Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmte11o12
(865 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein. 162 1e-39
BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine ... 162 1e-39
AF362953-1|AAK98531.1| 358|Homo sapiens testis specific serine/... 162 1e-39
AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine ... 162 1e-39
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 160 7e-39
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 160 7e-39
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 160 7e-39
BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein. 145 2e-34
AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine ... 145 2e-34
BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine ... 144 5e-34
AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein. 144 5e-34
AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine ... 144 5e-34
AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific serine/... 144 5e-34
AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens ... 142 1e-33
AF542390-1|AAN62841.1| 258|Homo sapiens AT03158-like protein pr... 142 2e-33
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 126 1e-28
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 126 1e-28
BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine ... 120 7e-27
AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protei... 120 7e-27
AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens ... 118 2e-26
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 111 4e-24
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 111 4e-24
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 111 4e-24
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 111 4e-24
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 111 4e-24
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 111 4e-24
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 109 1e-23
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 109 1e-23
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 109 1e-23
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 109 1e-23
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 109 1e-23
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 108 3e-23
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 105 2e-22
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 105 2e-22
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 105 2e-22
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 105 2e-22
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 105 2e-22
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 105 2e-22
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 105 3e-22
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 105 3e-22
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 105 3e-22
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 105 3e-22
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 105 3e-22
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 105 3e-22
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 105 3e-22
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 105 3e-22
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 103 6e-22
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 103 6e-22
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 103 6e-22
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 103 6e-22
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 103 6e-22
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 103 6e-22
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 103 6e-22
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 101 4e-21
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 101 4e-21
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 101 4e-21
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 101 4e-21
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 100 1e-20
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 100 1e-20
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 100 1e-20
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 99 2e-20
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 99 2e-20
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 99 2e-20
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 99 2e-20
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 99 2e-20
AB183428-1|BAF73616.1| 580|Homo sapiens maternal embryonic luec... 99 2e-20
AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leuc... 99 2e-20
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 97 6e-20
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 97 6e-20
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 97 6e-20
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 97 6e-20
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 97 6e-20
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 97 6e-20
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 97 6e-20
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 97 6e-20
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 97 6e-20
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 97 6e-20
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 97 6e-20
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 97 6e-20
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 97 7e-20
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 97 7e-20
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 96 1e-19
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 93 9e-19
BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H... 93 2e-18
AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase p... 93 2e-18
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 91 5e-18
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 91 5e-18
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 91 5e-18
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 90 1e-17
M14504-1|AAA36519.1| 150|Homo sapiens protein ( Human protein-s... 89 1e-17
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 88 3e-17
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 88 3e-17
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 88 3e-17
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 88 3e-17
BC031647-1|AAH31647.1| 520|Homo sapiens calcium/calmodulin-depe... 88 3e-17
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 88 3e-17
BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H... 87 6e-17
BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H... 87 6e-17
AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase... 87 6e-17
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 86 1e-16
D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein. 86 1e-16
BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing s... 86 1e-16
BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein. 86 1e-16
BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog... 86 1e-16
BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein. 86 1e-16
AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog... 86 1e-16
AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein. 86 1e-16
AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein. 86 1e-16
AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein. 86 1e-16
AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein. 86 1e-16
AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-depende... 85 2e-16
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 85 2e-16
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 85 3e-16
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 85 3e-16
U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein ... 85 4e-16
BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-depe... 83 2e-15
AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein pr... 83 2e-15
AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-depende... 83 2e-15
AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-depende... 83 2e-15
AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform pr... 83 2e-15
AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-depe... 83 2e-15
AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-depe... 83 2e-15
AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-depende... 83 2e-15
AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-depende... 83 2e-15
AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein. 83 2e-15
AK058166-1|BAB71697.1| 128|Homo sapiens protein ( Homo sapiens ... 82 2e-15
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 81 4e-15
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 80 9e-15
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 80 9e-15
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 80 9e-15
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 79 2e-14
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 79 2e-14
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 79 2e-14
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 79 2e-14
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 79 2e-14
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 79 2e-14
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 79 2e-14
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 79 2e-14
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 79 2e-14
AB004885-1|BAA20562.1| 787|Homo sapiens PKU-beta protein. 78 4e-14
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 78 5e-14
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 78 5e-14
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 78 5e-14
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 78 5e-14
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 78 5e-14
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 78 5e-14
AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting ... 78 5e-14
BC071948-1|AAH71948.1| 97|Homo sapiens MARK4 protein protein. 77 6e-14
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 77 6e-14
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 77 6e-14
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 77 1e-13
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 77 1e-13
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 77 1e-13
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 77 1e-13
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 77 1e-13
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 77 1e-13
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 77 1e-13
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 77 1e-13
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 77 1e-13
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 77 1e-13
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 77 1e-13
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 77 1e-13
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 77 1e-13
AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform pr... 77 1e-13
AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform pr... 77 1e-13
AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform pr... 77 1e-13
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 77 1e-13
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 77 1e-13
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 77 1e-13
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 77 1e-13
AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-depende... 77 1e-13
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 76 1e-13
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 76 1e-13
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 76 1e-13
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 76 1e-13
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 76 1e-13
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 76 1e-13
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 76 1e-13
BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein. 76 1e-13
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 76 1e-13
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 76 1e-13
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 76 1e-13
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 76 1e-13
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 76 1e-13
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 76 1e-13
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 76 1e-13
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 76 1e-13
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 76 2e-13
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 75 3e-13
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 75 3e-13
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 75 3e-13
AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens ... 75 3e-13
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 75 3e-13
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 75 3e-13
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 75 3e-13
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 75 3e-13
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 75 3e-13
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 75 3e-13
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 75 3e-13
D50927-1|BAA09486.2| 801|Homo sapiens KIAA0137 protein protein. 75 3e-13
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 75 3e-13
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 75 3e-13
BC032657-1|AAH32657.1| 766|Homo sapiens tousled-like kinase 1 p... 75 3e-13
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 75 3e-13
AF246219-1|AAF71263.1| 549|Homo sapiens SNARE protein kinase SN... 75 3e-13
AF162666-1|AAF03094.1| 718|Homo sapiens tousled-like kinase 1 p... 75 3e-13
AC010092-1|AAY15077.1| 376|Homo sapiens unknown protein. 75 3e-13
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 75 3e-13
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 75 3e-13
AB209055-1|BAD92292.1| 272|Homo sapiens phosphorylase kinase, g... 75 3e-13
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 75 3e-13
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 75 4e-13
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 75 4e-13
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 74 8e-13
L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-depend... 74 8e-13
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 74 8e-13
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 74 8e-13
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 74 8e-13
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 74 8e-13
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 74 8e-13
BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein. 74 8e-13
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 74 8e-13
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 74 8e-13
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 74 8e-13
AL713896-5|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 74 8e-13
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 74 8e-13
AL713896-3|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 74 8e-13
AL713896-2|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 74 8e-13
AL713896-1|CAI13787.1| 453|Homo sapiens calcium/calmodulin-depe... 74 8e-13
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 74 8e-13
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 74 8e-13
AL596247-5|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 74 8e-13
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 74 8e-13
AL596247-3|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 74 8e-13
AL596247-2|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 74 8e-13
AL596247-1|CAI13964.1| 453|Homo sapiens calcium/calmodulin-depe... 74 8e-13
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 74 8e-13
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 74 8e-13
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 74 8e-13
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 74 8e-13
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 74 8e-13
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 74 8e-13
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 73 1e-12
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 73 1e-12
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 73 1e-12
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 73 1e-12
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 73 2e-12
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 73 2e-12
BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein. 73 2e-12
AK075048-1|BAC11371.1| 434|Homo sapiens protein ( Homo sapiens ... 73 2e-12
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 73 2e-12
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 73 2e-12
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 72 2e-12
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 72 2e-12
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 72 2e-12
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 72 2e-12
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 72 2e-12
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 72 2e-12
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 72 2e-12
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 72 2e-12
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 72 2e-12
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 72 2e-12
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 72 2e-12
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 72 2e-12
BC007835-1|AAH07835.2| 435|Homo sapiens STK40 protein protein. 72 3e-12
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 72 3e-12
AY198395-1|AAP20040.1| 435|Homo sapiens Ser/Thr-like kinase pro... 72 3e-12
AL834498-1|CAD39156.1| 716|Homo sapiens hypothetical protein pr... 72 3e-12
AL591845-6|CAH71864.1| 417|Homo sapiens serine/threonine kinase... 72 3e-12
AL591845-5|CAH71863.1| 440|Homo sapiens serine/threonine kinase... 72 3e-12
AL591845-4|CAH71862.1| 435|Homo sapiens serine/threonine kinase... 72 3e-12
AK075029-1|BAC11361.1| 307|Homo sapiens protein ( Homo sapiens ... 72 3e-12
AK024504-1|BAB15794.1| 419|Homo sapiens FLJ00113 protein protein. 72 3e-12
AF162667-1|AAF03095.1| 749|Homo sapiens tousled-like kinase 2 p... 72 3e-12
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 72 3e-12
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 72 3e-12
AC093748-1|AAY40983.1| 443|Homo sapiens unknown protein. 72 3e-12
AB209181-1|BAD92418.1| 796|Homo sapiens Hypothetical protein DK... 72 3e-12
Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma pr... 71 4e-12
X75756-1|CAA53384.1| 912|Homo sapiens protein kinase C mu protein. 71 4e-12
DQ485452-1|ABE96833.1| 914|Homo sapiens protein kinase D1 protein. 71 4e-12
BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma... 71 4e-12
BC044925-1|AAH44925.2| 830|Homo sapiens TLK2 protein protein. 71 4e-12
AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma ... 71 4e-12
AB004884-1|BAA20561.1| 719|Homo sapiens PKU-alpha protein. 71 4e-12
Z98752-8|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 71 5e-12
Z98752-7|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 71 5e-12
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 71 5e-12
U43784-1|AAC50428.1| 382|Homo sapiens mitogen activated protein... 71 5e-12
U09578-1|AAD09136.1| 382|Homo sapiens MAPKAP kinase protein. 71 5e-12
L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein. 71 5e-12
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 71 5e-12
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 71 5e-12
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 71 5e-12
BC010407-1|AAH10407.1| 382|Homo sapiens mitogen-activated prote... 71 5e-12
BC007591-1|AAH07591.1| 382|Homo sapiens mitogen-activated prote... 71 5e-12
BC001662-1|AAH01662.1| 382|Homo sapiens mitogen-activated prote... 71 5e-12
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 71 5e-12
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 71 5e-12
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 71 5e-12
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 71 5e-12
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 71 5e-12
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 71 5e-12
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 71 5e-12
AL390029-2|CAI15721.1| 740|Homo sapiens doublecortin and CaM ki... 71 7e-12
AL390029-1|CAI15720.1| 729|Homo sapiens doublecortin and CaM ki... 71 7e-12
AL160392-2|CAH70261.1| 740|Homo sapiens doublecortin and CaM ki... 71 7e-12
AL160392-1|CAH70262.1| 729|Homo sapiens doublecortin and CaM ki... 71 7e-12
AL157760-4|CAH70170.1| 433|Homo sapiens doublecortin and CaM ki... 71 7e-12
AL157760-2|CAH70167.1| 740|Homo sapiens doublecortin and CaM ki... 71 7e-12
AL157760-1|CAH70168.1| 729|Homo sapiens doublecortin and CaM ki... 71 7e-12
AL157694-2|CAH70656.1| 740|Homo sapiens doublecortin and CaM ki... 71 7e-12
AL157694-1|CAH70657.1| 729|Homo sapiens doublecortin and CaM ki... 71 7e-12
AB002367-1|BAA20824.2| 794|Homo sapiens KIAA0369 protein. 71 7e-12
X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for ... 70 1e-11
M95712-1|AAA35609.2| 766|Homo sapiens B-raf protein protein. 70 1e-11
M21001-1|AAA96495.1| 328|Homo sapiens B-raf protein protein. 70 1e-11
BC112079-1|AAI12080.1| 766|Homo sapiens v-raf murine sarcoma vi... 70 1e-11
BC101757-1|AAI01758.1| 766|Homo sapiens v-raf murine sarcoma vi... 70 1e-11
BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia... 70 1e-11
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 70 1e-11
AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia... 70 1e-11
AC006344-3|AAD43193.1| 651|Homo sapiens WUGSC:H_DJ0726N20.3 pro... 70 1e-11
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 70 1e-11
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 70 1e-11
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 70 1e-11
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 70 1e-11
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 70 1e-11
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 70 1e-11
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 70 1e-11
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 70 1e-11
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 70 1e-11
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 70 1e-11
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 70 1e-11
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 69 2e-11
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 69 2e-11
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 69 2e-11
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 69 2e-11
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 69 2e-11
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 69 2e-11
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 69 2e-11
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 69 2e-11
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 69 2e-11
BC013316-1|AAH13316.1| 460|Homo sapiens interleukin-1 receptor-... 69 2e-11
AY730682-1|AAX22228.1| 460|Homo sapiens interleukin-1 receptor ... 69 2e-11
AY340967-1|AAR02363.1| 336|Homo sapiens interleukin-1 receptor-... 69 2e-11
AY340966-1|AAR02362.1| 336|Homo sapiens interleukin-1 receptor-... 69 2e-11
AY340965-1|AAR02361.1| 336|Homo sapiens interleukin-1 receptor-... 69 2e-11
AY340964-1|AAR02360.1| 336|Homo sapiens interleukin-1 receptor-... 69 2e-11
AY340963-1|AAR02359.1| 460|Homo sapiens interleukin-1 receptor-... 69 2e-11
AY340962-1|AAR02358.1| 460|Homo sapiens interleukin-1 receptor-... 69 2e-11
AY186092-1|AAN75440.1| 460|Homo sapiens interleukin-1 receptor-... 69 2e-11
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 69 2e-11
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 69 2e-11
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 69 2e-11
AK000528-1|BAA91232.1| 460|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AF445802-1|AAM15772.1| 460|Homo sapiens interleukin-1 receptor ... 69 2e-11
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 69 2e-11
AF155118-1|AAD42884.1| 460|Homo sapiens putative protein kinase... 69 2e-11
AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein. 69 2e-11
AC007390-1|AAY14817.1| 890|Homo sapiens unknown protein. 69 2e-11
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 69 2e-11
AB015982-1|BAA36514.1| 890|Homo sapiens serine/threonine kinase... 69 2e-11
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 69 2e-11
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 69 2e-11
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 69 2e-11
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 69 2e-11
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 69 2e-11
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 69 2e-11
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 69 2e-11
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 69 2e-11
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 69 2e-11
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 69 2e-11
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 69 2e-11
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 69 3e-11
U12779-1|AAA20851.1| 370|Homo sapiens MAP kinase activated prot... 69 3e-11
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 69 3e-11
CR536608-1|CAO03523.1| 326|Homo sapiens pim-3 oncogene protein. 69 3e-11
BX539320-1|CAO03581.1| 326|Homo sapiens pim-3 oncogene protein. 69 3e-11
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 69 3e-11
BC141855-1|AAI41856.1| 326|Homo sapiens pim-3 oncogene protein. 69 3e-11
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 69 3e-11
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 69 3e-11
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 69 3e-11
BC052584-1|AAH52584.1| 400|Homo sapiens mitogen-activated prote... 69 3e-11
BC036060-1|AAH36060.2| 400|Homo sapiens mitogen-activated prote... 69 3e-11
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 69 3e-11
BC015472-1|AAH15472.1| 363|Homo sapiens PRKD2 protein protein. 69 3e-11
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 69 3e-11
AL591846-12|CAI13544.1| 400|Homo sapiens mitogen-activated prot... 69 3e-11
AL591846-11|CAI13543.1| 370|Homo sapiens mitogen-activated prot... 69 3e-11
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 69 3e-11
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 69 3e-11
AK075266-1|BAC11508.1| 721|Homo sapiens protein ( Homo sapiens ... 69 3e-11
AK074673-1|BAC11127.1| 721|Homo sapiens protein ( Homo sapiens ... 69 3e-11
AF309082-1|AAK01149.1| 878|Homo sapiens protein kinase D2 protein. 69 3e-11
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 69 3e-11
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 69 3e-11
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 69 3e-11
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 69 3e-11
AB114795-1|BAD42438.1| 326|Homo sapiens serine/threonine kinase... 69 3e-11
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 69 3e-11
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 68 4e-11
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 68 4e-11
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 68 4e-11
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 68 4e-11
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 68 4e-11
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 68 4e-11
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 68 4e-11
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 68 5e-11
M14503-1|AAA36518.1| 145|Homo sapiens protein ( Human protein-s... 68 5e-11
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 68 5e-11
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 68 5e-11
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 68 5e-11
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 68 5e-11
AK027301-1|BAD12234.1| 277|Homo sapiens protein ( Homo sapiens ... 68 5e-11
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 68 5e-11
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 68 5e-11
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 68 5e-11
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 67 7e-11
X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein ... 67 7e-11
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 67 7e-11
CR536581-1|CAG38818.1| 429|Homo sapiens SGKL protein. 67 7e-11
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 67 7e-11
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 67 7e-11
BC015326-1|AAH15326.1| 496|Homo sapiens serum/glucocorticoid re... 67 7e-11
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 67 7e-11
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 67 7e-11
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 67 7e-11
AL590822-9|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 67 7e-11
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 67 7e-11
AK223523-1|BAD97243.1| 496|Homo sapiens serum/glucocorticoid re... 67 7e-11
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 67 7e-11
AF169035-1|AAF12758.1| 429|Homo sapiens protein kinase protein. 67 7e-11
AF085233-1|AAF27051.2| 496|Homo sapiens SGK-like protein SGKL p... 67 7e-11
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 67 7e-11
U77735-1|AAC78506.1| 334|Homo sapiens pim-2 protooncogene homol... 67 9e-11
BC018111-1|AAH18111.1| 311|Homo sapiens pim-2 oncogene protein. 67 9e-11
AB042425-1|BAA95613.1| 311|Homo sapiens pim-2 protooncogene hom... 67 9e-11
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 66 1e-10
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 66 1e-10
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 66 1e-10
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 66 1e-10
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 66 1e-10
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 66 1e-10
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 66 1e-10
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 66 1e-10
BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein. 66 1e-10
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 66 1e-10
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 66 1e-10
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 66 1e-10
AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase, cAMP-d... 66 1e-10
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 66 1e-10
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 66 1e-10
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 66 1e-10
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 66 1e-10
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 66 1e-10
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 66 1e-10
AB051552-1|BAB21856.1| 608|Homo sapiens KIAA1765 protein protein. 66 1e-10
AK131512-1|BAD18656.1| 345|Homo sapiens protein ( Homo sapiens ... 48 1e-10
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 66 2e-10
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 66 2e-10
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 66 2e-10
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 66 2e-10
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 66 2e-10
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 66 2e-10
BC008344-1|AAH08344.1| 233|Homo sapiens STK40 protein protein. 66 2e-10
BC005169-1|AAH05169.3| 239|Homo sapiens STK40 protein protein. 66 2e-10
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 66 2e-10
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 66 2e-10
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 66 2e-10
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 66 2e-10
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 66 2e-10
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 66 2e-10
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 66 2e-10
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 66 2e-10
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 66 2e-10
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 66 2e-10
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 66 2e-10
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 66 2e-10
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 66 2e-10
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 66 2e-10
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 66 2e-10
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 66 2e-10
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 66 2e-10
>CR456587-1|CAG30473.1| 358|Homo sapiens STK22A protein.
Length = 358
Score = 162 bits (394), Expect = 1e-39
Identities = 69/151 (45%), Positives = 109/151 (72%), Gaps = 2/151 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+++ ++ HRD+KCENLL+D NIKLSDFGF++ ++ NG LS+TFCGS AYA+
Sbjct: 124 VKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAA 183
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSA 206
PE+L+ +PY+P+ D+WS+GV+LY +V G +P+DD++ ++L+ Q +++V FPR ++
Sbjct: 184 PEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTC 243
Query: 205 ECRKLITRILAP-LKMRVKIPQILADPWLNP 116
EC+ LI R+L P + R+ I +IL+ WL P
Sbjct: 244 ECKDLIYRMLQPDVSQRLHIDEILSHSWLQP 274
Score = 73.7 bits (173), Expect = 8e-13
Identities = 37/100 (37%), Positives = 63/100 (63%)
Frame = -1
Query: 766 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 587
TVL GY++G +G GSYA VK A S+R VA+KII + + P D++++FLPRE++++
Sbjct: 5 TVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDIL 64
Query: 586 KGLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDF 467
+ H ++I+ + ET+ I ++M+ G+ L +F
Sbjct: 65 ATVNHGSIIKTYEIFETSDGRI---YIIMELGVQGDLLEF 101
>BC037781-1|AAH37781.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 162 bits (394), Expect = 1e-39
Identities = 69/151 (45%), Positives = 109/151 (72%), Gaps = 2/151 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+++ ++ HRD+KCENLL+D NIKLSDFGF++ ++ NG LS+TFCGS AYA+
Sbjct: 124 VKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAA 183
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSA 206
PE+L+ +PY+P+ D+WS+GV+LY +V G +P+DD++ ++L+ Q +++V FPR ++
Sbjct: 184 PEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTC 243
Query: 205 ECRKLITRILAP-LKMRVKIPQILADPWLNP 116
EC+ LI R+L P + R+ I +IL+ WL P
Sbjct: 244 ECKDLIYRMLQPDVSQRLHIDEILSHSWLQP 274
Score = 73.7 bits (173), Expect = 8e-13
Identities = 37/100 (37%), Positives = 63/100 (63%)
Frame = -1
Query: 766 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 587
TVL GY++G +G GSYA VK A S+R VA+KII + + P D++++FLPRE++++
Sbjct: 5 TVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDIL 64
Query: 586 KGLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDF 467
+ H ++I+ + ET+ I ++M+ G+ L +F
Sbjct: 65 ATVNHGSIIKTYEIFETSDGRI---YIIMELGVQGDLLEF 101
>AF362953-1|AAK98531.1| 358|Homo sapiens testis specific
serine/threonine kinase 2 protein.
Length = 358
Score = 162 bits (394), Expect = 1e-39
Identities = 69/151 (45%), Positives = 109/151 (72%), Gaps = 2/151 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+++ ++ HRD+KCENLL+D NIKLSDFGF++ ++ NG LS+TFCGS AYA+
Sbjct: 124 VKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAA 183
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSA 206
PE+L+ +PY+P+ D+WS+GV+LY +V G +P+DD++ ++L+ Q +++V FPR ++
Sbjct: 184 PEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTC 243
Query: 205 ECRKLITRILAP-LKMRVKIPQILADPWLNP 116
EC+ LI R+L P + R+ I +IL+ WL P
Sbjct: 244 ECKDLIYRMLQPDVSQRLHIDEILSHSWLQP 274
Score = 73.7 bits (173), Expect = 8e-13
Identities = 37/100 (37%), Positives = 63/100 (63%)
Frame = -1
Query: 766 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 587
TVL GY++G +G GSYA VK A S+R VA+KII + + P D++++FLPRE++++
Sbjct: 5 TVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDIL 64
Query: 586 KGLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDF 467
+ H ++I+ + ET+ I ++M+ G+ L +F
Sbjct: 65 ATVNHGSIIKTYEIFETSDGRI---YIIMELGVQGDLLEF 101
>AB284523-1|BAF41974.1| 358|Homo sapiens testis-specific serine
kinase 2 protein.
Length = 358
Score = 162 bits (394), Expect = 1e-39
Identities = 69/151 (45%), Positives = 109/151 (72%), Gaps = 2/151 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+++ ++ HRD+KCENLL+D NIKLSDFGF++ ++ NG LS+TFCGS AYA+
Sbjct: 124 VKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAA 183
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSA 206
PE+L+ +PY+P+ D+WS+GV+LY +V G +P+DD++ ++L+ Q +++V FPR ++
Sbjct: 184 PEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKNLTC 243
Query: 205 ECRKLITRILAP-LKMRVKIPQILADPWLNP 116
EC+ LI R+L P + R+ I +IL+ WL P
Sbjct: 244 ECKDLIYRMLQPDVSQRLHIDEILSHSWLQP 274
Score = 73.7 bits (173), Expect = 8e-13
Identities = 37/100 (37%), Positives = 63/100 (63%)
Frame = -1
Query: 766 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 587
TVL GY++G +G GSYA VK A S+R VA+KII + + P D++++FLPRE++++
Sbjct: 5 TVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPREMDIL 64
Query: 586 KGLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDF 467
+ H ++I+ + ET+ I ++M+ G+ L +F
Sbjct: 65 ATVNHGSIIKTYEIFETSDGRI---YIIMELGVQGDLLEF 101
>BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine
kinase 1B protein.
Length = 367
Score = 160 bits (388), Expect = 7e-39
Identities = 77/189 (40%), Positives = 124/189 (65%), Gaps = 7/189 (3%)
Frame = -1
Query: 661 IKIISKFQAPGDYLKKFLPR----EIEVVKGLKHENL-IRFLQAIETTHRDIKCENLLMD 497
+ I+ + GD L+ R E E K +L I++ ++ HRD+KC+NLL+D
Sbjct: 86 VYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLD 145
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+ D+WS+GV+
Sbjct: 146 KDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQ 143
LY +V G +P+DD+N ++L+ Q +++V+FPR ++ EC+ LI +L P + R+ I +
Sbjct: 206 LYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDE 265
Query: 142 ILADPWLNP 116
IL+ W+ P
Sbjct: 266 ILSHCWMQP 274
Score = 83.8 bits (198), Expect = 7e-16
Identities = 40/78 (51%), Positives = 55/78 (70%)
Frame = -1
Query: 763 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 584
VL+ GY+LG +G GSYA VK A S+R VAIKII + +AP D+L+KFLPREIE++
Sbjct: 6 VLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILA 65
Query: 583 GLKHENLIRFLQAIETTH 530
L H ++I+ + ET+H
Sbjct: 66 MLNHCSIIKTYEIFETSH 83
>AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific
serine/threonine kinase 1 protein.
