Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmte10h07
(809 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein. 159 1e-38
AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein. 159 1e-38
BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein. 148 3e-35
AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens ... 148 3e-35
AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein. 148 3e-35
AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1 pro... 148 3e-35
AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein. 148 3e-35
X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein. 146 1e-34
BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis, ... 146 1e-34
AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis, ... 146 1e-34
AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis, ... 146 1e-34
X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for ... 132 1e-30
BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein. 132 1e-30
AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein. 132 1e-30
M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protei... 131 3e-30
BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin ... 131 3e-30
BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin ... 131 3e-30
AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein. 131 3e-30
AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis, ... 95 2e-19
AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis, ... 95 2e-19
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 91 3e-18
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 91 3e-18
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 91 3e-18
D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein. 79 2e-14
BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein. 79 2e-14
BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin (am... 66 1e-10
AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis, ... 66 1e-10
AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens ... 66 1e-10
BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein. 65 3e-10
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 62 2e-09
AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein. 60 9e-09
AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein. 60 9e-09
AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein. 60 9e-09
AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein. 60 9e-09
AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein. 60 9e-09
AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein. 60 9e-09
AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein. 60 9e-09
AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis, ... 59 2e-08
AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens ... 55 3e-07
U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein. 55 3e-07
AB209574-1|BAD92811.1| 326|Homo sapiens villin-like variant pro... 40 0.008
U27381-1|AAA96010.1| 1447|Homo sapiens protein ( Human Menkes di... 33 1.6
AL645821-1|CAI42806.1| 1500|Homo sapiens ATPase, Cu++ transporti... 33 1.6
Z94801-1|CAB08162.2| 1376|Homo sapiens Menkes Disease (ATP7A) pr... 32 2.1
X82336-1|CAB94714.1| 1500|Homo sapiens Menkes disease protein. 31 3.7
L06133-1|AAA35580.1| 1500|Homo sapiens Cu++-transporting P-type ... 31 3.7
DQ012935-1|AAY22174.1| 1503|Homo sapiens transient receptor pote... 31 3.7
BC112342-1|AAI12343.1| 1553|Homo sapiens TRPM2 protein protein. 31 3.7
AY603182-1|AAT12288.1| 846|Homo sapiens TRPM2-S protein. 31 3.7
AP001754-4|BAA95563.1| 1503|Homo sapiens transient receptor pote... 31 3.7
AJ878416-1|CAI47593.1| 1503|Homo sapiens transient receptor pote... 31 3.7
AJ417076-1|CAD01139.1| 1449|Homo sapiens putative TRP cation cha... 31 3.7
AB166746-1|BAD83706.1| 1289|Homo sapiens transient receptor pote... 31 3.7
AB166745-1|BAD83705.1| 1503|Homo sapiens transient receptor pote... 31 3.7
AB001535-1|BAA34700.1| 1503|Homo sapiens KNP3 protein. 31 3.7
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 30 8.6
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 30 8.6
BC129991-1|AAI29992.1| 754|Homo sapiens PERQ1 protein protein. 30 8.6
BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3, precu... 30 8.6
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 30 8.6
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 30 8.6
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 30 8.6
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 30 8.6
AK128318-1|BAC87382.1| 421|Homo sapiens protein ( Homo sapiens ... 30 8.6
AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens ... 30 8.6
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 30 8.6
>BC111730-1|AAI11731.1| 812|Homo sapiens AVIL protein protein.
Length = 812
Score = 159 bits (385), Expect = 1e-38
Identities = 93/250 (37%), Positives = 138/250 (55%), Gaps = 6/250 (2%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F YF+ + Y +GG SG HV TN KR+ VKGKR++R +V+ S N+GDVF
Sbjct: 97 FRGYFKQGIIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVF 156
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIV--DKYSSDVDVQKFF 456
+LDL I + G ++ + E+LKA+ A +RD++ GR + ++ DK ++ ++ K
Sbjct: 157 LLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVL 216
Query: 455 -TALG--SGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQEN 288
LG S +K VPDE ++ + S ++L +SD+ G++ VT + ++P Q+
Sbjct: 217 QDTLGRRSIIKPTVPDEI-------IDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDL 269
Query: 287 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEP 108
L+ + YILD IYVW GK AT EK AM+KA + K+YPS V V E
Sbjct: 270 LNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAES 329
Query: 107 AAFKQYFFTW 78
A FKQ F W
Sbjct: 330 AMFKQLFQKW 339
Score = 65.3 bits (152), Expect = 2e-10
Identities = 65/250 (26%), Positives = 112/250 (44%), Gaps = 6/250 (2%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGD 636
F + F+ L EGG N R+FQ+ G K + + +V +S+N D
Sbjct: 478 FMAIFKGKLVIFEGGTSRKGN---AEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 534
Query: 635 VFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFF 456
VF+L + Y++ G+ + E+ A A+ + D G + V + + +F+
Sbjct: 535 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCD------GSENTV---AEGQEPAEFW 585
Query: 455 TALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQ 276
LG G D+ + + + L E S+ TG+ VT ++ F Q++L+P
Sbjct: 586 DLLG-GKTPYANDKRLQQEILDVQSR------LFECSNKTGQFVVTEITD-FTQDDLNPT 637
Query: 275 NAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEP 108
+ +LDT +++WIG +A A EK A+ AQ+ L+ +PS + + Q EP
Sbjct: 638 DVMLLDTWD-QVFLWIGAEANATEKESALATAQQYLH--THPSGRDPDTPILIIKQGFEP 694
Query: 107 AAFKQYFFTW 78
F +F W
Sbjct: 695 PIFTGWFLAW 704
>AF041449-1|AAC25051.1| 819|Homo sapiens advillin protein.
Length = 819
Score = 159 bits (385), Expect = 1e-38
Identities = 93/250 (37%), Positives = 138/250 (55%), Gaps = 6/250 (2%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F YF+ + Y +GG SG HV TN KR+ VKGKR++R +V+ S N+GDVF
Sbjct: 104 FRGYFKQGIIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVF 163
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIV--DKYSSDVDVQKFF 456
+LDL I + G ++ + E+LKA+ A +RD++ GR + ++ DK ++ ++ K
Sbjct: 164 LLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVL 223
Query: 455 -TALG--SGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQEN 288
LG S +K VPDE ++ + S ++L +SD+ G++ VT + ++P Q+
Sbjct: 224 QDTLGRRSIIKPTVPDEI-------IDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDL 276
Query: 287 LSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEP 108
L+ + YILD IYVW GK AT EK AM+KA + K+YPS V V E
Sbjct: 277 LNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAES 336
Query: 107 AAFKQYFFTW 78
A FKQ F W
Sbjct: 337 AMFKQLFQKW 346
Score = 65.3 bits (152), Expect = 2e-10
Identities = 65/250 (26%), Positives = 112/250 (44%), Gaps = 6/250 (2%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGD 636
F + F+ L EGG N R+FQ+ G K + + +V +S+N D
Sbjct: 485 FMAIFKGKLVIFEGGTSRKGN---AEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541
Query: 635 VFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFF 456
VF+L + Y++ G+ + E+ A A+ + D G + V + + +F+
Sbjct: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCD------GSENTV---AEGQEPAEFW 592
Query: 455 TALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQ 276
LG G D+ + + + L E S+ TG+ VT ++ F Q++L+P
Sbjct: 593 DLLG-GKTPYANDKRLQQEILDVQSR------LFECSNKTGQFVVTEITD-FTQDDLNPT 644
Query: 275 NAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEP 108
+ +LDT +++WIG +A A EK A+ AQ+ L+ +PS + + Q EP
Sbjct: 645 DVMLLDTWD-QVFLWIGAEANATEKESALATAQQYLH--THPSGRDPDTPILIIKQGFEP 701
Query: 107 AAFKQYFFTW 78
F +F W
Sbjct: 702 PIFTGWFLAW 711
>BC021090-1|AAH21090.1| 715|Homo sapiens SCIN protein protein.
