Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmte10b05
(852 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 317 4e-86
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 317 4e-86
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 317 4e-86
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 317 4e-86
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 317 4e-86
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 317 4e-86
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 317 4e-86
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 317 4e-86
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 317 4e-86
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 317 4e-86
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 317 4e-86
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 316 7e-86
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 316 9e-86
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 311 2e-84
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 302 1e-81
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 302 1e-81
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 302 1e-81
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 302 1e-81
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 301 2e-81
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 300 3e-81
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 270 6e-72
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 270 6e-72
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 270 6e-72
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 270 6e-72
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 270 6e-72
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 270 6e-72
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 270 6e-72
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 270 6e-72
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 260 3e-69
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 257 3e-68
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 257 3e-68
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 257 3e-68
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 257 3e-68
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 257 3e-68
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 257 3e-68
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 257 3e-68
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 256 6e-68
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 256 6e-68
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 256 7e-68
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 256 7e-68
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 256 7e-68
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 256 7e-68
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 256 7e-68
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 256 7e-68
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 256 7e-68
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 256 7e-68
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 256 7e-68
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 256 1e-67
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 256 1e-67
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 256 1e-67
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 256 1e-67
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 256 1e-67
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 256 1e-67
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 256 1e-67
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 256 1e-67
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 256 1e-67
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 256 1e-67
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 256 1e-67
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 254 3e-67
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 253 5e-67
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 253 7e-67
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 250 5e-66
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 248 2e-65
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 248 3e-65
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 248 3e-65
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 248 3e-65
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 248 3e-65
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 248 3e-65
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 247 3e-65
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 247 3e-65
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 246 1e-64
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 241 2e-63
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 241 2e-63
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 241 2e-63
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 241 2e-63
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 232 1e-60
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 228 2e-59
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 224 3e-58
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 224 3e-58
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 212 2e-54
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 196 1e-49
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 196 1e-49
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 134 5e-31
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 134 5e-31
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 109 1e-23
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 107 5e-23
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 90 1e-17
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 77 6e-14
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 77 6e-14
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 77 6e-14
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 75 2e-13
AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-relate... 73 1e-12
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 66 2e-10
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 45 3e-04
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 40 0.015
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 40 0.015
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 40 0.015
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 40 0.015
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 40 0.015
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 40 0.015
BC030254-1|AAH30254.1| 433|Homo sapiens chromosome 20 open read... 35 0.33
AL031658-5|CAI42581.1| 433|Homo sapiens chromosome 20 open read... 35 0.33
BC111958-1|AAI11959.1| 710|Homo sapiens ral guanine nucleotide ... 34 0.75
BC101756-1|AAI01757.1| 710|Homo sapiens ral guanine nucleotide ... 34 0.75
AK074082-1|BAB84908.1| 497|Homo sapiens FLJ00153 protein protein. 34 0.75
AB058756-1|BAB47482.1| 708|Homo sapiens KIAA1853 protein protein. 33 1.00
AJ009794-1|CAA08833.1| 362|Homo sapiens hug-1 protein. 33 1.3
Z99716-2|CAI41689.1| 177|Homo sapiens protein ( Human DNA seque... 32 3.0
AL833963-1|CAD38811.1| 453|Homo sapiens hypothetical protein pr... 32 3.0
BX640881-1|CAE45937.1| 999|Homo sapiens hypothetical protein pr... 31 5.3
AY576779-1|AAT39521.1| 860|Homo sapiens nucleolar protein with ... 31 5.3
AB029007-1|BAA83036.2| 778|Homo sapiens KIAA1084 protein protein. 31 5.3
U30826-1|AAA93070.1| 272|Homo sapiens SRp40-1 protein. 31 7.0
BT007089-1|AAP35752.1| 272|Homo sapiens splicing factor, argini... 31 7.0
BC040209-1|AAH40209.1| 272|Homo sapiens splicing factor, argini... 31 7.0
BC018823-1|AAH18823.1| 272|Homo sapiens splicing factor, argini... 31 7.0
AY130006-1|AAN05090.1| 90|Homo sapiens MU-MB-2.76 protein. 31 7.0
AB209804-1|BAD93041.1| 326|Homo sapiens CS0DF038YO05 variant pr... 31 7.0
X05562-1|CAA29076.1| 1043|Homo sapiens protein ( Human mRNA for ... 30 9.3
EF471359-1|ABO86192.1| 270|Homo sapiens MHC class I antigen pro... 30 9.3
AL162417-13|CAI13418.1| 294|Homo sapiens globoside alpha-1,3-N-... 30 9.3
AL161773-3|CAH71366.2| 1712|Homo sapiens collagen type IV alpha ... 30 9.3
AL159153-1|CAH72050.2| 1712|Homo sapiens collagen type IV alpha ... 30 9.3
AL139385-2|CAI17005.2| 1712|Homo sapiens collagen type IV alpha ... 30 9.3
AK074639-1|BAC11106.1| 294|Homo sapiens 40). protein. 30 9.3
AJ238850-1|CAB52754.1| 1203|Homo sapiens hyperpolarization-activ... 30 9.3
AJ132429-1|CAB42604.1| 1203|Homo sapiens hyperpolarization-activ... 30 9.3
AF117899-1|AAF27280.1| 363|Homo sapiens LDLR-FUT fusion protein... 30 9.3
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 317 bits (778), Expect = 4e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 317 bits (778), Expect = 4e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 317 bits (778), Expect = 4e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 317 bits (778), Expect = 4e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 317 bits (778), Expect = 4e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 317 bits (778), Expect = 4e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 317 bits (778), Expect = 4e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 317 bits (778), Expect = 4e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 317 bits (778), Expect = 4e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 317 bits (778), Expect = 4e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 317 bits (778), Expect = 4e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 316 bits (776), Expect = 7e-86
Identities = 147/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPIGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 316 bits (775), Expect = 9e-86