Length = 367
Score = 160 bits (388), Expect = 7e-39
Identities = 77/189 (40%), Positives = 124/189 (65%), Gaps = 7/189 (3%)
Frame = -1
Query: 661 IKIISKFQAPGDYLKKFLPR----EIEVVKGLKHENL-IRFLQAIETTHRDIKCENLLMD 497
+ I+ + GD L+ R E E K +L I++ ++ HRD+KC+NLL+D
Sbjct: 86 VYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLD 145
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+ D+WS+GV+
Sbjct: 146 KDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQ 143
LY +V G +P+DD+N ++L+ Q +++V+FPR ++ EC+ LI +L P + R+ I +
Sbjct: 206 LYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDE 265
Query: 142 ILADPWLNP 116
IL+ W+ P
Sbjct: 266 ILSHCWMQP 274
Score = 83.8 bits (198), Expect = 7e-16
Identities = 40/78 (51%), Positives = 55/78 (70%)
Frame = -1
Query: 763 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 584
VL+ GY+LG +G GSYA VK A S+R VAIKII + +AP D+L+KFLPREIE++
Sbjct: 6 VLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILA 65
Query: 583 GLKHENLIRFLQAIETTH 530
L H ++I+ + ET+H
Sbjct: 66 MLNHCSIIKTYEIFETSH 83
>AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine
kinase 1 protein.
Length = 367
Score = 160 bits (388), Expect = 7e-39
Identities = 77/189 (40%), Positives = 124/189 (65%), Gaps = 7/189 (3%)
Frame = -1
Query: 661 IKIISKFQAPGDYLKKFLPR----EIEVVKGLKHENL-IRFLQAIETTHRDIKCENLLMD 497
+ I+ + GD L+ R E E K +L I++ ++ HRD+KC+NLL+D
Sbjct: 86 VYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLD 145
Query: 496 HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVV 317
NIKLSDF F++ ++ +G ALS+TFCGS AYA+PE+L+G+PY+P+ D+WS+GV+
Sbjct: 146 KDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIPYQPKVYDIWSLGVI 205
Query: 316 LYAIVYGRLPFDDTNYTQLLK-QVQNKVSFPREPKVSAECRKLITRILAP-LKMRVKIPQ 143
LY +V G +P+DD+N ++L+ Q +++V+FPR ++ EC+ LI +L P + R+ I +
Sbjct: 206 LYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYHMLQPDVNRRLHIDE 265
Query: 142 ILADPWLNP 116
IL+ W+ P
Sbjct: 266 ILSHCWMQP 274
Score = 83.8 bits (198), Expect = 7e-16
Identities = 40/78 (51%), Positives = 55/78 (70%)
Frame = -1
Query: 763 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 584
VL+ GY+LG +G GSYA VK A S+R VAIKII + +AP D+L+KFLPREIE++
Sbjct: 6 VLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILA 65
Query: 583 GLKHENLIRFLQAIETTH 530
L H ++I+ + ET+H
Sbjct: 66 MLNHCSIIKTYEIFETSH 83
>BC111088-1|AAI11089.1| 252|Homo sapiens TSSK4 protein protein.
Length = 252
Score = 145 bits (352), Expect = 2e-34
Identities = 74/160 (46%), Positives = 100/160 (62%), Gaps = 13/160 (8%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKN------------GVFA- 422
I +L + HRD+K ENLL+D N+K+SDFGFA+ M P N F+
Sbjct: 60 IAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSH 117
Query: 421 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN 242
LS+T+CGS+AYA PEIL+G+PY P SD WSMGV+LY +V LPFDDTN +LL++ Q
Sbjct: 118 LSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQK 177
Query: 241 KVSFPREPKVSAECRKLITRILAPLKMRVKIPQILADPWL 122
+V+FP +S EC+ LI ++L R I I+ D W+
Sbjct: 178 EVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWV 217
>AY461663-1|AAS17971.1| 328|Homo sapiens testis-specific serine
kinase 4 protein.
Length = 328
Score = 145 bits (352), Expect = 2e-34
Identities = 74/160 (46%), Positives = 100/160 (62%), Gaps = 13/160 (8%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKN------------GVFA- 422
I +L + HRD+K ENLL+D N+K+SDFGFA+ M P N F+
Sbjct: 136 IAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSH 193
Query: 421 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN 242
LS+T+CGS+AYA PEIL+G+PY P SD WSMGV+LY +V LPFDDTN +LL++ Q
Sbjct: 194 LSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQK 253
Query: 241 KVSFPREPKVSAECRKLITRILAPLKMRVKIPQILADPWL 122
+V+FP +S EC+ LI ++L R I I+ D W+
Sbjct: 254 EVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWV 293
Score = 84.6 bits (200), Expect = 4e-16
Identities = 40/80 (50%), Positives = 57/80 (71%)
Frame = -1
Query: 766 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 587
++++ +GY +G+ IG GSY +V A + VA+KIISK +A DYL KFLPREI+V+
Sbjct: 18 SLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVM 77
Query: 586 KGLKHENLIRFLQAIETTHR 527
K L+H+ LI F +AIE+T R
Sbjct: 78 KVLRHKYLINFYRAIESTSR 97
>BC035354-1|AAH35354.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 144 bits (348), Expect = 5e-34
Identities = 71/148 (47%), Positives = 100/148 (67%), Gaps = 1/148 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
IR+ HRD+KCEN L+ G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+
Sbjct: 122 IRYCHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAA 177
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAE 203
PE+L+G+P+ + DVWSMGVVLY ++ LPFDDT+ ++L Q Q VSFP +SA+
Sbjct: 178 PEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISAD 237
Query: 202 CRKLITRILAP-LKMRVKIPQILADPWL 122
C+ L+ R+L P + +R I ++ PWL
Sbjct: 238 CQDLLKRLLEPDMILRPSIEEVSWHPWL 265
Score = 81.4 bits (192), Expect = 4e-15
Identities = 34/75 (45%), Positives = 56/75 (74%)
Frame = -1
Query: 760 LESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKG 581
L S+GY LG+TIG G+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRT 64
Query: 580 LKHENLIRFLQAIET 536
L H+N+I+ + +E+
Sbjct: 65 LDHKNIIQVYEMLES 79
>AY048701-1|AAL02128.1| 268|Homo sapiens TSSK3 protein.
Length = 268
Score = 144 bits (348), Expect = 5e-34
Identities = 71/148 (47%), Positives = 100/148 (67%), Gaps = 1/148 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
IR+ HRD+KCEN L+ G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+
Sbjct: 122 IRYCHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAA 177
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAE 203
PE+L+G+P+ + DVWSMGVVLY ++ LPFDDT+ ++L Q Q VSFP +SA+
Sbjct: 178 PEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISAD 237
Query: 202 CRKLITRILAP-LKMRVKIPQILADPWL 122
C+ L+ R+L P + +R I ++ PWL
Sbjct: 238 CQDLLKRLLEPDMILRPSIEEVSWHPWL 265
Score = 81.4 bits (192), Expect = 4e-15
Identities = 34/75 (45%), Positives = 56/75 (74%)
Frame = -1
Query: 760 LESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKG 581
L S+GY LG+TIG G+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRT 64
Query: 580 LKHENLIRFLQAIET 536
L H+N+I+ + +E+
Sbjct: 65 LDHKNIIQVYEMLES 79
>AL109945-4|CAI22888.1| 268|Homo sapiens testis-specific serine
kinase 3 protein.
Length = 268
Score = 144 bits (348), Expect = 5e-34
Identities = 71/148 (47%), Positives = 100/148 (67%), Gaps = 1/148 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
IR+ HRD+KCEN L+ G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+
Sbjct: 122 IRYCHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAA 177
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAE 203
PE+L+G+P+ + DVWSMGVVLY ++ LPFDDT+ ++L Q Q VSFP +SA+
Sbjct: 178 PEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISAD 237
Query: 202 CRKLITRILAP-LKMRVKIPQILADPWL 122
C+ L+ R+L P + +R I ++ PWL
Sbjct: 238 CQDLLKRLLEPDMILRPSIEEVSWHPWL 265
Score = 81.4 bits (192), Expect = 4e-15
Identities = 34/75 (45%), Positives = 56/75 (74%)
Frame = -1
Query: 760 LESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKG 581
L S+GY LG+TIG G+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRT 64
Query: 580 LKHENLIRFLQAIET 536
L H+N+I+ + +E+
Sbjct: 65 LDHKNIIQVYEMLES 79
>AF296450-1|AAK97141.1| 268|Homo sapiens testis-specific
serine/threonine kinase 3 protein.
Length = 268
Score = 144 bits (348), Expect = 5e-34
Identities = 71/148 (47%), Positives = 100/148 (67%), Gaps = 1/148 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
IR+ HRD+KCEN L+ G N+KL+DFGFA+ + PK+ LS+TFCGS AYA+
Sbjct: 122 IRYCHGCGVAHRDLKCENALLQ-GFNLKLTDFGFAK--VLPKSHR-ELSQTFCGSTAYAA 177
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAE 203
PE+L+G+P+ + DVWSMGVVLY ++ LPFDDT+ ++L Q Q VSFP +SA+
Sbjct: 178 PEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISAD 237
Query: 202 CRKLITRILAP-LKMRVKIPQILADPWL 122
C+ L+ R+L P + +R I ++ PWL
Sbjct: 238 CQDLLKRLLEPDMILRPSIEEVSWHPWL 265
Score = 81.4 bits (192), Expect = 4e-15
Identities = 34/75 (45%), Positives = 56/75 (74%)
Frame = -1
Query: 760 LESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKG 581
L S+GY LG+TIG G+Y+ VK A S +H +VAIK+I K P +++++FLPRE+++V+
Sbjct: 5 LLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRT 64
Query: 580 LKHENLIRFLQAIET 536
L H+N+I+ + +E+
Sbjct: 65 LDHKNIIQVYEMLES 79
>AK131042-1|BAC85482.1| 338|Homo sapiens protein ( Homo sapiens
cDNA FLJ29008 fis, clone TST06032. ).
Length = 338
Score = 142 bits (344), Expect = 1e-33
Identities = 72/159 (45%), Positives = 99/159 (62%), Gaps = 13/159 (8%)
Frame = -1
Query: 559 RFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKN------------GVFA-L 419
R + ++ RD+K ENLL+D N+K+SDFGFA+ M P N F+ L
Sbjct: 147 RLMPSLSAAGRDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQVNCFSHL 204
Query: 418 SETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK 239
S+T+CGS+AYA PEIL+G+PY P SD WSMGV+LY +V LPFDDTN +LL++ Q +
Sbjct: 205 SQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKE 264
Query: 238 VSFPREPKVSAECRKLITRILAPLKMRVKIPQILADPWL 122
V+FP +S EC+ LI ++L R I I+ D W+
Sbjct: 265 VTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWV 303
Score = 84.6 bits (200), Expect = 4e-16
Identities = 40/80 (50%), Positives = 57/80 (71%)
Frame = -1
Query: 766 TVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVV 587
++++ +GY +G+ IG GSY +V A + VA+KIISK +A DYL KFLPREI+V+
Sbjct: 18 SLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVM 77
Query: 586 KGLKHENLIRFLQAIETTHR 527
K L+H+ LI F +AIE+T R
Sbjct: 78 KVLRHKYLINFYRAIESTSR 97
>AF542390-1|AAN62841.1| 258|Homo sapiens AT03158-like protein
protein.
Length = 258
Score = 142 bits (343), Expect = 2e-33
Identities = 74/166 (44%), Positives = 101/166 (60%), Gaps = 13/166 (7%)
Frame = -1
Query: 580 LKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKN----------- 434
LK L + ++ RD+K ENLL+D N+K+SDFGFA+ M P N
Sbjct: 60 LKLSPLPSLMPSLSAAGRDLKLENLLLDKWENVKISDFGFAK--MVPSNQPVGCSPSYRQ 117
Query: 433 -GVFA-LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQL 260
F+ LS+T+CGS+AYA PEIL+G+PY P SD WSMGV+LY +V LPFDDTN +L
Sbjct: 118 VNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKL 177
Query: 259 LKQVQNKVSFPREPKVSAECRKLITRILAPLKMRVKIPQILADPWL 122
L++ Q +V+FP +S EC+ LI ++L R I I+ D W+
Sbjct: 178 LRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWV 223
>AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 758
Score = 126 bits (303), Expect = 1e-28
Identities = 89/257 (34%), Positives = 134/257 (52%), Gaps = 31/257 (12%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VA+KII K Q L+K RE+ ++K L H N
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 118
Query: 565 L-------------------IRFLQAIETT---------HRDIKCENLLMDHGLNIKLSD 470
+ +F Q + HRD+K ENLL+D +NIK++D
Sbjct: 119 IGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIAD 178
Query: 469 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 290
FGF+ V +TFCGS YA+PE+ +G Y + DVWS+GV+LY +V G L
Sbjct: 179 FGFSNEFT-----VGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 233
Query: 289 PFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWLN 119
PFD N +L ++V + K P +S +C L+ ++L P+K R + QI+ D W+N
Sbjct: 234 PFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RGSLEQIMKDRWMN 290
Query: 118 PNQQSKHDETDLQEHAK 68
H+E +L+ + +
Sbjct: 291 VG----HEEEELKPYTE 303
>AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein.
Length = 870
Score = 126 bits (303), Expect = 1e-28
Identities = 89/257 (34%), Positives = 134/257 (52%), Gaps = 31/257 (12%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VA+KII K Q L+K RE+ ++K L H N
Sbjct: 172 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 230
Query: 565 L-------------------IRFLQAIETT---------HRDIKCENLLMDHGLNIKLSD 470
+ +F Q + HRD+K ENLL+D +NIK++D
Sbjct: 231 IGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIAD 290
Query: 469 FGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRL 290
FGF+ V +TFCGS YA+PE+ +G Y + DVWS+GV+LY +V G L
Sbjct: 291 FGFSNEFT-----VGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL 345
Query: 289 PFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRILA--PLKMRVKIPQILADPWLN 119
PFD N +L ++V + K P +S +C L+ ++L P+K R + QI+ D W+N
Sbjct: 346 PFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLLVLNPIK-RGSLEQIMKDRWMN 402
Query: 118 PNQQSKHDETDLQEHAK 68
H+E +L+ + +
Sbjct: 403 VG----HEEEELKPYTE 415
>BC014611-1|AAH14611.1| 273|Homo sapiens testis-specific serine
kinase 6 protein.
Length = 273
Score = 120 bits (289), Expect = 7e-27
Identities = 63/149 (42%), Positives = 89/149 (59%), Gaps = 2/149 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHG-LNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYA 386
+R+L HRD+KCEN+L+ +KL+DFGF R +G LS T+CGS AYA
Sbjct: 123 VRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYA 178
Query: 385 SPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSA 206
SPE+L G+PY P+ DVWSMGVVLY +V G +PFDD++ L ++ + V +P ++S
Sbjct: 179 SPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSE 238
Query: 205 ECRKLITRILA-PLKMRVKIPQILADPWL 122
C+ LI +L R Q+ + WL
Sbjct: 239 RCKALIAELLQFSPSARPSAGQVARNCWL 267
Score = 82.2 bits (194), Expect = 2e-15
Identities = 34/75 (45%), Positives = 55/75 (73%)
Frame = -1
Query: 763 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 584
+L GY LGRTIG GSY+ VKVA+S ++ VAIK++ + +AP D++ KFLPRE+ +++
Sbjct: 6 LLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILR 65
Query: 583 GLKHENLIRFLQAIE 539
G++H +++ + IE
Sbjct: 66 GVRHPHIVHVFEFIE 80
>AF329483-1|AAK48827.1| 273|Homo sapiens serine/threonine protein
kinase SSTK protein.
Length = 273
Score = 120 bits (289), Expect = 7e-27
Identities = 63/149 (42%), Positives = 89/149 (59%), Gaps = 2/149 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHG-LNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYA 386
+R+L HRD+KCEN+L+ +KL+DFGF R +G LS T+CGS AYA
Sbjct: 123 VRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYA 178
Query: 385 SPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSA 206
SPE+L G+PY P+ DVWSMGVVLY +V G +PFDD++ L ++ + V +P ++S
Sbjct: 179 SPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSE 238
Query: 205 ECRKLITRILA-PLKMRVKIPQILADPWL 122
C+ LI +L R Q+ + WL
Sbjct: 239 RCKALIAELLQFSPSARPSAGQVARNCWL 267
Score = 82.2 bits (194), Expect = 2e-15
Identities = 34/75 (45%), Positives = 55/75 (73%)
Frame = -1
Query: 763 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 584
+L GY LGRTIG GSY+ VKVA+S ++ VAIK++ + +AP D++ KFLPRE+ +++
Sbjct: 6 LLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILR 65
Query: 583 GLKHENLIRFLQAIE 539
G++H +++ + IE
Sbjct: 66 GVRHPHIVHVFEFIE 80
>AK172841-1|BAD18805.1| 406|Homo sapiens protein ( Homo sapiens
cDNA FLJ24002 fis, clone KAIA4350, highly similar to
Homo sapiens serine/threonine protein kinase SSTK
(SSTK). ).
Length = 406
Score = 118 bits (285), Expect = 2e-26
Identities = 61/142 (42%), Positives = 88/142 (61%), Gaps = 3/142 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHG-LNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYA 386
+R+L HRD+KCEN+L+ +KL+DFGF R +G LS T+CGS AYA
Sbjct: 123 VRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGR----QAHGYPDLSTTYCGSAAYA 178
Query: 385 SPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSA 206
SPE+L G+PY P+ DVWSMGVVLY +V G +PFDD++ L ++ + V +P ++S
Sbjct: 179 SPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSE 238
Query: 205 ECRKLITRILA--PLKMRVKIP 146
C+ LI A P++ ++ P
Sbjct: 239 RCKALIAEAAAVQPVRQALRGP 260
Score = 82.2 bits (194), Expect = 2e-15
Identities = 34/75 (45%), Positives = 55/75 (73%)
Frame = -1
Query: 763 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 584
+L GY LGRTIG GSY+ VKVA+S ++ VAIK++ + +AP D++ KFLPRE+ +++
Sbjct: 6 LLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILR 65
Query: 583 GLKHENLIRFLQAIE 539
G++H +++ + IE
Sbjct: 66 GVRHPHIVHVFEFIE 80
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 111 bits (266), Expect = 4e-24
Identities = 63/164 (38%), Positives = 96/164 (58%), Gaps = 3/164 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+++ HRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA+
Sbjct: 166 VQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT-----VGGKLDTFCGSPPYAA 220
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSA 206
PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P +S
Sbjct: 221 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMST 278
Query: 205 ECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 80
+C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 279 DCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 317
Score = 60.5 bits (140), Expect = 8e-09
Identities = 39/103 (37%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VAIKII K Q L+K L RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHPN 114
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ A G MK K
Sbjct: 115 IVKLFEVIETE----KTLYLIMEYASGGEVFDYLVAHGRMKEK 153
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 111 bits (266), Expect = 4e-24
Identities = 63/164 (38%), Positives = 96/164 (58%), Gaps = 3/164 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+++ HRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA+
Sbjct: 166 VQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT-----VGGKLDTFCGSPPYAA 220
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSA 206
PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P +S
Sbjct: 221 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMST 278
Query: 205 ECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 80
+C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 279 DCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 317
Score = 62.1 bits (144), Expect = 3e-09
Identities = 40/103 (38%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VAIKII K Q L+K L RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHPN 114
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ K+ D+ A G MK K
Sbjct: 115 IVKLFEVIETQ----KTLYLIMEYASGGKVFDYLVAHGRMKEK 153
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 111 bits (266), Expect = 4e-24
Identities = 63/164 (38%), Positives = 96/164 (58%), Gaps = 3/164 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+++ HRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA+
Sbjct: 166 VQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT-----VGGKLDTFCGSPPYAA 220
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSA 206
PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P +S
Sbjct: 221 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMST 278
Query: 205 ECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 80
+C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 279 DCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 317
Score = 60.5 bits (140), Expect = 8e-09
Identities = 39/103 (37%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VAIKII K Q L+K L RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHPN 114
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ A G MK K
Sbjct: 115 IVKLFEVIETE----KTLYLIMEYASGGEVFDYLVAHGRMKEK 153
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 111 bits (266), Expect = 4e-24
Identities = 63/164 (38%), Positives = 96/164 (58%), Gaps = 3/164 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+++ HRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA+
Sbjct: 166 VQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT-----VGGKLDTFCGSPPYAA 220
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSA 206
PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P +S
Sbjct: 221 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMST 278
Query: 205 ECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 80
+C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 279 DCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 317
Score = 62.1 bits (144), Expect = 3e-09
Identities = 40/103 (38%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VAIKII K Q L+K L RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHPN 114
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ K+ D+ A G MK K
Sbjct: 115 IVKLFEVIETE----KTLYLIMEYASGGKVFDYLVAHGRMKEK 153
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 111 bits (266), Expect = 4e-24
Identities = 63/164 (38%), Positives = 96/164 (58%), Gaps = 3/164 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+++ HRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA+
Sbjct: 166 VQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT-----VGGKLDTFCGSPPYAA 220
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSA 206
PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P +S
Sbjct: 221 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMST 278
Query: 205 ECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 80
+C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 279 DCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 317
Score = 60.5 bits (140), Expect = 8e-09
Identities = 39/103 (37%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VAIKII K Q L+K L RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHPN 114
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ A G MK K
Sbjct: 115 IVKLFEVIETE----KTLYLIMEYASGGEVFDYLVAHGRMKEK 153
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 111 bits (266), Expect = 4e-24
Identities = 63/164 (38%), Positives = 96/164 (58%), Gaps = 3/164 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+++ HRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA+
Sbjct: 189 VQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT-----VGGKLDTFCGSPPYAA 243
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSA 206
PE+ +G Y + DVWS+GV+LY +V G LPFD N +L ++V + K P +S
Sbjct: 244 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMST 301
Query: 205 ECRKLITR--ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQ 80
+C L+ R +L P+K R + QI+ D W+N + H+E +L+
Sbjct: 302 DCENLLKRFLVLNPIK-RGTLEQIMKDRWIN----AGHEEDELK 340
Score = 60.1 bits (139), Expect = 1e-08
Identities = 39/103 (37%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VAIKII K Q L+K L RE+ ++K L H N
Sbjct: 56 YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-LFREVRIMKILNHPN 114
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ A G MK K
Sbjct: 115 IVKLFEVIETE----KTLYLIMEYASGGEVFDYLVAHGKMKEK 153
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 109 bits (263), Expect = 1e-23
Identities = 62/158 (39%), Positives = 94/158 (59%), Gaps = 3/158 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA+PE+ +G Y
Sbjct: 180 HRDLKAENLLLDGDMNIKIADFGFSNEFT-----VGNKLDTFCGSPPYAAPELFQGKKYD 234
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLL 292
Query: 175 A--PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 68
P+K R + QI+ D W+N H+E +L+ + +
Sbjct: 293 VLNPIK-RGSLEQIMKDRWMNVG----HEEEELKPYTE 325
Score = 60.5 bits (140), Expect = 8e-09
Identities = 38/103 (36%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VA+KII K Q L+K L RE+ ++K L H N
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQK-LFREVRIMKILNHPN 118
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ A G MK K
Sbjct: 119 IVKLFEVIETE----KTLYLVMEYASGGEVFDYLVAHGRMKEK 157
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 109 bits (263), Expect = 1e-23
Identities = 62/158 (39%), Positives = 94/158 (59%), Gaps = 3/158 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA+PE+ +G Y
Sbjct: 180 HRDLKAENLLLDGDMNIKIADFGFSNEFT-----VGNKLDTFCGSPPYAAPELFQGKKYD 234
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLL 292
Query: 175 A--PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 68
P+K R + QI+ D W+N H+E +L+ + +
Sbjct: 293 VLNPIK-RGSLEQIMKDRWMNVG----HEEEELKPYTE 325
Score = 60.5 bits (140), Expect = 8e-09
Identities = 38/103 (36%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VA+KII K Q L+K L RE+ ++K L H N
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQK-LFREVRIMKILNHPN 118
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ A G MK K
Sbjct: 119 IVKLFEVIETE----KTLYLVMEYASGGEVFDYLVAHGRMKEK 157
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 109 bits (263), Expect = 1e-23
Identities = 62/158 (39%), Positives = 94/158 (59%), Gaps = 3/158 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA+PE+ +G Y
Sbjct: 180 HRDLKAENLLLDGDMNIKIADFGFSNEFT-----VGNKLDTFCGSPPYAAPELFQGKKYD 234
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLL 292
Query: 175 A--PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 68
P+K R + QI+ D W+N H+E +L+ + +
Sbjct: 293 VLNPIK-RGSLEQIMKDRWMNVG----HEEEELKPYTE 325
Score = 60.5 bits (140), Expect = 8e-09
Identities = 38/103 (36%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VA+KII K Q L+K L RE+ ++K L H N
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQK-LFREVRIMKILNHPN 118
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ A G MK K
Sbjct: 119 IVKLFEVIETE----KTLYLVMEYASGGEVFDYLVAHGRMKEK 157
>AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens
cDNA FLJ14587 fis, clone NT2RM4001758, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK
(EC 2.7.1.-). ).
