Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmnc10d12
(787 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 218 2e-56
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 218 2e-56
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 218 2e-56
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 218 2e-56
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 218 2e-56
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 218 2e-56
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 218 2e-56
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 210 4e-54
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 210 4e-54
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 210 4e-54
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 210 4e-54
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 203 5e-52
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 203 5e-52
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 188 1e-47
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 188 1e-47
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 188 1e-47
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 188 1e-47
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 188 1e-47
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 168 2e-41
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 168 2e-41
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 168 2e-41
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 168 2e-41
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 168 2e-41
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 168 2e-41
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 168 2e-41
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 168 2e-41
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 167 4e-41
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 165 1e-40
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 163 6e-40
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 162 1e-39
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 160 5e-39
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 142 2e-33
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 142 2e-33
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 142 2e-33
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 142 2e-33
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 142 2e-33
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 142 2e-33
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 67 8e-11
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 67 8e-11
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 45 4e-04
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 44 6e-04
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 43 0.001
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 43 0.001
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 43 0.001
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 43 0.001
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 43 0.001
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 43 0.001
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 43 0.001
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 43 0.001
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 43 0.001
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 43 0.001
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 43 0.001
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 38 0.041
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 38 0.041
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 38 0.041
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 38 0.041
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 38 0.041
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 38 0.041
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 38 0.041
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 38 0.041
AB177847-1|BAD66825.1| 396|Homo sapiens KIAA1149 splice variant... 38 0.041
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 38 0.041
AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinog... 38 0.054
BC015008-1|AAH15008.1| 203|Homo sapiens HAGHL protein protein. 35 0.38
AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein. 33 1.5
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 32 2.7
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 32 2.7
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 218 bits (533), Expect = 2e-56
Identities = 101/209 (48%), Positives = 136/209 (65%), Gaps = 2/209 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G
Sbjct: 198 ILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKG 257
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L + + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 258 SLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGA 317
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P
Sbjct: 318 VPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPP 377
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 378 PSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 218 bits (533), Expect = 2e-56
Identities = 101/209 (48%), Positives = 136/209 (65%), Gaps = 2/209 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G
Sbjct: 198 ILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKG 257
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L + + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 258 SLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGA 317
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P
Sbjct: 318 VPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPP 377
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 378 PSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 218 bits (533), Expect = 2e-56
Identities = 101/209 (48%), Positives = 136/209 (65%), Gaps = 2/209 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G
Sbjct: 198 ILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKG 257
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L + + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 258 SLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGA 317
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P