Length = 715
Score = 148 bits (358), Expect = 3e-35
Identities = 91/251 (36%), Positives = 131/251 (52%), Gaps = 5/251 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F SYF+ L Y GG SG NHV+TN KR+ VKG+R VR +V S NKGD F
Sbjct: 107 FVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCF 166
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
++DL +IY + G E+LKA A +R + GR + +V++ S ++ K
Sbjct: 167 IIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-- 224
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVI--LSEVSDATGKIKVTPLSK--PFKQENLS 282
G K +PD GGDD + + ++ + L VSDA+G ++VT +++ PF L
Sbjct: 225 ---GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLL 278
Query: 281 PQNAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 105
+ +ILD + I+VW GK A E+ AM A+E L NY Q+ + + E
Sbjct: 279 SEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETP 338
Query: 104 AFKQYFFTWRD 72
FKQ+F WRD
Sbjct: 339 IFKQFFKDWRD 349
Score = 55.2 bits (127), Expect = 3e-07
Identities = 54/218 (24%), Positives = 94/218 (43%), Gaps = 5/218 (2%)
Frame = -1
Query: 716 RMFQVKGKRD--VRVRQVDPQIASMNKGDVFVLDL-DNDIYVFVGEKAKNVEKLKAISFA 546
R+FQV+ R+ +VD S+N DVFVL L N Y++VG+ A E+ A A
Sbjct: 511 RLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVA 570
Query: 545 NQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASN 366
+ ++ + + + ++F+ +LG G KD ++
Sbjct: 571 SVLKCKTL----------RIQEGEEPEEFWNSLG-GKKDYQTSPLLETQAEDHPPR---- 615
Query: 365 VILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMT 186
L S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++
Sbjct: 616 --LYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLK 672
Query: 185 KAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 78
A+ L + + + Q EP F +F W
Sbjct: 673 SAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 710
>AK075123-1|BAC11416.1| 715|Homo sapiens protein ( Homo sapiens
cDNA FLJ90642 fis, clone PLACE1004078, highly similar to
Bovine mRNA for adseverin. ).
Length = 715
Score = 148 bits (358), Expect = 3e-35
Identities = 91/251 (36%), Positives = 131/251 (52%), Gaps = 5/251 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F SYF+ L Y GG SG NHV+TN KR+ VKG+R VR +V S NKGD F
Sbjct: 107 FVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCF 166
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
++DL +IY + G E+LKA A +R + GR + +V++ S ++ K
Sbjct: 167 IIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-- 224
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVI--LSEVSDATGKIKVTPLSK--PFKQENLS 282
G K +PD GGDD + + ++ + L VSDA+G ++VT +++ PF L
Sbjct: 225 ---GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLL 278
Query: 281 PQNAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 105
+ +ILD + I+VW GK A E+ AM A+E L NY Q+ + + E
Sbjct: 279 SEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETP 338
Query: 104 AFKQYFFTWRD 72
FKQ+F WRD
Sbjct: 339 IFKQFFKDWRD 349
Score = 55.2 bits (127), Expect = 3e-07
Identities = 54/218 (24%), Positives = 94/218 (43%), Gaps = 5/218 (2%)
Frame = -1
Query: 716 RMFQVKGKRD--VRVRQVDPQIASMNKGDVFVLDL-DNDIYVFVGEKAKNVEKLKAISFA 546
R+FQV+ R+ +VD S+N DVFVL L N Y++VG+ A E+ A A
Sbjct: 511 RLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVA 570
Query: 545 NQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASN 366
+ ++ + + + ++F+ +LG G KD ++
Sbjct: 571 SVLKCKTL----------RIQEGEEPEEFWNSLG-GKKDYQTSPLLETQAEDHPPR---- 615
Query: 365 VILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMT 186
L S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++
Sbjct: 616 --LYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLK 672
Query: 185 KAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 78
A+ L + + + Q EP F +F W
Sbjct: 673 SAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 710
>AF276507-1|AAK60494.1| 715|Homo sapiens scinderin protein.
Length = 715
Score = 148 bits (358), Expect = 3e-35
Identities = 91/251 (36%), Positives = 131/251 (52%), Gaps = 5/251 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F SYF+ L Y GG SG NHV+TN KR+ VKG+R VR +V S NKGD F
Sbjct: 107 FVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCF 166
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
++DL +IY + G E+LKA A +R + GR + +V++ S ++ K
Sbjct: 167 IIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-- 224
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVI--LSEVSDATGKIKVTPLSK--PFKQENLS 282
G K +PD GGDD + + ++ + L VSDA+G ++VT +++ PF L
Sbjct: 225 ---GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLL 278
Query: 281 PQNAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 105
+ +ILD + I+VW GK A E+ AM A+E L NY Q+ + + E
Sbjct: 279 SEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETP 338
Query: 104 AFKQYFFTWRD 72
FKQ+F WRD
Sbjct: 339 IFKQFFKDWRD 349
Score = 55.2 bits (127), Expect = 3e-07
Identities = 54/218 (24%), Positives = 94/218 (43%), Gaps = 5/218 (2%)
Frame = -1
Query: 716 RMFQVKGKRD--VRVRQVDPQIASMNKGDVFVLDLD-NDIYVFVGEKAKNVEKLKAISFA 546
R+FQV+ R+ +VD S+N DVFVL L N Y++VG+ A E+ A A
Sbjct: 511 RLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLSQNSGYIWVGKGASQEEEKGAEYVA 570
Query: 545 NQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASN 366
+ ++ + + + ++F+ +LG G KD ++
Sbjct: 571 SVLKCKTL----------RIQEGEEPEEFWNSLG-GKKDYQTSPLLETQAEDHPPR---- 615
Query: 365 VILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMT 186
L S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++
Sbjct: 616 --LYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLK 672
Query: 185 KAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 78
A+ L + + + Q EP F +F W
Sbjct: 673 SAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 710
>AC005281-1|AAD15423.1| 527|Homo sapiens WUGSC:H_DJ0722F20.1
protein.
Length = 527
Score = 148 bits (358), Expect = 3e-35
Identities = 91/251 (36%), Positives = 131/251 (52%), Gaps = 5/251 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F SYF+ L Y GG SG NHV+TN KR+ VKG+R VR +V S NKGD F
Sbjct: 107 FVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCF 166
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
++DL +IY + G E+LKA A +R + GR + +V++ S ++ K
Sbjct: 167 IIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-- 224
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVI--LSEVSDATGKIKVTPLSK--PFKQENLS 282
G K +PD GGDD + + ++ + L VSDA+G ++VT +++ PF L
Sbjct: 225 ---GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLL 278
Query: 281 PQNAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 105
+ +ILD + I+VW GK A E+ AM A+E L NY Q+ + + E
Sbjct: 279 SEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETP 338
Query: 104 AFKQYFFTWRD 72
FKQ+F WRD
Sbjct: 339 IFKQFFKDWRD 349
>AB067492-1|BAB67798.1| 626|Homo sapiens KIAA1905 protein protein.
Length = 626
Score = 148 bits (358), Expect = 3e-35
Identities = 91/251 (36%), Positives = 131/251 (52%), Gaps = 5/251 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F SYF+ L Y GG SG NHV+TN KR+ VKG+R VR +V S NKGD F
Sbjct: 153 FVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCF 212
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
++DL +IY + G E+LKA A +R + GR + +V++ S ++ K
Sbjct: 213 IIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVL-- 270
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVI--LSEVSDATGKIKVTPLSK--PFKQENLS 282
G K +PD GGDD + + ++ + L VSDA+G ++VT +++ PF L
Sbjct: 271 ---GEKPELPD---GGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLL 324
Query: 281 PQNAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPA 105
+ +ILD + I+VW GK A E+ AM A+E L NY Q+ + + E
Sbjct: 325 SEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETP 384
Query: 104 AFKQYFFTWRD 72
FKQ+F WRD
Sbjct: 385 IFKQFFKDWRD 395
>X04412-1|CAA28000.1| 782|Homo sapiens plasma gelsolin protein.
