Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmnc12h06
(829 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC036451-1|AAH36451.1| 484|Homo sapiens cathepsin F protein. 205 2e-52
BC011682-1|AAH11682.1| 484|Homo sapiens cathepsin F protein. 205 2e-52
AJ007331-1|CAB42883.1| 484|Homo sapiens cysteine proteinase pro... 205 2e-52
AF132894-1|AAD41790.1| 484|Homo sapiens cathepsin F protein. 205 2e-52
AF088886-1|AAD26616.2| 484|Homo sapiens cathepsin F precursor p... 205 2e-52
AF071749-1|AAC78839.1| 302|Homo sapiens cathepsin F protein. 205 2e-52
AF071748-1|AAC78838.1| 338|Homo sapiens cathepsin F protein. 205 2e-52
AF136279-1|AAF13146.1| 484|Homo sapiens cathepsin F precursor p... 203 5e-52
CR541680-1|CAG46481.1| 338|Homo sapiens CTSF protein. 202 1e-51
X16832-1|CAA34734.1| 335|Homo sapiens protein ( Human mRNA for ... 188 2e-47
CR456881-1|CAG33162.1| 335|Homo sapiens CTSH protein. 188 2e-47
BC002479-1|AAH02479.1| 335|Homo sapiens cathepsin H protein. 188 2e-47
AF426248-1|AAL23962.1| 323|Homo sapiens truncated cathepsin H p... 188 2e-47
AF426247-1|AAL23961.1| 335|Homo sapiens cathepsin H protein. 188 2e-47
X82153-1|CAA57649.1| 329|Homo sapiens Cathepsin O protein. 183 8e-46
U20280-1|AAA95998.1| 329|Homo sapiens cathepsin X protein. 183 8e-46
U13665-1|AAA65233.1| 329|Homo sapiens cathepsin O protein. 183 8e-46
S79895-1|AAB35521.1| 329|Homo sapiens cathepsin O2 protein. 183 8e-46
CR541719-1|CAG46520.1| 329|Homo sapiens CTSK protein. 183 8e-46
CR541675-1|CAG46476.1| 329|Homo sapiens CTSK protein. 183 8e-46
BC016058-1|AAH16058.1| 329|Homo sapiens cathepsin K protein. 183 8e-46
AL356292-1|CAI13649.1| 329|Homo sapiens cathepsin K protein. 183 8e-46
AL355860-1|CAI12795.1| 329|Homo sapiens cathepsin K protein. 183 8e-46
X77383-1|CAA54562.1| 321|Homo sapiens cathepsin O protein. 181 2e-45
BC049206-1|AAH49206.1| 321|Homo sapiens cathepsin O protein. 181 2e-45
X07549-1|CAA30428.1| 248|Homo sapiens cathepsin H protein. 176 9e-44
CR541676-1|CAG46477.1| 331|Homo sapiens CTSS protein. 165 2e-40
BC002642-1|AAH02642.1| 331|Homo sapiens cathepsin S protein. 165 2e-40
AL356292-9|CAI13657.1| 331|Homo sapiens cathepsin S protein. 165 2e-40
S93414-1|AAB22005.1| 331|Homo sapiens cathepsin S protein. 164 3e-40
M86553-1|AAA35655.1| 331|Homo sapiens cathepsin protein. 164 3e-40
M90696-1|AAC37592.1| 331|Homo sapiens cathepsin S protein. 164 4e-40
X12451-1|CAA30981.1| 333|Homo sapiens pro-(cathepsin L) protein. 161 2e-39
M20496-1|AAA66974.1| 333|Homo sapiens CTSL protein. 161 2e-39
CR457053-1|CAG33334.1| 333|Homo sapiens CTSL protein. 161 2e-39
BC012612-1|AAH12612.1| 333|Homo sapiens cathepsin L1 protein. 161 2e-39
AL160279-3|CAI16308.1| 333|Homo sapiens cathepsin L1 protein. 161 2e-39
BC142983-1|AAI42984.1| 333|Homo sapiens cathepsin L1 protein. 161 4e-39
AL137742-1|CAB70900.1| 308|Homo sapiens hypothetical protein pr... 153 1e-36
Y14734-1|CAA75029.1| 334|Homo sapiens cathepsin L2 protein. 151 3e-36
BC110512-1|AAI10513.1| 334|Homo sapiens cathepsin L2 protein. 151 3e-36
BC023504-1|AAH23504.1| 334|Homo sapiens CTSL2 protein protein. 151 3e-36
AY358641-1|AAQ89004.1| 334|Homo sapiens cathepsin L2 protein. 151 3e-36
AL445670-2|CAI15053.1| 334|Homo sapiens cathepsin L2 protein. 151 3e-36
AF070448-1|AAC23598.1| 334|Homo sapiens cathepsin U protein. 151 3e-36
AB019534-1|BAA34365.1| 334|Homo sapiens cathepsin L2 protein. 151 3e-36
AB001928-1|BAA25909.1| 334|Homo sapiens cathepsin V protein. 151 3e-36
Y18461-1|CAA77179.1| 166|Homo sapiens cathepsin H protein. 134 3e-31
BC048255-1|AAH48255.1| 376|Homo sapiens cathepsin W protein. 133 6e-31
Y18462-1|CAA77180.1| 175|Homo sapiens cathepsin L protein. 132 2e-30
AF055903-1|AAC32181.1| 376|Homo sapiens cathepsin W protein. 131 3e-30
AF015954-1|AAB82457.1| 376|Homo sapiens lymphopain protein. 131 3e-30
AF013611-1|AAB82449.1| 376|Homo sapiens lymphopain protein. 131 3e-30
X87212-1|CAA60671.1| 463|Homo sapiens cathepsin C protein. 120 6e-27
U79415-1|AAC51341.1| 463|Homo sapiens prepro dipeptidyl peptida... 120 6e-27
U07374-1|AAB60643.2| 267|Homo sapiens cathepsin S protein. 120 6e-27
AK223038-1|BAD96758.1| 463|Homo sapiens cathepsin C isoform a p... 120 6e-27
AF234263-1|AAL48191.1| 463|Homo sapiens cathepsin C protein. 120 6e-27
AF525032-1|AAQ08887.1| 463|Homo sapiens cathepsin C protein. 119 1e-26
AF234264-1|AAL48192.1| 463|Homo sapiens cathepsin C protein. 116 8e-26
AF254757-1|AAL48195.1| 463|Homo sapiens cathepsin C protein. 116 1e-25
AL355860-2|CAI12796.1| 258|Homo sapiens cathepsin K protein. 105 3e-22
AL160279-2|CAI16307.1| 225|Homo sapiens cathepsin L1 protein. 101 3e-21
AF217997-1|AAG17239.1| 151|Homo sapiens unknown protein. 87 1e-16
BT019915-1|AAV38718.1| 303|Homo sapiens cathepsin Z protein. 79 1e-14
BC042168-1|AAH42168.1| 303|Homo sapiens cathepsin Z protein. 79 1e-14
AL109840-6|CAC09370.1| 303|Homo sapiens cathepsin Z protein. 79 1e-14
AF136276-1|AAF13148.1| 303|Homo sapiens cathepsin Z precursor p... 79 1e-14
AF136273-1|AAF13145.1| 303|Homo sapiens cathepsin Z precursor p... 79 1e-14
AF032906-1|AAC39839.1| 303|Homo sapiens cathepsin Z precursor p... 79 1e-14
AF009923-1|AAC63141.1| 293|Homo sapiens preprocathepsin P protein. 79 1e-14
AF073890-1|AAC61477.1| 303|Homo sapiens cathepsin X precursor p... 79 3e-14
M14221-1|AAA52129.1| 339|Homo sapiens CTSB protein. 74 6e-13
M13230-1|AAA52125.1| 209|Homo sapiens CTSB protein. 74 6e-13
L16510-1|AAC37547.1| 339|Homo sapiens cathepsin B protein. 74 6e-13
BC095408-1|AAH95408.1| 339|Homo sapiens cathepsin B protein. 74 6e-13
BC010240-1|AAH10240.1| 339|Homo sapiens cathepsin B protein. 74 6e-13
BC025419-1|AAH25419.1| 297|Homo sapiens CTSZ protein protein. 70 1e-11
BC070278-1|AAH70278.1| 476|Homo sapiens tubulointerstitial neph... 61 4e-09
BC064633-1|AAH64633.1| 467|Homo sapiens tubulointerstitial neph... 61 4e-09
AY358421-1|AAQ88787.1| 467|Homo sapiens LCN7 protein. 61 4e-09
AL589946-2|CAH70302.1| 476|Homo sapiens tubulointerstitial neph... 61 4e-09
AL359380-5|CAI16272.1| 476|Homo sapiens tubulointerstitial neph... 61 4e-09
AK075398-1|BAC11596.1| 467|Homo sapiens protein ( Homo sapiens ... 61 4e-09
AF236155-1|AAG40154.1| 467|Homo sapiens tubulointerstitial neph... 61 4e-09
AF236150-1|AAG38876.1| 467|Homo sapiens tubulointerstitial neph... 61 4e-09
AF205436-1|AAG33699.1| 467|Homo sapiens oxidized-LDL responsive... 61 4e-09
AB050719-1|BAB18727.1| 467|Homo sapiens glucocorticoid-inducibl... 61 4e-09
AB050716-1|BAB18636.1| 467|Homo sapiens glucocorticoid-inducibl... 61 4e-09
AB022277-1|BAA84949.1| 476|Homo sapiens tubulointerstitial neph... 61 4e-09
AF195116-1|AAF08931.1| 476|Homo sapiens tubulointerstitial neph... 60 1e-08
X05256-1|CAA28877.1| 42|Homo sapiens protein ( Human mRNA frag... 54 6e-07
BC009048-1|AAH09048.1| 218|Homo sapiens TINAGL1 protein protein. 51 4e-06
AK027839-1|BAB55403.1| 218|Homo sapiens protein ( Homo sapiens ... 50 1e-05
Y18460-1|CAA77178.1| 195|Homo sapiens cathepsin B protein. 45 4e-04
AL589946-1|CAH70301.1| 155|Homo sapiens tubulointerstitial neph... 45 4e-04
AF195117-1|AAF08932.1| 333|Homo sapiens tubulointerstitial neph... 45 4e-04
AK074124-1|BAB84950.1| 284|Homo sapiens FLJ00196 protein protein. 33 0.95
BC089428-1|AAH89428.1| 1192|Homo sapiens PLEKHG1 protein protein. 31 6.7
AL450339-2|CAI12939.1| 1385|Homo sapiens pleckstrin homology dom... 31 6.7
AL035086-3|CAI42790.1| 1385|Homo sapiens pleckstrin homology dom... 31 6.7
AB033035-1|BAA86523.1| 1113|Homo sapiens KIAA1209 protein protein. 31 6.7
>BC036451-1|AAH36451.1| 484|Homo sapiens cathepsin F protein.
Length = 484
Score = 205 bits (500), Expect = 2e-52
Identities = 102/260 (39%), Positives = 155/260 (59%), Gaps = 4/260 (1%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTS 626
+A+Y + KFSDL+++E Y L + N K+ P E+DWR VT
Sbjct: 228 TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTK 285
Query: 625 VKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAI 446
VK+QGMCG+CWAF+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI
Sbjct: 286 VKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAI 345
Query: 445 IKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAI 266
+GG++ E DY Y+ +C ++ K V + D + E+KL L GPI +AI
Sbjct: 346 KNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVE-LSQNEQKLAAWLAKRGPISVAI 404
Query: 265 DAADIVNYKQGIIK----YCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+A + Y+ GI + C ++HAVLLVGYG +++P+W KN+WGTDWGE G++
Sbjct: 405 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYY 464
Query: 97 VQQNINACGMRNELASTAVI 38
+ + ACG+ N +AS+AV+
Sbjct: 465 LHRGSGACGV-NTMASSAVV 483
>BC011682-1|AAH11682.1| 484|Homo sapiens cathepsin F protein.
