
Query: 174 PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
P+K R + QI+ D W+N H+E +L+ + +
Sbjct: 274 PIK-RGSLEQIMKDRWMNVG----HEEEELKPYTE 303
>AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein.
Length = 870
Score = 142 bits (343), Expect = 2e-33
Identities = 78/215 (36%), Positives = 124/215 (57%), Gaps = 3/215 (1%)
Frame = -1
Query: 705 LQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRD 526
LQ + R+ ++ + G + D + + E R F+Q+V AV YCH++ +VHRD
Sbjct: 213 LQKLFREVRIMKILNHPNIGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRD 272
Query: 525 IKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQD 346
+K ENLL+D +NIK++DFGF+ + V +TFCGS YA+PE+ +G Y +
Sbjct: 273 LKAENLLLDGDMNIKIADFGFSN-----EFTVGNKLDTFCGSPPYAAPELFQGKKYDGPE 327
Query: 345 SDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA-- 175
DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L
Sbjct: 328 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLN 385
Query: 174 PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 70
P+K R + QI+ D W+N H+E +L+ + +
Sbjct: 386 PIK-RGSLEQIMKDRWMNVG----HEEEELKPYTE 415
>AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 603
Score = 141 bits (341), Expect = 3e-33
Identities = 66/181 (36%), Positives = 109/181 (60%)
Frame = -1
Query: 732 LKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYC 553
++H ++++ E +Y+V+E+ G L D + K + R++F+Q++ A+D+C
Sbjct: 2 IEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFC 61
Query: 552 HERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 373
H + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE++
Sbjct: 62 HSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPEVI 116
Query: 372 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKL 193
+G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F + +C+ L
Sbjct: 117 RGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQSL 175
Query: 192 I 190
+
Sbjct: 176 L 176
>AF542390-1|AAN62841.1| 258|Homo sapiens AT03158-like protein
protein.
Length = 258
Score = 139 bits (337), Expect = 9e-33
Identities = 71/149 (47%), Positives = 95/149 (63%), Gaps = 13/149 (8%)
Frame = -1
Query: 531 RDIKCENLLMDHGLNIKLSDFGFARGHMKPKN------------GVFA-LSETFCGSYAY 391
RD+K ENLL+D N+K+SDFGFA+ M P N F+ LS+T+CGS+AY
Sbjct: 77 RDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAY 134
Query: 390 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 211
A PEIL+G+PY P SD WSMGV+LY +V LPFDDTN +LL++ Q +V+FP +S
Sbjct: 135 ACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTIS 194
Query: 210 AECRKLITRILAPLKMRVKIPQILADPWL 124
EC+ LI ++L R I I+ D W+
Sbjct: 195 QECKNLILQMLRQATKRATILDIIKDSWV 223
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 136 bits (329), Expect = 8e-32
Identities = 72/184 (39%), Positives = 106/184 (57%), Gaps = 15/184 (8%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKD-------------- 619
REI+ +K +H ++I+ Q I T +++VMEY G L D I K+
Sbjct: 74 REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGS 133
Query: 618 -QHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKP 442
+ +DE RR F+Q++ VDYCH VVHRD+K EN+L+D +N K++DFG +
Sbjct: 134 TKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MM 190
Query: 441 KNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQL 262
+G F T CGS YA+PE++ G Y + D+WS GV+LYA++ G LPFDD + L
Sbjct: 191 SDGEFL--RTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTL 248
Query: 261 LKQV 250
K++
Sbjct: 249 FKKI 252
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 136 bits (329), Expect = 8e-32
Identities = 75/218 (34%), Positives = 117/218 (53%), Gaps = 2/218 (0%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
++ L REI ++ L H N+IR + +ET ++++VMEYA G L I + + E +
Sbjct: 115 QRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESK 174
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
F Q+V AV + HE ++HRD+K EN+ +K+ DFGF+ K + + T
Sbjct: 175 LIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGE-----MLNT 229
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVS 235
FCGS YA+PE+ + Y D+W++GV+LY +V G +PF +L K + + S
Sbjct: 230 FCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYS 289
Query: 234 FPREPKVSAECRKLITRILAPLKM-RVKIPQILADPWL 124
P P VS C +LI +L + R I I+ D W+
Sbjct: 290 VP--PHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWM 325
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 136 bits (328), Expect = 1e-31
Identities = 74/225 (32%), Positives = 130/225 (57%), Gaps = 3/225 (1%)
Frame = -1
Query: 774 LKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRG 595
L+ L REIE+ L+H N++R RVY+++EYA G L ++K + +DE R
Sbjct: 50 LEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRT 109
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSE 415
+++ +A+ YCH++ V+HRDIK ENLL+ +K++DFG++ P+ +
Sbjct: 110 ATIIEEVADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWSVHTPLPER------K 163
Query: 414 TFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKV 238
T CG+ Y PE+++G Y + D+W +GV+ Y ++ G PF+ ++++ +++ + V
Sbjct: 164 TMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDV 222
Query: 237 SFPREPKVSAECRKLITRIL--APLKMRVKIPQILADPWLNPNQQ 109
FP + A R LI+R+L PL+ R+ + QIL PW+ + +
Sbjct: 223 RFPLSMPLGA--RDLISRLLRYQPLE-RLPLAQILKHPWVQAHSR 264
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 134 bits (324), Expect = 3e-31
Identities = 75/225 (33%), Positives = 129/225 (57%), Gaps = 3/225 (1%)
Frame = -1
Query: 774 LKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRG 595
L+ L REIE+ L+H N++R RVY+++EYA G L ++K + +DE R
Sbjct: 50 LEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRT 109
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSE 415
++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++ H +
Sbjct: 110 ATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLR-----RK 163
Query: 414 TFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKV 238
T CG+ Y PE+++G Y + D+W +GV+ Y ++ G PF+ ++++ +++ + V
Sbjct: 164 TMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDV 222
Query: 237 SFPREPKVSAECRKLITRIL--APLKMRVKIPQILADPWLNPNQQ 109
FP + A R LI+R+L PL+ R+ + QIL PW+ + +
Sbjct: 223 RFPLSMPLGA--RDLISRLLRYQPLE-RLPLAQILKHPWVQAHSR 264
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 134 bits (324), Expect = 3e-31
Identities = 75/225 (33%), Positives = 129/225 (57%), Gaps = 3/225 (1%)
Frame = -1
Query: 774 LKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRG 595
L+ L REIE+ L+H N++R RVY+++EYA G L ++K + +DE R
Sbjct: 81 LEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRT 140
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSE 415
++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++ H +
Sbjct: 141 ATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLR-----RK 194
Query: 414 TFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKV 238
T CG+ Y PE+++G Y + D+W +GV+ Y ++ G PF+ ++++ +++ + V
Sbjct: 195 TMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDV 253
Query: 237 SFPREPKVSAECRKLITRIL--APLKMRVKIPQILADPWLNPNQQ 109
FP + A R LI+R+L PL+ R+ + QIL PW+ + +
Sbjct: 254 RFPLSMPLGA--RDLISRLLRYQPLE-RLPLAQILKHPWVQAHSR 295
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 134 bits (324), Expect = 3e-31
Identities = 75/225 (33%), Positives = 129/225 (57%), Gaps = 3/225 (1%)
Frame = -1
Query: 774 LKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRG 595
L+ L REIE+ L+H N++R RVY+++EYA G L ++K + +DE R
Sbjct: 65 LEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRT 124
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSE 415
++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++ H +
Sbjct: 125 ATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLR-----RK 178
Query: 414 TFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKV 238
T CG+ Y PE+++G Y + D+W +GV+ Y ++ G PF+ ++++ +++ + V
Sbjct: 179 TMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDV 237
Query: 237 SFPREPKVSAECRKLITRIL--APLKMRVKIPQILADPWLNPNQQ 109
FP + A R LI+R+L PL+ R+ + QIL PW+ + +
Sbjct: 238 RFPLSMPLGA--RDLISRLLRYQPLE-RLPLAQILKHPWVQAHSR 279
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 134 bits (324), Expect = 3e-31
Identities = 75/225 (33%), Positives = 129/225 (57%), Gaps = 3/225 (1%)
Frame = -1
Query: 774 LKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRG 595
L+ L REIE+ L+H N++R RVY+++EYA G L ++K + +DE R
Sbjct: 84 LEHQLRREIEIQAHLQHPNILRLYNHFHDARRVYLILEYAPRGELYKELQKSEKLDEQRT 143
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSE 415
++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++ H +
Sbjct: 144 ATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLR-----RK 197
Query: 414 TFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKV 238
T CG+ Y PE+++G Y + D+W +GV+ Y ++ G PF+ ++++ +++ + V
Sbjct: 198 TMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDV 256
Query: 237 SFPREPKVSAECRKLITRIL--APLKMRVKIPQILADPWLNPNQQ 109
FP + A R LI+R+L PL+ R+ + QIL PW+ + +
Sbjct: 257 RFPLSMPLGA--RDLISRLLRYQPLE-RLPLAQILKHPWVQAHSR 298
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 134 bits (324), Expect = 3e-31
Identities = 75/225 (33%), Positives = 129/225 (57%), Gaps = 3/225 (1%)
Frame = -1
Query: 774 LKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRG 595
L+ L REIE+ L+H N++R RVY+++EYA G L ++K + +DE R
Sbjct: 84 LEHQLRREIEIQAHLQHPNILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRT 143
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSE 415
++L +A+ YCH++ V+HRDIK ENLL+ +K++DFG++ H +
Sbjct: 144 ATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS-VHTPSLR-----RK 197
Query: 414 TFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKV 238
T CG+ Y PE+++G Y + D+W +GV+ Y ++ G PF+ ++++ +++ + V
Sbjct: 198 TMCGTLDYLPPEMIEGRTY-DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDV 256
Query: 237 SFPREPKVSAECRKLITRIL--APLKMRVKIPQILADPWLNPNQQ 109
FP + A R LI+R+L PL+ R+ + QIL PW+ + +
Sbjct: 257 RFPLSMPLGA--RDLISRLLRYQPLE-RLPLAQILKHPWVQAHSR 298
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 133 bits (321), Expect = 8e-31
Identities = 81/265 (30%), Positives = 139/265 (52%), Gaps = 13/265 (4%)
Frame = -1
Query: 768 KFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRR 589
K L RE+ ++K +KHE++I Q ET ++Y+VME E+G L +I+ + H E R
Sbjct: 158 KLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRW 217
Query: 588 WFKQLVEAVDYCHERGVVHRDIKCENLLM---------DHGLNIKLSDFGFARGHMKPKN 436
+ L A+ Y H +VHRD+K EN+++ + LNIK++DFG A +K ++
Sbjct: 218 IIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA---VKKQS 274
Query: 435 GVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK 256
A+ + CG+ Y +PE++ Y Q D+WS+GVV+Y ++ G PF ++ +L +
Sbjct: 275 RSEAMLQATCGTPIYMAPEVISAHDY-SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFE 333
Query: 255 QV-QNKVSFPREPKVS-AECRKLITRILAPL--KMRVKIPQILADPWLNPNQQSKHDETD 88
+ + ++ F S ++C K + + L + R+ ++L + WL N+ S T+
Sbjct: 334 LIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTN 393
Query: 87 LQEHAKTSKEEIKSVNIGTVTYDRK 13
+ E K K +SV T K
Sbjct: 394 VLEMMKEWKNNPESVEENTTEEKNK 418
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 133 bits (321), Expect = 8e-31
Identities = 81/265 (30%), Positives = 139/265 (52%), Gaps = 13/265 (4%)
Frame = -1
Query: 768 KFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRR 589
K L RE+ ++K +KHE++I Q ET ++Y+VME E+G L +I+ + H E R
Sbjct: 158 KLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRW 217
Query: 588 WFKQLVEAVDYCHERGVVHRDIKCENLLM---------DHGLNIKLSDFGFARGHMKPKN 436
+ L A+ Y H +VHRD+K EN+++ + LNIK++DFG A +K ++
Sbjct: 218 IIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA---VKKQS 274
Query: 435 GVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK 256
A+ + CG+ Y +PE++ Y Q D+WS+GVV+Y ++ G PF ++ +L +
Sbjct: 275 RSEAMLQATCGTPIYMAPEVISAHDY-SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFE 333
Query: 255 QV-QNKVSFPREPKVS-AECRKLITRILAPL--KMRVKIPQILADPWLNPNQQSKHDETD 88
+ + ++ F S ++C K + + L + R+ ++L + WL N+ S T+
Sbjct: 334 LIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTN 393
Query: 87 LQEHAKTSKEEIKSVNIGTVTYDRK 13
+ E K K +SV T K
Sbjct: 394 VLEMMKEWKNNPESVEENTTEEKNK 418
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 133 bits (321), Expect = 8e-31
Identities = 81/265 (30%), Positives = 139/265 (52%), Gaps = 13/265 (4%)
Frame = -1
Query: 768 KFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRR 589
K L RE+ ++K +KHE++I Q ET ++Y+VME E+G L +I+ + H E R
Sbjct: 158 KLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRW 217
Query: 588 WFKQLVEAVDYCHERGVVHRDIKCENLLM---------DHGLNIKLSDFGFARGHMKPKN 436
+ L A+ Y H +VHRD+K EN+++ + LNIK++DFG A +K ++
Sbjct: 218 IIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA---VKKQS 274
Query: 435 GVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK 256
A+ + CG+ Y +PE++ Y Q D+WS+GVV+Y ++ G PF ++ +L +
Sbjct: 275 RSEAMLQATCGTPIYMAPEVISAHDY-SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFE 333
Query: 255 QV-QNKVSFPREPKVS-AECRKLITRILAPL--KMRVKIPQILADPWLNPNQQSKHDETD 88
+ + ++ F S ++C K + + L + R+ ++L + WL N+ S T+
Sbjct: 334 LIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTN 393
Query: 87 LQEHAKTSKEEIKSVNIGTVTYDRK 13
+ E K K +SV T K
Sbjct: 394 VLEMMKEWKNNPESVEENTTEEKNK 418
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 130 bits (315), Expect = 4e-30
Identities = 78/217 (35%), Positives = 118/217 (54%), Gaps = 7/217 (3%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E+ V++ ++H N+I+ ++ ET RVY+VME A G L D I E R + +
Sbjct: 143 ELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMV 202
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDH-GLNIK--LSDFGFARGHMKPKNGVFALSETFCG 403
++ V Y H G+ HRD+K ENLL H G + K ++DFG A K G L +T CG
Sbjct: 203 LDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR---KKGDDCLMKTTCG 259