Length = 638
Score = 109 bits (263), Expect = 1e-23
Identities = 62/158 (39%), Positives = 94/158 (59%), Gaps = 3/158 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA+PE+ +G Y
Sbjct: 45 HRDLKAENLLLDGDMNIKIADFGFSNEFT-----VGNKLDTFCGSPPYAAPELFQGKKYD 99
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L
Sbjct: 100 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLL 157
Query: 175 A--PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 68
P+K R + QI+ D W+N H+E +L+ + +
Sbjct: 158 VLNPIK-RGSLEQIMKDRWMNVG----HEEEELKPYTE 190
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 109 bits (263), Expect = 1e-23
Identities = 62/158 (39%), Positives = 94/158 (59%), Gaps = 3/158 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D +NIK++DFGF+ V +TFCGS YA+PE+ +G Y
Sbjct: 180 HRDLKAENLLLDGDMNIKIADFGFSNEFT-----VGNKLDTFCGSPPYAAPELFQGKKYD 234
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ ++L
Sbjct: 235 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKLL 292
Query: 175 A--PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 68
P+K R + QI+ D W+N H+E +L+ + +
Sbjct: 293 VLNPIK-RGSLEQIMKDRWMNVG----HEEEELKPYTE 325
Score = 60.5 bits (140), Expect = 8e-09
Identities = 38/103 (36%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VA+KII K Q L+K L RE+ ++K L H N
Sbjct: 60 YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQK-LFREVRIMKILNHPN 118
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ A G MK K
Sbjct: 119 IVKLFEVIETE----KTLYLVMEYASGGEVFDYLVAHGRMKEK 157
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 108 bits (259), Expect = 3e-23
Identities = 58/150 (38%), Positives = 86/150 (57%), Gaps = 1/150 (0%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K EN+L+D NIK++DFG + + K K +TFCGS YASPEI+ G PYR
Sbjct: 213 HRDLKLENILLDDNCNIKIADFGLSNLYQKDK-----FLQTFCGSPLYASPEIVNGRPYR 267
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLIT-RIL 176
+ D W++GV+LY +VYG +PFD ++ L++Q+ + REP ++ R LI ++
Sbjct: 268 GPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISS--GEYREPTQPSDARGLIRWMLM 325
Query: 175 APLKMRVKIPQILADPWLNPNQQSKHDETD 86
R I I W+N +S + D
Sbjct: 326 VNPDRRATIEDIANHWWVNWGYKSSVCDCD 355
Score = 43.6 bits (98), Expect = 0.001
Identities = 27/95 (28%), Positives = 46/95 (48%)
Frame = -1
Query: 751 HGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKH 572
H Y L T+G G+Y VK A+ VAIK I K + + + REIE++ L H
Sbjct: 90 HRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNH 149
Query: 571 ENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDF 467
++I + E + + ++M++ +L D+
Sbjct: 150 PHIISIYEVFENKDKIV----IIMEYASKGELYDY 180
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 105 bits (253), Expect = 2e-22
Identities = 61/158 (38%), Positives = 92/158 (58%), Gaps = 3/158 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y
Sbjct: 140 HRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYD 194
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ +
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFL 252
Query: 181 ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 68
IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 253 ILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 285
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/103 (36%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VA+KII K Q L+K L RE+ ++K L H N
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHPN 78
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ A G MK K
Sbjct: 79 IVKLFEVIETE----KTLYLVMEYASGGEVFDYLVAHGRMKEK 117
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 105 bits (253), Expect = 2e-22
Identities = 61/158 (38%), Positives = 92/158 (58%), Gaps = 3/158 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y
Sbjct: 140 HRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYD 194
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ +
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFL 252
Query: 181 ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 68
IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 253 ILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 285
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/103 (36%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VA+KII K Q L+K L RE+ ++K L H N
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHPN 78
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ A G MK K
Sbjct: 79 IVKLFEVIETE----KTLYLVMEYASGGEVFDYLVAHGRMKEK 117
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 105 bits (253), Expect = 2e-22
Identities = 61/158 (38%), Positives = 92/158 (58%), Gaps = 3/158 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y
Sbjct: 173 HRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYD 227
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ +
Sbjct: 228 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFL 285
Query: 181 ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 68
IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 286 ILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 318
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/141 (30%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
Frame = -1
Query: 853 THDHVLGEMSAEPTXTVHSGVEAKTERKLTVLESH--GYMLGRTIGSGSYATVKVASSDR 680
T LG + ++P+ + + + + H Y L +TIG G++A VK+A
Sbjct: 16 TEQPTLGHLDSKPSSKSNM-IRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHIL 74
Query: 679 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRDIKCENLLM 500
+VA+KII K Q L+K L RE+ ++K L H N+++ + IET K L+M
Sbjct: 75 TGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHPNIVKLFEVIETE----KTLYLVM 129
Query: 499 DHGLNIKLSDFGFARGHMKPK 437
++ ++ D+ A G MK K
Sbjct: 130 EYASGGEVFDYLVAHGRMKEK 150
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 105 bits (253), Expect = 2e-22
Identities = 61/158 (38%), Positives = 92/158 (58%), Gaps = 3/158 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y
Sbjct: 163 HRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYD 217
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ +
Sbjct: 218 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFL 275
Query: 181 ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 68
IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 276 ILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 308
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/141 (30%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
Frame = -1
Query: 853 THDHVLGEMSAEPTXTVHSGVEAKTERKLTVLESH--GYMLGRTIGSGSYATVKVASSDR 680
T LG + ++P+ + + + + H Y L +TIG G++A VK+A
Sbjct: 6 TEQPTLGHLDSKPSSKSNM-IRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHIL 64
Query: 679 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRDIKCENLLM 500
+VA+KII K Q L+K L RE+ ++K L H N+++ + IET K L+M
Sbjct: 65 TGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHPNIVKLFEVIETE----KTLYLVM 119
Query: 499 DHGLNIKLSDFGFARGHMKPK 437
++ ++ D+ A G MK K
Sbjct: 120 EYASGGEVFDYLVAHGRMKEK 140
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 105 bits (253), Expect = 2e-22
Identities = 61/158 (38%), Positives = 92/158 (58%), Gaps = 3/158 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y
Sbjct: 140 HRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYD 194
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ +
Sbjct: 195 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFL 252
Query: 181 ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 68
IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 253 ILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 285
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/103 (36%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +TIG G++A VK+A +VA+KII K Q L+K L RE+ ++K L H N
Sbjct: 20 YRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHPN 78
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ A G MK K
Sbjct: 79 IVKLFEVIETE----KTLYLVMEYASGGEVFDYLVAHGRMKEK 117
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 105 bits (253), Expect = 2e-22
Identities = 61/158 (38%), Positives = 92/158 (58%), Gaps = 3/158 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D +NIK++DFGF+ +TFCGS YA+PE+ +G Y
Sbjct: 173 HRDLKAENLLLDADMNIKIADFGFSNEFTFGNK-----LDTFCGSPPYAAPELFQGKKYD 227
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ DVWS+GV+LY +V G LPFD N +L ++V + K P +S +C L+ +
Sbjct: 228 GPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF--YMSTDCENLLKKFL 285
Query: 181 ILAPLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAK 68
IL P K R + QI+ D W+N H++ +L+ + +
Sbjct: 286 ILNPSK-RGTLEQIMKDRWMNVG----HEDDELKPYVE 318
Score = 61.7 bits (143), Expect = 3e-09
Identities = 43/141 (30%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
Frame = -1
Query: 853 THDHVLGEMSAEPTXTVHSGVEAKTERKLTVLESH--GYMLGRTIGSGSYATVKVASSDR 680
T LG + ++P+ + + + + H Y L +TIG G++A VK+A
Sbjct: 16 TEQPTLGHLDSKPSSKSNM-IRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHIL 74
Query: 679 HNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTHRDIKCENLLM 500
+VA+KII K Q L+K L RE+ ++K L H N+++ + IET K L+M
Sbjct: 75 TGKEVAVKIIDKTQLNSSSLQK-LFREVRIMKVLNHPNIVKLFEVIETE----KTLYLVM 129
Query: 499 DHGLNIKLSDFGFARGHMKPK 437
++ ++ D+ A G MK K
Sbjct: 130 EYASGGEVFDYLVAHGRMKEK 150
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 105 bits (251), Expect = 3e-22
Identities = 57/141 (40%), Positives = 85/141 (60%), Gaps = 3/141 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D NIK++DFGF+ + + +TFCGS YA+PE+ +G Y
Sbjct: 179 HRDLKAENLLLDAEANIKIADFGFSNEFT-----LGSKLDTFCGSPPYAAPELFQGKKYD 233
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ D+WS+GV+LY +V G LPFD N +L ++V + K P +S +C ++ R
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFL 291
Query: 181 ILAPLKMRVKIPQILADPWLN 119
+L P K R + QI+ D W+N
Sbjct: 292 VLNPAK-RCTLEQIMKDKWIN 311
Score = 63.7 bits (148), Expect = 8e-10
Identities = 40/103 (38%), Positives = 59/103 (57%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L RTIG G++A VK+A +VAIKII K Q L+K L RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHPN 117
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ + G MK K
Sbjct: 118 IVKLFEVIETE----KTLYLVMEYASAGEVFDYLVSHGRMKEK 156
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 105 bits (251), Expect = 3e-22
Identities = 57/141 (40%), Positives = 85/141 (60%), Gaps = 3/141 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D NIK++DFGF+ + + +TFCGS YA+PE+ +G Y
Sbjct: 179 HRDLKAENLLLDAEANIKIADFGFSNEFT-----LGSKLDTFCGSPPYAAPELFQGKKYD 233
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ D+WS+GV+LY +V G LPFD N +L ++V + K P +S +C ++ R
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFL 291
Query: 181 ILAPLKMRVKIPQILADPWLN 119
+L P K R + QI+ D W+N
Sbjct: 292 VLNPAK-RCTLEQIMKDKWIN 311
Score = 63.7 bits (148), Expect = 8e-10
Identities = 40/103 (38%), Positives = 59/103 (57%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L RTIG G++A VK+A +VAIKII K Q L+K L RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHPN 117
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ + G MK K
Sbjct: 118 IVKLFEVIETE----KTLYLVMEYASAGEVFDYLVSHGRMKEK 156
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 105 bits (251), Expect = 3e-22
Identities = 57/141 (40%), Positives = 85/141 (60%), Gaps = 3/141 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D NIK++DFGF+ + + +TFCGS YA+PE+ +G Y
Sbjct: 179 HRDLKAENLLLDAEANIKIADFGFSNEFT-----LGSKLDTFCGSPPYAAPELFQGKKYD 233
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ D+WS+GV+LY +V G LPFD N +L ++V + K P +S +C ++ R
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFL 291
Query: 181 ILAPLKMRVKIPQILADPWLN 119
+L P K R + QI+ D W+N
Sbjct: 292 VLNPAK-RCTLEQIMKDKWIN 311
Score = 63.7 bits (148), Expect = 8e-10
Identities = 40/103 (38%), Positives = 59/103 (57%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L RTIG G++A VK+A +VAIKII K Q L+K L RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHPN 117
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ + G MK K
Sbjct: 118 IVKLFEVIETE----KTLYLVMEYASAGEVFDYLVSHGRMKEK 156
>AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens
cDNA FLJ90097 fis, clone HEMBA1005929, weakly similar to
H.sapiens mRNA for serine/threonine protein kinase EMK.
).
Length = 426
Score = 105 bits (251), Expect = 3e-22
Identities = 57/141 (40%), Positives = 85/141 (60%), Gaps = 3/141 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D NIK++DFGF+ + + +TFCGS YA+PE+ +G Y
Sbjct: 45 HRDLKAENLLLDAEANIKIADFGFSNEFT-----LGSKLDTFCGSPPYAAPELFQGKKYD 99
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ D+WS+GV+LY +V G LPFD N +L ++V + K P +S +C ++ R
Sbjct: 100 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFL 157
Query: 181 ILAPLKMRVKIPQILADPWLN 119
+L P K R + QI+ D W+N
Sbjct: 158 VLNPAK-RCTLEQIMKDKWIN 177
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 105 bits (251), Expect = 3e-22
Identities = 57/141 (40%), Positives = 85/141 (60%), Gaps = 3/141 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D NIK++DFGF+ + + +TFCGS YA+PE+ +G Y
Sbjct: 209 HRDLKAENLLLDAEANIKIADFGFSNEFT-----LGSKLDTFCGSPPYAAPELFQGKKYD 263
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ D+WS+GV+LY +V G LPFD N +L ++V + K P +S +C ++ R
Sbjct: 264 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFL 321
Query: 181 ILAPLKMRVKIPQILADPWLN 119
+L P K R + QI+ D W+N
Sbjct: 322 VLNPAK-RCTLEQIMKDKWIN 341
Score = 58.8 bits (136), Expect = 2e-08
Identities = 32/70 (45%), Positives = 44/70 (62%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L RTIG G++A VK+A +VAIKII K Q L+K L RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHPN 117
Query: 565 LIRFLQAIET 536
+++ + IET
Sbjct: 118 IVKLFEVIET 127
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 105 bits (251), Expect = 3e-22
Identities = 57/141 (40%), Positives = 85/141 (60%), Gaps = 3/141 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D NIK++DFGF+ + + +TFCGS YA+PE+ +G Y
Sbjct: 179 HRDLKAENLLLDAEANIKIADFGFSNEFT-----LGSKLDTFCGSPPYAAPELFQGKKYD 233
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ D+WS+GV+LY +V G LPFD N +L ++V + K P +S +C ++ R
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFL 291
Query: 181 ILAPLKMRVKIPQILADPWLN 119
+L P K R + QI+ D W+N
Sbjct: 292 VLNPAK-RCTLEQIMKDKWIN 311
Score = 61.7 bits (143), Expect = 3e-09
Identities = 40/103 (38%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L RTIG G+ A VK+A +VAIKII K Q L+K L RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHPN 117
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ + G MK K
Sbjct: 118 IVKLFEVIETE----KTLYLVMEYASAGEVFDYLVSHGRMKEK 156
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 105 bits (251), Expect = 3e-22
Identities = 57/141 (40%), Positives = 85/141 (60%), Gaps = 3/141 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D NIK++DFGF+ + + +TFCGS YA+PE+ +G Y
Sbjct: 180 HRDLKAENLLLDAEANIKIADFGFSNEFT-----LGSKLDTFCGSPPYAAPELFQGKKYD 234
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ D+WS+GV+LY +V G LPFD N +L ++V + K P +S +C ++ R
Sbjct: 235 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFL 292
Query: 181 ILAPLKMRVKIPQILADPWLN 119
+L P K R + QI+ D W+N
Sbjct: 293 VLNPAK-RCTLEQIMKDKWIN 312
Score = 63.7 bits (148), Expect = 8e-10
Identities = 40/103 (38%), Positives = 59/103 (57%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L RTIG G++A VK+A +VAIKII K Q L+K L RE+ ++KGL H N
Sbjct: 60 YRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHPN 118
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ + G MK K
Sbjct: 119 IVKLFEVIETE----KTLYLVMEYASAGEVFDYLVSHGRMKEK 157
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 105 bits (251), Expect = 3e-22
Identities = 57/141 (40%), Positives = 85/141 (60%), Gaps = 3/141 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D NIK++DFGF+ + + +TFCGS YA+PE+ +G Y
Sbjct: 179 HRDLKAENLLLDAEANIKIADFGFSNEFT-----LGSKLDTFCGSPPYAAPELFQGKKYD 233
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITR-- 182
+ D+WS+GV+LY +V G LPFD N +L ++V + K P +S +C ++ R
Sbjct: 234 GPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPF--YMSTDCESILRRFL 291
Query: 181 ILAPLKMRVKIPQILADPWLN 119
+L P K R + QI+ D W+N
Sbjct: 292 VLNPAK-RCTLEQIMKDKWIN 311
Score = 61.7 bits (143), Expect = 3e-09
Identities = 40/103 (38%), Positives = 58/103 (56%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L RTIG G+ A VK+A +VAIKII K Q L+K L RE+ ++KGL H N
Sbjct: 59 YRLLRTIGKGNSAKVKLARHILTGREVAIKIIDKTQLNPSSLQK-LFREVRIMKGLNHPN 117
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + IET K L+M++ ++ D+ + G MK K
Sbjct: 118 IVKLFEVIETE----KTLYLVMEYASAGEVFDYLVSHGRMKEK 156
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 103 bits (248), Expect = 6e-22
Identities = 52/148 (35%), Positives = 83/148 (56%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ + HRD+K EN+L+D NIK++DFG + + + K +TFCGS YAS
Sbjct: 163 VHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGK-----FLQTFCGSPLYAS 217
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAE 203
PEI+ G PY + D WS+GV+LY +V+G +PFD ++ L+KQ+ N ++ PK S
Sbjct: 218 PEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNG-AYREPPKPSDA 276
Query: 202 CRKLITRILAPLKMRVKIPQILADPWLN 119
C + ++ R + + + W+N
Sbjct: 277 CGLIRWLLMVNPTRRATLEDVASHWWVN 304
Score = 38.3 bits (85), Expect = 0.036
Identities = 23/75 (30%), Positives = 35/75 (46%)
Frame = -1
Query: 751 HGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKH 572
H Y T+G G+Y VK A VAIK I K + + + REIE++ L H
Sbjct: 51 HRYEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNH 109
Query: 571 ENLIRFLQAIETTHR 527
++I + E + +
Sbjct: 110 PHIIAIHEVFENSSK 124
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 103 bits (248), Expect = 6e-22
Identities = 56/145 (38%), Positives = 85/145 (58%), Gaps = 1/145 (0%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 146 FCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 200
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
++KG Y + +D+WS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 201 VIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 259
Query: 196 KLITRIL-APLKMRVKIPQILADPW 125
L+ ++ + R+ + QI PW
Sbjct: 260 SLLRGMIEVEPEKRLSLEQIQKHPW 284
Score = 40.7 bits (91), Expect = 0.007
Identities = 27/103 (26%), Positives = 54/103 (52%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 92
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + + + K L+++H +L D+ +G + PK
Sbjct: 93 VLK----LHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK 131
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 103 bits (248), Expect = 6e-22
Identities = 56/145 (38%), Positives = 85/145 (58%), Gaps = 1/145 (0%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 146 FCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 200
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
++KG Y + +D+WS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 201 VIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 259
Query: 196 KLITRIL-APLKMRVKIPQILADPW 125
L+ ++ + R+ + QI PW
Sbjct: 260 SLLRGMIEVEPEKRLSLEQIQKHPW 284
Score = 40.7 bits (91), Expect = 0.007
Identities = 27/103 (26%), Positives = 54/103 (52%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 92
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + + + K L+++H +L D+ +G + PK
Sbjct: 93 VLK----LHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK 131
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 103 bits (248), Expect = 6e-22
Identities = 52/148 (35%), Positives = 83/148 (56%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ + HRD+K EN+L+D NIK++DFG + + + K +TFCGS YAS
Sbjct: 163 VHYCHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGK-----FLQTFCGSPLYAS 217
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAE 203
PEI+ G PY + D WS+GV+LY +V+G +PFD ++ L+KQ+ N ++ PK S
Sbjct: 218 PEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNG-AYREPPKPSDA 276
Query: 202 CRKLITRILAPLKMRVKIPQILADPWLN 119
C + ++ R + + + W+N
Sbjct: 277 CGLIRWLLMVNPTRRATLEDVASHWWVN 304
Score = 38.3 bits (85), Expect = 0.036
Identities = 23/75 (30%), Positives = 35/75 (46%)
Frame = -1
Query: 751 HGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKH 572
H Y T+G G+Y VK A VAIK I K + + + REIE++ L H
Sbjct: 51 HRYEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDLMHIRREIEIMSSLNH 109
Query: 571 ENLIRFLQAIETTHR 527
++I + E + +
Sbjct: 110 PHIIAIHEVFENSSK 124
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 103 bits (248), Expect = 6e-22
Identities = 56/145 (38%), Positives = 85/145 (58%), Gaps = 1/145 (0%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 146 FCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 200
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
++KG Y + +D+WS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 201 VIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 259
Query: 196 KLITRIL-APLKMRVKIPQILADPW 125
L+ ++ + R+ + QI PW
Sbjct: 260 SLLRGMIEVEPEKRLSLEQIQKHPW 284
Score = 40.7 bits (91), Expect = 0.007
Identities = 27/103 (26%), Positives = 54/103 (52%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 34 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 92
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + + + K L+++H +L D+ +G + PK
Sbjct: 93 VLK----LHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK 131
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 103 bits (248), Expect = 6e-22
Identities = 56/145 (38%), Positives = 85/145 (58%), Gaps = 1/145 (0%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 162 FCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 216
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
++KG Y + +D+WS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 217 VIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 275
Query: 196 KLITRIL-APLKMRVKIPQILADPW 125
L+ ++ + R+ + QI PW
Sbjct: 276 SLLRGMIEVEPEKRLSLEQIQKHPW 300
Score = 40.7 bits (91), Expect = 0.007
Identities = 27/103 (26%), Positives = 54/103 (52%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +T+G G VK+ +VAIKI+++ + L K + REI ++K ++H +
Sbjct: 50 YRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPH 108
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPK 437
+++ + + + K L+++H +L D+ +G + PK
Sbjct: 109 VLK----LHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPK 147
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 103 bits (248), Expect = 6e-22
Identities = 56/145 (38%), Positives = 85/145 (58%), Gaps = 1/145 (0%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 83 FCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 137
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
++KG Y + +D+WS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 138 VIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 196
Query: 196 KLITRIL-APLKMRVKIPQILADPW 125
L+ ++ + R+ + QI PW
Sbjct: 197 SLLRGMIEVEPEKRLSLEQIQKHPW 221
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 101 bits (241), Expect = 4e-21
Identities = 60/139 (43%), Positives = 81/139 (58%), Gaps = 2/139 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y
Sbjct: 140 HRDLKAENLLLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYE 194
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--I 179
D+WSMGVVLY +V G LPFD +L+Q + F +S +C LI R +
Sbjct: 195 GPQLDIWSMGVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLV 253
Query: 178 LAPLKMRVKIPQILADPWL 122
L P K R+ I QI W+
Sbjct: 254 LDPSK-RLTIAQIKEHKWM 271
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/70 (37%), Positives = 42/70 (60%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y + T+G G++A VK+ +VAIKII K Q L+K + RE++++K L H +
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEK-IYREVQIMKMLDHPH 78
Query: 565 LIRFLQAIET 536
+I+ Q +ET
Sbjct: 79 IIKLYQVMET 88
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 101 bits (241), Expect = 4e-21
Identities = 60/139 (43%), Positives = 81/139 (58%), Gaps = 2/139 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y
Sbjct: 140 HRDLKAENLLLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYE 194
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--I 179
D+WSMGVVLY +V G LPFD +L+Q + F +S +C LI R +
Sbjct: 195 GPQLDIWSMGVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLV 253
Query: 178 LAPLKMRVKIPQILADPWL 122
L P K R+ I QI W+
Sbjct: 254 LDPSK-RLTIAQIKEHKWM 271
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/70 (37%), Positives = 42/70 (60%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y + T+G G++A VK+ +VAIKII K Q L+K + RE++++K L H +
Sbjct: 20 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEK-IYREVQIMKMLDHPH 78
Query: 565 LIRFLQAIET 536
+I+ Q +ET
Sbjct: 79 IIKLYQVMET 88
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 101 bits (241), Expect = 4e-21
Identities = 60/139 (43%), Positives = 81/139 (58%), Gaps = 2/139 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y
Sbjct: 138 HRDLKAENLLLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYE 192
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--I 179
D+WSMGVVLY +V G LPFD +L+Q + F +S +C LI R +
Sbjct: 193 GPQLDIWSMGVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLV 251
Query: 178 LAPLKMRVKIPQILADPWL 122
L P K R+ I QI W+
Sbjct: 252 LDPSK-RLTIAQIKEHKWM 269
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/70 (37%), Positives = 42/70 (60%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y + T+G G++A VK+ +VAIKII K Q L+K + RE++++K L H +
Sbjct: 18 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEK-IYREVQIMKMLDHPH 76
Query: 565 LIRFLQAIET 536
+I+ Q +ET
Sbjct: 77 IIKLYQVMET 86
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 101 bits (241), Expect = 4e-21
Identities = 60/139 (43%), Positives = 81/139 (58%), Gaps = 2/139 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D+ +NIK++DFGF K+G L T+CGS YA+PE+ +G Y
Sbjct: 164 HRDLKAENLLLDNNMNIKIADFGFGNFF---KSG--ELLATWCGSPPYAAPEVFEGQQYE 218
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITR--I 179
D+WSMGVVLY +V G LPFD +L+Q + F +S +C LI R +
Sbjct: 219 GPQLDIWSMGVVLYVLVCGALPFDGPT-LPILRQRVLEGRFRIPYFMSEDCEHLIRRMLV 277
Query: 178 LAPLKMRVKIPQILADPWL 122
L P K R+ I QI W+
Sbjct: 278 LDPSK-RLTIAQIKEHKWM 295
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/70 (37%), Positives = 42/70 (60%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y + T+G G++A VK+ +VAIKII K Q L+K + RE++++K L H +
Sbjct: 44 YDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEK-IYREVQIMKMLDHPH 102
Query: 565 LIRFLQAIET 536
+I+ Q +ET
Sbjct: 103 IIKLYQVMET 112
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 99.5 bits (237), Expect = 1e-20
Identities = 60/140 (42%), Positives = 84/140 (60%), Gaps = 3/140 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D ++IKL+DFGF + K+G LS T+CGS YA+PE+ +G Y
Sbjct: 147 HRDLKTENLLLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYE 201
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D+WS+GVVLY +V G LPFD N L ++V + + P +S +C LI R+L
Sbjct: 202 GPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIRRML 259
Query: 175 A--PLKMRVKIPQILADPWL 122
P + R+ I QI W+
Sbjct: 260 VVDPAR-RITIAQIRQHRWM 278
Score = 54.0 bits (124), Expect = 7e-07
Identities = 33/100 (33%), Positives = 59/100 (59%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y + RT+G G++A VK+A QVAIKII K + L+K + RE++++K L H +
Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEK-IYREVQLMKLLNHPH 85
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHM 446
+I+ Q +ET +D+ ++ + N ++ D+ + GH+
Sbjct: 86 IIKLYQVMET--KDML--YIVTEFAKNGEMFDYLTSNGHL 121
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 99.5 bits (237), Expect = 1e-20
Identities = 60/140 (42%), Positives = 84/140 (60%), Gaps = 3/140 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D ++IKL+DFGF + K+G LS T+CGS YA+PE+ +G Y
Sbjct: 128 HRDLKTENLLLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYE 182
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D+WS+GVVLY +V G LPFD N L ++V + + P +S +C LI R+L
Sbjct: 183 GPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIRRML 240
Query: 175 A--PLKMRVKIPQILADPWL 122
P + R+ I QI W+
Sbjct: 241 VVDPAR-RITIAQIRQHRWM 259
Score = 54.0 bits (124), Expect = 7e-07
Identities = 33/100 (33%), Positives = 59/100 (59%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y + RT+G G++A VK+A QVAIKII K + L+K + RE++++K L H +
Sbjct: 8 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEK-IYREVQLMKLLNHPH 66
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHM 446
+I+ Q +ET +D+ ++ + N ++ D+ + GH+
Sbjct: 67 IIKLYQVMET--KDML--YIVTEFAKNGEMFDYLTSNGHL 102
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 99.5 bits (237), Expect = 1e-20
Identities = 60/140 (42%), Positives = 84/140 (60%), Gaps = 3/140 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL+D ++IKL+DFGF + K+G LS T+CGS YA+PE+ +G Y
Sbjct: 147 HRDLKTENLLLDGNMDIKLADFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGKEYE 201
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
D+WS+GVVLY +V G LPFD N L ++V + + P +S +C LI R+L
Sbjct: 202 GPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIRRML 259
Query: 175 A--PLKMRVKIPQILADPWL 122
P + R+ I QI W+
Sbjct: 260 VVDPAR-RITIAQIRQHRWM 278
Score = 54.0 bits (124), Expect = 7e-07
Identities = 33/100 (33%), Positives = 59/100 (59%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y + RT+G G++A VK+A QVAIKII K + L+K + RE++++K L H +
Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEK-IYREVQLMKLLNHPH 85
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHM 446
+I+ Q +ET +D+ ++ + N ++ D+ + GH+
Sbjct: 86 IIKLYQVMET--KDML--YIVTEFAKNGEMFDYLTSNGHL 121
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 99.1 bits (236), Expect = 2e-20
Identities = 55/139 (39%), Positives = 80/139 (57%), Gaps = 2/139 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL D +KL DFG KPK +T CGS AYA+PE+++G Y
Sbjct: 135 HRDLKPENLLFDEYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYL 191
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
++DVWSMG++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L
Sbjct: 192 GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQML 249
Query: 175 -APLKMRVKIPQILADPWL 122
K R+ + +L PW+
Sbjct: 250 QVDPKKRISMKNLLNHPWI 268
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/73 (34%), Positives = 40/73 (54%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L TIG+G +A VK+A VAIKI+ K D + + EIE +K L+H++
Sbjct: 16 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQH 73
Query: 565 LIRFLQAIETTHR 527
+ + +ET ++
Sbjct: 74 ICQLYHVLETANK 86
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 99.1 bits (236), Expect = 2e-20
Identities = 55/139 (39%), Positives = 80/139 (57%), Gaps = 2/139 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL D +KL DFG KPK +T CGS AYA+PE+++G Y
Sbjct: 130 HRDLKPENLLFDEYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYL 186
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
++DVWSMG++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L
Sbjct: 187 GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQML 244
Query: 175 -APLKMRVKIPQILADPWL 122
K R+ + +L PW+
Sbjct: 245 QVDPKKRISMKNLLNHPWI 263
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/73 (34%), Positives = 40/73 (54%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L TIG+G +A VK+A VAIKI+ K D + + EIE +K L+H++
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQH 68
Query: 565 LIRFLQAIETTHR 527
+ + +ET ++
Sbjct: 69 ICQLYHVLETANK 81
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 99.1 bits (236), Expect = 2e-20
Identities = 55/139 (39%), Positives = 80/139 (57%), Gaps = 2/139 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL D +KL DFG KPK +T CGS AYA+PE+++G Y
Sbjct: 130 HRDLKPENLLFDEYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYL 186
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
++DVWSMG++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L
Sbjct: 187 GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQML 244
Query: 175 -APLKMRVKIPQILADPWL 122
K R+ + +L PW+
Sbjct: 245 QVDPKKRISMKNLLNHPWI 263
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/73 (34%), Positives = 40/73 (54%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L TIG+G +A VK+A VAIKI+ K D + + EIE +K L+H++
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQH 68
Query: 565 LIRFLQAIETTHR 527
+ + +ET ++
Sbjct: 69 ICQLYHVLETANK 81
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 99.1 bits (236), Expect = 2e-20
Identities = 55/139 (39%), Positives = 80/139 (57%), Gaps = 2/139 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL D +KL DFG KPK +T CGS AYA+PE+++G Y
Sbjct: 130 HRDLKPENLLFDEYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYL 186
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
++DVWSMG++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L
Sbjct: 187 GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQML 244
Query: 175 -APLKMRVKIPQILADPWL 122
K R+ + +L PW+
Sbjct: 245 QVDPKKRISMKNLLNHPWI 263
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/73 (34%), Positives = 40/73 (54%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L TIG+G +A VK+A VAIKI+ K D + + EIE +K L+H++
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQH 68
Query: 565 LIRFLQAIETTHR 527
+ + +ET ++
Sbjct: 69 ICQLYHVLETANK 81
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 99.1 bits (236), Expect = 2e-20
Identities = 55/139 (39%), Positives = 80/139 (57%), Gaps = 2/139 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL D +KL DFG KPK +T CGS AYA+PE+++G Y
Sbjct: 130 HRDLKPENLLFDEYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYL 186
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
++DVWSMG++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L
Sbjct: 187 GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQML 244
Query: 175 -APLKMRVKIPQILADPWL 122
K R+ + +L PW+
Sbjct: 245 QVDPKKRISMKNLLNHPWI 263
Score = 44.4 bits (100), Expect = 5e-04
Identities = 25/73 (34%), Positives = 40/73 (54%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L TIG+G +A VK+A VAIKI+ K D + + EIE +K L+H++
Sbjct: 11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPR--IKTEIEALKNLRHQH 68
Query: 565 LIRFLQAIETTHR 527
+ + +ET ++
Sbjct: 69 ICQLYHVLETANK 81
>AB183428-1|BAF73616.1| 580|Homo sapiens maternal embryonic luecine
zipper kinase v3 protein.