Length = 484
Score = 205 bits (500), Expect = 2e-52
Identities = 102/260 (39%), Positives = 155/260 (59%), Gaps = 4/260 (1%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTS 626
+A+Y + KFSDL+++E Y L + N K+ P E+DWR VT
Sbjct: 228 TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTK 285
Query: 625 VKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAI 446
VK+QGMCG+CWAF+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI
Sbjct: 286 VKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAI 345
Query: 445 IKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAI 266
+GG++ E DY Y+ +C ++ K V + D + E+KL L GPI +AI
Sbjct: 346 KNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVE-LSQNEQKLAAWLAKRGPISVAI 404
Query: 265 DAADIVNYKQGIIK----YCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+A + Y+ GI + C ++HAVLLVGYG +++P+W KN+WGTDWGE G++
Sbjct: 405 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYY 464
Query: 97 VQQNINACGMRNELASTAVI 38
+ + ACG+ N +AS+AV+
Sbjct: 465 LHRGSGACGV-NTMASSAVV 483
>AJ007331-1|CAB42883.1| 484|Homo sapiens cysteine proteinase
protein.
Length = 484
Score = 205 bits (500), Expect = 2e-52
Identities = 102/260 (39%), Positives = 155/260 (59%), Gaps = 4/260 (1%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTS 626
+A+Y + KFSDL+++E Y L + N K+ P E+DWR VT
Sbjct: 228 TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTK 285
Query: 625 VKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAI 446
VK+QGMCG+CWAF+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI
Sbjct: 286 VKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAI 345
Query: 445 IKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAI 266
+GG++ E DY Y+ +C ++ K V + D + E+KL L GPI +AI
Sbjct: 346 KNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVE-LSQNEQKLAAWLAKRGPISVAI 404
Query: 265 DAADIVNYKQGIIK----YCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+A + Y+ GI + C ++HAVLLVGYG +++P+W KN+WGTDWGE G++
Sbjct: 405 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYY 464
Query: 97 VQQNINACGMRNELASTAVI 38
+ + ACG+ N +AS+AV+
Sbjct: 465 LHRGSGACGV-NTMASSAVV 483
>AF132894-1|AAD41790.1| 484|Homo sapiens cathepsin F protein.
Length = 484
Score = 205 bits (500), Expect = 2e-52
Identities = 102/260 (39%), Positives = 155/260 (59%), Gaps = 4/260 (1%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTS 626
+A+Y + KFSDL+++E Y L + N K+ P E+DWR VT
Sbjct: 228 TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTK 285
Query: 625 VKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAI 446
VK+QGMCG+CWAF+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI
Sbjct: 286 VKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAI 345
Query: 445 IKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAI 266
+GG++ E DY Y+ +C ++ K V + D + E+KL L GPI +AI
Sbjct: 346 KNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVE-LSQNEQKLAAWLAKRGPISVAI 404
Query: 265 DAADIVNYKQGIIK----YCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+A + Y+ GI + C ++HAVLLVGYG +++P+W KN+WGTDWGE G++
Sbjct: 405 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYY 464
Query: 97 VQQNINACGMRNELASTAVI 38
+ + ACG+ N +AS+AV+
Sbjct: 465 LHRGSGACGV-NTMASSAVV 483
>AF088886-1|AAD26616.2| 484|Homo sapiens cathepsin F precursor
protein.
Length = 484
Score = 205 bits (500), Expect = 2e-52
Identities = 102/260 (39%), Positives = 155/260 (59%), Gaps = 4/260 (1%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTS 626
+A+Y + KFSDL+++E Y L + N K+ P E+DWR VT
Sbjct: 228 TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTK 285
Query: 625 VKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAI 446
VK+QGMCG+CWAF+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI
Sbjct: 286 VKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAI 345
Query: 445 IKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAI 266
+GG++ E DY Y+ +C ++ K V + D + E+KL L GPI +AI
Sbjct: 346 KNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVE-LSQNEQKLAAWLAKRGPISVAI 404
Query: 265 DAADIVNYKQGIIK----YCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+A + Y+ GI + C ++HAVLLVGYG +++P+W KN+WGTDWGE G++
Sbjct: 405 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYY 464
Query: 97 VQQNINACGMRNELASTAVI 38
+ + ACG+ N +AS+AV+
Sbjct: 465 LHRGSGACGV-NTMASSAVV 483
>AF071749-1|AAC78839.1| 302|Homo sapiens cathepsin F protein.
Length = 302
Score = 205 bits (500), Expect = 2e-52
Identities = 102/260 (39%), Positives = 155/260 (59%), Gaps = 4/260 (1%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTS 626
+A+Y + KFSDL+++E Y L + N K+ P E+DWR VT
Sbjct: 46 TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTK 103
Query: 625 VKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAI 446
VK+QGMCG+CWAF+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI
Sbjct: 104 VKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAI 163
Query: 445 IKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAI 266
+GG++ E DY Y+ +C ++ K V + D + E+KL L GPI +AI
Sbjct: 164 KNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVE-LSQNEQKLAAWLAKRGPISVAI 222
Query: 265 DAADIVNYKQGIIK----YCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+A + Y+ GI + C ++HAVLLVGYG +++P+W KN+WGTDWGE G++
Sbjct: 223 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYY 282
Query: 97 VQQNINACGMRNELASTAVI 38
+ + ACG+ N +AS+AV+
Sbjct: 283 LHRGSGACGV-NTMASSAVV 301
>AF071748-1|AAC78838.1| 338|Homo sapiens cathepsin F protein.
Length = 338
Score = 205 bits (500), Expect = 2e-52
Identities = 102/260 (39%), Positives = 155/260 (59%), Gaps = 4/260 (1%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTS 626
+A+Y + KFSDL+++E Y L + N K+ P E+DWR VT
Sbjct: 82 TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTK 139
Query: 625 VKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAI 446
VK+QGMCG+CWAF+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI
Sbjct: 140 VKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAI 199
Query: 445 IKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAI 266
+GG++ E DY Y+ +C ++ K V + D + E+KL L GPI +AI
Sbjct: 200 KNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVE-LSQNEQKLAAWLAKRGPISVAI 258
Query: 265 DAADIVNYKQGIIK----YCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+A + Y+ GI + C ++HAVLLVGYG +++P+W KN+WGTDWGE G++
Sbjct: 259 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYY 318
Query: 97 VQQNINACGMRNELASTAVI 38
+ + ACG+ N +AS+AV+
Sbjct: 319 LHRGSGACGV-NTMASSAVV 337
>AF136279-1|AAF13146.1| 484|Homo sapiens cathepsin F precursor
protein.
Length = 484
Score = 203 bits (496), Expect = 5e-52
Identities = 101/260 (38%), Positives = 155/260 (59%), Gaps = 4/260 (1%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTS 626
+A+Y + KFSDL+++E Y L + N K+ P E+DWR VT
Sbjct: 228 TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTK 285
Query: 625 VKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAI 446
VK+QGMCG+CWAF+ G+++ Q+ + L++LSEQ+++DCD +D C GGL A+ AI
Sbjct: 286 VKDQGMCGSCWAFSVTGNVKGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAI 345
Query: 445 IKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAI 266
+GG++ E DY Y+ +C ++ K V + D + E+KL L GPI +AI
Sbjct: 346 KNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVE-LSQNEQKLAAWLAKRGPISVAI 404
Query: 265 DAADIVNYKQGIIK----YCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+A + Y+ GI + C ++HAVLLVGYG +++P+W KN+WGTDWGE G++
Sbjct: 405 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYY 464
Query: 97 VQQNINACGMRNELASTAVI 38
+ + ACG+ N +AS+AV+
Sbjct: 465 LHRGSGACGV-NTMASSAVV 483
>CR541680-1|CAG46481.1| 338|Homo sapiens CTSF protein.
Length = 338
Score = 202 bits (493), Expect = 1e-51
Identities = 101/260 (38%), Positives = 154/260 (59%), Gaps = 4/260 (1%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTS 626
+A+Y + KFSDL+++E Y L + N K+ P E+DWR VT
Sbjct: 82 TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTK 139
Query: 625 VKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAI 446
VK+QGMCG+CWAF+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI
Sbjct: 140 VKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAI 199
Query: 445 IKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAI 266
+GG++ DY Y+ +C ++ K V + D + E+KL L GPI +AI
Sbjct: 200 KNLGGLETVDDYSYQGHMQSCNFSAEKAKVYINDSVE-LSQNEQKLAAWLAKRGPISVAI 258
Query: 265 DAADIVNYKQGIIK----YCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+A + Y+ GI + C ++HAVLLVGYG +++P+W KN+WGTDWGE G++
Sbjct: 259 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYY 318
Query: 97 VQQNINACGMRNELASTAVI 38
+ + ACG+ N +AS+AV+
Sbjct: 319 LHRGSGACGV-NTMASSAVV 337
>X16832-1|CAA34734.1| 335|Homo sapiens protein ( Human mRNA for
cathepsin H (EC 3.4.22.16). ).
Length = 335
Score = 188 bits (459), Expect = 2e-47
Identities = 103/262 (39%), Positives = 147/262 (56%), Gaps = 10/262 (3%)
Frame = -1
Query: 823 NKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPL--EFDW 650
+ N N + K +N+FSD+S E KY L ++ QN C + G GP DW
Sbjct: 68 HNNGNHTFKMALNQFSDMSFAEIKHKY----LWSEPQN-CSATKSNYLRGTGPYPPSVDW 122
Query: 649 RRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC--DFVDAGCN 479
R+ N V+ VKNQG CG+CW F+T G+LES AI ++++L+EQQ++DC DF + GC
Sbjct: 123 RKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNYGCQ 182
Query: 478 GGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDL 299
GGL AFE I+ G+ E YPY+ + C+ K + VKD I EE + +
Sbjct: 183 GGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEA 242
Query: 298 LRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG--LNHAVLLVGYGVENNIPYWTFKNT 134
+ L P+ A + D + Y+ GI C + +NHAVL VGYG +N IPYW KN+
Sbjct: 243 VALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNS 302
Query: 133 WGTDWGEDGFFRVQQNINACGM 68
WG WG +G+F +++ N CG+
Sbjct: 303 WGPQWGMNGYFLIERGKNMCGL 324
>CR456881-1|CAG33162.1| 335|Homo sapiens CTSH protein.
Length = 335
Score = 188 bits (459), Expect = 2e-47
Identities = 103/262 (39%), Positives = 147/262 (56%), Gaps = 10/262 (3%)
Frame = -1
Query: 823 NKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPL--EFDW 650
+ N N + K +N+FSD+S E KY L ++ QN C + G GP DW
Sbjct: 68 HNNGNHTFKMALNQFSDMSFAEIKHKY----LWSEPQN-CSATKSNYLRGTGPYPPSVDW 122
Query: 649 RRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC--DFVDAGCN 479
R+ N V+ VKNQG CG+CW F+T G+LES AI ++++L+EQQ++DC DF + GC
Sbjct: 123 RKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQ 182
Query: 478 GGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDL 299
GGL AFE I+ G+ E YPY+ + C+ K + VKD I EE + +
Sbjct: 183 GGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEA 242
Query: 298 LRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG--LNHAVLLVGYGVENNIPYWTFKNT 134
+ L P+ A + D + Y+ GI C + +NHAVL VGYG +N IPYW KN+
Sbjct: 243 VALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNS 302
Query: 133 WGTDWGEDGFFRVQQNINACGM 68
WG WG +G+F +++ N CG+
Sbjct: 303 WGPQWGMNGYFLIERGKNMCGL 324
>BC002479-1|AAH02479.1| 335|Homo sapiens cathepsin H protein.
