Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmnc14d09
(810 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P49366 Cluster: Deoxyhypusine synthase; n=40; Eukaryota... 336 4e-91
UniRef50_UPI00015B4ADD Cluster: PREDICTED: similar to deoxyhypus... 332 6e-90
UniRef50_A7SNR4 Cluster: Predicted protein; n=5; Eumetazoa|Rep: ... 324 2e-87
UniRef50_Q9FI94 Cluster: Deoxyhypusine synthase; n=17; Eukaryota... 322 9e-87
UniRef50_Q7QQK3 Cluster: GLP_66_24805_25974; n=1; Giardia lambli... 295 8e-79
UniRef50_P38791 Cluster: Deoxyhypusine synthase; n=57; Eukaryota... 287 2e-76
UniRef50_A7AQ07 Cluster: Deoxyhypusine synthase, putative; n=1; ... 284 2e-75
UniRef50_UPI0000498E3F Cluster: deoxyhypusine synthase; n=1; Ent... 234 2e-60
UniRef50_Q8SQN2 Cluster: Deoxyhypusine synthase; n=1; Encephalit... 219 9e-56
UniRef50_P49366-2 Cluster: Isoform Short of P49366 ; n=21; Eutel... 204 3e-51
UniRef50_O50105 Cluster: Probable deoxyhypusine synthase; n=31; ... 198 1e-49
UniRef50_UPI0000499BAB Cluster: deoxyhypusine synthase; n=1; Ent... 188 1e-46
UniRef50_Q014Q0 Cluster: Deoxyhypusine synthase; n=1; Ostreococc... 186 8e-46
UniRef50_Q0KHM1 Cluster: Deoxyhypusine synthase; n=5; Plasmodium... 171 2e-41
UniRef50_Q9GSW0 Cluster: Deoxyhypusine synthase; n=2; Plasmodium... 166 5e-40
UniRef50_Q4QD19 Cluster: Deoxyhypusine synthase, putative; n=5; ... 161 2e-38
UniRef50_Q9HPX2 Cluster: Probable deoxyhypusine synthase; n=2; H... 161 2e-38
UniRef50_Q9HL74 Cluster: Probable deoxyhypusine synthase; n=6; A... 158 1e-37
UniRef50_Q12UX5 Cluster: Deoxyhypusine synthase; n=1; Methanococ... 148 1e-34
UniRef50_Q4CSD9 Cluster: Deoxyhypusine synthase, putative; n=3; ... 143 4e-33
UniRef50_A4YHK6 Cluster: Deoxyhypusine synthase; n=1; Metallosph... 135 1e-30
UniRef50_A7DSG5 Cluster: Deoxyhypusine synthase; n=1; Candidatus... 131 2e-29
UniRef50_Q97ZF1 Cluster: Probable deoxyhypusine synthase; n=7; T... 131 2e-29
UniRef50_A0RUJ9 Cluster: Deoxyhypusine synthase; n=1; Cenarchaeu... 113 5e-24
UniRef50_Q5CHK2 Cluster: Deoxyhypusine synthase; n=1; Cryptospor... 111 2e-23
UniRef50_A1RX92 Cluster: Deoxyhypusine synthase; n=1; Thermofilu... 108 2e-22
UniRef50_Q8ZT09 Cluster: Probable deoxyhypusine synthase; n=5; T... 107 4e-22
UniRef50_Q0J1Q0 Cluster: Os09g0421100 protein; n=5; Oryza sativa... 105 1e-21
UniRef50_Q4Q3H5 Cluster: Deoxyhypusine synthase, putative; n=3; ... 105 2e-21
UniRef50_Q8MPC1 Cluster: Putative dexyhypusine synthase; n=1; Ta... 93 6e-18
UniRef50_O26230 Cluster: Probable deoxyhypusine synthase; n=3; M... 82 2e-14
UniRef50_UPI000065F1C0 Cluster: Deoxyhypusine synthase (EC 2.5.1... 81 2e-14
UniRef50_Q18GE0 Cluster: Deoxyhypusine synthase; n=3; Halobacter... 77 5e-13
UniRef50_Q8PV89 Cluster: Probable deoxyhypusine synthase 1; n=10... 77 7e-13
UniRef50_O28088 Cluster: Probable deoxyhypusine synthase 1; n=1;... 76 9e-13
UniRef50_Q8Q051 Cluster: Probable deoxyhypusine synthase 2; n=8;... 67 4e-10
UniRef50_Q8TXD7 Cluster: Probable deoxyhypusine synthase; n=1; M... 66 7e-10
UniRef50_A7H9T8 Cluster: Deoxyhypusine synthase; n=2; Bacteria|R... 64 4e-09
UniRef50_A0B8D8 Cluster: Deoxyhypusine synthase; n=1; Methanosae... 62 2e-08
UniRef50_A3DLU9 Cluster: Deoxyhypusine synthase; n=1; Staphyloth... 55 2e-06
UniRef50_O50106 Cluster: Putative uncharacterized protein PH1398... 53 1e-05
UniRef50_Q9AB72 Cluster: Deoxyhypusine synthase-like protein; n=... 50 7e-05
UniRef50_Q8DKP1 Cluster: Deoxyhypusine synthase-like protein; n=... 47 5e-04
UniRef50_A6C8I9 Cluster: Deoxyhypusine synthase; n=1; Planctomyc... 46 0.001
UniRef50_A0RU78 Cluster: Deoxyhypusine synthase; n=5; Crenarchae... 42 0.024
UniRef50_Q2JJ35 Cluster: Deoxyhypusine synthase family protein; ... 38 0.23
UniRef50_Q5ACN0 Cluster: Putative uncharacterized protein; n=1; ... 38 0.30
UniRef50_Q20103 Cluster: Putative uncharacterized protein; n=3; ... 37 0.69
UniRef50_A0LN06 Cluster: Deoxyhypusine synthase; n=1; Syntrophob... 36 1.2
UniRef50_Q09A08 Cluster: Deoxyhypusine synthase; n=3; Cystobacte... 35 2.8
UniRef50_Q029V5 Cluster: Deoxyhypusine synthase; n=1; Solibacter... 33 6.4
UniRef50_Q6FZT4 Cluster: Branched chain aa ABC transporter, peri... 33 8.5
UniRef50_A0UWX0 Cluster: Extracellular solute-binding protein, f... 33 8.5
>UniRef50_P49366 Cluster: Deoxyhypusine synthase; n=40;
Eukaryota|Rep: Deoxyhypusine synthase - Homo sapiens
(Human)
Length = 369
Score = 336 bits (826), Expect = 4e-91
Identities = 151/229 (65%), Positives = 184/229 (80%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VTTAGG+EEDLIKC+APTY+G+F+L GK LR GINRIGNLLVPN+NYC FE+W+ P+LD
Sbjct: 129 VTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFEDWLMPILD 188
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFH 364
+M+ EQ EG W+PS++ ARLG+ INN SV YWA +N+IP+FSPALTDGSLGDM++FH
Sbjct: 189 QMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFH 248
Query: 363 SFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVNT 184
S+K P +NT A+ A TG+ +KHHI NANLMRNGADYAVY+NT
Sbjct: 249 SYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGADYAVYINT 308
Query: 183 ASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVAQTFAK 37
A EFDGSD+GARPDEAVSWGKIR +A PVK+YADA+LVFPL+VA+TFA+
Sbjct: 309 AQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQ 357
>UniRef50_UPI00015B4ADD Cluster: PREDICTED: similar to deoxyhypusine
synthase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to deoxyhypusine synthase - Nasonia vitripennis
Length = 521
Score = 332 bits (816), Expect = 6e-90
Identities = 149/222 (67%), Positives = 181/222 (81%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VTTAGG+EED IKC+APTYVGDF+L GK LR +GINRIGNLLVPNDNYCLFE+WV P+LD
Sbjct: 249 VTTAGGVEEDFIKCLAPTYVGDFHLDGKTLRDKGINRIGNLLVPNDNYCLFEDWVMPILD 308
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFH 364
+M+ EQ K+G +W+PS++ ARLGE INN S+ YWA +N IP+FSPALTDGSLGDMMYFH
Sbjct: 309 KMLEEQ-KKGVLWTPSKVIARLGEEINNRDSIYYWAAKNKIPVFSPALTDGSLGDMMYFH 367
Query: 363 SFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVNT 184
SFK P LNT+A+KA +GV +KHHICNANLMRNGAD+ V++NT
Sbjct: 368 SFKNPGLVVDIVSDLRRLNTIAMKAIRSGVIIIGGGVVKHHICNANLMRNGADFGVFLNT 427
Query: 183 ASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLI 58
ASE+DGSD+GARPDEAVSWGKIR ++ VK++A+A+LVFPL+
Sbjct: 428 ASEYDGSDSGARPDEAVSWGKIRKDSKAVKIFAEASLVFPLL 469
>UniRef50_A7SNR4 Cluster: Predicted protein; n=5; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 366