Sbjct: 318 VPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPP 377
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 378 PSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 218 bits (533), Expect = 2e-56
Identities = 101/209 (48%), Positives = 136/209 (65%), Gaps = 2/209 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G
Sbjct: 198 ILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKG 257
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L + + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 258 SLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGA 317
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P
Sbjct: 318 VPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPP 377
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 378 PSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 218 bits (533), Expect = 2e-56
Identities = 101/209 (48%), Positives = 136/209 (65%), Gaps = 2/209 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G
Sbjct: 198 ILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKG 257
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L + + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 258 SLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGA 317
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P
Sbjct: 318 VPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPP 377
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 378 PSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 218 bits (533), Expect = 2e-56
Identities = 101/209 (48%), Positives = 136/209 (65%), Gaps = 2/209 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G
Sbjct: 198 ILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKG 257
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L + + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 258 SLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGA 317
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P
Sbjct: 318 VPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPP 377
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 378 PSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 218 bits (533), Expect = 2e-56
Identities = 101/209 (48%), Positives = 136/209 (65%), Gaps = 2/209 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILGMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G
Sbjct: 198 ILGMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKG 257
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L + + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 258 SLSYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGA 317
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P
Sbjct: 318 VPLIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPP 377
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P GPLWILGDVFIG+YYT FD N ++GF
Sbjct: 378 PSGPLWILGDVFIGRYYTVFDRDNNRVGF 406
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 210 bits (513), Expect = 4e-54
Identities = 102/204 (50%), Positives = 132/204 (64%), Gaps = 2/204 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP GSDPAHY
Sbjct: 186 ILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIP 245
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ YW+ HM+ V V CA+GC+AI DTGTSLI GP++E+ AL+AA+G
Sbjct: 246 PLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGG 305
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ CS IP LP V+F + G F L +DYV++ + G +CLSGF ALDVP
Sbjct: 306 IPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPP 365
Query: 235 PMGPLWILGDVFIGKYYTEFDAGN 164
P GP WILGDVF+G Y FD G+
Sbjct: 366 PAGPFWILGDVFLGTYVAVFDRGD 389
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 210 bits (513), Expect = 4e-54
Identities = 102/204 (50%), Positives = 132/204 (64%), Gaps = 2/204 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP GSDPAHY
Sbjct: 186 ILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIP 245
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ YW+ HM+ V V CA+GC+AI DTGTSLI GP++E+ AL+AA+G
Sbjct: 246 PLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGG 305
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ CS IP LP V+F + G F L +DYV++ + G +CLSGF ALDVP
Sbjct: 306 IPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPP 365
Query: 235 PMGPLWILGDVFIGKYYTEFDAGN 164
P GP WILGDVF+G Y FD G+
Sbjct: 366 PAGPFWILGDVFLGTYVAVFDRGD 389
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 210 bits (513), Expect = 4e-54
Identities = 102/204 (50%), Positives = 132/204 (64%), Gaps = 2/204 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP GSDPAHY
Sbjct: 186 ILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIP 245
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ YW+ HM+ V V CA+GC+AI DTGTSLI GP++E+ AL+AA+G
Sbjct: 246 PLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGG 305
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ CS IP LP V+F + G F L +DYV++ + G +CLSGF ALDVP
Sbjct: 306 IPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPP 365
Query: 235 PMGPLWILGDVFIGKYYTEFDAGN 164
P GP WILGDVF+G Y FD G+
Sbjct: 366 PAGPFWILGDVFLGTYVAVFDRGD 389
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 210 bits (513), Expect = 4e-54
Identities = 102/204 (50%), Positives = 132/204 (64%), Gaps = 2/204 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP GSDPAHY
Sbjct: 186 ILGLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIP 245
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ YW+ HM+ V V CA+GC+AI DTGTSLI GP++E+ AL+AA+G
Sbjct: 246 PLTFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGG 305
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ CS IP LP V+F + G F L +DYV++ + G +CLSGF ALDVP
Sbjct: 306 IPLLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPP 365
Query: 235 PMGPLWILGDVFIGKYYTEFDAGN 164
P GP WILGDVF+G Y FD G+
Sbjct: 366 PAGPFWILGDVFLGTYVAVFDRGD 389
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 203 bits (496), Expect = 5e-52
Identities = 100/208 (48%), Positives = 131/208 (62%), Gaps = 2/208 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ F ++V+ V P D +V QGL+ +PVFSFY NRDP GSDPAHY
Sbjct: 182 ILGLGFPILSVEGVRPPLDVLVEQGLLDKPVFSFYFNRDPEVADGGELVLGGSDPAHYIP 241