Length = 335
Score = 188 bits (459), Expect = 2e-47
Identities = 103/262 (39%), Positives = 147/262 (56%), Gaps = 10/262 (3%)
Frame = -1
Query: 823 NKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPL--EFDW 650
+ N N + K +N+FSD+S E KY L ++ QN C + G GP DW
Sbjct: 68 HNNGNHTFKMALNQFSDMSFAEIKHKY----LWSEPQN-CSATKSNYLRGTGPYPPSVDW 122
Query: 649 RRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC--DFVDAGCN 479
R+ N V+ VKNQG CG+CW F+T G+LES AI ++++L+EQQ++DC DF + GC
Sbjct: 123 RKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQ 182
Query: 478 GGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDL 299
GGL AFE I+ G+ E YPY+ + C+ K + VKD I EE + +
Sbjct: 183 GGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEA 242
Query: 298 LRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG--LNHAVLLVGYGVENNIPYWTFKNT 134
+ L P+ A + D + Y+ GI C + +NHAVL VGYG +N IPYW KN+
Sbjct: 243 VALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNS 302
Query: 133 WGTDWGEDGFFRVQQNINACGM 68
WG WG +G+F +++ N CG+
Sbjct: 303 WGPQWGMNGYFLIERGKNMCGL 324
>AF426248-1|AAL23962.1| 323|Homo sapiens truncated cathepsin H
protein.
Length = 323
Score = 188 bits (459), Expect = 2e-47
Identities = 103/262 (39%), Positives = 147/262 (56%), Gaps = 10/262 (3%)
Frame = -1
Query: 823 NKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPL--EFDW 650
+ N N + K +N+FSD+S E KY L ++ QN C + G GP DW
Sbjct: 56 HNNGNHTFKMALNQFSDMSFAEIKHKY----LWSEPQN-CSATKSNYLRGTGPYPPSVDW 110
Query: 649 RRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC--DFVDAGCN 479
R+ N V+ VKNQG CG+CW F+T G+LES AI ++++L+EQQ++DC DF + GC
Sbjct: 111 RKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNYGCQ 170
Query: 478 GGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDL 299
GGL AFE I+ G+ E YPY+ + C+ K + VKD I EE + +
Sbjct: 171 GGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEA 230
Query: 298 LRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG--LNHAVLLVGYGVENNIPYWTFKNT 134
+ L P+ A + D + Y+ GI C + +NHAVL VGYG +N IPYW KN+
Sbjct: 231 VALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNS 290
Query: 133 WGTDWGEDGFFRVQQNINACGM 68
WG WG +G+F +++ N CG+
Sbjct: 291 WGPQWGMNGYFLIERGKNMCGL 312
>AF426247-1|AAL23961.1| 335|Homo sapiens cathepsin H protein.
Length = 335
Score = 188 bits (459), Expect = 2e-47
Identities = 103/262 (39%), Positives = 147/262 (56%), Gaps = 10/262 (3%)
Frame = -1
Query: 823 NKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPL--EFDW 650
+ N N + K +N+FSD+S E KY L ++ QN C + G GP DW
Sbjct: 68 HNNGNHTFKMALNQFSDMSFAEIKHKY----LWSEPQN-CSATKSNYLRGTGPYPPSVDW 122
Query: 649 RRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC--DFVDAGCN 479
R+ N V+ VKNQG CG+CW F+T G+LES AI ++++L+EQQ++DC DF + GC
Sbjct: 123 RKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNYGCQ 182
Query: 478 GGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDL 299
GGL AFE I+ G+ E YPY+ + C+ K + VKD I EE + +
Sbjct: 183 GGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEA 242
Query: 298 LRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG--LNHAVLLVGYGVENNIPYWTFKNT 134
+ L P+ A + D + Y+ GI C + +NHAVL VGYG +N IPYW KN+
Sbjct: 243 VALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNGIPYWIVKNS 302
Query: 133 WGTDWGEDGFFRVQQNINACGM 68
WG WG +G+F +++ N CG+
Sbjct: 303 WGPQWGMNGYFLIERGKNMCGL 324
>X82153-1|CAA57649.1| 329|Homo sapiens Cathepsin O protein.
Length = 329
Score = 183 bits (445), Expect = 8e-46
Identities = 95/253 (37%), Positives = 140/253 (55%), Gaps = 6/253 (2%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E + K TGL +P + + + G+ P D+R+ VT VKNQG
Sbjct: 75 MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGG 431
CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ + K G
Sbjct: 135 QCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRG 194
Query: 430 VQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA- 257
+ E YPY +C N + + YR I EK LK + VGP+ +AIDA+
Sbjct: 195 IDSEDAYPYVGQEESCMYNPTGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASL 253
Query: 256 -DIVNYKQGII--KYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN 86
Y +G+ + C LNHAVL VGYG++ +W KN+WG +WG G+ + +N
Sbjct: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313
Query: 85 -INACGMRNELAS 50
NACG+ N LAS
Sbjct: 314 KNNACGIAN-LAS 325
>U20280-1|AAA95998.1| 329|Homo sapiens cathepsin X protein.
Length = 329
Score = 183 bits (445), Expect = 8e-46
Identities = 95/253 (37%), Positives = 140/253 (55%), Gaps = 6/253 (2%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E + K TGL +P + + + G+ P D+R+ VT VKNQG
Sbjct: 75 MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGG 431
CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ + K G
Sbjct: 135 QCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRG 194
Query: 430 VQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA- 257
+ E YPY +C N + + YR I EK LK + VGP+ +AIDA+
Sbjct: 195 IDSEDAYPYVGQEESCMYNPTGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASL 253
Query: 256 -DIVNYKQGII--KYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN 86
Y +G+ + C LNHAVL VGYG++ +W KN+WG +WG G+ + +N
Sbjct: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313
Query: 85 -INACGMRNELAS 50
NACG+ N LAS
Sbjct: 314 KNNACGIAN-LAS 325
>U13665-1|AAA65233.1| 329|Homo sapiens cathepsin O protein.
Length = 329
Score = 183 bits (445), Expect = 8e-46
Identities = 95/253 (37%), Positives = 140/253 (55%), Gaps = 6/253 (2%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E + K TGL +P + + + G+ P D+R+ VT VKNQG
Sbjct: 75 MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGG 431
CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ + K G
Sbjct: 135 QCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRG 194
Query: 430 VQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA- 257
+ E YPY +C N + + YR I EK LK + VGP+ +AIDA+
Sbjct: 195 IDSEDAYPYVGQEESCMYNPTGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASL 253
Query: 256 -DIVNYKQGII--KYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN 86
Y +G+ + C LNHAVL VGYG++ +W KN+WG +WG G+ + +N
Sbjct: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313
Query: 85 -INACGMRNELAS 50
NACG+ N LAS
Sbjct: 314 KNNACGIAN-LAS 325
>S79895-1|AAB35521.1| 329|Homo sapiens cathepsin O2 protein.
Length = 329
Score = 183 bits (445), Expect = 8e-46
Identities = 95/253 (37%), Positives = 140/253 (55%), Gaps = 6/253 (2%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E + K TGL +P + + + G+ P D+R+ VT VKNQG
Sbjct: 75 MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGG 431
CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ + K G
Sbjct: 135 QCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRG 194
Query: 430 VQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA- 257
+ E YPY +C N + + YR I EK LK + VGP+ +AIDA+
Sbjct: 195 IDSEDAYPYVGQEESCMYNPTGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASL 253
Query: 256 -DIVNYKQGII--KYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN 86
Y +G+ + C LNHAVL VGYG++ +W KN+WG +WG G+ + +N
Sbjct: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313
Query: 85 -INACGMRNELAS 50
NACG+ N LAS
Sbjct: 314 KNNACGIAN-LAS 325
>CR541719-1|CAG46520.1| 329|Homo sapiens CTSK protein.
Length = 329
Score = 183 bits (445), Expect = 8e-46
Identities = 95/253 (37%), Positives = 140/253 (55%), Gaps = 6/253 (2%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E + K TGL +P + + + G+ P D+R+ VT VKNQG
Sbjct: 75 MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGG 431
CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ + K G
Sbjct: 135 QCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRG 194
Query: 430 VQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA- 257
+ E YPY +C N + + YR I EK LK + VGP+ +AIDA+
Sbjct: 195 IDSEDAYPYVGQEESCMYNPTGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASL 253
Query: 256 -DIVNYKQGII--KYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN 86
Y +G+ + C LNHAVL VGYG++ +W KN+WG +WG G+ + +N
Sbjct: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313
Query: 85 -INACGMRNELAS 50
NACG+ N LAS
Sbjct: 314 KNNACGIAN-LAS 325
>CR541675-1|CAG46476.1| 329|Homo sapiens CTSK protein.
Length = 329
Score = 183 bits (445), Expect = 8e-46
Identities = 95/253 (37%), Positives = 140/253 (55%), Gaps = 6/253 (2%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E + K TGL +P + + + G+ P D+R+ VT VKNQG
Sbjct: 75 MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGG 431
CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ + K G
Sbjct: 135 QCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRG 194
Query: 430 VQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA- 257
+ E YPY +C N + + YR I EK LK + VGP+ +AIDA+
Sbjct: 195 IDSEDAYPYVGQEESCMYNPTGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASL 253
Query: 256 -DIVNYKQGII--KYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN 86
Y +G+ + C LNHAVL VGYG++ +W KN+WG +WG G+ + +N
Sbjct: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313
Query: 85 -INACGMRNELAS 50
NACG+ N LAS
Sbjct: 314 KNNACGIAN-LAS 325
>BC016058-1|AAH16058.1| 329|Homo sapiens cathepsin K protein.
Length = 329
Score = 183 bits (445), Expect = 8e-46
Identities = 95/253 (37%), Positives = 140/253 (55%), Gaps = 6/253 (2%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E + K TGL +P + + + G+ P D+R+ VT VKNQG
Sbjct: 75 MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGG 431
CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ + K G
Sbjct: 135 QCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRG 194
Query: 430 VQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA- 257
+ E YPY +C N + + YR I EK LK + VGP+ +AIDA+
Sbjct: 195 IDSEDAYPYVGQEESCMYNPTGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASL 253
Query: 256 -DIVNYKQGII--KYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN 86
Y +G+ + C LNHAVL VGYG++ +W KN+WG +WG G+ + +N
Sbjct: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313
Query: 85 -INACGMRNELAS 50
NACG+ N LAS
Sbjct: 314 KNNACGIAN-LAS 325
>AL356292-1|CAI13649.1| 329|Homo sapiens cathepsin K protein.