Length = 782
Score = 146 bits (353), Expect = 1e-34
Identities = 87/249 (34%), Positives = 128/249 (51%), Gaps = 3/249 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GD F
Sbjct: 157 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 216
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
+LDL N+I+ + G + E+LKA + +RD + GR RV + ++ + +
Sbjct: 217 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE---GTEPEAMLQV 273
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLS--KPFKQENLSPQ 276
LG E T +D R A L +VS+ G + V+ ++ PF Q L +
Sbjct: 274 LGPKPALPAGTEDTAKEDAA-NRKLAK---LYKVSNGAGTMSVSLVADENPFAQGALKSE 329
Query: 275 NAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAF 99
+ +ILD G I+VW GKQA E+ A+ A + + +YP QV+ + + E F
Sbjct: 330 DCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLF 389
Query: 98 KQYFFTWRD 72
KQ+F WRD
Sbjct: 390 KQFFKNWRD 398
Score = 66.5 bits (155), Expect = 1e-10
Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Frame = -1
Query: 731 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKA 558
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 559 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 618
Query: 557 ISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 378
+R Q V + + D F+ ALG S D++ + +
Sbjct: 619 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 665
Query: 377 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 198
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 666 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 721
Query: 197 QAMTKAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 72
+A+T A+ + + N +T V Q EP +F +F W D
Sbjct: 722 EALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 765
>BC026033-1|AAH26033.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 146 bits (353), Expect = 1e-34
Identities = 87/249 (34%), Positives = 128/249 (51%), Gaps = 3/249 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GD F
Sbjct: 157 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 216
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
+LDL N+I+ + G + E+LKA + +RD + GR RV + ++ + +
Sbjct: 217 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE---GTEPEAMLQV 273
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLS--KPFKQENLSPQ 276
LG E T +D R A L +VS+ G + V+ ++ PF Q L +
Sbjct: 274 LGPKPALPAGTEDTAKEDAA-NRKLAK---LYKVSNGAGTMSVSLVADENPFAQGALKSE 329
Query: 275 NAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAF 99
+ +ILD G I+VW GKQA E+ A+ A + + +YP QV+ + + E F
Sbjct: 330 DCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLF 389
Query: 98 KQYFFTWRD 72
KQ+F WRD
Sbjct: 390 KQFFKNWRD 398
Score = 66.5 bits (155), Expect = 1e-10
Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Frame = -1
Query: 731 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKA 558
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 559 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 618
Query: 557 ISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 378
+R Q V + + D F+ ALG S D++ + +
Sbjct: 619 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 665
Query: 377 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 198
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 666 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 721
Query: 197 QAMTKAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 72
+A+T A+ + + N +T V Q EP +F +F W D
Sbjct: 722 EALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 765
>AL513122-6|CAM20459.1| 731|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 731
Score = 146 bits (353), Expect = 1e-34
Identities = 87/249 (34%), Positives = 128/249 (51%), Gaps = 3/249 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GD F
Sbjct: 106 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 165
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
+LDL N+I+ + G + E+LKA + +RD + GR RV + ++ + +
Sbjct: 166 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE---GTEPEAMLQV 222
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLS--KPFKQENLSPQ 276
LG E T +D R A L +VS+ G + V+ ++ PF Q L +
Sbjct: 223 LGPKPALPAGTEDTAKEDAA-NRKLAK---LYKVSNGAGTMSVSLVADENPFAQGALKSE 278
Query: 275 NAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAF 99
+ +ILD G I+VW GKQA E+ A+ A + + +YP QV+ + + E F
Sbjct: 279 DCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLF 338
Query: 98 KQYFFTWRD 72
KQ+F WRD
Sbjct: 339 KQFFKNWRD 347
Score = 66.5 bits (155), Expect = 1e-10
Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Frame = -1
Query: 731 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKA 558
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 508 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 567
Query: 557 ISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 378
+R Q V + + D F+ ALG S D++ + +
Sbjct: 568 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 614
Query: 377 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 198
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 615 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 670
Query: 197 QAMTKAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 72
+A+T A+ + + N +T V Q EP +F +F W D
Sbjct: 671 EALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 714
>AL513122-3|CAI14413.1| 782|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 782
Score = 146 bits (353), Expect = 1e-34
Identities = 87/249 (34%), Positives = 128/249 (51%), Gaps = 3/249 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GD F
Sbjct: 157 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 216
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
+LDL N+I+ + G + E+LKA + +RD + GR RV + ++ + +
Sbjct: 217 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE---GTEPEAMLQV 273
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLS--KPFKQENLSPQ 276
LG E T +D R A L +VS+ G + V+ ++ PF Q L +
Sbjct: 274 LGPKPALPAGTEDTAKEDAA-NRKLAK---LYKVSNGAGTMSVSLVADENPFAQGALKSE 329
Query: 275 NAYILD-TISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAF 99
+ +ILD G I+VW GKQA E+ A+ A + + +YP QV+ + + E F
Sbjct: 330 DCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLF 389
Query: 98 KQYFFTWRD 72
KQ+F WRD
Sbjct: 390 KQFFKNWRD 398
Score = 66.5 bits (155), Expect = 1e-10
Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Frame = -1
Query: 731 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKA 558
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 559 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 618
Query: 557 ISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 378
+R Q V + + D F+ ALG S D++ + +
Sbjct: 619 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 665
Query: 377 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 198
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 666 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 721
Query: 197 QAMTKAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 72
+A+T A+ + + N +T V Q EP +F +F W D
Sbjct: 722 EALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 765
>X12901-1|CAA31386.1| 827|Homo sapiens protein ( Human mRNA for
villin. ).
Length = 827
Score = 132 bits (319), Expect = 1e-30
Identities = 84/245 (34%), Positives = 126/245 (51%), Gaps = 1/245 (0%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F YF+ L +GG SG HV TN+ +R+ VKGKR+V +V+ S N+GDVF
Sbjct: 107 FRGYFKQGLVIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVF 166
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
+LDL I + G ++ +E+L+ ++ A ++RDQ+ GR V +VD +++ K
Sbjct: 167 LLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDG-ENELASPKLMEV 225
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQENLSPQN 273
+ + V + D E + + L VSD+ G + V + ++P Q+ LS ++
Sbjct: 226 M-NHVLGKRRELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHED 284
Query: 272 AYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQ 93
YILD IYVW GK+A EK AM+ A + AK YP QV E A F+Q
Sbjct: 285 CYILDQGGLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQ 344
Query: 92 YFFTW 78
F W
Sbjct: 345 LFQKW 349
Score = 71.3 bits (167), Expect = 4e-12
Identities = 74/266 (27%), Positives = 118/266 (44%), Gaps = 6/266 (2%)
Frame = -1
Query: 803 SYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGK--RDVRVRQVDPQIASMNKGDVF 630
S F+ + +GG S N++ T G R+FQV+G + + +V + +N DVF
Sbjct: 490 SIFKGRMVVYQGGT-SRTNNLET--GPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVF 546
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
VL + Y++ G+ E+ A V D +V + + ++ F+ A
Sbjct: 547 VLKTQSCCYLWCGKGCSGDER----EMAKMVADTISRTEKQVVVEGQEPAN-----FWMA 597
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNA 270
LG P +T +E N L E S+ TG+ T + F Q++L +
Sbjct: 598 LGGKA----PYANTKRLQEE---NLVITPRLFECSNKTGRFLATEIPD-FNQDDLEEDDV 649
Query: 269 YILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEPAA 102
++LD + ++ WIGK A EK A T AQE L K +PS + V Q EP
Sbjct: 650 FLLD-VWDQVFFWIGKHANEEEKKAAATTAQEYL--KTHPSGRDPETPIIVVKQGHEPPT 706
Query: 101 FKQYFFTWRDFGMSHSRVI*KLKAQN 24
F +F W F S+++ LKA++
Sbjct: 707 FTGWFLAWDPFKWSNTKSYEDLKAES 732
>BC017303-1|AAH17303.1| 421|Homo sapiens VIL1 protein protein.
Length = 421
Score = 132 bits (319), Expect = 1e-30
Identities = 84/245 (34%), Positives = 126/245 (51%), Gaps = 1/245 (0%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F YF+ L +GG SG HV TN+ +R+ VKGKR+V +V+ S N+GDVF
Sbjct: 107 FRGYFKQGLVIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVF 166
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
+LDL I + G ++ +E+L+ ++ A ++RDQ+ GR V +VD +++ K
Sbjct: 167 LLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDG-ENELASPKLMEV 225
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQENLSPQN 273
+ + V + D E + + L VSD+ G + V + ++P Q+ LS ++
Sbjct: 226 M-NHVLGKRRELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHED 284
Query: 272 AYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQ 93
YILD IYVW GK+A EK AM+ A + AK YP QV E A F+Q
Sbjct: 285 CYILDQGGLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQ 344
Query: 92 YFFTW 78
F W
Sbjct: 345 LFQKW 349
>AK223398-1|BAD97118.1| 827|Homo sapiens villin 1 variant protein.