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR 226
+ Y +PE+L PY D+W++GV+ Y ++ G +PF+D N T+L +Q+ + K S+
Sbjct: 260 TPEYIAPEVLVRKPY-TNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSG 318
Query: 225 E--PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
E P VS + I R+L R+ Q L PW+
Sbjct: 319 EPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 130 bits (315), Expect = 4e-30
Identities = 78/217 (35%), Positives = 118/217 (54%), Gaps = 7/217 (3%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E+ V++ ++H N+I+ ++ ET RVY+VME A G L D I E R + +
Sbjct: 143 ELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMV 202
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDH-GLNIK--LSDFGFARGHMKPKNGVFALSETFCG 403
++ V Y H G+ HRD+K ENLL H G + K ++DFG A K G L +T CG
Sbjct: 203 LDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR---KKGDDCLMKTTCG 259
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR 226
+ Y +PE+L PY D+W++GV+ Y ++ G +PF+D N T+L +Q+ + K S+
Sbjct: 260 TPEYIAPEVLVRKPY-TNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSG 318
Query: 225 E--PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
E P VS + I R+L R+ Q L PW+
Sbjct: 319 EPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 130 bits (314), Expect = 5e-30
Identities = 71/234 (30%), Positives = 123/234 (52%), Gaps = 1/234 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE+E+ L+H N++R RVY+++EYA G++ ++K DE R +
Sbjct: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+L A+ YCH + V+HRDIK ENLL+ +K++DFG++ + + T CG
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCG 291
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F
Sbjct: 292 TLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFP 349
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 64
V+ R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 130 bits (314), Expect = 5e-30
Identities = 71/234 (30%), Positives = 123/234 (52%), Gaps = 1/234 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE+E+ L+H N++R RVY+++EYA G++ ++K DE R +
Sbjct: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+L A+ YCH + V+HRDIK ENLL+ +K++DFG++ + + T CG
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCG 291
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F
Sbjct: 292 TLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFP 349
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 64
V+ R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 130 bits (314), Expect = 5e-30
Identities = 71/234 (30%), Positives = 123/234 (52%), Gaps = 1/234 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE+E+ L+H N++R RVY+++EYA G++ ++K DE R +
Sbjct: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+L A+ YCH + V+HRDIK ENLL+ +K++DFG++ + + T CG
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCG 291
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F
Sbjct: 292 TLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFP 349
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 64
V+ R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 130 bits (314), Expect = 5e-30
Identities = 71/234 (30%), Positives = 123/234 (52%), Gaps = 1/234 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE+E+ L+H N++R RVY+++EYA G++ ++K DE R +
Sbjct: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+L A+ YCH + V+HRDIK ENLL+ +K++DFG++ + + T CG
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCG 291
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F
Sbjct: 292 TLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFP 349
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 64
V+ R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 130 bits (314), Expect = 5e-30
Identities = 71/234 (30%), Positives = 123/234 (52%), Gaps = 1/234 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE+E+ L+H N++R RVY+++EYA G++ ++K DE R +
Sbjct: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+L A+ YCH + V+HRDIK ENLL+ +K++DFG++ + + T CG
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCG 291
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F
Sbjct: 292 TLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFP 349
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 64
V+ R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 130 bits (314), Expect = 5e-30
Identities = 71/234 (30%), Positives = 123/234 (52%), Gaps = 1/234 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE+E+ L+H N++R RVY+++EYA G++ ++K DE R +
Sbjct: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+L A+ YCH + V+HRDIK ENLL+ +K++DFG++ + + T CG
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCG 291
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F
Sbjct: 292 TLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFP 349
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 64
V+ R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 130 bits (314), Expect = 5e-30
Identities = 71/234 (30%), Positives = 123/234 (52%), Gaps = 1/234 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE+E+ L+H N++R RVY+++EYA G++ ++K DE R +
Sbjct: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+L A+ YCH + V+HRDIK ENLL+ +K++DFG++ + + T CG
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCG 291
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F
Sbjct: 292 TLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFP 349
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 64
V+ R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 130 bits (314), Expect = 5e-30
Identities = 71/234 (30%), Positives = 123/234 (52%), Gaps = 1/234 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE+E+ L+H N++R RVY+++EYA G++ ++K DE R +
Sbjct: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+L A+ YCH + V+HRDIK ENLL+ +K++DFG++ + + T CG
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCG 291
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F
Sbjct: 292 TLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFP 349
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 64
V+ R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 350 DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 130 bits (313), Expect = 7e-30
Identities = 67/191 (35%), Positives = 115/191 (60%), Gaps = 4/191 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRK-DQHIDETRGRRWFK 580
+E+ +K ++H N++R + I+T ++Y+++E + G + D I K ++ ++E +++F
Sbjct: 62 QEVRCMKLVQHPNIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFA 121
Query: 579 QLVEAVDYCHERGVVHRDIKCENLLM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
Q+V A+ YCH+ VVHRD+K EN++ GL +KL+DFGF+ K T C
Sbjct: 122 QIVHAISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSC 175
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 229
GS AY++PEIL G Y D+WS+GV+L+ +V + PF + N ++ L + + K + P
Sbjct: 176 GSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCEQPPFQEANDSETLTMIMDCKYTVP 235
Query: 228 REPKVSAECRK 196
VS EC++
Sbjct: 236 SH--VSKECKE 244
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 129 bits (312), Expect = 1e-29
Identities = 70/234 (29%), Positives = 123/234 (52%), Gaps = 1/234 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE+E+ L+H N++R RVY+++EYA G++ ++K DE R +
Sbjct: 177 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTANLY 236
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
++ A+ YCH + V+HRDIK ENLL+ +K++DFG++ + + T CG
Sbjct: 237 NRIANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCG 290
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F
Sbjct: 291 TLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFP 348
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 64
V+ R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 349 DFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 402
>AB183428-1|BAF73616.1| 580|Homo sapiens maternal embryonic luecine
zipper kinase v3 protein.
Length = 580
Score = 128 bits (308), Expect = 3e-29
Identities = 70/182 (38%), Positives = 100/182 (54%), Gaps = 2/182 (1%)
Frame = -1
Query: 663 EYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNI 484
+Y G L D I + E R F+Q+V AV Y H +G HRD+K ENLL D +
Sbjct: 16 QYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKL 75
Query: 483 KLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIV 304
KL DFG KPK +T CGS AYA+PE+++G Y ++DVWSMG++LY ++
Sbjct: 76 KLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLM 132
Query: 303 YGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADP 130
G LPFDD N L K++ + K P+ +S L+ ++L K R+ + +L P
Sbjct: 133 CGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQMLQVDPKKRISMKNLLNHP 190
Query: 129 WL 124
W+
Sbjct: 191 WI 192
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 125 bits (302), Expect = 2e-28
Identities = 76/217 (35%), Positives = 113/217 (52%), Gaps = 3/217 (1%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ +EI + K L HEN+++F + Y+ +EY G L D I D + E +R+F
Sbjct: 52 IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFF 111
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A + N L CG
Sbjct: 112 HQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCG 169
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPR 226
+ Y +PE+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++
Sbjct: 170 TLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLN 229
Query: 225 E-PKVSAECRKLITRILAP-LKMRVKIPQILADPWLN 121
K+ + L+ +IL R+ IP I D W N
Sbjct: 230 PWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYN 266
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 125 bits (302), Expect = 2e-28
Identities = 76/217 (35%), Positives = 113/217 (52%), Gaps = 3/217 (1%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ +EI + K L HEN+++F + Y+ +EY G L D I D + E +R+F
Sbjct: 52 IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFF 111
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A + N L CG
Sbjct: 112 HQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCG 169
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPR 226
+ Y +PE+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++
Sbjct: 170 TLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLN 229
Query: 225 E-PKVSAECRKLITRILAP-LKMRVKIPQILADPWLN 121
K+ + L+ +IL R+ IP I D W N
Sbjct: 230 PWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYN 266
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 125 bits (302), Expect = 2e-28
Identities = 76/217 (35%), Positives = 113/217 (52%), Gaps = 3/217 (1%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ +EI + K L HEN+++F + Y+ +EY G L D I D + E +R+F
Sbjct: 52 IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFF 111
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A + N L CG
Sbjct: 112 HQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCG 169
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPR 226
+ Y +PE+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++
Sbjct: 170 TLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLN 229
Query: 225 E-PKVSAECRKLITRILAP-LKMRVKIPQILADPWLN 121
K+ + L+ +IL R+ IP I D W N
Sbjct: 230 PWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYN 266
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 125 bits (302), Expect = 2e-28
Identities = 76/217 (35%), Positives = 113/217 (52%), Gaps = 3/217 (1%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ +EI + K L HEN+++F + Y+ +EY G L D I D + E +R+F
Sbjct: 52 IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFF 111
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A + N L CG
Sbjct: 112 HQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCG 169
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPR 226
+ Y +PE+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++
Sbjct: 170 TLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLN 229
Query: 225 E-PKVSAECRKLITRILAP-LKMRVKIPQILADPWLN 121
K+ + L+ +IL R+ IP I D W N
Sbjct: 230 PWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYN 266
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 125 bits (302), Expect = 2e-28
Identities = 76/217 (35%), Positives = 113/217 (52%), Gaps = 3/217 (1%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ +EI + K L HEN+++F + Y+ +EY G L D I D + E +R+F
Sbjct: 52 IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFF 111
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A + N L CG
Sbjct: 112 HQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCG 169
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPR 226
+ Y +PE+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++
Sbjct: 170 TLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLN 229
Query: 225 E-PKVSAECRKLITRILAP-LKMRVKIPQILADPWLN 121
K+ + L+ +IL R+ IP I D W N
Sbjct: 230 PWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYN 266
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 125 bits (302), Expect = 2e-28
Identities = 76/217 (35%), Positives = 113/217 (52%), Gaps = 3/217 (1%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ +EI + K L HEN+++F + Y+ +EY G L D I D + E +R+F
Sbjct: 52 IKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFF 111
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
QL+ V Y H G+ HRDIK ENLL+D N+K+SDFG A + N L CG
Sbjct: 112 HQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCG 169
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPR 226
+ Y +PE+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++
Sbjct: 170 TLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLN 229
Query: 225 E-PKVSAECRKLITRILAP-LKMRVKIPQILADPWLN 121
K+ + L+ +IL R+ IP I D W N
Sbjct: 230 PWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYN 266
>BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein.