Length = 580
Score = 99.1 bits (236), Expect = 2e-20
Identities = 55/139 (39%), Positives = 80/139 (57%), Gaps = 2/139 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL D +KL DFG KPK +T CGS AYA+PE+++G Y
Sbjct: 59 HRDLKPENLLFDEYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYL 115
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
++DVWSMG++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L
Sbjct: 116 GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQML 173
Query: 175 -APLKMRVKIPQILADPWL 122
K R+ + +L PW+
Sbjct: 174 QVDPKKRISMKNLLNHPWI 192
>AB183427-1|BAF73615.1| 619|Homo sapiens maternal embryonic leucine
zipper kinase v2 protein.
Length = 619
Score = 99.1 bits (236), Expect = 2e-20
Identities = 55/139 (39%), Positives = 80/139 (57%), Gaps = 2/139 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K ENLL D +KL DFG KPK +T CGS AYA+PE+++G Y
Sbjct: 98 HRDLKPENLLFDEYHKLKLIDFGLCA---KPKGNKDYHLQTCCGSLAYAAPELIQGKSYL 154
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
++DVWSMG++LY ++ G LPFDD N L K++ + K P+ +S L+ ++L
Sbjct: 155 GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPK--WLSPSSILLLQQML 212
Query: 175 -APLKMRVKIPQILADPWL 122
K R+ + +L PW+
Sbjct: 213 QVDPKKRISMKNLLNHPWI 231
>BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein.
Length = 1102
Score = 97.5 bits (232), Expect = 6e-20
Identities = 59/150 (39%), Positives = 81/150 (54%), Gaps = 3/150 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ F HRD+K ENLL+D LNIK++DFGF+ + L +T+CGS YA+
Sbjct: 17 VYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ-----LLKTWCGSPPYAA 71
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSA 206
PE+ +G Y D+WS+GVVLY +V G LPFD + L +V K P +S
Sbjct: 72 PELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPF--FMST 129
Query: 205 ECRKLITR--ILAPLKMRVKIPQILADPWL 122
EC LI +L P K R+ + QI W+
Sbjct: 130 ECEHLIRHMLVLDPNK-RLSMEQICKHKWM 158
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 97.5 bits (232), Expect = 6e-20
Identities = 59/150 (39%), Positives = 81/150 (54%), Gaps = 3/150 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ F HRD+K ENLL+D LNIK++DFGF+ + L +T+CGS YA+
Sbjct: 118 VYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ-----LLKTWCGSPPYAA 172
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSA 206
PE+ +G Y D+WS+GVVLY +V G LPFD + L +V K P +S
Sbjct: 173 PELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPF--FMST 230
Query: 205 ECRKLITR--ILAPLKMRVKIPQILADPWL 122
EC LI +L P K R+ + QI W+
Sbjct: 231 ECEHLIRHMLVLDPNK-RLSMEQICKHKWM 259
Score = 56.4 bits (130), Expect = 1e-07
Identities = 31/70 (44%), Positives = 44/70 (62%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y + RTIG G++A VK A+ +VAIKII K Q + LKK RE++++K L H +
Sbjct: 8 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPH 66
Query: 565 LIRFLQAIET 536
+IR Q +ET
Sbjct: 67 IIRLYQVMET 76
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 97.5 bits (232), Expect = 6e-20
Identities = 51/123 (41%), Positives = 75/123 (60%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 131 FCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 185
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 186 VIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 244
Query: 196 KLI 188
L+
Sbjct: 245 SLL 247
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 97.5 bits (232), Expect = 6e-20
Identities = 51/123 (41%), Positives = 75/123 (60%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 131 FCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 185
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 186 VIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 244
Query: 196 KLI 188
L+
Sbjct: 245 SLL 247
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 97.5 bits (232), Expect = 6e-20
Identities = 51/123 (41%), Positives = 75/123 (60%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 177 FCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 231
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 232 VIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 290
Query: 196 KLI 188
L+
Sbjct: 291 SLL 293
>AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 603
Score = 97.5 bits (232), Expect = 6e-20
Identities = 51/123 (41%), Positives = 75/123 (60%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 60 FCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 114
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 115 VIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 173
Query: 196 KLI 188
L+
Sbjct: 174 SLL 176
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 97.5 bits (232), Expect = 6e-20
Identities = 51/123 (41%), Positives = 75/123 (60%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 131 FCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 185
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 186 VIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 244
Query: 196 KLI 188
L+
Sbjct: 245 SLL 247
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 97.5 bits (232), Expect = 6e-20
Identities = 51/123 (41%), Positives = 75/123 (60%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 131 FCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 185
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 186 VIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 244
Query: 196 KLI 188
L+
Sbjct: 245 SLL 247
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 97.5 bits (232), Expect = 6e-20
Identities = 51/123 (41%), Positives = 75/123 (60%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 131 FCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 185
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 186 VIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 244
Query: 196 KLI 188
L+
Sbjct: 245 SLL 247
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 97.5 bits (232), Expect = 6e-20
Identities = 51/123 (41%), Positives = 75/123 (60%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 131 FCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 185
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 186 VIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 244
Query: 196 KLI 188
L+
Sbjct: 245 SLL 247
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 97.5 bits (232), Expect = 6e-20
Identities = 51/123 (41%), Positives = 75/123 (60%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
F + HRD+K ENLL+D NI+++DFG A + +L ET CGS YA PE
Sbjct: 131 FCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGD-----SLLETSCGSPHYACPE 185
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+++G Y + +DVWS GV+L+A++ G LPFDD N QLL++V+ V F + +C+
Sbjct: 186 VIRGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGV-FHMPHFIPPDCQ 244
Query: 196 KLI 188
L+
Sbjct: 245 SLL 247
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 97.5 bits (232), Expect = 6e-20
Identities = 59/150 (39%), Positives = 81/150 (54%), Gaps = 3/150 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ F HRD+K ENLL+D LNIK++DFGF+ + L +T+CGS YA+
Sbjct: 226 VYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQ-----LLKTWCGSPPYAA 280
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSA 206
PE+ +G Y D+WS+GVVLY +V G LPFD + L +V K P +S
Sbjct: 281 PELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPF--FMST 338
Query: 205 ECRKLITR--ILAPLKMRVKIPQILADPWL 122
EC LI +L P K R+ + QI W+
Sbjct: 339 ECEHLIRHMLVLDPNK-RLSMEQICKHKWM 367
Score = 56.4 bits (130), Expect = 1e-07
Identities = 31/70 (44%), Positives = 44/70 (62%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y + RTIG G++A VK A+ +VAIKII K Q + LKK RE++++K L H +
Sbjct: 116 YEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIF-REVQIMKMLCHPH 174
Query: 565 LIRFLQAIET 536
+IR Q +ET
Sbjct: 175 IIRLYQVMET 184
>D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein.
Length = 766
Score = 97.1 bits (231), Expect = 7e-20
Identities = 64/181 (35%), Positives = 98/181 (54%), Gaps = 7/181 (3%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
I + + HRD+K EN++ GL +KL+DFGF+ K T CGS AY
Sbjct: 128 ISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAY 181
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKV 212
++PEIL G Y D+WS+GV+L+ +V G+ PF + N ++ L + + K + P V
Sbjct: 182 SAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH--V 239
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL---NPNQQSKHDETDLQEHAKTSKEEIKS 44
S EC+ LITR+L K R + +I PWL +P+ +K++ L + S+EE S
Sbjct: 240 SKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSEEEHNS 298
Query: 43 V 41
+
Sbjct: 299 I 299
Score = 39.5 bits (88), Expect = 0.015
Identities = 22/70 (31%), Positives = 39/70 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +T+G G +A VK+A +VA+K+I K + L +E+ +K ++H N
Sbjct: 17 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL-DTLATGHLFQEVRCMKLVQHPN 75
Query: 565 LIRFLQAIET 536
++R + I+T
Sbjct: 76 IVRLYEVIDT 85
>AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein.
Length = 765
Score = 97.1 bits (231), Expect = 7e-20
Identities = 64/181 (35%), Positives = 98/181 (54%), Gaps = 7/181 (3%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
I + + HRD+K EN++ GL +KL+DFGF+ K T CGS AY
Sbjct: 127 ISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAY 180
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKV 212
++PEIL G Y D+WS+GV+L+ +V G+ PF + N ++ L + + K + P V
Sbjct: 181 SAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH--V 238
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL---NPNQQSKHDETDLQEHAKTSKEEIKS 44
S EC+ LITR+L K R + +I PWL +P+ +K++ L + S+EE S
Sbjct: 239 SKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSEEEHNS 297
Query: 43 V 41
+
Sbjct: 298 I 298
Score = 39.5 bits (88), Expect = 0.015
Identities = 22/70 (31%), Positives = 39/70 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +T+G G +A VK+A +VA+K+I K + L +E+ +K ++H N
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL-DTLATGHLFQEVRCMKLVQHPN 74
Query: 565 LIRFLQAIET 536
++R + I+T
Sbjct: 75 IVRLYEVIDT 84
>BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein.
Length = 765
Score = 96.3 bits (229), Expect = 1e-19
Identities = 64/181 (35%), Positives = 98/181 (54%), Gaps = 7/181 (3%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
I + + HRD+K EN++ GL +KL+DFGF+ K T CGS AY
Sbjct: 127 ISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAY 180
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKV 212
++PEIL G Y D+WS+GV+L+ +V G+ PF + N ++ L + + K + P V
Sbjct: 181 SAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSH--V 238
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL---NPNQQSKHDETDLQEHAKTSKEEIKS 44
S EC+ LITR+L K R + +I PWL +P+ +K++ L + S+EE S
Sbjct: 239 SKECKDLITRMLQRDPKRRAYLEEIENHPWLQGVDPSPATKYN-IPLVSYKNLSEEEHNS 297
Query: 43 V 41
+
Sbjct: 298 I 298
Score = 39.5 bits (88), Expect = 0.015
Identities = 22/70 (31%), Positives = 39/70 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +T+G G +A VK+A +VA+K+I K + L +E+ +K ++H N
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL-DTLATGHLFQEVRCMKLVQHPN 74
Query: 565 LIRFLQAIET 536
++R + I+T
Sbjct: 75 IVRLYEVIDT 84
>AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein.
Length = 786
Score = 93.5 bits (222), Expect = 9e-19
Identities = 60/143 (41%), Positives = 84/143 (58%), Gaps = 6/143 (4%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLS---DFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGV 362
HRD+K ENLL+D ++IKL+ DFGF + K+G LS T+CGS YA+PE+ +G
Sbjct: 147 HRDLKTENLLLDGNMDIKLAGTEDFGFGNFY---KSGE-PLS-TWCGSPPYAAPEVFEGK 201
Query: 361 PYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLIT 185
Y D+WS+GVVLY +V G LPFD N L ++V + + P +S +C LI
Sbjct: 202 EYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPF--FMSQDCESLIR 259
Query: 184 RILA--PLKMRVKIPQILADPWL 122
R+L P + R+ I QI W+
Sbjct: 260 RMLVVDPAR-RITIAQIRQHRWM 281
Score = 54.0 bits (124), Expect = 7e-07
Identities = 33/100 (33%), Positives = 59/100 (59%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y + RT+G G++A VK+A QVAIKII K + L+K + RE++++K L H +
Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEK-IYREVQLMKLLNHPH 85
Query: 565 LIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHM 446
+I+ Q +ET +D+ ++ + N ++ D+ + GH+
Sbjct: 86 IIKLYQVMET--KDML--YIVTEFAKNGEMFDYLTSNGHL 121
>BC062616-1|AAH62616.1| 424|Homo sapiens protein serine kinase H1
protein.
Length = 424
Score = 92.7 bits (220), Expect = 2e-18
Identities = 58/154 (37%), Positives = 86/154 (55%), Gaps = 7/154 (4%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDH-GLNIKL--SDFGFARGHMKPKNGVFALSETFCGSYA 392
+R+L A+ THRD+K ENLL H G + K+ +DFG A K G L +T CG+
Sbjct: 206 VRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR---KKGDDCLMKTTCGTPE 262
Query: 391 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPRE-- 221
Y +PE+L PY D+W++GV+ Y ++ G +PF+D N T+L +Q+ + K S+ E
Sbjct: 263 YIAPEVLVRKPYT-NSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPW 321
Query: 220 PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 122
P VS + I R+L R+ Q L PW+
Sbjct: 322 PSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
>AJ272212-1|CAB91984.1| 424|Homo sapiens protein serine kinase
protein.
Length = 424
Score = 92.7 bits (220), Expect = 2e-18
Identities = 58/154 (37%), Positives = 86/154 (55%), Gaps = 7/154 (4%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDH-GLNIKL--SDFGFARGHMKPKNGVFALSETFCGSYA 392
+R+L A+ THRD+K ENLL H G + K+ +DFG A K G L +T CG+
Sbjct: 206 VRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR---KKGDDCLMKTTCGTPE 262
Query: 391 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPRE-- 221
Y +PE+L PY D+W++GV+ Y ++ G +PF+D N T+L +Q+ + K S+ E
Sbjct: 263 YIAPEVLVRKPYT-NSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPW 321
Query: 220 PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 122
P VS + I R+L R+ Q L PW+
Sbjct: 322 PSVSNLAKDFIDRLLTVDPGARMTALQALRHPWV 355
>BC043487-1|AAH43487.1| 505|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 1,
alpha protein.
Length = 505
Score = 91.1 bits (216), Expect = 5e-18
Identities = 55/178 (30%), Positives = 95/178 (53%), Gaps = 5/178 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ +L + HRDIK NLL+ ++K++DFG + G A + G+ A+ +
Sbjct: 263 LEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF----EGNDAQLSSTAGTPAFMA 318
Query: 382 PEILK--GVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE + G + + DVW+ GV LY VYG+ PF D L ++++N+ V FP EP++
Sbjct: 319 PEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEI 378
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWLNPN-QQSKHDETDLQEHAKTSKEEIKS 44
S E + LI ++L + R+ +P I PW+ N ++ E + + ++EE+K+
Sbjct: 379 SEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKN 436
>AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein
protein.
Length = 505
Score = 91.1 bits (216), Expect = 5e-18
Identities = 55/178 (30%), Positives = 95/178 (53%), Gaps = 5/178 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ +L + HRDIK NLL+ ++K++DFG + G A + G+ A+ +
Sbjct: 263 LEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF----EGNDAQLSSTAGTPAFMA 318
Query: 382 PEILK--GVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE + G + + DVW+ GV LY VYG+ PF D L ++++N+ V FP EP++
Sbjct: 319 PEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEI 378
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWLNPN-QQSKHDETDLQEHAKTSKEEIKS 44
S E + LI ++L + R+ +P I PW+ N ++ E + + ++EE+K+
Sbjct: 379 SEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKN 436
>AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein
protein.
Length = 505
Score = 91.1 bits (216), Expect = 5e-18
Identities = 55/178 (30%), Positives = 95/178 (53%), Gaps = 5/178 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ +L + HRDIK NLL+ ++K++DFG + G A + G+ A+ +
Sbjct: 263 LEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF----EGNDAQLSSTAGTPAFMA 318
Query: 382 PEILK--GVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE + G + + DVW+ GV LY VYG+ PF D L ++++N+ V FP EP++
Sbjct: 319 PEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPEI 378
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWLNPN-QQSKHDETDLQEHAKTSKEEIKS 44
S E + LI ++L + R+ +P I PW+ N ++ E + + ++EE+K+
Sbjct: 379 SEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKN 436
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 89.8 bits (213), Expect = 1e-17
Identities = 59/160 (36%), Positives = 84/160 (52%), Gaps = 6/160 (3%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETF---CGSYA 392
+ L HRD+K ENLL+D NIKL DFG + G+ S+ F CGS A
Sbjct: 174 VEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSN-----CAGILGYSDPFSTQCGSPA 228
Query: 391 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPF--DDTNYTQLLKQVQNKVSFPREP 218
YA+PE+L Y P+ DVWS+GV +YA++ G LPF + + L +++ +K P
Sbjct: 229 YAAPELLARKKYGPK-IDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPT 287
Query: 217 KVSAECRKLITRILAPLKM-RVKIPQILADPWLNPNQQSK 101
++S + +L P + R I Q LA+ WLN N K
Sbjct: 288 QLSTGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTGK 327
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/72 (36%), Positives = 43/72 (59%), Gaps = 2/72 (2%)
Frame = -1
Query: 745 YMLG-RTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGD-YLKKFLPREIEVVKGLKH 572
Y++G R +G GS+A V+ +VAIK+I K +A D Y+ K L RE ++ + ++H
Sbjct: 61 YLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRH 120
Query: 571 ENLIRFLQAIET 536
N+ + L +ET
Sbjct: 121 PNITQLLDILET 132
>M14504-1|AAA36519.1| 150|Homo sapiens protein ( Human
protein-serine kinase mRNA, clone PSK-H1. ).
Length = 150
Score = 89.4 bits (212), Expect = 1e-17
Identities = 53/135 (39%), Positives = 79/135 (58%), Gaps = 6/135 (4%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDH-GLNIKL--SDFGFARGHMKPKNGVFALSETFCGSYA 392
+R+L A+ THRD+K ENLL H G + K+ +DFG A K G L +T CG+
Sbjct: 8 VRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASAR---KKGDDCLMKTTCGTPE 64
Query: 391 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPRE-- 221
Y +PE+L PY D+W++GV+ Y ++ G +PF+D N T+L +Q+ + K S+ E
Sbjct: 65 YIAPEVLVRKPYT-NSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPW 123
Query: 220 PKVSAECRKLITRIL 176
P VS + I R+L
Sbjct: 124 PSVSNLAKDFIDRLL 138
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 88.2 bits (209), Expect = 3e-17
Identities = 53/145 (36%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K EN+L+D +N K++DFG + +G F T CGS YA+PE++ G Y
Sbjct: 137 HRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYA 191
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA 173
+ D+WS GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L
Sbjct: 192 GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQ 250
Query: 172 --PLKMRVKIPQILADPWLNPNQQS 104
PLK R I I W + S
Sbjct: 251 VDPLK-RATIKDIREHEWFKQDLPS 274
Score = 40.3 bits (90), Expect = 0.009
Identities = 20/70 (28%), Positives = 39/70 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y+LG T+G G++ V + +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVNIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 565 LIRFLQAIET 536
+I+ Q I T
Sbjct: 76 IIKLYQVIST 85
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 88.2 bits (209), Expect = 3e-17
Identities = 53/145 (36%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K EN+L+D +N K++DFG + +G F T CGS YA+PE++ G Y
Sbjct: 137 HRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYA 191
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA 173
+ D+WS GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L
Sbjct: 192 GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQ 250
Query: 172 --PLKMRVKIPQILADPWLNPNQQS 104
PLK R I I W + S
Sbjct: 251 VDPLK-RATIKDIREHEWFKQDLPS 274
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/70 (30%), Positives = 40/70 (57%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y+LG T+G G++ VK+ +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 565 LIRFLQAIET 536
+I+ Q I T
Sbjct: 76 IIKLYQVIST 85
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 88.2 bits (209), Expect = 3e-17
Identities = 53/145 (36%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K EN+L+D +N K++DFG + +G F T CGS YA+PE++ G Y
Sbjct: 137 HRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYA 191
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA 173
+ D+WS GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L
Sbjct: 192 GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQ 250
Query: 172 --PLKMRVKIPQILADPWLNPNQQS 104
PLK R I I W + S
Sbjct: 251 VDPLK-RATIKDIREHEWFKQDLPS 274
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/70 (30%), Positives = 40/70 (57%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y+LG T+G G++ VK+ +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 565 LIRFLQAIET 536
+I+ Q I T
Sbjct: 76 IIKLYQVIST 85
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 88.2 bits (209), Expect = 3e-17
Identities = 53/145 (36%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K EN+L+D +N K++DFG + +G F T CGS YA+PE++ G Y
Sbjct: 137 HRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYA 191
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA 173
+ D+WS GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L
Sbjct: 192 GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQ 250
Query: 172 --PLKMRVKIPQILADPWLNPNQQS 104
PLK R I I W + S
Sbjct: 251 VDPLK-RATIKDIREHEWFKQDLPS 274
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/70 (30%), Positives = 40/70 (57%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y+LG T+G G++ VK+ +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 565 LIRFLQAIET 536
+I+ Q I T
Sbjct: 76 IIKLYQVIST 85
>BC031647-1|AAH31647.1| 520|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 1,
alpha protein.