Score = 324 bits (796), Expect = 2e-87
Identities = 139/234 (59%), Positives = 184/234 (78%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VTT GGIEED +KC+AP+Y+GDF++SG+ LR +GINRIGNLLVPNDNYC E+++ P+LD
Sbjct: 129 VTTGGGIEEDFMKCLAPSYLGDFSISGEFLRKKGINRIGNLLVPNDNYCKLEDFIQPVLD 188
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFH 364
+M+ EQ EG W+PS+ ARLG+ IN+ SV YWA++NNIP+FSPA+TDG++GD +YFH
Sbjct: 189 KMLEEQQNEGINWTPSKFIARLGKEINHPESVYYWAYKNNIPVFSPAITDGAIGDAIYFH 248
Query: 363 SFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVNT 184
S++ P +N AV + NTG+ +KHH+CNAN+MRNGADYAVYVNT
Sbjct: 249 SYRNPGLKLDIAEDVRLVNNHAVFSKNTGIIILGGGLVKHHVCNANMMRNGADYAVYVNT 308
Query: 183 ASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVAQTFAKHHFSS 22
A EFDGSD+GARPDEAVSWGKI+ A PVK+Y +++L+FPL+VA+TFA++ S+
Sbjct: 309 AQEFDGSDSGARPDEAVSWGKIKATATPVKIYGESSLIFPLLVAETFARNFKST 362
>UniRef50_Q9FI94 Cluster: Deoxyhypusine synthase; n=17;
Eukaryota|Rep: Deoxyhypusine synthase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 368
Score = 322 bits (790), Expect = 9e-87
Identities = 143/230 (62%), Positives = 176/230 (76%), Gaps = 2/230 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VTT GG+EEDLIKC+APT+ GDF+L G LR++G+NRIGNLLVPNDNYC FE+W+ P+ D
Sbjct: 128 VTTTGGVEEDLIKCLAPTFKGDFSLPGAYLRSKGLNRIGNLLVPNDNYCKFEDWIIPIFD 187
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFH 364
EM+ EQ +E +W+PS++ ARLG+ INNESS YWA++ NIP+F P LTDGSLGDM+YFH
Sbjct: 188 EMLKEQKEENVLWTPSKLLARLGKEINNESSYLYWAYKMNIPVFCPGLTDGSLGDMLYFH 247
Query: 363 SFKRPXXXXXXXXXXXXLNTMAVKAN--NTGVXXXXXXXIKHHICNANLMRNGADYAVYV 190
SF+ +N AV AN TG+ KHHICNAN+MRNGADYAV++
Sbjct: 248 SFRTSGLIIDVVQDIRAMNGEAVHANPKKTGMIILGGGLPKHHICNANMMRNGADYAVFI 307
Query: 189 NTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVAQTFA 40
NT EFDGSD+GARPDEAVSWGKIR +A VK+Y DAT+ FPL+VA+TFA
Sbjct: 308 NTGQEFDGSDSGARPDEAVSWGKIRGSAKTVKVYCDATIAFPLLVAETFA 357
>UniRef50_Q7QQK3 Cluster: GLP_66_24805_25974; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_66_24805_25974 - Giardia lamblia
ATCC 50803
Length = 389
Score = 295 bits (724), Expect = 8e-79
Identities = 135/232 (58%), Positives = 170/232 (73%), Gaps = 1/232 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VT+AGG+EED+IKC+APTY+GD+ G +LR INRIGNLLVPNDNYCLFE+W+ P+ D
Sbjct: 126 VTSAGGVEEDIIKCLAPTYLGDWKTDGAMLRKNSINRIGNLLVPNDNYCLFEDWIIPIFD 185
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFH 364
E + EQ ++G W+PSR+ +LG+RIN+E S+ YWA+RN IPIF PA+TDGSLGDM++FH
Sbjct: 186 ECV-EQQRKGYHWTPSRLIWKLGKRINDERSIAYWAYRNKIPIFCPAITDGSLGDMLFFH 244
Query: 363 SFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMR-NGADYAVYVN 187
S+K P +N A+ + G IKHHI NANL +GAD+AVY+N
Sbjct: 245 SYKNPGLIIDVVGDIRAMNMQAINSPKNGCIILGSGTIKHHILNANLFAGDGADFAVYIN 304
Query: 186 TASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVAQTFAKHH 31
TA E+DGSDAGA DEAVSWGKI P A PVKL ADATLVFPL++ +T K +
Sbjct: 305 TAQEYDGSDAGATCDEAVSWGKISPTARPVKLCADATLVFPLLLHETILKKY 356
>UniRef50_P38791 Cluster: Deoxyhypusine synthase; n=57;
Eukaryota|Rep: Deoxyhypusine synthase - Saccharomyces
cerevisiae (Baker's yeast)
Length = 387
Score = 287 bits (705), Expect = 2e-76
Identities = 141/246 (57%), Positives = 172/246 (69%), Gaps = 18/246 (7%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VT+AGG+EEDLIKC+APTY+G+F L GK LR +G+NRIGNLLVPNDNYC FEEW+ P+LD
Sbjct: 132 VTSAGGVEEDLIKCLAPTYLGEFALKGKSLRDQGMNRIGNLLVPNDNYCKFEEWIVPILD 191
Query: 543 EMISEQ----MKEGT------------VWSPSRITARLGERINNESSVCYWAWRNNIPIF 412
+M+ EQ K G +W+PS++ R G+ IN+ESSV YWA +N IPIF
Sbjct: 192 KMLEEQDEYVKKHGADCLEANQDVDSPIWTPSKMIDRFGKEINDESSVLYWAHKNKIPIF 251
Query: 411 SPALTDGSLGDMMYFHSFKRPXXXXXXXXXXXXL--NTMAVKANNTGVXXXXXXXIKHHI 238
P+LTDGS+GDM++FH+FK N+M++ A G+ IKHHI
Sbjct: 252 CPSLTDGSIGDMLFFHTFKASPKQLRVDIVGDIRKINSMSMAAYRAGMIILGGGLIKHHI 311
Query: 237 CNANLMRNGADYAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLI 58
NA LMRNGADYAVY+NT E+DGSDAGARPDEAVSWGKI+ A VKL+AD T V PLI
Sbjct: 312 ANACLMRNGADYAVYINTGQEYDGSDAGARPDEAVSWGKIKAEAKSVKLFADVTTVLPLI 371
Query: 57 VAQTFA 40
VA TFA
Sbjct: 372 VAATFA 377
>UniRef50_A7AQ07 Cluster: Deoxyhypusine synthase, putative; n=1;
Babesia bovis|Rep: Deoxyhypusine synthase, putative -
Babesia bovis
Length = 370
Score = 284 bits (697), Expect = 2e-75
Identities = 124/233 (53%), Positives = 164/233 (70%), Gaps = 3/233 (1%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VT+ GG+EEDLIKC+ TY+G FN+ G +R G+NRIGNL +PNDNYC FE W+ P LD
Sbjct: 133 VTSGGGVEEDLIKCMGKTYIGRFNMDGATMRESGLNRIGNLFIPNDNYCDFETWLQPRLD 192
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFH 364
EM +Q ++G W+PS LG+ IN+E+S CYW +N IP+F P +TDGS+GD +YFH
Sbjct: 193 EMHRQQTEDGVSWTPSTFIDFLGKEINDETSFCYWCHKNQIPVFCPGITDGSIGDNLYFH 252
Query: 363 SFKR---PXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVY 193
++ + +N +AV + +G+ KHH+CNANLMRNGAD+AVY
Sbjct: 253 TYSKSSPTTLKIDVVRDIRRVNDIAVHSKKSGIIILGGGLAKHHVCNANLMRNGADFAVY 312
Query: 192 VNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVAQTFAKH 34
++TA EFDGSD+GA PDEAVSWGKI+ NPVK++ADA+LVFPL+VA F K+
Sbjct: 313 ISTAQEFDGSDSGANPDEAVSWGKIKAYTNPVKVHADASLVFPLLVAGVFRKY 365
>UniRef50_UPI0000498E3F Cluster: deoxyhypusine synthase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: deoxyhypusine
synthase - Entamoeba histolytica HM-1:IMSS
Length = 336
Score = 234 bits (572), Expect = 2e-60
Identities = 111/235 (47%), Positives = 145/235 (61%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
V TAGGIEED IK + PT +GDF GK L G NRIGNL++PN NYC FE+W+ PLL
Sbjct: 102 VVTAGGIEEDFIKTMHPTLLGDFYFKGKELYPNGYNRIGNLILPNSNYCEFEDWMDPLLL 161
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFH 364
E + EQ + G W+PS++ ++GE INNESS+ YWA +NNIP+FSPA+TDGS+GDM++F
Sbjct: 162 ECLKEQNEHGVHWTPSKLVHKMGESINNESSIYYWAAKNNIPVFSPAITDGSIGDMIFFF 221
Query: 363 SFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVNT 184
S+K ++ MA A G KHHI NA R G DY ++T
Sbjct: 222 SYKNEGLVLDLVQDVIKIDEMAFNAEKVGCLLVGAGIAKHHILNAMKRRGGCDYCAMLST 281
Query: 183 ASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVAQTFAKHHFSSK 19
+ E D SDAG+ + G +P NP K+ DAT++ PLIVA TFA+ +K
Sbjct: 282 SIECDASDAGSEIAADRTKGFFKPECNPAKVIGDATILLPLIVASTFAQKEEPTK 336
>UniRef50_Q8SQN2 Cluster: Deoxyhypusine synthase; n=1;
Encephalitozoon cuniculi|Rep: Deoxyhypusine synthase -
Encephalitozoon cuniculi
Length = 362
Score = 219 bits (534), Expect = 9e-56