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ YW+ HM+ V V + CAQGC+AI DTGT +I GP++E+ AL+AA+G
Sbjct: 242 PLTFVPVTVPAYWQIHMERVKVGSRLTLCAQGCAAILDTGTPVIVGPTEEIRALHAAIGG 301
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ CS IP LP V+ I G F L DYV++ AQ +CLSGF ALD+
Sbjct: 302 IPLLAGEYIIRCSEIPKLPAVSLLIGGVWFNLTAQDYVIQFAQGDVRLCLSGFRALDIAS 361
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLG 152
P P+WILGDVF+G Y T FD G+ + G
Sbjct: 362 PPVPVWILGDVFLGAYVTVFDRGDMKSG 389
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 203 bits (496), Expect = 5e-52
Identities = 100/208 (48%), Positives = 131/208 (62%), Gaps = 2/208 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ F ++V+ V P D +V QGL+ +PVFSFY NRDP GSDPAHY
Sbjct: 186 ILGLGFPILSVEGVRPPLDVLVEQGLLDKPVFSFYFNRDPEVADGGELVLGGSDPAHYIP 245
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ YW+ HM+ V V + CAQGC+AI DTGT +I GP++E+ AL+AA+G
Sbjct: 246 PLTFVPVTVPAYWQIHMERVKVGSRLTLCAQGCAAILDTGTPVIVGPTEEIRALHAAIGG 305
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y++ CS IP LP V+ I G F L DYV++ AQ +CLSGF ALD+
Sbjct: 306 IPLLAGEYIIRCSEIPKLPAVSLLIGGVWFNLTAQDYVIQFAQGDVRLCLSGFRALDIAS 365
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLG 152
P P+WILGDVF+G Y T FD G+ + G
Sbjct: 366 PPVPVWILGDVFLGAYVTVFDRGDMKSG 393
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 188 bits (459), Expect = 1e-47
Identities = 93/208 (44%), Positives = 130/208 (62%), Gaps = 2/208 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G
Sbjct: 184 ILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSG 243
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ + YW+ +D++ V + FC++GC AI DTGTSLI GPS +++ L A+GA
Sbjct: 244 SLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA 303
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y V+C+ + +P VTFTI G +TL Y L G C SGF LD+
Sbjct: 304 APVD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHP 362
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLG 152
P GPLWILGDVFI ++Y+ FD GN ++G
Sbjct: 363 PAGPLWILGDVFIRQFYSVFDRGNNRVG 390
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 188 bits (459), Expect = 1e-47
Identities = 93/208 (44%), Positives = 130/208 (62%), Gaps = 2/208 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G
Sbjct: 184 ILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSG 243
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ + YW+ +D++ V + FC++GC AI DTGTSLI GPS +++ L A+GA
Sbjct: 244 SLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA 303
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y V+C+ + +P VTFTI G +TL Y L G C SGF LD+
Sbjct: 304 APVD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHP 362
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLG 152
P GPLWILGDVFI ++Y+ FD GN ++G
Sbjct: 363 PAGPLWILGDVFIRQFYSVFDRGNNRVG 390
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 188 bits (459), Expect = 1e-47
Identities = 93/208 (44%), Positives = 130/208 (62%), Gaps = 2/208 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G
Sbjct: 184 ILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSG 243
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ + YW+ +D++ V + FC++GC AI DTGTSLI GPS +++ L A+GA
Sbjct: 244 SLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA 303
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y V+C+ + +P VTFTI G +TL Y L G C SGF LD+
Sbjct: 304 APVD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHP 362
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLG 152
P GPLWILGDVFI ++Y+ FD GN ++G
Sbjct: 363 PAGPLWILGDVFIRQFYSVFDRGNNRVG 390
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 188 bits (459), Expect = 1e-47
Identities = 93/208 (44%), Positives = 130/208 (62%), Gaps = 2/208 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G
Sbjct: 184 ILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSG 243
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ + YW+ +D++ V + FC++GC AI DTGTSLI GPS +++ L A+GA
Sbjct: 244 SLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA 303
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y V+C+ + +P VTFTI G +TL Y L G C SGF LD+
Sbjct: 304 APVD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHP 362
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLG 152
P GPLWILGDVFI ++Y+ FD GN ++G
Sbjct: 363 PAGPLWILGDVFIRQFYSVFDRGNNRVG 390
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 188 bits (459), Expect = 1e-47
Identities = 93/208 (44%), Positives = 130/208 (62%), Gaps = 2/208 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G
Sbjct: 184 ILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSG 243
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ + YW+ +D++ V + FC++GC AI DTGTSLI GPS +++ L A+GA
Sbjct: 244 SLNWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGA 303
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ G+Y V+C+ + +P VTFTI G +TL Y L G C SGF LD+
Sbjct: 304 APVD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHP 362
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLG 152
P GPLWILGDVFI ++Y+ FD GN ++G
Sbjct: 363 PAGPLWILGDVFIRQFYSVFDRGNNRVG 390
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 168 bits (409), Expect = 2e-41
Identities = 82/211 (38%), Positives = 120/211 (56%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHY 599
++GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY
Sbjct: 86 VVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHY 145
Query: 598 RGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAV 422
G+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+
Sbjct: 146 EGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEAL 205
Query: 421 GATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDV 242
GA YVV C+ P LP ++F + G ++TL DY+ + + +C A+D+
Sbjct: 206 GAKEKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYIFQESYSSKKLCTLAIHAMDI 265
Query: 241 PKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P P GP W LG FI K+YTEFD N ++GF
Sbjct: 266 PPPTGPTWALGATFIRKFYTEFDRRNNRIGF 296
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (408), Expect = 2e-41
Identities = 84/211 (39%), Positives = 121/211 (57%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHY 599
++GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY
Sbjct: 193 VVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHY 252
Query: 598 RGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAV 422
G+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+
Sbjct: 253 EGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEAL 312
Query: 421 GATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDV 242
GA F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+
Sbjct: 313 GAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDI 371
Query: 241 PKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P P GP W LG FI K+YTEFD N ++GF
Sbjct: 372 PPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (408), Expect = 2e-41
Identities = 84/211 (39%), Positives = 121/211 (57%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHY 599
++GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY
Sbjct: 193 VVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHY 252
Query: 598 RGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAV 422
G+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+
Sbjct: 253 EGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEAL 312
Query: 421 GATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDV 242
GA F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+
Sbjct: 313 GAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDI 371
Query: 241 PKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P P GP W LG FI K+YTEFD N ++GF
Sbjct: 372 PPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 168 bits (408), Expect = 2e-41
Identities = 84/211 (39%), Positives = 121/211 (57%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHY 599
++GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY
Sbjct: 193 VVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHY 252
Query: 598 RGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAV 422
G+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+
Sbjct: 253 EGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEAL 312
Query: 421 GATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDV 242
GA F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+
Sbjct: 313 GAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDI 371
Query: 241 PKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P P GP W LG FI K+YTEFD N ++GF
Sbjct: 372 PPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (408), Expect = 2e-41
Identities = 84/211 (39%), Positives = 121/211 (57%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHY 599
++GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY
Sbjct: 193 VVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHY 252
Query: 598 RGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAV 422
G+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+
Sbjct: 253 EGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEAL 312
Query: 421 GATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDV 242
GA F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+
Sbjct: 313 GAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDI 371
Query: 241 PKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P P GP W LG FI K+YTEFD N ++GF
Sbjct: 372 PPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (408), Expect = 2e-41
Identities = 84/211 (39%), Positives = 121/211 (57%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHY 599
++GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY
Sbjct: 193 VVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHY 252
Query: 598 RGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAV 422
G+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+
Sbjct: 253 EGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEAL 312
Query: 421 GATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDV 242
GA F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+
Sbjct: 313 GAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDI 371
Query: 241 PKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P P GP W LG FI K+YTEFD N ++GF
Sbjct: 372 PPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (408), Expect = 2e-41
Identities = 84/211 (39%), Positives = 121/211 (57%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHY 599
++GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY
Sbjct: 193 VVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHY 252
Query: 598 RGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAV 422
G+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+
Sbjct: 253 EGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEAL 312
Query: 421 GATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDV 242
GA F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+
Sbjct: 313 GAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDI 371
Query: 241 PKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P P GP W LG FI K+YTEFD N ++GF
Sbjct: 372 PPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (408), Expect = 2e-41
Identities = 84/211 (39%), Positives = 121/211 (57%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHY 599
++GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY
Sbjct: 193 VVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHY 252
Query: 598 RGDLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAV 422
G+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+
Sbjct: 253 EGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEAL 312
Query: 421 GATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDV 242
GA F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+
Sbjct: 313 GAKKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDI 371
Query: 241 PKPMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P P GP W LG FI K+YTEFD N ++GF
Sbjct: 372 PPPTGPTWALGATFIRKFYTEFDRRNNRIGF 402
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 167 bits (406), Expect = 4e-41
Identities = 83/209 (39%), Positives = 121/209 (57%), Gaps = 2/209 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
++GM F A+ VTP+FDN+++QG++ + VFSFY NR+ + GSDP HY G
Sbjct: 193 VVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRN-SQSLGGQIVLGGSDPQHYEG 251
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 252 NFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGA 311
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+P