Identities = 146/269 (54%), Positives = 194/269 (72%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP ++ FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILSKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 311 bits (764), Expect = 2e-84
Identities = 146/269 (54%), Positives = 193/269 (71%), Gaps = 2/269 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 49 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DT AME LV EGLVK+IG+SNFN Q+E
Sbjct: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L +K P VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDP++KAIA + KT AQVLIR+ + +VIPKSVT RIA NF V DF+LS +D+
Sbjct: 229 LEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENEEF 51
+ S++ R+ + + HK +PF +EEF
Sbjct: 289 LLSYNRNWRVCALLSCTSHKDYPF-HEEF 316
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 302 bits (741), Expect = 1e-81
Identities = 147/267 (55%), Positives = 184/267 (68%), Gaps = 2/267 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVGEAI KI+E V REDLFI SKLW TF LVR A ++TL +L + YLD+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWPQ +K LFP D G ++D W+AME LV EGLVK++GVSNF+ Q+E
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+LL +K PV NQVECHPYL Q++L ++C ++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 KLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDPK+K IA + KT AQVLIR+ I IVIPKSVT +RI N V DFKLS E++A
Sbjct: 229 LEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMAT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENE 57
I SF+ R + S + +PF+ E
Sbjct: 289 ILSFNRNWRACNVLQSSHLEDYPFDAE 315
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 302 bits (741), Expect = 1e-81
Identities = 147/267 (55%), Positives = 184/267 (68%), Gaps = 2/267 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVGEAI KI+E V REDLFI SKLW TF LVR A ++TL +L + YLD+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWPQ +K LFP D G ++D W+AME LV EGLVK++GVSNF+ Q+E
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+LL +K PV NQVECHPYL Q++L ++C ++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 KLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDPK+K IA + KT AQVLIR+ I IVIPKSVT +RI N V DFKLS E++A
Sbjct: 229 LEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMAT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENE 57
I SF+ R + S + +PF+ E
Sbjct: 289 ILSFNRNWRACNVLQSSHLEDYPFDAE 315
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 302 bits (741), Expect = 1e-81
Identities = 147/267 (55%), Positives = 184/267 (68%), Gaps = 2/267 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVGEAI KI+E V REDLFI SKLW TF LVR A ++TL +L + YLD+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWPQ +K LFP D G ++D W+AME LV EGLVK++GVSNF+ Q+E
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+LL +K PV NQVECHPYL Q++L ++C ++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 KLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDPK+K IA + KT AQVLIR+ I IVIPKSVT +RI N V DFKLS E++A
Sbjct: 229 LEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMAT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENE 57
I SF+ R + S + +PF+ E
Sbjct: 289 ILSFNRNWRACNVLQSSHLEDYPFDAE 315
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 302 bits (741), Expect = 1e-81
Identities = 147/267 (55%), Positives = 184/267 (68%), Gaps = 2/267 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVGEAI KI+E V REDLFI SKLW TF LVR A ++TL +L + YLD+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWPQ +K LFP D G ++D W+AME LV EGLVK++GVSNF+ Q+E
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+LL +K PV NQVECHPYL Q++L ++C ++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 KLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDPK+K IA + KT AQVLIR+ I IVIPKSVT +RI N V DFKLS E++A
Sbjct: 229 LEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMAT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENE 57
I SF+ R + S + +PF+ E
Sbjct: 289 ILSFNRNWRACNVLQSSHLEDYPFDAE 315
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 301 bits (739), Expect = 2e-81
Identities = 147/267 (55%), Positives = 183/267 (68%), Gaps = 2/267 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVGEAI KI+E V REDLFI SKLW TF LVR A ++TL +L + YLD+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWPQ +K LFP D G ++D W+AME LV EGLVK++GVSNF+ Q+E
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+LL +K PV NQVECHPYL Q++L ++C ++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 KLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDPK+K IA + KT AQVLIR+ I IVIPKSVT +RI N V DFKLS E++A
Sbjct: 229 LEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMAT 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENE 57
I SF+ R + S + +PF E
Sbjct: 289 ILSFNRNWRACNVLQSSHLEDYPFNAE 315
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 300 bits (737), Expect = 3e-81
Identities = 146/267 (54%), Positives = 184/267 (68%), Gaps = 2/267 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVGEAI KI+E V REDLFI SKLW TF LVR A ++TL + + YLD+Y
Sbjct: 49 YQNEHEVGEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVY 108
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWPQ +K LFP D G ++D W+AME LV EGLVK++GVSNF+ Q+E
Sbjct: 109 LIHWPQGFKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIE 168
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+LL +K PV NQVECHPYL Q++L ++C ++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 169 KLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSL 228
Query: 317 MEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVAL 138
+EDPK+K IA + KT AQVLIR+ I IVIPKSVT +RI N V DFKLS E++A+
Sbjct: 229 LEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMAI 288
Query: 137 IDSFDCGGRLVPMTASLGHKHHPFENE 57
I SF+ R + S + +PF+ E
Sbjct: 289 ILSFNRNWRACNVLQSSHLEDYPFDAE 315
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 270 bits (661), Expect = 6e-72
Identities = 124/253 (49%), Positives = 179/253 (70%), Gaps = 2/253 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEG-VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 675
YGNE E+GEA+ + G V RE+LF+TSKLWNT H P+ V AL++TL +L ++YLDL
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 674 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 495
YL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G+SNFNS+Q+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 494 ERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLM 315
+ +L A+V+P V QVECHPYL Q L C+ARG+++TAYSPLGS DR W PD+P L+
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 314 EDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALI 135
E+P + A+A++ G++ AQ+L+R+Q+ I IPKS+T SRI N V DF S E++ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 134 DSFDCGGR-LVPM 99
++ + R +VPM
Sbjct: 290 NALNKNWRYIVPM 302
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 270 bits (661), Expect = 6e-72
Identities = 124/253 (49%), Positives = 179/253 (70%), Gaps = 2/253 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEG-VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 675
YGNE E+GEA+ + G V RE+LF+TSKLWNT H P+ V AL++TL +L ++YLDL
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 674 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 495
YL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G+SNFNS+Q+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 494 ERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLM 315
+ +L A+V+P V QVECHPYL Q L C+ARG+++TAYSPLGS DR W PD+P L+
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 314 EDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALI 135
E+P + A+A++ G++ AQ+L+R+Q+ I IPKS+T SRI N V DF S E++ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 134 DSFDCGGR-LVPM 99
++ + R +VPM
Sbjct: 290 NALNKNWRYIVPM 302
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 270 bits (661), Expect = 6e-72
Identities = 124/253 (49%), Positives = 179/253 (70%), Gaps = 2/253 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEG-VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 675
YGNE E+GEA+ + G V RE+LF+TSKLWNT H P+ V AL++TL +L ++YLDL
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 674 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 495
YL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G+SNFNS+Q+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 494 ERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLM 315
+ +L A+V+P V QVECHPYL Q L C+ARG+++TAYSPLGS DR W PD+P L+
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 314 EDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALI 135
E+P + A+A++ G++ AQ+L+R+Q+ I IPKS+T SRI N V DF S E++ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 134 DSFDCGGR-LVPM 99
++ + R +VPM
Sbjct: 290 NALNKNWRYIVPM 302
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 270 bits (661), Expect = 6e-72
Identities = 124/253 (49%), Positives = 179/253 (70%), Gaps = 2/253 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEG-VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 675
YGNE E+GEA+ + G V RE+LF+TSKLWNT H P+ V AL++TL +L ++YLDL
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 674 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 495
YL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G+SNFNS+Q+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 494 ERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLM 315
+ +L A+V+P V QVECHPYL Q L C+ARG+++TAYSPLGS DR W PD+P L+
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 314 EDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALI 135
E+P + A+A++ G++ AQ+L+R+Q+ I IPKS+T SRI N V DF S E++ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 134 DSFDCGGR-LVPM 99
++ + R +VPM
Sbjct: 290 NALNKNWRYIVPM 302
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 270 bits (661), Expect = 6e-72