Identities = 103/230 (44%), Positives = 144/230 (62%), Gaps = 1/230 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
V T GGIEED+IK PT+ DF L G LR G+NRIGNL++P++NY E W+ +++
Sbjct: 125 VITGGGIEEDIIKAFKPTFCADFRLDGAELRDNGLNRIGNLVIPSENYEHLESWLNNIVN 184
Query: 543 EMISEQMKEGT-VWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYF 367
++ E + +PS LGERI++ESS+ YWA +N+IP++SPA+ DGSLGD++ F
Sbjct: 185 DITEGYTAERPRILTPSSFIRILGERIDDESSILYWAAKNDIPVYSPAVVDGSLGDILSF 244
Query: 366 HSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVN 187
H +R +N + T +KHHI NANL +NG ++ V +N
Sbjct: 245 HP-RRKMLKLDIVEDVYRINCETIFCGETAAIILGCGVVKHHILNANLFKNGLEHCVLIN 303
Query: 186 TASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVAQTFAK 37
A EFDGSDAGA DEAVSWGK++P VK++ DAT++FPL+V TF +
Sbjct: 304 NAQEFDGSDAGASLDEAVSWGKVKPGTRGVKVFGDATILFPLLVGATFMR 353
>UniRef50_P49366-2 Cluster: Isoform Short of P49366 ; n=21;
Euteleostomi|Rep: Isoform Short of P49366 - Homo sapiens
(Human)
Length = 322
Score = 204 bits (497), Expect = 3e-51
Identities = 86/125 (68%), Positives = 107/125 (85%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VTTAGG+EEDLIKC+APTY+G+F+L GK LR GINRIGNLLVPN+NYC FE+W+ P+LD
Sbjct: 129 VTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFEDWLMPILD 188
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFH 364
+M+ EQ EG W+PS++ ARLG+ INN SV YWA +N+IP+FSPALTDGSLGDM++FH
Sbjct: 189 QMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGSLGDMIFFH 248
Query: 363 SFKRP 349
S+K P
Sbjct: 249 SYKNP 253
Score = 88.2 bits (209), Expect = 2e-16
Identities = 39/49 (79%), Positives = 46/49 (93%)
Frame = -1
Query: 183 ASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVAQTFAK 37
A EFDGSD+GARPDEAVSWGKIR +A PVK+YADA+LVFPL+VA+TFA+
Sbjct: 262 AQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQ 310
>UniRef50_O50105 Cluster: Probable deoxyhypusine synthase; n=31;
Euryarchaeota|Rep: Probable deoxyhypusine synthase -
Pyrococcus horikoshii
Length = 342
Score = 198 bits (483), Expect = 1e-49
Identities = 99/231 (42%), Positives = 139/231 (60%), Gaps = 8/231 (3%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VTTAGG+EED IK + P +GD+ + LR +G+NRIGN+ VPND Y FE+++ P +
Sbjct: 99 VTTAGGVEEDFIKSLKPFILGDWEVDDAELRKKGVNRIGNIFVPNDRYIEFEKYMIPFFE 158
Query: 543 EMISEQMKEGTVWSPSRITARLGERINN------ESSVCYWAWRNNIPIFSPALTDGSLG 382
++ + K + S +G ++ E SV YWA++NNIPIF PA+TDGS+G
Sbjct: 159 RVLKIEEKLSRPLTASEFIYEMGRYMDEKLGKEKEKSVIYWAYKNNIPIFCPAITDGSIG 218
Query: 381 DMMYFHSFKR--PXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGA 208
DM+YF +R LN +A+ A T KH I NANL R G
Sbjct: 219 DMLYFFKEERRDSRLIIDIANDIVKLNNLAITAKETASIILGGSLPKHAIINANLFRGGT 278
Query: 207 DYAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIV 55
DYA+Y++TA +DGS +GA P E VSWGKI+ A+ V+++ DATL+FP++V
Sbjct: 279 DYAIYISTAVPWDGSLSGAPPREGVSWGKIKAKADYVEVWGDATLIFPILV 329
>UniRef50_UPI0000499BAB Cluster: deoxyhypusine synthase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: deoxyhypusine
synthase - Entamoeba histolytica HM-1:IMSS
Length = 331
Score = 188 bits (458), Expect = 1e-46
Identities = 100/229 (43%), Positives = 141/229 (61%), Gaps = 1/229 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VTTAG IE D++KC +GDF + K +G R GN+++P + ++W+ +
Sbjct: 98 VTTAGAIETDIMKCFGNMNIGDFYM--KPEEVQG-ERHGNMIIPKELIEKTKQWLKEFIL 154
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMY-F 367
+ I E ++PS++ +GER+N+ +SV WA +NNI IF PALTDG G +
Sbjct: 155 D-IQECQDTSMPFTPSQLITMMGERLNDTTSVITWAAKNNITIFCPALTDGLFGTCITEL 213
Query: 366 HSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVN 187
+ +N+ + + TGV +KHHI NANLMRNGAD+AVY+N
Sbjct: 214 NEINPVRLMVDLVQDLRLINSSTIHSVETGVIILGGGVMKHHIMNANLMRNGADFAVYIN 273
Query: 186 TASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVAQTFA 40
TA +FDGSDA ARPDEAVSWGKI+ ++ VK+ A+A+LVFPLIV++TFA
Sbjct: 274 TAGDFDGSDASARPDEAVSWGKIKIDSENVKVLAEASLVFPLIVSKTFA 322
>UniRef50_Q014Q0 Cluster: Deoxyhypusine synthase; n=1; Ostreococcus
tauri|Rep: Deoxyhypusine synthase - Ostreococcus tauri
Length = 495
Score = 186 bits (452), Expect = 8e-46
Identities = 77/124 (62%), Positives = 100/124 (80%)
Frame = -1
Query: 720 TTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLDE 541
TTAGG+EED IKC+ PTY+GDF L G+ LR +G+NRIGNL+ PNDNYC FE+W+ P+LDE
Sbjct: 368 TTAGGVEEDFIKCMKPTYLGDFALRGEDLRKKGLNRIGNLIQPNDNYCDFEDWIMPILDE 427
Query: 540 MISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFHS 361
M+ EQ +EG W+ S++ RLG IN+E S+ YWA +N+IP + PALTDGS+GDM+YFHS
Sbjct: 428 MLREQNEEGVKWTCSKVIKRLGLEINHEDSIFYWAAKNDIPCYCPALTDGSIGDMLYFHS 487
Query: 360 FKRP 349
+K P
Sbjct: 488 YKNP 491
>UniRef50_Q0KHM1 Cluster: Deoxyhypusine synthase; n=5;
Plasmodium|Rep: Deoxyhypusine synthase - Plasmodium
vivax
Length = 455
Score = 171 bits (415), Expect = 2e-41
Identities = 80/169 (47%), Positives = 110/169 (65%), Gaps = 5/169 (2%)
Frame = -1
Query: 504 SPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFHSFKRPXXXXXXXX 325
SPS +LGE IN+ESS+ YW +N+IP+F P LTDGSLGD ++FH++ +
Sbjct: 280 SPSEFIDKLGEEINDESSLIYWCHKNDIPVFCPGLTDGSLGDNLFFHNYGKKIKNNLILD 339
Query: 324 XXXXL---NTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVNTASEFDGSDAG 154
+ N++A+ +G+ KHH+CNANLMRNGAD+AVYVNTA+E+DGSD+G
Sbjct: 340 IVKDIKKINSLALNCKKSGIIILGGGLPKHHVCNANLMRNGADFAVYVNTANEYDGSDSG 399
Query: 153 ARPDEAVSWGKIRP--NANPVKLYADATLVFPLIVAQTFAKHHFSSKKN 13
A EA+SWGKI+ N VK++ DAT++FPL+V TF H + N
Sbjct: 400 ANTTEALSWGKIKAGHTNNHVKVFGDATILFPLMVLNTFYLHDRGGRHN 448
Score = 112 bits (269), Expect = 1e-23
Identities = 50/82 (60%), Positives = 67/82 (81%)
Frame = -1
Query: 762 VFLVKK*ALWM*FVTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDN 583
V+L KK + + VTTAGG+EED+IKC + TY+GDFNL+GK LR +G NRIGNL+VPNDN
Sbjct: 145 VYLAKKKFIDV-VVTTAGGVEEDIIKCFSKTYLGDFNLNGKKLRKKGWNRIGNLIVPNDN 203
Query: 582 YCLFEEWVTPLLDEMISEQMKE 517
YC FE+W+ PLL++M+ EQ ++
Sbjct: 204 YCKFEDWLQPLLNKMLHEQNRK 225
>UniRef50_Q9GSW0 Cluster: Deoxyhypusine synthase; n=2; Plasmodium
falciparum|Rep: Deoxyhypusine synthase - Plasmodium
falciparum
Length = 496
Score = 166 bits (404), Expect = 5e-40
Identities = 79/170 (46%), Positives = 111/170 (65%), Gaps = 5/170 (2%)
Frame = -1
Query: 504 SPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFHSFKRPXXXXXXXX 325
SPS LG+ IN+ESS+ YW ++N+IPIF P LTDGSLGD ++ H++ +
Sbjct: 327 SPSEFINTLGKEINDESSLIYWCYKNDIPIFCPGLTDGSLGDNLFLHNYGKKIKNNLILD 386
Query: 324 XXXXL---NTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVNTASEFDGSDAG 154