Length = 520
Score = 88.2 bits (209), Expect = 3e-17
Identities = 54/178 (30%), Positives = 94/178 (52%), Gaps = 5/178 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ +L + HRDIK NLL+ ++K++DFG + G A + G+ A+ +
Sbjct: 301 LEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF----EGNDAQLSSTAGTPAFMA 356
Query: 382 PEILK--GVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE + G + + DVW+ GV LY VYG+ PF D L ++++N+ V FP P++
Sbjct: 357 PEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEGPEI 416
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWLNPN-QQSKHDETDLQEHAKTSKEEIKS 44
S E + LI ++L + R+ +P I PW+ N ++ E + + ++EE+K+
Sbjct: 417 SEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSEEEHCSVVEVTEEEVKN 474
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 88.2 bits (209), Expect = 3e-17
Identities = 53/145 (36%), Positives = 79/145 (54%), Gaps = 2/145 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K EN+L+D +N K++DFG + +G F T CGS YA+PE++ G Y
Sbjct: 137 HRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYA 191
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA 173
+ D+WS GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L
Sbjct: 192 GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQ 250
Query: 172 --PLKMRVKIPQILADPWLNPNQQS 104
PLK R I I W + S
Sbjct: 251 VDPLK-RATIKDIREHEWFKQDLPS 274
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/70 (30%), Positives = 40/70 (57%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y+LG T+G G++ VK+ +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 565 LIRFLQAIET 536
+I+ Q I T
Sbjct: 76 IIKLYQVIST 85
>BC126182-1|AAI26183.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 87.4 bits (207), Expect = 6e-17
Identities = 54/154 (35%), Positives = 89/154 (57%), Gaps = 7/154 (4%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHG---LNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 392
IR+L A++ THR++K ENLL H I ++DFG A + K+G + + +T CG+
Sbjct: 171 IRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA--YSGKKSGDWTM-KTLCGTPE 227
Query: 391 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPRE-- 221
Y +PE+L PY D+W++GV+ YA++ G LPFDD + T+L +++ + K ++ E
Sbjct: 228 YIAPEVLLRKPYTSA-VDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPW 286
Query: 220 PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 122
P +S + I ++L R+ Q L PW+
Sbjct: 287 PSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV 320
>BC126180-1|AAI26181.1| 385|Homo sapiens protein serine kinase H2
protein.
Length = 385
Score = 87.4 bits (207), Expect = 6e-17
Identities = 54/154 (35%), Positives = 89/154 (57%), Gaps = 7/154 (4%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHG---LNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 392
IR+L A++ THR++K ENLL H I ++DFG A + K+G + + +T CG+
Sbjct: 171 IRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA--YSGKKSGDWTM-KTLCGTPE 227
Query: 391 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPRE-- 221
Y +PE+L PY D+W++GV+ YA++ G LPFDD + T+L +++ + K ++ E
Sbjct: 228 YIAPEVLLRKPYTSA-VDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPW 286
Query: 220 PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 122
P +S + I ++L R+ Q L PW+
Sbjct: 287 PSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV 320
>AY037806-1|AAK59985.1| 385|Homo sapiens serine/threonine kinase
PSKH2 protein.
Length = 385
Score = 87.4 bits (207), Expect = 6e-17
Identities = 54/154 (35%), Positives = 89/154 (57%), Gaps = 7/154 (4%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHG---LNIKLSDFGFARGHMKPKNGVFALSETFCGSYA 392
IR+L A++ THR++K ENLL H I ++DFG A + K+G + + +T CG+
Sbjct: 171 IRYLHALQITHRNLKPENLLYYHPGEESKILITDFGLA--YSGKKSGDWTM-KTLCGTPE 227
Query: 391 YASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPRE-- 221
Y +PE+L PY D+W++GV+ YA++ G LPFDD + T+L +++ + K ++ E
Sbjct: 228 YIAPEVLLRKPYTSA-VDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPW 286
Query: 220 PKVSAECRKLITRIL-APLKMRVKIPQILADPWL 122
P +S + I ++L R+ Q L PW+
Sbjct: 287 PSISHLAKDFIDKLLILEAGHRMSAGQALDHPWV 320
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 86.2 bits (204), Expect = 1e-16
Identities = 51/138 (36%), Positives = 76/138 (55%), Gaps = 2/138 (1%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K EN+L+D +N K++DFG + +G F T CGS Y +PE++ G Y
Sbjct: 137 HRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYTAPEVISGRLYA 191
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA 173
+ D+WS GV+LYA++ G LPFDD + L K+++ V + E ++ L+ +L
Sbjct: 192 GPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPE-YLNRSVATLLMHMLQ 250
Query: 172 --PLKMRVKIPQILADPW 125
PLK R I I W
Sbjct: 251 VDPLK-RATIKDIREHEW 267
Score = 42.3 bits (95), Expect = 0.002
Identities = 21/70 (30%), Positives = 40/70 (57%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y+LG T+G G++ VK+ +VA+KI+++ + + + REI+ +K +H +
Sbjct: 16 YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQNLKLFRHPH 75
Query: 565 LIRFLQAIET 536
+I+ Q I T
Sbjct: 76 IIKLYQVIST 85
>D50925-1|BAA09484.2| 1351|Homo sapiens KIAA0135 protein.
Length = 1351
Score = 86.2 bits (204), Expect = 1e-16
Identities = 50/148 (33%), Positives = 83/148 (56%), Gaps = 1/148 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ +L+ + HRDIK EN+++ IKL DFG A + K L TFCG+ Y +
Sbjct: 1144 VGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTIEYCA 1198
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAE 203
PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P VS E
Sbjct: 1199 PEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--LVSKE 1251
Query: 202 CRKLITRILAPL-KMRVKIPQILADPWL 122
L++ +L P+ + R + +++ DPW+
Sbjct: 1252 LMSLVSGLLQPVPERRTTLEKLVTDPWV 1279
>BC063585-1|AAH63585.1| 1323|Homo sapiens PAS domain containing
serine/threonine kinase protein.
Length = 1323
Score = 86.2 bits (204), Expect = 1e-16
Identities = 50/148 (33%), Positives = 83/148 (56%), Gaps = 1/148 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ +L+ + HRDIK EN+++ IKL DFG A + K L TFCG+ Y +
Sbjct: 1116 VGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTIEYCA 1170
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAE 203
PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P VS E
Sbjct: 1171 PEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--LVSKE 1223
Query: 202 CRKLITRILAPL-KMRVKIPQILADPWL 122
L++ +L P+ + R + +++ DPW+
Sbjct: 1224 LMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
>BC043495-1|AAH43495.1| 953|Homo sapiens PASK protein protein.
Length = 953
Score = 86.2 bits (204), Expect = 1e-16
Identities = 50/148 (33%), Positives = 83/148 (56%), Gaps = 1/148 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ +L+ + HRDIK EN+++ IKL DFG A + K L TFCG+ Y +
Sbjct: 746 VGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTIEYCA 800
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAE 203
PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P VS E
Sbjct: 801 PEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--LVSKE 853
Query: 202 CRKLITRILAPL-KMRVKIPQILADPWL 122
L++ +L P+ + R + +++ DPW+
Sbjct: 854 LMSLVSGLLQPVPERRTTLEKLVTDPWV 881
>BC017575-1|AAH17575.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 86.2 bits (204), Expect = 1e-16
Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 3/149 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L I THRDIK ENLL+D N+K+SDFG A + N L CG+ Y +PE
Sbjct: 120 YLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPE 177
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAE 203
+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++ K+ +
Sbjct: 178 LLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSA 237
Query: 202 CRKLITRILAP-LKMRVKIPQILADPWLN 119
L+ +IL R+ IP I D W N
Sbjct: 238 PLALLHKILVENPSARITIPDIKKDRWYN 266
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/62 (32%), Positives = 36/62 (58%)
Frame = -1
Query: 739 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 560
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 559 RF 554
+F
Sbjct: 69 KF 70
>BC004202-1|AAH04202.1| 476|Homo sapiens CHEK1 protein protein.
Length = 476
Score = 86.2 bits (204), Expect = 1e-16
Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 3/149 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L I THRDIK ENLL+D N+K+SDFG A + N L CG+ Y +PE
Sbjct: 120 YLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPE 177
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAE 203
+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++ K+ +
Sbjct: 178 LLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSA 237
Query: 202 CRKLITRILAP-LKMRVKIPQILADPWLN 119
L+ +IL R+ IP I D W N
Sbjct: 238 PLALLHKILVENPSARITIPDIKKDRWYN 266
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/62 (32%), Positives = 36/62 (58%)
Frame = -1
Query: 739 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 560
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 559 RF 554
+F
Sbjct: 69 KF 70
>AF527555-1|AAM78553.1| 476|Homo sapiens CHK1 checkpoint homolog
(S. pombe) protein.
Length = 476
Score = 86.2 bits (204), Expect = 1e-16
Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 3/149 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L I THRDIK ENLL+D N+K+SDFG A + N L CG+ Y +PE
Sbjct: 120 YLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPE 177
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAE 203
+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++ K+ +
Sbjct: 178 LLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSA 237
Query: 202 CRKLITRILAP-LKMRVKIPQILADPWLN 119
L+ +IL R+ IP I D W N
Sbjct: 238 PLALLHKILVENPSARITIPDIKKDRWYN 266
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/62 (32%), Positives = 36/62 (58%)
Frame = -1
Query: 739 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 560
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 559 RF 554
+F
Sbjct: 69 KF 70
>AF387103-1|AAK69752.1| 1323|Homo sapiens PAS-kinase protein.
Length = 1323
Score = 86.2 bits (204), Expect = 1e-16
Identities = 50/148 (33%), Positives = 83/148 (56%), Gaps = 1/148 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ +L+ + HRDIK EN+++ IKL DFG A + K L TFCG+ Y +
Sbjct: 1116 VGYLRLKDIIHRDIKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTIEYCA 1170
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAE 203
PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P VS E
Sbjct: 1171 PEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--LVSKE 1223
Query: 202 CRKLITRILAPL-KMRVKIPQILADPWL 122
L++ +L P+ + R + +++ DPW+
Sbjct: 1224 LMSLVSGLLQPVPERRTTLEKLVTDPWV 1251
>AF032874-1|AAB88852.1| 476|Homo sapiens protein kinase protein.
Length = 476
Score = 86.2 bits (204), Expect = 1e-16
Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 3/149 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L I THRDIK ENLL+D N+K+SDFG A + N L CG+ Y +PE
Sbjct: 120 YLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPE 177
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAE 203
+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++ K+ +
Sbjct: 178 LLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSA 237
Query: 202 CRKLITRILAP-LKMRVKIPQILADPWLN 119
L+ +IL R+ IP I D W N
Sbjct: 238 PLALLHKILVENPSARITIPDIKKDRWYN 266
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/62 (32%), Positives = 36/62 (58%)
Frame = -1
Query: 739 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 560
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 559 RF 554
+F
Sbjct: 69 KF 70
>AF016582-1|AAC51736.1| 476|Homo sapiens Chk1 protein.
Length = 476
Score = 86.2 bits (204), Expect = 1e-16
Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 3/149 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L I THRDIK ENLL+D N+K+SDFG A + N L CG+ Y +PE
Sbjct: 120 YLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPE 177
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAE 203
+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++ K+ +
Sbjct: 178 LLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSA 237
Query: 202 CRKLITRILAP-LKMRVKIPQILADPWLN 119
L+ +IL R+ IP I D W N
Sbjct: 238 PLALLHKILVENPSARITIPDIKKDRWYN 266
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/62 (32%), Positives = 36/62 (58%)
Frame = -1
Query: 739 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 560
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 559 RF 554
+F
Sbjct: 69 KF 70
>AB032387-1|BAA84577.1| 476|Homo sapiens checkpoint kinase protein.
Length = 476
Score = 86.2 bits (204), Expect = 1e-16
Identities = 54/149 (36%), Positives = 78/149 (52%), Gaps = 3/149 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L I THRDIK ENLL+D N+K+SDFG A + N L CG+ Y +PE
Sbjct: 120 YLHGIGITHRDIKPENLLLDERDNLKISDFGLAT--VFRYNNRERLLNKMCGTLPYVAPE 177
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDD-TNYTQLLKQVQNKVSFPRE-PKVSAE 203
+LK + + DVWS G+VL A++ G LP+D ++ Q + K ++ K+ +
Sbjct: 178 LLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSA 237
Query: 202 CRKLITRILAP-LKMRVKIPQILADPWLN 119
L+ +IL R+ IP I D W N
Sbjct: 238 PLALLHKILVENPSARITIPDIKKDRWYN 266
Score = 33.9 bits (74), Expect = 0.77
Identities = 20/62 (32%), Positives = 36/62 (58%)
Frame = -1
Query: 739 LGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLI 560
L +T+G G+Y V++A + VA+KI+ +A + + +EI + K L HEN++
Sbjct: 11 LVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVD--CPENIKKEICINKMLNHENVV 68
Query: 559 RF 554
+F
Sbjct: 69 KF 70
>AF140507-1|AAD31507.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta protein.
Length = 588
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/151 (33%), Positives = 83/151 (54%), Gaps = 4/151 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL + G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNYVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKAKDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL 122
+ + + LITR+L + R+ +P+I PW+
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/139 (35%), Positives = 79/139 (56%), Gaps = 3/139 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K EN+L+D +N K++DFG + +G F T CGS YA+PE++ G Y
Sbjct: 139 HRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYA 193
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSF-PR--EPKVSAECRKLITR 182
+ D+WS GV+LYA++ G LPFDD + L K++ + + + P+ P V + + ++
Sbjct: 194 GPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQ- 252
Query: 181 ILAPLKMRVKIPQILADPW 125
+ P+K R I I W
Sbjct: 253 -VDPMK-RASIKDIREHEW 269
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/70 (31%), Positives = 41/70 (58%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y+LG T+G G++ VKV + +VA+KI+++ + + + REI+ +K +H +
Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 77
Query: 565 LIRFLQAIET 536
+I+ Q I T
Sbjct: 78 IIKLYQVIST 87
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 85.0 bits (201), Expect = 3e-16
Identities = 41/95 (43%), Positives = 60/95 (63%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K EN+L+D +N K++DFG + +G F T CGS YA+PE++ G Y
Sbjct: 163 HRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYA 217
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV 248
+ D+WS GV+LYA++ G LPFDD + L K++
Sbjct: 218 GPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKI 252
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/70 (31%), Positives = 41/70 (58%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y+LG T+G G++ VKV + +VA+KI+++ + + + REI+ +K +H +
Sbjct: 27 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 86
Query: 565 LIRFLQAIET 536
+I+ Q I T
Sbjct: 87 IIKLYQVIST 96
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 85.0 bits (201), Expect = 3e-16
Identities = 41/95 (43%), Positives = 60/95 (63%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K EN+L+D +N K++DFG + +G F T CGS YA+PE++ G Y
Sbjct: 139 HRDLKPENVLLDAHMNAKIADFGLSN---MMSDGEFL--RTSCGSPNYAAPEVISGRLYA 193
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV 248
+ D+WS GV+LYA++ G LPFDD + L K++
Sbjct: 194 GPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKI 228
Score = 43.2 bits (97), Expect = 0.001
Identities = 22/70 (31%), Positives = 41/70 (58%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y+LG T+G G++ VKV + +VA+KI+++ + + + REI+ +K +H +
Sbjct: 18 YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPH 77
Query: 565 LIRFLQAIET 536
+I+ Q I T
Sbjct: 78 IIKLYQVIST 87
>U79240-1|AAB50198.1| 458|Homo sapiens serine/threonine protein
kinase protein.
Length = 458
Score = 84.6 bits (200), Expect = 4e-16
Identities = 49/148 (33%), Positives = 82/148 (55%), Gaps = 1/148 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ +L+ + HRD K EN+++ IKL DFG A + K L TFCG+ Y +
Sbjct: 251 VGYLRLKDIIHRDFKDENIVIAEDFTIKLIDFGSAAYLERGK-----LFYTFCGTIEYCA 305
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAE 203
PE+L G PYR + ++WS+GV LY +V F++ + +L + V+ + P VS E
Sbjct: 306 PEVLMGNPYRGPELEMWSLGVTLYTLV-----FEENPFCELEETVEAAIHPPY--LVSKE 358
Query: 202 CRKLITRILAPL-KMRVKIPQILADPWL 122
L++ +L P+ + R + +++ DPW+
Sbjct: 359 LMSLVSGLLQPVPERRTTLEKLVTDPWV 386
>BC026060-1|AAH26060.1| 541|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 2,
beta protein.
Length = 541
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 4/151 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL 122
+ + + LITR+L + R+ +P+I PW+
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein
protein.
Length = 365
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 4/151 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 109 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 164
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 165 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 224
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL 122
+ + + LITR+L + R+ +P+I PW+
Sbjct: 225 AEDLKDLITRMLDKNPESRIVVPEIKLHPWV 255
>AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 1 protein.
Length = 588
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 4/151 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL 122
+ + + LITR+L + R+ +P+I PW+
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta 2 protein.
Length = 533
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 4/151 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL 122
+ + + LITR+L + R+ +P+I PW+
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 541
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 4/151 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL 122
+ + + LITR+L + R+ +P+I PW+
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF287631-1|AAK64601.1| 533|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase b2
protein.
Length = 533
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 4/151 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL 122
+ + + LITR+L + R+ +P+I PW+
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF287630-1|AAK64600.1| 588|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase b1
protein.
Length = 588
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 4/151 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL 122
+ + + LITR+L + R+ +P+I PW+
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-dependent
kinase kinase protein.
Length = 417
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 4/151 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 184 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 239
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 240 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 299
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL 122
+ + + LITR+L + R+ +P+I PW+
Sbjct: 300 AEDLKDLITRMLDKNPESRIVVPEIKLHPWV 330
>AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta-3 protein.
Length = 541
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 4/151 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL 122
+ + + LITR+L + R+ +P+I PW+
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEIKLHPWV 446
>AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein.
Length = 557
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/151 (33%), Positives = 82/151 (54%), Gaps = 4/151 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 301 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 356
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 357 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 416
Query: 211 SAECRKLITRIL-APLKMRVKIPQILADPWL 122
+ + + LITR+L + R+ +P+I PW+
Sbjct: 417 AEDLKDLITRMLDKNPESRIVVPEIKLHPWV 447
>AK058166-1|BAB71697.1| 128|Homo sapiens protein ( Homo sapiens
cDNA FLJ25437 fis, clone TST08312. ).
Length = 128
Score = 82.2 bits (194), Expect = 2e-15
Identities = 34/75 (45%), Positives = 55/75 (73%)
Frame = -1
Query: 763 VLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVK 584
+L GY LGRTIG GSY+ VKVA+S ++ VAIK++ + +AP D++ KFLPRE+ +++
Sbjct: 6 LLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRELSILR 65
Query: 583 GLKHENLIRFLQAIE 539
G++H +++ + IE
Sbjct: 66 GVRHPHIVHVFEFIE 80
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 81.4 bits (192), Expect = 4e-15
Identities = 48/149 (32%), Positives = 76/149 (51%), Gaps = 2/149 (1%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
++ + + HRD+K EN+ +K+ DFGF+ K + + TFCGS YA+
Sbjct: 184 VKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGE-----MLNTFCGSPPYAA 238
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSA 206
PE+ + Y D+W++GV+LY +V G +PF +L K + + S P P VS
Sbjct: 239 PELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVP--PHVSE 296
Query: 205 ECRKLITRILAPLKM-RVKIPQILADPWL 122
C +LI +L + R I I+ D W+
Sbjct: 297 PCHRLIRGVLQQIPTERYGIDCIMNDEWM 325
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 1/86 (1%)
Frame = -1
Query: 790 EAKTERKLTVLESHG-YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKK 614
+ K R++T+ + G Y + IGSG+++ VK+ +VAIKI+ K + ++
Sbjct: 58 DEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLD-QKTQR 116
Query: 613 FLPREIEVVKGLKHENLIRFLQAIET 536
L REI ++ L H N+IR + +ET
Sbjct: 117 LLSREISSMEKLHHPNIIRLYEVVET 142
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 80.2 bits (189), Expect = 9e-15
Identities = 45/137 (32%), Positives = 82/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RDIK ENL++D +IK++DFG + + +G A +TFC
Sbjct: 256 GAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFC 311
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FP
Sbjct: 312 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFP 370
Query: 226 REPKVSAECRKLITRIL 176
R +S E + L+ +L
Sbjct: 371 R--TLSPEAKSLLAGLL 385
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 80.2 bits (189), Expect = 9e-15
Identities = 45/137 (32%), Positives = 82/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RDIK ENL++D +IK++DFG + + +G A +TFC
Sbjct: 256 GAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFC 311
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FP
Sbjct: 312 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFP 370
Query: 226 REPKVSAECRKLITRIL 176
R +S E + L+ +L
Sbjct: 371 R--TLSPEAKSLLAGLL 385
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 80.2 bits (189), Expect = 9e-15
Identities = 45/137 (32%), Positives = 82/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RDIK ENL++D +IK++DFG + + +G A +TFC
Sbjct: 256 GAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGI--SDG--ATMKTFC 311
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + ++ FP
Sbjct: 312 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFP 370
Query: 226 REPKVSAECRKLITRIL 176
R +S E + L+ +L
Sbjct: 371 R--TLSPEAKSLLAGLL 385
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 79.0 bits (186), Expect = 2e-14
Identities = 47/170 (27%), Positives = 85/170 (50%), Gaps = 1/170 (0%)
Frame = -1
Query: 568 NLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
N + + + HRDIK ENLL+ +K++DFG++ + + T CG+ Y
Sbjct: 241 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCGTLDY 294
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 209
PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F V+
Sbjct: 295 LPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVT 352
Query: 208 AECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 353 EGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 402
Score = 44.0 bits (99), Expect = 7e-04
Identities = 22/82 (26%), Positives = 43/82 (52%)
Frame = -1
Query: 802 HSGVEAKTERKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDY 623
H + K +++ LE + +GR +G G + V +A + +A+K++ K Q
Sbjct: 115 HQNRKMKNQKEAVALED--FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAG 172
Query: 622 LKKFLPREIEVVKGLKHENLIR 557
++ L RE+E+ L+H N++R
Sbjct: 173 VEHQLRREVEIQSHLRHPNILR 194
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 47/170 (27%), Positives = 85/170 (50%), Gaps = 1/170 (0%)
Frame = -1
Query: 568 NLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
N + + + HRDIK ENLL+ +K++DFG++ + + T CG+ Y
Sbjct: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCGTLDY 295
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 209
PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F V+
Sbjct: 296 LPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVT 353
Query: 208 AECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
Score = 39.9 bits (89), Expect = 0.012
Identities = 18/63 (28%), Positives = 35/63 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 565 LIR 557
++R
Sbjct: 193 ILR 195
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 47/170 (27%), Positives = 85/170 (50%), Gaps = 1/170 (0%)
Frame = -1
Query: 568 NLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
N + + + HRDIK ENLL+ +K++DFG++ + + T CG+ Y
Sbjct: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCGTLDY 295
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 209
PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F V+
Sbjct: 296 LPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVT 353
Query: 208 AECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
Score = 39.9 bits (89), Expect = 0.012
Identities = 18/63 (28%), Positives = 35/63 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 565 LIR 557
++R
Sbjct: 193 ILR 195
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 47/170 (27%), Positives = 85/170 (50%), Gaps = 1/170 (0%)
Frame = -1
Query: 568 NLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
N + + + HRDIK ENLL+ +K++DFG++ + + T CG+ Y
Sbjct: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCGTLDY 295
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 209
PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F V+
Sbjct: 296 LPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVT 353
Query: 208 AECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
Score = 39.9 bits (89), Expect = 0.012
Identities = 18/63 (28%), Positives = 35/63 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 565 LIR 557
++R
Sbjct: 193 ILR 195
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 47/170 (27%), Positives = 85/170 (50%), Gaps = 1/170 (0%)
Frame = -1
Query: 568 NLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
N + + + HRDIK ENLL+ +K++DFG++ + + T CG+ Y
Sbjct: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCGTLDY 295
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 209
PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F V+
Sbjct: 296 LPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVT 353
Query: 208 AECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
Score = 39.9 bits (89), Expect = 0.012
Identities = 18/63 (28%), Positives = 35/63 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 565 LIR 557
++R
Sbjct: 193 ILR 195
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 47/170 (27%), Positives = 85/170 (50%), Gaps = 1/170 (0%)
Frame = -1
Query: 568 NLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
N + + + HRDIK ENLL+ +K++DFG++ + + T CG+ Y
Sbjct: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCGTLDY 295
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 209
PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F V+
Sbjct: 296 LPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVT 353
Query: 208 AECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
Score = 39.9 bits (89), Expect = 0.012
Identities = 18/63 (28%), Positives = 35/63 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 565 LIR 557
++R
Sbjct: 193 ILR 195
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 47/170 (27%), Positives = 85/170 (50%), Gaps = 1/170 (0%)
Frame = -1
Query: 568 NLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
N + + + HRDIK ENLL+ +K++DFG++ + + T CG+ Y
Sbjct: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCGTLDY 295
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 209
PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F V+
Sbjct: 296 LPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVT 353
Query: 208 AECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
Score = 39.9 bits (89), Expect = 0.012
Identities = 18/63 (28%), Positives = 35/63 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 565 LIR 557
++R
Sbjct: 193 ILR 195
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 47/170 (27%), Positives = 85/170 (50%), Gaps = 1/170 (0%)
Frame = -1
Query: 568 NLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
N + + + HRDIK ENLL+ +K++DFG++ + + T CG+ Y
Sbjct: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCGTLDY 295
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 209
PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F V+
Sbjct: 296 LPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVT 353
Query: 208 AECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
Score = 39.9 bits (89), Expect = 0.012
Identities = 18/63 (28%), Positives = 35/63 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 565 LIR 557
++R
Sbjct: 193 ILR 195
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 79.0 bits (186), Expect = 2e-14
Identities = 47/170 (27%), Positives = 85/170 (50%), Gaps = 1/170 (0%)
Frame = -1
Query: 568 NLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
N + + + HRDIK ENLL+ +K++DFG++ + + T CG+ Y
Sbjct: 242 NALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS------VHAPSSRRTTLCGTLDY 295
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVS 209
PE+++G + D+WS+GV+ Y + G+ PF+ Y + K++ ++V F V+
Sbjct: 296 LPPEMIEG-RMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRI-SRVEFTFPDFVT 353
Query: 208 AECRKLITRILA-PLKMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
R LI+R+L R + ++L PW+ N + + + +K S
Sbjct: 354 EGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKPSNCQNKESASKQS 403
Score = 39.9 bits (89), Expect = 0.012
Identities = 18/63 (28%), Positives = 35/63 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
+ +GR +G G + V +A + +A+K++ K Q ++ L RE+E+ L+H N
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPN 192
Query: 565 LIR 557
++R
Sbjct: 193 ILR 195
>AB004885-1|BAA20562.1| 787|Homo sapiens PKU-beta protein.