Length = 329
Score = 183 bits (445), Expect = 8e-46
Identities = 95/253 (37%), Positives = 140/253 (55%), Gaps = 6/253 (2%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E + K TGL +P + + + G+ P D+R+ VT VKNQG
Sbjct: 75 MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGG 431
CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ + K G
Sbjct: 135 QCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRG 194
Query: 430 VQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA- 257
+ E YPY +C N + + YR I EK LK + VGP+ +AIDA+
Sbjct: 195 IDSEDAYPYVGQEESCMYNPTGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASL 253
Query: 256 -DIVNYKQGII--KYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN 86
Y +G+ + C LNHAVL VGYG++ +W KN+WG +WG G+ + +N
Sbjct: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313
Query: 85 -INACGMRNELAS 50
NACG+ N LAS
Sbjct: 314 KNNACGIAN-LAS 325
>AL355860-1|CAI12795.1| 329|Homo sapiens cathepsin K protein.
Length = 329
Score = 183 bits (445), Expect = 8e-46
Identities = 95/253 (37%), Positives = 140/253 (55%), Gaps = 6/253 (2%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E + K TGL +P + + + G+ P D+R+ VT VKNQG
Sbjct: 75 MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGG 431
CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ + K G
Sbjct: 135 QCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRG 194
Query: 430 VQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA- 257
+ E YPY +C N + + YR I EK LK + VGP+ +AIDA+
Sbjct: 195 IDSEDAYPYVGQEESCMYNPTGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASL 253
Query: 256 -DIVNYKQGII--KYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN 86
Y +G+ + C LNHAVL VGYG++ +W KN+WG +WG G+ + +N
Sbjct: 254 TSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARN 313
Query: 85 -INACGMRNELAS 50
NACG+ N LAS
Sbjct: 314 KNNACGIAN-LAS 325
>X77383-1|CAA54562.1| 321|Homo sapiens cathepsin O protein.
Length = 321
Score = 181 bits (441), Expect = 2e-45
Identities = 100/265 (37%), Positives = 148/265 (55%), Gaps = 6/265 (2%)
Frame = -1
Query: 817 NQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLN 638
++N +A Y IN+FS L +E A Y S P++ + + + P PL FDWR
Sbjct: 60 SENSTAFYGINQFSYLFPEEFKAIYLR-SKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQ 118
Query: 637 KVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTA 458
VT V+NQ MCG CWAF+ +G++ES +AIK L +LS QQ+IDC + + GCNGG A
Sbjct: 119 VVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCSYNNYGCNGGSTLNA 178
Query: 457 FEAIIKMGGVQL--ESDYPYEADNNNCRMNSNK---FLVQVKDCYRYIIVYEEKLKDLLR 293
+ KM V+L +S+YP++A N C S F ++ Y + +E K LL
Sbjct: 179 LNWLNKM-QVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKGYSAYDFSDQEDEMAKALLT 237
Query: 292 LVGPIPMAIDAADIVNYKQGIIK-YCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWG 116
GP+ + +DA +Y GII+ +C NHAVL+ G+ + PYW +N+WG+ WG
Sbjct: 238 F-GPLVVIVDAVSWQDYLGGIIQHHCSSGEANHAVLITGFDKTGSTPYWIVRNSWGSSWG 296
Query: 115 EDGFFRVQQNINACGMRNELASTAV 41
DG+ V+ N CG+ + ++S V
Sbjct: 297 VDGYAHVKMGSNVCGIADSVSSIFV 321
>BC049206-1|AAH49206.1| 321|Homo sapiens cathepsin O protein.
Length = 321
Score = 181 bits (441), Expect = 2e-45
Identities = 100/265 (37%), Positives = 148/265 (55%), Gaps = 6/265 (2%)
Frame = -1
Query: 817 NQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLN 638
++N +A Y IN+FS L +E A Y S P++ + + + P PL FDWR
Sbjct: 60 SENSTAFYGINQFSYLFPEEFKAIYLR-SKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQ 118
Query: 637 KVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTA 458
VT V+NQ MCG CWAF+ +G++ES +AIK L +LS QQ+IDC + + GCNGG A
Sbjct: 119 VVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCSYNNYGCNGGSTLNA 178
Query: 457 FEAIIKMGGVQL--ESDYPYEADNNNCRMNSNK---FLVQVKDCYRYIIVYEEKLKDLLR 293
+ KM V+L +S+YP++A N C S F ++ Y + +E K LL
Sbjct: 179 LNWLNKM-QVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKGYSAYDFSDQEDEMAKALLT 237
Query: 292 LVGPIPMAIDAADIVNYKQGIIK-YCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWG 116
GP+ + +DA +Y GII+ +C NHAVL+ G+ + PYW +N+WG+ WG
Sbjct: 238 F-GPLVVIVDAVSWQDYLGGIIQHHCSSGEANHAVLITGFDKTGSTPYWIVRNSWGSSWG 296
Query: 115 EDGFFRVQQNINACGMRNELASTAV 41
DG+ V+ N CG+ + ++S V
Sbjct: 297 VDGYAHVKMGSNVCGIADSVSSIFV 321
>X07549-1|CAA30428.1| 248|Homo sapiens cathepsin H protein.
Length = 248
Score = 176 bits (428), Expect = 9e-44
Identities = 87/211 (41%), Positives = 123/211 (58%), Gaps = 8/211 (3%)
Frame = -1
Query: 676 GKGPLEFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC- 503
G P DWR+ N V+ VKNQG CG+CW F+T G+LES AI ++++L+EQQ++DC
Sbjct: 27 GPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCA 86
Query: 502 -DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYII 326
DF + GC GGL AFE I+ G+ E YPY+ + C+ K + VKD I
Sbjct: 87 QDFNNYGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITI 146
Query: 325 VYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG--LNHAVLLVGYGVENN 161
EE + + + L P+ A + D + Y+ GI C + +NHAVL VGYG +N
Sbjct: 147 YDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNG 206
Query: 160 IPYWTFKNTWGTDWGEDGFFRVQQNINACGM 68
IPYW KN+WG WG +G+F +++ N CG+
Sbjct: 207 IPYWIVKNSWGPQWGMNGYFLIERGKNMCGL 237
>CR541676-1|CAG46477.1| 331|Homo sapiens CTSS protein.
Length = 331
Score = 165 bits (401), Expect = 2e-40
Identities = 88/251 (35%), Positives = 141/251 (56%), Gaps = 10/251 (3%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E ++ + L +P+Q Q + P P DWR VT VK QG
Sbjct: 77 MNHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNWILPDSVDWREKGCVTEVKYQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIK 440
CGACWAF+ +G+LE+Q +K +L++LS Q ++DC + + GCNGG + TAF+ II
Sbjct: 135 SCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIID 194
Query: 439 MGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMA 269
G+ ++ YPY+A + C+ +S + C +Y + Y E+ LK+ + GP+ +
Sbjct: 195 NKGIDSDASYPYKAMDQKCQYDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVG 251
Query: 268 IDA--ADIVNYKQGI-IKYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+DA Y+ G+ + +NH VL+VGYG N YW KN+WG ++GE+G+ R
Sbjct: 252 VDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311
Query: 97 VQQNI-NACGM 68
+ +N N CG+
Sbjct: 312 MARNKGNHCGI 322
>BC002642-1|AAH02642.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 165 bits (401), Expect = 2e-40
Identities = 88/251 (35%), Positives = 141/251 (56%), Gaps = 10/251 (3%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E ++ + L +P+Q Q + P P DWR VT VK QG
Sbjct: 77 MNHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNWILPDSVDWREKGCVTEVKYQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIK 440
CGACWAF+ +G+LE+Q +K +L++LS Q ++DC + + GCNGG + TAF+ II
Sbjct: 135 SCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIID 194
Query: 439 MGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMA 269
G+ ++ YPY+A + C+ +S + C +Y + Y E+ LK+ + GP+ +
Sbjct: 195 NKGIDSDASYPYKAMDQKCQYDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVG 251
Query: 268 IDA--ADIVNYKQGI-IKYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+DA Y+ G+ + +NH VL+VGYG N YW KN+WG ++GE+G+ R
Sbjct: 252 VDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311
Query: 97 VQQNI-NACGM 68
+ +N N CG+
Sbjct: 312 MARNKGNHCGI 322
>AL356292-9|CAI13657.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 165 bits (401), Expect = 2e-40
Identities = 88/251 (35%), Positives = 141/251 (56%), Gaps = 10/251 (3%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E ++ + L +P+Q Q + P P DWR VT VK QG
Sbjct: 77 MNHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIK 440
CGACWAF+ +G+LE+Q +K +L++LS Q ++DC + + GCNGG + TAF+ II
Sbjct: 135 SCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIID 194
Query: 439 MGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMA 269
G+ ++ YPY+A + C+ +S + C +Y + Y E+ LK+ + GP+ +
Sbjct: 195 NKGIDSDASYPYKAMDQKCQYDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVG 251
Query: 268 IDA--ADIVNYKQGI-IKYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+DA Y+ G+ + +NH VL+VGYG N YW KN+WG ++GE+G+ R
Sbjct: 252 VDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311
Query: 97 VQQNI-NACGM 68
+ +N N CG+
Sbjct: 312 MARNKGNHCGI 322
>S93414-1|AAB22005.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 164 bits (399), Expect = 3e-40
Identities = 88/251 (35%), Positives = 140/251 (55%), Gaps = 10/251 (3%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E ++ + L +P+Q Q + P P DWR VT VK QG
Sbjct: 77 MNHLGDMTSEEVMSLTSSLRVPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIK 440
CGACWAF+ +G+LE+Q +K +L+ LS Q ++DC + + GCNGG + TAF+ II
Sbjct: 135 SCGACWAFSAVGALEAQLKLKTGKLVTLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIID 194
Query: 439 MGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMA 269
G+ ++ YPY+A + C+ +S + C +Y + Y E+ LK+ + GP+ +
Sbjct: 195 NKGIDSDASYPYKAMDQKCQYDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVG 251
Query: 268 IDA--ADIVNYKQGI-IKYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+DA Y+ G+ + +NH VL+VGYG N YW KN+WG ++GE+G+ R
Sbjct: 252 VDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311
Query: 97 VQQNI-NACGM 68
+ +N N CG+
Sbjct: 312 MARNKGNHCGI 322
>M86553-1|AAA35655.1| 331|Homo sapiens cathepsin protein.
Length = 331
Score = 164 bits (399), Expect = 3e-40
Identities = 88/251 (35%), Positives = 140/251 (55%), Gaps = 10/251 (3%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E ++ + L +P+Q Q + P P DWR VT VK QG
Sbjct: 77 MNHLGDMTSEEVMSLTSSLRVPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIK 440
CGACWAF+ +G+LE+Q +K +L+ LS Q ++DC + + GCNGG + TAF+ II
Sbjct: 135 SCGACWAFSAVGALEAQLKLKTGKLVTLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIID 194
Query: 439 MGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMA 269
G+ ++ YPY+A + C+ +S + C +Y + Y E+ LK+ + GP+ +
Sbjct: 195 NKGIDSDASYPYKAMDQKCQYDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVG 251
Query: 268 IDA--ADIVNYKQGI-IKYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+DA Y+ G+ + +NH VL+VGYG N YW KN+WG ++GE+G+ R
Sbjct: 252 VDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311
Query: 97 VQQNI-NACGM 68
+ +N N CG+
Sbjct: 312 MARNKGNHCGI 322
>M90696-1|AAC37592.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 164 bits (398), Expect = 4e-40
Identities = 88/251 (35%), Positives = 141/251 (56%), Gaps = 10/251 (3%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E ++ + L +P+Q Q + P P DWR VT VK QG
Sbjct: 77 MNHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIK 440
CGACWAF+ +G+LE+Q +K +L++LS Q ++DC + + GCNGG + TAF+ II
Sbjct: 135 SCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIID 194
Query: 439 MGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMA 269
G+ ++ YPY+A + C+ +S + C +Y + Y E+ LK+ + GP+ +
Sbjct: 195 NKGIDSDASYPYKAMDLKCQYDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVG 251
Query: 268 IDA--ADIVNYKQGI-IKYCFDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFR 98
+DA Y+ G+ + +NH VL+VGYG N YW KN+WG ++GE+G+ R
Sbjct: 252 VDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIR 311
Query: 97 VQQNI-NACGM 68
+ +N N CG+
Sbjct: 312 MARNKGNHCGI 322
>X12451-1|CAA30981.1| 333|Homo sapiens pro-(cathepsin L) protein.