Length = 1102
Score = 122 bits (295), Expect = 1e-27
Identities = 71/164 (43%), Positives = 95/164 (57%), Gaps = 3/164 (1%)
Frame = -1
Query: 606 ETRGRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVF 427
E RR FKQ+V AV +CH R +VHRD+K ENLL+D LNIK++DFGF+ +
Sbjct: 3 EKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ---- 58
Query: 426 ALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV- 250
L +T+CGS YA+PE+ +G Y D+WS+GVVLY +V G LPFD + L +V
Sbjct: 59 -LLKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVL 117
Query: 249 QNKVSFPREPKVSAECRKLITR--ILAPLKMRVKIPQILADPWL 124
K P +S EC LI +L P K R+ + QI W+
Sbjct: 118 SGKFRIPF--FMSTECEHLIRHMLVLDPNK-RLSMEQICKHKWM 158
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 120 bits (290), Expect = 4e-27
Identities = 69/231 (29%), Positives = 120/231 (51%), Gaps = 1/231 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L REIE+ L H N++R R+Y+++EYA G L ++K DE R
Sbjct: 122 LRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIM 181
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++ + +T CG
Sbjct: 182 EELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS------VHAPSLRRKTMCG 235
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + + D+W +GV+ Y ++ G PF+ ++ + +++ KV
Sbjct: 236 TLDYLPPEMIEGRMHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIV-KVDLKFP 293
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
V + LI+++L R+ + Q+ A PW+ N + + LQ A
Sbjct: 294 ASVPTGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA 344
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 120 bits (290), Expect = 4e-27
Identities = 69/231 (29%), Positives = 120/231 (51%), Gaps = 1/231 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L REIE+ L H N++R R+Y+++EYA G L ++K DE R
Sbjct: 122 LRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIM 181
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++ + +T CG
Sbjct: 182 EELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS------VHAPSLRRKTMCG 235
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + + D+W +GV+ Y ++ G PF+ ++ + +++ KV
Sbjct: 236 TLDYLPPEMIEGRMHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIV-KVDLKFP 293
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
V + LI+++L R+ + Q+ A PW+ N + + LQ A
Sbjct: 294 ASVPTGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA 344
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 120 bits (290), Expect = 4e-27
Identities = 69/231 (29%), Positives = 120/231 (51%), Gaps = 1/231 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L REIE+ L H N++R R+Y+++EYA G L ++K DE R
Sbjct: 122 LRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIM 181
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++ + +T CG
Sbjct: 182 EELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS------VHAPSLRRKTMCG 235
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + + D+W +GV+ Y ++ G PF+ ++ + +++ KV
Sbjct: 236 TLDYLPPEMIEGRMHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIV-KVDLKFP 293
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
V + LI+++L R+ + Q+ A PW+ N + + LQ A
Sbjct: 294 ASVPTGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA 344
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 120 bits (290), Expect = 4e-27
Identities = 69/231 (29%), Positives = 120/231 (51%), Gaps = 1/231 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L REIE+ L H N++R R+Y+++EYA G L ++K DE R
Sbjct: 122 LRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIM 181
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++ + +T CG
Sbjct: 182 EELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS------VHAPSLRRKTMCG 235
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + + D+W +GV+ Y ++ G PF+ ++ + +++ KV
Sbjct: 236 TLDYLPPEMIEGRMHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIV-KVDLKFP 293
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
V + LI+++L R+ + Q+ A PW+ N + + LQ A
Sbjct: 294 ASVPTGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA 344
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 120 bits (290), Expect = 4e-27
Identities = 69/231 (29%), Positives = 120/231 (51%), Gaps = 1/231 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L REIE+ L H N++R R+Y+++EYA G L ++K DE R
Sbjct: 122 LRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIM 181
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++ + +T CG
Sbjct: 182 EELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS------VHAPSLRRKTMCG 235
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + + D+W +GV+ Y ++ G PF+ ++ + +++ KV
Sbjct: 236 TLDYLPPEMIEGRMHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIV-KVDLKFP 293
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
V + LI+++L R+ + Q+ A PW+ N + + LQ A
Sbjct: 294 ASVPTGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA 344
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 120 bits (289), Expect = 6e-27
Identities = 71/220 (32%), Positives = 117/220 (53%), Gaps = 4/220 (1%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHI--DETR 598
K+ +E+ +++ +KH N++ F + + R++IVMEY + G L+ I + + + E +
Sbjct: 45 KEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQ 104
Query: 597 GRRWFKQLVEAVDYCHERGVVHRDIKCENL-LMDHGLNIKLSDFGFARGHMKPKNGVFAL 421
WF Q+ + + H+R ++HRDIK +N+ L +G+ KL DFG AR N L
Sbjct: 105 ILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGMVAKLGDFGIAR----VLNNSMEL 160
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK 241
+ T G+ Y SPEI + PY +D+WS+G VLY + + PF+ N QL+ ++
Sbjct: 161 ARTCIGTPYYLSPEICQNKPYN-NKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQA 219
Query: 240 VSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P P S E LI+++ + R I IL P+L
Sbjct: 220 HFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFL 259
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 120 bits (289), Expect = 6e-27
Identities = 69/231 (29%), Positives = 120/231 (51%), Gaps = 1/231 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L REIE+ L H N++R R+Y+++EYA G L ++K DE R
Sbjct: 149 LRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIM 208
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++ + +T CG
Sbjct: 209 EELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS------VHAPSLRRKTMCG 262
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + + D+W +GV+ Y ++ G PF+ ++ + +++ KV
Sbjct: 263 TLDYLPPEMIEGRMHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIV-KVDLKFP 320
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
V + LI+++L R+ + Q+ A PW+ N + + LQ A
Sbjct: 321 ASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA 371
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 120 bits (289), Expect = 6e-27
Identities = 69/231 (29%), Positives = 120/231 (51%), Gaps = 1/231 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L REIE+ L H N++R R+Y+++EYA G L ++K DE R
Sbjct: 122 LRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIM 181
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++ + +T CG
Sbjct: 182 EELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS------VHAPSLRRKTMCG 235
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + + D+W +GV+ Y ++ G PF+ ++ + +++ KV
Sbjct: 236 TLDYLPPEMIEGRMHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIV-KVDLKFP 293
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
V + LI+++L R+ + Q+ A PW+ N + + LQ A
Sbjct: 294 ASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA 344
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 120 bits (289), Expect = 6e-27
Identities = 71/220 (32%), Positives = 117/220 (53%), Gaps = 4/220 (1%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHI--DETR 598
K+ +E+ +++ +KH N++ F + + R++IVMEY + G L+ I + + + E +
Sbjct: 45 KEASKKEVILLEKMKHPNIVAFFNSFQENGRLFIVMEYCDGGDLMKRINRQRGVLFSEDQ 104
Query: 597 GRRWFKQLVEAVDYCHERGVVHRDIKCENL-LMDHGLNIKLSDFGFARGHMKPKNGVFAL 421
WF Q+ + + H+R ++HRDIK +N+ L +G+ KL DFG AR N L
Sbjct: 105 ILGWFVQISLGLKHIHDRKILHRDIKAQNIFLSKNGMVAKLGDFGIAR----VLNNSMEL 160
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK 241
+ T G+ Y SPEI + PY +D+WS+G VLY + + PF+ N QL+ ++
Sbjct: 161 ARTCIGTPYYLSPEICQNKPYN-NKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQA 219
Query: 240 VSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P P S E LI+++ + R I IL P+L
Sbjct: 220 HFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFL 259
>BC043487-1|AAH43487.1| 505|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 1,
alpha protein.
Length = 505
Score = 120 bits (288), Expect = 8e-27
Identities = 69/244 (28%), Positives = 133/244 (54%), Gaps = 7/244 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIE--TTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ +Y+V + G ++++ D+ E + R +
Sbjct: 198 QEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEV-PCDKPFSEEQARLYL 256
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ ++ ++Y H + +VHRDIK NLL+ ++K++DFG + G A + G
Sbjct: 257 RDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF----EGNDAQLSSTAG 312
Query: 402 SYAYASPEIL--KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE + G + + DVW+ GV LY VYG+ PF D L ++++N+ V F
Sbjct: 313 TPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVF 372
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWLNPN-QQSKHDETDLQEHAKTSKE 58
P EP++S E + LI ++L + R+ +P I PW+ N ++ E + + ++E
Sbjct: 373 PEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEE 432
Query: 57 EIKS 46
E+K+
Sbjct: 433 EVKN 436
>AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein
protein.
Length = 505
Score = 120 bits (288), Expect = 8e-27
Identities = 69/244 (28%), Positives = 133/244 (54%), Gaps = 7/244 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIE--TTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ +Y+V + G ++++ D+ E + R +
Sbjct: 198 QEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEV-PCDKPFSEEQARLYL 256
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ ++ ++Y H + +VHRDIK NLL+ ++K++DFG + G A + G
Sbjct: 257 RDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF----EGNDAQLSSTAG 312
Query: 402 SYAYASPEIL--KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE + G + + DVW+ GV LY VYG+ PF D L ++++N+ V F
Sbjct: 313 TPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVF 372
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWLNPN-QQSKHDETDLQEHAKTSKE 58
P EP++S E + LI ++L + R+ +P I PW+ N ++ E + + ++E
Sbjct: 373 PEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEE 432
Query: 57 EIKS 46
E+K+
Sbjct: 433 EVKN 436
>AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein
protein.
Length = 505
Score = 120 bits (288), Expect = 8e-27
Identities = 69/244 (28%), Positives = 133/244 (54%), Gaps = 7/244 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIE--TTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ +Y+V + G ++++ D+ E + R +
Sbjct: 198 QEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEV-PCDKPFSEEQARLYL 256
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ ++ ++Y H + +VHRDIK NLL+ ++K++DFG + G A + G
Sbjct: 257 RDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF----EGNDAQLSSTAG 312
Query: 402 SYAYASPEIL--KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE + G + + DVW+ GV LY VYG+ PF D L ++++N+ V F
Sbjct: 313 TPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVF 372
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWLNPN-QQSKHDETDLQEHAKTSKE 58
P EP++S E + LI ++L + R+ +P I PW+ N ++ E + + ++E
Sbjct: 373 PEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEE 432
Query: 57 EIKS 46
E+K+
Sbjct: 433 EVKN 436
>AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta protein.
Length = 588
Score = 120 bits (288), Expect = 8e-27
Identities = 64/217 (29%), Positives = 124/217 (57%), Gaps = 6/217 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL + G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNYVG 349
Query: 402 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKAKDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 119 bits (287), Expect = 1e-26
Identities = 74/215 (34%), Positives = 114/215 (53%), Gaps = 2/215 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L REIE+++GL+H N++ L + ET V +V +YAE G L I+ D + E + +
Sbjct: 48 LQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIA 106
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
QLV A+ Y H ++HRD+K +N+L+ G IKL DFGFAR M V + G
Sbjct: 107 AQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARA-MSTNTMVLT---SIKG 162
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y SPE+++ PY +D+WS+G +LY + G PF T+ QL+ + R
Sbjct: 163 TPLYMSPELVEERPY-DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDP--VRW 219
Query: 222 PKVSAECRK--LITRILAPLKMRVKIPQILADPWL 124
P + C K L + + R+ P +L P++
Sbjct: 220 PSTISPCFKDFLQGLLTKDPRQRLSWPDLLYHPFI 254
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 119 bits (287), Expect = 1e-26
Identities = 74/215 (34%), Positives = 114/215 (53%), Gaps = 2/215 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L REIE+++GL+H N++ L + ET V +V +YAE G L I+ D + E + +
Sbjct: 48 LQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIA 106
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
QLV A+ Y H ++HRD+K +N+L+ G IKL DFGFAR M V + G
Sbjct: 107 AQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARA-MSTNTMVLT---SIKG 162
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y SPE+++ PY +D+WS+G +LY + G PF T+ QL+ + R
Sbjct: 163 TPLYMSPELVEERPY-DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDP--VRW 219
Query: 222 PKVSAECRK--LITRILAPLKMRVKIPQILADPWL 124
P + C K L + + R+ P +L P++
Sbjct: 220 PSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFI 254
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 119 bits (287), Expect = 1e-26
Identities = 74/215 (34%), Positives = 114/215 (53%), Gaps = 2/215 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L REIE+++GL+H N++ L + ET V +V +YAE G L I+ D + E + +
Sbjct: 65 LQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAE-GELFQILEDDGKLPEDQVQAIA 123
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
QLV A+ Y H ++HRD+K +N+L+ G IKL DFGFAR M V + G
Sbjct: 124 AQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARA-MSTNTMVLT---SIKG 179
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y SPE+++ PY +D+WS+G +LY + G PF T+ QL+ + R
Sbjct: 180 TPLYMSPELVEERPY-DHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDP--VRW 236
Query: 222 PKVSAECRK--LITRILAPLKMRVKIPQILADPWL 124
P + C K L + + R+ P +L P++
Sbjct: 237 PSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFI 271
>U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kinase
homolog protein.