Length = 827
Score = 132 bits (319), Expect = 1e-30
Identities = 84/245 (34%), Positives = 126/245 (51%), Gaps = 1/245 (0%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F YF+ L +GG SG HV TN+ +R+ VKGKR+V +V+ S N+GDVF
Sbjct: 107 FRGYFKQGLVIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVF 166
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
+LDL I + G ++ +E+L+ ++ A ++RDQ+ GR V +VD +++ K
Sbjct: 167 LLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDG-ENELASPKLMEV 225
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL-SKPFKQENLSPQN 273
+ + V + D E + + L VSD+ G + V + ++P Q+ LS ++
Sbjct: 226 M-NHVLGKRRELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHED 284
Query: 272 AYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQ 93
YILD IYVW GK+A EK AM+ A + AK YP QV E A F+Q
Sbjct: 285 CYILDQGGLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQ 344
Query: 92 YFFTW 78
F W
Sbjct: 345 LFQKW 349
Score = 70.9 bits (166), Expect = 5e-12
Identities = 74/265 (27%), Positives = 117/265 (44%), Gaps = 6/265 (2%)
Frame = -1
Query: 803 SYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGK--RDVRVRQVDPQIASMNKGDVF 630
S F+ + +GG S N++ T G R+FQV+G + + +V + +N DVF
Sbjct: 490 SIFKGRMVVYQGGT-SRTNNLET--GPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVF 546
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
VL + Y++ G+ E+ A V D +V + + ++ F+ A
Sbjct: 547 VLKTQSCCYLWCGKGCSGDER----EMAKMVADTISRTEKQVVVEGQEPAN-----FWMA 597
Query: 449 LGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNA 270
LG P +T +E N L E S+ TG+ T + F Q++L +
Sbjct: 598 LGGKA----PYANTKRLQEE---NLVITPRLFECSNKTGRFLATEIPD-FNQDDLEEDDV 649
Query: 269 YILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEPAA 102
++LD + ++ WIGK A EK A T AQE L K +PS + V Q EP
Sbjct: 650 FLLD-VWDQVFFWIGKHANEEEKKAAATTAQEYL--KTHPSGRDPETPIIVVKQGHEPPT 706
Query: 101 FKQYFFTWRDFGMSHSRVI*KLKAQ 27
F +F W F S+++ LKA+
Sbjct: 707 FTGWFLAWDPFKWSNTKSYEDLKAE 731
>M94345-1|AAA59570.1| 348|Homo sapiens macrophage capping protein
protein.
Length = 348
Score = 131 bits (317), Expect = 3e-30
Identities = 81/249 (32%), Positives = 128/249 (51%), Gaps = 4/249 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQ-KRMFQVKGKRDVRVRQVDPQIASMNKGDV 633
F SYF L Y EGG S F+ T A A K+++QVKGK+++R + S N GD
Sbjct: 106 FMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDC 165
Query: 632 FVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFT 453
F+LDL +I+ + G K+ +E+ KA A +RD + G+ +V+IV ++ +
Sbjct: 166 FILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL- 224
Query: 452 ALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENLSP 279
G K + E +D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 225 ----GPKPAL-KEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLIS 279
Query: 278 QNAYILDT-ISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAA 102
+ ++LD + G IY+W G++A E+ A+ A+ ++ Y QV + Q E
Sbjct: 280 DDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPI 339
Query: 101 FKQYFFTWR 75
FKQ+F W+
Sbjct: 340 FKQFFKDWK 348
>BC014549-1|AAH14549.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 131 bits (317), Expect = 3e-30
Identities = 81/249 (32%), Positives = 128/249 (51%), Gaps = 4/249 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQ-KRMFQVKGKRDVRVRQVDPQIASMNKGDV 633
F SYF L Y EGG S F+ T A A K+++QVKGK+++R + S N GD
Sbjct: 106 FMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDC 165
Query: 632 FVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFT 453
F+LDL +I+ + G K+ +E+ KA A +RD + G+ +V+IV ++ +
Sbjct: 166 FILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL- 224
Query: 452 ALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENLSP 279
G K + E +D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 225 ----GPKPAL-KEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLIS 279
Query: 278 QNAYILDT-ISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAA 102
+ ++LD + G IY+W G++A E+ A+ A+ ++ Y QV + Q E
Sbjct: 280 DDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPI 339
Query: 101 FKQYFFTWR 75
FKQ+F W+
Sbjct: 340 FKQFFKDWK 348
>BC000728-1|AAH00728.1| 348|Homo sapiens capping protein (actin
filament), gelsolin-like protein.
Length = 348
Score = 131 bits (317), Expect = 3e-30
Identities = 81/249 (32%), Positives = 128/249 (51%), Gaps = 4/249 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQ-KRMFQVKGKRDVRVRQVDPQIASMNKGDV 633
F SYF L Y EGG S F+ T A A K+++QVKGK+++R + S N GD
Sbjct: 106 FMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDC 165
Query: 632 FVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFT 453
F+LDL +I+ + G K+ +E+ KA A +RD + G+ +V+IV ++ +
Sbjct: 166 FILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL- 224
Query: 452 ALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENLSP 279
G K + E +D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 225 ----GPKPAL-KEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLIS 279
Query: 278 QNAYILDT-ISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAA 102
+ ++LD + G IY+W G++A E+ A+ A+ ++ Y QV + Q E
Sbjct: 280 DDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGRESPI 339
Query: 101 FKQYFFTWR 75
FKQ+F W+
Sbjct: 340 FKQFFKDWK 348
>AC062037-3|AAY24128.1| 348|Homo sapiens unknown protein.
Length = 348
Score = 131 bits (316), Expect = 3e-30
Identities = 81/249 (32%), Positives = 128/249 (51%), Gaps = 4/249 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQ-KRMFQVKGKRDVRVRQVDPQIASMNKGDV 633
F SYF L Y EGG S F+ T A A K+++QVKGK+++R + S N GD
Sbjct: 106 FMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDC 165
Query: 632 FVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFT 453
F+LDL +I+ + G K+ +E+ KA A +RD + G+ +V+IV ++ +
Sbjct: 166 FILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVL- 224
Query: 452 ALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPL--SKPFKQENLSP 279
G K + E +D ++ A L +VSDATG++ +T + S PF E L
Sbjct: 225 ----GPKPAL-KEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLIS 279
Query: 278 QNAYILDT-ISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAA 102
+ ++LD + G IY+W G++A E+ A+ A+ ++ Y QV + Q E
Sbjct: 280 DDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPI 339
Query: 101 FKQYFFTWR 75
FKQ+F W+
Sbjct: 340 FKQFFKDWK 348
>AL513122-5|CAI14415.1| 260|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 260
Score = 95.5 bits (227), Expect = 2e-19
Identities = 45/107 (42%), Positives = 64/107 (59%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GD F
Sbjct: 106 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 165
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDK 489
+LDL N+I+ + G + E+LKA + +RD + GR RV + ++
Sbjct: 166 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE 212
>AL513122-4|CAI14414.1| 228|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 228
Score = 95.5 bits (227), Expect = 2e-19
Identities = 45/107 (42%), Positives = 64/107 (59%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F YF++ L Y +GG SGF HVV N +R+FQVKG+R VR +V S N GD F
Sbjct: 117 FLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCF 176
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDK 489
+LDL N+I+ + G + E+LKA + +RD + GR RV + ++
Sbjct: 177 ILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEE 223
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 91.5 bits (217), Expect = 3e-18
Identities = 69/257 (26%), Positives = 123/257 (47%), Gaps = 11/257 (4%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ VF
Sbjct: 590 FLQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVF 648
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
+LD DIYV+ G +A KA FA ++ + G+ + ++ ++ +F+ A
Sbjct: 649 LLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEA 705
Query: 449 LG---SGVKDLVPDESTGGDDQEFE--------RNEASNVILSEVSDATGKIKVTPLSKP 303
LG S +K VP++ + ++ N LS K+++ P +
Sbjct: 706 LGGEPSEIKKHVPEDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKQRPKVELMPRMR- 764
Query: 302 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVL 123
Q L + YILD S ++++W+G+++ ++ A+ QEL + P V+R L
Sbjct: 765 LLQSLLDTRCVYILDCWS-DVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSL 823
Query: 122 QNTEPAAFKQYFFTWRD 72
+ TE FK F W D
Sbjct: 824 EGTEAQVFKAKFKNWDD 840
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog protein.