Sbjct: 312 KKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPP 370
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P GP W LG FI K+YTEFD N ++GF
Sbjct: 371 PTGPTWALGATFIRKFYTEFDRRNNRIGF 399
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 165 bits (402), Expect = 1e-40
Identities = 83/209 (39%), Positives = 121/209 (57%), Gaps = 2/209 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
++GM F A+ VTP+FDN+++QG++ + VFSFY NR+ + GSDP HY G
Sbjct: 193 VVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRN-SQSLGGQIVLGGSDPQHYEG 251
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 252 NFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSCIEKLMEALGA 311
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+P
Sbjct: 312 KKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPP 370
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLGF 149
P GP W LG FI K+YTEFD N ++GF
Sbjct: 371 PTGPTWALGATFIRKFYTEFDRRNNRIGF 399
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 163 bits (396), Expect = 6e-40
Identities = 85/208 (40%), Positives = 123/208 (59%), Gaps = 2/208 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+A+ +I+ TPVFDN+ QGLV Q +FS YL+ D + + D ++Y G
Sbjct: 182 ILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDKSGSVVIFGGI--DSSYYTG 239
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ + YW+ +DS+ +N CA+GC AI DTGTSL+ GP+ + + + +GA
Sbjct: 240 SLNWVPVTVEGYWQITVDSITMNGETIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGA 299
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ + G VV CS I LP + FTI G + + + Y+L+ C+SGF ++VP
Sbjct: 300 SENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNVPT 355
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLG 152
G LWILGDVFI +Y+T FD N Q+G
Sbjct: 356 ESGELWILGDVFIRQYFTVFDRANNQVG 383
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 162 bits (393), Expect = 1e-39
Identities = 84/208 (40%), Positives = 123/208 (59%), Gaps = 2/208 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+A+ +I+ TPVFDN+ QGLV Q +FS YL+ D + + D ++Y G
Sbjct: 182 ILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGI--DSSYYTG 239
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ + YW+ +DS+ +N CA+GC AI DTGTSL+ GP+ + + + +GA
Sbjct: 240 SLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGA 299
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ + G VV CS I LP + FTI G + + + Y+L+ C+SGF +++P
Sbjct: 300 SENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNLPT 355
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLG 152
G LWILGDVFI +Y+T FD N Q+G
Sbjct: 356 ESGELWILGDVFIRQYFTVFDRANNQVG 383
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 160 bits (389), Expect = 5e-39
Identities = 83/208 (39%), Positives = 123/208 (59%), Gaps = 2/208 (0%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+A+ +I+ TPVFDN+ QGLV Q +FS YL+ D + + D ++Y G
Sbjct: 182 ILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGI--DSSYYTG 239
Query: 592 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 416
L VP+ + YW+ +DS+ +N CA+GC AI DTGTSL+ GP+ + + + +GA
Sbjct: 240 SLNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGA 299
Query: 415 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 236
+ + G VV CS I LP + FTI G + + + Y+L+ C+SGF +++P
Sbjct: 300 SENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNLPT 355
Query: 235 PMGPLWILGDVFIGKYYTEFDAGNRQLG 152
G LWILGDVFI +Y+T F+ N Q+G
Sbjct: 356 ESGELWILGDVFIRQYFTVFERANNQVG 383
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 142 bits (343), Expect = 2e-33
Identities = 76/211 (36%), Positives = 117/211 (55%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
I+G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G
Sbjct: 179 IMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTG 237
Query: 592 DLVRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVG 419
+ P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A G
Sbjct: 238 QIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATG 297
Query: 418 ATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVP 239
A +GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 298 AQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLS 353
Query: 238 KPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 149
G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 354 SQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 384
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 142 bits (343), Expect = 2e-33
Identities = 76/211 (36%), Positives = 117/211 (55%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
I+G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G
Sbjct: 179 IMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTG 237
Query: 592 DLVRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVG 419
+ P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A G
Sbjct: 238 QIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATG 297
Query: 418 ATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVP 239
A +GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 298 AQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLS 353
Query: 238 KPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 149
G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 354 SQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 384
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 142 bits (343), Expect = 2e-33
Identities = 76/211 (36%), Positives = 117/211 (55%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
I+G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G
Sbjct: 176 IMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTG 234
Query: 592 DLVRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVG 419
+ P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A G
Sbjct: 235 QIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATG 294
Query: 418 ATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVP 239
A +GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 295 AQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLS 350
Query: 238 KPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 149
G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 351 SQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 381