Length = 174
Score = 118 bits (285), Expect = 2e-26
Identities = 58/141 (41%), Positives = 85/141 (60%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI+ +K +H ++I+ Q I T +++VMEY G L D I K+ +DE RR F+Q
Sbjct: 39 REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQ 98
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ VDYCH VVHRD+K EN+L+D +N K++DFG + +G F T CGS
Sbjct: 99 ILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSP 153
Query: 396 AYASPEILKGVPYRPQDSDVW 334
YA+PE++ G Y + D+W
Sbjct: 154 NYAAPEVISGRLYVGPEVDLW 174
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 118 bits (285), Expect = 2e-26
Identities = 67/193 (34%), Positives = 112/193 (58%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V++ +H L A +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 200 ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEI 259
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A++Y H R VV+RDIK ENL++D +IK++DFG + + +G A +TFCG+
Sbjct: 260 VSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFCGTPE 315
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 316 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR--T 372
Query: 216 VSAECRKLITRIL 178
+S E + L+ +L
Sbjct: 373 LSPEAKSLLAGLL 385
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 118 bits (285), Expect = 2e-26
Identities = 67/193 (34%), Positives = 112/193 (58%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V++ +H L A +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 200 ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEI 259
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A++Y H R VV+RDIK ENL++D +IK++DFG + + +G A +TFCG+
Sbjct: 260 VSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFCGTPE 315
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 316 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR--T 372
Query: 216 VSAECRKLITRIL 178
+S E + L+ +L
Sbjct: 373 LSPEAKSLLAGLL 385
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 118 bits (285), Expect = 2e-26
Identities = 67/193 (34%), Positives = 112/193 (58%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V++ +H L A +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 200 ESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEI 259
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A++Y H R VV+RDIK ENL++D +IK++DFG + + +G A +TFCG+
Sbjct: 260 VSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFCGTPE 315
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 316 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPR--T 372
Query: 216 VSAECRKLITRIL 178
+S E + L+ +L
Sbjct: 373 LSPEAKSLLAGLL 385
>AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens
cDNA FLJ16039 fis, clone ADRGL2001554, weakly similar
to SERINE/THREONINE-PROTEIN KINASE PLK (EC 2.7.1.-). ).
Length = 706
Score = 118 bits (284), Expect = 2e-26
Identities = 64/222 (28%), Positives = 122/222 (54%), Gaps = 5/222 (2%)
Frame = -1
Query: 777 YLKKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETR 598
YL+KF+ EI + + L H ++ + + E Y+++E N +L ++R + + E
Sbjct: 80 YLEKFMS-EIRIHQSLDHPHICKMYKHFEDNRYHYLILELCSNETLAHLLRVRECLTEPE 138
Query: 597 GRRWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALS 418
+ + Q+++AV Y H+R ++HRD+K N+ +D L +K+ D G A +P
Sbjct: 139 VQYFLLQIIDAVSYLHKRCIIHRDLKLGNIFLDENLEVKVGDLGLAAQLNEPNE----RK 194
Query: 417 ETFCGSYAYASPEILKGVPYR--PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-Q 247
+T CG+ Y +PEIL+ R + D+W++GV+ Y ++ G+ PFD + +++ +
Sbjct: 195 KTMCGTPNYIAPEILQSNDKRAYSYEVDIWAVGVITYTMLIGKAPFDGGSKEITYRKIRE 254
Query: 246 NKVSFP-REPKVSAECRKLITRILAP-LKMRVKIPQILADPW 127
N++SFP ++ +S + R I IL P R+ + Q++ P+
Sbjct: 255 NELSFPIKDHHISHQARMFIRSILNPDPTQRLTLEQMVQHPF 296
>AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein.
Length = 347
Score = 118 bits (284), Expect = 2e-26
Identities = 71/234 (30%), Positives = 121/234 (51%), Gaps = 4/234 (1%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRG---R 592
L REIE+ L H N++R R+Y+++EYA G L + K DE R R
Sbjct: 122 LRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGMLYKELHKTCTFDEQRTATVR 181
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
R ++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++ + +T
Sbjct: 182 RIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS------VHAPSLRRKT 235
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSF 232
CG+ Y PE+++G + + D+W +GV+ Y ++ G PF+ ++ + +++ KV
Sbjct: 236 MCGTLDYLPPEMIEGRMHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIV-KVDL 293
Query: 231 PREPKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
V + LI+++L R+ + Q+ A PW+ N + + LQ A
Sbjct: 294 KFPASVPTGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA 347
>BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing
serine/threonine kinase protein.
Length = 1323
Score = 118 bits (283), Expect = 3e-26
Identities = 71/212 (33%), Positives = 114/212 (53%), Gaps = 2/212 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 577
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 1052 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 1111
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
LV AV Y + ++HRDIK EN+++ IKL DFG A + K L TFCG+
Sbjct: 1112 LVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 1166
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
Y +PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P
Sbjct: 1167 EYCAPEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--L 1219
Query: 216 VSAECRKLITRILAPL-KMRVKIPQILADPWL 124
VS E L++ +L P+ + R + +++ DPW+
Sbjct: 1220 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
>BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein.
Length = 953
Score = 118 bits (283), Expect = 3e-26
Identities = 71/212 (33%), Positives = 114/212 (53%), Gaps = 2/212 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 577
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 682 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 741
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
LV AV Y + ++HRDIK EN+++ IKL DFG A + K L TFCG+
Sbjct: 742 LVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 796
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
Y +PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P
Sbjct: 797 EYCAPEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--L 849
Query: 216 VSAECRKLITRILAPL-KMRVKIPQILADPWL 124
VS E L++ +L P+ + R + +++ DPW+
Sbjct: 850 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 881
>BC040457-1|AAH40457.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II alpha protein.
Length = 478
Score = 118 bits (283), Expect = 3e-26
Identities = 74/222 (33%), Positives = 116/222 (52%), Gaps = 8/222 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y++ + G L + I ++ E
Sbjct: 57 LEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCI 116
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 117 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFG---- 172
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G PF D + +L KQ++
Sbjct: 173 FAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYKQIKAGAYD 231
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWLN 121
FP V+ E + LI ++L P K R+ + L PW++
Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSK-RITAAEALKHPWIS 272
>AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein.
Length = 1323
Score = 118 bits (283), Expect = 3e-26
Identities = 71/212 (33%), Positives = 114/212 (53%), Gaps = 2/212 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 577
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 1052 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 1111
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
LV AV Y + ++HRDIK EN+++ IKL DFG A + K L TFCG+
Sbjct: 1112 LVSAVGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 1166
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
Y +PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P
Sbjct: 1167 EYCAPEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--L 1219
Query: 216 VSAECRKLITRILAPL-KMRVKIPQILADPWL 124
VS E L++ +L P+ + R + +++ DPW+
Sbjct: 1220 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
>BC026060-1|AAH26060.1| 541|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 2,
beta protein.
Length = 541
Score = 117 bits (281), Expect = 5e-26
Identities = 64/217 (29%), Positives = 123/217 (56%), Gaps = 6/217 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 402 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 117 bits (281), Expect = 5e-26
Identities = 74/221 (33%), Positives = 115/221 (52%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKDLINKMLTINPAK-RITASEALKHPWI 272
>AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 1 protein.
Length = 588
Score = 117 bits (281), Expect = 5e-26
Identities = 64/217 (29%), Positives = 123/217 (56%), Gaps = 6/217 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 402 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 2 protein.
Length = 533
Score = 117 bits (281), Expect = 5e-26
Identities = 64/217 (29%), Positives = 123/217 (56%), Gaps = 6/217 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 402 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 541
Score = 117 bits (281), Expect = 5e-26
Identities = 64/217 (29%), Positives = 123/217 (56%), Gaps = 6/217 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 402 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF287631-1|AAK64601.1| 533|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase b2
protein.
Length = 533
Score = 117 bits (281), Expect = 5e-26
Identities = 64/217 (29%), Positives = 123/217 (56%), Gaps = 6/217 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 402 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF287630-1|AAK64600.1| 588|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase b1
protein.
Length = 588
Score = 117 bits (281), Expect = 5e-26
Identities = 64/217 (29%), Positives = 123/217 (56%), Gaps = 6/217 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 402 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-dependent
kinase kinase protein.
Length = 417
Score = 117 bits (281), Expect = 5e-26
Identities = 64/217 (29%), Positives = 123/217 (56%), Gaps = 6/217 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 119 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 177
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 178 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 233
Query: 402 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 234 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 293
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 294 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 330
>AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta-3 protein.
Length = 541
Score = 117 bits (281), Expect = 5e-26
Identities = 64/217 (29%), Positives = 123/217 (56%), Gaps = 6/217 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 235 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 293
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 294 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 349
Query: 402 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 350 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 409
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 410 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein.
Length = 557
Score = 117 bits (281), Expect = 5e-26
Identities = 64/217 (29%), Positives = 123/217 (56%), Gaps = 6/217 (2%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHR--VYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+EI ++K L H N+++ ++ ++ + +Y+V E G ++++ + + E + R +F
Sbjct: 236 QEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTL-KPLSEDQARFYF 294
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ L++ ++Y H + ++HRDIK NLL+ +IK++DFG + G AL G
Sbjct: 295 QDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVG 350
Query: 402 SYAYASPEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSF 232
+ A+ +PE L + + DVW+MGV LY V+G+ PF D L +++++ + F
Sbjct: 351 TPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEF 410
Query: 231 PREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
P +P ++ + + LITR+L + R+ +P+I PW+
Sbjct: 411 PDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWV 447
>AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase
protein.
Length = 347
Score = 116 bits (280), Expect = 7e-26
Identities = 70/234 (29%), Positives = 121/234 (51%), Gaps = 4/234 (1%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRG---R 592
L REIE+ L H N++R R+Y+++EYA G L ++K DE R R
Sbjct: 122 LRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGMLYKELQKSCTFDEQRTATVR 181
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++ + +T
Sbjct: 182 AVMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS------VHAPSLRRKT 235
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSF 232
CG+ Y PE+++G + + D+W +GV+ Y ++ G PF+ ++ + +++ KV
Sbjct: 236 MCGTLDYLPPEMIEGRMHN-EKVDLWCIGVLCYELLVGNPPFESASHNETYRRIV-KVDL 293
Query: 231 PREPKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
V + LI+++L R+ + Q+ A PW+ N + + LQ A
Sbjct: 294 KFPASVPTGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA 347
>AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein.
Length = 343
Score = 116 bits (280), Expect = 7e-26
Identities = 69/231 (29%), Positives = 119/231 (51%), Gaps = 1/231 (0%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L REIE+ L H N++R R+Y+++EYA G L ++K DE R
Sbjct: 122 LRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIM 181
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
++L +A+ YCH + V+HRDIK ENLL+ +K++DFG++ + +T CG
Sbjct: 182 EELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS------VHATSLRRKTMCG 235
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPRE 223
+ Y PE+++G + D+W +GV+ Y ++ G PF+ ++ + +++ KV
Sbjct: 236 TLDYLPPEMIEG-RIDNEKVDLWCIGVLCYELLVGN-PFESASHNETYRRIV-KVDLKFP 292
Query: 222 PKVSAECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
V + LI+++L R+ + Q+ A PW+ N + + LQ A
Sbjct: 293 ASVPTGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA 343
>U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein
kinase protein.
Length = 458
Score = 116 bits (279), Expect = 1e-25
Identities = 70/212 (33%), Positives = 113/212 (53%), Gaps = 2/212 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENG-SLLDIIRKDQHIDETRGRRWFKQ 577
EI ++ ++H N+I+ L E +VME +G L I + +DE F+Q
Sbjct: 187 EIAILSRVEHANIIKVLDIFENQGFFQLVMEKHGSGLDLFAFIDRHPRLDEPLASYIFRQ 246
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
LV AV Y + ++HRD K EN+++ IKL DFG A + K L TFCG+
Sbjct: 247 LVSAVGYLRLKDIIHRDFKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTI 301
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK 217
Y +PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P
Sbjct: 302 EYCAPEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--L 354
Query: 216 VSAECRKLITRILAPL-KMRVKIPQILADPWL 124
VS E L++ +L P+ + R + +++ DPW+
Sbjct: 355 VSKELMSLVSGLLQPVPERRTTLEKLVTDPWV 386
>AF145711-1|AAD30559.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha-B
subunit protein.