Length = 1268
Score = 91.5 bits (217), Expect = 3e-18
Identities = 69/257 (26%), Positives = 123/257 (47%), Gaps = 11/257 (4%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ VF
Sbjct: 589 FLQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVF 647
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
+LD DIYV+ G +A KA FA ++ + G+ + ++ ++ +F+ A
Sbjct: 648 LLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEA 704
Query: 449 LG---SGVKDLVPDESTGGDDQEFE--------RNEASNVILSEVSDATGKIKVTPLSKP 303
LG S +K VP++ + ++ N LS K+++ P +
Sbjct: 705 LGGEPSEIKKHVPEDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKQRPKVELMPRMR- 763
Query: 302 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVL 123
Q L + YILD S ++++W+G+++ ++ A+ QEL + P V+R L
Sbjct: 764 LLQSLLDTRCVYILDCWS-DVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSL 822
Query: 122 QNTEPAAFKQYFFTWRD 72
+ TE FK F W D
Sbjct: 823 EGTEAQVFKAKFKNWDD 839
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 91.5 bits (217), Expect = 3e-18
Identities = 69/257 (26%), Positives = 123/257 (47%), Gaps = 11/257 (4%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ VF
Sbjct: 590 FLQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVF 648
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
+LD DIYV+ G +A KA FA ++ + G+ + ++ ++ +F+ A
Sbjct: 649 LLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEA 705
Query: 449 LG---SGVKDLVPDESTGGDDQEFE--------RNEASNVILSEVSDATGKIKVTPLSKP 303
LG S +K VP++ + ++ N LS K+++ P +
Sbjct: 706 LGGEPSEIKKHVPEDFWPPQPKLYKVGLGLGYLELPQINYKLSVEHKQRPKVELMPRMR- 764
Query: 302 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVL 123
Q L + YILD S ++++W+G+++ ++ A+ QEL + P V+R L
Sbjct: 765 LLQSLLDTRCVYILDCWS-DVFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSL 823
Query: 122 QNTEPAAFKQYFFTWRD 72
+ TE FK F W D
Sbjct: 824 EGTEAQVFKAKFKNWDD 840
>D88154-1|BAA21668.1| 686|Homo sapiens villin-like protein protein.
Length = 686
Score = 78.6 bits (185), Expect = 2e-14
Identities = 52/177 (29%), Positives = 85/177 (48%), Gaps = 3/177 (1%)
Frame = -1
Query: 593 GEKAKNVEKLKAISFANQVRDQDHHG-RGRVDIVDKYSSDVDVQKFFTA-LGSGVKDLVP 420
G K EK + ++ +RD++ G R ++ +VD + D+ + A LG V L
Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGCRVGSL-- 64
Query: 419 DESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKP-FKQENLSPQNAYILDTISGN 243
++ + + +NV L V + + V L+ P Q+ L ++ YILD
Sbjct: 65 --RAATPSKDINQLQKANVRLYHVYEKGKDLVVLELATPPLTQDLLQEEDFYILDQGGFK 122
Query: 242 IYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 72
IYVW G+ ++ E+ A ++A + AK YP++ V V E AAFKQ F TW +
Sbjct: 123 IYVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSE 179
Score = 43.2 bits (97), Expect = 0.001
Identities = 54/230 (23%), Positives = 97/230 (42%), Gaps = 6/230 (2%)
Frame = -1
Query: 749 NHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKN 576
+H + + R+FQV+G + R +V + +S+N D+F+L + Y++ G+
Sbjct: 328 HHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNG 387
Query: 575 VEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDD 396
++ A + ++ + + F+ ALG P S
Sbjct: 388 DQREMARVVVTVISRKNE---------ETVLEGQEPPHFWEALGGRA----PYPSNKRLP 434
Query: 395 QEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQA 216
+E + L E S G + + + F QE+L + +LDT I++W+G+
Sbjct: 435 EEVPSFQPR---LFECSSHMGCLVLAEVGF-FSQEDLDKYDIMLLDTWQ-EIFLWLGE-- 487
Query: 215 TANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEPAAFKQYFFTW 78
A+E +A+ QE L K +P+ + V Q EP F +FFTW
Sbjct: 488 AASEWKEAVAWGQEYL--KTHPAGRSPATPIVLVKQGHEPPTFIGWFFTW 535
>BC000243-1|AAH00243.1| 686|Homo sapiens VILL protein protein.
Length = 686
Score = 78.6 bits (185), Expect = 2e-14
Identities = 52/177 (29%), Positives = 85/177 (48%), Gaps = 3/177 (1%)
Frame = -1
Query: 593 GEKAKNVEKLKAISFANQVRDQDHHG-RGRVDIVDKYSSDVDVQKFFTA-LGSGVKDLVP 420
G K EK + ++ +RD++ G R ++ +VD + D+ + A LG V L
Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSL-- 64
Query: 419 DESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKP-FKQENLSPQNAYILDTISGN 243
++ + + +NV L V + + V L+ P Q+ L ++ YILD
Sbjct: 65 --RAATPSKDINQLQKANVRLYHVYEKGKDLVVLELATPPLTQDLLQEEDFYILDQGGFK 122
Query: 242 IYVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 72
IYVW G+ ++ E+ A ++A + AK YP++ V V E AAFKQ F TW +
Sbjct: 123 IYVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSE 179
Score = 43.2 bits (97), Expect = 0.001
Identities = 54/230 (23%), Positives = 97/230 (42%), Gaps = 6/230 (2%)
Frame = -1
Query: 749 NHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKN 576
+H + + R+FQV+G + R +V + +S+N D+F+L + Y++ G+
Sbjct: 328 HHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNG 387
Query: 575 VEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDD 396
++ A + ++ + + F+ ALG P S
Sbjct: 388 DQREMARVVVTVISRKNE---------ETVLEGQEPPHFWEALGGRA----PYPSNKRLP 434
Query: 395 QEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQA 216
+E + L E S G + + + F QE+L + +LDT I++W+G+
Sbjct: 435 EEVPSFQPR---LFECSSHMGCLVLAEVGF-FSQEDLDKYDIMLLDTWQ-EIFLWLGE-- 487
Query: 215 TANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEPAAFKQYFFTW 78
A+E +A+ QE L K +P+ + V Q EP F +FFTW
Sbjct: 488 AASEWKEAVAWGQEYL--KTHPAGRSPATPIVLVKQGHEPPTFIGWFFTW 535
>BC017491-1|AAH17491.1| 285|Homo sapiens Similar to gelsolin
(amyloidosis, Finnish type) protein.