Length = 333
Score = 161 bits (392), Expect = 2e-39
Identities = 87/213 (40%), Positives = 119/213 (55%), Gaps = 11/213 (5%)
Frame = -1
Query: 673 KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV 494
+ P DWR VT VKNQG CG+CWAF+ G+LE Q K LI+LSEQ ++DC
Sbjct: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172
Query: 493 --DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVY 320
+ GCNGGL+ AF+ + GG+ E YPYEA +C+ N K+ V + I
Sbjct: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQ 231
Query: 319 EEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSGLNHAVLLVGYGVE----N 164
E+ L + VGPI +AIDA + YK+GI C ++H VL+VGYG E +
Sbjct: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291
Query: 163 NIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>M20496-1|AAA66974.1| 333|Homo sapiens CTSL protein.
Length = 333
Score = 161 bits (392), Expect = 2e-39
Identities = 87/213 (40%), Positives = 119/213 (55%), Gaps = 11/213 (5%)
Frame = -1
Query: 673 KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV 494
+ P DWR VT VKNQG CG+CWAF+ G+LE Q K LI+LSEQ ++DC
Sbjct: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172
Query: 493 --DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVY 320
+ GCNGGL+ AF+ + GG+ E YPYEA +C+ N K+ V + I
Sbjct: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQ 231
Query: 319 EEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSGLNHAVLLVGYGVE----N 164
E+ L + VGPI +AIDA + YK+GI C ++H VL+VGYG E +
Sbjct: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291
Query: 163 NIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>CR457053-1|CAG33334.1| 333|Homo sapiens CTSL protein.
Length = 333
Score = 161 bits (392), Expect = 2e-39
Identities = 87/213 (40%), Positives = 119/213 (55%), Gaps = 11/213 (5%)
Frame = -1
Query: 673 KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV 494
+ P DWR VT VKNQG CG+CWAF+ G+LE Q K LI+LSEQ ++DC
Sbjct: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172
Query: 493 --DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVY 320
+ GCNGGL+ AF+ + GG+ E YPYEA +C+ N K+ V + I
Sbjct: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQ 231
Query: 319 EEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSGLNHAVLLVGYGVE----N 164
E+ L + VGPI +AIDA + YK+GI C ++H VL+VGYG E +
Sbjct: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291
Query: 163 NIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>BC012612-1|AAH12612.1| 333|Homo sapiens cathepsin L1 protein.
Length = 333
Score = 161 bits (392), Expect = 2e-39
Identities = 87/213 (40%), Positives = 119/213 (55%), Gaps = 11/213 (5%)
Frame = -1
Query: 673 KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV 494
+ P DWR VT VKNQG CG+CWAF+ G+LE Q K LI+LSEQ ++DC
Sbjct: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172
Query: 493 --DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVY 320
+ GCNGGL+ AF+ + GG+ E YPYEA +C+ N K+ V + I
Sbjct: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQ 231
Query: 319 EEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSGLNHAVLLVGYGVE----N 164
E+ L + VGPI +AIDA + YK+GI C ++H VL+VGYG E +
Sbjct: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291
Query: 163 NIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>AL160279-3|CAI16308.1| 333|Homo sapiens cathepsin L1 protein.
Length = 333
Score = 161 bits (392), Expect = 2e-39
Identities = 87/213 (40%), Positives = 119/213 (55%), Gaps = 11/213 (5%)
Frame = -1
Query: 673 KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV 494
+ P DWR VT VKNQG CG+CWAF+ G+LE Q K LI+LSEQ ++DC
Sbjct: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172
Query: 493 --DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVY 320
+ GCNGGL+ AF+ + GG+ E YPYEA +C+ N K+ V + I
Sbjct: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQ 231
Query: 319 EEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSGLNHAVLLVGYGVE----N 164
E+ L + VGPI +AIDA + YK+GI C ++H VL+VGYG E +
Sbjct: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291
Query: 163 NIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>BC142983-1|AAI42984.1| 333|Homo sapiens cathepsin L1 protein.
Length = 333
Score = 161 bits (390), Expect = 4e-39
Identities = 87/213 (40%), Positives = 119/213 (55%), Gaps = 11/213 (5%)
Frame = -1
Query: 673 KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV 494
+ P DWR VT VKNQG CG+CWAF+ G+LE Q K LI+LSEQ ++DC
Sbjct: 113 EAPRSVDWREKGYVTPVKNQGPCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172
Query: 493 --DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVY 320
+ GCNGGL+ AF+ + GG+ E YPYEA +C+ N K+ V + I
Sbjct: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQ 231
Query: 319 EEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSGLNHAVLLVGYGVE----N 164
E+ L + VGPI +AIDA + YK+GI C ++H VL+VGYG E +
Sbjct: 232 EKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESD 291
Query: 163 NIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 292 NNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>AL137742-1|CAB70900.1| 308|Homo sapiens hypothetical protein
protein.
Length = 308
Score = 153 bits (370), Expect = 1e-36
Identities = 82/215 (38%), Positives = 122/215 (56%), Gaps = 4/215 (1%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTS 626
+A+Y + KFSDL+++E Y L + N K+ P E+DWR VT
Sbjct: 68 TAQYGVTKFSDLTEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTK 125
Query: 625 VKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAI 446
VK+QGMCG+CWAF+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI
Sbjct: 126 VKDQGMCGSCWAFSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAI 185
Query: 445 IKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAI 266
+GG++ E DY Y+ +C ++ K V + D + E+KL L GPI +AI
Sbjct: 186 KNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVE-LSQNEQKLAAWLAKRGPISVAI 244
Query: 265 DAADIVNYKQGIIK----YCFDSGLNHAVLLVGYG 173
+A + Y+ GI + C ++HAVLLVGYG
Sbjct: 245 NAFGMQFYRHGISRPLRPLCSPWLIDHAVLLVGYG 279
>Y14734-1|CAA75029.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 151 bits (366), Expect = 3e-36
Identities = 83/214 (38%), Positives = 118/214 (55%), Gaps = 14/214 (6%)
Frame = -1
Query: 667 PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV-- 494
P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L++LSEQ ++DC
Sbjct: 115 PKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQG 174
Query: 493 DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEE 314
+ GCNGG + AF+ + + GG+ E YPY A + C+ V + + +V
Sbjct: 175 NQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN---SVANDTGFTVVAPG 231
Query: 313 KLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGLNHAVLLVGYGVE---- 167
K K L++ VGPI +A+DA + YK GI C L+H VL+VGYG E
Sbjct: 232 KEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANS 291
Query: 166 NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 292 NNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>BC110512-1|AAI10513.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 151 bits (366), Expect = 3e-36
Identities = 83/214 (38%), Positives = 118/214 (55%), Gaps = 14/214 (6%)
Frame = -1
Query: 667 PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV-- 494
P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L++LSEQ ++DC
Sbjct: 115 PKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQG 174
Query: 493 DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEE 314
+ GCNGG + AF+ + + GG+ E YPY A + C+ V + + +V
Sbjct: 175 NQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN---SVANDTGFTVVAPG 231
Query: 313 KLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGLNHAVLLVGYGVE---- 167
K K L++ VGPI +A+DA + YK GI C L+H VL+VGYG E
Sbjct: 232 KEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANS 291
Query: 166 NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 292 NNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>BC023504-1|AAH23504.1| 334|Homo sapiens CTSL2 protein protein.
Length = 334
Score = 151 bits (366), Expect = 3e-36
Identities = 83/214 (38%), Positives = 118/214 (55%), Gaps = 14/214 (6%)
Frame = -1
Query: 667 PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV-- 494
P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L++LSEQ ++DC
Sbjct: 115 PKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQG 174
Query: 493 DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEE 314
+ GCNGG + AF+ + + GG+ E YPY A + C+ V + + +V
Sbjct: 175 NQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN---SVANDTGFTVVAPG 231
Query: 313 KLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGLNHAVLLVGYGVE---- 167
K K L++ VGPI +A+DA + YK GI C L+H VL+VGYG E
Sbjct: 232 KEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANS 291
Query: 166 NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 292 NNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>AY358641-1|AAQ89004.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 151 bits (366), Expect = 3e-36
Identities = 83/214 (38%), Positives = 118/214 (55%), Gaps = 14/214 (6%)
Frame = -1
Query: 667 PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV-- 494
P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L++LSEQ ++DC
Sbjct: 115 PKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQG 174
Query: 493 DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEE 314
+ GCNGG + AF+ + + GG+ E YPY A + C+ V + + +V
Sbjct: 175 NQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN---SVANDTGFTVVAPG 231
Query: 313 KLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGLNHAVLLVGYGVE---- 167
K K L++ VGPI +A+DA + YK GI C L+H VL+VGYG E
Sbjct: 232 KEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANS 291
Query: 166 NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 292 NNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>AL445670-2|CAI15053.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 151 bits (366), Expect = 3e-36
Identities = 83/214 (38%), Positives = 118/214 (55%), Gaps = 14/214 (6%)
Frame = -1
Query: 667 PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV-- 494
P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L++LSEQ ++DC
Sbjct: 115 PKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQG 174
Query: 493 DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEE 314
+ GCNGG + AF+ + + GG+ E YPY A + C+ V + + +V
Sbjct: 175 NQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN---SVANDTGFTVVAPG 231
Query: 313 KLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGLNHAVLLVGYGVE---- 167
K K L++ VGPI +A+DA + YK GI C L+H VL+VGYG E
Sbjct: 232 KEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANS 291
Query: 166 NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 292 NNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>AF070448-1|AAC23598.1| 334|Homo sapiens cathepsin U protein.
Length = 334
Score = 151 bits (366), Expect = 3e-36
Identities = 83/214 (38%), Positives = 118/214 (55%), Gaps = 14/214 (6%)
Frame = -1
Query: 667 PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV-- 494
P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L++LSEQ ++DC
Sbjct: 115 PKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQG 174
Query: 493 DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEE 314
+ GCNGG + AF+ + + GG+ E YPY A + C+ V + + +V
Sbjct: 175 NQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN---SVANDTGFTVVAPG 231
Query: 313 KLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGLNHAVLLVGYGVE---- 167
K K L++ VGPI +A+DA + YK GI C L+H VL+VGYG E
Sbjct: 232 KEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANS 291
Query: 166 NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 292 NNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>AB019534-1|BAA34365.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 151 bits (366), Expect = 3e-36
Identities = 83/214 (38%), Positives = 118/214 (55%), Gaps = 14/214 (6%)
Frame = -1
Query: 667 PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV-- 494
P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L++LSEQ ++DC
Sbjct: 115 PKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQG 174
Query: 493 DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEE 314
+ GCNGG + AF+ + + GG+ E YPY A + C+ V + + +V
Sbjct: 175 NQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN---SVANDTGFTVVAPG 231
Query: 313 KLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGLNHAVLLVGYGVE---- 167
K K L++ VGPI +A+DA + YK GI C L+H VL+VGYG E
Sbjct: 232 KEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANS 291
Query: 166 NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 292 NNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>AB001928-1|BAA25909.1| 334|Homo sapiens cathepsin V protein.