Length = 489
Score = 116 bits (279), Expect = 1e-25
Identities = 73/222 (32%), Positives = 116/222 (52%), Gaps = 8/222 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y++ + G L + I ++ E
Sbjct: 57 LEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCI 116
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 117 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFG---- 172
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 173 FAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYD 231
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWLN 121
FP V+ E + LI ++L P K R+ + L PW++
Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSK-RITAAEALKHPWIS 272
>AF145710-1|AAD30558.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase II alpha
subunit protein.
Length = 478
Score = 116 bits (279), Expect = 1e-25
Identities = 73/222 (32%), Positives = 116/222 (52%), Gaps = 8/222 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y++ + G L + I ++ E
Sbjct: 57 LEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCI 116
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 117 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFG---- 172
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 173 FAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYD 231
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWLN 121
FP V+ E + LI ++L P K R+ + L PW++
Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSK-RITAAEALKHPWIS 272
>AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent
protein kinase II alpha protein.
Length = 478
Score = 116 bits (279), Expect = 1e-25
Identities = 73/222 (32%), Positives = 116/222 (52%), Gaps = 8/222 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y++ + G L + I ++ E
Sbjct: 57 LEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCI 116
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 117 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFG---- 172
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 173 FAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYD 231
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWLN 121
FP V+ E + LI ++L P K R+ + L PW++
Sbjct: 232 FPSPEWDTVTPEAKDLINKMLTINPSK-RITAAEALKHPWIS 272
>AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein.
Length = 527
Score = 116 bits (279), Expect = 1e-25
Identities = 73/222 (32%), Positives = 116/222 (52%), Gaps = 8/222 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y++ + G L + I ++ E
Sbjct: 106 LEREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCI 165
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 166 QQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFG---- 221
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 222 FAGTPGYLSPEVLRKDPY-GKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYD 280
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWLN 121
FP V+ E + LI ++L P K R+ + L PW++
Sbjct: 281 FPSPEWDTVTPEAKDLINKMLTINPSK-RITAAEALKHPWIS 321
>X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B
protein.
Length = 417
Score = 116 bits (278), Expect = 1e-25
Identities = 67/194 (34%), Positives = 114/194 (58%), Gaps = 2/194 (1%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V + +H L R + +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 135 ENRVQQNSRHPFLTRLKYSFQTHDRLCFVMEYANGGELFFHLSRERVFAEDRARFYGAEI 194
Query: 573 VEAVDYCH-ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
V A+DY H E+ VV+RD+K ENL++D +IK++DFG + + K+G A +TFCG+
Sbjct: 195 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTP 250
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 251 EYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-- 307
Query: 219 KVSAECRKLITRIL 178
+ E + L++ +L
Sbjct: 308 TLGPEAKSLLSGLL 321
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 116 bits (278), Expect = 1e-25
Identities = 59/167 (35%), Positives = 100/167 (59%), Gaps = 1/167 (0%)
Frame = -1
Query: 726 HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHE 547
H L + +T R++ VME+ G L+ I+K + DE R R + +++ A+ + H+
Sbjct: 412 HPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHD 471
Query: 546 RGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKG 367
+G+++RD+K +N+L+DH + KL+DFG + + NGV + TFCG+ Y +PEIL+
Sbjct: 472 KGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI--CNGV--TTATFCGTPDYIAPEILQE 527
Query: 366 VPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 229
+ Y P D W+MGV+LY ++ G PF+ N L + + N +V +P
Sbjct: 528 MLYGPA-VDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYP 573
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 116 bits (278), Expect = 1e-25
Identities = 59/167 (35%), Positives = 100/167 (59%), Gaps = 1/167 (0%)
Frame = -1
Query: 726 HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHE 547
H L + +T R++ VME+ G L+ I+K + DE R R + +++ A+ + H+
Sbjct: 413 HPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLHD 472
Query: 546 RGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKG 367
+G+++RD+K +N+L+DH + KL+DFG + + NGV + TFCG+ Y +PEIL+
Sbjct: 473 KGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI--CNGV--TTATFCGTPDYIAPEILQE 528
Query: 366 VPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 229
+ Y P D W+MGV+LY ++ G PF+ N L + + N +V +P
Sbjct: 529 MLYGPA-VDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYP 574
>BC032784-1|AAH32784.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II delta protein.
Length = 478
Score = 116 bits (278), Expect = 1e-25
Identities = 72/221 (32%), Positives = 115/221 (52%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++E+V++CH G+VHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKDLINKMLTINPAK-RITASEALKHPWI 272
>AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional
calcium/calmodulin-dependent protein kinase II delta2
isoform protein.
Length = 499
Score = 116 bits (278), Expect = 1e-25
Identities = 72/221 (32%), Positives = 115/221 (52%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++E+V++CH G+VHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKDLINKMLTINPAK-RITASEALKHPWI 272
>AB209288-1|BAD92525.1| 522|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
isoform 1 variant protein.
Length = 522
Score = 116 bits (278), Expect = 1e-25
Identities = 72/221 (32%), Positives = 115/221 (52%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 88 LEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 147
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++E+V++CH G+VHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 148 QQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG---- 203
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 204 FAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYD 262
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 263 FPSPEWDTVTPEAKDLINKMLTINPAK-RITASEALKHPWI 302
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 115 bits (277), Expect = 2e-25
Identities = 66/194 (34%), Positives = 114/194 (58%), Gaps = 2/194 (1%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V++ +H L + +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
Query: 573 VEAVDYCH-ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
V A+DY H E+ VV+RD+K ENL++D +IK++DFG + + K+G A +TFCG+
Sbjct: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTP 313
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 314 EYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-- 370
Query: 219 KVSAECRKLITRIL 178
+ E + L++ +L
Sbjct: 371 TLGPEAKSLLSGLL 384
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 115 bits (277), Expect = 2e-25
Identities = 66/194 (34%), Positives = 114/194 (58%), Gaps = 2/194 (1%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V++ +H L + +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
Query: 573 VEAVDYCH-ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
V A+DY H E+ VV+RD+K ENL++D +IK++DFG + + K+G A +TFCG+
Sbjct: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTP 313
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 314 EYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-- 370
Query: 219 KVSAECRKLITRIL 178
+ E + L++ +L
Sbjct: 371 TLGPEAKSLLSGLL 384
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 115 bits (277), Expect = 2e-25
Identities = 66/194 (34%), Positives = 114/194 (58%), Gaps = 2/194 (1%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V++ +H L + +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
Query: 573 VEAVDYCH-ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
V A+DY H E+ VV+RD+K ENL++D +IK++DFG + + K+G A +TFCG+
Sbjct: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTP 313
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 314 EYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-- 370
Query: 219 KVSAECRKLITRIL 178
+ E + L++ +L
Sbjct: 371 TLGPEAKSLLSGLL 384
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 115 bits (277), Expect = 2e-25
Identities = 66/194 (34%), Positives = 114/194 (58%), Gaps = 2/194 (1%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V++ +H L + +T R+ VMEYA G L + +++ E R R + ++
Sbjct: 198 ENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEI 257
Query: 573 VEAVDYCH-ERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
V A+DY H E+ VV+RD+K ENL++D +IK++DFG + + K+G A +TFCG+
Sbjct: 258 VSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTP 313
Query: 396 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREP 220
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR
Sbjct: 314 EYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR-- 370
Query: 219 KVSAECRKLITRIL 178
+ E + L++ +L
Sbjct: 371 TLGPEAKSLLSGLL 384
>AY987011-1|AAX88806.1| 489|Homo sapiens
calcium/calmodulin-dependent protein kinase II delta
protein.
Length = 489
Score = 115 bits (276), Expect = 2e-25
Identities = 72/220 (32%), Positives = 114/220 (51%), Gaps = 8/220 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++E+V++CH G+VHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ PY + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPW 127
FP V+ E + LI ++L P K R+ + L PW
Sbjct: 233 FPSPEWDTVTPEAKDLINKMLTINPAK-RITASEALKHPW 271
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 115 bits (276), Expect = 2e-25
Identities = 56/171 (32%), Positives = 95/171 (55%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE+E+ L+H N++R RVY+++EYA G++ ++K DE R +
Sbjct: 178 LRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYI 237
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+L A+ YCH + V+HRDIK ENLL+ +K++DFG++ + + T CG
Sbjct: 238 TELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCG 291
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV 250
+ Y PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++
Sbjct: 292 TLDYLPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI 341
>AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase
ULK1 protein.
Length = 1050
Score = 115 bits (276), Expect = 2e-25
Identities = 69/226 (30%), Positives = 123/226 (54%), Gaps = 12/226 (5%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L +EI+++K LKHEN++ E + VY+VMEY G L D + + + E R +
Sbjct: 60 LGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFL 119
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---------HGLNIKLSDFGFARGHMKPKNGV 430
+Q+ A+ H +G++HRD+K +N+L+ + + +K++DFGFAR +++
Sbjct: 120 QQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFAR-YLQSN--- 175
Query: 429 FALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQL-LKQ 253
++ T CGS Y +PE++ Y + +D+WS+G ++Y + G+ PF ++ L L
Sbjct: 176 -MMAATLCGSPMYMAPEVIMSQHYDGK-ADLWSIGTIVYQCLTGKAPFQASSPQDLRLFY 233
Query: 252 VQNKVSFPREPK-VSAECRKLITRIL-APLKMRVKIPQILADPWLN 121
+NK P P+ SA R+L+ +L K R+ + P+L+
Sbjct: 234 EKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLD 279
>AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein.
Length = 1066
Score = 115 bits (276), Expect = 2e-25
Identities = 69/226 (30%), Positives = 123/226 (54%), Gaps = 12/226 (5%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L +EI+++K LKHEN++ E + VY+VMEY G L D + + + E R +
Sbjct: 76 LGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFL 135
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---------HGLNIKLSDFGFARGHMKPKNGV 430
+Q+ A+ H +G++HRD+K +N+L+ + + +K++DFGFAR +++
Sbjct: 136 QQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFAR-YLQSN--- 191
Query: 429 FALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQL-LKQ 253
++ T CGS Y +PE++ Y + +D+WS+G ++Y + G+ PF ++ L L
Sbjct: 192 -MMAATLCGSPMYMAPEVIMSQHYDGK-ADLWSIGTIVYQCLTGKAPFQASSPQDLRLFY 249
Query: 252 VQNKVSFPREPK-VSAECRKLITRIL-APLKMRVKIPQILADPWLN 121
+NK P P+ SA R+L+ +L K R+ + P+L+
Sbjct: 250 EKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLD 295
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 114 bits (274), Expect = 4e-25
Identities = 63/197 (31%), Positives = 113/197 (57%), Gaps = 1/197 (0%)
Frame = -1
Query: 765 FLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRW 586
++ RE +V+ L H ++ + ++Y + YA+NG LL IRK DET R +
Sbjct: 126 YVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFY 185
Query: 585 FKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+ + P++ A + +F
Sbjct: 186 TAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFV 243
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFP 229
G+ Y SPE+L + SD+W++G ++Y +V G PF N Y K ++ + FP
Sbjct: 244 GTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFP 302
Query: 228 REPKVSAECRKLITRIL 178
K + R L+ ++L
Sbjct: 303 E--KFFPKARDLVEKLL 317
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 114 bits (274), Expect = 4e-25
Identities = 63/197 (31%), Positives = 113/197 (57%), Gaps = 1/197 (0%)
Frame = -1
Query: 765 FLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRW 586
++ RE +V+ L H ++ + ++Y + YA+NG LL IRK DET R +
Sbjct: 126 YVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFY 185
Query: 585 FKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+ + P++ A + +F
Sbjct: 186 TAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFV 243
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFP 229
G+ Y SPE+L + SD+W++G ++Y +V G PF N Y K ++ + FP
Sbjct: 244 GTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFP 302
Query: 228 REPKVSAECRKLITRIL 178
K + R L+ ++L
Sbjct: 303 E--KFFPKARDLVEKLL 317
>BC127622-1|AAI27623.1| 596|Homo sapiens myosin light chain kinase 2,
skeletal muscle protein.
Length = 596
Score = 114 bits (274), Expect = 4e-25
Identities = 85/264 (32%), Positives = 131/264 (49%), Gaps = 8/264 (3%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD-IIRKDQHIDETRG 595
K+ + EIEV+ L H NLI+ AIET H + + MEY E G L + I+ +D H+ E
Sbjct: 324 KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDT 383
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGFARGHMKPKNGVFAL 421
+ +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG AR + N L
Sbjct: 384 MVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRY----NPNEKL 439
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QN 244
F G+ + SPE++ +D+WSMGV+ Y ++ G PF + T+ L V
Sbjct: 440 KVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSG 497
Query: 243 KVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
F E VS E + ++ I+ + R+ Q LA PWLN +L E A
Sbjct: 498 NWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLN----------NLAEKA 547
Query: 72 KTSKEEIKS-VNIGTVTYDRKWKK 4
K +KS + + R+WKK
Sbjct: 548 KRCNRRLKSQILLKKYLMKRRWKK 571
>BC092413-1|AAH92413.1| 596|Homo sapiens myosin light chain kinase 2,
skeletal muscle protein.