Length = 285
Score = 66.5 bits (155), Expect = 1e-10
Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 4/224 (1%)
Frame = -1
Query: 731 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKA 558
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 62 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 121
Query: 557 ISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 378
+R Q V + + D F+ ALG S D++ + +
Sbjct: 122 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 168
Query: 377 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 198
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 169 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 224
Query: 197 QAMTKAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 72
+A+T A+ + + N +T V Q EP +F +F W D
Sbjct: 225 EALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 268
>AL513122-7|CAI14416.1| 485|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 485
Score = 66.1 bits (154), Expect = 1e-10
Identities = 35/99 (35%), Positives = 54/99 (54%), Gaps = 3/99 (3%)
Frame = -1
Query: 359 LSEVSDATGKIKVTPLS--KPFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAM 189
L +VS+ G + V+ ++ PF Q L ++ +ILD G I+VW GKQA E+ A+
Sbjct: 31 LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAAL 90
Query: 188 TKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 72
A + + +YP QV+ + + E FKQ+F WRD
Sbjct: 91 KTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRD 129
Score = 54.0 bits (124), Expect = 6e-07
Identities = 48/188 (25%), Positives = 82/188 (43%), Gaps = 2/188 (1%)
Frame = -1
Query: 731 AGAQKRMFQVKGKRDVRVRQVD--PQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKA 558
A A R+FQV+ R V+ P+ ++N D FVL + Y++VG A EK A
Sbjct: 290 APASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGA 349
Query: 557 ISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERN 378
+R Q V + + D F+ ALG S D++ + +
Sbjct: 350 QELLRVLRAQP------VQVAEGSEPD----GFWEALGGKAAYRT---SPRLKDKKMDAH 396
Query: 377 EASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKS 198
L S+ G+ + + QE+L+ + +LDT ++VW+GK + EK+
Sbjct: 397 PPR---LFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKT 452
Query: 197 QAMTKAQE 174
+A+T ++
Sbjct: 453 EALTSGED 460
>AK027778-1|BAB55361.1| 468|Homo sapiens protein ( Homo sapiens
cDNA FLJ14872 fis, clone PLACE1002655, highly similar to
ADSEVERIN. ).
Length = 468
Score = 66.1 bits (154), Expect = 1e-10
Identities = 36/96 (37%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Frame = -1
Query: 350 VSDATGKIKVTPLSK--PFKQENLSPQNAYILDT-ISGNIYVWIGKQATANEKSQAMTKA 180
VSDA+G ++VT +++ PF L + +ILD + I+VW GK A E+ AM A
Sbjct: 7 VSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTA 66
Query: 179 QELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 72
+E L NY Q+ + + E FKQ+F WRD
Sbjct: 67 EEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRD 102
Score = 55.2 bits (127), Expect = 3e-07
Identities = 54/218 (24%), Positives = 94/218 (43%), Gaps = 5/218 (2%)
Frame = -1
Query: 716 RMFQVKGKRD--VRVRQVDPQIASMNKGDVFVLDL-DNDIYVFVGEKAKNVEKLKAISFA 546
R+FQV+ R+ +VD S+N DVFVL L N Y++VG+ A E+ A A
Sbjct: 264 RLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVA 323
Query: 545 NQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASN 366
+ ++ + + + ++F+ +LG G KD ++
Sbjct: 324 SVLKCKTL----------RIQEGEEPEEFWNSLG-GKKDYQTSPLLETQAEDHPPR---- 368
Query: 365 VILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMT 186
L S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++
Sbjct: 369 --LYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLK 425
Query: 185 KAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 78
A+ L + + + Q EP F +F W
Sbjct: 426 SAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 463
>BC004300-1|AAH04300.1| 672|Homo sapiens VILL protein protein.
Length = 672
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/176 (28%), Positives = 81/176 (46%), Gaps = 2/176 (1%)
Frame = -1
Query: 593 GEKAKNVEKLKAISFANQVRDQDHHG-RGRVDIVDKYSSDVDVQKFFTA-LGSGVKDLVP 420
G K EK + ++ +RD++ G R ++ +VD + D+ + A LG V L
Sbjct: 7 GPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSL-- 64
Query: 419 DESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNI 240
++ + + +NV L V + GK + L ++ YILD I
Sbjct: 65 --RAATPSKDINQLQKANVRLYHVYEK-GK------------DLLQEEDFYILDQGGFKI 109
Query: 239 YVWIGKQATANEKSQAMTKAQELLNAKNYPSWVQVTRVLQNTEPAAFKQYFFTWRD 72
YVW G+ ++ E+ A ++A + AK YP++ V V E AAFKQ F TW +
Sbjct: 110 YVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSE 165
Score = 43.2 bits (97), Expect = 0.001
Identities = 54/230 (23%), Positives = 97/230 (42%), Gaps = 6/230 (2%)
Frame = -1
Query: 749 NHVVTNAGAQKRMFQVKG--KRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKN 576
+H + + R+FQV+G + R +V + +S+N D+F+L + Y++ G+
Sbjct: 314 HHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNG 373
Query: 575 VEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDD 396
++ A + ++ + + F+ ALG P S
Sbjct: 374 DQREMARVVVTVISRKNE---------ETVLEGQEPPHFWEALGGRA----PYPSNKRLP 420
Query: 395 QEFERNEASNVILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQA 216
+E + L E S G + + + F QE+L + +LDT I++W+G+
Sbjct: 421 EEVPSFQPR---LFECSSHMGCLVLAEVGF-FSQEDLDKYDIMLLDTWQ-EIFLWLGE-- 473
Query: 215 TANEKSQAMTKAQELLNAKNYPSW----VQVTRVLQNTEPAAFKQYFFTW 78
A+E +A+ QE L K +P+ + V Q EP F +FFTW
Sbjct: 474 AASEWKEAVAWGQEYL--KTHPAGRSPATPIVLVKQGHEPPTFIGWFFTW 521
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 62.1 bits (144), Expect = 2e-09
Identities = 36/122 (29%), Positives = 65/122 (53%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQKRMFQVKGKRDVRVRQVDPQIASMNKGDVF 630
F F ++Y+EGG SGF + V + RM++V GK+++++ V + S++ VF
Sbjct: 577 FLQVFDNDISYIEGGTASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVF 635
Query: 629 VLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTA 450
+LD DIYV+ G +A KA FA ++ + G+ + ++ ++ +F+ A
Sbjct: 636 LLDRGLDIYVWRGAQATLSSTTKARLFAEKINKNERKGKAEITLL---VQGQELPEFWEA 692
Query: 449 LG 444
LG
Sbjct: 693 LG 694
Score = 37.1 bits (82), Expect = 0.075
Identities = 25/77 (32%), Positives = 40/77 (51%)
Frame = -1
Query: 329 IKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYP 150
IK+ P+ P K +L P+ ++LD +IYVW G QAT + ++A A E +N
Sbjct: 617 IKLEPV--PLKGTSLDPRFVFLLDR-GLDIYVWRGAQATLSSTTKARLFA-EKINKNERK 672
Query: 149 SWVQVTRVLQNTEPAAF 99
++T ++Q E F
Sbjct: 673 GKAEITLLVQGQELPEF 689
>AL160060-2|CAH71300.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 60.1 bits (139), Expect = 9e-09
Identities = 52/190 (27%), Positives = 86/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 713 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 534
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 533 DQDHHGRGRV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 363
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1559
Query: 362 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 195
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1560 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1618
Query: 194 AMTKAQELLN 165
A A+ L N
Sbjct: 1619 AFQLAKHLWN 1628
>AL160060-1|CAH71301.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 60.1 bits (139), Expect = 9e-09
Identities = 52/190 (27%), Positives = 86/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 713 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 534
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 533 DQDHHGRGRV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 363
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1133
Query: 362 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 195
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1134 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1192
Query: 194 AMTKAQELLN 165
A A+ L N
Sbjct: 1193 AFQLAKHLWN 1202
>AL158167-3|CAI15237.1| 2214|Homo sapiens supervillin protein.
Length = 2214
Score = 60.1 bits (139), Expect = 9e-09
Identities = 52/190 (27%), Positives = 86/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 713 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 534
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 533 DQDHHGRGRV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 363
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1559
Query: 362 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 195
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1560 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1618
Query: 194 AMTKAQELLN 165
A A+ L N
Sbjct: 1619 AFQLAKHLWN 1628
>AL158167-2|CAI15236.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 60.1 bits (139), Expect = 9e-09
Identities = 52/190 (27%), Positives = 86/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 713 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 534
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 533 DQDHHGRGRV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 363
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1133
Query: 362 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 195
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1134 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1192
Query: 194 AMTKAQELLN 165
A A+ L N
Sbjct: 1193 AFQLAKHLWN 1202
>AF109135-1|AAD14682.1| 2214|Homo sapiens archvillin protein.
Length = 2214
Score = 60.1 bits (139), Expect = 9e-09
Identities = 52/190 (27%), Positives = 86/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 713 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 534
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504
Query: 533 DQDHHGRGRV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 363
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1559
Query: 362 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 195
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1560 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1618
Query: 194 AMTKAQELLN 165
A A+ L N
Sbjct: 1619 AFQLAKHLWN 1628
>AF051851-1|AAC64696.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 60.1 bits (139), Expect = 9e-09
Identities = 52/190 (27%), Positives = 86/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 713 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 534
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 533 DQDHHGRGRV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 363
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1133
Query: 362 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 195
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1134 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1192
Query: 194 AMTKAQELLN 165
A A+ L N
Sbjct: 1193 AFQLAKHLWN 1202
>AF051850-1|AAC64695.1| 1788|Homo sapiens supervillin protein.