Identities = 124/253 (49%), Positives = 179/253 (70%), Gaps = 2/253 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEG-VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 675
YGNE E+GEA+ + G V RE+LF+TSKLWNT H P+ V AL++TL +L ++YLDL
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 674 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 495
YL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G+SNFNS+Q+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 494 ERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLM 315
+ +L A+V+P V QVECHPYL Q L C+ARG+++TAYSPLGS DR W PD+P L+
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 314 EDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALI 135
E+P + A+A++ G++ AQ+L+R+Q+ I IPKS+T SRI N V DF S E++ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 134 DSFDCGGR-LVPM 99
++ + R +VPM
Sbjct: 290 NALNKNWRYIVPM 302
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 270 bits (661), Expect = 6e-72
Identities = 124/253 (49%), Positives = 179/253 (70%), Gaps = 2/253 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEG-VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 675
YGNE E+GEA+ + G V RE+LF+TSKLWNT H P+ V AL++TL +L ++YLDL
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 674 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 495
YL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G+SNFNS+Q+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 494 ERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLM 315
+ +L A+V+P V QVECHPYL Q L C+ARG+++TAYSPLGS DR W PD+P L+
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 314 EDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALI 135
E+P + A+A++ G++ AQ+L+R+Q+ I IPKS+T SRI N V DF S E++ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 134 DSFDCGGR-LVPM 99
++ + R +VPM
Sbjct: 290 NALNKNWRYIVPM 302
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 270 bits (661), Expect = 6e-72
Identities = 124/253 (49%), Positives = 179/253 (70%), Gaps = 2/253 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEG-VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 675
YGNE E+GEA+ + G V RE+LF+TSKLWNT H P+ V AL++TL +L ++YLDL
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 674 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 495
YL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G+SNFNS+Q+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 494 ERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLM 315
+ +L A+V+P V QVECHPYL Q L C+ARG+++TAYSPLGS DR W PD+P L+
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 314 EDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALI 135
E+P + A+A++ G++ AQ+L+R+Q+ I IPKS+T SRI N V DF S E++ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 134 DSFDCGGR-LVPM 99
++ + R +VPM
Sbjct: 290 NALNKNWRYIVPM 302
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 270 bits (661), Expect = 6e-72
Identities = 124/253 (49%), Positives = 179/253 (70%), Gaps = 2/253 (0%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEG-VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 675
YGNE E+GEA+ + G V RE+LF+TSKLWNT H P+ V AL++TL +L ++YLDL
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 674 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 495
YL+HWP A++ + FP + G I + Y +TWKA+E LV +GLV+++G+SNFNS+Q+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQI 169
Query: 494 ERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQLM 315
+ +L A+V+P V QVECHPYL Q L C+ARG+++TAYSPLGS DR W PD+P L+
Sbjct: 170 DDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLL 229
Query: 314 EDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALI 135
E+P + A+A++ G++ AQ+L+R+Q+ I IPKS+T SRI N V DF S E++ +
Sbjct: 230 EEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQL 289
Query: 134 DSFDCGGR-LVPM 99
++ + R +VPM
Sbjct: 290 NALNKNWRYIVPM 302
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 260 bits (638), Expect = 3e-69
Identities = 117/200 (58%), Positives = 150/200 (75%), Gaps = 2/200 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVG AI K++E VV RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLY
Sbjct: 46 YQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLY 105
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIHWP +K FP D+SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E
Sbjct: 106 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVE 165
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRPWAKPDDPQL 318
+L + KP VNQ+ECHPYL Q++L ++C+++G+ +TAYSPLGSPDRPWAKP+DP L
Sbjct: 166 MILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSL 225
Query: 317 MEDPKLKAIADRLGKTVAQV 258
+EDP++KAIA + KT AQV
Sbjct: 226 LEDPRIKAIAAKHNKTTAQV 245
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 257 bits (630), Expect = 3e-68
Identities = 125/268 (46%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLY
Sbjct: 57 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 116
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE
Sbjct: 117 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLE 176
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPY N+ +L +FC+++ + + AYS LGS D+ W P+ P
Sbjct: 177 MILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPV 236
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 237 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 296
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID D + H ++P+ +E
Sbjct: 297 AIDGLDRNLHYFNSDSFASHPNYPYSDE 324
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 257 bits (630), Expect = 3e-68
Identities = 125/268 (46%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPY N+ +L +FC+++ + + AYS LGS D+ W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID D + H ++P+ +E
Sbjct: 295 AIDGLDRNLHYFNSDSFASHPNYPYSDE 322
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 257 bits (630), Expect = 3e-68
Identities = 125/268 (46%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPY N+ +L +FC+++ + + AYS LGS D+ W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID D + H ++P+ +E
Sbjct: 295 AIDGLDRNLHYFNSDSFASHPNYPYSDE 322
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 257 bits (630), Expect = 3e-68
Identities = 125/268 (46%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPY N+ +L +FC+++ + + AYS LGS D+ W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID D + H ++P+ +E
Sbjct: 295 AIDGLDRNLHYFNSDSFASHPNYPYSDE 322
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 257 bits (630), Expect = 3e-68
Identities = 125/268 (46%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPY N+ +L +FC+++ + + AYS LGS D+ W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID D + H ++P+ +E
Sbjct: 295 AIDGLDRNLHYFNSDSFASHPNYPYSDE 322
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 257 bits (630), Expect = 3e-68
Identities = 125/268 (46%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPY N+ +L +FC+++ + + AYS LGS D+ W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID D + H ++P+ +E
Sbjct: 295 AIDGLDRNLHYFNSDSFASHPNYPYSDE 322
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 257 bits (630), Expect = 3e-68
Identities = 125/268 (46%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPY N+ +L +FC+++ + + AYS LGS D+ W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID D + H ++P+ +E
Sbjct: 295 AIDGLDRNLHYFNSDSFASHPNYPYSDE 322
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 256 bits (628), Expect = 6e-68
Identities = 125/268 (46%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPY N+ +L +FC+++ + + AYS LGS D+ W P+ P
Sbjct: 175 IILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID D + H ++P+ +E
Sbjct: 295 AIDGLDRNLHYFNSDSFASHPNYPYSDE 322
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 256 bits (628), Expect = 6e-68
Identities = 125/268 (46%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+TFHRP+LVR AL+ +L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPY N+ +L +FC+++ + + AYS LGS D+ W P+ P
Sbjct: 175 IILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID D + H ++P+ +E
Sbjct: 295 AIDGLDRNLHYFNSDSFASHPNYPYSDE 322
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 256 bits (627), Expect = 7e-68
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 256 bits (627), Expect = 7e-68
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 256 bits (627), Expect = 7e-68
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 256 bits (627), Expect = 7e-68
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 256 bits (627), Expect = 7e-68
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 256 bits (627), Expect = 7e-68
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 256 bits (627), Expect = 7e-68
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 256 bits (627), Expect = 7e-68
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 256 bits (627), Expect = 7e-68
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 256 bits (626), Expect = 1e-67
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 256 bits (626), Expect = 1e-67
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 256 bits (626), Expect = 1e-67
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 256 bits (626), Expect = 1e-67
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 38 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 97
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE
Sbjct: 98 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLE 157
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 158 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 217
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 218 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 277
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 278 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 305