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 142 bits (343), Expect = 2e-33
Identities = 76/211 (36%), Positives = 117/211 (55%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
I+G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G
Sbjct: 179 IMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTG 237
Query: 592 DLVRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVG 419
+ P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A G
Sbjct: 238 QIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATG 297
Query: 418 ATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVP 239
A +GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 298 AQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLS 353
Query: 238 KPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 149
G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 354 SQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 384
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 142 bits (343), Expect = 2e-33
Identities = 76/211 (36%), Positives = 117/211 (55%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
I+G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G
Sbjct: 179 IMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTG 237
Query: 592 DLVRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVG 419
+ P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A G
Sbjct: 238 QIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATG 297
Query: 418 ATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVP 239
A +GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 298 AQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLS 353
Query: 238 KPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 149
G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 354 SQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 384
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 142 bits (343), Expect = 2e-33
Identities = 76/211 (36%), Positives = 117/211 (55%), Gaps = 4/211 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
I+G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G
Sbjct: 179 IMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTG 237
Query: 592 DLVRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVG 419
+ P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A G
Sbjct: 238 QIYWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATG 297
Query: 418 ATAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVP 239
A +GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 298 AQEDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLS 353
Query: 238 KPMG-PLWILGDVFIGKYYTEFDAGNRQLGF 149
G PLWILGDVF+ YY+ +D GN ++GF
Sbjct: 354 SQNGQPLWILGDVFLRSYYSVYDLGNNRVGF 384
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 66.9 bits (156), Expect = 8e-11
Identities = 32/80 (40%), Positives = 49/80 (61%), Gaps = 1/80 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G
Sbjct: 184 ILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSG 243
Query: 592 DLVRVPLLRDTYWEFHMDSV 533
L VP+ + YW+ +D++
Sbjct: 244 SLNWVPVTKQAYWQIALDNM 263
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 66.9 bits (156), Expect = 8e-11
Identities = 32/80 (40%), Positives = 49/80 (61%), Gaps = 1/80 (1%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRG 593
ILG+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G
Sbjct: 184 ILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSG 243
Query: 592 DLVRVPLLRDTYWEFHMDSV 533
L VP+ + YW+ +D++
Sbjct: 244 SLNWVPVTKQAYWQIALDNM 263
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 44.8 bits (101), Expect = 4e-04
Identities = 38/146 (26%), Positives = 69/146 (47%), Gaps = 14/146 (9%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 196 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 313
Query: 451 KEVEALNAAVGATAIAFGQYVVDCSL 374
K +A+ AV ++ + Q ++ L
Sbjct: 314 KVFDAVVEAVARASLLYIQPMMGAGL 339
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 15/136 (11%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFYLNRDPG------ATTXXXXXXXGS 614
ILG+A++T+A + FD++V Q + VFS + R G T G
Sbjct: 101 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM-RGAGLPVAGSGTNGGSLVLGGI 159
Query: 613 DPAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGP 455
+P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 160 EPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLP 217
Query: 454 SKEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 218 QKVFDAVVEAVARASL 233
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 14/135 (10%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 196 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 313
Query: 451 KEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 314 KVFDAVVEAVARASL 328
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 14/135 (10%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 196 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 313
Query: 451 KEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 314 KVFDAVVEAVARASL 328
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 14/135 (10%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 93 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 152
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 153 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 210
Query: 451 KEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 211 KVFDAVVEAVARASL 225
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 14/135 (10%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 117 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 176
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 177 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 234
Query: 451 KEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 235 KVFDAVVEAVARASL 249
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 14/135 (10%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 196 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 313
Query: 451 KEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 314 KVFDAVVEAVARASL 328
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 14/135 (10%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 196 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 313