Length = 787
Score = 78.2 bits (184), Expect = 4e-14
Identities = 63/199 (31%), Positives = 93/199 (46%), Gaps = 16/199 (8%)
Frame = -1
Query: 568 NLIRFLQAIETT--HRDIKCENLLMDHGL---NIKLSDFGFARGHMKPKNGV--FALSET 410
N +R+L I+ H D+K N+L+ G IK++DFG ++ GV L+
Sbjct: 591 NALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMVLTSQ 650
Query: 409 FCGSYAYASPEIL---KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-- 245
G+Y Y PE K P DVWS+GV+ Y +YGR PF Q + Q
Sbjct: 651 GAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTI 710
Query: 244 ---NKVSFPREPKVSAECRKLITRILAPLKM-RVKIPQILADPWLNPNQQSKHDETDLQE 77
+V FP +P VS+E + I R LA K R + Q+ DP+L P+ + + +L
Sbjct: 711 LKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLACDPYLLPHMRRSNSSGNLHM 770
Query: 76 HAKTSKEEIKSVNIGTVTY 20
T+ S +I +TY
Sbjct: 771 AGLTASPTPPSSSI--ITY 787
>X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha
mRNA for protein kinase C alpha. ).
Length = 672
Score = 77.8 bits (183), Expect = 5e-14
Identities = 44/128 (34%), Positives = 76/128 (59%), Gaps = 3/128 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
FL +RD+K +N+++D +IK++DFG + HM +GV + TFCG+ Y +PE
Sbjct: 453 FLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHM--MDGV--TTRTFCGTPDYIAPE 508
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAE- 203
I+ PY + D W+ GV+LY ++ G+ PFD + +L + + ++ VS+P+ A
Sbjct: 509 IIAYQPY-GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVS 567
Query: 202 -CRKLITR 182
C+ L+T+
Sbjct: 568 ICKGLMTK 575
>BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 77.8 bits (183), Expect = 5e-14
Identities = 44/128 (34%), Positives = 76/128 (59%), Gaps = 3/128 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
FL +RD+K +N+++D +IK++DFG + HM +GV + TFCG+ Y +PE
Sbjct: 453 FLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHM--MDGV--TTRTFCGTPDYIAPE 508
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAE- 203
I+ PY + D W+ GV+LY ++ G+ PFD + +L + + ++ VS+P+ A
Sbjct: 509 IIAYQPY-GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVS 567
Query: 202 -CRKLITR 182
C+ L+T+
Sbjct: 568 ICKGLMTK 575
>BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 77.8 bits (183), Expect = 5e-14
Identities = 44/128 (34%), Positives = 76/128 (59%), Gaps = 3/128 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
FL +RD+K +N+++D +IK++DFG + HM +GV + TFCG+ Y +PE
Sbjct: 453 FLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHM--MDGV--TTRTFCGTPDYIAPE 508
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAE- 203
I+ PY + D W+ GV+LY ++ G+ PFD + +L + + ++ VS+P+ A
Sbjct: 509 IIAYQPY-GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVS 567
Query: 202 -CRKLITR 182
C+ L+T+
Sbjct: 568 ICKGLMTK 575
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 77.8 bits (183), Expect = 5e-14
Identities = 57/193 (29%), Positives = 92/193 (47%), Gaps = 14/193 (7%)
Frame = -1
Query: 655 IISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH------RDIKCENLLMDH 494
++ ++Q GD L E ++ + L L + A+ + H RDIK EN+L+D
Sbjct: 172 LVMEYQPGGDLLSLLNRYEDQLDENLIQFYLAELILAVHSVHLMGYVHRDIKPENILVDR 231
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILK-----GVPYRPQDSDVWS 329
+IKL DFG A K + ++ G+ Y +PE+L G D D WS
Sbjct: 232 TGHIKLVDFGSAA---KMNSNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDWWS 288
Query: 328 MGVVLYAIVYGRLPFDDTNYTQLLKQVQN---KVSFPREPKVSAECRKLITRILAPLKMR 158
+GV+ Y ++YGR PF + + + N + FP +PKVS++ LI +L K R
Sbjct: 289 VGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQKER 348
Query: 157 VKIPQILADPWLN 119
+K + P+ +
Sbjct: 349 LKFEGLCCHPFFS 361
>AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6
protein protein.
Length = 672
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/128 (33%), Positives = 77/128 (60%), Gaps = 3/128 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
FL +RD+K +N+++D +IK++DFG + HM +GV + TFCG+ Y +PE
Sbjct: 453 FLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHM--MDGV--TTRTFCGTPDYIAPE 508
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR--EPKVSA 206
I+ PY + D W+ GV+LY ++ G+ PFD + +L + + ++ VS+P+ + +
Sbjct: 509 IIAYQPY-GKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVS 567
Query: 205 ECRKLITR 182
C+ L+T+
Sbjct: 568 VCKGLMTK 575
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 77.8 bits (183), Expect = 5e-14
Identities = 57/193 (29%), Positives = 92/193 (47%), Gaps = 14/193 (7%)
Frame = -1
Query: 655 IISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH------RDIKCENLLMDH 494
++ ++Q GD L E ++ + L L + A+ + H RDIK EN+L+D
Sbjct: 172 LVMEYQPGGDLLSLLNRYEDQLDENLIQFYLAELILAVHSVHLMGYVHRDIKPENILVDR 231
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILK-----GVPYRPQDSDVWS 329
+IKL DFG A K + ++ G+ Y +PE+L G D D WS
Sbjct: 232 TGHIKLVDFGSAA---KMNSNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDWWS 288
Query: 328 MGVVLYAIVYGRLPFDDTNYTQLLKQVQN---KVSFPREPKVSAECRKLITRILAPLKMR 158
+GV+ Y ++YGR PF + + + N + FP +PKVS++ LI +L K R
Sbjct: 289 VGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQKER 348
Query: 157 VKIPQILADPWLN 119
+K + P+ +
Sbjct: 349 LKFEGLCCHPFFS 361
>AY209000-1|AAP43922.1| 482|Homo sapiens citron Rho-interacting
kinase short form protein.
Length = 482
Score = 77.8 bits (183), Expect = 5e-14
Identities = 57/193 (29%), Positives = 92/193 (47%), Gaps = 14/193 (7%)
Frame = -1
Query: 655 IISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFLQAIETTH------RDIKCENLLMDH 494
++ ++Q GD L E ++ + L L + A+ + H RDIK EN+L+D
Sbjct: 172 LVMEYQPGGDLLSLLNRYEDQLDENLIQFYLAELILAVHSVHLMGYLHRDIKPENILVDR 231
Query: 493 GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILK-----GVPYRPQDSDVWS 329
+IKL DFG A K + ++ G+ Y +PE+L G D D WS
Sbjct: 232 TGHIKLVDFGSAA---KMNSNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDWWS 288
Query: 328 MGVVLYAIVYGRLPFDDTNYTQLLKQVQN---KVSFPREPKVSAECRKLITRILAPLKMR 158
+GV+ Y ++YGR PF + + + N + FP +PKVS++ LI +L K R
Sbjct: 289 VGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQKER 348
Query: 157 VKIPQILADPWLN 119
+K + P+ +
Sbjct: 349 LKFEGLCCHPFFS 361
>BC071948-1|AAH71948.1| 97|Homo sapiens MARK4 protein protein.
Length = 97
Score = 77.4 bits (182), Expect = 6e-14
Identities = 37/81 (45%), Positives = 52/81 (64%)
Frame = -1
Query: 514 ENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDV 335
ENLL+D NIK++DFGF+ + + +TFCGS YA+PE+ +G Y + D+
Sbjct: 19 ENLLLDAEANIKIADFGFSNEFT-----LGSKLDTFCGSPPYAAPELFQGKKYDGPEVDI 73
Query: 334 WSMGVVLYAIVYGRLPFDDTN 272
WS+GV+LY +V G LPFD N
Sbjct: 74 WSLGVILYTLVSGSLPFDGHN 94
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 77.4 bits (182), Expect = 6e-14
Identities = 54/161 (33%), Positives = 82/161 (50%), Gaps = 2/161 (1%)
Frame = -1
Query: 598 IEVVKGLKHENLIRFLQAIETTHRDIKCENLLMD-HGLNIKLSDFGFARGHMKPKNGVFA 422
+++ GLKH + + L HRDIK +N+ + +G+ KL DFG AR N
Sbjct: 110 VQISLGLKHIHDRKIL------HRDIKAQNIFLSKNGMVAKLGDFGIAR----VLNNSME 159
Query: 421 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN 242
L+ T G+ Y SPEI + PY + +D+WS+G VLY + + PF+ N QL+ ++
Sbjct: 160 LARTCIGTPYYLSPEICQNKPYNNK-TDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQ 218
Query: 241 KVSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 122
P P S E LI+++ + R I IL P+L
Sbjct: 219 AHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFL 259
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 77.4 bits (182), Expect = 6e-14
Identities = 54/161 (33%), Positives = 82/161 (50%), Gaps = 2/161 (1%)
Frame = -1
Query: 598 IEVVKGLKHENLIRFLQAIETTHRDIKCENLLMD-HGLNIKLSDFGFARGHMKPKNGVFA 422
+++ GLKH + + L HRDIK +N+ + +G+ KL DFG AR N
Sbjct: 110 VQISLGLKHIHDRKIL------HRDIKAQNIFLSKNGMVAKLGDFGIAR----VLNNSME 159
Query: 421 LSETFCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN 242
L+ T G+ Y SPEI + PY + +D+WS+G VLY + + PF+ N QL+ ++
Sbjct: 160 LARTCIGTPYYLSPEICQNKPYNNK-TDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQ 218
Query: 241 KVSFPREPKVSAECRKLITRIL-APLKMRVKIPQILADPWL 122
P P S E LI+++ + R I IL P+L
Sbjct: 219 AHFAPISPGFSRELHSLISQLFQVSPRDRPSINSILKRPFL 259
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 76.6 bits (180), Expect = 1e-13
Identities = 54/188 (28%), Positives = 96/188 (51%), Gaps = 12/188 (6%)
Frame = -1
Query: 655 IISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF-------LQAIET---THRDIKCENL 506
+I+ APG L +F+ + + L+ E ++ F L + T HRD+K +N+
Sbjct: 77 MIAMEYAPGGTLAEFIQKRCNSL--LEEETILHFFVQILLALHHVHTHLILHRDLKTQNI 134
Query: 505 LMD-HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 329
L+D H + +K+ DFG ++ + K+ + + T C Y SPE+ +G PY Q SD+W+
Sbjct: 135 LLDKHRMVVKIGDFGISK-ILSSKSKAYTVVGTPC----YISPELCEGKPYN-QKSDIWA 188
Query: 328 MGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVK 152
+G VLY + + F+ N L+ ++ + P + S E R+L+ +L+ R
Sbjct: 189 LGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPP 248
Query: 151 IPQILADP 128
+ I+A P
Sbjct: 249 LSHIMAQP 256
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 76.6 bits (180), Expect = 1e-13
Identities = 54/188 (28%), Positives = 96/188 (51%), Gaps = 12/188 (6%)
Frame = -1
Query: 655 IISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF-------LQAIET---THRDIKCENL 506
+I+ APG L +F+ + + L+ E ++ F L + T HRD+K +N+
Sbjct: 77 MIAMEYAPGGTLAEFIQKRCNSL--LEEETILHFFVQILLALHHVHTHLILHRDLKTQNI 134
Query: 505 LMD-HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 329
L+D H + +K+ DFG ++ + K+ + + T C Y SPE+ +G PY Q SD+W+
Sbjct: 135 LLDKHRMVVKIGDFGISK-ILSSKSKAYTVVGTPC----YISPELCEGKPYN-QKSDIWA 188
Query: 328 MGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVK 152
+G VLY + + F+ N L+ ++ + P + S E R+L+ +L+ R
Sbjct: 189 LGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPP 248
Query: 151 IPQILADP 128
+ I+A P
Sbjct: 249 LSHIMAQP 256
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 76.6 bits (180), Expect = 1e-13
Identities = 54/188 (28%), Positives = 96/188 (51%), Gaps = 12/188 (6%)
Frame = -1
Query: 655 IISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF-------LQAIET---THRDIKCENL 506
+I+ APG L +F+ + + L+ E ++ F L + T HRD+K +N+
Sbjct: 77 MIAMEYAPGGTLAEFIQKRCNSL--LEEETILHFFVQILLALHHVHTHLILHRDLKTQNI 134
Query: 505 LMD-HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 329
L+D H + +K+ DFG ++ + K+ + + T C Y SPE+ +G PY Q SD+W+
Sbjct: 135 LLDKHRMVVKIGDFGISK-ILSSKSKAYTVVGTPC----YISPELCEGKPYN-QKSDIWA 188
Query: 328 MGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVK 152
+G VLY + + F+ N L+ ++ + P + S E R+L+ +L+ R
Sbjct: 189 LGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPP 248
Query: 151 IPQILADP 128
+ I+A P
Sbjct: 249 LSHIMAQP 256
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 76.6 bits (180), Expect = 1e-13
Identities = 54/188 (28%), Positives = 96/188 (51%), Gaps = 12/188 (6%)
Frame = -1
Query: 655 IISKFQAPGDYLKKFLPREIEVVKGLKHENLIRF-------LQAIET---THRDIKCENL 506
+I+ APG L +F+ + + L+ E ++ F L + T HRD+K +N+
Sbjct: 77 MIAMEYAPGGTLAEFIQKRCNSL--LEEETILHFFVQILLALHHVHTHLILHRDLKTQNI 134
Query: 505 LMD-HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYRPQDSDVWS 329
L+D H + +K+ DFG ++ + K+ + + T C Y SPE+ +G PY Q SD+W+
Sbjct: 135 LLDKHRMVVKIGDFGISK-ILSSKSKAYTVVGTPC----YISPELCEGKPYN-QKSDIWA 188
Query: 328 MGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECRKLITRILA-PLKMRVK 152
+G VLY + + F+ N L+ ++ + P + S E R+L+ +L+ R
Sbjct: 189 LGCVLYELASLKRAFEAANLPALVLKIMSGTFAPISDRYSPELRQLVLSLLSLEPAQRPP 248
Query: 151 IPQILADP 128
+ I+A P
Sbjct: 249 LSHIMAQP 256
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AF321388-1|AAL37218.1| 498|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 498
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/145 (33%), Positives = 79/145 (54%), Gaps = 4/145 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQI 140
+ + + LITR+L + R+ +P+I
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEI 440
>AF321386-1|AAL37216.1| 545|Homo sapiens CaMKK beta 1 isoform
protein.
Length = 545
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/145 (33%), Positives = 79/145 (54%), Gaps = 4/145 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQI 140
+ + + LITR+L + R+ +P+I
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEI 440
>AF321385-1|AAL37215.1| 490|Homo sapiens CaMKK beta 2 isoform
protein.
Length = 490
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/145 (33%), Positives = 79/145 (54%), Gaps = 4/145 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQI 140
+ + + LITR+L + R+ +P+I
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEI 440
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 76.6 bits (180), Expect = 1e-13
Identities = 42/137 (30%), Positives = 81/137 (59%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL++D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase 13
protein.
Length = 275
Score = 76.6 bits (180), Expect = 1e-13
Identities = 47/145 (32%), Positives = 83/145 (57%), Gaps = 3/145 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRDIK ENLL+ +K++DFG++ P+ +T CG+ Y PE+++G Y
Sbjct: 130 HRDIKPENLLLGFRGEVKIADFGWSVHTPLPER------KTMCGTLDYLPPEMIEGRTY- 182
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D+W +GV+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L
Sbjct: 183 DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLL 240
Query: 175 --APLKMRVKIPQILADPWLNPNQQ 107
PL+ R+ + QIL PW+ + +
Sbjct: 241 RYQPLE-RLPLAQILKHPWVQAHSR 264
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/83 (31%), Positives = 43/83 (51%)
Frame = -1
Query: 775 RKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREI 596
R+LTV + + +GR +G G + V +A + VA+K++ K Q + L+ L REI
Sbjct: 2 RRLTVDD---FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREI 58
Query: 595 EVVKGLKHENLIRFLQAIETTHR 527
E+ L+H N++R R
Sbjct: 59 EIQAHLQHPNILRLYNYFHDARR 81
>AB081337-1|BAC19841.1| 498|Homo sapiens Ca2+/calmodulin-dependent
protein kinase kinase beta-3x protein.
Length = 498
Score = 76.6 bits (180), Expect = 1e-13
Identities = 48/145 (33%), Positives = 79/145 (54%), Gaps = 4/145 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 300 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 355
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 356 PESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 415
Query: 211 SAECRKLITRIL-APLKMRVKIPQI 140
+ + + LITR+L + R+ +P+I
Sbjct: 416 AEDLKDLITRMLDKNPESRIVVPEI 440
>Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 76.2 bits (179), Expect = 1e-13
Identities = 40/127 (31%), Positives = 70/127 (55%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L ++ +RD+K EN+L+D +I L+DFG + +++ + + TFCG+ Y +PE
Sbjct: 307 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPE 362
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+L PY + D W +G VLY ++YG PF N ++ + NK +P ++ R
Sbjct: 363 VLHKQPY-DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSAR 420
Query: 196 KLITRIL 176
L+ +L
Sbjct: 421 HLLEGLL 427
>Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 76.2 bits (179), Expect = 1e-13
Identities = 40/127 (31%), Positives = 70/127 (55%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L ++ +RD+K EN+L+D +I L+DFG + +++ + + TFCG+ Y +PE
Sbjct: 212 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPE 267
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+L PY + D W +G VLY ++YG PF N ++ + NK +P ++ R
Sbjct: 268 VLHKQPY-DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSAR 325
Query: 196 KLITRIL 176
L+ +L
Sbjct: 326 HLLEGLL 332
>X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B
protein.
Length = 417
Score = 76.2 bits (179), Expect = 1e-13
Identities = 42/120 (35%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
+RD+K ENL++D +IK++DFG + + K+G A +TFCG+ Y +PE+L+ Y
Sbjct: 209 YRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTPEYLAPEVLEDNDY- 263
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR + E + L++ +L
Sbjct: 264 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR--TLGPEAKSLLSGLL 321
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 76.2 bits (179), Expect = 1e-13
Identities = 42/120 (35%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
+RD+K ENL++D +IK++DFG + + K+G A +TFCG+ Y +PE+L+ Y
Sbjct: 272 YRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTPEYLAPEVLEDNDY- 326
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR + E + L++ +L
Sbjct: 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR--TLGPEAKSLLSGLL 384
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 76.2 bits (179), Expect = 1e-13
Identities = 42/120 (35%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
+RD+K ENL++D +IK++DFG + + K+G A +TFCG+ Y +PE+L+ Y
Sbjct: 272 YRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTPEYLAPEVLEDNDY- 326
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR + E + L++ +L
Sbjct: 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR--TLGPEAKSLLSGLL 384
>BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 76.2 bits (179), Expect = 1e-13
Identities = 40/127 (31%), Positives = 70/127 (55%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L ++ +RD+K EN+L+D +I L+DFG + +++ + + TFCG+ Y +PE
Sbjct: 212 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPE 267
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+L PY + D W +G VLY ++YG PF N ++ + NK +P ++ R
Sbjct: 268 VLHKQPY-DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSAR 325
Query: 196 KLITRIL 176
L+ +L
Sbjct: 326 HLLEGLL 332
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 76.2 bits (179), Expect = 1e-13
Identities = 42/120 (35%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
+RD+K ENL++D +IK++DFG + + K+G A +TFCG+ Y +PE+L+ Y
Sbjct: 272 YRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTPEYLAPEVLEDNDY- 326
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR + E + L++ +L
Sbjct: 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR--TLGPEAKSLLSGLL 384
>BC000318-1|AAH00318.2| 266|Homo sapiens CAMKK2 protein protein.
Length = 266
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/145 (33%), Positives = 79/145 (54%), Gaps = 4/145 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
I +L + HRDIK NLL+ +IK++DFG + G AL G+ A+ +
Sbjct: 68 IEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEF----KGSDALLSNTVGTPAFMA 123
Query: 382 PEILKGVP--YRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNK-VSFPREPKV 212
PE L + + DVW+MGV LY V+G+ PF D L +++++ + FP +P +
Sbjct: 124 PESLSETCKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDI 183
Query: 211 SAECRKLITRIL-APLKMRVKIPQI 140
+ + + LITR+L + R+ +P+I
Sbjct: 184 AEDLKDLITRMLDKNPESRIVVPEI 208
>AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 76.2 bits (179), Expect = 1e-13
Identities = 40/127 (31%), Positives = 70/127 (55%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L ++ +RD+K EN+L+D +I L+DFG + +++ + + TFCG+ Y +PE
Sbjct: 307 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPE 362
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+L PY + D W +G VLY ++YG PF N ++ + NK +P ++ R
Sbjct: 363 VLHKQPY-DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSAR 420
Query: 196 KLITRIL 176
L+ +L
Sbjct: 421 HLLEGLL 427
>AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 526
Score = 76.2 bits (179), Expect = 1e-13
Identities = 40/127 (31%), Positives = 70/127 (55%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L ++ +RD+K EN+L+D +I L+DFG + +++ + + TFCG+ Y +PE
Sbjct: 307 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPE 362
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+L PY + D W +G VLY ++YG PF N ++ + NK +P ++ R
Sbjct: 363 VLHKQPY-DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSAR 420
Query: 196 KLITRIL 176
L+ +L
Sbjct: 421 HLLEGLL 427
>AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 445
Score = 76.2 bits (179), Expect = 1e-13
Identities = 40/127 (31%), Positives = 70/127 (55%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L ++ +RD+K EN+L+D +I L+DFG + +++ + + TFCG+ Y +PE
Sbjct: 226 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPE 281
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+L PY + D W +G VLY ++YG PF N ++ + NK +P ++ R
Sbjct: 282 VLHKQPY-DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSAR 339
Query: 196 KLITRIL 176
L+ +L
Sbjct: 340 HLLEGLL 346
>AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 431
Score = 76.2 bits (179), Expect = 1e-13
Identities = 40/127 (31%), Positives = 70/127 (55%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L ++ +RD+K EN+L+D +I L+DFG + +++ + + TFCG+ Y +PE
Sbjct: 212 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPE 267
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+L PY + D W +G VLY ++YG PF N ++ + NK +P ++ R
Sbjct: 268 VLHKQPY-DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSAR 325
Query: 196 KLITRIL 176
L+ +L
Sbjct: 326 HLLEGLL 332
>AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid
regulated kinase protein.
Length = 421
Score = 76.2 bits (179), Expect = 1e-13
Identities = 40/127 (31%), Positives = 70/127 (55%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L ++ +RD+K EN+L+D +I L+DFG + +++ + + TFCG+ Y +PE
Sbjct: 202 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPE 257
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+L PY + D W +G VLY ++YG PF N ++ + NK +P ++ R
Sbjct: 258 VLHKQPY-DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSAR 315
Query: 196 KLITRIL 176
L+ +L
Sbjct: 316 HLLEGLL 322
>AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protein
kinase protein.