Length = 334
Score = 151 bits (366), Expect = 3e-36
Identities = 83/214 (38%), Positives = 118/214 (55%), Gaps = 14/214 (6%)
Frame = -1
Query: 667 PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV-- 494
P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L++LSEQ ++DC
Sbjct: 115 PKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQG 174
Query: 493 DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEE 314
+ GCNGG + AF+ + + GG+ E YPY A + C+ V + + +V
Sbjct: 175 NQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN---SVANDTGFTVVAPG 231
Query: 313 KLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGLNHAVLLVGYGVE---- 167
K K L++ VGPI +A+DA + YK GI C L+H VL+VGYG E
Sbjct: 232 KEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANS 291
Query: 166 NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 68
NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 292 NNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>Y18461-1|CAA77179.1| 166|Homo sapiens cathepsin H protein.
Length = 166
Score = 134 bits (325), Expect = 3e-31
Identities = 68/166 (40%), Positives = 95/166 (57%), Gaps = 7/166 (4%)
Frame = -1
Query: 607 CGACWAFATLGSLESQFAIKHNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMG 434
CG+CW F+T G+LES AI ++++L+EQQ++DC DF + GC GGL AFE I+
Sbjct: 1 CGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNK 60
Query: 433 GVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA- 257
G+ E YPY+ + C+ K + VKD I EE + + + L P+ A +
Sbjct: 61 GIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQ 120
Query: 256 DIVNYKQGIIK--YCFDS--GLNHAVLLVGYGVENNIPYWTFKNTW 131
D + Y+ GI C + +NHAVL VGYG EN IPYW KN+W
Sbjct: 121 DFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEENGIPYWIVKNSW 166
>BC048255-1|AAH48255.1| 376|Homo sapiens cathepsin W protein.
Length = 376
Score = 133 bits (322), Expect = 6e-31
Identities = 77/273 (28%), Positives = 136/273 (49%), Gaps = 27/273 (9%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVT 629
+A++ + FSDL+++E Y + + I ++P P DWR++ ++
Sbjct: 83 TAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAIS 142
Query: 628 SVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEA 449
+K+Q C CWA A G++E+ + I + +++S Q+++DC GC+GG + AF
Sbjct: 143 PIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRCGDGCHGGFVWDAFIT 202
Query: 448 IIKMGGVQLESDYPYEADNNNCRMNSNKF--LVQVKDCYRYIIVYEEKLKDLLRLVGPIP 275
++ G+ E DYP++ R + K+ + ++D + + E ++ L GPI
Sbjct: 203 VLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQD-FIMLQNNEHRIAQYLATYGPIT 261
Query: 274 MAIDAADIVNYKQGIIK----YCFDSGLNHAVLLVGYG---VENNI-------------- 158
+ I+ + Y++G+IK C ++H+VLLVG+G E I
Sbjct: 262 VTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPP 321
Query: 157 ---PYWTFKNTWGTDWGEDGFFRVQQNINACGM 68
PYW KN+WG WGE G+FR+ + N CG+
Sbjct: 322 HPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGI 354
>Y18462-1|CAA77180.1| 175|Homo sapiens cathepsin L protein.
Length = 175
Score = 132 bits (318), Expect = 2e-30
Identities = 75/176 (42%), Positives = 99/176 (56%), Gaps = 10/176 (5%)
Frame = -1
Query: 634 VTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV--DAGCNGGLLHT 461
VT VKNQG CG+CWAF+ G+LE Q K LI+LSEQ ++DC + GCNGGL+
Sbjct: 1 VTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDY 60
Query: 460 AFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGP 281
AF+ + GG+ E YPYEA +C+ N K+ V + I E+ L + VGP
Sbjct: 61 AFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQEKALMKAVATVGP 119
Query: 280 IPMAIDAA--DIVNYKQGII--KYCFDSGLNHAVLLVGYGVE----NNIPYWTFKN 137
I +AIDA + YK+GI C ++H VL+VGYG E +N YW KN
Sbjct: 120 ISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESSESDNNKYWLVKN 175
>AF055903-1|AAC32181.1| 376|Homo sapiens cathepsin W protein.
Length = 376
Score = 131 bits (317), Expect = 3e-30
Identities = 76/273 (27%), Positives = 135/273 (49%), Gaps = 27/273 (9%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVT 629
+A++ + FSDL+++E Y + + I ++P P DWR++ ++
Sbjct: 83 TAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAIS 142
Query: 628 SVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEA 449
+K+Q C CWA A G++E+ + I + +++S +++DC GC+GG + AF
Sbjct: 143 PIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVHELLDCGRCGDGCHGGFVWDAFIT 202
Query: 448 IIKMGGVQLESDYPYEADNNNCRMNSNKF--LVQVKDCYRYIIVYEEKLKDLLRLVGPIP 275
++ G+ E DYP++ R + K+ + ++D + + E ++ L GPI
Sbjct: 203 VLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQD-FIMLQNNEHRIAQYLATYGPIT 261
Query: 274 MAIDAADIVNYKQGIIK----YCFDSGLNHAVLLVGYG---VENNI-------------- 158
+ I+ + Y++G+IK C ++H+VLLVG+G E I
Sbjct: 262 VTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPP 321
Query: 157 ---PYWTFKNTWGTDWGEDGFFRVQQNINACGM 68
PYW KN+WG WGE G+FR+ + N CG+
Sbjct: 322 HPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGI 354
>AF015954-1|AAB82457.1| 376|Homo sapiens lymphopain protein.
Length = 376
Score = 131 bits (317), Expect = 3e-30
Identities = 76/273 (27%), Positives = 135/273 (49%), Gaps = 27/273 (9%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVT 629
+A++ + FSDL+++E Y + + I ++P P DWR++ ++
Sbjct: 83 TAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAIS 142
Query: 628 SVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEA 449
+K+Q C CWA A G++E+ + I + +++S +++DC GC+GG + AF
Sbjct: 143 PIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVHELLDCGRCGDGCHGGFVWDAFIT 202
Query: 448 IIKMGGVQLESDYPYEADNNNCRMNSNKF--LVQVKDCYRYIIVYEEKLKDLLRLVGPIP 275
++ G+ E DYP++ R + K+ + ++D + + E ++ L GPI
Sbjct: 203 VLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQD-FIMLQNNEHRIAQYLATYGPIT 261
Query: 274 MAIDAADIVNYKQGIIK----YCFDSGLNHAVLLVGYG---VENNI-------------- 158
+ I+ + Y++G+IK C ++H+VLLVG+G E I
Sbjct: 262 VTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPP 321
Query: 157 ---PYWTFKNTWGTDWGEDGFFRVQQNINACGM 68
PYW KN+WG WGE G+FR+ + N CG+
Sbjct: 322 HPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGI 354
>AF013611-1|AAB82449.1| 376|Homo sapiens lymphopain protein.
Length = 376
Score = 131 bits (317), Expect = 3e-30
Identities = 76/273 (27%), Positives = 135/273 (49%), Gaps = 27/273 (9%)
Frame = -1
Query: 805 SAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVT 629
+A++ + FSDL+++E Y + + I ++P P DWR++ ++
Sbjct: 83 TAEFGVTPFSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAIS 142
Query: 628 SVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEA 449
+K+Q C CWA A G++E+ + I + +++S +++DC GC+GG + AF
Sbjct: 143 PIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVHELLDCGRCGDGCHGGFVWDAFIT 202
Query: 448 IIKMGGVQLESDYPYEADNNNCRMNSNKF--LVQVKDCYRYIIVYEEKLKDLLRLVGPIP 275
++ G+ E DYP++ R + K+ + ++D + + E ++ L GPI
Sbjct: 203 VLNNSGLASEKDYPFQGKVRAHRCHPKKYQKVAWIQD-FIMLQNNEHRIAQYLATYGPIT 261
Query: 274 MAIDAADIVNYKQGIIK----YCFDSGLNHAVLLVGYG---VENNI-------------- 158
+ I+ + Y++G+IK C ++H+VLLVG+G E I
Sbjct: 262 VTINMKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPP 321
Query: 157 ---PYWTFKNTWGTDWGEDGFFRVQQNINACGM 68
PYW KN+WG WGE G+FR+ + N CG+
Sbjct: 322 HPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGI 354
>X87212-1|CAA60671.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 120 bits (289), Expect = 6e-27
Identities = 74/230 (32%), Positives = 124/230 (53%), Gaps = 21/230 (9%)
Frame = -1
Query: 667 PLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDC 503
P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N LS Q+++ C
Sbjct: 232 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 291
Query: 502 DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIV 323
GC GG + + G+ E+ +PY ++ C+M + F + Y Y+
Sbjct: 292 SQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSE-YHYVGG 350
Query: 322 YEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC-----FDSG--LNHAVLLV 182
+ + L LV GP+ +A + D ++YK+GI + F+ NHAVLLV
Sbjct: 351 FYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLV 410
Query: 181 GYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELASTAV 41
GYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A+T +
Sbjct: 411 GYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>U79415-1|AAC51341.1| 463|Homo sapiens prepro dipeptidyl peptidase
I protein.
Length = 463
Score = 120 bits (289), Expect = 6e-27
Identities = 74/230 (32%), Positives = 124/230 (53%), Gaps = 21/230 (9%)
Frame = -1
Query: 667 PLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDC 503
P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N LS Q+++ C
Sbjct: 232 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 291
Query: 502 DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIV 323
GC GG + + G+ E+ +PY ++ C+M + F + Y Y+
Sbjct: 292 SQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSE-YHYVGG 350
Query: 322 YEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC-----FDSG--LNHAVLLV 182
+ + L LV GP+ +A + D ++YK+GI + F+ NHAVLLV
Sbjct: 351 FYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLV 410
Query: 181 GYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELASTAV 41
GYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A+T +
Sbjct: 411 GYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>U07374-1|AAB60643.2| 267|Homo sapiens cathepsin S protein.
Length = 267
Score = 120 bits (289), Expect = 6e-27
Identities = 63/183 (34%), Positives = 102/183 (55%), Gaps = 6/183 (3%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E ++ + L +P+Q Q + P P DWR VT VK QG
Sbjct: 77 MNHLGDMTSEEVMSLTSSLRVPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQG 134
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIK 440
CGACWAF+ +G+LE+Q +K +L+ LS Q ++DC + + GCNGG + TAF+ II
Sbjct: 135 SCGACWAFSAVGALEAQLKLKTGKLVTLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIID 194
Query: 439 MGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMA 269
G+ ++ YPY+A + C+ +S + C +Y + Y E+ LK+ + GP+ +
Sbjct: 195 NKGIDSDASYPYKAMDQKCQYDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVG 251
Query: 268 IDA 260
+DA
Sbjct: 252 VDA 254
>AK223038-1|BAD96758.1| 463|Homo sapiens cathepsin C isoform a
preproprotein variant protein.