Query: 451 KEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 314 KVFDAVVEAVARASL 328
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 14/135 (10%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 196 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 313
Query: 451 KEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 314 KVFDAVVEAVARASL 328
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 14/135 (10%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 196 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 313
Query: 451 KEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 314 KVFDAVVEAVARASL 328
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 14/135 (10%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 196 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 313
Query: 451 KEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 314 KVFDAVVEAVARASL 328
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 14/135 (10%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 196 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 313
Query: 451 KEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 314 KVFDAVVEAVARASL 328
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 42.7 bits (96), Expect = 0.001
Identities = 36/135 (26%), Positives = 64/135 (47%), Gaps = 14/135 (10%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSD 611
ILG+A++T+A + FD++V Q + VFS L T G +
Sbjct: 196 ILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIE 255
Query: 610 PAHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPS 452
P+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P
Sbjct: 256 PSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQ 313
Query: 451 KEVEALNAAVGATAI 407
K +A+ AV ++
Sbjct: 314 KVFDAVVEAVARASL 328
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 37.9 bits (84), Expect = 0.041
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXX 620
ILG+A++ IA D + P FD++V Q V +FS F LN+ A+
Sbjct: 179 ILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG 238
Query: 619 GSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGP 455
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P
Sbjct: 239 GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP 298
Query: 454 SKEVEALNAAVGATA 410
K EA ++ A +
Sbjct: 299 KKVFEAAVKSIKAAS 313
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 37.9 bits (84), Expect = 0.041
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXX 620
ILG+A++ IA D + P FD++V Q V +FS F LN+ A+
Sbjct: 179 ILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG 238
Query: 619 GSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGP 455
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P
Sbjct: 239 GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP 298
Query: 454 SKEVEALNAAVGATA 410
K EA ++ A +
Sbjct: 299 KKVFEAAVKSIKAAS 313
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 37.9 bits (84), Expect = 0.041
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXX 620
ILG+A++ IA D + P FD++V Q V +FS F LN+ A+
Sbjct: 179 ILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG 238
Query: 619 GSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGP 455
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P
Sbjct: 239 GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP 298
Query: 454 SKEVEALNAAVGATA 410
K EA ++ A +
Sbjct: 299 KKVFEAAVKSIKAAS 313
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 37.9 bits (84), Expect = 0.041
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXX 620
ILG+A++ IA D + P FD++V Q V +FS F LN+ A+
Sbjct: 179 ILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG 238
Query: 619 GSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGP 455
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P
Sbjct: 239 GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP 298
Query: 454 SKEVEALNAAVGATA 410
K EA ++ A +
Sbjct: 299 KKVFEAAVKSIKAAS 313
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 37.9 bits (84), Expect = 0.041
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXX 620
ILG+A++ IA D + P FD++V Q V +FS F LN+ A+
Sbjct: 179 ILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG 238
Query: 619 GSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGP 455
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P
Sbjct: 239 GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP 298
Query: 454 SKEVEALNAAVGATA 410
K EA ++ A +
Sbjct: 299 KKVFEAAVKSIKAAS 313
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 37.9 bits (84), Expect = 0.041
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXX 620
ILG+A++ IA D + P FD++V Q V +FS F LN+ A+
Sbjct: 179 ILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG 238
Query: 619 GSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGP 455
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P
Sbjct: 239 GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP 298
Query: 454 SKEVEALNAAVGATA 410
K EA ++ A +
Sbjct: 299 KKVFEAAVKSIKAAS 313
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 37.9 bits (84), Expect = 0.041
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXX 620
ILG+A++ IA D + P FD++V Q V +FS F LN+ A+
Sbjct: 166 ILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG 225
Query: 619 GSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGP 455
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P
Sbjct: 226 GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP 285
Query: 454 SKEVEALNAAVGATA 410
K EA ++ A +
Sbjct: 286 KKVFEAAVKSIKAAS 300
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 37.9 bits (84), Expect = 0.041
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXX 620
ILG+A++ IA D + P FD++V Q V +FS F LN+ A+
Sbjct: 179 ILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG 238
Query: 619 GSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGP 455
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P
Sbjct: 239 GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP 298
Query: 454 SKEVEALNAAVGATA 410
K EA ++ A +
Sbjct: 299 KKVFEAAVKSIKAAS 313
>AB177847-1|BAD66825.1| 396|Homo sapiens KIAA1149 splice variant 1
protein.