Length = 431
Score = 76.2 bits (179), Expect = 1e-13
Identities = 40/127 (31%), Positives = 70/127 (55%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L ++ +RD+K EN+L+D +I L+DFG + +++ + + TFCG+ Y +PE
Sbjct: 212 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPE 267
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+L PY + D W +G VLY ++YG PF N ++ + NK +P ++ R
Sbjct: 268 VLHKQPY-DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSAR 325
Query: 196 KLITRIL 176
L+ +L
Sbjct: 326 HLLEGLL 332
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 76.2 bits (179), Expect = 1e-13
Identities = 42/120 (35%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
+RD+K ENL++D +IK++DFG + + K+G A +TFCG+ Y +PE+L+ Y
Sbjct: 272 YRDLKLENLMLDKDGHIKITDFGLCKEGI--KDG--ATMKTFCGTPEYLAPEVLEDNDY- 326
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D W +GVV+Y ++ GRLPF + ++ +L + + ++ FPR + E + L++ +L
Sbjct: 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPR--TLGPEAKSLLSGLL 384
>AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protein
kinase sgk protein.
Length = 431
Score = 76.2 bits (179), Expect = 1e-13
Identities = 40/127 (31%), Positives = 70/127 (55%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L ++ +RD+K EN+L+D +I L+DFG + +++ + + TFCG+ Y +PE
Sbjct: 212 YLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHN----STTSTFCGTPEYLAPE 267
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPKVSAECR 197
+L PY + D W +G VLY ++YG PF N ++ + NK +P ++ R
Sbjct: 268 VLHKQPY-DRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNK-PLQLKPNITNSAR 325
Query: 196 KLITRIL 176
L+ +L
Sbjct: 326 HLLEGLL 332
>AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens
cDNA FLJ16039 fis, clone ADRGL2001554, weakly similar
to SERINE/THREONINE-PROTEIN KINASE PLK (EC 2.7.1.-). ).
Length = 706
Score = 75.8 bits (178), Expect = 2e-13
Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 5/141 (3%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRD+K N+ +D L +K+ D G A +P +T CG+ Y +PEIL+ R
Sbjct: 160 HRDLKLGNIFLDENLEVKVGDLGLAAQLNEPNE----RKKTMCGTPNYIAPEILQSNDKR 215
Query: 352 --PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP-REPKVSAECRKLIT 185
+ D+W++GV+ Y ++ G+ PFD + +++ +N++SFP ++ +S + R I
Sbjct: 216 AYSYEVDIWAVGVITYTMLIGKAPFDGGSKEITYRKIRENELSFPIKDHHISHQARMFIR 275
Query: 184 RILAP-LKMRVKIPQILADPW 125
IL P R+ + Q++ P+
Sbjct: 276 SILNPDPTQRLTLEQMVQHPF 296
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 75.4 bits (177), Expect = 3e-13
Identities = 42/137 (30%), Positives = 80/137 (58%), Gaps = 1/137 (0%)
Frame = -1
Query: 583 GLKHENLIRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFC 404
G + + + +L + + +RD+K ENL+ D +IK++DFG + + A +TFC
Sbjct: 252 GAEIVSALDYLHSGKIVYRDLKLENLMRDKDGHIKITDFGLCKEGITDA----ATMKTFC 307
Query: 403 GSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFP 227
G+ Y +PE+L+ Y + D W +GVV+Y ++ GRLPF + ++ +L + + + FP
Sbjct: 308 GTPEYLAPEVLEDNDY-GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFP 366
Query: 226 REPKVSAECRKLITRIL 176
R +S++ + L++ +L
Sbjct: 367 R--TLSSDAKSLLSGLL 381
>BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 75.4 bits (177), Expect = 3e-13
Identities = 55/197 (27%), Positives = 99/197 (50%), Gaps = 13/197 (6%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLM---------DHGLNIKLSDFGFARGHMKPKNGVFALSET 410
I +L + HRD+K EN+++ + LNIK++DFG A +K ++ A+ +
Sbjct: 226 IAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQA 282
Query: 409 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVS 233
CG+ Y +PE++ Y Q D+WS+GVV+Y ++ G PF ++ +L + + + ++
Sbjct: 283 TCGTPIYMAPEVISAHDYS-QQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELH 341
Query: 232 FPREPKVS-AECRKLITRILAPL--KMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
F S ++C K + + L + R+ ++L + WL N+ S T++ E K
Sbjct: 342 FENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEW 401
Query: 61 KEEIKSVNIGTVTYDRK 11
K +SV T K
Sbjct: 402 KNNPESVEENTTEEKNK 418
Score = 49.6 bits (113), Expect = 1e-05
Identities = 26/70 (37%), Positives = 39/70 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y GR +G GS+ V A+ + AIK ++K +A G K L RE+ ++K +KHE+
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSVKHEH 174
Query: 565 LIRFLQAIET 536
+I Q ET
Sbjct: 175 IIHLEQVFET 184
>AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ35932 fis, clone TESTI2011286, weakly similar to
MYOSIN LIGHT CHAIN KINASE (EC 2.7.1.117). ).
Length = 514
Score = 75.4 bits (177), Expect = 3e-13
Identities = 55/197 (27%), Positives = 99/197 (50%), Gaps = 13/197 (6%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLM---------DHGLNIKLSDFGFARGHMKPKNGVFALSET 410
I +L + HRD+K EN+++ + LNIK++DFG A +K ++ A+ +
Sbjct: 226 IAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQA 282
Query: 409 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVS 233
CG+ Y +PE++ Y Q D+WS+GVV+Y ++ G PF ++ +L + + + ++
Sbjct: 283 TCGTPIYMAPEVISAHDYS-QQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELH 341
Query: 232 FPREPKVS-AECRKLITRILAPL--KMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
F S ++C K + + L + R+ ++L + WL N+ S T++ E K
Sbjct: 342 FENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEW 401
Query: 61 KEEIKSVNIGTVTYDRK 11
K +SV T K
Sbjct: 402 KNNPESVEENTTEEKNK 418
Score = 49.6 bits (113), Expect = 1e-05
Identities = 26/70 (37%), Positives = 39/70 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y GR +G GS+ V A+ + AIK ++K +A G K L RE+ ++K +KHE+
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSVKHEH 174
Query: 565 LIRFLQAIET 536
+I Q ET
Sbjct: 175 IIHLEQVFET 184
>AK000231-1|BAA91023.1| 244|Homo sapiens protein ( Homo sapiens
cDNA FLJ20224 fis, clone COLF5039. ).
Length = 244
Score = 75.4 bits (177), Expect = 3e-13
Identities = 45/126 (35%), Positives = 69/126 (54%), Gaps = 3/126 (2%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLM--DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAY 389
I + + HRD+K EN++ GL +KL+DFGF+ K T CGS AY
Sbjct: 127 ISYCHKLHVVHRDLKPENVVFFEKQGL-VKLTDFGFSNKFQPGKK-----LTTSCGSLAY 180
Query: 388 ASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFPREPKV 212
++PEIL G Y D+WS+GV+L+ +V + PF + N ++ L + + K + P V
Sbjct: 181 SAPEILLGDEYDAPAVDIWSLGVILFMLVCEQPPFQEANDSETLTMIMDCKYTVPSH--V 238
Query: 211 SAECRK 194
S EC++
Sbjct: 239 SKECKE 244
Score = 39.5 bits (88), Expect = 0.015
Identities = 22/70 (31%), Positives = 39/70 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y L +T+G G +A VK+A +VA+K+I K + L +E+ +K ++H N
Sbjct: 16 YDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKL-DTLATGHLFQEVRCMKLVQHPN 74
Query: 565 LIRFLQAIET 536
++R + I+T
Sbjct: 75 IVRLYEVIDT 84
>AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase 33
protein.
Length = 514
Score = 75.4 bits (177), Expect = 3e-13
Identities = 55/197 (27%), Positives = 99/197 (50%), Gaps = 13/197 (6%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLM---------DHGLNIKLSDFGFARGHMKPKNGVFALSET 410
I +L + HRD+K EN+++ + LNIK++DFG A +K ++ A+ +
Sbjct: 226 IAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLA---VKKQSRSEAMLQA 282
Query: 409 FCGSYAYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVS 233
CG+ Y +PE++ Y Q D+WS+GVV+Y ++ G PF ++ +L + + + ++
Sbjct: 283 TCGTPIYMAPEVISAHDYS-QQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELH 341
Query: 232 FPREPKVS-AECRKLITRILAPL--KMRVKIPQILADPWLNPNQQSKHDETDLQEHAKTS 62
F S ++C K + + L + R+ ++L + WL N+ S T++ E K
Sbjct: 342 FENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEW 401
Query: 61 KEEIKSVNIGTVTYDRK 11
K +SV T K
Sbjct: 402 KNNPESVEENTTEEKNK 418
Score = 49.6 bits (113), Expect = 1e-05
Identities = 26/70 (37%), Positives = 39/70 (55%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
Y GR +G GS+ V A+ + AIK ++K +A G K L RE+ ++K +KHE+
Sbjct: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKA-GSSAVKLLEREVNILKSVKHEH 174
Query: 565 LIRFLQAIET 536
+I Q ET
Sbjct: 175 IIHLEQVFET 184
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 74.9 bits (176), Expect = 3e-13
Identities = 50/156 (32%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L + HRD+ NLL+ +NIK++DFG A P + T CG+ Y SPE
Sbjct: 126 YLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHY----TLCGTPNYISPE 181
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSA 206
I + +SDVWS+G + Y ++ GR PFD T +K NKV + +S
Sbjct: 182 IATRSAH-GLESDVWSLGCMFYTLLIGRPPFD----TDTVKNTLNKVVLADYEMPTFLSI 236
Query: 205 ECRKLITRILAPLKM-RVKIPQILADPWLNPNQQSK 101
E + LI ++L R+ + +L P+++ N +K
Sbjct: 237 EAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTK 272
Score = 33.1 bits (72), Expect = 1.3
Identities = 19/72 (26%), Positives = 36/72 (50%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
+ +G +G GS+A V A S +VAIK+I K + + + E+++ LKH +
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVKNEVKIHCQLKHPS 71
Query: 565 LIRFLQAIETTH 530
++ E ++
Sbjct: 72 ILELYNYFEDSN 83
>Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamma
subunit protein.
Length = 406
Score = 74.9 bits (176), Expect = 3e-13
Identities = 51/155 (32%), Positives = 82/155 (52%), Gaps = 9/155 (5%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ FL A HRD+K EN+L+D + I+LSDFGF+ H++P + L CG+ Y +
Sbjct: 141 VSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFS-CHLEPGEKLREL----CGTPGYLA 195
Query: 382 PEILK-----GVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFP 227
PEILK P ++ D+W+ GV+L+ ++ G PF +L+ + Q + S P
Sbjct: 196 PEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSP 255
Query: 226 REPKVSAECRKLITRIL-APLKMRVKIPQILADPW 125
S+ + LI+R+L + R+ Q L P+
Sbjct: 256 EWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPF 290
>X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta II. ).
Length = 673
Score = 74.9 bits (176), Expect = 3e-13
Identities = 41/128 (32%), Positives = 80/128 (62%), Gaps = 3/128 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
FLQ+ +RD+K +N+++D +IK++DFG + ++ +GV ++TFCG+ Y +PE
Sbjct: 456 FLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI--WDGV--TTKTFCGTPDYIAPE 511
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR--EPKVSA 206
I+ PY + D W+ GV+LY ++ G+ PF+ + +L + + ++ V++P+ + A
Sbjct: 512 IIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVA 570
Query: 205 ECRKLITR 182
C+ L+T+
Sbjct: 571 ICKGLMTK 578
>X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta I. ).
Length = 671
Score = 74.9 bits (176), Expect = 3e-13
Identities = 41/128 (32%), Positives = 80/128 (62%), Gaps = 3/128 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
FLQ+ +RD+K +N+++D +IK++DFG + ++ +GV ++TFCG+ Y +PE
Sbjct: 456 FLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI--WDGV--TTKTFCGTPDYIAPE 511
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR--EPKVSA 206
I+ PY + D W+ GV+LY ++ G+ PF+ + +L + + ++ V++P+ + A
Sbjct: 512 IIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVA 570
Query: 205 ECRKLITR 182
C+ L+T+
Sbjct: 571 ICKGLMTK 578
>M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase
protein.
Length = 406
Score = 74.9 bits (176), Expect = 3e-13
Identities = 51/155 (32%), Positives = 82/155 (52%), Gaps = 9/155 (5%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ FL A HRD+K EN+L+D + I+LSDFGF+ H++P + L CG+ Y +
Sbjct: 141 VSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFS-CHLEPGEKLREL----CGTPGYLA 195
Query: 382 PEILK-----GVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFP 227
PEILK P ++ D+W+ GV+L+ ++ G PF +L+ + Q + S P
Sbjct: 196 PEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSP 255
Query: 226 REPKVSAECRKLITRIL-APLKMRVKIPQILADPW 125
S+ + LI+R+L + R+ Q L P+
Sbjct: 256 EWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPF 290
>M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II
type protein.
Length = 673
Score = 74.9 bits (176), Expect = 3e-13
Identities = 41/128 (32%), Positives = 80/128 (62%), Gaps = 3/128 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
FLQ+ +RD+K +N+++D +IK++DFG + ++ +GV ++TFCG+ Y +PE
Sbjct: 456 FLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI--WDGV--TTKTFCGTPDYIAPE 511
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR--EPKVSA 206
I+ PY + D W+ GV+LY ++ G+ PF+ + +L + + ++ V++P+ + A
Sbjct: 512 IIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVA 570
Query: 205 ECRKLITR 182
C+ L+T+
Sbjct: 571 ICKGLMTK 578
>D50927-1|BAA09486.2| 801|Homo sapiens KIAA0137 protein protein.
Length = 801
Score = 74.9 bits (176), Expect = 3e-13
Identities = 62/199 (31%), Positives = 93/199 (46%), Gaps = 16/199 (8%)
Frame = -1
Query: 568 NLIRFLQAIETT--HRDIKCENLLMDHGL---NIKLSDFGFARGHMKPKNGVFALSETF- 407
N +R+L I+ H D+K N+L+ G IK++DFG ++ GV + T
Sbjct: 605 NALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQ 664
Query: 406 -CGSYAYASPEIL---KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-- 245
G+Y Y PE K P DVWS+GV+ + +YGR PF Q + Q
Sbjct: 665 GAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTI 724
Query: 244 ---NKVSFPREPKVSAECRKLITRILAPLKM-RVKIPQILADPWLNPNQQSKHDETDLQE 77
+V FP +P VS+E + I R LA K R + Q+ DP+L P+ + + +L
Sbjct: 725 LKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHM 784
Query: 76 HAKTSKEEIKSVNIGTVTY 20
T+ S +I +TY
Sbjct: 785 AGLTASPTPPSSSI--ITY 801
>BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta 1
protein.
Length = 673
Score = 74.9 bits (176), Expect = 3e-13
Identities = 41/128 (32%), Positives = 80/128 (62%), Gaps = 3/128 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
FLQ+ +RD+K +N+++D +IK++DFG + ++ +GV ++TFCG+ Y +PE
Sbjct: 456 FLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI--WDGV--TTKTFCGTPDYIAPE 511
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR--EPKVSA 206
I+ PY + D W+ GV+LY ++ G+ PF+ + +L + + ++ V++P+ + A
Sbjct: 512 IIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVA 570
Query: 205 ECRKLITR 182
C+ L+T+
Sbjct: 571 ICKGLMTK 578
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 74.9 bits (176), Expect = 3e-13
Identities = 50/156 (32%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L + HRD+ NLL+ +NIK++DFG A P + T CG+ Y SPE
Sbjct: 126 YLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHY----TLCGTPNYISPE 181
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSA 206
I + +SDVWS+G + Y ++ GR PFD T +K NKV + +S
Sbjct: 182 IATRSAH-GLESDVWSLGCMFYTLLIGRPPFD----TDTVKNTLNKVVLADYEMPSFLSI 236
Query: 205 ECRKLITRILAPLKM-RVKIPQILADPWLNPNQQSK 101
E + LI ++L R+ + +L P+++ N +K
Sbjct: 237 EAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTK 272
Score = 33.1 bits (72), Expect = 1.3
Identities = 19/72 (26%), Positives = 36/72 (50%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
+ +G +G GS+A V A S +VAIK+I K + + + E+++ LKH +
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71
Query: 565 LIRFLQAIETTH 530
++ E ++
Sbjct: 72 ILELYNYFEDSN 83
>BC032657-1|AAH32657.1| 766|Homo sapiens tousled-like kinase 1
protein.
Length = 766
Score = 74.9 bits (176), Expect = 3e-13
Identities = 62/199 (31%), Positives = 93/199 (46%), Gaps = 16/199 (8%)
Frame = -1
Query: 568 NLIRFLQAIETT--HRDIKCENLLMDHGL---NIKLSDFGFARGHMKPKNGVFALSETF- 407
N +R+L I+ H D+K N+L+ G IK++DFG ++ GV + T
Sbjct: 570 NALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQ 629
Query: 406 -CGSYAYASPEIL---KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-- 245
G+Y Y PE K P DVWS+GV+ + +YGR PF Q + Q
Sbjct: 630 GAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTI 689
Query: 244 ---NKVSFPREPKVSAECRKLITRILAPLKM-RVKIPQILADPWLNPNQQSKHDETDLQE 77
+V FP +P VS+E + I R LA K R + Q+ DP+L P+ + + +L
Sbjct: 690 LKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHM 749
Query: 76 HAKTSKEEIKSVNIGTVTY 20
T+ S +I +TY
Sbjct: 750 AGLTASPTPPSSSI--ITY 766
>BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase,
gamma 2 (testis) protein.
Length = 406
Score = 74.9 bits (176), Expect = 3e-13
Identities = 51/155 (32%), Positives = 82/155 (52%), Gaps = 9/155 (5%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ FL A HRD+K EN+L+D + I+LSDFGF+ H++P + L CG+ Y +
Sbjct: 141 VSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFS-CHLEPGEKLREL----CGTPGYLA 195
Query: 382 PEILK-----GVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFP 227
PEILK P ++ D+W+ GV+L+ ++ G PF +L+ + Q + S P
Sbjct: 196 PEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSP 255
Query: 226 REPKVSAECRKLITRIL-APLKMRVKIPQILADPW 125
S+ + LI+R+L + R+ Q L P+
Sbjct: 256 EWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPF 290
>AF246219-1|AAF71263.1| 549|Homo sapiens SNARE protein kinase SNAK
protein.
Length = 549
Score = 74.9 bits (176), Expect = 3e-13
Identities = 62/199 (31%), Positives = 93/199 (46%), Gaps = 16/199 (8%)
Frame = -1
Query: 568 NLIRFLQAIETT--HRDIKCENLLMDHGL---NIKLSDFGFARGHMKPKNGVFALSETF- 407
N +R+L I+ H D+K N+L+ G IK++DFG ++ GV + T
Sbjct: 353 NALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQ 412
Query: 406 -CGSYAYASPEIL---KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-- 245
G+Y Y PE K P DVWS+GV+ + +YGR PF Q + Q
Sbjct: 413 GAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTI 472
Query: 244 ---NKVSFPREPKVSAECRKLITRILAPLKM-RVKIPQILADPWLNPNQQSKHDETDLQE 77
+V FP +P VS+E + I R LA K R + Q+ DP+L P+ + + +L
Sbjct: 473 LKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHM 532
Query: 76 HAKTSKEEIKSVNIGTVTY 20
T+ S +I +TY
Sbjct: 533 AGLTASPTPPSSSI--ITY 549
>AF162666-1|AAF03094.1| 718|Homo sapiens tousled-like kinase 1
protein.
Length = 718
Score = 74.9 bits (176), Expect = 3e-13
Identities = 62/199 (31%), Positives = 93/199 (46%), Gaps = 16/199 (8%)
Frame = -1
Query: 568 NLIRFLQAIETT--HRDIKCENLLMDHGL---NIKLSDFGFARGHMKPKNGVFALSETF- 407
N +R+L I+ H D+K N+L+ G IK++DFG ++ GV + T
Sbjct: 522 NALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQ 581
Query: 406 -CGSYAYASPEIL---KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-- 245
G+Y Y PE K P DVWS+GV+ + +YGR PF Q + Q
Sbjct: 582 GAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTI 641
Query: 244 ---NKVSFPREPKVSAECRKLITRILAPLKM-RVKIPQILADPWLNPNQQSKHDETDLQE 77
+V FP +P VS+E + I R LA K R + Q+ DP+L P+ + + +L
Sbjct: 642 LKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHM 701
Query: 76 HAKTSKEEIKSVNIGTVTY 20
T+ S +I +TY
Sbjct: 702 AGLTASPTPPSSSI--ITY 718
>AC010092-1|AAY15077.1| 376|Homo sapiens unknown protein.
Length = 376
Score = 74.9 bits (176), Expect = 3e-13
Identities = 62/199 (31%), Positives = 93/199 (46%), Gaps = 16/199 (8%)
Frame = -1
Query: 568 NLIRFLQAIETT--HRDIKCENLLMDHGL---NIKLSDFGFARGHMKPKNGVFALSETF- 407
N +R+L I+ H D+K N+L+ G IK++DFG ++ GV + T
Sbjct: 180 NALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVDGMDLTSQ 239
Query: 406 -CGSYAYASPEIL---KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-- 245
G+Y Y PE K P DVWS+GV+ + +YGR PF Q + Q
Sbjct: 240 GAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTI 299
Query: 244 ---NKVSFPREPKVSAECRKLITRILAPLKM-RVKIPQILADPWLNPNQQSKHDETDLQE 77
+V FP +P VS+E + I R LA K R + Q+ DP+L P+ + + +L
Sbjct: 300 LKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHM 359
Query: 76 HAKTSKEEIKSVNIGTVTY 20
T+ S +I +TY
Sbjct: 360 AGLTASPTPPSSSI--ITY 376
>AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (5'
partial) splice form_ protein.
Length = 496
Score = 74.9 bits (176), Expect = 3e-13
Identities = 41/128 (32%), Positives = 80/128 (62%), Gaps = 3/128 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
FLQ+ +RD+K +N+++D +IK++DFG + ++ +GV ++TFCG+ Y +PE
Sbjct: 279 FLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI--WDGV--TTKTFCGTPDYIAPE 334
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR--EPKVSA 206
I+ PY + D W+ GV+LY ++ G+ PF+ + +L + + ++ V++P+ + A
Sbjct: 335 IIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVA 393
Query: 205 ECRKLITR 182
C+ L+T+
Sbjct: 394 ICKGLMTK 401
>AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (5'
partial) splice form_1 protein.
Length = 494
Score = 74.9 bits (176), Expect = 3e-13
Identities = 41/128 (32%), Positives = 80/128 (62%), Gaps = 3/128 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
FLQ+ +RD+K +N+++D +IK++DFG + ++ +GV ++TFCG+ Y +PE
Sbjct: 279 FLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI--WDGV--TTKTFCGTPDYIAPE 334
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPR--EPKVSA 206
I+ PY + D W+ GV+LY ++ G+ PF+ + +L + + ++ V++P+ + A
Sbjct: 335 IIAYQPY-GKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVA 393
Query: 205 ECRKLITR 182
C+ L+T+
Sbjct: 394 ICKGLMTK 401
>AB209055-1|BAD92292.1| 272|Homo sapiens phosphorylase kinase,
gamma 2 (testis) variant protein.
Length = 272
Score = 74.9 bits (176), Expect = 3e-13
Identities = 51/155 (32%), Positives = 82/155 (52%), Gaps = 9/155 (5%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ FL A HRD+K EN+L+D + I+LSDFGF+ H++P + L CG+ Y +
Sbjct: 7 VSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFS-CHLEPGEKLREL----CGTPGYLA 61
Query: 382 PEILK-----GVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV---QNKVSFP 227
PEILK P ++ D+W+ GV+L+ ++ G PF +L+ + Q + S P
Sbjct: 62 PEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSP 121
Query: 226 REPKVSAECRKLITRIL-APLKMRVKIPQILADPW 125
S+ + LI+R+L + R+ Q L P+
Sbjct: 122 EWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPF 156
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 74.9 bits (176), Expect = 3e-13
Identities = 50/156 (32%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPE 377
+L + HRD+ NLL+ +NIK++DFG A P + T CG+ Y SPE
Sbjct: 126 YLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHY----TLCGTPNYISPE 181
Query: 376 ILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKV---SFPREPKVSA 206
I + +SDVWS+G + Y ++ GR PFD T +K NKV + +S
Sbjct: 182 IATRSAH-GLESDVWSLGCMFYTLLIGRPPFD----TDTVKNTLNKVVLADYEMPTFLSI 236
Query: 205 ECRKLITRILAPLKM-RVKIPQILADPWLNPNQQSK 101
E + LI ++L R+ + +L P+++ N +K
Sbjct: 237 EAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTK 272
Score = 33.5 bits (73), Expect = 1.0
Identities = 19/72 (26%), Positives = 36/72 (50%)
Frame = -1
Query: 745 YMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHEN 566
+ +G +G GS+A V A S +VAIK+I K + + + E+++ LKH +
Sbjct: 12 FKVGNLLGKGSFAGVYRAESIHSGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPS 71
Query: 565 LIRFLQAIETTH 530
++ E ++
Sbjct: 72 ILELYNYFEDSN 83
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 74.5 bits (175), Expect = 4e-13
Identities = 43/113 (38%), Positives = 67/113 (59%), Gaps = 1/113 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ FL +RD+K +N+L+DH + KL+DFG + + NGV + TFCG+ Y +
Sbjct: 466 LMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI--CNGV--TTATFCGTPDYIA 521
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 227
PEIL+ + Y P D W+MGV+LY ++ G PF+ N L + + N +V +P
Sbjct: 522 PEILQEMLYGPA-VDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYP 573
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 74.5 bits (175), Expect = 4e-13
Identities = 43/113 (38%), Positives = 67/113 (59%), Gaps = 1/113 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+ FL +RD+K +N+L+DH + KL+DFG + + NGV + TFCG+ Y +
Sbjct: 467 LMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI--CNGV--TTATFCGTPDYIA 522
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQN-KVSFP 227
PEIL+ + Y P D W+MGV+LY ++ G PF+ N L + + N +V +P
Sbjct: 523 PEILQEMLYGPA-VDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYP 574
>U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-dependent
protein kinase II protein.