Length = 1788
Score = 60.1 bits (139), Expect = 9e-09
Identities = 52/190 (27%), Positives = 86/190 (45%), Gaps = 7/190 (3%)
Frame = -1
Query: 713 MFQVKGKRDVRVRQVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVR 534
+ Q+KG+R V+ R V+P+ +++N GD F+L + +++VGE A +EK KA A ++
Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078
Query: 533 DQDHHGRGRV---DIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNV 363
+ G I + ++ K F L G + GD +E E EA+ +
Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSY----QSAGDPKEDELYEAA-I 1133
Query: 362 ILSEVSDATGKIKVTP----LSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQ 195
I + K+ P K K L P+ + D +YVW GK+ T ++
Sbjct: 1134 IETNCIYRLMDDKLVPDDDYWGKIPKCSLLQPKEVLVFD-FGSEVYVWHGKEVTLAQRKI 1192
Query: 194 AMTKAQELLN 165
A A+ L N
Sbjct: 1193 AFQLAKHLWN 1202
>AL513122-9|CAI14417.1| 207|Homo sapiens gelsolin (amyloidosis,
Finnish type) protein.
Length = 207
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 2/200 (1%)
Frame = -1
Query: 665 PQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHGRGRVDIVDKY 486
P+ ++N D FVL + Y++VG A EK A +R Q V + +
Sbjct: 8 PKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQP------VQVAEGS 61
Query: 485 SSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGKIKVTPLSK 306
D F+ ALG S D++ + + L S+ G+ + +
Sbjct: 62 EPD----GFWEALGGKAAYRT---SPRLKDKKMDAHPPR---LFACSNKIGRFVIEEVPG 111
Query: 305 PFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELL--NAKNYPSWVQVT 132
QE+L+ + +LDT ++VW+GK + EK++A+T A+ + + N +T
Sbjct: 112 ELMQEDLATDDVMLLDTWD-QVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPIT 170
Query: 131 RVLQNTEPAAFKQYFFTWRD 72
V Q EP +F +F W D
Sbjct: 171 VVKQGFEPPSFVGWFLGWDD 190
>AK075198-1|BAC11465.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ90717 fis, clone PLACE1008657, highly similar to
Bovine mRNA for adseverin. ).
Length = 396
Score = 55.2 bits (127), Expect = 3e-07
Identities = 54/218 (24%), Positives = 94/218 (43%), Gaps = 5/218 (2%)
Frame = -1
Query: 716 RMFQVKGKRD--VRVRQVDPQIASMNKGDVFVLDL-DNDIYVFVGEKAKNVEKLKAISFA 546
R+FQV+ R+ +VD S+N DVFVL L N Y++VG+ A E+ A A
Sbjct: 192 RLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVA 251
Query: 545 NQVRDQDHHGRGRVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASN 366
+ ++ + + + ++F+ +LG G KD ++
Sbjct: 252 SVLKCKTL----------RIQEGEEPEEFWNSLG-GKKDYQTSPLLETQAEDHPPR---- 296
Query: 365 VILSEVSDATGKIKVTPLSKPFKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMT 186
L S+ TG+ + + F Q++L+ + +LD I++WIGK A EK +++
Sbjct: 297 --LYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWE-QIFIWIGKDANEVEKKESLK 353
Query: 185 KAQELL--NAKNYPSWVQVTRVLQNTEPAAFKQYFFTW 78
A+ L + + + Q EP F +F W
Sbjct: 354 SAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 391
>U12026-1|AAA92670.1| 172|Homo sapiens Cap-G protein.
Length = 172
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/65 (44%), Positives = 38/65 (58%), Gaps = 1/65 (1%)
Frame = -1
Query: 809 FXSYFQTPLNYLEGGNPSGFNHVVTNAGAQ-KRMFQVKGKRDVRVRQVDPQIASMNKGDV 633
F SYF L Y EGG S F+ T A A K+++QVKGK+++R + S N GD
Sbjct: 106 FMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDC 165
Query: 632 FVLDL 618
F+LDL
Sbjct: 166 FILDL 170
>AB209574-1|BAD92811.1| 326|Homo sapiens villin-like variant
protein.
Length = 326
Score = 40.3 bits (90), Expect = 0.008
Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Frame = -1
Query: 302 FKQENLSPQNAYILDTISGNIYVWIGKQATANEKSQAMTKAQELLNAKNYPSW----VQV 135
F QE+L + +LDT I++W+G+ A+E +A+ QE L K +P+ +
Sbjct: 194 FSQEDLDKYDIMLLDTWQ-EIFLWLGE--AASEWKEAVAWGQEYL--KTHPAGRSPATPI 248
Query: 134 TRVLQNTEPAAFKQYFFTW 78
V Q EP F +FFTW
Sbjct: 249 VLVKQGHEPPTFIGWFFTW 267
>U27381-1|AAA96010.1| 1447|Homo sapiens protein ( Human Menkes
disease gene (ATP7A), partial exon 23, partial cds. ).
Length = 1447
Score = 32.7 bits (71), Expect = 1.6
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 5/111 (4%)
Frame = +3
Query: 228 DPNVNVARYGVQNIRVLWTQVLLLERLR*WRHFDLSRGV*HFRENHVASF---IPFELLV 398
DP + R + I L + L+++ R H D R + +R + + S IP L+
Sbjct: 609 DPEIIGPRDIIHTIESLGFEASLVKKDRSASHLDHKREIRQWRRSFLVSLFFCIPVMGLM 668
Query: 399 VSAGALIRH--QILNS*TKSREEFLNVHIARVLVHNIDSSASVMILIPYLI 545
+ + H + ++ S+EE +N+H + L I SVM L+ +L+
Sbjct: 669 IYMMVMDHHFATLHHNQNMSKEEMINLHSSMFLERQILPGLSVMNLLSFLL 719
>AL645821-1|CAI42806.1| 1500|Homo sapiens ATPase, Cu++ transporting,
alpha polypeptide (Menkes syndrome) protein.
Length = 1500
Score = 32.7 bits (71), Expect = 1.6
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 5/111 (4%)
Frame = +3
Query: 228 DPNVNVARYGVQNIRVLWTQVLLLERLR*WRHFDLSRGV*HFRENHVASF---IPFELLV 398
DP + R + I L + L+++ R H D R + +R + + S IP L+
Sbjct: 609 DPEIIGPRDIIHTIESLGFEASLVKKDRSASHLDHKREIRQWRRSFLVSLFFCIPVMGLM 668
Query: 399 VSAGALIRH--QILNS*TKSREEFLNVHIARVLVHNIDSSASVMILIPYLI 545
+ + H + ++ S+EE +N+H + L I SVM L+ +L+
Sbjct: 669 IYMMVMDHHFATLHHNQNMSKEEMINLHSSMFLERQILPGLSVMNLLSFLL 719
>Z94801-1|CAB08162.2| 1376|Homo sapiens Menkes Disease (ATP7A)
protein.
Length = 1376
Score = 32.3 bits (70), Expect = 2.1
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 5/111 (4%)
Frame = +3
Query: 228 DPNVNVARYGVQNIRVLWTQVLLLERLR*WRHFDLSRGV*HFRENHVASF---IPFELLV 398
DP + R + I L + L+++ R H D R + +R + + S IP L+
Sbjct: 609 DPEIIGPRDIIHTIEGLGFEASLVKKDRSASHLDHKREIRQWRRSFLVSLFFCIPVMGLM 668
Query: 399 VSAGALIRH--QILNS*TKSREEFLNVHIARVLVHNIDSSASVMILIPYLI 545
+ + H + ++ S+EE +N+H + L I SVM L+ +L+
Sbjct: 669 IYMMVMDHHFATLHHNQNMSKEEMINLHSSMFLERQILPGLSVMNLLSFLL 719
>X82336-1|CAB94714.1| 1500|Homo sapiens Menkes disease protein.