Length = 396
Score = 37.9 bits (84), Expect = 0.041
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXX 620
ILG+A++ IA D + P FD++V Q V +FS F LN+ A+
Sbjct: 74 ILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG 133
Query: 619 GSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGP 455
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P
Sbjct: 134 GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP 193
Query: 454 SKEVEALNAAVGATA 410
K EA ++ A +
Sbjct: 194 KKVFEAAVKSIKAAS 208
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 37.9 bits (84), Expect = 0.041
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Frame = -1
Query: 769 ILGMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXX 620
ILG+A++ IA D + P FD++V Q V +FS F LN+ A+
Sbjct: 210 ILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG 269
Query: 619 GSDPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGP 455
G D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P
Sbjct: 270 GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP 329
Query: 454 SKEVEALNAAVGATA 410
K EA ++ A +
Sbjct: 330 KKVFEAAVKSIKAAS 344
>AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 140
Score = 37.5 bits (83), Expect = 0.054
Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Frame = -1
Query: 769 ILGMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPG 650
I+G+A+ ++VD T MV +G L PVFS YL+ G
Sbjct: 100 IMGLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQG 140
>BC015008-1|AAH15008.1| 203|Homo sapiens HAGHL protein protein.
Length = 203
Score = 34.7 bits (76), Expect = 0.38
Identities = 47/132 (35%), Positives = 56/132 (42%), Gaps = 11/132 (8%)
Frame = +2
Query: 137 HGGREPELAVPRVELRVVLADEHVPQDPQR-AHG--LRHVQRHEAGQAHRVPELRHPEHV 307
H PELA R L V+ ADE + +R AHG LR R G+ R P P
Sbjct: 59 HARGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRVSARSREGRGGR-PGSTRPHR- 116
Query: 308 VVALEREVVPGDGKGDSRQVRYEAAVHDVLPEGDGR--GAHRRVEGFHLLGG-----PGD 466
A V G + R H++LP G GR G R V G +GG PG
Sbjct: 117 -SACSSAAVRGHPRALPPDARPHRRPHELLPVG-GRLPGPTRPVLGRRAVGGRLRLVPGG 174
Query: 467 QRRARVGD-GRA 499
QR A V + GRA
Sbjct: 175 QRPADVPEPGRA 186
>AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein.
Length = 559
Score = 32.7 bits (71), Expect = 1.5
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 2/30 (6%)
Frame = -2
Query: 294 WRNSGTRCACPASW--RWTCRSPWALCGSW 211
WR S RC SW W+ R W+ CGSW
Sbjct: 459 WRGSWCRCGS-WSWLGSWSWRGSWSWCGSW 487
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 31.9 bits (69), Expect = 2.7
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 13/122 (10%)
Frame = -1
Query: 736 DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGSDPAHYRGDLVR 581
D + P FD++V Q V +FS F LN+ A+ G D + Y G L
Sbjct: 148 DSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWY 207
Query: 580 VPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSKEVEALNAAVGA 416
P+ R+ Y+E + V +N C + +I D+GT+ + P K EA ++ A
Sbjct: 208 TPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKA 267
Query: 415 TA 410
+
Sbjct: 268 AS 269
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 31.9 bits (69), Expect = 2.7
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 13/122 (10%)
Frame = -1
Query: 736 DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGSDPAHYRGDLVR 581
D + P FD++V Q V +FS F LN+ A+ G D + Y G L
Sbjct: 148 DSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWY 207
Query: 580 VPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSKEVEALNAAVGA 416
P+ R+ Y+E + V +N C + +I D+GT+ + P K EA ++ A
Sbjct: 208 TPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKA 267
Query: 415 TA 410
+
Sbjct: 268 AS 269
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,944,628
Number of Sequences: 237096
Number of extensions: 2317202
Number of successful extensions: 8629
Number of sequences better than 10.0: 67
Number of HSP's better than 10.0 without gapping: 7895
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8517
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9590293096
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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