+ N++A+ +G+ KHH+CNANLMRNGAD+AVYVNTASE+DGSD+G
Sbjct: 387 IVKDIKKINSLAMNCEKSGIIILGGGLPKHHVCNANLMRNGADFAVYVNTASEYDGSDSG 446
Query: 153 ARPDEAVSWGKIR--PNANPVKLYADATLVFPLIVAQTFAKHHFSSKKNV 10
A EA+SWGKI+ N VK++ DAT++FPL+V +F + KK++
Sbjct: 447 ANTTEALSWGKIKYGQTNNHVKVFGDATILFPLMVLNSFYLYDQKRKKDM 496
Score = 112 bits (270), Expect = 9e-24
Identities = 49/90 (54%), Positives = 68/90 (75%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VTTAGGIEED+IKC + TY+GDFNL+GK LR +G NRIGNL+VPNDNYC FE+W+ P+L+
Sbjct: 168 VTTAGGIEEDIIKCFSNTYIGDFNLNGKKLRKKGWNRIGNLIVPNDNYCKFEDWLQPILN 227
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNES 454
+M+ EQ ++ ++ R + NN++
Sbjct: 228 KMLHEQNEKNEQMFLKKLEKRKKKYNNNKN 257
>UniRef50_Q4QD19 Cluster: Deoxyhypusine synthase, putative; n=5;
Trypanosomatidae|Rep: Deoxyhypusine synthase, putative -
Leishmania major
Length = 379
Score = 161 bits (391), Expect = 2e-38
Identities = 94/234 (40%), Positives = 127/234 (54%), Gaps = 10/234 (4%)
Frame = -1
Query: 726 FVTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLL 547
F+++AGGIEED+IKC T +G F L G+ LR RGINRIGNLLVPNDNYC FE++ TP+L
Sbjct: 138 FISSAGGIEEDVIKCGGSTLLGQFGLDGRALRRRGINRIGNLLVPNDNYCWFEDFFTPVL 197
Query: 546 DEMISEQ--MKEGTVWSPSRITARLGERINNE------SSVCYWAWRNNIPIFSPALTDG 391
+ + Q + T +PS +G I SS+ YW +RN I +FSPA TDG
Sbjct: 198 ESVQEAQRASRWKTHTAPSEFIEAMGAAIAKNHPDTCTSSLVYWCYRNGISVFSPAFTDG 257
Query: 390 SLGDMMYFHSFKRPXXXXXXXXXXXXLNTMAVKANNTGV-XXXXXXXIKHHICNANLMRN 214
S+GDM+YF++F L +A K + KHH L+RN
Sbjct: 258 SMGDMIYFYNFSHKGLVVDPLEDVVRLRKLAAKEKGRNLAIVLGGGLPKHH-----LLRN 312
Query: 213 -GADYAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIV 55
D V V T E DG + + V+ G +R V++ DAT+VFPL++
Sbjct: 313 VSMDAVVMVTTGLEADGCVSSGVLADDVACGLLREETETVRVQGDATVVFPLML 366
>UniRef50_Q9HPX2 Cluster: Probable deoxyhypusine synthase; n=2;
Halobacteriaceae|Rep: Probable deoxyhypusine synthase -
Halobacterium salinarium (Halobacterium halobium)
Length = 330
Score = 161 bits (391), Expect = 2e-38
Identities = 88/233 (37%), Positives = 134/233 (57%), Gaps = 6/233 (2%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
+TT+G + ED+IK P +G++++ LR GINR+GN+ VP+D Y EE++ +
Sbjct: 101 ITTSGSLTEDIIKTAKPFKMGEWDVDEAALREEGINRLGNIFVPSDRYVWLEEYLYDFFE 160
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFH 364
E ++Q V +P+ LG +++E S+ A N+IP+F PALTD +G+ +Y+
Sbjct: 161 EFFADQK----VRTPTAFARELGATLDDEDSILKNAADNDIPVFCPALTDAEIGNFLYY- 215
Query: 363 SFKRPXXXXXXXXXXXXLNTM---AVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVY 193
+++ + + + A+ TG+ KHH NL R GADYAVY
Sbjct: 216 -YRQGYDSEVGIEILDDYDALIEEGLLADTTGLICVGAGVPKHHAIMTNLFRGGADYAVY 274
Query: 192 VNTASEFDGSDAGARPDEAVSWGKIR-PNANP--VKLYADATLVFPLIVAQTF 43
++T E DGS +GA P+EAVSWGKI+ +A P + A+ATLVFPL+VA F
Sbjct: 275 ISTGMEGDGSLSGAPPEEAVSWGKIKDEDAEPNYALIEAEATLVFPLLVAGAF 327
>UniRef50_Q9HL74 Cluster: Probable deoxyhypusine synthase; n=6;
Archaea|Rep: Probable deoxyhypusine synthase -
Thermoplasma acidophilum
Length = 310
Score = 158 bits (384), Expect = 1e-37
Identities = 85/225 (37%), Positives = 131/225 (58%), Gaps = 1/225 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYC-LFEEWVTPLL 547
+TT+G ++ D+ + Y G F+ S LR GINR+GN+LVP+++Y + EE V L
Sbjct: 87 ITTSGTLDHDIARTYRNYYCGSFSYSDIELRDLGINRLGNVLVPDESYGEIIEEKVMESL 146
Query: 546 DEMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYF 367
+++ +++ KE W+ + +G IN+ESS+ Y A +NNIP+F P +TDGS G ++
Sbjct: 147 EKLYAKK-KE---WATVDLIHEVGLDINSESSIIYNAAKNNIPVFVPGITDGSFGSQLWS 202
Query: 366 HSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVN 187
+ L+ + A TG KHH N R+G DYAVYV
Sbjct: 203 FYEQHHDFKINLLEDEHRLSDIIFDAKKTGAIMIGGGISKHHTIWWNQFRDGLDYAVYVT 262
Query: 186 TASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVA 52
TA E+DGS +GA+ +EA+SW K+RP+A V +Y DAT++ P+++A
Sbjct: 263 TAQEYDGSLSGAKLEEAISWKKVRPDARYVNVYGDATVIMPVLLA 307
>UniRef50_Q12UX5 Cluster: Deoxyhypusine synthase; n=1;
Methanococcoides burtonii DSM 6242|Rep: Deoxyhypusine
synthase - Methanococcoides burtonii (strain DSM 6242)
Length = 324
Score = 148 bits (359), Expect = 1e-34
Identities = 76/222 (34%), Positives = 120/222 (54%), Gaps = 1/222 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTY-VGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLL 547
VTT GG+EED++K + +G F+ L +GINR+GNLL+ ++Y FE V +L
Sbjct: 79 VTTVGGLEEDIMKATGEDFQIGSFHTDDVELHEQGINRVGNLLIKTESYMNFESLVDKIL 138
Query: 546 DEMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYF 367
E+ +Q + W+ S + +G +++ESS+ Y A +NN+PIF PA+TDG+ G +Y
Sbjct: 139 KELYEKQNR----WAVSDMLREIGLMLDDESSILYQAAKNNVPIFCPAITDGAFGFHLYL 194
Query: 366 HSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVN 187
+ P + + + GV KHH + L+ GA+YAVY+
Sbjct: 195 FQQEHPDFIVDVVKDFGNILFASSHDDRKGVIALGGSISKHHAILSTLLNGGAEYAVYMT 254
Query: 186 TASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPL 61
TA GS +GA +EA SWGK++ ++ + D ++ FPL
Sbjct: 255 TAHRTSGSMSGANTNEAKSWGKVKDESDVATVIGDVSITFPL 296
>UniRef50_Q4CSD9 Cluster: Deoxyhypusine synthase, putative; n=3;
Trypanosoma|Rep: Deoxyhypusine synthase, putative -
Trypanosoma cruzi
Length = 469
Score = 143 bits (347), Expect = 4e-33
Identities = 73/170 (42%), Positives = 101/170 (59%), Gaps = 1/170 (0%)
Frame = -1
Query: 549 LDEMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMY 370
L E+ +E ++E + + + R ES+V YWA N +PIFSP+ +DG + +
Sbjct: 283 LPELFTEVLRERSGGNMEAVADEAQRRA--ESTVLYWASMNGVPIFSPSFSDGDIMKFIL 340
Query: 369 -FHSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVY 193
LN A+++ +G+ +KHH+CNANLMRNGAD AV+
Sbjct: 341 DTEDLTTALLKLDLVVDIYRLNKFAMRSQRSGMIILGGGVVKHHVCNANLMRNGADGAVF 400
Query: 192 VNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVAQTF 43
+N EFDGSD+GARPDEAVSWGKIR + VK+YA+ +LVFPL+VAQ F
Sbjct: 401 INNGQEFDGSDSGARPDEAVSWGKIRLDGESVKVYAEVSLVFPLLVAQVF 450
>UniRef50_A4YHK6 Cluster: Deoxyhypusine synthase; n=1;
Metallosphaera sedula DSM 5348|Rep: Deoxyhypusine
synthase - Metallosphaera sedula DSM 5348
Length = 310
Score = 135 bits (327), Expect = 1e-30
Identities = 77/224 (34%), Positives = 113/224 (50%), Gaps = 2/224 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYV-GDFNLSGKVLRTRGINRIGNLLVPNDNYC-LFEEWVTPL 550
VTT G I+ D+ + Y G F S + LR ++R+GN+L+P ++Y + E V +
Sbjct: 86 VTTGGTIDHDIARSFGGKYYKGSFEFSDEELRKINVHRLGNILIPFEDYGGMVENAVNRI 145
Query: 549 LDEMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMY 370