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 256 bits (626), Expect = 1e-67
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 256 bits (626), Expect = 1e-67
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 256 bits (626), Expect = 1e-67
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 256 bits (626), Expect = 1e-67
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 256 bits (626), Expect = 1e-67
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 256 bits (626), Expect = 1e-67
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 256 bits (626), Expect = 1e-67
Identities = 124/268 (46%), Positives = 173/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++PF +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPFSDE 322
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 254 bits (622), Expect = 3e-67
Identities = 123/268 (45%), Positives = 172/268 (64%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 174
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L +K PV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++P +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPISDE 322
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 253 bits (620), Expect = 5e-67
Identities = 123/268 (45%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 115 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 174
Query: 491 RLLQHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L +K PV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 175 MILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++P +E
Sbjct: 295 AIDGLNRNVRYLTLDIFAGPPNYPISDE 322
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 253 bits (619), Expect = 7e-67
Identities = 123/268 (45%), Positives = 170/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+T HRP+LVR AL+ +L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPY N+ +L +FC+++ + + AYS LGS D+ W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ +S RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLARSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID D + H ++P+ +E
Sbjct: 295 AIDGLDRNLHYFNSDSFASHPNYPYSDE 322
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 250 bits (612), Expect = 5e-66
Identities = 122/268 (45%), Positives = 168/268 (62%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG A+ SKI +G V RED+F TSKLW HRP+LVR AL+ +L + Y+DLY
Sbjct: 55 YNNEEQVGLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH P + K L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE
Sbjct: 115 LIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPY N+ +L +FC+++ + + AYS LGS D+ W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID D + H ++P+ +E
Sbjct: 295 AIDGLDRNLHYFNSDSFASHPNYPYSDE 322
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 248 bits (607), Expect = 2e-65
Identities = 120/268 (44%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
L+H+P A K + P D++GK+ F VD TW+ ME GL KSIGVSNFN +QLE
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPYLNQ +L +FC+++ + + A+S LG+ + W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
++D + R V M + H +PF +E
Sbjct: 295 VLDGLNRNYRYVVMDFVMDHPDYPFSDE 322
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 248 bits (606), Expect = 3e-65
Identities = 120/268 (44%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
L+H+P A K + P D++GK+ F VD TW+ ME GL KSIGVSNFN +QLE
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPYLNQ +L +FC+++ + + A+S LG+ + W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
++D + R V M + H +PF +E
Sbjct: 295 VLDGLNRNYRYVVMDFLMDHPDYPFSDE 322
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 248 bits (606), Expect = 3e-65
Identities = 120/268 (44%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLY
Sbjct: 40 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 99
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
L+H+P A K + P D++GK+ F VD TW+ ME GL KSIGVSNFN +QLE
Sbjct: 100 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLE 159
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPYLNQ +L +FC+++ + + A+S LG+ + W P+ P
Sbjct: 160 MILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPV 219
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 220 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 279
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
++D + R V M + H +PF +E
Sbjct: 280 VLDGLNRNYRYVVMDFLMDHPDYPFSDE 307
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 248 bits (606), Expect = 3e-65
Identities = 120/268 (44%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLY
Sbjct: 53 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 112
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
L+H+P A K + P D++GK+ F VD TW+ ME GL KSIGVSNFN +QLE
Sbjct: 113 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLE 172
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPYLNQ +L +FC+++ + + A+S LG+ + W P+ P
Sbjct: 173 MILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPV 232
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 233 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 292
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
++D + R V M + H +PF +E
Sbjct: 293 VLDGLNRNYRYVVMDFLMDHPDYPFSDE 320
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 248 bits (606), Expect = 3e-65
Identities = 120/268 (44%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
L+H+P A K + P D++GK+ F VD TW+ ME GL KSIGVSNFN +QLE
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPYLNQ +L +FC+++ + + A+S LG+ + W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
++D + R V M + H +PF +E
Sbjct: 295 VLDGLNRNYRYVVMDFLMDHPDYPFSDE 322
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 248 bits (606), Expect = 3e-65
Identities = 120/268 (44%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
L+H+P A K + P D++GK+ F VD TW+ ME GL KSIGVSNFN +QLE
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPYLNQ +L +FC+++ + + A+S LG+ + W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
++D + R V M + H +PF +E
Sbjct: 295 VLDGLNRNYRYVVMDFLMDHPDYPFSDE 322
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 247 bits (605), Expect = 3e-65
Identities = 120/268 (44%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
L+H+P A K + P D++GK+ F VD TW+ ME GL KSIGVSNFN +QLE
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPYLNQ +L +FC+++ + + A+S LG+ + W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
++D + R V M + H +PF +E
Sbjct: 295 VLDGLNRNYRYVVMDFLMDHPDYPFSDE 322
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 247 bits (605), Expect = 3e-65
Identities = 120/268 (44%), Positives = 171/268 (63%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW TF +P +V+ AL+ +L L + Y+DLY
Sbjct: 55 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLY 114
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
L+H+P A K + P D++GK+ F VD TW+ ME GL KSIGVSNFN +QLE
Sbjct: 115 LLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLE 174
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP-DRPWAKPDDPQ 321
+L + KPV NQVECHPYLNQ +L +FC+++ + + A+S LG+ + W P+ P
Sbjct: 175 MILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPV 234
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ ED+
Sbjct: 235 LLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMK 294
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
++D + R V M + H +PF +E
Sbjct: 295 VLDGLNRNYRYVVMDFLMDHPDYPFSDE 322
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 246 bits (601), Expect = 1e-64
Identities = 121/268 (45%), Positives = 168/268 (62%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW HRP+L R AL+ +L NL + Y+DLY
Sbjct: 52 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLY 111
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+A+E L KSIGVSNFN LE
Sbjct: 112 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLE 171
Query: 491 RLLQH--ATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L VKPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 172 MILNKPGLQVKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSLREEPWVDPNSPV 231
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+EDP L A+A + +T A + +RYQ+ G +V+ KS RI N V +F+L+ E++
Sbjct: 232 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 291
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + G ++P +E
Sbjct: 292 AIDGLNRNVRYLTLDIFAGPPNYPISDE 319
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 241 bits (591), Expect = 2e-63
Identities = 119/268 (44%), Positives = 162/268 (60%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVGEAI KI EG V RED+F KLW T H P++VR L+ TL L + Y+DLY
Sbjct: 58 YQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLY 117
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
+I P A+K ++P D++GK + + TW+AME GLVKS+GVSNFN +QLE
Sbjct: 118 IIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLE 177
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP-WAKPDDPQ 321
+L + KPV NQVECHPY Q +L +FC+ + ITAYSPLG+ P W P
Sbjct: 178 LILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPP 237
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L++D L ++ R KT AQ+++R+ I G +VIPKS RI NF + DF L+ E++
Sbjct: 238 LLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMK 297
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
I++ + R V + H +PF +E
Sbjct: 298 DIEALNKNVRFVELLMWRDHPEYPFHDE 325
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 241 bits (591), Expect = 2e-63
Identities = 119/268 (44%), Positives = 162/268 (60%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVGEAI KI EG V RED+F KLW T H P++VR L+ TL L + Y+DLY
Sbjct: 58 YQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLY 117
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
+I P A+K ++P D++GK + + TW+AME GLVKS+GVSNFN +QLE
Sbjct: 118 IIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLE 177