Length = 1500
Score = 31.5 bits (68), Expect = 3.7
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 5/111 (4%)
Frame = +3
Query: 228 DPNVNVARYGVQNIRVLWTQVLLLERLR*WRHFDLSRGV*HFRENHVASF---IPFELLV 398
DP + R + I L + L+++ R H D R + +R + + S IP L+
Sbjct: 609 DPEIIGPRDIIHTIESLGFEASLVKKDRSASHLDHKREIRQWRRSFLVSLFFCIPVMGLM 668
Query: 399 VSAGALIRH--QILNS*TKSREEFLNVHIARVLVHNIDSSASVMILIPYLI 545
+ H + ++ S+EE +N+H + L I SVM L+ +L+
Sbjct: 669 TYMMVMDHHFATLHHNQNMSKEEMINLHSSMFLERQILPGLSVMNLLSFLL 719
>L06133-1|AAA35580.1| 1500|Homo sapiens Cu++-transporting P-type
ATPase protein.
Length = 1500
Score = 31.5 bits (68), Expect = 3.7
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 5/111 (4%)
Frame = +3
Query: 228 DPNVNVARYGVQNIRVLWTQVLLLERLR*WRHFDLSRGV*HFRENHVASF---IPFELLV 398
DP + R + I L + L+++ R H D R + +R + + S IP L+
Sbjct: 609 DPEIIGPRDIIHTIESLGFEASLVKKDRSASHLDHKREIRQWRRSFLVSLFFCIPVMGLM 668
Query: 399 VSAGALIRH--QILNS*TKSREEFLNVHIARVLVHNIDSSASVMILIPYLI 545
+ H + ++ S+EE +N+H + L I SVM L+ +L+
Sbjct: 669 TYMMVMDHHFATLHHNQNMSKEEMINLHSSMFLERQILPGLSVMNLLSFLL 719
>DQ012935-1|AAY22174.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2 protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.7
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 369 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 241
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>BC112342-1|AAI12343.1| 1553|Homo sapiens TRPM2 protein protein.
Length = 1553
Score = 31.5 bits (68), Expect = 3.7
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 369 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 241
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AY603182-1|AAT12288.1| 846|Homo sapiens TRPM2-S protein.
Length = 846
Score = 31.5 bits (68), Expect = 3.7
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 369 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 241
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AP001754-4|BAA95563.1| 1503|Homo sapiens transient receptor
potential-related channel 7, a novel putative Ca2+
channel p protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.7
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 369 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 241
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AJ878416-1|CAI47593.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2 protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.7
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 369 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 241
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AJ417076-1|CAD01139.1| 1449|Homo sapiens putative TRP cation
channel protein.
Length = 1449
Score = 31.5 bits (68), Expect = 3.7
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 369 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 241
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AB166746-1|BAD83706.1| 1289|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2,
striatum sh protein.
Length = 1289
Score = 31.5 bits (68), Expect = 3.7
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 369 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 241
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 197 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 240
>AB166745-1|BAD83705.1| 1503|Homo sapiens transient receptor
potential cation channel, subfamily M, member 2, long
form ( protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.7
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 369 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 241
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>AB001535-1|BAA34700.1| 1503|Homo sapiens KNP3 protein.
Length = 1503
Score = 31.5 bits (68), Expect = 3.7
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Frame = -3
Query: 369 QRDSL*SVRRHGKD-QSDATIEAFQARELESTERVYFGHHIWQH 241
+R L +V R GKD Q D + QA S + +FGH W H
Sbjct: 411 RRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHENWDH 454
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 30.3 bits (65), Expect = 8.6
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = -2
Query: 772 REGIRPVLTTSSRTREPRNECSRSRGSEMSALDK 671
REG P+LT S+R EC G++++A DK
Sbjct: 510 REGETPLLTASARGYHDIVECLAEHGADLNACDK 543
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 30.3 bits (65), Expect = 8.6
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = -2
Query: 772 REGIRPVLTTSSRTREPRNECSRSRGSEMSALDK 671
REG P+LT S+R EC G++++A DK
Sbjct: 509 REGETPLLTASARGYHDIVECLAEHGADLNACDK 542
>BC129991-1|AAI29992.1| 754|Homo sapiens PERQ1 protein protein.
Length = 754
Score = 30.3 bits (65), Expect = 8.6
Identities = 23/77 (29%), Positives = 35/77 (45%)
Frame = -1
Query: 509 RVDIVDKYSSDVDVQKFFTALGSGVKDLVPDESTGGDDQEFERNEASNVILSEVSDATGK 330
R+D D+ D F L G K+ +P+E D Q E E + L E G
Sbjct: 14 RLDDEDEEMGTFDASGAFLPLKKGPKEPIPEEQE-LDFQGLEEEEEPSEGLEEEGPEAGG 72
Query: 329 IKVTPLSKPFKQENLSP 279
++TPL P ++++ SP
Sbjct: 73 KELTPL-PPQEEKSSSP 88
>BC113847-1|AAI13848.1| 956|Homo sapiens thrombospondin 3,
precursor protein.
Length = 956
Score = 30.3 bits (65), Expect = 8.6
Identities = 17/53 (32%), Positives = 26/53 (49%)
Frame = -1
Query: 674 QVDPQIASMNKGDVFVLDLDNDIYVFVGEKAKNVEKLKAISFANQVRDQDHHG 516
Q+DP +N+G V +++D + VG A N + AN V D D+ G
Sbjct: 741 QIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHANTVTDDDYAG 793
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 30.3 bits (65), Expect = 8.6
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = -2
Query: 772 REGIRPVLTTSSRTREPRNECSRSRGSEMSALDK 671
REG P+LT S+R EC G++++A DK
Sbjct: 509 REGETPLLTASARGYHDIVECLAEHGADLNACDK 542
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 30.3 bits (65), Expect = 8.6
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = -2
Query: 772 REGIRPVLTTSSRTREPRNECSRSRGSEMSALDK 671
REG P+LT S+R EC G++++A DK
Sbjct: 509 REGETPLLTASARGYHDIVECLAEHGADLNACDK 542
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 30.3 bits (65), Expect = 8.6
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = -2
Query: 772 REGIRPVLTTSSRTREPRNECSRSRGSEMSALDK 671
REG P+LT S+R EC G++++A DK
Sbjct: 509 REGETPLLTASARGYHDIVECLAEHGADLNACDK 542
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 30.3 bits (65), Expect = 8.6
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = -2
Query: 772 REGIRPVLTTSSRTREPRNECSRSRGSEMSALDK 671
REG P+LT S+R EC G++++A DK
Sbjct: 509 REGETPLLTASARGYHDIVECLAEHGADLNACDK 542
>AK128318-1|BAC87382.1| 421|Homo sapiens protein ( Homo sapiens
cDNA FLJ46459 fis, clone THYMU3020970. ).
Length = 421
Score = 30.3 bits (65), Expect = 8.6
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = -2
Query: 799 ISRHP*TIWREGIRPVLTTSSRTREPRNECSRSRGSE 689
+S H + W PV+ +EP++ CSRS GS+
Sbjct: 182 VSAHRRSRWSPPPVPVVRVGEEVQEPQSSCSRSPGSQ 218
>AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ45958 fis, clone PLACE7011559, highly similar
to Death-associated protein kinase 1 (EC 2.7.1.-). ).
Length = 337
Score = 30.3 bits (65), Expect = 8.6
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = -2
Query: 772 REGIRPVLTTSSRTREPRNECSRSRGSEMSALDK 671
REG P+LT S+R EC G++++A DK
Sbjct: 63 REGETPLLTASARGYHDIVECLAEHGADLNACDK 96
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 30.3 bits (65), Expect = 8.6
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = -2
Query: 772 REGIRPVLTTSSRTREPRNECSRSRGSEMSALDK 671
REG P+LT S+R EC G++++A DK
Sbjct: 512 REGETPLLTASARGYHDIVECLAEHGADLNACDK 545
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,404,451
Number of Sequences: 237096
Number of extensions: 2262737
Number of successful extensions: 8771
Number of sequences better than 10.0: 66
Number of HSP's better than 10.0 without gapping: 8428
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8709
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10036353240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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