L ++ E+ + WS + G+RI ++ S+ A+ N PI P + DGS G ++
Sbjct: 146 LPPLVKEKRE----WSVYELLWEFGKRIEDKHSILRAAYETNTPIIVPGVVDGSFGTNLF 201
Query: 369 FHSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYV 190
S + + + G KHH N R+G DYAVY+
Sbjct: 202 IQS-QFTGLRINLFEDMRLIKDRVFSSKMAGALLIGGGISKHHTIWWNQFRDGLDYAVYL 260
Query: 189 NTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLI 58
TA EFDGS +GARP EA+SW KIR NA +YADATL P++
Sbjct: 261 TTAQEFDGSLSGARPREAISWNKIRENAEQAVIYADATLALPIL 304
>UniRef50_A7DSG5 Cluster: Deoxyhypusine synthase; n=1; Candidatus
Nitrosopumilus maritimus SCM1|Rep: Deoxyhypusine
synthase - Candidatus Nitrosopumilus maritimus SCM1
Length = 313
Score = 131 bits (316), Expect = 2e-29
Identities = 75/230 (32%), Positives = 113/230 (49%), Gaps = 1/230 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYC-LFEEWVTPLL 547
+TT G ++ D+ + + G F + L + I+R+GN+LVP D+Y L EE + L
Sbjct: 85 ITTCGALDHDIARHFSHYKEGSFTMDDNELADQDIHRLGNVLVPMDSYGPLIEEKMQTFL 144
Query: 546 DEMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYF 367
+E +KE T + I +G+ + E S YWA++N+I + P + DG++G ++
Sbjct: 145 EEEYQNGVKEMTT---AEICKMIGKHLG-EDSFLYWAYKNHISVVVPGIMDGAVGSQIWL 200
Query: 366 HSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVN 187
+ K L+ KA +G KHH N R G DYA Y+
Sbjct: 201 FTQKHNDFKLNMAGDADLLSGYIFKAEKSGAFMIGGGISKHHTLWWNQYREGLDYAFYIT 260
Query: 186 TASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVAQTFAK 37
TA EFDGS +GA EA+SWGK+ A L+A+ T + P I A K
Sbjct: 261 TAQEFDGSLSGALVREAISWGKVTQKAKQSTLHAEVTTILPFIYAALVTK 310
>UniRef50_Q97ZF1 Cluster: Probable deoxyhypusine synthase; n=7;
Thermoprotei|Rep: Probable deoxyhypusine synthase -
Sulfolobus solfataricus
Length = 312
Score = 131 bits (316), Expect = 2e-29
Identities = 74/226 (32%), Positives = 121/226 (53%), Gaps = 2/226 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYV-GDFNLSGKVLRTRGINRIGNLLVPNDNYC-LFEEWVTPL 550
VTT G I+ DL + Y G F++ +L+ I+R+GN+LVP ++Y + E+ V
Sbjct: 88 VTTGGTIDHDLARSFGGVYYKGSFDIDDTMLKDLEIHRLGNVLVPFESYGKVIEDVVRKF 147
Query: 549 LDEMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMY 370
L E I++ KE + + + G+RI + +S+ A+ N+PI P + DGS G ++
Sbjct: 148 LPE-ITKDRKEISAYE---LLWEFGKRITDSNSILRAAYDKNVPIIVPGILDGSFGTNLF 203
Query: 369 FHSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYV 190
S + + + + +G KHH N ++G +YA+Y+
Sbjct: 204 IQS-QFLNFRINLFEDMRLIKDLIFSSKKSGALIIGGGISKHHTIWWNQFKDGLNYAIYI 262
Query: 189 NTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVA 52
TA E+DGS +GA+P EA+SW KIRP+A V +Y DAT++ P++ A
Sbjct: 263 TTAQEYDGSLSGAKPREAISWNKIRPDAKHVTIYGDATIIVPILAA 308
>UniRef50_A0RUJ9 Cluster: Deoxyhypusine synthase; n=1; Cenarchaeum
symbiosum|Rep: Deoxyhypusine synthase - Cenarchaeum
symbiosum
Length = 312
Score = 113 bits (272), Expect = 5e-24
Identities = 73/225 (32%), Positives = 108/225 (48%), Gaps = 1/225 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYC-LFEEWVTPLL 547
VTT G ++ D+ + + G F + L G++R+G++LVP ++Y L E + L
Sbjct: 85 VTTCGALDHDIARSYSEYREGSFTMDDSELVGAGMHRLGSVLVPLESYGPLIERKMQAFL 144
Query: 546 DEMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYF 367
+E E K S + IT +G E S + A + IP+ P + DG++G ++
Sbjct: 145 EE---EYAKGTRRMSTADITRMIGLH-TGEDSFLHKAAGHGIPVVVPGIMDGAVGSQIWM 200
Query: 366 HSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVN 187
+ K L+ + KA +G KHH N R G DYA+Y+
Sbjct: 201 FTQKHSDFVLDVSADSELLSGLVFKAERSGALMLGGGISKHHTLWWNQYRGGLDYALYMA 260
Query: 186 TASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVA 52
TA E DGS +GA EA+SWGK+ P A V L A+ T V P I A
Sbjct: 261 TADEHDGSLSGAPVREAISWGKVAPGARQVTLRAEITSVLPFIYA 305
>UniRef50_Q5CHK2 Cluster: Deoxyhypusine synthase; n=1;
Cryptosporidium hominis|Rep: Deoxyhypusine synthase -
Cryptosporidium hominis
Length = 244
Score = 111 bits (267), Expect = 2e-23
Identities = 49/86 (56%), Positives = 63/86 (73%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
VT+AGGIEED IK + T++G+FNL G LR +G NRIGNLLVPN NY FEEW+ PL D
Sbjct: 133 VTSAGGIEEDFIKVLGSTFLGEFNLKGSELRNKGWNRIGNLLVPNQNYVDFEEWIQPLFD 192
Query: 543 EMISEQMKEGTVWSPSRITARLGERI 466
EM+ Q K+ W+PS++ LGE++
Sbjct: 193 EMLEMQNKDSINWTPSKMIHFLGEKL 218
>UniRef50_A1RX92 Cluster: Deoxyhypusine synthase; n=1; Thermofilum
pendens Hrk 5|Rep: Deoxyhypusine synthase - Thermofilum
pendens (strain Hrk 5)
Length = 328
Score = 108 bits (259), Expect = 2e-22
Identities = 71/230 (30%), Positives = 108/230 (46%), Gaps = 7/230 (3%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTY-VGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLL 547
VTT G + D+ + Y VG F + L+ GI+R+GN+L+P +NY E T
Sbjct: 92 VTTGGTFDHDIARGTGHKYYVGRFEIDDVFLKELGIHRLGNILIPVENYGPPIERFT--- 148
Query: 546 DEMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGD-MMY 370
EM+ E + WSPS + G+R+ +E S+ + + SP + D + G ++
Sbjct: 149 HEMLEELSALKSSWSPSELAVESGKRLRDELSILRAVYEKGRLLVSPGVLDSAFGTAIVT 208
Query: 369 FHSFKRPXXXXXXXXXXXXLNTMAV-----KANNTGVXXXXXXXIKHHICNANLMRNGAD 205
F+ R + + +A KHH+ R G D
Sbjct: 209 FNDKARASSTARFVELDLISDERRIADYMYEAEKLAGLMLGGGISKHHLIWWAQFRGGLD 268
Query: 204 YAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIV 55
YAV + + E+DGS +GAR EAVSWGKI+P A V + D T++ PLI+
Sbjct: 269 YAVQITSTPEWDGSLSGARTREAVSWGKIKPEARHVTVPGDVTVILPLIL 318
>UniRef50_Q8ZT09 Cluster: Probable deoxyhypusine synthase; n=5;
Thermoproteaceae|Rep: Probable deoxyhypusine synthase -
Pyrobaculum aerophilum
Length = 292
Score = 107 bits (256), Expect = 4e-22
Identities = 68/233 (29%), Positives = 114/233 (48%), Gaps = 10/233 (4%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYV-GDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLL 547
VTTAG ++ D+ K + Y G F+L L +G +R+GN+++ + Y PL+
Sbjct: 66 VTTAGALDHDIAKSMGAVYAPGSFDLDDVDLAAKGYHRLGNVVIKKEEY-------GPLV 118
Query: 546 DEMISEQMKEGTVWSPSRITARLGERINNE---SSVCYWAWRNNIPIFSPALTDGSLGD- 379
++ I ++ +W + T L + E S+ A R +F P + DG++G
Sbjct: 119 EKFILAHCEK--LWGKTLATYELAYLLGAELPEDSILGAAARAGAKVFVPGIVDGAVGTA 176
Query: 378 MMYFHSFKRPXXXXXXXXXXXXLNTMAVK-----ANNTGVXXXXXXXIKHHICNANLMRN 214
+M + R + ++ + KHH+ +
Sbjct: 177 LMTCNDLARTKRGGSRAFIDVLKDEEELREIVHNSKKLAALIVGGGISKHHVIWWAQFKG 236
Query: 213 GADYAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIV 55
G DY VY++TA E+DGS +GARP EA+SWGK++P+A V ++ADATLV P+++
Sbjct: 237 GLDYVVYISTAVEYDGSLSGARPREAISWGKVKPSAKSVFIFADATLVLPVLL 289
>UniRef50_Q0J1Q0 Cluster: Os09g0421100 protein; n=5; Oryza
sativa|Rep: Os09g0421100 protein - Oryza sativa subsp.