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP-WAKPDDPQ 321
+L + KPV NQVECHPY Q +L +FC+ + ITAYSPLG+ P W P
Sbjct: 178 LILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPP 237
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L++D L ++ R KT AQ+++R+ I G +VIPKS RI NF + DF L+ E++
Sbjct: 238 LLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMK 297
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
I++ + R V + H +PF +E
Sbjct: 298 DIEALNKNVRFVELLMWRDHPEYPFHDE 325
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 241 bits (591), Expect = 2e-63
Identities = 119/268 (44%), Positives = 162/268 (60%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVGEAI KI EG V RED+F KLW T H P++VR L+ TL L + Y+DLY
Sbjct: 58 YQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLY 117
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
+I P A+K ++P D++GK + + TW+AME GLVKS+GVSNFN +QLE
Sbjct: 118 IIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLE 177
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP-WAKPDDPQ 321
+L + KPV NQVECHPY Q +L +FC+ + ITAYSPLG+ P W P
Sbjct: 178 LILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPP 237
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L++D L ++ R KT AQ+++R+ I G +VIPKS RI NF + DF L+ E++
Sbjct: 238 LLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMK 297
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
I++ + R V + H +PF +E
Sbjct: 298 DIEALNKNVRFVELLMWRDHPEYPFHDE 325
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 241 bits (591), Expect = 2e-63
Identities = 119/268 (44%), Positives = 162/268 (60%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE EVGEAI KI EG V RED+F KLW T H P++VR L+ TL L + Y+DLY
Sbjct: 58 YQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLY 117
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
+I P A+K ++P D++GK + + TW+AME GLVKS+GVSNFN +QLE
Sbjct: 118 IIEVPMAFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLE 177
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP-WAKPDDPQ 321
+L + KPV NQVECHPY Q +L +FC+ + ITAYSPLG+ P W P
Sbjct: 178 LILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPP 237
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L++D L ++ R KT AQ+++R+ I G +VIPKS RI NF + DF L+ E++
Sbjct: 238 LLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMK 297
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
I++ + R V + H +PF +E
Sbjct: 298 DIEALNKNVRFVELLMWRDHPEYPFHDE 325
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 232 bits (567), Expect = 1e-60
Identities = 130/286 (45%), Positives = 168/286 (58%), Gaps = 21/286 (7%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE+EVG I KIKEG V REDLFI +KLW T H+ LV A +++L L + YLDLY
Sbjct: 40 YHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLY 99
Query: 671 LIHWPQAYKEDGSLF-------------------PTDQSGKIQFSDVDYVDTWKAMEPLV 549
LIHWP +K + P D+S + SD D++DTW+AME LV
Sbjct: 100 LIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLV 159
Query: 548 KEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITA 375
GLVK+IGVSNFN +QLERLL + KP+ NQ+ECHPYL QK L FC++R V +TA
Sbjct: 160 ITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTA 219
Query: 374 YSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSR 195
Y PLG + L+++P +K IA GK+ AQ+LIR+QI IVIP S+T S
Sbjct: 220 YRPLGG------SCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSH 273
Query: 194 IASNFDVLDFKLSREDVALIDSFDCGGRLVPMTASLGHKHHPFENE 57
I N V DF+L++ D+ I S + RL + H +PF E
Sbjct: 274 IKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHNDYPFHIE 319
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 228 bits (557), Expect = 2e-59
Identities = 111/221 (50%), Positives = 147/221 (66%), Gaps = 3/221 (1%)
Frame = -2
Query: 836 EVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 657
EVG AI SKI +G V RED+F TSKLW HRP+LVR AL+ +L NL + Y+DLYLIH+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 656 QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 477
+ K + P D++GKI F VD TW+A+E GL KSIGVSNFN +QLE +L
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 476 ATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQLMEDP 306
+ KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P L+EDP
Sbjct: 146 PGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDP 205
Query: 305 KLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASN 183
L A+A + +T A + +RYQ+ G +V+ KS RI N
Sbjct: 206 VLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQN 246
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 224 bits (548), Expect = 3e-58
Identities = 126/269 (46%), Positives = 162/269 (60%), Gaps = 21/269 (7%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE+EVG I KIKEG V REDLFI +KLW T H+ LV A +++L L + YLDLY
Sbjct: 40 YHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLY 99
Query: 671 LIHWPQAYKEDGSLF-------------------PTDQSGKIQFSDVDYVDTWKAMEPLV 549
LIHWP +K + P D+S + SD D++DTW+AME LV
Sbjct: 100 LIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLV 159
Query: 548 KEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITA 375
GLVK+IGVSNFN +QLERLL + KP+ NQ+ECHPYL QK L FC++R V +TA
Sbjct: 160 ITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTA 219
Query: 374 YSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSR 195
Y PLG + L+++P +K IA GK+ AQ+LIR+QI IVIP S+T S
Sbjct: 220 YRPLG------GSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSH 273
Query: 194 IASNFDVLDFKLSREDVALIDSFDCGGRL 108
I N V DF+L++ D+ I S + RL
Sbjct: 274 IKENIQVFDFELTQHDMDNILSLNRNLRL 302
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 224 bits (548), Expect = 3e-58
Identities = 126/269 (46%), Positives = 162/269 (60%), Gaps = 21/269 (7%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE+EVG I KIKEG V REDLFI +KLW T H+ LV A +++L L + YLDLY
Sbjct: 40 YHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLY 99
Query: 671 LIHWPQAYKEDGSLF-------------------PTDQSGKIQFSDVDYVDTWKAMEPLV 549
LIHWP +K + P D+S + SD D++DTW+AME LV
Sbjct: 100 LIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLV 159
Query: 548 KEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITA 375
GLVK+IGVSNFN +QLERLL + KP+ NQ+ECHPYL QK L FC++R V +TA
Sbjct: 160 ITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTA 219
Query: 374 YSPLGSPDRPWAKPDDPQLMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSR 195
Y PLG + L+++P +K IA GK+ AQ+LIR+QI IVIP S+T S
Sbjct: 220 YRPLG------GSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSH 273
Query: 194 IASNFDVLDFKLSREDVALIDSFDCGGRL 108
I N V DF+L++ D+ I S + RL
Sbjct: 274 IKENIQVFDFELTQHDMDNILSLNRNLRL 302
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 212 bits (517), Expect = 2e-54
Identities = 101/193 (52%), Positives = 133/193 (68%), Gaps = 3/193 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE++VG AI SKI +G V RED+F TSKLW+ HRP+LVR AL+ +L NL + Y+DLY
Sbjct: 68 YNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLY 127
Query: 671 LIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 492
LIH+P + K + P D++GKI F VD TW+AME GL KSIGVSNFN + LE
Sbjct: 128 LIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLE 187
Query: 491 RLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS-PDRPWAKPDDPQ 321
+L + KPV NQVECHPY NQ++L +FC+++ + + AYS LGS + PW P+ P
Sbjct: 188 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 247
Query: 320 LMEDPKLKAIADR 282
L+EDP L A+A +
Sbjct: 248 LLEDPVLCALAKK 260
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 196 bits (477), Expect = 1e-49
Identities = 111/268 (41%), Positives = 152/268 (56%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE+EVG+AI KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL+
Sbjct: 58 YQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLF 117
Query: 671 LIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 495
+IH P A K+ G L P D SG+I V+ DTW+ L K GL
Sbjct: 118 IIHVPFAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGL-------------- 163
Query: 494 ERLLQHATVKPVVNQV-ECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP-WAKPDDPQ 321
KP NQV ECHPYLNQ +L EFC+++ + + AYS LGS P W PD P
Sbjct: 164 -------RYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPH 216
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+E+P LK+IA + ++ QV +RYQ+ G +V+ KS ++ RI NF + DF+L+ ED+
Sbjct: 217 LLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPEDMK 276
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + H + PF E
Sbjct: 277 AIDGLN---RNLRYDNAANHPYFPFSEE 301
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 196 bits (477), Expect = 1e-49
Identities = 111/268 (41%), Positives = 152/268 (56%), Gaps = 3/268 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE+EVG+AI KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL+
Sbjct: 58 YQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLF 117
Query: 671 LIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 495
+IH P A K+ G L P D SG+I V+ DTW+ L K GL
Sbjct: 118 IIHVPFAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGL-------------- 163
Query: 494 ERLLQHATVKPVVNQV-ECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP-WAKPDDPQ 321
KP NQV ECHPYLNQ +L EFC+++ + + AYS LGS P W PD P
Sbjct: 164 -------RYKPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPH 216
Query: 320 LMEDPKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVA 141
L+E+P LK+IA + ++ QV +RYQ+ G +V+ KS ++ RI NF + DF+L+ ED+
Sbjct: 217 LLEEPILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPEDMK 276
Query: 140 LIDSFDCGGRLVPMTASLGHKHHPFENE 57
ID + R + + H + PF E
Sbjct: 277 AIDGLN---RNLRYDNAANHPYFPFSEE 301
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 134 bits (323), Expect = 5e-31
Identities = 76/156 (48%), Positives = 94/156 (60%), Gaps = 21/156 (13%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE+EVG I KIKEG V REDLFI +KLW T H+ LV A +++L L + YLDLY