Length = 315
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 186
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 187 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 245
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 246 KNLINQMLTINPAK-RITADQALKHPWV 272
>L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-dependent
protein kinase isoform A protein.
Length = 306
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 64 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 119
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 120 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGTYDFPSPEWDTVTPEA 178
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 179 KNLINQMLTINPAK-RITADQALKHPWV 205
>BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 73.7 bits (173), Expect = 8e-13
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMD--HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+L HRDIK +N+L++ GL +K+SDFG + K G+ +ETF G+ Y +
Sbjct: 327 YLHDNHIVHRDIKGDNVLINTFSGL-LKISDFGTS----KRLAGITPCTETFTGTLQYMA 381
Query: 382 PEIL-KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQVQNKVSFPREPKV 212
PEI+ +G + +D+WS+G + + GR PF + Q + + KV P +
Sbjct: 382 PEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSL 441
Query: 211 SAECRKLITRILAP-LKMRVKIPQILADPWLNPNQQSK 101
SAE + + R P ++R +L DP+L P ++S+
Sbjct: 442 SAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSR 479
Score = 30.7 bits (66), Expect = 7.2
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = -1
Query: 727 IGSGSYATVKVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 551
+G G+Y V A DRH ++AIK I + + + L EI + + L+H+N++R+L
Sbjct: 220 LGKGTYGVV-YAGRDRHTRVRIAIKEIPERDSR---FSQPLHEEIALHRRLRHKNIVRYL 275
>BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein.
Length = 854
Score = 73.7 bits (173), Expect = 8e-13
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMD--HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+L HRDIK +N+L++ GL +K+SDFG + K G+ +ETF G+ Y +
Sbjct: 327 YLHDNHIVHRDIKGDNVLINTFSGL-LKISDFGTS----KRLAGITPCTETFTGTLQYMA 381
Query: 382 PEIL-KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQVQNKVSFPREPKV 212
PEI+ +G + +D+WS+G + + GR PF + Q + + KV P +
Sbjct: 382 PEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSL 441
Query: 211 SAECRKLITRILAP-LKMRVKIPQILADPWLNPNQQSK 101
SAE + + R P ++R +L DP+L P ++S+
Sbjct: 442 SAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSR 479
Score = 30.7 bits (66), Expect = 7.2
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = -1
Query: 727 IGSGSYATVKVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 551
+G G+Y V A DRH ++AIK I + + + L EI + + L+H+N++R+L
Sbjct: 220 LGKGTYGVV-YAGRDRHTRVRIAIKEIPERDSR---FSQPLHEEIALHRRLRHKNIVRYL 275
>BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein.
Length = 441
Score = 73.7 bits (173), Expect = 8e-13
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMD--HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+L HRDIK +N+L++ GL +K+SDFG + K G+ +ETF G+ Y +
Sbjct: 230 YLHDNHIVHRDIKGDNVLINTFSGL-LKISDFGTS----KRLAGITPCTETFTGTLQYMA 284
Query: 382 PEIL-KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQVQNKVSFPREPKV 212
PEI+ +G + +D+WS+G + + GR PF + Q + + KV P +
Sbjct: 285 PEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSL 344
Query: 211 SAECRKLITRILAP-LKMRVKIPQILADPWLNPNQQSK 101
SAE + + R P ++R +L DP+L P ++S+
Sbjct: 345 SAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSR 382
Score = 30.7 bits (66), Expect = 7.2
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = -1
Query: 727 IGSGSYATVKVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 551
+G G+Y V A DRH ++AIK I + + + L EI + + L+H+N++R+L
Sbjct: 123 LGKGTYGVV-YAGRDRHTRVRIAIKEIPERDSR---FSQPLHEEIALHRRLRHKNIVRYL 178
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 73.7 bits (173), Expect = 8e-13
Identities = 47/145 (32%), Positives = 82/145 (56%), Gaps = 3/145 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRDIK ENLL+ +K++DFG++ H +T CG+ Y PE+++G Y
Sbjct: 130 HRDIKPENLLLGFRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY- 182
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D+W +GV+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L
Sbjct: 183 DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLL 240
Query: 175 --APLKMRVKIPQILADPWLNPNQQ 107
PL+ R+ + QIL PW+ + +
Sbjct: 241 RYQPLE-RLPLAQILKHPWVQAHSR 264
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/83 (31%), Positives = 43/83 (51%)
Frame = -1
Query: 775 RKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREI 596
R+LTV + + +GR +G G + V +A + VA+K++ K Q + L+ L REI
Sbjct: 2 RRLTVDD---FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREI 58
Query: 595 EVVKGLKHENLIRFLQAIETTHR 527
E+ L+H N++R R
Sbjct: 59 EIQAHLQHPNILRLYNYFHDARR 81
>BC034044-1|AAH34044.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 186
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 187 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 245
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 246 KNLINQMLTINPAK-RITADQALKHPWV 272
>BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein.
Length = 453
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 66 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 121
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 122 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 180
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 181 KNLINQMLTINPAK-RITADQALKHPWV 207
>BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein.
Length = 797
Score = 73.7 bits (173), Expect = 8e-13
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMD--HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+L HRDIK +N+L++ GL +K+SDFG + K G+ +ETF G+ Y +
Sbjct: 484 YLHDNHIVHRDIKGDNVLINTFSGL-LKISDFGTS----KRLAGITPCTETFTGTLQYMA 538
Query: 382 PEIL-KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQVQNKVSFPREPKV 212
PEI+ +G + +D+WS+G + + GR PF + Q + + KV P +
Sbjct: 539 PEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSL 598
Query: 211 SAECRKLITRILAP-LKMRVKIPQILADPWLNPNQQSK 101
SAE + + R P ++R +L DP+L P ++S+
Sbjct: 599 SAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSR 636
Score = 30.7 bits (66), Expect = 7.2
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = -1
Query: 727 IGSGSYATVKVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 551
+G G+Y V A DRH ++AIK I + + + L EI + + L+H+N++R+L
Sbjct: 377 LGKGTYGVV-YAGRDRHTRVRIAIKEIPERDSR---FSQPLHEEIALHRRLRHKNIVRYL 432
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 73.7 bits (173), Expect = 8e-13
Identities = 47/145 (32%), Positives = 82/145 (56%), Gaps = 3/145 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRDIK ENLL+ +K++DFG++ H +T CG+ Y PE+++G Y
Sbjct: 161 HRDIKPENLLLGFRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY- 213
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D+W +GV+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L
Sbjct: 214 DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLL 271
Query: 175 --APLKMRVKIPQILADPWLNPNQQ 107
PL+ R+ + QIL PW+ + +
Sbjct: 272 RYQPLE-RLPLAQILKHPWVQAHSR 295
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/83 (31%), Positives = 43/83 (51%)
Frame = -1
Query: 775 RKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREI 596
R+LTV + + +GR +G G + V +A + VA+K++ K Q + L+ L REI
Sbjct: 33 RRLTVDD---FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREI 89
Query: 595 EVVKGLKHENLIRFLQAIETTHR 527
E+ L+H N++R R
Sbjct: 90 EIQAHLQHPNILRLYNYFHDARR 112
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 73.7 bits (173), Expect = 8e-13
Identities = 47/145 (32%), Positives = 82/145 (56%), Gaps = 3/145 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRDIK ENLL+ +K++DFG++ H +T CG+ Y PE+++G Y
Sbjct: 145 HRDIKPENLLLGFRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY- 197
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D+W +GV+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L
Sbjct: 198 DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLL 255
Query: 175 --APLKMRVKIPQILADPWLNPNQQ 107
PL+ R+ + QIL PW+ + +
Sbjct: 256 RYQPLE-RLPLAQILKHPWVQAHSR 279
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/83 (31%), Positives = 43/83 (51%)
Frame = -1
Query: 775 RKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREI 596
R+LTV + + +GR +G G + V +A + VA+K++ K Q + L+ L REI
Sbjct: 17 RRLTVDD---FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREI 73
Query: 595 EVVKGLKHENLIRFLQAIETTHR 527
E+ L+H N++R R
Sbjct: 74 EIQAHLQHPNILRLYNYFHDARR 96
>AL713896-5|CAI13790.1| 529|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 529
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 186
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 187 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 245
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 246 KNLINQMLTINPAK-RITADQALKHPWV 272
>AL713896-4|CAI13789.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 186
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 187 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 245
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 246 KNLINQMLTINPAK-RITADQALKHPWV 272
>AL713896-3|CAI13791.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 186
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 187 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 245
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 246 KNLINQMLTINPAK-RITADQALKHPWV 272
>AL713896-2|CAI13788.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 186
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 187 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 245
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 246 KNLINQMLTINPAK-RITADQALKHPWV 272
>AL713896-1|CAI13787.1| 453|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 453
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 66 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 121
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 122 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 180
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 181 KNLINQMLTINPAK-RITADQALKHPWV 207
>AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 797
Score = 73.7 bits (173), Expect = 8e-13
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMD--HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+L HRDIK +N+L++ GL +K+SDFG + K G+ +ETF G+ Y +
Sbjct: 484 YLHDNHIVHRDIKGDNVLINTFSGL-LKISDFGTS----KRLAGITPCTETFTGTLQYMA 538
Query: 382 PEIL-KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQVQNKVSFPREPKV 212
PEI+ +G + +D+WS+G + + GR PF + Q + + KV P +
Sbjct: 539 PEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSL 598
Query: 211 SAECRKLITRILAP-LKMRVKIPQILADPWLNPNQQSK 101
SAE + + R P ++R +L DP+L P ++S+
Sbjct: 599 SAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSR 636
Score = 30.7 bits (66), Expect = 7.2
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = -1
Query: 727 IGSGSYATVKVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 551
+G G+Y V A DRH ++AIK I + + + L EI + + L+H+N++R+L
Sbjct: 377 LGKGTYGVV-YAGRDRHTRVRIAIKEIPERDSR---FSQPLHEEIALHRRLRHKNIVRYL 432
>AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1288
Score = 73.7 bits (173), Expect = 8e-13
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMD--HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+L HRDIK +N+L++ GL +K+SDFG + K G+ +ETF G+ Y +
Sbjct: 761 YLHDNHIVHRDIKGDNVLINTFSGL-LKISDFGTS----KRLAGITPCTETFTGTLQYMA 815
Query: 382 PEIL-KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQVQNKVSFPREPKV 212
PEI+ +G + +D+WS+G + + GR PF + Q + + KV P +
Sbjct: 816 PEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSL 875
Query: 211 SAECRKLITRILAP-LKMRVKIPQILADPWLNPNQQSK 101
SAE + + R P ++R +L DP+L P ++S+
Sbjct: 876 SAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSR 913
Score = 30.7 bits (66), Expect = 7.2
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = -1
Query: 727 IGSGSYATVKVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 551
+G G+Y V A DRH ++AIK I + + + L EI + + L+H+N++R+L
Sbjct: 654 LGKGTYGVV-YAGRDRHTRVRIAIKEIPERDSR---FSQPLHEEIALHRRLRHKNIVRYL 709
>AL596247-5|CAI13965.1| 529|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 529
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 186
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 187 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 245
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 246 KNLINQMLTINPAK-RITADQALKHPWV 272
>AL596247-4|CAI13966.1| 495|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 495
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 186
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 187 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 245
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 246 KNLINQMLTINPAK-RITADQALKHPWV 272
>AL596247-3|CAI13968.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 186
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 187 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 245
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 246 KNLINQMLTINPAK-RITADQALKHPWV 272
>AL596247-2|CAI13967.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 131 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 186
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 187 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 245
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 246 KNLINQMLTINPAK-RITADQALKHPWV 272
>AL596247-1|CAI13964.1| 453|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 453
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 66 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 121
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 122 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 180
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 181 KNLINQMLTINPAK-RITADQALKHPWV 207
>AF415197-1|AAM33514.1| 566|Homo sapiens
calcium/calmodulin-dependent protein kinase II gamma
protein.
Length = 566
Score = 73.7 bits (173), Expect = 8e-13
Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)
Frame = -1
Query: 541 ETTHRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEIL 371
+ HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L
Sbjct: 109 DIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFG----FAGTPGYLSPEVL 164
Query: 370 KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAEC 200
+ PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E
Sbjct: 165 RKDPYG-KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEA 223
Query: 199 RKLITRILA--PLKMRVKIPQILADPWL 122
+ LI ++L P K R+ Q L PW+
Sbjct: 224 KNLINQMLTINPAK-RITADQALKHPWV 250
>AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 protein.
Length = 1011
Score = 73.7 bits (173), Expect = 8e-13
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMD--HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+L HRDIK +N+L++ GL +K+SDFG + K G+ +ETF G+ Y +
Sbjct: 484 YLHDNHIVHRDIKGDNVLINTFSGL-LKISDFGTS----KRLAGITPCTETFTGTLQYMA 538
Query: 382 PEIL-KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQVQNKVSFPREPKV 212
PEI+ +G + +D+WS+G + + GR PF + Q + + KV P +
Sbjct: 539 PEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSL 598
Query: 211 SAECRKLITRILAP-LKMRVKIPQILADPWLNPNQQSK 101
SAE + + R P ++R +L DP+L P ++S+
Sbjct: 599 SAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSR 636
Score = 30.7 bits (66), Expect = 7.2
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = -1
Query: 727 IGSGSYATVKVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 551
+G G+Y V A DRH ++AIK I + + + L EI + + L+H+N++R+L
Sbjct: 377 LGKGTYGVV-YAGRDRHTRVRIAIKEIPERDSR---FSQPLHEEIALHRRLRHKNIVRYL 432
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 73.7 bits (173), Expect = 8e-13
Identities = 47/145 (32%), Positives = 82/145 (56%), Gaps = 3/145 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRDIK ENLL+ +K++DFG++ H +T CG+ Y PE+++G Y
Sbjct: 164 HRDIKPENLLLGFRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY- 216
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D+W +GV+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L
Sbjct: 217 DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLL 274
Query: 175 --APLKMRVKIPQILADPWLNPNQQ 107
PL+ R+ + QIL PW+ + +
Sbjct: 275 RYQPLE-RLPLAQILKHPWVQAHSR 298
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/83 (31%), Positives = 43/83 (51%)
Frame = -1
Query: 775 RKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREI 596
R+LTV + + +GR +G G + V +A + VA+K++ K Q + L+ L REI
Sbjct: 36 RRLTVDD---FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREI 92
Query: 595 EVVKGLKHENLIRFLQAIETTHR 527
E+ L+H N++R R
Sbjct: 93 EIQAHLQHPNILRLYNHFHDARR 115
>AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated protein
kinase kinase kinase 6 variant protein.
Length = 1192
Score = 73.7 bits (173), Expect = 8e-13
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMD--HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+L HRDIK +N+L++ GL +K+SDFG + K G+ +ETF G+ Y +
Sbjct: 665 YLHDNHIVHRDIKGDNVLINTFSGL-LKISDFGTS----KRLAGITPCTETFTGTLQYMA 719
Query: 382 PEIL-KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQVQNKVSFPREPKV 212
PEI+ +G + +D+WS+G + + GR PF + Q + + KV P +
Sbjct: 720 PEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSL 779
Query: 211 SAECRKLITRILAP-LKMRVKIPQILADPWLNPNQQSK 101
SAE + + R P ++R +L DP+L P ++S+
Sbjct: 780 SAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSR 817
Score = 30.7 bits (66), Expect = 7.2
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = -1
Query: 727 IGSGSYATVKVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 551
+G G+Y V A DRH ++AIK I + + + L EI + + L+H+N++R+L
Sbjct: 558 LGKGTYGVV-YAGRDRHTRVRIAIKEIPERDSR---FSQPLHEEIALHRRLRHKNIVRYL 613
>AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regulating
kinase 2 protein.
Length = 1288
Score = 73.7 bits (173), Expect = 8e-13
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Frame = -1
Query: 556 FLQAIETTHRDIKCENLLMD--HGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
+L HRDIK +N+L++ GL +K+SDFG + K G+ +ETF G+ Y +
Sbjct: 761 YLHDNHIVHRDIKGDNVLINTFSGL-LKISDFGTS----KRLAGITPCTETFTGTLQYMA 815
Query: 382 PEIL-KGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQ--LLKQVQNKVSFPREPKV 212
PEI+ +G + +D+WS+G + + GR PF + Q + + KV P +
Sbjct: 816 PEIIDQGPRGYGKAADIWSLGCTVIEMATGRPPFHELGSPQAAMFQVGMYKVHPPMPSSL 875
Query: 211 SAECRKLITRILAP-LKMRVKIPQILADPWLNPNQQSK 101
SAE + + R P ++R +L DP+L P ++S+
Sbjct: 876 SAEAQAFLLRTFEPDPRLRASAQTLLGDPFLQPGKRSR 913
Score = 30.7 bits (66), Expect = 7.2
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = -1
Query: 727 IGSGSYATVKVASSDRHN-CQVAIKIISKFQAPGDYLKKFLPREIEVVKGLKHENLIRFL 551
+G G+Y V A DRH ++AIK I + + + L EI + + L+H+N++R+L
Sbjct: 654 LGKGTYGVV-YAGRDRHTRVRIAIKEIPERDSR---FSQPLHEEIALHRRLRHKNIVRYL 709
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 73.7 bits (173), Expect = 8e-13
Identities = 47/145 (32%), Positives = 82/145 (56%), Gaps = 3/145 (2%)
Frame = -1
Query: 532 HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGVPYR 353
HRDIK ENLL+ +K++DFG++ H +T CG+ Y PE+++G Y
Sbjct: 164 HRDIKPENLLLGFRGEVKIADFGWS-VHTPSLR-----RKTMCGTLDYLPPEMIEGRTY- 216
Query: 352 PQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQV-QNKVSFPREPKVSAECRKLITRIL 176
+ D+W +GV+ Y ++ G PF+ ++++ +++ + V FP + A R LI+R+L
Sbjct: 217 DEKVDLWCIGVLCYELLVGYPPFESASHSETYRRILKVDVRFPLSMPLGA--RDLISRLL 274
Query: 175 --APLKMRVKIPQILADPWLNPNQQ 107
PL+ R+ + QIL PW+ + +
Sbjct: 275 RYQPLE-RLPLAQILKHPWVQAHSR 298
Score = 44.4 bits (100), Expect = 5e-04
Identities = 26/83 (31%), Positives = 43/83 (51%)
Frame = -1
Query: 775 RKLTVLESHGYMLGRTIGSGSYATVKVASSDRHNCQVAIKIISKFQAPGDYLKKFLPREI 596
R+LTV + + +GR +G G + V +A + VA+K++ K Q + L+ L REI
Sbjct: 36 RRLTVDD---FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREI 92
Query: 595 EVVKGLKHENLIRFLQAIETTHR 527
E+ L+H N++R R
Sbjct: 93 EIQAHLQHPNILRLYNYFHDARR 115
>L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 73.3 bits (172), Expect = 1e-12
Identities = 39/129 (30%), Positives = 77/129 (59%), Gaps = 1/129 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
++FL + +RD+K +N+L+D +IK++DFG + ++ + + + TFCG+ Y +
Sbjct: 461 LQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGE----SRASTFCGTPDYIA 516
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK-VSA 206
PEIL+G+ Y D WS GV+LY ++ G+ PF + +L + + +V P P+ ++
Sbjct: 517 PEILQGLKY-TFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESI--RVDTPHYPRWITK 573
Query: 205 ECRKLITRI 179
E + ++ ++
Sbjct: 574 ESKDILEKL 582
>L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 73.3 bits (172), Expect = 1e-12
Identities = 39/129 (30%), Positives = 77/129 (59%), Gaps = 1/129 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
++FL + +RD+K +N+L+D +IK++DFG + ++ + + + TFCG+ Y +
Sbjct: 461 LQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGE----SRASTFCGTPDYIA 516
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK-VSA 206
PEIL+G+ Y D WS GV+LY ++ G+ PF + +L + + +V P P+ ++
Sbjct: 517 PEILQGLKY-TFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESI--RVDTPHYPRWITK 573
Query: 205 ECRKLITRI 179
E + ++ ++
Sbjct: 574 ESKDILEKL 582
>D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-type
protein.
Length = 626
Score = 73.3 bits (172), Expect = 1e-12
Identities = 39/129 (30%), Positives = 77/129 (59%), Gaps = 1/129 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
++FL + +RD+K +N+L+D +IK++DFG + ++ + + + TFCG+ Y +
Sbjct: 411 LQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGE----SRASTFCGTPDYIA 466
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK-VSA 206
PEIL+G+ Y D WS GV+LY ++ G+ PF + +L + + +V P P+ ++
Sbjct: 467 PEILQGLKY-TFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESI--RVDTPHYPRWITK 523
Query: 205 ECRKLITRI 179
E + ++ ++
Sbjct: 524 ESKDILEKL 532
>BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta
protein.
Length = 676
Score = 73.3 bits (172), Expect = 1e-12
Identities = 39/129 (30%), Positives = 77/129 (59%), Gaps = 1/129 (0%)
Frame = -1
Query: 562 IRFLQAIETTHRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYAS 383
++FL + +RD+K +N+L+D +IK++DFG + ++ + + + TFCG+ Y +
Sbjct: 461 LQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGE----SRASTFCGTPDYIA 516
Query: 382 PEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQNKVSFPREPK-VSA 206
PEIL+G+ Y D WS GV+LY ++ G+ PF + +L + + +V P P+ ++
Sbjct: 517 PEILQGLKY-TFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESI--RVDTPHYPRWITK 573
Query: 205 ECRKLITRI 179
E + ++ ++
Sbjct: 574 ESKDILEKL 582
>BC040457-1|AAH40457.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II alpha protein.
Length = 478
Score = 72.5 bits (170), Expect = 2e-12
Identities = 51/146 (34%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Frame = -1
Query: 532 HRDIKCENLLMDH---GLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGV 362
HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L+
Sbjct: 133 HRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFG----FAGTPGYLSPEVLRKD 188
Query: 361 PYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKL 191
PY + D+W+ GV+LY ++ G PF D + +L KQ++ FP V+ E + L
Sbjct: 189 PYG-KPVDLWACGVILYILLVGYPPFWDEDQHRLYKQIKAGAYDFPSPEWDTVTPEAKDL 247
Query: 190 ITRILA--PLKMRVKIPQILADPWLN 119
I ++L P K R+ + L PW++
Sbjct: 248 INKMLTINPSK-RITAAEALKHPWIS 272
>BC032784-1|AAH32784.1| 478|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II delta protein.
Length = 478
Score = 72.5 bits (170), Expect = 2e-12
Identities = 50/145 (34%), Positives = 76/145 (52%), Gaps = 8/145 (5%)
Frame = -1
Query: 532 HRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGV 362
HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L+
Sbjct: 134 HRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKD 189
Query: 361 PYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKL 191
PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + L
Sbjct: 190 PYG-KPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 248
Query: 190 ITRILA--PLKMRVKIPQILADPWL 122
I ++L P K R+ + L PW+
Sbjct: 249 INKMLTINPAK-RITASEALKHPWI 272
>BC022558-1|AAH22558.1| 344|Homo sapiens CAMK2D protein protein.
Length = 344
Score = 72.5 bits (170), Expect = 2e-12
Identities = 50/145 (34%), Positives = 76/145 (52%), Gaps = 8/145 (5%)
Frame = -1
Query: 532 HRDIKCENLLM---DHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSYAYASPEILKGV 362
HRD+K ENLL+ G +KL+DFG A + F F G+ Y SPE+L+
Sbjct: 134 HRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFG----FAGTPGYLSPEVLRKD 189
Query: 361 PYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPRE--PKVSAECRKL 191
PY + D+W+ GV+LY ++ G PF D + +L +Q++ FP V+ E + L
Sbjct: 190 PYG-KPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDL 248
Query: 190 ITRILA--PLKMRVKIPQILADPWL 122
I ++L P K R+ + L PW+
Sbjct: 249 INKMLTINPAK-RITASEALKHPWI 272
>AK075048-1|BAC11371.1| 434|Homo sapiens protein ( Homo sapiens
cDNA FLJ90567 fis, clone OVARC1001569, weakly similar to
PROBABLE SERINE/THREONINE-PROTEIN KINASE YKL101W (EC
2.7.1.-). ).
Length = 434
Score = 72.5 bits (170), Expect = 2e-12
Identities = 40/134 (29%), Positives = 78/134 (58%), Gaps = 3/134 (2%)
Frame = -1
Query: 568 NLIRFLQAIETT--HRDIKCENLLMDHGLNIKLSDFGFARGHMKPKNGVFALSETFCGSY 395
+++R ++A+ HRD+K N++++ + +++ F G G + GS
Sbjct: 180 DVVRVVEALHQNIVHRDLKLGNMVLNKRTH-RITITNFCLGKHLVSEGDLLKDQR--GSP 236
Query: 394 AYASPEILKGVPYRPQDSDVWSMGVVLYAIVYGRLPFDDTNYTQLLKQVQ-NKVSFPREP 218
AY SP++L G PYR + SD+W++GVVL+ ++YG+ PF D+ +L ++++ + + P +
Sbjct: 237 AYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDG 296
Query: 217 KVSAECRKLITRIL 176
+VS LI ++L
Sbjct: 297 RVSENTVCLIRKLL 310
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 128,581,203
Number of Sequences: 237096
Number of extensions: 2847756
Number of successful extensions: 12408
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 8232
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9907
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 11039988564
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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