japonica (Rice)
Length = 309
Score = 105 bits (253), Expect = 1e-21
Identities = 44/58 (75%), Positives = 52/58 (89%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPL 550
VTTAGGIEEDLIKC+APTY GDF+L G +LR++G+NRIGNLLVPNDNYC FE W+ P+
Sbjct: 143 VTTAGGIEEDLIKCLAPTYRGDFSLPGTLLRSKGLNRIGNLLVPNDNYCKFENWIMPI 200
Score = 101 bits (243), Expect = 2e-20
Identities = 43/63 (68%), Positives = 51/63 (80%)
Frame = -1
Query: 282 TGVXXXXXXXIKHHICNANLMRNGADYAVYVNTASEFDGSDAGARPDEAVSWGKIRPNAN 103
TG+ KHHICNAN+ RNGAD+AVY+NTA EFDGSD+GA+PDEAVSWGKI+ +A
Sbjct: 228 TGIIVLGGGLPKHHICNANMFRNGADFAVYINTAQEFDGSDSGAQPDEAVSWGKIKGSAK 287
Query: 102 PVK 94
PVK
Sbjct: 288 PVK 290
>UniRef50_Q4Q3H5 Cluster: Deoxyhypusine synthase, putative; n=3;
Leishmania|Rep: Deoxyhypusine synthase, putative -
Leishmania major
Length = 601
Score = 105 bits (251), Expect = 2e-21
Identities = 44/89 (49%), Positives = 61/89 (68%)
Frame = -1
Query: 309 NTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVNTASEFDGSDAGARPDEAVS 130
N +A+ + TG+ +KHH+CNANLMRNGAD+ + +N EFDGSDAGA+P+EA+S
Sbjct: 473 NKLAMLSKKTGMLICGGGVVKHHVCNANLMRNGADFTIILNNGQEFDGSDAGAKPEEALS 532
Query: 129 WGKIRPNANPVKLYADATLVFPLIVAQTF 43
WGK+R VK+Y + + PL+VA F
Sbjct: 533 WGKVRMEGAFVKVYGEVSTYLPLLVADVF 561
>UniRef50_Q8MPC1 Cluster: Putative dexyhypusine synthase; n=1;
Taenia solium|Rep: Putative dexyhypusine synthase -
Taenia solium (Pork tapeworm)
Length = 221
Score = 93.5 bits (222), Expect = 6e-18
Identities = 41/75 (54%), Positives = 53/75 (70%), Gaps = 1/75 (1%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNL-SGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLL 547
VT+AGG+EED +KC+A YVGDF+ +G LR GINR GNLLVPN+NY + EEW+ P+
Sbjct: 147 VTSAGGVEEDFVKCMANFYVGDFSRWTGAELRKLGINRTGNLLVPNNNYVILEEWLNPIF 206
Query: 546 DEMISEQMKEGTVWS 502
D M+ EQ W+
Sbjct: 207 DRMLEEQNTNNVNWT 221
>UniRef50_O26230 Cluster: Probable deoxyhypusine synthase; n=3;
Methanobacteriaceae|Rep: Probable deoxyhypusine synthase
- Methanobacterium thermoautotrophicum
Length = 307
Score = 81.8 bits (193), Expect = 2e-14
Identities = 52/224 (23%), Positives = 99/224 (44%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLD 544
+T+ + DL++ + D+ + L GI RIG++ ++++ +FE +
Sbjct: 83 ITSGANLTHDLLEAFGGAHYRDYGFDDEKLHQEGIGRIGDVYTRSEDFEVFESENQEIFS 142
Query: 543 EMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFH 364
+ S + S + +G ++++ S+ A +PI++P L D LG ++ +
Sbjct: 143 SIFSAKPHI----SIQELIHEIGGHLDDDMSIIRTAHLRGVPIYAPGLIDSMLGLQLWMY 198
Query: 363 SFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVNT 184
+ + L+ + G KH+ + L+R G D AV +
Sbjct: 199 T-QDNRICLDAVKDMHSLSDLVFSHERIGAIILGGGLPKHYTLASTLLRGGVDAAVQITM 257
Query: 183 ASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVA 52
GS +GA +EA SW K + +N V + DAT +FP+I+A
Sbjct: 258 DRSETGSLSGAPLEEAKSWAKAQAGSNLVTVVGDATALFPVILA 301
>UniRef50_UPI000065F1C0 Cluster: Deoxyhypusine synthase (EC
2.5.1.46) (DHS).; n=1; Takifugu rubripes|Rep:
Deoxyhypusine synthase (EC 2.5.1.46) (DHS). - Takifugu
rubripes
Length = 163
Score = 81.4 bits (192), Expect = 2e-14
Identities = 30/56 (53%), Positives = 44/56 (78%)
Frame = -1
Query: 516 GTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFHSFKRP 349
G W+PS++ R G+ IN+ SVCYWA++N+IP+FSPALTDG++GD++Y S + P
Sbjct: 1 GVHWTPSKVIQRFGKEINHPESVCYWAYKNDIPVFSPALTDGAIGDVLYLFSVENP 56
Score = 72.1 bits (169), Expect = 2e-11
Identities = 30/43 (69%), Positives = 38/43 (88%)
Frame = -1
Query: 222 MRNGADYAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVK 94
++ GAD+AVYVNTA E DGSD+GA+PDEAV+WGKI+ +A PVK
Sbjct: 121 LKKGADFAVYVNTAQEADGSDSGAKPDEAVTWGKIKMDAKPVK 163
>UniRef50_Q18GE0 Cluster: Deoxyhypusine synthase; n=3;
Halobacteriaceae|Rep: Deoxyhypusine synthase -
Haloquadratum walsbyi (strain DSM 16790)
Length = 374
Score = 77.0 bits (181), Expect = 5e-13
Identities = 55/200 (27%), Positives = 91/200 (45%), Gaps = 5/200 (2%)
Frame = -1
Query: 636 LRTRGINRIGNLLVPNDNYCLFE----EWVTPLLDEMISEQMKEGTVWSPSRITARLGER 469
LR G++RI N+ +P +++ L E E V P ++ IS Q + + +
Sbjct: 164 LREEGVDRIYNVYLPQEHFALLETHLRENVFPAVERQISIQELTAEL-GRANAEKNTQDD 222
Query: 468 INNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFHSFKRPXXXXXXXXXXXXLNTMAVKA 289
I+ + + A+ +++PI+ PA+ D LG + +S + L+ A A
Sbjct: 223 IDEDPGIAAAAYNHDVPIYCPAIQDSVLGIQAWVYS-QTSSFSLDALDDMTHLSDRAFDA 281
Query: 288 NNTGVXXXXXXXIKHHICNANLMRNGA-DYAVYVNTASEFDGSDAGARPDEAVSWGKIRP 112
G K+++ L GA DY V + + G +GA DEA SWGK+ P
Sbjct: 282 ERAGAVVVGGGVPKNYVLQTMLTIPGAYDYGVQLTMDPDATGGLSGATLDEARSWGKLEP 341
Query: 111 NANPVKLYADATLVFPLIVA 52
+A + DAT+ PL+VA
Sbjct: 342 SAANATVLGDATITLPLLVA 361
>UniRef50_Q8PV89 Cluster: Probable deoxyhypusine synthase 1; n=10;
Euryarchaeota|Rep: Probable deoxyhypusine synthase 1 -
Methanosarcina mazei (Methanosarcina frisia)
Length = 317
Score = 76.6 bits (180), Expect = 7e-13
Identities = 55/226 (24%), Positives = 104/226 (46%), Gaps = 2/226 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIA-PTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLL 547
VTT + D ++ + Y G + LR I+RI ++ +P+ ++ EE++ +
Sbjct: 90 VTTGANMVHDTVEALGLHHYKGSDCANDIQLRHECIDRIYDVYLPDQHFTDLEEFLQGVY 149
Query: 546 DEMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYF 367
+ E + S ++ +G+ ++++SS+ A +P++ PAL D +G +
Sbjct: 150 SGLPQENL------SIRQVLTEIGKNLDDDSSILKTAAEMGVPVYCPALQDSVIGLQAWL 203
Query: 366 HSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMR-NGADYAVYV 190
+ P ++ + A + G K++I + L+ DYA+ +
Sbjct: 204 YKEGNPLHVDAFADMHEFMD-ICYGAESAGTMLLGGGVPKNYILQSMLVTPRSFDYAIQL 262
Query: 189 NTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVA 52
G +GA DEA SWGK+ +A V +YAD+T+ PLIV+
Sbjct: 263 TMDRPETGGLSGATLDEAQSWGKVGEDAKSVTVYADSTITLPLIVS 308
>UniRef50_O28088 Cluster: Probable deoxyhypusine synthase 1; n=1;
Archaeoglobus fulgidus|Rep: Probable deoxyhypusine
synthase 1 - Archaeoglobus fulgidus
Length = 301
Score = 76.2 bits (179), Expect = 9e-13
Identities = 58/225 (25%), Positives = 100/225 (44%), Gaps = 1/225 (0%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTY-VGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLL 547
VTT I ++++ + + +G + L INRI ++ V + + EE+++ ++
Sbjct: 78 VTTGANIVHEIVESLGIGHEIGSCYVDDTALAEESINRIYDVFVGQEAFERVEEFLSGII 137
Query: 546 DEMISEQMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYF 367
+ + +G +++ +G+RI +E S A IP+F P L D G M
Sbjct: 138 EGL------DG-IYTTYEFLWEVGKRIPDERSFLRIAAEREIPVFCPTLHDSIAGLHMTI 190