Length = 596
Score = 114 bits (274), Expect = 4e-25
Identities = 85/264 (32%), Positives = 131/264 (49%), Gaps = 8/264 (3%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD-IIRKDQHIDETRG 595
K+ + EIEV+ L H NLI+ AIET H + + MEY E G L + I+ +D H+ E
Sbjct: 324 KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDT 383
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGFARGHMKPKNGVFAL 421
+ +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG AR + N L
Sbjct: 384 MVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRY----NPNEKL 439
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QN 244
F G+ + SPE++ +D+WSMGV+ Y ++ G PF + T+ L V
Sbjct: 440 KVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSG 497
Query: 243 KVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
F E VS E + ++ I+ + R+ Q LA PWLN +L E A
Sbjct: 498 NWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLN----------NLAEKA 547
Query: 72 KTSKEEIKS-VNIGTVTYDRKWKK 4
K +KS + + R+WKK
Sbjct: 548 KRCNRRLKSQILLKKYLMKRRWKK 571
>BC069627-1|AAH69627.1| 596|Homo sapiens skeletal myosin light chain
kinase protein.
Length = 596
Score = 114 bits (274), Expect = 4e-25
Identities = 85/264 (32%), Positives = 131/264 (49%), Gaps = 8/264 (3%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD-IIRKDQHIDETRG 595
K+ + EIEV+ L H NLI+ AIET H + + MEY E G L + I+ +D H+ E
Sbjct: 324 KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDT 383
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGFARGHMKPKNGVFAL 421
+ +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG AR + N L
Sbjct: 384 MVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRY----NPNEKL 439
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QN 244
F G+ + SPE++ +D+WSMGV+ Y ++ G PF + T+ L V
Sbjct: 440 KVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSG 497
Query: 243 KVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
F E VS E + ++ I+ + R+ Q LA PWLN +L E A
Sbjct: 498 NWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLN----------NLAEKA 547
Query: 72 KTSKEEIKS-VNIGTVTYDRKWKK 4
K +KS + + R+WKK
Sbjct: 548 KRCNRRLKSQILLKKYLMKRRWKK 571
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 114 bits (274), Expect = 4e-25
Identities = 63/197 (31%), Positives = 113/197 (57%), Gaps = 1/197 (0%)
Frame = -1
Query: 765 FLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRW 586
++ RE +V+ L H ++ + ++Y + YA+NG LL IRK DET R +
Sbjct: 126 YVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFY 185
Query: 585 FKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+ + P++ A + +F
Sbjct: 186 TAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFV 243
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFP 229
G+ Y SPE+L + SD+W++G ++Y +V G PF N Y K ++ + FP
Sbjct: 244 GTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFP 302
Query: 228 REPKVSAECRKLITRIL 178
K + R L+ ++L
Sbjct: 303 E--KFFPKARDLVEKLL 317
>AL160175-10|CAC10006.1| 596|Homo sapiens myosin light chain kinase
2, skeletal muscle protein.
Length = 596
Score = 114 bits (274), Expect = 4e-25
Identities = 85/264 (32%), Positives = 131/264 (49%), Gaps = 8/264 (3%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD-IIRKDQHIDETRG 595
K+ + EIEV+ L H NLI+ AIET H + + MEY E G L + I+ +D H+ E
Sbjct: 324 KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDT 383
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGFARGHMKPKNGVFAL 421
+ +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG AR + N L
Sbjct: 384 MVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRY----NPNEKL 439
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QN 244
F G+ + SPE++ +D+WSMGV+ Y ++ G PF + T+ L V
Sbjct: 440 KVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSG 497
Query: 243 KVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
F E VS E + ++ I+ + R+ Q LA PWLN +L E A
Sbjct: 498 NWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLN----------NLAEKA 547
Query: 72 KTSKEEIKS-VNIGTVTYDRKWKK 4
K +KS + + R+WKK
Sbjct: 548 KRCNRRLKSQILLKKYLMKRRWKK 571
>AJ272502-1|CAC81354.1| 596|Homo sapiens skeletal muscle-specific
myosin light chain kinase protein.
Length = 596
Score = 114 bits (274), Expect = 4e-25
Identities = 85/264 (32%), Positives = 131/264 (49%), Gaps = 8/264 (3%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD-IIRKDQHIDETRG 595
K+ + EIEV+ L H NLI+ AIET H + + MEY E G L + I+ +D H+ E
Sbjct: 324 KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDT 383
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGFARGHMKPKNGVFAL 421
+ +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG AR + N L
Sbjct: 384 MVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRY----NPNEKL 439
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QN 244
F G+ + SPE++ +D+WSMGV+ Y ++ G PF + T+ L V
Sbjct: 440 KVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSG 497
Query: 243 KVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
F E VS E + ++ I+ + R+ Q LA PWLN +L E A
Sbjct: 498 NWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLN----------NLAEKA 547
Query: 72 KTSKEEIKS-VNIGTVTYDRKWKK 4
K +KS + + R+WKK
Sbjct: 548 KRCNRRLKSQILLKKYLMKRRWKK 571
>AF325549-1|AAK15494.1| 596|Homo sapiens skeletal myosin light chain
kinase protein.
Length = 596
Score = 114 bits (274), Expect = 4e-25
Identities = 85/264 (32%), Positives = 131/264 (49%), Gaps = 8/264 (3%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLD-IIRKDQHIDETRG 595
K+ + EIEV+ L H NLI+ AIET H + + MEY E G L + I+ +D H+ E
Sbjct: 324 KEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDT 383
Query: 594 RRWFKQLVEAVDYCHERGVVHRDIKCENLLMDH--GLNIKLSDFGFARGHMKPKNGVFAL 421
+ +Q+ + + + H+ V+H D+K EN+L + G +K+ DFG AR + N L
Sbjct: 384 MVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRY----NPNEKL 439
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QN 244
F G+ + SPE++ +D+WSMGV+ Y ++ G PF + T+ L V
Sbjct: 440 KVNF-GTPEFLSPEVV-NYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSG 497
Query: 243 KVSFPRE--PKVSAECRKLITR-ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHA 73
F E VS E + ++ I+ + R+ Q LA PWLN +L E A
Sbjct: 498 NWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLN----------NLAEKA 547
Query: 72 KTSKEEIKS-VNIGTVTYDRKWKK 4
K +KS + + R+WKK
Sbjct: 548 KRCNRRLKSQILLKKYLMKRRWKK 571
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 114 bits (274), Expect = 4e-25
Identities = 63/197 (31%), Positives = 113/197 (57%), Gaps = 1/197 (0%)
Frame = -1
Query: 765 FLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRW 586
++ RE +V+ L H ++ + ++Y + YA+NG LL IRK DET R +
Sbjct: 126 YVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFY 185
Query: 585 FKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+ + P++ A + +F
Sbjct: 186 TAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFV 243
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFP 229
G+ Y SPE+L + SD+W++G ++Y +V G PF N Y K ++ + FP
Sbjct: 244 GTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFP 302
Query: 228 REPKVSAECRKLITRIL 178
K + R L+ ++L
Sbjct: 303 E--KFFPKARDLVEKLL 317
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 114 bits (274), Expect = 4e-25
Identities = 63/197 (31%), Positives = 113/197 (57%), Gaps = 1/197 (0%)
Frame = -1
Query: 765 FLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRW 586
++ RE +V+ L H ++ + ++Y + YA+NG LL IRK DET R +
Sbjct: 118 YVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFY 177
Query: 585 FKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+ + P++ A + +F
Sbjct: 178 TAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFV 235
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFP 229
G+ Y SPE+L + SD+W++G ++Y +V G PF N Y K ++ + FP
Sbjct: 236 GTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFP 294
Query: 228 REPKVSAECRKLITRIL 178
K + R L+ ++L
Sbjct: 295 E--KFFPKARDLVEKLL 309
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 114 bits (274), Expect = 4e-25
Identities = 63/197 (31%), Positives = 113/197 (57%), Gaps = 1/197 (0%)
Frame = -1
Query: 765 FLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRW 586
++ RE +V+ L H ++ + ++Y + YA+NG LL IRK DET R +
Sbjct: 164 YVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFY 223
Query: 585 FKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
++V A++Y H +G++HRD+K EN+L++ ++I+++DFG A+ + P++ A + +F
Sbjct: 224 TAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFV 281
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFP 229
G+ Y SPE+L + SD+W++G ++Y +V G PF N Y K ++ + FP
Sbjct: 282 GTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFP 340
Query: 228 REPKVSAECRKLITRIL 178
K + R L+ ++L
Sbjct: 341 E--KFFPKARDLVEKLL 355
>Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein.
Length = 445
Score = 113 bits (273), Expect = 5e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 610
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 609 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 445
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 444 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 265
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 264 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 94
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 93 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 4
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>U23460-1|AAC99802.1| 664|Homo sapiens proline rich
calmodulin-dependent protein kinase protein.
Length = 664
Score = 113 bits (273), Expect = 5e-25
Identities = 73/221 (33%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHPWV 272
>U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase 1
protein.
Length = 445
Score = 113 bits (273), Expect = 5e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 610
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 609 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 445
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 444 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 265
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 264 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 94
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 93 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 4
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>L24959-1|AAA18251.1| 473|Homo sapiens calcium/calmodulin dependent
protein kinase protein.
Length = 473
Score = 113 bits (273), Expect = 5e-25
Identities = 75/224 (33%), Positives = 119/224 (53%), Gaps = 8/224 (3%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 421
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ-LLKQVQN 244
+T CG+ Y +PEIL+G Y P + D+WS+G++ Y ++ G PF D Q + +++ N
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILN 256
Query: 243 KVSF---PREPKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 124
+ P +VS + L+ + I+ K R+ Q L PW+
Sbjct: 257 CEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>L17000-1|AAA35639.1| 473|Homo sapiens calcium/calmodulin-dependent
protein kinase protein.
Length = 473
Score = 113 bits (273), Expect = 5e-25
Identities = 75/224 (33%), Positives = 119/224 (53%), Gaps = 8/224 (3%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 421
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ-LLKQVQN 244
+T CG+ Y +PEIL+G Y P + D+WS+G++ Y ++ G PF D Q + +++ N
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILN 256
Query: 243 KVSF---PREPKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 124
+ P +VS + L+ + I+ K R+ Q L PW+
Sbjct: 257 CEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>D30742-1|BAA06403.1| 473|Homo sapiens calmodulin-dependent protein
kinase IV protein.
Length = 473
Score = 113 bits (273), Expect = 5e-25
Identities = 75/224 (33%), Positives = 119/224 (53%), Gaps = 8/224 (3%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 421
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ-LLKQVQN 244
+T CG+ Y +PEIL+G Y P + D+WS+G++ Y ++ G PF D Q + +++ N
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILN 256
Query: 243 KVSF---PREPKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 124
+ P +VS + L+ + I+ K R+ Q L PW+
Sbjct: 257 CEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 113 bits (273), Expect = 5e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 610
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 609 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 445
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 444 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 265
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 264 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 94
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 93 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 4
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein.
Length = 326
Score = 113 bits (273), Expect = 5e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 610
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 609 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 445
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 444 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 265
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 264 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 94
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 93 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 4
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 113 bits (273), Expect = 5e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 610
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 609 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 445
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 444 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 265
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 264 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 94
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 93 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 4
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>BC025687-1|AAH25687.1| 473|Homo sapiens
calcium/calmodulin-dependent protein kinase IV protein.
Length = 473
Score = 113 bits (273), Expect = 5e-25
Identities = 75/224 (33%), Positives = 119/224 (53%), Gaps = 8/224 (3%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 83 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 142
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 421
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 143 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 197
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ-LLKQVQN 244
+T CG+ Y +PEIL+G Y P + D+WS+G++ Y ++ G PF D Q + +++ N
Sbjct: 198 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILN 256
Query: 243 KVSF---PREPKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 124
+ P +VS + L+ + I+ K R+ Q L PW+
Sbjct: 257 CEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 300
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>BC019070-1|AAH19070.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II beta protein.