Sbjct: 40 YHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLY 99
Query: 671 LIHWPQAYKED--------GSL-----------FPTDQSGKIQFSDVDYVDTWKAMEPLV 549
LIHWP +K L P D+S + SD D++DTW+AME LV
Sbjct: 100 LIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLV 159
Query: 548 KEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQV 447
GLVK+IGVSNFN +QLERLL + KP+ NQ+
Sbjct: 160 ITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
Score = 54.4 bits (125), Expect = 5e-07
Identities = 29/69 (42%), Positives = 39/69 (56%)
Frame = -2
Query: 263 QVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCGGRLVPMTASLG 84
Q+LIR+QI IVIP S+T S I N V DF+L++ D+ I S + RL +
Sbjct: 194 QILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKN 253
Query: 83 HKHHPFENE 57
HK +PF E
Sbjct: 254 HKDYPFHIE 262
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 134 bits (323), Expect = 5e-31
Identities = 76/156 (48%), Positives = 94/156 (60%), Gaps = 21/156 (13%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE+EVG I KIKEG V REDLFI +KLW T H+ LV A +++L L + YLDLY
Sbjct: 40 YHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLY 99
Query: 671 LIHWPQAYKED--------GSL-----------FPTDQSGKIQFSDVDYVDTWKAMEPLV 549
LIHWP +K L P D+S + SD D++DTW+AME LV
Sbjct: 100 LIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLV 159
Query: 548 KEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQV 447
GLVK+IGVSNFN +QLERLL + KP+ NQ+
Sbjct: 160 ITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
Score = 44.8 bits (101), Expect = 4e-04
Identities = 24/52 (46%), Positives = 32/52 (61%)
Frame = -2
Query: 263 QVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCGGRL 108
Q+LIR+QI IVIP S+T S I N V DF+L++ D+ I S + RL
Sbjct: 194 QILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRL 245
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 109 bits (262), Expect = 1e-23
Identities = 48/98 (48%), Positives = 67/98 (68%), Gaps = 1/98 (1%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEG-VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDL 675
YGNE E+GEA+ + G V RE+LF+TSKLWNT H P+ V AL++TL +L ++YLDL
Sbjct: 50 YGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDL 109
Query: 674 YLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAM 561
YL+HWP A++ + FP + G I + Y +TWKA+
Sbjct: 110 YLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 107 bits (257), Expect = 5e-23
Identities = 54/122 (44%), Positives = 75/122 (61%), Gaps = 3/122 (2%)
Frame = -2
Query: 653 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 474
A+K ++P D++GK + + TW+AME GLVKS+GVSNFN +QLE +L
Sbjct: 2 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 61
Query: 473 TVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPDRP-WAKPDDPQLMEDPK 303
+K PV NQVECHPY Q +L +FC+ + ITAYSPLG+ P W + L++ P
Sbjct: 62 GLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWRQLHKLALLDLPI 121
Query: 302 LK 297
L+
Sbjct: 122 LR 123
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 89.8 bits (213), Expect = 1e-17
Identities = 50/116 (43%), Positives = 64/116 (55%), Gaps = 19/116 (16%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE+EVG I KIKEG V REDLFI +KLW T H+ LV A +++L L + YLDLY
Sbjct: 40 YHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLY 99
Query: 671 LIHWPQAYKED--------GSL-----------FPTDQSGKIQFSDVDYVDTWKAM 561
LIHWP +K L P D+S + SD D++DTW+ +
Sbjct: 100 LIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEIL 155
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/69 (40%), Positives = 39/69 (56%)
Frame = -2
Query: 263 QVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALIDSFDCGGRLVPMTASLG 84
++LIR+QI IVIP S+T S I N V DF+L++ D+ I S + RL +
Sbjct: 153 EILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKN 212
Query: 83 HKHHPFENE 57
HK +PF E
Sbjct: 213 HKDYPFHIE 221
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 77.4 bits (182), Expect = 6e-14
Identities = 36/69 (52%), Positives = 47/69 (68%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE+EVG+AI KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL+
Sbjct: 58 YQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLF 117
Query: 671 LIHWPQAYK 645
+IH P A K
Sbjct: 118 IIHVPFAMK 126
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 77.4 bits (182), Expect = 6e-14
Identities = 36/69 (52%), Positives = 47/69 (68%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE+EVG+AI KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL+
Sbjct: 58 YQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLF 117
Query: 671 LIHWPQAYK 645
+IH P A K
Sbjct: 118 IIHVPFAMK 126
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 77.4 bits (182), Expect = 6e-14
Identities = 36/69 (52%), Positives = 47/69 (68%)
Frame = -2
Query: 851 YGNEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLY 672
Y NE+EVG+AI KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL+
Sbjct: 58 YQNEEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLF 117
Query: 671 LIHWPQAYK 645
+IH P A K
Sbjct: 118 IIHVPFAMK 126
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 75.4 bits (177), Expect = 2e-13
Identities = 31/63 (49%), Positives = 45/63 (71%)
Frame = -2
Query: 845 NEKEVGEAIXSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLI 666
NE+ +G+AI KI G V R+D+F T+K+W TF RP+LV+ L+ +L L + Y+DLYL
Sbjct: 58 NEEGIGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLF 117
Query: 665 HWP 657
H+P
Sbjct: 118 HFP 120
>AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-related
protein protein.
Length = 85
Score = 73.3 bits (172), Expect = 1e-12
Identities = 41/84 (48%), Positives = 52/84 (61%)
Frame = -2
Query: 308 PKLKAIADRLGKTVAQVLIRYQIDSGNIVIPKSVTRSRIASNFDVLDFKLSREDVALIDS 129
PK+K IA + KT AQVLIR+ I IVIPKSVT +RI N V DFKLS E++A I S
Sbjct: 1 PKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILS 60
Query: 128 FDCGGRLVPMTASLGHKHHPFENE 57
F+ R + S + +PF+ E
Sbjct: 61 FNRNWRACNVLQSSHLEDYPFDAE 84
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 66.1 bits (154), Expect = 2e-10
Identities = 34/63 (53%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Frame = -2
Query: 632 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPV 459
L PTD++GK+ F VD TW+AME GL KSIGVSNFN +QLE +L + KPV
Sbjct: 5 LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPV 64
Query: 458 VNQ 450
NQ
Sbjct: 65 CNQ 67
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 45.2 bits (102), Expect = 3e-04
Identities = 17/35 (48%), Positives = 25/35 (71%)
Frame = -2
Query: 761 LWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 657
+W TF RP+LV+ L+ +L L + Y+DLYL H+P
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFP 35
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.015
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = -2
Query: 572 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 447
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.015
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = -2
Query: 572 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 447
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.015
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = -2
Query: 572 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 447
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.015
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = -2
Query: 572 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 447
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.015
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = -2
Query: 572 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 447
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 39.5 bits (88), Expect = 0.015
Identities = 19/42 (45%), Positives = 27/42 (64%)
Frame = -2
Query: 572 WKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 447
W+ +E LV+ + +IG S+ + QLE+L Q A VKP NQV
Sbjct: 147 WEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQV 188
>BC030254-1|AAH30254.1| 433|Homo sapiens chromosome 20 open reading
frame 160 protein.
Length = 433
Score = 35.1 bits (77), Expect = 0.33
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = -3
Query: 682 WICT*YTGPRPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRV-WSRASESPTST 506
W+C+ PR K ++RP + S + T+ T +W+ SS R+ WSR S +
Sbjct: 352 WLCSRIMAPRTPLKHVTAARP--HLLSMAPTAAAATTA-VWAWSSYRITWSRCGVSWGPS 408
Query: 505 RSSWRGCC 482
RSS CC
Sbjct: 409 RSSSLRCC 416
>AL031658-5|CAI42581.1| 433|Homo sapiens chromosome 20 open reading
frame 160 protein.
Length = 433
Score = 35.1 bits (77), Expect = 0.33
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Frame = -3
Query: 682 WICT*YTGPRPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRV-WSRASESPTST 506
W+C+ PR K ++RP + S + T+ T +W+ SS R+ WSR S +
Sbjct: 352 WLCSRIMAPRTPLKHVTAARP--HLLSMAPTAAAATTA-VWAWSSYRITWSRCGVSWGPS 408
Query: 505 RSSWRGCC 482
RSS CC
Sbjct: 409 RSSSLRCC 416
>BC111958-1|AAI11959.1| 710|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 3 protein.
Length = 710
Score = 33.9 bits (74), Expect = 0.75
Identities = 24/52 (46%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +2
Query: 644 PCRPGASVS-GTDPSTERSDCPGSPAGHRAPSPGDETCSTVSKL*TDLPSLR 796
P P +SVS G+ PS+ RS +PAG SPG + ST L DLPS R
Sbjct: 544 PSSPTSSVSPGSPPSSPRSR--DAPAGSPPASPGPQGPSTKLPLSLDLPSPR 593
>BC101756-1|AAI01757.1| 710|Homo sapiens ral guanine nucleotide
dissociation stimulator-like 3 protein.
Length = 710
Score = 33.9 bits (74), Expect = 0.75
Identities = 24/52 (46%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +2
Query: 644 PCRPGASVS-GTDPSTERSDCPGSPAGHRAPSPGDETCSTVSKL*TDLPSLR 796
P P +SVS G+ PS+ RS +PAG SPG + ST L DLPS R
Sbjct: 544 PSSPTSSVSPGSPPSSPRSR--DAPAGSPPASPGPQGPSTKLPLSLDLPSPR 593
>AK074082-1|BAB84908.1| 497|Homo sapiens FLJ00153 protein protein.