Length = 463
Score = 120 bits (289), Expect = 6e-27
Identities = 74/230 (32%), Positives = 124/230 (53%), Gaps = 21/230 (9%)
Frame = -1
Query: 667 PLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDC 503
P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N LS Q+++ C
Sbjct: 232 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 291
Query: 502 DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIV 323
GC GG + + G+ E+ +PY ++ C+M + F + Y Y+
Sbjct: 292 SQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSE-YHYVGG 350
Query: 322 YEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC-----FDSG--LNHAVLLV 182
+ + L LV GP+ +A + D ++YK+GI + F+ NHAVLLV
Sbjct: 351 FYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLV 410
Query: 181 GYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELASTAV 41
GYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A+T +
Sbjct: 411 GYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>AF234263-1|AAL48191.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 120 bits (289), Expect = 6e-27
Identities = 74/230 (32%), Positives = 124/230 (53%), Gaps = 21/230 (9%)
Frame = -1
Query: 667 PLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDC 503
P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N LS Q+++ C
Sbjct: 232 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 291
Query: 502 DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIV 323
GC GG + + G+ E+ +PY ++ C+M + F + Y Y+
Sbjct: 292 SQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSE-YHYVGG 350
Query: 322 YEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC-----FDSG--LNHAVLLV 182
+ + L LV GP+ +A + D ++YK+GI + F+ NHAVLLV
Sbjct: 351 FYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLV 410
Query: 181 GYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELASTAV 41
GYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A+T +
Sbjct: 411 GYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>AF525032-1|AAQ08887.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 119 bits (287), Expect = 1e-26
Identities = 74/230 (32%), Positives = 124/230 (53%), Gaps = 21/230 (9%)
Frame = -1
Query: 667 PLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDC 503
P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N LS Q+++ C
Sbjct: 232 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 291
Query: 502 DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIV 323
GC GG + + G+ E+ +PY ++ C+M + F + Y Y+
Sbjct: 292 SQHAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSE-YHYVGG 350
Query: 322 YEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC-----FDSG--LNHAVLLV 182
+ + L LV GP+ +A + D ++YK+GI + F+ NHAVLLV
Sbjct: 351 FYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLV 410
Query: 181 GYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELASTAV 41
GYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A+T +
Sbjct: 411 GYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>AF234264-1|AAL48192.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 116 bits (280), Expect = 8e-26
Identities = 73/230 (31%), Positives = 123/230 (53%), Gaps = 21/230 (9%)
Frame = -1
Query: 667 PLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDC 503
P + WR +N V+ V+NQ CG+C++FA++G LE++ I N LS Q+++ C
Sbjct: 232 PTSWYWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSC 291
Query: 502 DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIV 323
GC GG + + G+ E+ +PY ++ C+M + F + Y Y+
Sbjct: 292 SQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSE-YHYVGG 350
Query: 322 YEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC-----FDSG--LNHAVLLV 182
+ + L LV GP+ +A + D ++YK+GI + F+ NHAVLLV
Sbjct: 351 FYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLV 410
Query: 181 GYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELASTAV 41
GYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A+T +
Sbjct: 411 GYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>AF254757-1|AAL48195.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 116 bits (278), Expect = 1e-25
Identities = 73/230 (31%), Positives = 123/230 (53%), Gaps = 21/230 (9%)
Frame = -1
Query: 667 PLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDC 503
P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N LS Q+++
Sbjct: 232 PTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSY 291
Query: 502 DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIV 323
GC GG + + G+ E+ +PY ++ C+M + F + Y Y+
Sbjct: 292 SQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSE-YHYVGG 350
Query: 322 YEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC-----FDSG--LNHAVLLV 182
+ + L LV GP+ +A + D ++YK+GI + F+ NHAVLLV
Sbjct: 351 FYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLV 410
Query: 181 GYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELASTAV 41
GYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A+T +
Sbjct: 411 GYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>AL355860-2|CAI12796.1| 258|Homo sapiens cathepsin K protein.
Length = 258
Score = 105 bits (251), Expect = 3e-22
Identities = 46/124 (37%), Positives = 72/124 (58%)
Frame = -1
Query: 790 INKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQG 611
+N D++ +E + K TGL +P + + + G+ P D+R+ VT VKNQG
Sbjct: 134 MNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQG 193
Query: 610 MCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGG 431
CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ + K G
Sbjct: 194 QCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRG 253
Query: 430 VQLE 419
+ E
Sbjct: 254 IDSE 257
>AL160279-2|CAI16307.1| 225|Homo sapiens cathepsin L1 protein.
Length = 225
Score = 101 bits (242), Expect = 3e-21
Identities = 49/108 (45%), Positives = 64/108 (59%), Gaps = 4/108 (3%)
Frame = -1
Query: 673 KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV 494
+ P DWR VT VKNQG CG+CWAF+ G+LE Q K LI+LSEQ ++DC
Sbjct: 113 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGP 172
Query: 493 --DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNN--CRMNSNKF 362
+ GCNGGL+ AF+ + GG+ E YPYEA + C +S+ F
Sbjct: 173 QGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATVSGAPCHHSSSAF 220
>AF217997-1|AAG17239.1| 151|Homo sapiens unknown protein.
Length = 151
Score = 86.6 bits (205), Expect = 1e-16
Identities = 51/140 (36%), Positives = 74/140 (52%), Gaps = 9/140 (6%)
Frame = -1
Query: 460 AFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGP 281
AF+ + GG+ E YPYEA +C+ N K+ V + I E+ L + VGP
Sbjct: 4 AFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQEKALMKAVATVGP 62
Query: 280 IPMAIDAA--DIVNYKQGII--KYCFDSGLNHAVLLVGYGVEN----NIPYWTFKNTWGT 125
I +AIDA + YK+GI C ++H VL+VGYG E+ N YW KN+WG
Sbjct: 63 ISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGE 122
Query: 124 DWGEDGFFRV-QQNINACGM 68
+WG G+ ++ + N CG+
Sbjct: 123 EWGMGGYVKMAKDRRNHCGI 142
>BT019915-1|AAV38718.1| 303|Homo sapiens cathepsin Z protein.
Length = 303
Score = 79.4 bits (187), Expect = 1e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -1
Query: 679 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 527
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 526 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 353
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 352 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 215
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 214 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 95
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>BC042168-1|AAH42168.1| 303|Homo sapiens cathepsin Z protein.
Length = 303
Score = 79.4 bits (187), Expect = 1e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -1
Query: 679 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 527
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 526 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 353
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 352 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 215
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 214 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 95
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>AL109840-6|CAC09370.1| 303|Homo sapiens cathepsin Z protein.
Length = 303
Score = 79.4 bits (187), Expect = 1e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -1
Query: 679 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 527
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 526 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 353
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 352 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 215
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 214 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 95
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>AF136276-1|AAF13148.1| 303|Homo sapiens cathepsin Z precursor
protein.
Length = 303
Score = 79.4 bits (187), Expect = 1e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -1
Query: 679 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 527
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 526 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 353
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 352 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 215
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 214 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 95
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>AF136273-1|AAF13145.1| 303|Homo sapiens cathepsin Z precursor
protein.
Length = 303
Score = 79.4 bits (187), Expect = 1e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -1
Query: 679 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 527
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 526 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 353
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 352 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 215
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 214 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 95
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>AF032906-1|AAC39839.1| 303|Homo sapiens cathepsin Z precursor
protein.
Length = 303
Score = 79.4 bits (187), Expect = 1e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -1
Query: 679 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 527
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 526 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 353
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 352 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 215
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 214 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 95
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>AF009923-1|AAC63141.1| 293|Homo sapiens preprocathepsin P protein.
Length = 293
Score = 79.4 bits (187), Expect = 1e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -1
Query: 679 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 527
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 49 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 108
Query: 526 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 353
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 109 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 165
Query: 352 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 215
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 166 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 225
Query: 214 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 95
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 226 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 265
>AF073890-1|AAC61477.1| 303|Homo sapiens cathepsin X precursor
protein.
Length = 303
Score = 78.6 bits (185), Expect = 3e-14
Identities = 61/219 (27%), Positives = 100/219 (45%), Gaps = 24/219 (10%)
Frame = -1
Query: 679 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 527
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 526 SEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQV 350
S Q +IDC C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCGN-RGSCEGGNDLSVWD-YAHQHGISDETCNNYQAKDQECDKFNQCGTCNEF 176
Query: 349 KDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCFD 212
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 177 KECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDT 236
Query: 211 SGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 95
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 237 TYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>M14221-1|AAA52129.1| 339|Homo sapiens CTSB protein.
Length = 339
Score = 74.1 bits (174), Expect = 6e-13
Identities = 29/81 (35%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 286 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTWGTDWGE 113
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W TDWG+
Sbjct: 247 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 306
Query: 112 DGFFRVQQNINACGMRNELAS 50
+GFF++ + + CG+ +E+ +
Sbjct: 307 NGFFKILRGQDHCGIESEVVA 327
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = -1
Query: 673 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 512
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 511 IDC--DFVDAGCNGG 473
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>M13230-1|AAA52125.1| 209|Homo sapiens CTSB protein.
Length = 209
Score = 74.1 bits (174), Expect = 6e-13
Identities = 29/81 (35%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 286 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTWGTDWGE 113
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W TDWG+
Sbjct: 117 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 176
Query: 112 DGFFRVQQNINACGMRNELAS 50
+GFF++ + + CG+ +E+ +
Sbjct: 177 NGFFKILRGQDHCGIESEVVA 197
>L16510-1|AAC37547.1| 339|Homo sapiens cathepsin B protein.
Length = 339
Score = 74.1 bits (174), Expect = 6e-13
Identities = 29/81 (35%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 286 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTWGTDWGE 113
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W TDWG+
Sbjct: 247 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 306
Query: 112 DGFFRVQQNINACGMRNELAS 50
+GFF++ + + CG+ +E+ +
Sbjct: 307 NGFFKILRGQDHCGIESEVVA 327
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = -1
Query: 673 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 512
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 511 IDC--DFVDAGCNGG 473
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>BC095408-1|AAH95408.1| 339|Homo sapiens cathepsin B protein.
Length = 339
Score = 74.1 bits (174), Expect = 6e-13
Identities = 29/81 (35%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 286 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTWGTDWGE 113
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W TDWG+
Sbjct: 247 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 306
Query: 112 DGFFRVQQNINACGMRNELAS 50
+GFF++ + + CG+ +E+ +
Sbjct: 307 NGFFKILRGQDHCGIESEVVA 327
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = -1
Query: 673 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 512
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 511 IDC--DFVDAGCNGG 473
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>BC010240-1|AAH10240.1| 339|Homo sapiens cathepsin B protein.
Length = 339
Score = 74.1 bits (174), Expect = 6e-13
Identities = 29/81 (35%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -1
Query: 286 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTWGTDWGE 113
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W TDWG+
Sbjct: 247 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 306
Query: 112 DGFFRVQQNINACGMRNELAS 50
+GFF++ + + CG+ +E+ +
Sbjct: 307 NGFFKILRGQDHCGIESEVVA 327
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = -1
Query: 673 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 512
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 511 IDC--DFVDAGCNGG 473
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>BC025419-1|AAH25419.1| 297|Homo sapiens CTSZ protein protein.
Length = 297
Score = 69.7 bits (163), Expect = 1e-11
Identities = 59/212 (27%), Positives = 97/212 (45%), Gaps = 25/212 (11%)
Frame = -1
Query: 679 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 527
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 526 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 353
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 352 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 215
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 214 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDW 119
+ +NH V + G+G+ + YW +N+WG W
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPW 267
>BC070278-1|AAH70278.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 61.3 bits (142), Expect = 4e-09
Identities = 61/222 (27%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Frame = -1
Query: 619 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 449
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 448 IIKMGGVQLESDYPY----EADNNNCRMNS--------------------NKFLVQVKDC 341
+ K G V + YP A NN C M S + + Q
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPP 354
Query: 340 YRYIIVYEEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYCFDSGLN---------HAV 191
YR E +K++++ GP+ + D +YK GI ++ + HAV
Sbjct: 355 YRVSSNETEIMKEIMQN-GPVQAIMQVHEDFFHYKTGIYRHVTSTNKESEKYRKLQTHAV 413
Query: 190 LLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 80
L G+G +W N+WG WGE+G+FR+ + +N
Sbjct: 414 KLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455
>BC064633-1|AAH64633.1| 467|Homo sapiens tubulointerstitial nephritis
antigen-like 1 protein.