Query: 366 HSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMRNGADYAVYVN 187
+ R + + GV K+ A L+ G DYAV +
Sbjct: 191 Y---RKNLQIDFFRDVSRIIDFCFQKRKMGVIVVGGGVPKNFTLQAMLLAEGFDYAVQIT 247
Query: 186 TASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVA 52
T S G +GA +EA SW K++P+A V +Y DAT+ P++ A
Sbjct: 248 TDSPQWGGLSGATLEEAKSWCKLKPDAKAVTVYCDATIALPMLYA 292
>UniRef50_Q8Q051 Cluster: Probable deoxyhypusine synthase 2; n=8;
Euryarchaeota|Rep: Probable deoxyhypusine synthase 2 -
Methanosarcina mazei (Methanosarcina frisia)
Length = 345
Score = 67.3 bits (157), Expect = 4e-10
Identities = 53/213 (24%), Positives = 96/213 (45%), Gaps = 9/213 (4%)
Frame = -1
Query: 669 YVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLDEM--ISEQMKEGTVWSPS 496
YVG + + L G++RI ++ + + + + +E+ IS +E ++
Sbjct: 105 YVGSHLANDEKLFEHGVDRIYDVFAVEEEFRNADNLIADFAEEIGEISCSSRE-FMYLLG 163
Query: 495 RITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDMMYFHSFKRPXXXXXXXXXXX 316
+ R G E S+ A+R+N+PIF PAL+D S+G + +
Sbjct: 164 KELVRRGAA---EDSIVVSAYRHNVPIFVPALSDSSIGIGLTIARRRGLKLEIDQIKDVD 220
Query: 315 XLNTMAVKANNTGVXXXXXXXIKHHICNANLMRN-------GADYAVYVNTASEFDGSDA 157
+ + K+ +TGV K+ I ++ + G +YA+ + S G +
Sbjct: 221 EITQIVEKSGHTGVVYVGGGVPKNFIQQTEVIASILGMDVPGHEYAIQYTSDSPHWGGLS 280
Query: 156 GARPDEAVSWGKIRPNANPVKLYADATLVFPLI 58
G DEAVSWGK+ A V+++ DAT+ P++
Sbjct: 281 GCTFDEAVSWGKVAAQAKKVQVFVDATIALPIV 313
>UniRef50_Q8TXD7 Cluster: Probable deoxyhypusine synthase; n=1;
Methanopyrus kandleri|Rep: Probable deoxyhypusine
synthase - Methanopyrus kandleri
Length = 297
Score = 66.5 bits (155), Expect = 7e-10
Identities = 45/191 (23%), Positives = 80/191 (41%)
Frame = -1
Query: 624 GINRIGNLLVPNDNYCLFEEWVTPLLDEMISEQMKEGTVWSPSRITARLGERINNESSVC 445
G R+ + +P + + FE ++ +L ++ +W +G+R+ ES
Sbjct: 108 GYGRVHDTHIPTEAFEKFEHFMREVLSDLSGRVSCRELLWE-------MGKRL--ESGFL 158
Query: 444 YWAWRNNIPIFSPALTDGSLGDMMYFHSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXX 265
A +PI+SP + D +G ++ HS + + +A G
Sbjct: 159 RAAADEGVPIYSPGILDSMVGLHVWIHSQDHDFHLDLVDDMHHLAD-LVFEAEELGAIIL 217
Query: 264 XXXXIKHHICNANLMRNGADYAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYA 85
KH A ++R G DYAV + GS +GA +E SW K+R +A +
Sbjct: 218 GGSVPKHFAMGAAMLRGGLDYAVQITMDRPETGSLSGAPLEEGKSWEKVREDAEVATIVG 277
Query: 84 DATLVFPLIVA 52
D ++FPL+ +
Sbjct: 278 DYLIIFPLLAS 288
>UniRef50_A7H9T8 Cluster: Deoxyhypusine synthase; n=2; Bacteria|Rep:
Deoxyhypusine synthase - Anaeromyxobacter sp. Fw109-5
Length = 390
Score = 64.1 bits (149), Expect = 4e-09
Identities = 56/244 (22%), Positives = 105/244 (43%), Gaps = 16/244 (6%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIA-PTYVGDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLL 547
+ T + DL + P G F++ K L GI RI ++ + D+ + +V L
Sbjct: 94 IATGANLYHDLHFALKLPVVQGHFHVDDKELYQAGIERIYDVFITEDSLLDTDAFVREAL 153
Query: 546 DEMISEQMKEGTVWSPSRITARLGERINNESSVCYWAW-----RNNIPIFSPALTDGSLG 382
++ + + G + +P ++ LG+ +N ++ + +W R ++PIF+ + D S+G
Sbjct: 154 EK--APKSLRGHISTP-QLHHYLGQLVNQQAPLPEKSWVATAARYDVPIFTSSPGDSSIG 210
Query: 381 DMMYFHSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNA--------N 226
+ + + A GV K+ +
Sbjct: 211 MNVAAMKLRGGETTVDPDLDVLQSTAIVYDAKVNGVVILGGGSPKNFYLQTQPTLWQILD 270
Query: 225 LMRNGADYAVYVNTASEFDGSDAGARPDEAVSWGKIRPN--ANPVKLYADATLVFPLIVA 52
L R G +Y + ++T S G +GA P EA+SWGK++ N N V +Y+D T+ P++ +
Sbjct: 271 LNRGGHEYVLQISTDSPQWGGLSGATPSEAISWGKVQANMMKNHVVVYSDTTIAAPVVFS 330
Query: 51 QTFA 40
A
Sbjct: 331 YALA 334
>UniRef50_A0B8D8 Cluster: Deoxyhypusine synthase; n=1; Methanosaeta
thermophila PT|Rep: Deoxyhypusine synthase -
Methanosaeta thermophila (strain DSM 6194 / PT)
(Methanothrixthermophila (strain DSM 6194 / PT))
Length = 339
Score = 61.7 bits (143), Expect = 2e-08
Identities = 47/174 (27%), Positives = 78/174 (44%), Gaps = 10/174 (5%)
Frame = -1
Query: 546 DEMISE---QMKEGTVWSPSRITARLGERINNESSVCYWAWRNNIPIFSPALTDGSLGDM 376
D+ IS+ ++ ++S I LG + E+++ A+R +PIF PAL+D S+G
Sbjct: 137 DKYISDLVMSLRTDIMYSSREIMELLGRELP-ETTILGAAYRAGVPIFVPALSDSSIGIG 195
Query: 375 MYFHSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLM-------R 217
M + ++ K+ TGV K+ I ++ R
Sbjct: 196 MVIAWRNGHRVIVDQIRDVDEITQISEKSAETGVVFIGGGVPKNFIQQTKVISELMGTYR 255
Query: 216 NGADYAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIV 55
G YA+ T + G +G EAVSWGK+ A ++++DAT+ PL+V
Sbjct: 256 GGHSYAIQYTTDTPHFGGLSGCTFSEAVSWGKVDKEARMAQVFSDATITVPLVV 309
>UniRef50_A3DLU9 Cluster: Deoxyhypusine synthase; n=1;
Staphylothermus marinus F1|Rep: Deoxyhypusine synthase -
Staphylothermus marinus (strain ATCC 43588 / DSM 3639 /
F1)
Length = 348
Score = 54.8 bits (126), Expect = 2e-06
Identities = 53/239 (22%), Positives = 94/239 (39%), Gaps = 16/239 (6%)
Frame = -1
Query: 723 VTTAGGIEEDLIKCIAPTYV-GDFNLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLL 547
++T I ED+ + + Y G + VL I+R ++ Y E+ L+
Sbjct: 90 ISTGANISEDIYEAMGNYYYKGSPMVDDSVLFKLKIDRFYDVYADELKYREMED----LI 145
Query: 546 DEMISEQMKEGTVWSPSRITARLGERINNESSVCYW--AWRNNIPIFSPALTDGSLGDMM 373
E I E + +S G+ ++ + C A+R+ +P+FSPA+ D G
Sbjct: 146 REFI-ETLDNNKTYSTMEFLYLFGKYLDEKGIDCIVSAAYRSGVPVFSPAIVDSGYGIAS 204
Query: 372 YFHSFKRPXXXXXXXXXXXXLNTMAVKANNTGVXXXXXXXIKHHICNANLMR-------- 217
+ + + ++N K + +M+
Sbjct: 205 ILAKRRGHSIVLDMVKDFEQIVEIGQRSNKLSAIYIGGGVPKDYANLVTVMQMLLAEQEG 264
Query: 216 -----NGADYAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIV 55
G +Y + + T + G +GA +EA+SWGK++ NA +Y DAT+ PLIV
Sbjct: 265 IGDYNKGFEYIIQITTDAPQWGGLSGATLEEAISWGKVKSNAKRRTVYVDATIALPLIV 323
>UniRef50_O50106 Cluster: Putative uncharacterized protein PH1398;
n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized
protein PH1398 - Pyrococcus horikoshii
Length = 111
Score = 52.8 bits (121), Expect = 1e-05
Identities = 32/67 (47%), Positives = 39/67 (58%), Gaps = 2/67 (2%)
Frame = +2
Query: 530 SEIIS--SNNGVTHSSNKQ*LSFGTNKLPILFIPRVLNTFPLKLKSPT*VGAMHFIKSSS 703
S I+S S G+ + SN LSFGT PILF P L++ +SP G F+KSSS
Sbjct: 20 SSILSTLSKKGIMYFSNSIYLSFGTKMFPILFTPFFLSSASSTSQSPRMKGFNDFMKSSS 79
Query: 704 IPPAVVT 724
PPAVVT
Sbjct: 80 TPPAVVT 86
>UniRef50_Q9AB72 Cluster: Deoxyhypusine synthase-like protein; n=27;
Bacteria|Rep: Deoxyhypusine synthase-like protein -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 367
Score = 50.0 bits (114), Expect = 7e-05
Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 13/152 (8%)
Frame = -1
Query: 459 ESSVCYWAWRNNIPIFSPALTDGSLGDMMYFH-----SFKRPXXXXXXXXXXXXLNTMAV 295
E S+ A+ +PIF PA D S G + H + K+P L + +