Length = 497
Score = 33.9 bits (74), Expect = 0.75
Identities = 24/52 (46%), Positives = 29/52 (55%), Gaps = 1/52 (1%)
Frame = +2
Query: 644 PCRPGASVS-GTDPSTERSDCPGSPAGHRAPSPGDETCSTVSKL*TDLPSLR 796
P P +SVS G+ PS+ RS +PAG SPG + ST L DLPS R
Sbjct: 341 PSSPTSSVSPGSPPSSPRSR--DAPAGSPPASPGPQGPSTKLPLSLDLPSPR 390
>AB058756-1|BAB47482.1| 708|Homo sapiens KIAA1853 protein protein.
Length = 708
Score = 33.5 bits (73), Expect = 1.00
Identities = 27/73 (36%), Positives = 35/73 (47%)
Frame = -3
Query: 667 YTGPRPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRASESPTSTRSSWRG 488
Y P P+ +LSS + SSSR S + + R WSRS R SR S +S+ S
Sbjct: 616 YYRPSPSSSGSLSSTSSWYSSSSSR-SASRSYSRSWSRSRSRRRSRTRTSSSSSSRSPSP 674
Query: 487 CCSTRLSSRSSIR 449
+R SRS R
Sbjct: 675 GSRSRSRSRSRSR 687
>AJ009794-1|CAA08833.1| 362|Homo sapiens hug-1 protein.
Length = 362
Score = 33.1 bits (72), Expect = 1.3
Identities = 25/92 (27%), Positives = 38/92 (41%)
Frame = -1
Query: 732 GARCPAGDPGQSERSVLGSVPDTLAPGLQGRRLSLPDRPIR*NPVLGRRLRGHLEGYGAA 553
G+R P + ++ L PGL+ RRL RP L R + G A
Sbjct: 204 GSRAPRAARSPRDNGIISGERGRLGPGLRRRRLLPSIRPSAPKERLRRPETSGISDAGGA 263
Query: 552 RQRGSGQEHRSLQLQLEAAGEVAAARDCQAGR 457
R G G+ + S+ A+ + A RD +G+
Sbjct: 264 RVAGPGRPN-SISWAAAASVRLWARRDSSSGQ 294
>Z99716-2|CAI41689.1| 177|Homo sapiens protein ( Human DNA sequence
from clone CTA-250D10 on chromosome 22 Contains the
genes for SREBF2 (sterol regulatory element binding
transcription factosterol regulatory element binding
transcription factor 2).
Length = 177
Score = 31.9 bits (69), Expect = 3.0
Identities = 14/37 (37%), Positives = 19/37 (51%)
Frame = +2
Query: 632 ESRLPCRPGASVSGTDPSTERSDCPGSPAGHRAPSPG 742
E P R S G D ++E + PG+ A H P+PG
Sbjct: 131 EGAQPARAAHSDQGADRASEAAGPPGATASHPGPTPG 167
>AL833963-1|CAD38811.1| 453|Homo sapiens hypothetical protein
protein.
Length = 453
Score = 31.9 bits (69), Expect = 3.0
Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 1/36 (2%)
Frame = +2
Query: 293 WPSVWGPP*AGGRRAWPR-VCPASRGESTL*SSRRE 397
WPS W PP + + W R CP +R + SS R+
Sbjct: 39 WPSSWPPPSSSSWQLWERPSCPTTRAAPLMASSSRK 74
>BX640881-1|CAE45937.1| 999|Homo sapiens hypothetical protein
protein.
Length = 999
Score = 31.1 bits (67), Expect = 5.3
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Frame = -1
Query: 804 GRSR-NEGRSVHNFETVEHVSSPGLGARCPAGDPGQSERSVLGSVPDTLAPGLQGRRLS 631
G+ R + H+ ET E P + PA D ++E S PDTLA +G+ +S
Sbjct: 113 GKKRPRSSAATHSLETQELCEIPAKVIQSPAADTRRAEMSQTNFTPDTLAQN-EGKAMS 170
>AY576779-1|AAT39521.1| 860|Homo sapiens nucleolar protein with
MIF4G domain 1 protein.
Length = 860
Score = 31.1 bits (67), Expect = 5.3
Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 3/65 (4%)
Frame = -1
Query: 393 RREDHSVLSPRLAGQTLGQARRPPA---HGGPQTEGHR*QTREDCRPGPHQIPDRQREHR 223
R+E + R +T G + P G + GHR T E RP P + P R+ R
Sbjct: 86 RKEKRHLRKARRLQRTAGPEQGPGLGGRSGAEEASGHRQDTEERARPAPSRDPSPPRKPR 145
Query: 222 DPEVR 208
V+
Sbjct: 146 PSRVK 150
>AB029007-1|BAA83036.2| 778|Homo sapiens KIAA1084 protein protein.
Length = 778
Score = 31.1 bits (67), Expect = 5.3
Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Frame = -1
Query: 804 GRSR-NEGRSVHNFETVEHVSSPGLGARCPAGDPGQSERSVLGSVPDTLAPGLQGRRLS 631
G+ R + H+ ET E P + PA D ++E S PDTLA +G+ +S
Sbjct: 81 GKKRPRSSAATHSLETQELCEIPAKVIQSPAADTRRAEMSQTNFTPDTLAQN-EGKAMS 138
>U30826-1|AAA93070.1| 272|Homo sapiens SRp40-1 protein.
Length = 272
Score = 30.7 bits (66), Expect = 7.0
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = -3
Query: 655 RPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRA-SESPTSTRSSWRGCCS 479
R +T SSR ++ +S SR S ++ R SRS R SR+ S SP +S RG S
Sbjct: 189 RSRSRTRSSSRSRSRSRSRSRKS--YSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG-SS 245
Query: 478 TRLSSRSSI 452
+R S +S+
Sbjct: 246 SRSKSPASV 254
>BT007089-1|AAP35752.1| 272|Homo sapiens splicing factor,
arginine/serine-rich 5 protein.
Length = 272
Score = 30.7 bits (66), Expect = 7.0
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = -3
Query: 655 RPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRA-SESPTSTRSSWRGCCS 479
R +T SSR ++ +S SR S ++ R SRS R SR+ S SP +S RG S
Sbjct: 189 RSRSRTRSSSRSRSRSRSRSRKS--YSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG-SS 245
Query: 478 TRLSSRSSI 452
+R S +S+
Sbjct: 246 SRSKSPASV 254
>BC040209-1|AAH40209.1| 272|Homo sapiens splicing factor,
arginine/serine-rich 5 protein.
Length = 272
Score = 30.7 bits (66), Expect = 7.0
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = -3
Query: 655 RPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRA-SESPTSTRSSWRGCCS 479
R +T SSR ++ +S SR S ++ R SRS R SR+ S SP +S RG S
Sbjct: 189 RSRSRTRSSSRSRSRSRSRSRKS--YSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG-SS 245
Query: 478 TRLSSRSSI 452
+R S +S+
Sbjct: 246 SRSKSPASV 254
>BC018823-1|AAH18823.1| 272|Homo sapiens splicing factor,
arginine/serine-rich 5 protein.
Length = 272
Score = 30.7 bits (66), Expect = 7.0
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = -3
Query: 655 RPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRA-SESPTSTRSSWRGCCS 479
R +T SSR ++ +S SR S ++ R SRS R SR+ S SP +S RG S
Sbjct: 189 RSRSRTRSSSRSRSRSRSRSRKS--YSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG-SS 245
Query: 478 TRLSSRSSI 452
+R S +S+
Sbjct: 246 SRSKSPASV 254
>AY130006-1|AAN05090.1| 90|Homo sapiens MU-MB-2.76 protein.