Length = 503
Score = 113 bits (273), Expect = 5e-25
Identities = 73/221 (33%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHPWV 272
>BC016695-1|AAH16695.2| 503|Homo sapiens CAMK4 protein protein.
Length = 503
Score = 113 bits (273), Expect = 5e-25
Identities = 75/224 (33%), Positives = 119/224 (53%), Gaps = 8/224 (3%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGR 592
KK + EI V+ L H N+I+ + ET + +V+E G L D I + + E
Sbjct: 113 KKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAA 172
Query: 591 RWFKQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFAL 421
KQ++EAV Y HE G+VHRD+K ENLL +K++DFG ++ ++ V L
Sbjct: 173 DAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSK---IVEHQV--L 227
Query: 420 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ-LLKQVQN 244
+T CG+ Y +PEIL+G Y P + D+WS+G++ Y ++ G PF D Q + +++ N
Sbjct: 228 MKTVCGTPGYCAPEILRGCAYGP-EVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILN 286
Query: 243 KVSF---PREPKVSAECRKLITR-ILAPLKMRVKIPQILADPWL 124
+ P +VS + L+ + I+ K R+ Q L PW+
Sbjct: 287 CEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWV 330
>AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase
protein.
Length = 384
Score = 113 bits (273), Expect = 5e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 610
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 609 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 445
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 444 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 265
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 264 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 94
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 93 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 4
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 protein.
Length = 445
Score = 113 bits (273), Expect = 5e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 610
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 609 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 445
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 444 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 265
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 264 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 94
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 93 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 4
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 2 variant protein.
Length = 445
Score = 113 bits (273), Expect = 5e-25
Identities = 88/270 (32%), Positives = 138/270 (51%), Gaps = 14/270 (5%)
Frame = -1
Query: 771 KKFLPREIEVVKGLKHENLIRFLQAI--ETTHRVYIVMEYAENGSLLDIIRKD----QHI 610
K+ L E+ +++ LKH N++R+ I T +YIVMEY E G L +I K Q++
Sbjct: 49 KQMLVSEVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYL 108
Query: 609 DETRGRRWFKQLVEAVDYCHERG-----VVHRDIKCENLLMDHGLNIKLSDFGFARGHMK 445
DE R QL A+ CH R V+HRD+K N+ +D N+KL DFG AR
Sbjct: 109 DEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLAR---- 164
Query: 444 PKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ 265
N + ++TF G+ Y SPE + + Y + SD+WS+G +LY + PF + +
Sbjct: 165 ILNHDTSFAKTFVGTPYYMSPEQMNRMSYN-EKSDIWSLGCLLYELCALMPPFTAFSQKE 223
Query: 264 LLKQVQNKVSFPREP-KVSAECRKLITRILAPLK--MRVKIPQILADPWLNPNQQSKHDE 94
L +++ + F R P + S E ++ITR+L LK R + +IL +P L + +
Sbjct: 224 LAGKIR-EGKFRRIPYRYSDELNEIITRML-NLKDYHRPSVEEILENP-LIADLVADEQR 280
Query: 93 TDLQEHAKTSKEEIKSVNIGTVTYDRKWKK 4
+L+ + E KS + V + K K+
Sbjct: 281 RNLERRGRQLGEPEKSQDSSPVLSELKLKE 310
>AK222703-1|BAD96423.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase IIB isoform
2 variant protein.
Length = 542
Score = 113 bits (273), Expect = 5e-25
Identities = 73/221 (33%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHPWV 272
>AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 4 protein.
Length = 518
Score = 113 bits (273), Expect = 5e-25
Identities = 73/221 (33%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHPWV 272
>AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 2 protein.
Length = 479
Score = 113 bits (273), Expect = 5e-25
Identities = 73/221 (33%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHPWV 272
>AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin
dependent protein kinase II beta 1 protein.
Length = 503
Score = 113 bits (273), Expect = 5e-25
Identities = 73/221 (33%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHPWV 272
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>AF140350-1|AAD42070.1| 449|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 7
subunit protein.
Length = 449
Score = 113 bits (273), Expect = 5e-25
Identities = 73/221 (33%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHPWV 272
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 113 bits (273), Expect = 5e-25
Identities = 62/193 (32%), Positives = 109/193 (56%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL++D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>AF083419-1|AAD42038.1| 517|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e
subunit protein.
Length = 517
Score = 113 bits (273), Expect = 5e-25
Identities = 73/221 (33%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHPWV 272
>AF081924-1|AAD42037.1| 492|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta 6
subunit protein.
Length = 492
Score = 113 bits (273), Expect = 5e-25
Identities = 73/221 (33%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHPWV 272
>AF081572-1|AAD42036.1| 503|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta e'
subunit protein.
Length = 503
Score = 113 bits (273), Expect = 5e-25
Identities = 73/221 (33%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHPWV 272
>AF078803-1|AAD42035.1| 542|Homo sapiens
calcium/calmodulin-dependent protein kinase II beta
subunit protein.
Length = 542
Score = 113 bits (273), Expect = 5e-25
Identities = 73/221 (33%), Positives = 114/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L RE + + LKH N++R +I Y+V + G L + I ++ E
Sbjct: 58 LEREARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCI 117
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLMD---HGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++EAV +CH+ GVVHRD+K ENLL+ G +KL+DFG A + F
Sbjct: 118 QQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFG---- 173
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVS 235
F G+ Y SPE+L+ Y + D+W+ GV+LY ++ G PF D + +L +Q++
Sbjct: 174 FAGTPGYLSPEVLRKEAY-GKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYD 232
Query: 234 FPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
FP V+ E + LI ++L P K R+ + L PW+
Sbjct: 233 FPSPEWDTVTPEAKNLINQMLTINPAK-RITAHEALKHPWV 272
>BC012622-1|AAH12622.1| 207|Homo sapiens PRKAA1 protein protein.
Length = 207
Score = 113 bits (272), Expect = 7e-25
Identities = 55/130 (42%), Positives = 80/130 (61%)
Frame = -1
Query: 756 REIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQ 577
REI+ +K +H ++I+ Q I T +++VMEY G L D I K+ +DE RR F+Q
Sbjct: 65 REIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQ 124
Query: 576 LVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 397
++ VDYCH VVHRD+K EN+L+D +N K++DFG + +G F T CGS
Sbjct: 125 ILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSP 179
Query: 396 AYASPEILKG 367
YA+PE++ G
Sbjct: 180 NYAAPEVISG 189
>BC035745-1|AAH35745.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 113 bits (271), Expect = 9e-25
Identities = 71/221 (32%), Positives = 113/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ EI V++ +KHEN++ E+ + +Y+VM+ G L D I + E
Sbjct: 66 IENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q+++AV Y H G+VHRD+K ENLL D I +SDFG ++ M+ K V + T
Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS---T 180
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNK 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF D N ++L +Q+ + +
Sbjct: 181 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239
Query: 240 VSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
P +S + I ++ P K R Q PW+
Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNK-RYTCEQAARHPWI 279
>AL731559-2|CAI14675.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 113 bits (271), Expect = 9e-25
Identities = 71/221 (32%), Positives = 113/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ EI V++ +KHEN++ E+ + +Y+VM+ G L D I + E
Sbjct: 66 IENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q+++AV Y H G+VHRD+K ENLL D I +SDFG ++ M+ K V + T
Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS---T 180
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNK 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF D N ++L +Q+ + +
Sbjct: 181 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239
Query: 240 VSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
P +S + I ++ P K R Q PW+
Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNK-RYTCEQAARHPWI 279
>AL731559-1|CAI14674.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 113 bits (271), Expect = 9e-25
Identities = 71/221 (32%), Positives = 113/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ EI V++ +KHEN++ E+ + +Y+VM+ G L D I + E
Sbjct: 66 IENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q+++AV Y H G+VHRD+K ENLL D I +SDFG ++ M+ K V + T
Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS---T 180
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNK 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF D N ++L +Q+ + +
Sbjct: 181 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239
Query: 240 VSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
P +S + I ++ P K R Q PW+
Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNK-RYTCEQAARHPWI 279
>AL512783-2|CAH74036.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 113 bits (271), Expect = 9e-25
Identities = 71/221 (32%), Positives = 113/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ EI V++ +KHEN++ E+ + +Y+VM+ G L D I + E
Sbjct: 66 IENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q+++AV Y H G+VHRD+K ENLL D I +SDFG ++ M+ K V + T
Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS---T 180
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNK 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF D N ++L +Q+ + +
Sbjct: 181 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239
Query: 240 VSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
P +S + I ++ P K R Q PW+
Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNK-RYTCEQAARHPWI 279
>AL512783-1|CAH74035.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 113 bits (271), Expect = 9e-25
Identities = 71/221 (32%), Positives = 113/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ EI V++ +KHEN++ E+ + +Y+VM+ G L D I + E
Sbjct: 66 IENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q+++AV Y H G+VHRD+K ENLL D I +SDFG ++ M+ K V + T
Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS---T 180
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNK 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF D N ++L +Q+ + +
Sbjct: 181 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239
Query: 240 VSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
P +S + I ++ P K R Q PW+
Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNK-RYTCEQAARHPWI 279
>AL512284-2|CAH71694.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 113 bits (271), Expect = 9e-25
Identities = 71/221 (32%), Positives = 113/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ EI V++ +KHEN++ E+ + +Y+VM+ G L D I + E
Sbjct: 66 IENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q+++AV Y H G+VHRD+K ENLL D I +SDFG ++ M+ K V + T
Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS---T 180
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNK 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF D N ++L +Q+ + +
Sbjct: 181 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239
Query: 240 VSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
P +S + I ++ P K R Q PW+
Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNK-RYTCEQAARHPWI 279
>AL512284-1|CAH71693.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 113 bits (271), Expect = 9e-25
Identities = 71/221 (32%), Positives = 113/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ EI V++ +KHEN++ E+ + +Y+VM+ G L D I + E
Sbjct: 66 IENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q+++AV Y H G+VHRD+K ENLL D I +SDFG ++ M+ K V + T
Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS---T 180
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNK 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF D N ++L +Q+ + +
Sbjct: 181 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239
Query: 240 VSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
P +S + I ++ P K R Q PW+
Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNK-RYTCEQAARHPWI 279
>AL391314-2|CAI14410.1| 385|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 385
Score = 113 bits (271), Expect = 9e-25
Identities = 71/221 (32%), Positives = 113/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ EI V++ +KHEN++ E+ + +Y+VM+ G L D I + E
Sbjct: 66 IENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q+++AV Y H G+VHRD+K ENLL D I +SDFG ++ M+ K V + T
Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS---T 180
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNK 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF D N ++L +Q+ + +
Sbjct: 181 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239
Query: 240 VSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
P +S + I ++ P K R Q PW+
Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNK-RYTCEQAARHPWI 279
>AL391314-1|CAI14409.1| 357|Homo sapiens
calcium/calmodulin-dependent protein kinase ID protein.
Length = 357
Score = 113 bits (271), Expect = 9e-25
Identities = 71/221 (32%), Positives = 113/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ EI V++ +KHEN++ E+ + +Y+VM+ G L D I + E
Sbjct: 66 IENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q+++AV Y H G+VHRD+K ENLL D I +SDFG ++ M+ K V + T
Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS---T 180
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNK 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF D N ++L +Q+ + +
Sbjct: 181 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239
Query: 240 VSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
P +S + I ++ P K R Q PW+
Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNK-RYTCEQAARHPWI 279
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 113 bits (271), Expect = 9e-25
Identities = 63/197 (31%), Positives = 112/197 (56%), Gaps = 1/197 (0%)
Frame = -1
Query: 765 FLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRW 586
++ RE +V+ L H ++ + ++Y + YA+NG LL IRK DET R +
Sbjct: 126 YVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFY 185
Query: 585 FKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
++V A +Y H +G++HRD+K EN+L++ ++I+++DFG A+ + P++ A + +F
Sbjct: 186 TAEIVSASEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAK-VLSPESKQ-ARANSFV 243
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFP 229
G+ Y SPE+L + SD+W++G ++Y +V G PF N Y K ++ + FP
Sbjct: 244 GTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFP 302
Query: 228 REPKVSAECRKLITRIL 178
K + R L+ ++L
Sbjct: 303 E--KFFPKARDLVEKLL 317
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 113 bits (271), Expect = 9e-25
Identities = 63/197 (31%), Positives = 112/197 (56%), Gaps = 1/197 (0%)
Frame = -1
Query: 765 FLPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRW 586
++ RE +V+ L H ++ + ++Y + YA+NG LL IRK DET R +
Sbjct: 99 YVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFY 158
Query: 585 FKQLVEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 406
++V A++Y H +G++HRD+K EN+L++ + I+++DFG A+ + P++ A + +F
Sbjct: 159 TAEIVSALEYLHGKGIIHRDLKPENILLNEDMYIQITDFGTAK-VLSPESKQ-ARANSFV 216
Query: 405 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTN-YTQLLKQVQNKVSFP 229
G+ Y SPE+L + SD+W++G ++Y +V G PF N Y K ++ + FP
Sbjct: 217 GTAQYVSPELLT-EKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFP 275
Query: 228 REPKVSAECRKLITRIL 178
K + R L+ ++L
Sbjct: 276 E--KFFPKARDLVEKLL 290
>AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kinase
protein.
Length = 357
Score = 113 bits (271), Expect = 9e-25
Identities = 71/221 (32%), Positives = 113/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ EI V++ +KHEN++ E+ + +Y+VM+ G L D I + E
Sbjct: 66 IENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q+++AV Y H G+VHRD+K ENLL D I +SDFG ++ M+ K V + T
Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS---T 180
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNK 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF D N ++L +Q+ + +
Sbjct: 181 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239
Query: 240 VSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
P +S + I ++ P K R Q PW+
Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNK-RYTCEQAARHPWI 279
>AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase RLPK
protein.
Length = 802
Score = 113 bits (271), Expect = 9e-25
Identities = 78/232 (33%), Positives = 124/232 (53%), Gaps = 16/232 (6%)
Frame = -1
Query: 756 REIEVVKGLK-HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFK 580
+EI +K + H N+++ + ++VME G L + I+K +H ET +
Sbjct: 467 KEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMR 526
Query: 579 QLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETF 409
+LV AV + H+ GVVHRD+K ENLL + L IK+ DFGFAR +KP + +T
Sbjct: 527 KLVSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFAR--LKPPDN--QPLKTP 582
Query: 408 CGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-------TNYTQLLKQV 250
C + YA+PE+L Y + D+WS+GV+LY ++ G++PF T+ +++K++
Sbjct: 583 CFTLHYAAPELLNQNGY-DESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKI 641
Query: 249 -QNKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWLNPNQQ 109
+ SF E VS E + LI +L P K R+K+ + + WL Q
Sbjct: 642 KKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNK-RLKMSGLRYNEWLQDGSQ 692
Score = 87.8 bits (208), Expect = 4e-17
Identities = 48/184 (26%), Positives = 101/184 (54%), Gaps = 4/184 (2%)
Frame = -1
Query: 717 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 538
L+ A +T +++++++Y G L + + + E + + ++V A+++ H+ G+
Sbjct: 114 LVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGI 173
Query: 537 VHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPY 358
++RDIK EN+L+D ++ L+DFG ++ + + + +FCG+ Y +P+I++G
Sbjct: 174 IYRDIKLENILLDSNGHVVLTDFGLSKEFVADET---ERAYSFCGTIEYMAPDIVRGGDS 230
Query: 357 -RPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKV--SFPREP-KVSAECRKLI 190
+ D WS+GV++Y ++ G PF ++ ++ S P P ++SA + LI
Sbjct: 231 GHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLI 290
Query: 189 TRIL 178
R+L
Sbjct: 291 QRLL 294
>AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and
stress-activated protein kinase-1 protein.
Length = 802
Score = 113 bits (271), Expect = 9e-25
Identities = 78/232 (33%), Positives = 124/232 (53%), Gaps = 16/232 (6%)
Frame = -1
Query: 756 REIEVVKGLK-HENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFK 580
+EI +K + H N+++ + ++VME G L + I+K +H ET +
Sbjct: 467 KEITALKLCEGHPNIVKLHEVFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMR 526
Query: 579 QLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETF 409
+LV AV + H+ GVVHRD+K ENLL + L IK+ DFGFAR +KP + +T
Sbjct: 527 KLVSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFAR--LKPPDN--QPLKTP 582
Query: 408 CGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-------TNYTQLLKQV 250
C + YA+PE+L Y + D+WS+GV+LY ++ G++PF T+ +++K++
Sbjct: 583 CFTLHYAAPELLNQNGY-DESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKI 641
Query: 249 -QNKVSFPRE--PKVSAECRKLITRILA--PLKMRVKIPQILADPWLNPNQQ 109
+ SF E VS E + LI +L P K R+K+ + + WL Q
Sbjct: 642 KKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNK-RLKMSGLRYNEWLQDGSQ 692
Score = 87.8 bits (208), Expect = 4e-17
Identities = 48/184 (26%), Positives = 101/184 (54%), Gaps = 4/184 (2%)
Frame = -1
Query: 717 LIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQLVEAVDYCHERGV 538
L+ A +T +++++++Y G L + + + E + + ++V A+++ H+ G+
Sbjct: 114 LVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGI 173
Query: 537 VHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPY 358
++RDIK EN+L+D ++ L+DFG ++ + + + +FCG+ Y +P+I++G
Sbjct: 174 IYRDIKLENILLDSNGHVVLTDFGLSKEFVADET---ERAYSFCGTIEYMAPDIVRGGDS 230
Query: 357 -RPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKV--SFPREP-KVSAECRKLI 190
+ D WS+GV++Y ++ G PF ++ ++ S P P ++SA + LI
Sbjct: 231 GHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLI 290
Query: 189 TRIL 178
R+L
Sbjct: 291 QRLL 294
>AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta
protein.
Length = 385
Score = 113 bits (271), Expect = 9e-25
Identities = 71/221 (32%), Positives = 113/221 (51%), Gaps = 8/221 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
+ EI V++ +KHEN++ E+ + +Y+VM+ G L D I + E
Sbjct: 66 IENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLI 125
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLL---MDHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q+++AV Y H G+VHRD+K ENLL D I +SDFG ++ M+ K V + T
Sbjct: 126 RQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSK--MEGKGDVMS---T 180
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNK 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF D N ++L +Q+ + +
Sbjct: 181 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYE 239
Query: 240 VSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWL 124
P +S + I ++ P K R Q PW+
Sbjct: 240 FDSPYWDDISDSAKDFIRNLMEKDPNK-RYTCEQAARHPWI 279
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 112 bits (270), Expect = 1e-24
Identities = 62/193 (32%), Positives = 108/193 (55%), Gaps = 1/193 (0%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E V+K +H L + +T R+ VMEY G L + +++ E R R + ++
Sbjct: 196 ESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEI 255
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 394
V A+DY H +V+RD+K ENL+ D +IK++DFG + + A +TFCG+
Sbjct: 256 VSALDYLHSGKIVYRDLKLENLMRDKDGHIKITDFGLCKEGITDA----ATMKTFCGTPE 311
Query: 393 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPK 217
Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FPR
Sbjct: 312 YLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR--T 368
Query: 216 VSAECRKLITRIL 178
+S++ + L++ +L
Sbjct: 369 LSSDAKSLLSGLL 381
>BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 112 bits (269), Expect = 2e-24
Identities = 67/217 (30%), Positives = 116/217 (53%), Gaps = 7/217 (3%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E+ V++ + H +++ ++ ET +VY+VME A G L D + E R + +
Sbjct: 108 ELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMV 167
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ + Y H + HR++K ENLL H I ++DFG A + K+G + + +T CG
Sbjct: 168 ADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA--YSGKKSGDWTM-KTLCG 224
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR 226
+ Y +PE+L PY D+W++GV+ YA++ G LPFDD + T+L +++ + K ++
Sbjct: 225 TPEYIAPEVLLRKPY-TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTG 283
Query: 225 E--PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
E P +S + I ++L R+ Q L PW+
Sbjct: 284 EPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV 320
>BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 112 bits (269), Expect = 2e-24
Identities = 67/217 (30%), Positives = 116/217 (53%), Gaps = 7/217 (3%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E+ V++ + H +++ ++ ET +VY+VME A G L D + E R + +
Sbjct: 108 ELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMV 167
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ + Y H + HR++K ENLL H I ++DFG A + K+G + + +T CG
Sbjct: 168 ADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA--YSGKKSGDWTM-KTLCG 224
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR 226
+ Y +PE+L PY D+W++GV+ YA++ G LPFDD + T+L +++ + K ++
Sbjct: 225 TPEYIAPEVLLRKPY-TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTG 283
Query: 225 E--PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
E P +S + I ++L R+ Q L PW+
Sbjct: 284 EPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV 320
>BC032787-1|AAH32787.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 112 bits (269), Expect = 2e-24
Identities = 70/229 (30%), Positives = 114/229 (49%), Gaps = 7/229 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L EI V+K +KHEN++ E+T Y+VM+ G L D I + E
Sbjct: 65 LENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVI 124
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++ AV Y HE G+VHRD+K ENLL + I ++DFG ++ +NG+ + T
Sbjct: 125 QQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK---MEQNGIMS---T 178
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN---K 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF + ++L ++++ +
Sbjct: 179 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYE 237
Query: 240 VSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWLNPNQQSKHD 97
P +S + I +L R + L+ PW++ N D
Sbjct: 238 FESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRD 286
>AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein.
Length = 460
Score = 112 bits (269), Expect = 2e-24
Identities = 70/229 (30%), Positives = 114/229 (49%), Gaps = 7/229 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L EI V+K +KHEN++ E+T Y+VM+ G L D I + E
Sbjct: 65 LENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVI 124
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++ AV Y HE G+VHRD+K ENLL + I ++DFG ++ +NG+ + T
Sbjct: 125 QQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK---MEQNGIMS---T 178
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN---K 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF + ++L ++++ +
Sbjct: 179 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYE 237
Query: 240 VSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWLNPNQQSKHD 97
P +S + I +L R + L+ PW++ N D
Sbjct: 238 FESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRD 286
>AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase
PSKH2 protein.
Length = 385
Score = 112 bits (269), Expect = 2e-24
Identities = 67/217 (30%), Positives = 116/217 (53%), Gaps = 7/217 (3%)
Frame = -1
Query: 753 EIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWFKQL 574
E+ V++ + H +++ ++ ET +VY+VME A G L D + E R + +
Sbjct: 108 ELSVLRRVSHRYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMV 167
Query: 573 VEAVDYCHERGVVHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCG 403
+ + Y H + HR++K ENLL H I ++DFG A + K+G + + +T CG
Sbjct: 168 ADGIRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA--YSGKKSGDWTM-KTLCG 224
Query: 402 SYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR 226
+ Y +PE+L PY D+W++GV+ YA++ G LPFDD + T+L +++ + K ++
Sbjct: 225 TPEYIAPEVLLRKPY-TSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTG 283
Query: 225 E--PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 124
E P +S + I ++L R+ Q L PW+
Sbjct: 284 EPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV 320
>AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein
protein.
Length = 481
Score = 112 bits (269), Expect = 2e-24
Identities = 70/229 (30%), Positives = 114/229 (49%), Gaps = 7/229 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L EI V+K +KHEN++ E+T Y+VM+ G L D I + E
Sbjct: 70 LENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVI 129
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++ AV Y HE G+VHRD+K ENLL + I ++DFG ++ +NG+ + T
Sbjct: 130 QQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK---MEQNGIMS---T 183
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN---K 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF + ++L ++++ +
Sbjct: 184 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYE 242
Query: 240 VSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWLNPNQQSKHD 97
P +S + I +L R + L+ PW++ N D
Sbjct: 243 FESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRD 291
>AL023754-3|CAI19991.1| 476|Homo sapiens
calcium/calmodulin-dependent protein kinase IG protein.
Length = 476
Score = 112 bits (269), Expect = 2e-24
Identities = 70/229 (30%), Positives = 114/229 (49%), Gaps = 7/229 (3%)
Frame = -1
Query: 762 LPREIEVVKGLKHENLIRFLQAIETTHRVYIVMEYAENGSLLDIIRKDQHIDETRGRRWF 583
L EI V+K +KHEN++ E+T Y+VM+ G L D I + E
Sbjct: 65 LENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVI 124
Query: 582 KQLVEAVDYCHERGVVHRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSET 412
+Q++ AV Y HE G+VHRD+K ENLL + I ++DFG ++ +NG+ + T
Sbjct: 125 QQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSK---MEQNGIMS---T 178
Query: 411 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN---K 241
CG+ Y +PE+L PY + D WS+GV+ Y ++ G PF + ++L ++++ +
Sbjct: 179 ACGTPGYVAPEVLAQKPY-SKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYE 237
Query: 240 VSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWLNPNQQSKHD 97
P +S + I +L R + L+ PW++ N D
Sbjct: 238 FESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRD 286
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,154,084
Number of Sequences: 237096
Number of extensions: 2549813
Number of successful extensions: 12027
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 7780
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8492
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9478778060
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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