Sbjct: 199 EGSLIQTAYEEGVPIFCPAFVDSSAGFGLVKHQKEKIAEKKPYLMIDAVADFRELTDVKI 258
Query: 294 KANNTGVXXXXXXXIKHH-----ICNANLMRNGAD---YAVYVNTASEFDGSDAGARPDE 139
A TG+ K+ +C A ++ AD YA+ + A DG+ + + E
Sbjct: 259 AAGTTGLFMVGGGVPKNFAQDTVVC-AEILGVEADMHKYAIQITVADVRDGACSSSTLKE 317
Query: 138 AVSWGKIRPNANPVKLYADATLVFPLIVAQTF 43
A SWGK+ + ++A+AT V PLI + +
Sbjct: 318 AASWGKVSTTYEQM-VFAEATTVVPLIASDAY 348
>UniRef50_Q8DKP1 Cluster: Deoxyhypusine synthase-like protein; n=6;
Cyanobacteria|Rep: Deoxyhypusine synthase-like protein -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 401
Score = 47.2 bits (107), Expect = 5e-04
Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Frame = -1
Query: 225 LMRNGADYAVYVNTASEFDGSDAGARPDEAVSWGKIRPNA--NPVKLYADATLVFPLIVA 52
L G DY + + A G +GA P EAVSWGK+ P + V Y D+T+ P++ A
Sbjct: 283 LEERGHDYFIQITDARPDTGGLSGAVPSEAVSWGKVDPQGLRDTVVCYTDSTIALPILTA 342
>UniRef50_A6C8I9 Cluster: Deoxyhypusine synthase; n=1; Planctomyces
maris DSM 8797|Rep: Deoxyhypusine synthase -
Planctomyces maris DSM 8797
Length = 362
Score = 46.0 bits (104), Expect = 0.001
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 3/94 (3%)
Frame = -1
Query: 654 NLSGKVLRTRGINRIGNLLVPNDNYCLFEEWVTPLLDEMISEQMKEGTVWSPSRITARLG 475
N S + L +G NRI + L N E L+ ++ E E VWS +R+ LG
Sbjct: 118 NDSDETLYKKGYNRIYDTLEMESNLNNVER----LVRSVLRESKPEDGVWSSARLCRALG 173
Query: 474 ER---INNESSVCYWAWRNNIPIFSPALTDGSLG 382
+R ++ + A+ N+P+F PA TD +G
Sbjct: 174 QRLSEVDEGRGILRSAYEQNVPVFIPAFTDSEIG 207
Score = 34.3 bits (75), Expect = 3.7
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Frame = -1
Query: 168 GSDAGARPDEAVSWGK-IRPNANP--VKLYADATLVFPLIVAQTFAK 37
G +G E VSWGK I P ++Y+DAT+V PL++ F K
Sbjct: 311 GGLSGCTYSEGVSWGKFISPQEGGRFAEVYSDATVVLPLLMKAVFEK 357
>UniRef50_A0RU78 Cluster: Deoxyhypusine synthase; n=5;
Crenarchaeota|Rep: Deoxyhypusine synthase - Cenarchaeum
symbiosum
Length = 353
Score = 41.5 bits (93), Expect = 0.024
Identities = 20/53 (37%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = -1
Query: 213 GADYAVYVNTASEFDGSDAGARPDEAVSWGKIR-PNANPVKLYADATLVFPLI 58
G DY + V A G +GA E SWGK++ + V +Y+DAT+ FP++
Sbjct: 247 GQDYIIQVTDARPDTGGLSGATLQEGKSWGKVQDAHEGMVTVYSDATIAFPIM 299
>UniRef50_Q2JJ35 Cluster: Deoxyhypusine synthase family protein;
n=28; Bacteria|Rep: Deoxyhypusine synthase family
protein - Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 336
Score = 38.3 bits (85), Expect = 0.23
Identities = 18/51 (35%), Positives = 31/51 (60%)
Frame = -1
Query: 204 YAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIVA 52
Y ++ ++ GS +GA P+E ++WGK+ + + +DAT+V PLI A
Sbjct: 281 YFCQISDSTTSYGSYSGAVPNEKITWGKLGIDTPKFVIESDATIVAPLIFA 331
>UniRef50_Q5ACN0 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 686
Score = 37.9 bits (84), Expect = 0.30
Identities = 25/76 (32%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = +2
Query: 503 LQTVPSFICSEIISSNNGVTHSSNKQ*LSFGTNKLPILFIPRV-LNTFPLKLKSPT*VGA 679
+Q V + S+ + + N S+ + +F +N LP+LFIP + N L + P
Sbjct: 457 IQLVIKYASSDTVDNANSNNESNMRVYFNFFSNNLPLLFIPEIAYNAGWLDVLIP----- 511
Query: 680 MHFIKSSSIPPAVVTN 727
HFIK ++IPP TN
Sbjct: 512 -HFIKYNNIPPNCRTN 526
>UniRef50_Q20103 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 334
Score = 36.7 bits (81), Expect = 0.69
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Frame = -1
Query: 621 INRIGNLL--VPNDNYCLFEEWVTPLLDEMISEQMKEGTVWSPSRITARLGERINNES 454
INR+ NL +P C+ +EW+TP++ + ++ K G+V S T +L R N+S
Sbjct: 153 INRLANLSGSIPFLEKCIPQEWLTPIVLQASVDEKKRGSVDSAEEATEKLVVRSLNDS 210
>UniRef50_A0LN06 Cluster: Deoxyhypusine synthase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Deoxyhypusine
synthase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 345
Score = 35.9 bits (79), Expect = 1.2
Identities = 15/49 (30%), Positives = 31/49 (63%)
Frame = -1
Query: 204 YAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLI 58
Y ++ ++ GS +GA P+E ++WGK+ ++ + +DA++V PL+
Sbjct: 275 YFCQISDSTTSYGSYSGAVPNEKITWGKLDVDSPRFIIESDASIVLPLV 323
>UniRef50_Q09A08 Cluster: Deoxyhypusine synthase; n=3;
Cystobacterineae|Rep: Deoxyhypusine synthase -
Stigmatella aurantiaca DW4/3-1
Length = 346
Score = 34.7 bits (76), Expect = 2.8
Identities = 15/50 (30%), Positives = 29/50 (58%)
Frame = -1
Query: 204 YAVYVNTASEFDGSDAGARPDEAVSWGKIRPNANPVKLYADATLVFPLIV 55
Y ++ ++ GS +GA P+E ++W K+ + +DAT+V PL++
Sbjct: 274 YFCQISDSTTSYGSYSGATPNEKITWDKLTETTPMFVIESDATIVAPLML 323
>UniRef50_Q029V5 Cluster: Deoxyhypusine synthase; n=1; Solibacter
usitatus Ellin6076|Rep: Deoxyhypusine synthase -
Solibacter usitatus (strain Ellin6076)
Length = 427
Score = 33.5 bits (73), Expect = 6.4
Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Frame = -1
Query: 213 GADYAVYVNTASEFDGSDAGARPDEAVSWGKIRPNA---NPVKLYADATLVFPLIV 55
G + V + TA DGS + P EAV+WGK+ + + +D +LV P +V
Sbjct: 298 GYAFDVQIVTAPVTDGSLSSCPPAEAVTWGKVDKDTYLQTTESMQSDYSLVMPFLV 353
>UniRef50_Q6FZT4 Cluster: Branched chain aa ABC transporter,
periplasmic aa-binding protein; n=3; Proteobacteria|Rep:
Branched chain aa ABC transporter, periplasmic
aa-binding protein - Bartonella quintana (Rochalimaea
quintana)
Length = 377
Score = 33.1 bits (72), Expect = 8.5
Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 2/50 (4%)
Frame = +2
Query: 296 TAMVFNLRRSPNMSMISPGRLNEWKYIMSPKDPSVNA--GLNIGMLFLQA 439
T + +N + PNMS + +NEWK K+P++N+ G M+F++A
Sbjct: 268 TTLPYN-KDMPNMSAAAQEFINEWKATYPDKEPNINSVLGYTSYMMFMKA 316
>UniRef50_A0UWX0 Cluster: Extracellular solute-binding protein,
family 1 precursor; n=1; Clostridium cellulolyticum
H10|Rep: Extracellular solute-binding protein, family 1
precursor - Clostridium cellulolyticum H10
Length = 443
Score = 33.1 bits (72), Expect = 8.5
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 4/70 (5%)
Frame = -1
Query: 654 NLSGKVLRTRGINRI---GNLLVPNDNYCLFE-EWVTPLLDEMISEQMKEGTVWSPSRIT 487
+L V+ GIN I GNL P ++Y + +W + + DE ++ ++G VWS S
Sbjct: 106 DLPDVVMGKNGINEILLKGNLATPFNDYLDKDTQWKSEIGDEALAANTRDGKVWSISDQK 165
Query: 486 ARLGERINNE 457
+G N E
Sbjct: 166 QVIGYFYNKE 175
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 815,379,143
Number of Sequences: 1657284
Number of extensions: 17004954
Number of successful extensions: 37765
Number of sequences better than 10.0: 53
Number of HSP's better than 10.0 without gapping: 36077
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37683
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 69966202150
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -