Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmnc11c08
(901 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC036451-1|AAH36451.1| 484|Homo sapiens cathepsin F protein. 213 6e-55
BC011682-1|AAH11682.1| 484|Homo sapiens cathepsin F protein. 213 6e-55
AJ007331-1|CAB42883.1| 484|Homo sapiens cysteine proteinase pro... 213 6e-55
AF132894-1|AAD41790.1| 484|Homo sapiens cathepsin F protein. 213 6e-55
AF088886-1|AAD26616.2| 484|Homo sapiens cathepsin F precursor p... 213 6e-55
AF071749-1|AAC78839.1| 302|Homo sapiens cathepsin F protein. 213 6e-55
AF071748-1|AAC78838.1| 338|Homo sapiens cathepsin F protein. 213 6e-55
AF136279-1|AAF13146.1| 484|Homo sapiens cathepsin F precursor p... 212 2e-54
CR541680-1|CAG46481.1| 338|Homo sapiens CTSF protein. 210 4e-54
X16832-1|CAA34734.1| 335|Homo sapiens protein ( Human mRNA for ... 195 2e-49
CR456881-1|CAG33162.1| 335|Homo sapiens CTSH protein. 195 2e-49
BC002479-1|AAH02479.1| 335|Homo sapiens cathepsin H protein. 195 2e-49
AF426248-1|AAL23962.1| 323|Homo sapiens truncated cathepsin H p... 195 2e-49
AF426247-1|AAL23961.1| 335|Homo sapiens cathepsin H protein. 195 2e-49
X82153-1|CAA57649.1| 329|Homo sapiens Cathepsin O protein. 192 1e-48
U13665-1|AAA65233.1| 329|Homo sapiens cathepsin O protein. 192 1e-48
S79895-1|AAB35521.1| 329|Homo sapiens cathepsin O2 protein. 192 1e-48
CR541719-1|CAG46520.1| 329|Homo sapiens CTSK protein. 192 1e-48
CR541675-1|CAG46476.1| 329|Homo sapiens CTSK protein. 192 1e-48
BC016058-1|AAH16058.1| 329|Homo sapiens cathepsin K protein. 192 1e-48
AL356292-1|CAI13649.1| 329|Homo sapiens cathepsin K protein. 192 1e-48
AL355860-1|CAI12795.1| 329|Homo sapiens cathepsin K protein. 192 1e-48
U20280-1|AAA95998.1| 329|Homo sapiens cathepsin X protein. 190 8e-48
X77383-1|CAA54562.1| 321|Homo sapiens cathepsin O protein. 182 2e-45
BC049206-1|AAH49206.1| 321|Homo sapiens cathepsin O protein. 182 2e-45
X07549-1|CAA30428.1| 248|Homo sapiens cathepsin H protein. 176 1e-43
CR541676-1|CAG46477.1| 331|Homo sapiens CTSS protein. 170 5e-42
BC002642-1|AAH02642.1| 331|Homo sapiens cathepsin S protein. 170 5e-42
AL356292-9|CAI13657.1| 331|Homo sapiens cathepsin S protein. 170 5e-42
S93414-1|AAB22005.1| 331|Homo sapiens cathepsin S protein. 169 9e-42
M86553-1|AAA35655.1| 331|Homo sapiens cathepsin protein. 169 9e-42
M90696-1|AAC37592.1| 331|Homo sapiens cathepsin S protein. 169 1e-41
X12451-1|CAA30981.1| 333|Homo sapiens pro-(cathepsin L) protein. 163 6e-40
M20496-1|AAA66974.1| 333|Homo sapiens CTSL protein. 163 6e-40
CR457053-1|CAG33334.1| 333|Homo sapiens CTSL protein. 163 6e-40
AL160279-3|CAI16308.1| 333|Homo sapiens cathepsin L1 protein. 163 6e-40
BC012612-1|AAH12612.1| 333|Homo sapiens cathepsin L1 protein. 163 8e-40
BC142983-1|AAI42984.1| 333|Homo sapiens cathepsin L1 protein. 163 1e-39
AL137742-1|CAB70900.1| 308|Homo sapiens hypothetical protein pr... 161 3e-39
Y14734-1|CAA75029.1| 334|Homo sapiens cathepsin L2 protein. 153 1e-36
BC110512-1|AAI10513.1| 334|Homo sapiens cathepsin L2 protein. 152 1e-36
BC023504-1|AAH23504.1| 334|Homo sapiens CTSL2 protein protein. 152 1e-36
AY358641-1|AAQ89004.1| 334|Homo sapiens cathepsin L2 protein. 152 1e-36
AL445670-2|CAI15053.1| 334|Homo sapiens cathepsin L2 protein. 152 1e-36
AF070448-1|AAC23598.1| 334|Homo sapiens cathepsin U protein. 152 1e-36
AB019534-1|BAA34365.1| 334|Homo sapiens cathepsin L2 protein. 152 1e-36
AB001928-1|BAA25909.1| 334|Homo sapiens cathepsin V protein. 152 1e-36
BC048255-1|AAH48255.1| 376|Homo sapiens cathepsin W protein. 149 2e-35
AF055903-1|AAC32181.1| 376|Homo sapiens cathepsin W protein. 146 7e-35
AF015954-1|AAB82457.1| 376|Homo sapiens lymphopain protein. 146 7e-35
AF013611-1|AAB82449.1| 376|Homo sapiens lymphopain protein. 146 7e-35
Y18461-1|CAA77179.1| 166|Homo sapiens cathepsin H protein. 134 3e-31
Y18462-1|CAA77180.1| 175|Homo sapiens cathepsin L protein. 132 2e-30
U07374-1|AAB60643.2| 267|Homo sapiens cathepsin S protein. 125 2e-28
X87212-1|CAA60671.1| 463|Homo sapiens cathepsin C protein. 120 5e-27
U79415-1|AAC51341.1| 463|Homo sapiens prepro dipeptidyl peptida... 120 5e-27
AK223038-1|BAD96758.1| 463|Homo sapiens cathepsin C isoform a p... 120 5e-27
AF234263-1|AAL48191.1| 463|Homo sapiens cathepsin C protein. 120 5e-27
AF525032-1|AAQ08887.1| 463|Homo sapiens cathepsin C protein. 120 9e-27
AF234264-1|AAL48192.1| 463|Homo sapiens cathepsin C protein. 117 7e-26
AF254757-1|AAL48195.1| 463|Homo sapiens cathepsin C protein. 116 1e-25
AL355860-2|CAI12796.1| 258|Homo sapiens cathepsin K protein. 114 4e-25
AL160279-2|CAI16307.1| 225|Homo sapiens cathepsin L1 protein. 103 9e-22
AF217997-1|AAG17239.1| 151|Homo sapiens unknown protein. 87 1e-16
BT019915-1|AAV38718.1| 303|Homo sapiens cathepsin Z protein. 79 2e-14
BC042168-1|AAH42168.1| 303|Homo sapiens cathepsin Z protein. 79 2e-14
AL109840-6|CAC09370.1| 303|Homo sapiens cathepsin Z protein. 79 2e-14
AF136276-1|AAF13148.1| 303|Homo sapiens cathepsin Z precursor p... 79 2e-14
AF136273-1|AAF13145.1| 303|Homo sapiens cathepsin Z precursor p... 79 2e-14
AF032906-1|AAC39839.1| 303|Homo sapiens cathepsin Z precursor p... 79 2e-14
AF009923-1|AAC63141.1| 293|Homo sapiens preprocathepsin P protein. 79 2e-14
AF073890-1|AAC61477.1| 303|Homo sapiens cathepsin X precursor p... 79 3e-14
M14221-1|AAA52129.1| 339|Homo sapiens CTSB protein. 74 6e-13
M13230-1|AAA52125.1| 209|Homo sapiens CTSB protein. 74 6e-13
L16510-1|AAC37547.1| 339|Homo sapiens cathepsin B protein. 74 6e-13
BC095408-1|AAH95408.1| 339|Homo sapiens cathepsin B protein. 74 6e-13
BC010240-1|AAH10240.1| 339|Homo sapiens cathepsin B protein. 74 6e-13
BC025419-1|AAH25419.1| 297|Homo sapiens CTSZ protein protein. 70 1e-11
BC070278-1|AAH70278.1| 476|Homo sapiens tubulointerstitial neph... 61 5e-09
BC064633-1|AAH64633.1| 467|Homo sapiens tubulointerstitial neph... 61 5e-09
AY358421-1|AAQ88787.1| 467|Homo sapiens LCN7 protein. 61 5e-09
AL589946-2|CAH70302.1| 476|Homo sapiens tubulointerstitial neph... 61 5e-09
AL359380-5|CAI16272.1| 476|Homo sapiens tubulointerstitial neph... 61 5e-09
AK075398-1|BAC11596.1| 467|Homo sapiens protein ( Homo sapiens ... 61 5e-09
AF236155-1|AAG40154.1| 467|Homo sapiens tubulointerstitial neph... 61 5e-09
AF236150-1|AAG38876.1| 467|Homo sapiens tubulointerstitial neph... 61 5e-09
AF205436-1|AAG33699.1| 467|Homo sapiens oxidized-LDL responsive... 61 5e-09
AB050719-1|BAB18727.1| 467|Homo sapiens glucocorticoid-inducibl... 61 5e-09
AB050716-1|BAB18636.1| 467|Homo sapiens glucocorticoid-inducibl... 61 5e-09
AB022277-1|BAA84949.1| 476|Homo sapiens tubulointerstitial neph... 61 5e-09
AF195116-1|AAF08931.1| 476|Homo sapiens tubulointerstitial neph... 60 1e-08
X05256-1|CAA28877.1| 42|Homo sapiens protein ( Human mRNA frag... 54 7e-07
BC009048-1|AAH09048.1| 218|Homo sapiens TINAGL1 protein protein. 51 5e-06
AK027839-1|BAB55403.1| 218|Homo sapiens protein ( Homo sapiens ... 50 2e-05
Y18460-1|CAA77178.1| 195|Homo sapiens cathepsin B protein. 45 4e-04
AL589946-1|CAH70301.1| 155|Homo sapiens tubulointerstitial neph... 45 4e-04
AF195117-1|AAF08932.1| 333|Homo sapiens tubulointerstitial neph... 45 4e-04
AK074124-1|BAB84950.1| 284|Homo sapiens FLJ00196 protein protein. 33 1.1
BC089428-1|AAH89428.1| 1192|Homo sapiens PLEKHG1 protein protein. 31 7.5
AL450339-2|CAI12939.1| 1385|Homo sapiens pleckstrin homology dom... 31 7.5
AL035086-3|CAI42790.1| 1385|Homo sapiens pleckstrin homology dom... 31 7.5
AB033035-1|BAA86523.1| 1113|Homo sapiens KIAA1209 protein protein. 31 7.5
>BC036451-1|AAH36451.1| 484|Homo sapiens cathepsin F protein.
Length = 484
Score = 213 bits (521), Expect = 6e-55
Identities = 110/293 (37%), Positives = 169/293 (57%), Gaps = 6/293 (2%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLP 726
N+ Y S+ E R +F +N+ + I +A+Y + KFSDL+++E Y L
Sbjct: 195 NRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLR 254
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKH 546
+ N K+ P E+DWR VT VK+QGMCG+CWAF+ G++E Q+ +
Sbjct: 255 KEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 312
Query: 545 NELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY Y+ +C ++ K
Sbjct: 313 GTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEK 372
Query: 365 FLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSGLNH 198
V + D + E+KL L GPI +AI+A + Y+ GI + C ++H
Sbjct: 373 AKVYINDSVE-LSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDH 431
Query: 197 AVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 39
AVLLVGYG +++P+W KN+WGTDWGE G++ + + ACG+ N +AS+AV+
Sbjct: 432 AVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGV-NTMASSAVV 483
>BC011682-1|AAH11682.1| 484|Homo sapiens cathepsin F protein.
Length = 484
Score = 213 bits (521), Expect = 6e-55
Identities = 110/293 (37%), Positives = 169/293 (57%), Gaps = 6/293 (2%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLP 726
N+ Y S+ E R +F +N+ + I +A+Y + KFSDL+++E Y L
Sbjct: 195 NRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLR 254
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKH 546
+ N K+ P E+DWR VT VK+QGMCG+CWAF+ G++E Q+ +
Sbjct: 255 KEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 312
Query: 545 NELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY Y+ +C ++ K
Sbjct: 313 GTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEK 372
Query: 365 FLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSGLNH 198
V + D + E+KL L GPI +AI+A + Y+ GI + C ++H
Sbjct: 373 AKVYINDSVE-LSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDH 431
Query: 197 AVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 39
AVLLVGYG +++P+W KN+WGTDWGE G++ + + ACG+ N +AS+AV+
Sbjct: 432 AVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGV-NTMASSAVV 483
>AJ007331-1|CAB42883.1| 484|Homo sapiens cysteine proteinase protein.
Length = 484
Score = 213 bits (521), Expect = 6e-55
Identities = 110/293 (37%), Positives = 169/293 (57%), Gaps = 6/293 (2%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLP 726
N+ Y S+ E R +F +N+ + I +A+Y + KFSDL+++E Y L
Sbjct: 195 NRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLR 254
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKH 546
+ N K+ P E+DWR VT VK+QGMCG+CWAF+ G++E Q+ +
Sbjct: 255 KEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 312
Query: 545 NELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY Y+ +C ++ K
Sbjct: 313 GTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEK 372
Query: 365 FLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSGLNH 198
V + D + E+KL L GPI +AI+A + Y+ GI + C ++H
Sbjct: 373 AKVYINDSVE-LSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDH 431
Query: 197 AVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 39
AVLLVGYG +++P+W KN+WGTDWGE G++ + + ACG+ N +AS+AV+
Sbjct: 432 AVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGV-NTMASSAVV 483
>AF132894-1|AAD41790.1| 484|Homo sapiens cathepsin F protein.
Length = 484
Score = 213 bits (521), Expect = 6e-55
Identities = 110/293 (37%), Positives = 169/293 (57%), Gaps = 6/293 (2%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLP 726
N+ Y S+ E R +F +N+ + I +A+Y + KFSDL+++E Y L
Sbjct: 195 NRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLR 254
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKH 546
+ N K+ P E+DWR VT VK+QGMCG+CWAF+ G++E Q+ +
Sbjct: 255 KEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 312
Query: 545 NELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY Y+ +C ++ K
Sbjct: 313 GTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEK 372
Query: 365 FLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSGLNH 198
V + D + E+KL L GPI +AI+A + Y+ GI + C ++H
Sbjct: 373 AKVYINDSVE-LSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDH 431
Query: 197 AVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 39
AVLLVGYG +++P+W KN+WGTDWGE G++ + + ACG+ N +AS+AV+
Sbjct: 432 AVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGV-NTMASSAVV 483
>AF088886-1|AAD26616.2| 484|Homo sapiens cathepsin F precursor
protein.
Length = 484
Score = 213 bits (521), Expect = 6e-55
Identities = 110/293 (37%), Positives = 169/293 (57%), Gaps = 6/293 (2%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLP 726
N+ Y S+ E R +F +N+ + I +A+Y + KFSDL+++E Y L
Sbjct: 195 NRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLR 254
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKH 546
+ N K+ P E+DWR VT VK+QGMCG+CWAF+ G++E Q+ +
Sbjct: 255 KEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 312
Query: 545 NELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY Y+ +C ++ K
Sbjct: 313 GTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEK 372
Query: 365 FLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSGLNH 198
V + D + E+KL L GPI +AI+A + Y+ GI + C ++H
Sbjct: 373 AKVYINDSVE-LSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDH 431
Query: 197 AVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 39
AVLLVGYG +++P+W KN+WGTDWGE G++ + + ACG+ N +AS+AV+
Sbjct: 432 AVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGV-NTMASSAVV 483
>AF071749-1|AAC78839.1| 302|Homo sapiens cathepsin F protein.
Length = 302
Score = 213 bits (521), Expect = 6e-55
Identities = 110/293 (37%), Positives = 169/293 (57%), Gaps = 6/293 (2%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLP 726
N+ Y S+ E R +F +N+ + I +A+Y + KFSDL+++E Y L
Sbjct: 13 NRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLR 72
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKH 546
+ N K+ P E+DWR VT VK+QGMCG+CWAF+ G++E Q+ +
Sbjct: 73 KEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 130
Query: 545 NELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY Y+ +C ++ K
Sbjct: 131 GTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEK 190
Query: 365 FLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSGLNH 198
V + D + E+KL L GPI +AI+A + Y+ GI + C ++H
Sbjct: 191 AKVYINDSVE-LSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDH 249
Query: 197 AVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 39
AVLLVGYG +++P+W KN+WGTDWGE G++ + + ACG+ N +AS+AV+
Sbjct: 250 AVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGV-NTMASSAVV 301
>AF071748-1|AAC78838.1| 338|Homo sapiens cathepsin F protein.
Length = 338
Score = 213 bits (521), Expect = 6e-55
Identities = 110/293 (37%), Positives = 169/293 (57%), Gaps = 6/293 (2%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLP 726
N+ Y S+ E R +F +N+ + I +A+Y + KFSDL+++E Y L
Sbjct: 49 NRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLR 108
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKH 546
+ N K+ P E+DWR VT VK+QGMCG+CWAF+ G++E Q+ +
Sbjct: 109 KEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 166
Query: 545 NELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY Y+ +C ++ K
Sbjct: 167 GTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEK 226
Query: 365 FLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSGLNH 198
V + D + E+KL L GPI +AI+A + Y+ GI + C ++H
Sbjct: 227 AKVYINDSVE-LSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDH 285
Query: 197 AVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 39
AVLLVGYG +++P+W KN+WGTDWGE G++ + + ACG+ N +AS+AV+
Sbjct: 286 AVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGV-NTMASSAVV 337
>AF136279-1|AAF13146.1| 484|Homo sapiens cathepsin F precursor
protein.
Length = 484
Score = 212 bits (517), Expect = 2e-54
Identities = 109/293 (37%), Positives = 169/293 (57%), Gaps = 6/293 (2%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLP 726
N+ Y S+ E R +F +N+ + I +A+Y + KFSDL+++E Y L
Sbjct: 195 NRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLR 254
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKH 546
+ N K+ P E+DWR VT VK+QGMCG+CWAF+ G+++ Q+ +
Sbjct: 255 KEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVKGQWFLNQ 312
Query: 545 NELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY Y+ +C ++ K
Sbjct: 313 GTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEK 372
Query: 365 FLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSGLNH 198
V + D + E+KL L GPI +AI+A + Y+ GI + C ++H
Sbjct: 373 AKVYINDSVE-LSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDH 431
Query: 197 AVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 39
AVLLVGYG +++P+W KN+WGTDWGE G++ + + ACG+ N +AS+AV+
Sbjct: 432 AVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGV-NTMASSAVV 483
>CR541680-1|CAG46481.1| 338|Homo sapiens CTSF protein.
Length = 338
Score = 210 bits (514), Expect = 4e-54
Identities = 109/293 (37%), Positives = 168/293 (57%), Gaps = 6/293 (2%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLP 726
N+ Y S+ E R +F +N+ + I +A+Y + KFSDL+++E Y L
Sbjct: 49 NRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLR 108
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKH 546
+ N K+ P E+DWR VT VK+QGMCG+CWAF+ G++E Q+ +
Sbjct: 109 KEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 166
Query: 545 NELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
L++LSEQ+++DCD +D C GGL A+ AI +GG++ DY Y+ +C ++ K
Sbjct: 167 GTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETVDDYSYQGHMQSCNFSAEK 226
Query: 365 FLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSGLNH 198
V + D + E+KL L GPI +AI+A + Y+ GI + C ++H
Sbjct: 227 AKVYINDSVE-LSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDH 285
Query: 197 AVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAVI 39
AVLLVGYG +++P+W KN+WGTDWGE G++ + + ACG+ N +AS+AV+
Sbjct: 286 AVLLVGYGNRSDVPFWAIKNSWGTDWGEKGYYYLHRGSGACGV-NTMASSAVV 337
>X16832-1|CAA34734.1| 335|Homo sapiens protein ( Human mRNA for
cathepsin H (EC 3.4.22.16). ).
Length = 335
Score = 195 bits (476), Expect = 2e-49
Identities = 112/287 (39%), Positives = 159/287 (55%), Gaps = 11/287 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQ 720
K YS+E E R + F N +I + N N + K +N+FSD+S E KY L ++
Sbjct: 44 KTYSTE-EYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKY----LWSE 98
Query: 719 TQNFCKVILLDQPPGKGPL--EFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIK 549
QN C + G GP DWR+ N V+ VKNQG CG+CW F+T G+LES AI
Sbjct: 99 PQN-CSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIA 157
Query: 548 HNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMN 375
++++L+EQQ++DC DF + GC GGL AFE I+ G+ E YPY+ + C+
Sbjct: 158 TGKMLSLAEQQLVDCAQDFNNYGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQ 217
Query: 374 SNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG- 207
K + VKD I EE + + + L P+ A + D + Y+ GI C +
Sbjct: 218 PGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPD 277
Query: 206 -LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGM 69
+NHAVL VGYG +N IPYW KN+WG WG +G+F +++ N CG+
Sbjct: 278 KVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGL 324
>CR456881-1|CAG33162.1| 335|Homo sapiens CTSH protein.
Length = 335
Score = 195 bits (476), Expect = 2e-49
Identities = 112/287 (39%), Positives = 159/287 (55%), Gaps = 11/287 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQ 720
K YS+E E R + F N +I + N N + K +N+FSD+S E KY L ++
Sbjct: 44 KTYSTE-EYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKY----LWSE 98
Query: 719 TQNFCKVILLDQPPGKGPL--EFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIK 549
QN C + G GP DWR+ N V+ VKNQG CG+CW F+T G+LES AI
Sbjct: 99 PQN-CSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIA 157
Query: 548 HNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMN 375
++++L+EQQ++DC DF + GC GGL AFE I+ G+ E YPY+ + C+
Sbjct: 158 TGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQ 217
Query: 374 SNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG- 207
K + VKD I EE + + + L P+ A + D + Y+ GI C +
Sbjct: 218 PGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPD 277
Query: 206 -LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGM 69
+NHAVL VGYG +N IPYW KN+WG WG +G+F +++ N CG+
Sbjct: 278 KVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGL 324
>BC002479-1|AAH02479.1| 335|Homo sapiens cathepsin H protein.
Length = 335
Score = 195 bits (476), Expect = 2e-49
Identities = 112/287 (39%), Positives = 159/287 (55%), Gaps = 11/287 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQ 720
K YS+E E R + F N +I + N N + K +N+FSD+S E KY L ++
Sbjct: 44 KTYSTE-EYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKY----LWSE 98
Query: 719 TQNFCKVILLDQPPGKGPL--EFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIK 549
QN C + G GP DWR+ N V+ VKNQG CG+CW F+T G+LES AI
Sbjct: 99 PQN-CSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIA 157
Query: 548 HNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMN 375
++++L+EQQ++DC DF + GC GGL AFE I+ G+ E YPY+ + C+
Sbjct: 158 TGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQ 217
Query: 374 SNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG- 207
K + VKD I EE + + + L P+ A + D + Y+ GI C +
Sbjct: 218 PGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPD 277
Query: 206 -LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGM 69
+NHAVL VGYG +N IPYW KN+WG WG +G+F +++ N CG+
Sbjct: 278 KVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGL 324
>AF426248-1|AAL23962.1| 323|Homo sapiens truncated cathepsin H
protein.
Length = 323
Score = 195 bits (476), Expect = 2e-49
Identities = 112/287 (39%), Positives = 159/287 (55%), Gaps = 11/287 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQ 720
K YS+E E R + F N +I + N N + K +N+FSD+S E KY L ++
Sbjct: 32 KTYSTE-EYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKY----LWSE 86
Query: 719 TQNFCKVILLDQPPGKGPL--EFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIK 549
QN C + G GP DWR+ N V+ VKNQG CG+CW F+T G+LES AI
Sbjct: 87 PQN-CSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIA 145
Query: 548 HNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMN 375
++++L+EQQ++DC DF + GC GGL AFE I+ G+ E YPY+ + C+
Sbjct: 146 TGKMLSLAEQQLVDCAQDFNNYGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQ 205
Query: 374 SNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG- 207
K + VKD I EE + + + L P+ A + D + Y+ GI C +
Sbjct: 206 PGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPD 265
Query: 206 -LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGM 69
+NHAVL VGYG +N IPYW KN+WG WG +G+F +++ N CG+
Sbjct: 266 KVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGL 312
>AF426247-1|AAL23961.1| 335|Homo sapiens cathepsin H protein.
Length = 335
Score = 195 bits (476), Expect = 2e-49
Identities = 112/287 (39%), Positives = 159/287 (55%), Gaps = 11/287 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQ 720
K YS+E E R + F N +I + N N + K +N+FSD+S E KY L ++
Sbjct: 44 KTYSTE-EYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKY----LWSE 98
Query: 719 TQNFCKVILLDQPPGKGPL--EFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIK 549
QN C + G GP DWR+ N V+ VKNQG CG+CW F+T G+LES AI
Sbjct: 99 PQN-CSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIA 157
Query: 548 HNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMN 375
++++L+EQQ++DC DF + GC GGL AFE I+ G+ E YPY+ + C+
Sbjct: 158 TGKMLSLAEQQLVDCAQDFNNYGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQ 217
Query: 374 SNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG- 207
K + VKD I EE + + + L P+ A + D + Y+ GI C +
Sbjct: 218 PGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPD 277
Query: 206 -LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNINACGM 69
+NHAVL VGYG +N IPYW KN+WG WG +G+F +++ N CG+
Sbjct: 278 KVNHAVLAVGYGEKNGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGL 324
>X82153-1|CAA57649.1| 329|Homo sapiens Cathepsin O protein.
Length = 329
Score = 192 bits (469), Expect = 1e-48
Identities = 107/293 (36%), Positives = 160/293 (54%), Gaps = 11/293 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y+++V+++ R I++ NL I N S YE+ N D++ +E + K TGL
Sbjct: 35 KQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLK 94
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P + + + G+ P D+R+ VT VKNQG CG+CWAF+++G+LE Q
Sbjct: 95 VPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 154
Query: 551 KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 372
K +L+NLS Q ++DC + GC GG + AF+ + K G+ E YPY +C N
Sbjct: 155 KTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP 214
Query: 371 NKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSG 207
+ + YR I EK LK + VGP+ +AIDA+ Y +G+ + C
Sbjct: 215 TGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDN 273
Query: 206 LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN-INACGMRNELAS 51
LNHAVL VGYG++ +W KN+WG +WG G+ + +N NACG+ N LAS
Sbjct: 274 LNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIAN-LAS 325
>U13665-1|AAA65233.1| 329|Homo sapiens cathepsin O protein.
Length = 329
Score = 192 bits (469), Expect = 1e-48
Identities = 107/293 (36%), Positives = 160/293 (54%), Gaps = 11/293 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y+++V+++ R I++ NL I N S YE+ N D++ +E + K TGL
Sbjct: 35 KQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLK 94
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P + + + G+ P D+R+ VT VKNQG CG+CWAF+++G+LE Q
Sbjct: 95 VPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 154
Query: 551 KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 372
K +L+NLS Q ++DC + GC GG + AF+ + K G+ E YPY +C N
Sbjct: 155 KTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP 214
Query: 371 NKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSG 207
+ + YR I EK LK + VGP+ +AIDA+ Y +G+ + C
Sbjct: 215 TGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDN 273
Query: 206 LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN-INACGMRNELAS 51
LNHAVL VGYG++ +W KN+WG +WG G+ + +N NACG+ N LAS
Sbjct: 274 LNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIAN-LAS 325
>S79895-1|AAB35521.1| 329|Homo sapiens cathepsin O2 protein.
Length = 329
Score = 192 bits (469), Expect = 1e-48
Identities = 107/293 (36%), Positives = 160/293 (54%), Gaps = 11/293 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y+++V+++ R I++ NL I N S YE+ N D++ +E + K TGL
Sbjct: 35 KQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLK 94
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P + + + G+ P D+R+ VT VKNQG CG+CWAF+++G+LE Q
Sbjct: 95 VPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 154
Query: 551 KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 372
K +L+NLS Q ++DC + GC GG + AF+ + K G+ E YPY +C N
Sbjct: 155 KTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP 214
Query: 371 NKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSG 207
+ + YR I EK LK + VGP+ +AIDA+ Y +G+ + C
Sbjct: 215 TGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDN 273
Query: 206 LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN-INACGMRNELAS 51
LNHAVL VGYG++ +W KN+WG +WG G+ + +N NACG+ N LAS
Sbjct: 274 LNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIAN-LAS 325
>CR541719-1|CAG46520.1| 329|Homo sapiens CTSK protein.
Length = 329
Score = 192 bits (469), Expect = 1e-48
Identities = 107/293 (36%), Positives = 160/293 (54%), Gaps = 11/293 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y+++V+++ R I++ NL I N S YE+ N D++ +E + K TGL
Sbjct: 35 KQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLK 94
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P + + + G+ P D+R+ VT VKNQG CG+CWAF+++G+LE Q
Sbjct: 95 VPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 154
Query: 551 KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 372
K +L+NLS Q ++DC + GC GG + AF+ + K G+ E YPY +C N
Sbjct: 155 KTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP 214
Query: 371 NKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSG 207
+ + YR I EK LK + VGP+ +AIDA+ Y +G+ + C
Sbjct: 215 TGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDN 273
Query: 206 LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN-INACGMRNELAS 51
LNHAVL VGYG++ +W KN+WG +WG G+ + +N NACG+ N LAS
Sbjct: 274 LNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIAN-LAS 325
>CR541675-1|CAG46476.1| 329|Homo sapiens CTSK protein.
Length = 329
Score = 192 bits (469), Expect = 1e-48
Identities = 107/293 (36%), Positives = 160/293 (54%), Gaps = 11/293 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y+++V+++ R I++ NL I N S YE+ N D++ +E + K TGL
Sbjct: 35 KQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLK 94
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P + + + G+ P D+R+ VT VKNQG CG+CWAF+++G+LE Q
Sbjct: 95 VPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 154
Query: 551 KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 372
K +L+NLS Q ++DC + GC GG + AF+ + K G+ E YPY +C N
Sbjct: 155 KTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP 214
Query: 371 NKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSG 207
+ + YR I EK LK + VGP+ +AIDA+ Y +G+ + C
Sbjct: 215 TGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDN 273
Query: 206 LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN-INACGMRNELAS 51
LNHAVL VGYG++ +W KN+WG +WG G+ + +N NACG+ N LAS
Sbjct: 274 LNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIAN-LAS 325
>BC016058-1|AAH16058.1| 329|Homo sapiens cathepsin K protein.
Length = 329
Score = 192 bits (469), Expect = 1e-48
Identities = 107/293 (36%), Positives = 160/293 (54%), Gaps = 11/293 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y+++V+++ R I++ NL I N S YE+ N D++ +E + K TGL
Sbjct: 35 KQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLK 94
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P + + + G+ P D+R+ VT VKNQG CG+CWAF+++G+LE Q
Sbjct: 95 VPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 154
Query: 551 KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 372
K +L+NLS Q ++DC + GC GG + AF+ + K G+ E YPY +C N
Sbjct: 155 KTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP 214
Query: 371 NKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSG 207
+ + YR I EK LK + VGP+ +AIDA+ Y +G+ + C
Sbjct: 215 TGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDN 273
Query: 206 LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN-INACGMRNELAS 51
LNHAVL VGYG++ +W KN+WG +WG G+ + +N NACG+ N LAS
Sbjct: 274 LNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIAN-LAS 325
>AL356292-1|CAI13649.1| 329|Homo sapiens cathepsin K protein.
Length = 329
Score = 192 bits (469), Expect = 1e-48
Identities = 107/293 (36%), Positives = 160/293 (54%), Gaps = 11/293 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y+++V+++ R I++ NL I N S YE+ N D++ +E + K TGL
Sbjct: 35 KQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLK 94
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P + + + G+ P D+R+ VT VKNQG CG+CWAF+++G+LE Q
Sbjct: 95 VPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 154
Query: 551 KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 372
K +L+NLS Q ++DC + GC GG + AF+ + K G+ E YPY +C N
Sbjct: 155 KTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP 214
Query: 371 NKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSG 207
+ + YR I EK LK + VGP+ +AIDA+ Y +G+ + C
Sbjct: 215 TGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDN 273
Query: 206 LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN-INACGMRNELAS 51
LNHAVL VGYG++ +W KN+WG +WG G+ + +N NACG+ N LAS
Sbjct: 274 LNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIAN-LAS 325
>AL355860-1|CAI12795.1| 329|Homo sapiens cathepsin K protein.
Length = 329
Score = 192 bits (469), Expect = 1e-48
Identities = 107/293 (36%), Positives = 160/293 (54%), Gaps = 11/293 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y+++V+++ R I++ NL I N S YE+ N D++ +E + K TGL
Sbjct: 35 KQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLK 94
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P + + + G+ P D+R+ VT VKNQG CG+CWAF+++G+LE Q
Sbjct: 95 VPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 154
Query: 551 KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 372
K +L+NLS Q ++DC + GC GG + AF+ + K G+ E YPY +C N
Sbjct: 155 KTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP 214
Query: 371 NKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSG 207
+ + YR I EK LK + VGP+ +AIDA+ Y +G+ + C
Sbjct: 215 TGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDN 273
Query: 206 LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN-INACGMRNELAS 51
LNHAVL VGYG++ +W KN+WG +WG G+ + +N NACG+ N LAS
Sbjct: 274 LNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIAN-LAS 325
>U20280-1|AAA95998.1| 329|Homo sapiens cathepsin X protein.
Length = 329
Score = 190 bits (462), Expect = 8e-48
Identities = 106/293 (36%), Positives = 159/293 (54%), Gaps = 11/293 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y+++V+++ I++ NL I N S YE+ N D++ +E + K TGL
Sbjct: 35 KQYNNKVDEISPRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLK 94
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P + + + G+ P D+R+ VT VKNQG CG+CWAF+++G+LE Q
Sbjct: 95 VPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 154
Query: 551 KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 372
K +L+NLS Q ++DC + GC GG + AF+ + K G+ E YPY +C N
Sbjct: 155 KTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNP 214
Query: 371 NKFLVQVKDCYRYIIVYEEK-LKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCFDSG 207
+ + YR I EK LK + VGP+ +AIDA+ Y +G+ + C
Sbjct: 215 TGKAAKCRG-YREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDN 273
Query: 206 LNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQN-INACGMRNELAS 51
LNHAVL VGYG++ +W KN+WG +WG G+ + +N NACG+ N LAS
Sbjct: 274 LNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIAN-LAS 325
>X77383-1|CAA54562.1| 321|Homo sapiens cathepsin O protein.
Length = 321
Score = 182 bits (443), Expect = 2e-45
Identities = 102/280 (36%), Positives = 153/280 (54%), Gaps = 6/280 (2%)
Frame = -3
Query: 863 RFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQ 684
R + +H + ++N +A Y IN+FS L +E A Y S P++ + + +
Sbjct: 45 RESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLR-SKPSKFPRYSAEVHMSI 103
Query: 683 PPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC 504
P PL FDWR VT V+NQ MCG CWAF+ +G++ES +AIK L +LS QQ+IDC
Sbjct: 104 PNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDC 163
Query: 503 DFVDAGCNGGLLHTAFEAIIKMGGVQL--ESDYPYEADNNNCRMNSNK---FLVQVKDCY 339
+ + GCNGG A + KM V+L +S+YP++A N C S F ++ Y
Sbjct: 164 SYNNYGCNGGSTLNALNWLNKM-QVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKGYSAY 222
Query: 338 RYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK-YCFDSGLNHAVLLVGYGVENN 162
+ +E K LL GP+ + +DA +Y GII+ +C NHAVL+ G+ +
Sbjct: 223 DFSDQEDEMAKALLTF-GPLVVIVDAVSWQDYLGGIIQHHCSSGEANHAVLITGFDKTGS 281
Query: 161 IPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAV 42
PYW +N+WG+ WG DG+ V+ N CG+ + ++S V
Sbjct: 282 TPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVSSIFV 321
>BC049206-1|AAH49206.1| 321|Homo sapiens cathepsin O protein.
Length = 321
Score = 182 bits (443), Expect = 2e-45
Identities = 102/280 (36%), Positives = 153/280 (54%), Gaps = 6/280 (2%)
Frame = -3
Query: 863 RFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQ 684
R + +H + ++N +A Y IN+FS L +E A Y S P++ + + +
Sbjct: 45 RESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLR-SKPSKFPRYSAEVHMSI 103
Query: 683 PPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC 504
P PL FDWR VT V+NQ MCG CWAF+ +G++ES +AIK L +LS QQ+IDC
Sbjct: 104 PNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDC 163
Query: 503 DFVDAGCNGGLLHTAFEAIIKMGGVQL--ESDYPYEADNNNCRMNSNK---FLVQVKDCY 339
+ + GCNGG A + KM V+L +S+YP++A N C S F ++ Y
Sbjct: 164 SYNNYGCNGGSTLNALNWLNKM-QVKLVKDSEYPFKAQNGLCHYFSGSHSGFSIKGYSAY 222
Query: 338 RYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK-YCFDSGLNHAVLLVGYGVENN 162
+ +E K LL GP+ + +DA +Y GII+ +C NHAVL+ G+ +
Sbjct: 223 DFSDQEDEMAKALLTF-GPLVVIVDAVSWQDYLGGIIQHHCSSGEANHAVLITGFDKTGS 281
Query: 161 IPYWTFKNTWGTDWGEDGFFRVQQNINACGMRNELASTAV 42
PYW +N+WG+ WG DG+ V+ N CG+ + ++S V
Sbjct: 282 TPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVSSIFV 321
>X07549-1|CAA30428.1| 248|Homo sapiens cathepsin H protein.
Length = 248
Score = 176 bits (428), Expect = 1e-43
Identities = 87/211 (41%), Positives = 123/211 (58%), Gaps = 8/211 (3%)
Frame = -3
Query: 677 GKGPLEFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC- 504
G P DWR+ N V+ VKNQG CG+CW F+T G+LES AI ++++L+EQQ++DC
Sbjct: 27 GPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCA 86
Query: 503 -DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYII 327
DF + GC GGL AFE I+ G+ E YPY+ + C+ K + VKD I
Sbjct: 87 QDFNNYGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITI 146
Query: 326 VYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKY--CFDSG--LNHAVLLVGYGVENN 162
EE + + + L P+ A + D + Y+ GI C + +NHAVL VGYG +N
Sbjct: 147 YDEEAMVEAVALYNPVSFAFEVTQDFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEKNG 206
Query: 161 IPYWTFKNTWGTDWGEDGFFRVQQNINACGM 69
IPYW KN+WG WG +G+F +++ N CG+
Sbjct: 207 IPYWIVKNSWGPQWGMNGYFLIERGKNMCGL 237
>CR541676-1|CAG46477.1| 331|Homo sapiens CTSS protein.
Length = 331
Score = 170 bits (414), Expect = 5e-42
Identities = 98/291 (33%), Positives = 158/291 (54%), Gaps = 15/291 (5%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y + E+ R I++ NL ++ N S Y++ N D++ +E ++ + L
Sbjct: 37 KQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLR 96
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P+Q Q + P P DWR VT VK QG CGACWAF+ +G+LE+Q +
Sbjct: 97 VPSQWQR--NITYKSNPNWILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKL 154
Query: 551 KHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 381
K +L++LS Q ++DC + + GCNGG + TAF+ II G+ ++ YPY+A + C+
Sbjct: 155 KTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQ 214
Query: 380 MNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMAIDA--ADIVNYKQGI-IKYC 219
+S + C +Y + Y E+ LK+ + GP+ + +DA Y+ G+ +
Sbjct: 215 YDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPS 271
Query: 218 FDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNI-NACGM 69
+NH VL+VGYG N YW KN+WG ++GE+G+ R+ +N N CG+
Sbjct: 272 CTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGI 322
>BC002642-1|AAH02642.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 170 bits (414), Expect = 5e-42
Identities = 98/291 (33%), Positives = 158/291 (54%), Gaps = 15/291 (5%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y + E+ R I++ NL ++ N S Y++ N D++ +E ++ + L
Sbjct: 37 KQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLR 96
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P+Q Q + P P DWR VT VK QG CGACWAF+ +G+LE+Q +
Sbjct: 97 VPSQWQR--NITYKSNPNWILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKL 154
Query: 551 KHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 381
K +L++LS Q ++DC + + GCNGG + TAF+ II G+ ++ YPY+A + C+
Sbjct: 155 KTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQ 214
Query: 380 MNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMAIDA--ADIVNYKQGI-IKYC 219
+S + C +Y + Y E+ LK+ + GP+ + +DA Y+ G+ +
Sbjct: 215 YDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPS 271
Query: 218 FDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNI-NACGM 69
+NH VL+VGYG N YW KN+WG ++GE+G+ R+ +N N CG+
Sbjct: 272 CTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGI 322
>AL356292-9|CAI13657.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 170 bits (414), Expect = 5e-42
Identities = 98/291 (33%), Positives = 158/291 (54%), Gaps = 15/291 (5%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y + E+ R I++ NL ++ N S Y++ N D++ +E ++ + L
Sbjct: 37 KQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLR 96
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P+Q Q + P P DWR VT VK QG CGACWAF+ +G+LE+Q +
Sbjct: 97 VPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKL 154
Query: 551 KHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 381
K +L++LS Q ++DC + + GCNGG + TAF+ II G+ ++ YPY+A + C+
Sbjct: 155 KTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQ 214
Query: 380 MNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMAIDA--ADIVNYKQGI-IKYC 219
+S + C +Y + Y E+ LK+ + GP+ + +DA Y+ G+ +
Sbjct: 215 YDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPS 271
Query: 218 FDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNI-NACGM 69
+NH VL+VGYG N YW KN+WG ++GE+G+ R+ +N N CG+
Sbjct: 272 CTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGI 322
>S93414-1|AAB22005.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 169 bits (412), Expect = 9e-42
Identities = 98/291 (33%), Positives = 157/291 (53%), Gaps = 15/291 (5%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y + E+ R I++ NL ++ N S Y++ N D++ +E ++ + L
Sbjct: 37 KQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLTSSLR 96
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P+Q Q + P P DWR VT VK QG CGACWAF+ +G+LE+Q +
Sbjct: 97 VPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKL 154
Query: 551 KHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 381
K +L+ LS Q ++DC + + GCNGG + TAF+ II G+ ++ YPY+A + C+
Sbjct: 155 KTGKLVTLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQ 214
Query: 380 MNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMAIDA--ADIVNYKQGI-IKYC 219
+S + C +Y + Y E+ LK+ + GP+ + +DA Y+ G+ +
Sbjct: 215 YDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPS 271
Query: 218 FDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNI-NACGM 69
+NH VL+VGYG N YW KN+WG ++GE+G+ R+ +N N CG+
Sbjct: 272 CTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGI 322
>M86553-1|AAA35655.1| 331|Homo sapiens cathepsin protein.
Length = 331
Score = 169 bits (412), Expect = 9e-42
Identities = 98/291 (33%), Positives = 157/291 (53%), Gaps = 15/291 (5%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y + E+ R I++ NL ++ N S Y++ N D++ +E ++ + L
Sbjct: 37 KQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLTSSLR 96
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P+Q Q + P P DWR VT VK QG CGACWAF+ +G+LE+Q +
Sbjct: 97 VPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKL 154
Query: 551 KHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 381
K +L+ LS Q ++DC + + GCNGG + TAF+ II G+ ++ YPY+A + C+
Sbjct: 155 KTGKLVTLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQ 214
Query: 380 MNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMAIDA--ADIVNYKQGI-IKYC 219
+S + C +Y + Y E+ LK+ + GP+ + +DA Y+ G+ +
Sbjct: 215 YDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPS 271
Query: 218 FDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNI-NACGM 69
+NH VL+VGYG N YW KN+WG ++GE+G+ R+ +N N CG+
Sbjct: 272 CTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGI 322
>M90696-1|AAC37592.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 169 bits (411), Expect = 1e-41
Identities = 98/291 (33%), Positives = 158/291 (54%), Gaps = 15/291 (5%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y + E+ R I++ NL ++ N S Y++ N D++ +E ++ + L
Sbjct: 37 KQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLR 96
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P+Q Q + P P DWR VT VK QG CGACWAF+ +G+LE+Q +
Sbjct: 97 VPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKL 154
Query: 551 KHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 381
K +L++LS Q ++DC + + GCNGG + TAF+ II G+ ++ YPY+A + C+
Sbjct: 155 KTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDLKCQ 214
Query: 380 MNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMAIDA--ADIVNYKQGI-IKYC 219
+S + C +Y + Y E+ LK+ + GP+ + +DA Y+ G+ +
Sbjct: 215 YDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPS 271
Query: 218 FDSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRVQQNI-NACGM 69
+NH VL+VGYG N YW KN+WG ++GE+G+ R+ +N N CG+
Sbjct: 272 CTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGI 322
>X12451-1|CAA30981.1| 333|Homo sapiens pro-(cathepsin L) protein.
Length = 333
Score = 163 bits (397), Expect = 6e-40
Identities = 105/294 (35%), Positives = 149/294 (50%), Gaps = 17/294 (5%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 735
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 734 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 558
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 557 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 384
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 383 RMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCF 216
+ N K+ V + I E+ L + VGPI +AIDA + YK+GI C
Sbjct: 212 KYNP-KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCS 270
Query: 215 DSGLNHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
++H VL+VGYG E +N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 271 SEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>M20496-1|AAA66974.1| 333|Homo sapiens CTSL protein.
Length = 333
Score = 163 bits (397), Expect = 6e-40
Identities = 105/294 (35%), Positives = 149/294 (50%), Gaps = 17/294 (5%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 735
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 734 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 558
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 557 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 384
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 383 RMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCF 216
+ N K+ V + I E+ L + VGPI +AIDA + YK+GI C
Sbjct: 212 KYNP-KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCS 270
Query: 215 DSGLNHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
++H VL+VGYG E +N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 271 SEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>CR457053-1|CAG33334.1| 333|Homo sapiens CTSL protein.
Length = 333
Score = 163 bits (397), Expect = 6e-40
Identities = 105/294 (35%), Positives = 149/294 (50%), Gaps = 17/294 (5%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 735
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 734 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 558
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 557 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 384
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 383 RMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCF 216
+ N K+ V + I E+ L + VGPI +AIDA + YK+GI C
Sbjct: 212 KYNP-KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCS 270
Query: 215 DSGLNHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
++H VL+VGYG E +N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 271 SEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>AL160279-3|CAI16308.1| 333|Homo sapiens cathepsin L1 protein.
Length = 333
Score = 163 bits (397), Expect = 6e-40
Identities = 105/294 (35%), Positives = 149/294 (50%), Gaps = 17/294 (5%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 735
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 734 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 558
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 557 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 384
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 383 RMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCF 216
+ N K+ V + I E+ L + VGPI +AIDA + YK+GI C
Sbjct: 212 KYNP-KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCS 270
Query: 215 DSGLNHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
++H VL+VGYG E +N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 271 SEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>BC012612-1|AAH12612.1| 333|Homo sapiens cathepsin L1 protein.
Length = 333
Score = 163 bits (396), Expect = 8e-40
Identities = 105/294 (35%), Positives = 149/294 (50%), Gaps = 17/294 (5%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 735
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNVKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 734 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 558
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 557 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 384
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 383 RMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCF 216
+ N K+ V + I E+ L + VGPI +AIDA + YK+GI C
Sbjct: 212 KYNP-KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCS 270
Query: 215 DSGLNHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
++H VL+VGYG E +N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 271 SEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>BC142983-1|AAI42984.1| 333|Homo sapiens cathepsin L1 protein.
Length = 333
Score = 163 bits (395), Expect = 1e-39
Identities = 105/294 (35%), Positives = 149/294 (50%), Gaps = 17/294 (5%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 735
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 734 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 558
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGPCGSCWAFSATGALEGQM 151
Query: 557 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 384
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 383 RMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA--DIVNYKQGII--KYCF 216
+ N K+ V + I E+ L + VGPI +AIDA + YK+GI C
Sbjct: 212 KYNP-KYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCS 270
Query: 215 DSGLNHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
++H VL+VGYG E +N YW KN+WG +WG G+ ++ + N CG+
Sbjct: 271 SEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGI 324
>AL137742-1|CAB70900.1| 308|Homo sapiens hypothetical protein
protein.
Length = 308
Score = 161 bits (391), Expect = 3e-39
Identities = 90/248 (36%), Positives = 136/248 (54%), Gaps = 6/248 (2%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLP 726
N+ Y S+ E R +F +N+ + I +A+Y + KFSDL+++E Y L
Sbjct: 35 NRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRTIYLNTLLR 94
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKH 546
+ N K+ P E+DWR VT VK+QGMCG+CWAF+ G++E Q+ +
Sbjct: 95 KEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNVEGQWFLNQ 152
Query: 545 NELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY Y+ +C ++ K
Sbjct: 153 GTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEK 212
Query: 365 FLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSGLNH 198
V + D + E+KL L GPI +AI+A + Y+ GI + C ++H
Sbjct: 213 AKVYINDSVE-LSQNEQKLAAWLAKRGPISVAINAFGMQFYRHGISRPLRPLCSPWLIDH 271
Query: 197 AVLLVGYG 174
AVLLVGYG
Sbjct: 272 AVLLVGYG 279
>Y14734-1|CAA75029.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 153 bits (370), Expect = 1e-36
Identities = 96/290 (33%), Positives = 147/290 (50%), Gaps = 16/290 (5%)
Frame = -3
Query: 890 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 714
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFPDMTNEEFRQMMGCFRNQ 98
Query: 713 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 537
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 536 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKF 363
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN- 217
Query: 362 LVQVKDCYRYIIVYEEKLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGL 204
V + + +V K K L++ VGPI +A+DA + YK GI C L
Sbjct: 218 --SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNL 275
Query: 203 NHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
+H VL+VGYG E NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 276 DHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>BC110512-1|AAI10513.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 152 bits (369), Expect = 1e-36
Identities = 96/290 (33%), Positives = 147/290 (50%), Gaps = 16/290 (5%)
Frame = -3
Query: 890 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 714
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 713 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 537
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 536 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKF 363
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN- 217
Query: 362 LVQVKDCYRYIIVYEEKLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGL 204
V + + +V K K L++ VGPI +A+DA + YK GI C L
Sbjct: 218 --SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNL 275
Query: 203 NHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
+H VL+VGYG E NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 276 DHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>BC023504-1|AAH23504.1| 334|Homo sapiens CTSL2 protein protein.
Length = 334
Score = 152 bits (369), Expect = 1e-36
Identities = 96/290 (33%), Positives = 147/290 (50%), Gaps = 16/290 (5%)
Frame = -3
Query: 890 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 714
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 713 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 537
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 536 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKF 363
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN- 217
Query: 362 LVQVKDCYRYIIVYEEKLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGL 204
V + + +V K K L++ VGPI +A+DA + YK GI C L
Sbjct: 218 --SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNL 275
Query: 203 NHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
+H VL+VGYG E NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 276 DHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>AY358641-1|AAQ89004.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 152 bits (369), Expect = 1e-36
Identities = 96/290 (33%), Positives = 147/290 (50%), Gaps = 16/290 (5%)
Frame = -3
Query: 890 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 714
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 713 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 537
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 536 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKF 363
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN- 217
Query: 362 LVQVKDCYRYIIVYEEKLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGL 204
V + + +V K K L++ VGPI +A+DA + YK GI C L
Sbjct: 218 --SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNL 275
Query: 203 NHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
+H VL+VGYG E NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 276 DHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>AL445670-2|CAI15053.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 152 bits (369), Expect = 1e-36
Identities = 96/290 (33%), Positives = 147/290 (50%), Gaps = 16/290 (5%)
Frame = -3
Query: 890 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 714
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 713 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 537
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 536 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKF 363
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN- 217
Query: 362 LVQVKDCYRYIIVYEEKLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGL 204
V + + +V K K L++ VGPI +A+DA + YK GI C L
Sbjct: 218 --SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNL 275
Query: 203 NHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
+H VL+VGYG E NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 276 DHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>AF070448-1|AAC23598.1| 334|Homo sapiens cathepsin U protein.
Length = 334
Score = 152 bits (369), Expect = 1e-36
Identities = 96/290 (33%), Positives = 147/290 (50%), Gaps = 16/290 (5%)
Frame = -3
Query: 890 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 714
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 713 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 537
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 536 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKF 363
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN- 217
Query: 362 LVQVKDCYRYIIVYEEKLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGL 204
V + + +V K K L++ VGPI +A+DA + YK GI C L
Sbjct: 218 --SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNL 275
Query: 203 NHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
+H VL+VGYG E NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 276 DHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>AB019534-1|BAA34365.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 152 bits (369), Expect = 1e-36
Identities = 96/290 (33%), Positives = 147/290 (50%), Gaps = 16/290 (5%)
Frame = -3
Query: 890 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 714
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 713 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 537
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 536 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKF 363
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN- 217
Query: 362 LVQVKDCYRYIIVYEEKLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGL 204
V + + +V K K L++ VGPI +A+DA + YK GI C L
Sbjct: 218 --SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNL 275
Query: 203 NHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
+H VL+VGYG E NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 276 DHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>AB001928-1|BAA25909.1| 334|Homo sapiens cathepsin V protein.
Length = 334
Score = 152 bits (369), Expect = 1e-36
Identities = 96/290 (33%), Positives = 147/290 (50%), Gaps = 16/290 (5%)
Frame = -3
Query: 890 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 714
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 713 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 537
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 536 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNKF 363
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPEN- 217
Query: 362 LVQVKDCYRYIIVYEEKLKDLLR---LVGPIPMAIDA--ADIVNYKQGII--KYCFDSGL 204
V + + +V K K L++ VGPI +A+DA + YK GI C L
Sbjct: 218 --SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNL 275
Query: 203 NHAVLLVGYGVE----NNIPYWTFKNTWGTDWGEDGFFRV-QQNINACGM 69
+H VL+VGYG E NN YW KN+WG +WG +G+ ++ + N CG+
Sbjct: 276 DHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325
>BC048255-1|AAH48255.1| 376|Homo sapiens cathepsin W protein.
Length = 376
Score = 149 bits (360), Expect = 2e-35
Identities = 88/306 (28%), Positives = 151/306 (49%), Gaps = 29/306 (9%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNLNEIINKNQND--SAKYEINKFSDLSKDETIAKYTGLSLP 726
N++Y S E R IF HNL + + D +A++ + FSDL+++E Y
Sbjct: 50 NRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAA 109
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIK 549
+ + I ++P P DWR++ ++ +K+Q C CWA A G++E+ + I
Sbjct: 110 GGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRIS 169
Query: 548 HNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSN 369
+ +++S Q+++DC GC+GG + AF ++ G+ E DYP++ R +
Sbjct: 170 FWDFVDVSVQELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPK 229
Query: 368 KF--LVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSG 207
K+ + ++D + + E ++ L GPI + I+ + Y++G+IK C
Sbjct: 230 KYQKVAWIQD-FIMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQL 288
Query: 206 LNHAVLLVGYG---VENNI-----------------PYWTFKNTWGTDWGEDGFFRVQQN 87
++H+VLLVG+G E I PYW KN+WG WGE G+FR+ +
Sbjct: 289 VDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRG 348
Query: 86 INACGM 69
N CG+
Sbjct: 349 SNTCGI 354
>AF055903-1|AAC32181.1| 376|Homo sapiens cathepsin W protein.
Length = 376
Score = 146 bits (355), Expect = 7e-35
Identities = 87/306 (28%), Positives = 150/306 (49%), Gaps = 29/306 (9%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNLNEIINKNQND--SAKYEINKFSDLSKDETIAKYTGLSLP 726
N++Y S E R IF HNL + + D +A++ + FSDL+++E Y
Sbjct: 50 NRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAA 109
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIK 549
+ + I ++P P DWR++ ++ +K+Q C CWA A G++E+ + I
Sbjct: 110 GGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRIS 169
Query: 548 HNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSN 369
+ +++S +++DC GC+GG + AF ++ G+ E DYP++ R +
Sbjct: 170 FWDFVDVSVHELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPK 229
Query: 368 KF--LVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSG 207
K+ + ++D + + E ++ L GPI + I+ + Y++G+IK C
Sbjct: 230 KYQKVAWIQD-FIMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQL 288
Query: 206 LNHAVLLVGYG---VENNI-----------------PYWTFKNTWGTDWGEDGFFRVQQN 87
++H+VLLVG+G E I PYW KN+WG WGE G+FR+ +
Sbjct: 289 VDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRG 348
Query: 86 INACGM 69
N CG+
Sbjct: 349 SNTCGI 354
>AF015954-1|AAB82457.1| 376|Homo sapiens lymphopain protein.
Length = 376
Score = 146 bits (355), Expect = 7e-35
Identities = 87/306 (28%), Positives = 150/306 (49%), Gaps = 29/306 (9%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNLNEIINKNQND--SAKYEINKFSDLSKDETIAKYTGLSLP 726
N++Y S E R IF HNL + + D +A++ + FSDL+++E Y
Sbjct: 50 NRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAA 109
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIK 549
+ + I ++P P DWR++ ++ +K+Q C CWA A G++E+ + I
Sbjct: 110 GGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRIS 169
Query: 548 HNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSN 369
+ +++S +++DC GC+GG + AF ++ G+ E DYP++ R +
Sbjct: 170 FWDFVDVSVHELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPK 229
Query: 368 KF--LVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSG 207
K+ + ++D + + E ++ L GPI + I+ + Y++G+IK C
Sbjct: 230 KYQKVAWIQD-FIMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQL 288
Query: 206 LNHAVLLVGYG---VENNI-----------------PYWTFKNTWGTDWGEDGFFRVQQN 87
++H+VLLVG+G E I PYW KN+WG WGE G+FR+ +
Sbjct: 289 VDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRG 348
Query: 86 INACGM 69
N CG+
Sbjct: 349 SNTCGI 354
>AF013611-1|AAB82449.1| 376|Homo sapiens lymphopain protein.
Length = 376
Score = 146 bits (355), Expect = 7e-35
Identities = 87/306 (28%), Positives = 150/306 (49%), Gaps = 29/306 (9%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNLNEIINKNQND--SAKYEINKFSDLSKDETIAKYTGLSLP 726
N++Y S E R IF HNL + + D +A++ + FSDL+++E Y
Sbjct: 50 NRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFGQLYGYRRAA 109
Query: 725 TQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIK 549
+ + I ++P P DWR++ ++ +K+Q C CWA A G++E+ + I
Sbjct: 110 GGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCWAMAAAGNIETLWRIS 169
Query: 548 HNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSN 369
+ +++S +++DC GC+GG + AF ++ G+ E DYP++ R +
Sbjct: 170 FWDFVDVSVHELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKDYPFQGKVRAHRCHPK 229
Query: 368 KF--LVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAADIVNYKQGIIK----YCFDSG 207
K+ + ++D + + E ++ L GPI + I+ + Y++G+IK C
Sbjct: 230 KYQKVAWIQD-FIMLQNNEHRIAQYLATYGPITVTINMKPLQLYRKGVIKATPTTCDPQL 288
Query: 206 LNHAVLLVGYG---VENNI-----------------PYWTFKNTWGTDWGEDGFFRVQQN 87
++H+VLLVG+G E I PYW KN+WG WGE G+FR+ +
Sbjct: 289 VDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRG 348
Query: 86 INACGM 69
N CG+
Sbjct: 349 SNTCGI 354
>Y18461-1|CAA77179.1| 166|Homo sapiens cathepsin H protein.
Length = 166
Score = 134 bits (325), Expect = 3e-31
Identities = 68/166 (40%), Positives = 95/166 (57%), Gaps = 7/166 (4%)
Frame = -3
Query: 608 CGACWAFATLGSLESQFAIKHNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMG 435
CG+CW F+T G+LES AI ++++L+EQQ++DC DF + GC GGL AFE I+
Sbjct: 1 CGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNK 60
Query: 434 GVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA- 258
G+ E YPY+ + C+ K + VKD I EE + + + L P+ A +
Sbjct: 61 GIMGEDTYPYQGKDGYCKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEVTQ 120
Query: 257 DIVNYKQGIIK--YCFDS--GLNHAVLLVGYGVENNIPYWTFKNTW 132
D + Y+ GI C + +NHAVL VGYG EN IPYW KN+W
Sbjct: 121 DFMMYRTGIYSSTSCHKTPDKVNHAVLAVGYGEENGIPYWIVKNSW 166
>Y18462-1|CAA77180.1| 175|Homo sapiens cathepsin L protein.
Length = 175
Score = 132 bits (318), Expect = 2e-30
Identities = 75/176 (42%), Positives = 99/176 (56%), Gaps = 10/176 (5%)
Frame = -3
Query: 635 VTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV--DAGCNGGLLHT 462
VT VKNQG CG+CWAF+ G+LE Q K LI+LSEQ ++DC + GCNGGL+
Sbjct: 1 VTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDY 60
Query: 461 AFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGP 282
AF+ + GG+ E YPYEA +C+ N K+ V + I E+ L + VGP
Sbjct: 61 AFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQEKALMKAVATVGP 119
Query: 281 IPMAIDAA--DIVNYKQGII--KYCFDSGLNHAVLLVGYGVE----NNIPYWTFKN 138
I +AIDA + YK+GI C ++H VL+VGYG E +N YW KN
Sbjct: 120 ISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESSESDNNKYWLVKN 175
>U07374-1|AAB60643.2| 267|Homo sapiens cathepsin S protein.
Length = 267
Score = 125 bits (302), Expect = 2e-28
Identities = 73/223 (32%), Positives = 119/223 (53%), Gaps = 11/223 (4%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y + E+ R I++ NL ++ N S Y++ N D++ +E ++ + L
Sbjct: 37 KQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLTSSLR 96
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P+Q Q + P P DWR VT VK QG CGACWAF+ +G+LE+Q +
Sbjct: 97 VPSQWQR--NITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKL 154
Query: 551 KHNELINLSEQQMIDCD---FVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 381
K +L+ LS Q ++DC + + GCNGG + TAF+ II G+ ++ YPY+A + C+
Sbjct: 155 KTGKLVTLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQ 214
Query: 380 MNSNKFLVQVKDCYRYI-IVY--EEKLKDLLRLVGPIPMAIDA 261
+S + C +Y + Y E+ LK+ + GP+ + +DA
Sbjct: 215 YDSK---YRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDA 254
>X87212-1|CAA60671.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 120 bits (290), Expect = 5e-27
Identities = 88/304 (28%), Positives = 148/304 (48%), Gaps = 22/304 (7%)
Frame = -3
Query: 887 SSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNF 708
S E R +K + HN + IN Q ++ L+ + I + G S
Sbjct: 159 SQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKP 217
Query: 707 CKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE 540
+ + Q P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N
Sbjct: 218 APLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNN 277
Query: 539 LIN--LSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
LS Q+++ C GC GG + + G+ E+ +PY ++ C+M +
Sbjct: 278 SQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDC 337
Query: 365 FLVQVKDCYRYIIVYEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC----- 219
F + Y Y+ + + L LV GP+ +A + D ++YK+GI +
Sbjct: 338 FRYYSSE-YHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDP 396
Query: 218 FDSG--LNHAVLLVGYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELA 54
F+ NHAVLLVGYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A
Sbjct: 397 FNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVA 456
Query: 53 STAV 42
+T +
Sbjct: 457 ATPI 460
>U79415-1|AAC51341.1| 463|Homo sapiens prepro dipeptidyl peptidase I
protein.
Length = 463
Score = 120 bits (290), Expect = 5e-27
Identities = 88/304 (28%), Positives = 148/304 (48%), Gaps = 22/304 (7%)
Frame = -3
Query: 887 SSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNF 708
S E R +K + HN + IN Q ++ L+ + I + G S
Sbjct: 159 SQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKP 217
Query: 707 CKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE 540
+ + Q P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N
Sbjct: 218 APLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNN 277
Query: 539 LIN--LSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
LS Q+++ C GC GG + + G+ E+ +PY ++ C+M +
Sbjct: 278 SQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDC 337
Query: 365 FLVQVKDCYRYIIVYEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC----- 219
F + Y Y+ + + L LV GP+ +A + D ++YK+GI +
Sbjct: 338 FRYYSSE-YHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDP 396
Query: 218 FDSG--LNHAVLLVGYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELA 54
F+ NHAVLLVGYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A
Sbjct: 397 FNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVA 456
Query: 53 STAV 42
+T +
Sbjct: 457 ATPI 460
>AK223038-1|BAD96758.1| 463|Homo sapiens cathepsin C isoform a
preproprotein variant protein.
Length = 463
Score = 120 bits (290), Expect = 5e-27
Identities = 88/304 (28%), Positives = 148/304 (48%), Gaps = 22/304 (7%)
Frame = -3
Query: 887 SSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNF 708
S E R +K + HN + IN Q ++ L+ + I + G S
Sbjct: 159 SQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKP 217
Query: 707 CKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE 540
+ + Q P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N
Sbjct: 218 APLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNN 277
Query: 539 LIN--LSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
LS Q+++ C GC GG + + G+ E+ +PY ++ C+M +
Sbjct: 278 SQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDC 337
Query: 365 FLVQVKDCYRYIIVYEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC----- 219
F + Y Y+ + + L LV GP+ +A + D ++YK+GI +
Sbjct: 338 FRYYSSE-YHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDP 396
Query: 218 FDSG--LNHAVLLVGYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELA 54
F+ NHAVLLVGYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A
Sbjct: 397 FNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVA 456
Query: 53 STAV 42
+T +
Sbjct: 457 ATPI 460
>AF234263-1|AAL48191.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 120 bits (290), Expect = 5e-27
Identities = 88/304 (28%), Positives = 148/304 (48%), Gaps = 22/304 (7%)
Frame = -3
Query: 887 SSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNF 708
S E R +K + HN + IN Q ++ L+ + I + G S
Sbjct: 159 SQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKP 217
Query: 707 CKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE 540
+ + Q P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N
Sbjct: 218 APLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNN 277
Query: 539 LIN--LSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
LS Q+++ C GC GG + + G+ E+ +PY ++ C+M +
Sbjct: 278 SQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDC 337
Query: 365 FLVQVKDCYRYIIVYEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC----- 219
F + Y Y+ + + L LV GP+ +A + D ++YK+GI +
Sbjct: 338 FRYYSSE-YHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDP 396
Query: 218 FDSG--LNHAVLLVGYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELA 54
F+ NHAVLLVGYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A
Sbjct: 397 FNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVA 456
Query: 53 STAV 42
+T +
Sbjct: 457 ATPI 460
>AF525032-1|AAQ08887.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 120 bits (288), Expect = 9e-27
Identities = 88/304 (28%), Positives = 148/304 (48%), Gaps = 22/304 (7%)
Frame = -3
Query: 887 SSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNF 708
S E R +K + HN + IN Q ++ L+ + I + G S
Sbjct: 159 SQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKP 217
Query: 707 CKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE 540
+ + Q P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N
Sbjct: 218 APLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNN 277
Query: 539 LIN--LSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
LS Q+++ C GC GG + + G+ E+ +PY ++ C+M +
Sbjct: 278 SQTPILSPQEVVSCSQHAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDC 337
Query: 365 FLVQVKDCYRYIIVYEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC----- 219
F + Y Y+ + + L LV GP+ +A + D ++YK+GI +
Sbjct: 338 FRYYSSE-YHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDP 396
Query: 218 FDSG--LNHAVLLVGYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELA 54
F+ NHAVLLVGYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A
Sbjct: 397 FNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVA 456
Query: 53 STAV 42
+T +
Sbjct: 457 ATPI 460
>AF234264-1|AAL48192.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 117 bits (281), Expect = 7e-26
Identities = 87/304 (28%), Positives = 147/304 (48%), Gaps = 22/304 (7%)
Frame = -3
Query: 887 SSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNF 708
S E R +K + HN + IN Q ++ L+ + I + G S
Sbjct: 159 SQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKP 217
Query: 707 CKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE 540
+ + Q P + WR +N V+ V+NQ CG+C++FA++G LE++ I N
Sbjct: 218 APLTAEIQQKILHLPTSWYWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNN 277
Query: 539 LIN--LSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
LS Q+++ C GC GG + + G+ E+ +PY ++ C+M +
Sbjct: 278 SQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDC 337
Query: 365 FLVQVKDCYRYIIVYEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC----- 219
F + Y Y+ + + L LV GP+ +A + D ++YK+GI +
Sbjct: 338 FRYYSSE-YHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDP 396
Query: 218 FDSG--LNHAVLLVGYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELA 54
F+ NHAVLLVGYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A
Sbjct: 397 FNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVA 456
Query: 53 STAV 42
+T +
Sbjct: 457 ATPI 460
>AF254757-1|AAL48195.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 116 bits (279), Expect = 1e-25
Identities = 87/304 (28%), Positives = 147/304 (48%), Gaps = 22/304 (7%)
Frame = -3
Query: 887 SSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNF 708
S E R +K + HN + IN Q ++ L+ + I + G S
Sbjct: 159 SQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKP 217
Query: 707 CKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE 540
+ + Q P +DWR +N V+ V+NQ CG+C++FA++G LE++ I N
Sbjct: 218 APLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNN 277
Query: 539 LIN--LSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 366
LS Q+++ GC GG + + G+ E+ +PY ++ C+M +
Sbjct: 278 SQTPILSPQEVVSYSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDC 337
Query: 365 FLVQVKDCYRYIIVYEEKLKDLL---RLV--GPIPMAIDAAD-IVNYKQGIIKYC----- 219
F + Y Y+ + + L LV GP+ +A + D ++YK+GI +
Sbjct: 338 FRYYSSE-YHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDP 396
Query: 218 FDSG--LNHAVLLVGYGVEN--NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN-ELA 54
F+ NHAVLLVGYG ++ + YW KN+WGT WGE+G+FR+++ + C + + +A
Sbjct: 397 FNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVA 456
Query: 53 STAV 42
+T +
Sbjct: 457 ATPI 460
>AL355860-2|CAI12796.1| 258|Homo sapiens cathepsin K protein.
Length = 258
Score = 114 bits (275), Expect = 4e-25
Identities = 58/164 (35%), Positives = 92/164 (56%), Gaps = 5/164 (3%)
Frame = -3
Query: 896 KNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLS 732
K Y+++V+++ R I++ NL I N S YE+ N D++ +E + K TGL
Sbjct: 94 KQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLK 153
Query: 731 LPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAI 552
+P + + + G+ P D+R+ VT VKNQG CG+CWAF+++G+LE Q
Sbjct: 154 VPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKK 213
Query: 551 KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLE 420
K +L+NLS Q ++DC + GC GG + AF+ + K G+ E
Sbjct: 214 KTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSE 257
>AL160279-2|CAI16307.1| 225|Homo sapiens cathepsin L1 protein.
Length = 225
Score = 103 bits (247), Expect = 9e-22
Identities = 67/189 (35%), Positives = 94/189 (49%), Gaps = 10/189 (5%)
Frame = -3
Query: 899 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 735
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 734 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 558
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 557 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNN- 387
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATVSGA 211
Query: 386 -CRMNSNKF 363
C +S+ F
Sbjct: 212 PCHHSSSAF 220
>AF217997-1|AAG17239.1| 151|Homo sapiens unknown protein.
Length = 151
Score = 86.6 bits (205), Expect = 1e-16
Identities = 51/140 (36%), Positives = 74/140 (52%), Gaps = 9/140 (6%)
Frame = -3
Query: 461 AFEAIIKMGGVQLESDYPYEADNNNCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGP 282
AF+ + GG+ E YPYEA +C+ N K+ V + I E+ L + VGP
Sbjct: 4 AFQYVQDNGGLDSEESYPYEATEESCKYNP-KYSVANDTGFVDIPKQEKALMKAVATVGP 62
Query: 281 IPMAIDAA--DIVNYKQGII--KYCFDSGLNHAVLLVGYGVEN----NIPYWTFKNTWGT 126
I +AIDA + YK+GI C ++H VL+VGYG E+ N YW KN+WG
Sbjct: 63 ISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGE 122
Query: 125 DWGEDGFFRV-QQNINACGM 69
+WG G+ ++ + N CG+
Sbjct: 123 EWGMGGYVKMAKDRRNHCGI 142
>BT019915-1|AAV38718.1| 303|Homo sapiens cathepsin Z protein.
Length = 303
Score = 79.4 bits (187), Expect = 2e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -3
Query: 680 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 528
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 527 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 354
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 353 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 216
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 215 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 96
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>BC042168-1|AAH42168.1| 303|Homo sapiens cathepsin Z protein.
Length = 303
Score = 79.4 bits (187), Expect = 2e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -3
Query: 680 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 528
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 527 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 354
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 353 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 216
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 215 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 96
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>AL109840-6|CAC09370.1| 303|Homo sapiens cathepsin Z protein.
Length = 303
Score = 79.4 bits (187), Expect = 2e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -3
Query: 680 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 528
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 527 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 354
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 353 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 216
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 215 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 96
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>AF136276-1|AAF13148.1| 303|Homo sapiens cathepsin Z precursor
protein.
Length = 303
Score = 79.4 bits (187), Expect = 2e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -3
Query: 680 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 528
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 527 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 354
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 353 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 216
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 215 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 96
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>AF136273-1|AAF13145.1| 303|Homo sapiens cathepsin Z precursor
protein.
Length = 303
Score = 79.4 bits (187), Expect = 2e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -3
Query: 680 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 528
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 527 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 354
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 353 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 216
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 215 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 96
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>AF032906-1|AAC39839.1| 303|Homo sapiens cathepsin Z precursor
protein.
Length = 303
Score = 79.4 bits (187), Expect = 2e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -3
Query: 680 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 528
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 527 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 354
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 353 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 216
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 215 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 96
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>AF009923-1|AAC63141.1| 293|Homo sapiens preprocathepsin P protein.
Length = 293
Score = 79.4 bits (187), Expect = 2e-14
Identities = 63/220 (28%), Positives = 103/220 (46%), Gaps = 25/220 (11%)
Frame = -3
Query: 680 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 528
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 49 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 108
Query: 527 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 354
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 109 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 165
Query: 353 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 216
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 166 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 225
Query: 215 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 96
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 226 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 265
>AF073890-1|AAC61477.1| 303|Homo sapiens cathepsin X precursor
protein.
Length = 303
Score = 78.6 bits (185), Expect = 3e-14
Identities = 61/219 (27%), Positives = 100/219 (45%), Gaps = 24/219 (10%)
Frame = -3
Query: 680 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 528
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 527 SEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQV 351
S Q +IDC C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCGN-RGSCEGGNDLSVWD-YAHQHGISDETCNNYQAKDQECDKFNQCGTCNEF 176
Query: 350 KDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCFD 213
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 177 KECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDT 236
Query: 212 SGLNHAVLLVGYGVENNIPYWTFKNTWGTDWGEDGFFRV 96
+ +NH V + G+G+ + YW +N+WG WGE G+ R+
Sbjct: 237 TYINHVVSVAGWGISDGTEYWIVRNSWGEPWGERGWLRI 275
>M14221-1|AAA52129.1| 339|Homo sapiens CTSB protein.
Length = 339
Score = 74.1 bits (174), Expect = 6e-13
Identities = 29/81 (35%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -3
Query: 287 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTWGTDWGE 114
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W TDWG+
Sbjct: 247 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 306
Query: 113 DGFFRVQQNINACGMRNELAS 51
+GFF++ + + CG+ +E+ +
Sbjct: 307 NGFFKILRGQDHCGIESEVVA 327
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = -3
Query: 674 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 513
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 512 IDC--DFVDAGCNGG 474
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>M13230-1|AAA52125.1| 209|Homo sapiens CTSB protein.
Length = 209
Score = 74.1 bits (174), Expect = 6e-13
Identities = 29/81 (35%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -3
Query: 287 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTWGTDWGE 114
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W TDWG+
Sbjct: 117 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 176
Query: 113 DGFFRVQQNINACGMRNELAS 51
+GFF++ + + CG+ +E+ +
Sbjct: 177 NGFFKILRGQDHCGIESEVVA 197
>L16510-1|AAC37547.1| 339|Homo sapiens cathepsin B protein.
Length = 339
Score = 74.1 bits (174), Expect = 6e-13
Identities = 29/81 (35%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -3
Query: 287 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTWGTDWGE 114
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W TDWG+
Sbjct: 247 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 306
Query: 113 DGFFRVQQNINACGMRNELAS 51
+GFF++ + + CG+ +E+ +
Sbjct: 307 NGFFKILRGQDHCGIESEVVA 327
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = -3
Query: 674 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 513
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 512 IDC--DFVDAGCNGG 474
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>BC095408-1|AAH95408.1| 339|Homo sapiens cathepsin B protein.
Length = 339
Score = 74.1 bits (174), Expect = 6e-13
Identities = 29/81 (35%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -3
Query: 287 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTWGTDWGE 114
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W TDWG+
Sbjct: 247 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 306
Query: 113 DGFFRVQQNINACGMRNELAS 51
+GFF++ + + CG+ +E+ +
Sbjct: 307 NGFFKILRGQDHCGIESEVVA 327
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = -3
Query: 674 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 513
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 512 IDC--DFVDAGCNGG 474
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>BC010240-1|AAH10240.1| 339|Homo sapiens cathepsin B protein.
Length = 339
Score = 74.1 bits (174), Expect = 6e-13
Identities = 29/81 (35%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
Frame = -3
Query: 287 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTWGTDWGE 114
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W TDWG+
Sbjct: 247 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGD 306
Query: 113 DGFFRVQQNINACGMRNELAS 51
+GFF++ + + CG+ +E+ +
Sbjct: 307 NGFFKILRGQDHCGIESEVVA 327
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = -3
Query: 674 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 513
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 512 IDC--DFVDAGCNGG 474
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>BC025419-1|AAH25419.1| 297|Homo sapiens CTSZ protein protein.
Length = 297
Score = 69.7 bits (163), Expect = 1e-11
Identities = 59/212 (27%), Positives = 97/212 (45%), Gaps = 25/212 (11%)
Frame = -3
Query: 680 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHNEL---INL 528
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 527 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC-RMNSNKFLVQ 354
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C + N +
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQECDKFNQCGTCNE 175
Query: 353 VKDCY--RYIIVYE----------EKLKDLLRLVGPIPMAIDAAD-IVNYKQGII-KYCF 216
K+C+ R ++ EK+ + GPI I A + + NY GI +Y
Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQD 235
Query: 215 DSGLNHAVLLVGYGVENNIPYWTFKNTWGTDW 120
+ +NH V + G+G+ + YW +N+WG W
Sbjct: 236 TTYINHVVSVAGWGISDGTEYWIVRNSWGEPW 267
>BC070278-1|AAH70278.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/222 (27%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Frame = -3
Query: 620 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 450
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 449 IIKMGGVQLESDYPY----EADNNNCRMNS--------------------NKFLVQVKDC 342
+ K G V + YP A NN C M S + + Q
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPP 354
Query: 341 YRYIIVYEEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYCFDSGLN---------HAV 192
YR E +K++++ GP+ + D +YK GI ++ + HAV
Sbjct: 355 YRVSSNETEIMKEIMQN-GPVQAIMQVHEDFFHYKTGIYRHVTSTNKESEKYRKLQTHAV 413
Query: 191 LLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 81
L G+G +W N+WG WGE+G+FR+ + +N
Sbjct: 414 KLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455
>BC064633-1|AAH64633.1| 467|Homo sapiens tubulointerstitial nephritis
antigen-like 1 protein.
Length = 467
Score = 61.3 bits (142), Expect = 5e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -3
Query: 782 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 612
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 611 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 441
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 440 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 324
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 323 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 192
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 191 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 63
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AY358421-1|AAQ88787.1| 467|Homo sapiens LCN7 protein.
Length = 467
Score = 61.3 bits (142), Expect = 5e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -3
Query: 782 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 612
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 611 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 441
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 440 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 324
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 323 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 192
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 191 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 63
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AL589946-2|CAH70302.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/222 (27%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Frame = -3
Query: 620 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 450
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 449 IIKMGGVQLESDYPY----EADNNNCRMNS--------------------NKFLVQVKDC 342
+ K G V + YP A NN C M S + + Q
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPP 354
Query: 341 YRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKYCFDSGLN---------HAV 192
YR E +K++++ GP+ + D +YK GI ++ + HAV
Sbjct: 355 YRVSSNETEIMKEIMQN-GPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAV 413
Query: 191 LLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 81
L G+G +W N+WG WGE+G+FR+ + +N
Sbjct: 414 KLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455
>AL359380-5|CAI16272.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/222 (27%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Frame = -3
Query: 620 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 450
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 449 IIKMGGVQLESDYPY----EADNNNCRMNS--------------------NKFLVQVKDC 342
+ K G V + YP A NN C M S + + Q
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPP 354
Query: 341 YRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKYCFDSGLN---------HAV 192
YR E +K++++ GP+ + D +YK GI ++ + HAV
Sbjct: 355 YRVSSNETEIMKEIMQN-GPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAV 413
Query: 191 LLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 81
L G+G +W N+WG WGE+G+FR+ + +N
Sbjct: 414 KLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455
>AK075398-1|BAC11596.1| 467|Homo sapiens protein ( Homo sapiens cDNA
PSEC0088 fis, clone PLACE1001098, highly similar to
P3ECSL; glucocorticoid-inducible protein. ).
Length = 467
Score = 61.3 bits (142), Expect = 5e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -3
Query: 782 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 612
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 611 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 441
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 440 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 324
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 323 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 192
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 191 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 63
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AF236155-1|AAG40154.1| 467|Homo sapiens tubulointerstitial nephritis
antigen-related protein protein.
Length = 467
Score = 61.3 bits (142), Expect = 5e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -3
Query: 782 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 612
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 611 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 441
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 440 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 324
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 323 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 192
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 191 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 63
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AF236150-1|AAG38876.1| 467|Homo sapiens tubulointerstitial nephritis
antigen-related protein precursor protein.
Length = 467
Score = 61.3 bits (142), Expect = 5e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -3
Query: 782 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 612
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 611 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 441
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 440 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 324
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 323 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 192
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 191 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 63
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AF205436-1|AAG33699.1| 467|Homo sapiens oxidized-LDL responsive gene
2 protein.
Length = 467
Score = 61.3 bits (142), Expect = 5e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -3
Query: 782 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 612
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 611 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 441
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 440 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 324
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 323 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 192
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 191 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 63
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AB050719-1|BAB18727.1| 467|Homo sapiens glucocorticoid-inducible
protein protein.
Length = 467
Score = 61.3 bits (142), Expect = 5e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -3
Query: 782 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 612
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 611 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 441
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 440 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 324
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 323 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 192
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 191 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 63
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AB050716-1|BAB18636.1| 467|Homo sapiens glucocorticoid-inducible
protein protein.
Length = 467
Score = 61.3 bits (142), Expect = 5e-09
Identities = 71/288 (24%), Positives = 114/288 (39%), Gaps = 48/288 (16%)
Frame = -3
Query: 782 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 612
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 611 MCGACWAFATLGSLESQFAIKHNELIN--LSEQQMIDCD-FVDAGCNGGLLHTAFEAIIK 441
C WAF+T + +I + LS Q ++ CD GC GG L A+ ++
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCRGGRLDGAWW-FLR 283
Query: 440 MGGVQLESDYPYEADNNN-------CRMNSNKF--------------LVQVKDCYRYIIV 324
GV + YP+ + C M+S V D Y+ V
Sbjct: 284 RRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQVTPV 343
Query: 323 Y------EEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC---------FDSGLNHAV 192
Y +E +K+L+ GP+ ++ D YK GI + + H+V
Sbjct: 344 YRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPVSLGRPERYRRHGTHSV 402
Query: 191 LLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINACGMRN 63
+ G+G E + YWT N+WG WGE G FR+ + +N C + +
Sbjct: 403 KITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNECDIES 450
>AB022277-1|BAA84949.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 61.3 bits (142), Expect = 5e-09
Identities = 61/222 (27%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Frame = -3
Query: 620 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 450
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 449 IIKMGGVQLESDYPY----EADNNNCRMNS--------------------NKFLVQVKDC 342
+ K G V + YP A NN C M S + + Q
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMASRSDGRGKRHATKPCPNNVEKSNRIYQCSPP 354
Query: 341 YRYIIVYEEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYCFDSGLN---------HAV 192
YR E +K++++ GP+ + D +YK GI ++ + HAV
Sbjct: 355 YRVSSNETEIMKEIMQN-GPVQAIMQVHEDFFHYKTGIYRHVTSTNKESEKYRKLQTHAV 413
Query: 191 LLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 81
L G+G +W N+WG WGE+G+FR+ + +N
Sbjct: 414 KLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 455
>AF195116-1|AAF08931.1| 476|Homo sapiens tubulointerstitial
nephritis antigen isoform TIN-ag protein.
Length = 476
Score = 60.1 bits (139), Expect = 1e-08
Identities = 61/222 (27%), Positives = 90/222 (40%), Gaps = 42/222 (18%)
Frame = -3
Query: 620 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 450
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 449 IIKMGGVQLESDYPY----EADNNNCRMNS--------------------NKFLVQVKDC 342
+ K G V + YP A NN C M S + + Q
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMASRSDGRGKRDATKPCPNNVEKSNRIYQCSPP 354
Query: 341 YRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKYCFDSGLN---------HAV 192
YR E +K++++ GP+ + D +YK GI ++ + HAV
Sbjct: 355 YRVSSNETEIMKEIMQN-GPVQAIMQVREDFFHYKTGIYRHVTSTNKESEKYRKLQTHAV 413
Query: 191 LLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 81
L G+G +W N WG WGE+G+FR+ + +N
Sbjct: 414 KLTGWGTLRGAQGQKEKFWIAANFWGKSWGENGYFRILRGVN 455
>X05256-1|CAA28877.1| 42|Homo sapiens protein ( Human mRNA
fragment for cathepsin L N-terminal/fragment. ).
Length = 42
Score = 54.0 bits (124), Expect = 7e-07
Identities = 21/38 (55%), Positives = 25/38 (65%)
Frame = -3
Query: 674 KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQ 561
+ P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQ 38
>BC009048-1|AAH09048.1| 218|Homo sapiens TINAGL1 protein protein.
Length = 218
Score = 51.2 bits (117), Expect = 5e-06
Identities = 36/124 (29%), Positives = 58/124 (46%), Gaps = 15/124 (12%)
Frame = -3
Query: 389 NCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC-- 219
N +N+N + QV YR +E +K+L+ GP+ ++ D YK GI +
Sbjct: 80 NSYVNNND-IYQVTPVYRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYKGGIYSHTPV 137
Query: 218 -------FDSGLNHAVLLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINAC 75
+ H+V + G+G E + YWT N+WG WGE G FR+ + +N C
Sbjct: 138 SLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNEC 197
Query: 74 GMRN 63
+ +
Sbjct: 198 DIES 201
>AK027839-1|BAB55403.1| 218|Homo sapiens protein ( Homo sapiens
cDNA FLJ14933 fis, clone PLACE1009861, weakly similar to
CATHEPSIN B-LIKE CYSTEINE PROTEINASE 6 PRECURSOR (EC
3.4.22.-). ).
Length = 218
Score = 49.6 bits (113), Expect = 2e-05
Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 15/124 (12%)
Frame = -3
Query: 389 NCRMNSNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDA-ADIVNYKQGIIKYC-- 219
N +N+N + QV YR +E +K+L+ GP+ ++ D Y+ GI +
Sbjct: 80 NSYVNNND-IYQVTPVYRLGSNDKEIMKELMEN-GPVQALMEVHEDFFLYEGGIYSHTPV 137
Query: 218 -------FDSGLNHAVLLVGYGVEN-----NIPYWTFKNTWGTDWGEDGFFRVQQNINAC 75
+ H+V + G+G E + YWT N+WG WGE G FR+ + +N C
Sbjct: 138 SLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVNEC 197
Query: 74 GMRN 63
+ +
Sbjct: 198 DIES 201
>Y18460-1|CAA77178.1| 195|Homo sapiens cathepsin B protein.
Length = 195
Score = 44.8 bits (101), Expect = 4e-04
Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Frame = -3
Query: 287 GPIPMAIDA-ADIVNYKQGIIKYCFDSGLN-HAVLLVGYGVENNIPYWTFKNTW 132
GP+ A +D + YK G+ ++ + HA+ ++G+GVEN PYW N+W
Sbjct: 141 GPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW 194
Score = 39.9 bits (89), Expect = 0.012
Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Frame = -3
Query: 608 CGACWAFATLGSLESQFAIKHNELINLSEQQMIDC--DFVDAGCNGG 474
CG+CWAF + ++ + I N + +S + ++ C GCNGG
Sbjct: 1 CGSCWAFGAVEAISDRICIHTNVSVEVSAEDLLTCCGSMCGDGCNGG 47
>AL589946-1|CAH70301.1| 155|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 155
Score = 44.8 bits (101), Expect = 4e-04
Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 15/113 (13%)
Frame = -3
Query: 374 SNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKYCFDSGLN- 201
SN+ + Q YR E +K++++ GP+ + D +YK GI ++ +
Sbjct: 24 SNR-IYQCSPPYRVSSNETEIMKEIMQN-GPVQAIMQVREDFFHYKTGIYRHVTSTNKES 81
Query: 200 --------HAVLLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 81
HAV L G+G +W N+WG WGE+G+FR+ + +N
Sbjct: 82 EKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRILRGVN 134
>AF195117-1|AAF08932.1| 333|Homo sapiens tubulointerstitial
nephritis antigen isoform TIN2 protein.
Length = 333
Score = 44.8 bits (101), Expect = 4e-04
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 15/113 (13%)
Frame = -3
Query: 374 SNKFLVQVKDCYRYIIVYEEKLKDLLRLVGPIPMAIDAA-DIVNYKQGIIKYCFDSGLN- 201
SN+ + Q YR E +K++++ GP+ + D +YK GI ++ +
Sbjct: 202 SNR-IYQCSPPYRVSSNETEIMKEIMQN-GPVQAIMQVREDFFHYKTGIYRHVTSTNKES 259
Query: 200 --------HAVLLVGYGVENNIP-----YWTFKNTWGTDWGEDGFFRVQQNIN 81
HAV L G+G +W N WG WGE+G+FR+ + +N
Sbjct: 260 EKYRKLQTHAVKLTGWGTRRGAQGQKEKFWIAANFWGKSWGENGYFRILRGVN 312
>AK074124-1|BAB84950.1| 284|Homo sapiens FLJ00196 protein protein.
Length = 284
Score = 33.5 bits (73), Expect = 1.1
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 4/73 (5%)
Frame = -3
Query: 641 NKVTSVKNQGMCGACWAFATLGSLESQFAIK---HNELINLSEQQMIDCD-FVDAGCNGG 474
N + +QG C WAF+T + +I H + LS Q ++ CD GC GG
Sbjct: 81 NLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPV-LSPQNLLSCDTHQQQGCRGG 139
Query: 473 LLHTAFEAIIKMG 435
L A+ + + G
Sbjct: 140 RLDGAWWFLRRRG 152
>BC089428-1|AAH89428.1| 1192|Homo sapiens PLEKHG1 protein protein.
Length = 1192
Score = 30.7 bits (66), Expect = 7.5
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = -3
Query: 569 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 462
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1096 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1130
>AL450339-2|CAI12939.1| 1385|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 1
protein.
Length = 1385
Score = 30.7 bits (66), Expect = 7.5
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = -3
Query: 569 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 462
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1289 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1323
>AL035086-3|CAI42790.1| 1385|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 1
protein.
Length = 1385
Score = 30.7 bits (66), Expect = 7.5
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = -3
Query: 569 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 462
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1289 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1323
>AB033035-1|BAA86523.1| 1113|Homo sapiens KIAA1209 protein protein.
Length = 1113
Score = 30.7 bits (66), Expect = 7.5
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = -3
Query: 569 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 462
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1017 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1051
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 128,062,083
Number of Sequences: 237096
Number of extensions: 2711393
Number of successful extensions: 6243
Number of sequences better than 10.0: 102
Number of HSP's better than 10.0 without gapping: 5793
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6075
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11603768198
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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