Length = 90
Score = 30.7 bits (66), Expect = 7.0
Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 1/71 (1%)
Frame = -3
Query: 658 PRPTRKTALSSRPTNQVKSSSRT-SITWTPGRLWSRSSKRVWSRASESPTSTRSSWRGCC 482
P P+ +LSS + SSSR+ S +++ R SRS +R +R S S +S S
Sbjct: 1 PSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRS 60
Query: 481 STRLSSRSSIR 449
+R SRS R
Sbjct: 61 RSRSRSRSRSR 71
>AB209804-1|BAD93041.1| 326|Homo sapiens CS0DF038YO05 variant
protein.
Length = 326
Score = 30.7 bits (66), Expect = 7.0
Identities = 26/69 (37%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = -3
Query: 655 RPTRKTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRA-SESPTSTRSSWRGCCS 479
R +T SSR ++ +S SR S ++ R SRS R SR+ S SP +S RG S
Sbjct: 243 RSRSRTRSSSRSRSRSRSRSRKS--YSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG-SS 299
Query: 478 TRLSSRSSI 452
+R S +S+
Sbjct: 300 SRSKSPASV 308
>X05562-1|CAA29076.1| 1043|Homo sapiens protein ( Human mRNA for
alpha-2 chain of collagen IV N-terminus. ).
Length = 1043
Score = 30.3 bits (65), Expect = 9.3
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 7/70 (10%)
Frame = -1
Query: 741 PG-LGARCPAGDPGQSE------RSVLGSVPDTLAPGLQGRRLSLPDRPIR*NPVLGRRL 583
PG LG PAG PGQ + R+V G + + PG G LP P P + L
Sbjct: 644 PGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGL 703
Query: 582 RGHLEGYGAA 553
RG + G+ A
Sbjct: 704 RG-IPGFAGA 712
>EF471359-1|ABO86192.1| 270|Homo sapiens MHC class I antigen
protein.
Length = 270
Score = 30.3 bits (65), Expect = 9.3
Identities = 21/70 (30%), Positives = 29/70 (41%)
Frame = -3
Query: 643 KTALSSRPTNQVKSSSRTSITWTPGRLWSRSSKRVWSRASESPTSTRSSWRGCCSTRLSS 464
KT ++ P + +++ R W G + W R E T TRSSWR S
Sbjct: 185 KTHMTHHPISDHEATLRC---WALG-FYPAEITLTWQRDGEDQTHTRSSWRPGLQGMEPS 240
Query: 463 RSSIRWNVIL 434
RS W +L
Sbjct: 241 RSGRLWWCLL 250
>AL162417-13|CAI13418.1| 294|Homo sapiens globoside
alpha-1,3-N-acetylgalactosaminyltransferase 1 protein.
Length = 294
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = -3
Query: 688 STWICT*YTGPRPTRKTALSSR-PTNQVKSSSRTSITWTPGRLWSRSSKRVWS 533
S W+ T ++ P P+R T R P + S+ T + GR W+ SS +W+
Sbjct: 151 SRWVPTGFSAPSPSRVTPTGRRHPCAGWRPSASTLLRGLTGR-WTTSSALMWT 202
>AL161773-3|CAH71366.2| 1712|Homo sapiens collagen type IV alpha 2
protein.
Length = 1712
Score = 30.3 bits (65), Expect = 9.3
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 7/70 (10%)
Frame = -1
Query: 741 PG-LGARCPAGDPGQSE------RSVLGSVPDTLAPGLQGRRLSLPDRPIR*NPVLGRRL 583
PG LG PAG PGQ + R+V G + + PG G LP P P + L
Sbjct: 644 PGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGL 703
Query: 582 RGHLEGYGAA 553
RG + G+ A
Sbjct: 704 RG-IPGFAGA 712
>AL159153-1|CAH72050.2| 1712|Homo sapiens collagen type IV alpha 2
protein.
Length = 1712
Score = 30.3 bits (65), Expect = 9.3
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 7/70 (10%)
Frame = -1
Query: 741 PG-LGARCPAGDPGQSE------RSVLGSVPDTLAPGLQGRRLSLPDRPIR*NPVLGRRL 583
PG LG PAG PGQ + R+V G + + PG G LP P P + L
Sbjct: 644 PGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGL 703
Query: 582 RGHLEGYGAA 553
RG + G+ A
Sbjct: 704 RG-IPGFAGA 712
>AL139385-2|CAI17005.2| 1712|Homo sapiens collagen type IV alpha 2
protein.
Length = 1712
Score = 30.3 bits (65), Expect = 9.3
Identities = 25/70 (35%), Positives = 32/70 (45%), Gaps = 7/70 (10%)
Frame = -1
Query: 741 PG-LGARCPAGDPGQSE------RSVLGSVPDTLAPGLQGRRLSLPDRPIR*NPVLGRRL 583
PG LG PAG PGQ + R+V G + + PG G LP P P + L
Sbjct: 644 PGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGL 703
Query: 582 RGHLEGYGAA 553
RG + G+ A
Sbjct: 704 RG-IPGFAGA 712
>AK074639-1|BAC11106.1| 294|Homo sapiens 40). protein.
Length = 294
Score = 30.3 bits (65), Expect = 9.3
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = -3
Query: 688 STWICT*YTGPRPTRKTALSSR-PTNQVKSSSRTSITWTPGRLWSRSSKRVWS 533
S W+ T ++ P P+R T R P + S+ T + GR W+ SS +W+
Sbjct: 151 SRWVPTGFSAPSPSRVTPTGRRHPCAGWRPSASTLLRGLTGR-WTTSSALMWT 202
>AJ238850-1|CAB52754.1| 1203|Homo sapiens hyperpolarization-activated
channel type 4 protein.
Length = 1203
Score = 30.3 bits (65), Expect = 9.3
Identities = 19/49 (38%), Positives = 23/49 (46%)
Frame = -1
Query: 756 EHVSSPGLGARCPAGDPGQSERSVLGSVPDTLAPGLQGRRLSLPDRPIR 610
EH P +R P+ PGQ LG P L+ GL LS P+ P R
Sbjct: 956 EHFLPPPPSSRSPSSSPGQ-----LGQPPGELSLGLATGPLSTPETPPR 999
>AJ132429-1|CAB42604.1| 1203|Homo sapiens hyperpolarization-activated
cyclic nucleotide gated cation channel hHCN4 protein.
Length = 1203
Score = 30.3 bits (65), Expect = 9.3
Identities = 19/49 (38%), Positives = 23/49 (46%)
Frame = -1
Query: 756 EHVSSPGLGARCPAGDPGQSERSVLGSVPDTLAPGLQGRRLSLPDRPIR 610
EH P +R P+ PGQ LG P L+ GL LS P+ P R
Sbjct: 956 EHFLPPPPSSRSPSSSPGQ-----LGQPPGELSLGLATGPLSTPETPPR 999
>AF117899-1|AAF27280.1| 363|Homo sapiens LDLR-FUT fusion protein
protein.
Length = 363
Score = 30.3 bits (65), Expect = 9.3
Identities = 23/61 (37%), Positives = 29/61 (47%)
Frame = -1
Query: 696 ERSVLGSVPDTLAPGLQGRRLSLPDRPIR*NPVLGRRLRGHLEGYGAARQRGSGQEHRSL 517
ER++ P APG G RLS P PV R EG G +RG G+E RS+
Sbjct: 243 ERTLRKGRPHPAAPGTPGVRLSGPAALPSAQPV-----RTGSEGLGRRGRRGRGRESRSV 297
Query: 516 Q 514
+
Sbjct: 298 R 298
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 121,851,943
Number of Sequences: 237096
Number of extensions: 2851511
Number of successful extensions: 13019
Number of sequences better than 10.0: 128
Number of HSP's better than 10.0 without gapping: 11269
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12823
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10816958492
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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