Length = 467
Score = 61.3 bits (142), Expect = 4e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -1
Query: 781 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 611
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 610 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 440
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 439 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 323
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 322 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 191
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 190 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 62
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AY358421-1|AAQ88787.1| 467|Homo sapiens LCN7 protein.
Length = 467
Score = 61.3 bits (142), Expect = 4e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -1
Query: 781 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 611
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 610 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 440
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 439 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 323
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 322 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 191
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 190 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 62
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AL589946-2|CAH70302.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 61.3 bits (142), Expect = 4e-09
Identities = 61/222 (27%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Frame = -1
Query: 619 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 449
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 448 IIKMGGVQLESDYPY----EADNNNCRMNS--------------------NKFLVQVKDC 341
+ K G V + YP A NN C M S + + Q
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPP 354
Query: 340 YRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKYCFDSGLN---------HAV 191
YR E +K++++ GP+ + D +YK GI ++ + HAV
Sbjct: 355 YRVSSNETEIMKEIMQN-GPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAV 413
Query: 190 LLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 80
L G+G +W N+WG WGE+G+FR+ + +N
Sbjct: 414 KLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455
>AL359380-5|CAI16272.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 61.3 bits (142), Expect = 4e-09
Identities = 61/222 (27%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Frame = -1
Query: 619 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 449
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 448 IIKMGGVQLESDYPY----EADNNNCRMNS--------------------NKFLVQVKDC 341
+ K G V + YP A NN C M S + + Q
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPP 354
Query: 340 YRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKYCFDSGLN---------HAV 191
YR E +K++++ GP+ + D +YK GI ++ + HAV
Sbjct: 355 YRVSSNETEIMKEIMQN-GPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAV 413
Query: 190 LLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 80
L G+G +W N+WG WGE+G+FR+ + +N
Sbjct: 414 KLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455
>AK075398-1|BAC11596.1| 467|Homo sapiens protein ( Homo sapiens cDNA
PSEC0088 fis, clone PLACE1001098, highly similar to
P3ECSL; glucocorticoid-inducible protein. ).
Length = 467
Score = 61.3 bits (142), Expect = 4e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -1
Query: 781 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 611
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 610 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 440
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 439 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 323
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 322 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 191
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 190 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 62
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AF236155-1|AAG40154.1| 467|Homo sapiens tubulointerstitial nephritis
antigen-related protein protein.
Length = 467
Score = 61.3 bits (142), Expect = 4e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -1
Query: 781 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 611
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 610 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 440
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 439 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 323
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 322 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 191
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 190 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 62
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AF236150-1|AAG38876.1| 467|Homo sapiens tubulointerstitial nephritis
antigen-related protein precursor protein.
Length = 467
Score = 61.3 bits (142), Expect = 4e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -1
Query: 781 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 611
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 610 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 440
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 439 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 323
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 322 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 191
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 190 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 62
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AF205436-1|AAG33699.1| 467|Homo sapiens oxidized-LDL responsive gene
2 protein.
Length = 467
Score = 61.3 bits (142), Expect = 4e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -1
Query: 781 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 611
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 610 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 440
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 439 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 323
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 322 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 191
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 190 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 62
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AB050719-1|BAB18727.1| 467|Homo sapiens glucocorticoid-inducible
protein protein.
Length = 467
Score = 61.3 bits (142), Expect = 4e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -1
Query: 781 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 611
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 610 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 440
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 439 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 323
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 322 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 191
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 190 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 62
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AB050716-1|BAB18636.1| 467|Homo sapiens glucocorticoid-inducible
protein protein.
Length = 467
Score = 61.3 bits (142), Expect = 4e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -1
Query: 781 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 611
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 610 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 440
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 439 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 323
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 322 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 191
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 190 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 62
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AB022277-1|BAA84949.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 61.3 bits (142), Expect = 4e-09
Identities = 61/222 (27%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Frame = -1
Query: 619 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 449
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 448 IIKMGGVQLESDYPY----EADNNNCRMNS--------------------NKFLVQVKDC 341
+ K G V + YP A NN C M S + + Q
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPP 354
Query: 340 YRYIIVYEEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYCFDSGLN---------HAV 191
YR E +K++++ GP+ + D +YK GI ++ + HAV
Sbjct: 355 YRVSSNETEIMKEIMQN-GPVQAIMQVHEDFFHYKTGIYRHVTSTNKESEKYRKLQTHAV 413
Query: 190 LLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 80
L G+G +W N+WG WGE+G+FR+ + +N
Sbjct: 414 KLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455
>AF195116-1|AAF08931.1| 476|Homo sapiens tubulointerstitial
nephritis antigen isoform TIN-ag protein.
Length = 476
Score = 60.1 bits (139), Expect = 1e-08
Identities = 61/222 (27%), Positives = 90/222 (40%), Gaps = 42/222 (18%)
Frame = -1
Query: 619 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 449
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 448 IIKMGGVQLESDYPY----EADNNNCRMNS--------------------NKFLVQVKDC 341
+ K G V + YP A NN C M S + + Q
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMASRSDGRGKRDATKPCPNNVEKSNRIYQCSPP 354
Query: 340 YRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKYCFDSGLN---------HAV 191
YR E +K++++ GP+ + D +YK GI ++ + HAV
Sbjct: 355 YRVSSNETEIMKEIMQN-GPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAV 413
Query: 190 LLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 80
L G+G +W N WG WGE+G+FR+ + +N
Sbjct: 414 KLTGWGTLRGAQGQKEKFWIAANFWGKSWGENGYFRILRGVN 455
>X05256-1|CAA28877.1| 42|Homo sapiens protein ( Human mRNA
fragment for cathepsin L N-terminal/fragment. ).
Length = 42
Score = 54.0 bits (124), Expect = 6e-07
Identities = 21/38 (55%), Positives = 25/38 (65%)
Frame = -1
Query: 673 KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQ 560
+ P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQ 38
>BC009048-1|AAH09048.1| 218|Homo sapiens TINAGL1 protein protein.
Length = 218
Score = 51.2 bits (117), Expect = 4e-06
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 15/124 (12%)
Frame = -1
Query: 388 NCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC-- 218
N +N+N + QV YR +E +K+L+ GP+ ++ D YK GI +
Sbjct: 80 NSYVNNND-IYQVTPVYRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPV 137
Query: 217 -------FDSGLNHAVLLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINAC 74
+ H+V + G+G E + YWT N+WG WGE G FR+ + +N C
Sbjct: 138 SLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNEC 197
Query: 73 GMRN 62
+ +
Sbjct: 198 DIES 201
>AK027839-1|BAB55403.1| 218|Homo sapiens protein ( Homo sapiens
cDNA FLJ14933 fis, clone PLACE1009861, weakly similar to
CATHEPSIN B-LIKE CYSTEINE PROTEINASE 6 PRECURSOR (EC
3.4.22.-). ).
Length = 218
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 15/124 (12%)
Frame = -1
Query: 388 NCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC-- 218
N +N+N + QV YR +E +K+L+ GP+ ++ D Y+ GI +
Sbjct: 80 NSYVNNND-IYQVTPVYRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYEGGIYSHTPV 137
Query: 217 -------FDSGLNHAVLLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINAC 74
+ H+V + G+G E + YWT N+WG WGE G FR+ + +N C
Sbjct: 138 SLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNEC 197
Query: 73 GMRN 62
+ +
Sbjct: 198 DIES 201
>Y18460-1|CAA77178.1| 195|Homo sapiens cathepsin B protein.
Length = 195
Score = 44.8 bits (101), Expect = 4e-04
Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Frame = -1
Query: 286 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTW 131
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W
Sbjct: 141 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 194
Score = 39.9 bits (89), Expect = 0.011
Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Frame = -1
Query: 607 CGACWAFATLGSLESQFAIKHNELINLSEQQMIDC--DFVDAGCNGG 473
CG+CWAF + ++ + I N + +S + ++ C GCNGG
Sbjct: 1 CGSCWAFGAVEAISDRICIHTNVSVEVSAEDLLTCCGSMCGDGCNGG 47
>AL589946-1|CAH70301.1| 155|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 155
Score = 44.8 bits (101), Expect = 4e-04
Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 15/113 (13%)
Frame = -1
Query: 373 SNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKYCFDSGLN- 200
SN+ + Q YR E +K++++ GP+ + D +YK GI ++ +
Sbjct: 24 SNR-IYQCSPPYRVSSNETEIMKEIMQN-GPVQAIMQVREDFFHYKTGIYRHVTSTNKES 81
Query: 199 --------HAVLLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 80
HAV L G+G +W N+WG WGE+G+FR+ + +N
Sbjct: 82 EKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 134
>AF195117-1|AAF08932.1| 333|Homo sapiens tubulointerstitial
nephritis antigen isoform TIN2 protein.
Length = 333
Score = 44.8 bits (101), Expect = 4e-04
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 15/113 (13%)
Frame = -1
Query: 373 SNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKYCFDSGLN- 200
SN+ + Q YR E +K++++ GP+ + D +YK GI ++ +
Sbjct: 202 SNR-IYQCSPPYRVSSNETEIMKEIMQN-GPVQAIMQVREDFFHYKTGIYRHVTSTNKES 259
Query: 199 --------HAVLLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 80
HAV L G+G +W N WG WGE+G+FR+ + +N
Sbjct: 260 EKYRKLQTHAVKLTGWGTRRGAQGQKEKFWIAANFWGKSWGENGYFRILRGVN 312
>AK074124-1|BAB84950.1| 284|Homo sapiens FLJ00196 protein protein.
Length = 284
Score = 33.5 bits (73), Expect = 0.95
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 4/73 (5%)
Frame = -1
Query: 640 NKVTSVKNQGMCGACWAFATLGSLESQFAIK---HNELINLSEQQMIDCD-FVDAGCNGG 473
N + +QG C WAF+T + +I H + LS Q ++ CD GC GG
Sbjct: 81 NLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPV-LSPQNLLSCDTHQQQGCRGG 139
Query: 472 LLHTAFEAIIKMG 434
L A+ + + G
Sbjct: 140 RLDGAWWFLRRRG 152
>BC089428-1|AAH89428.1| 1192|Homo sapiens PLEKHG1 protein protein.
Length = 1192
Score = 30.7 bits (66), Expect = 6.7
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = -1
Query: 568 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 461
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1096 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1130
>AL450339-2|CAI12939.1| 1385|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 1
protein.
Length = 1385
Score = 30.7 bits (66), Expect = 6.7
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = -1
Query: 568 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 461
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1289 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1323
>AL035086-3|CAI42790.1| 1385|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 1
protein.
Length = 1385
Score = 30.7 bits (66), Expect = 6.7
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = -1
Query: 568 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 461
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1289 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1323
>AB033035-1|BAA86523.1| 1113|Homo sapiens KIAA1209 protein protein.
Length = 1113
Score = 30.7 bits (66), Expect = 6.7
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = -1
Query: 568 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 461
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1017 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1051
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,401,352
Number of Sequences: 237096
Number of extensions: 2479449
Number of successful extensions: 5810
Number of sequences better than 10.0: 102
Number of HSP's better than 10.0 without gapping: 5380
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5642
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10370898348
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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