Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmnc10c10
(795 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide succinyl... 221 2e-57
D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide succinyl... 221 2e-57
BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide S-succ... 221 2e-57
BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide S-succ... 221 2e-57
AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein. 221 2e-57
CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein. 221 3e-57
D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial dihydrolipo... 218 2e-56
S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate dehyd... 198 2e-50
Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 ... 95 3e-19
J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide acetyltr... 95 3e-19
BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide S-acet... 95 3e-19
AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide S-acet... 95 3e-19
Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein. 90 7e-18
U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase co... 90 7e-18
U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl tr... 90 7e-18
AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing compo... 90 7e-18
AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide dehydr... 90 7e-18
BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase ... 90 1e-17
X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein. 80 8e-15
J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched ... 80 8e-15
BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branch... 80 8e-15
BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branch... 80 8e-15
M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylas... 79 2e-14
AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branch... 78 4e-14
X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide S-acetyl... 38 0.032
AY396741-1|AAR91619.1| 2850|Homo sapiens hornerin precursor prot... 34 0.68
AL589986-3|CAH70026.1| 2850|Homo sapiens hornerin protein. 34 0.68
U82939-1|AAC98530.1| 815|Homo sapiens p53 binding protein protein. 31 4.8
BC060884-1|AAH60884.1| 1045|Homo sapiens topoisomerase I binding... 31 4.8
AL353671-4|CAH71253.1| 980|Homo sapiens topoisomerase I binding... 31 4.8
AL353671-3|CAH71254.1| 1045|Homo sapiens topoisomerase I binding... 31 4.8
AF098300-1|AAD23379.1| 1045|Homo sapiens topoisomerase I-binding... 31 4.8
AB045733-1|BAB03715.1| 980|Homo sapiens RING-finger protein pro... 31 4.8
AB045732-1|BAB03714.1| 1045|Homo sapiens RING-finger protein pro... 31 4.8
DQ118293-1|AAZ99029.1| 2391|Homo sapiens filaggrin 2 protein. 31 6.3
AY827490-1|AAX12417.1| 2391|Homo sapiens ifapsoriasin protein. 31 6.3
AL356504-2|CAC13173.2| 2391|Homo sapiens filaggrin 2 protein. 31 6.3
>L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 221 bits (540), Expect = 2e-57
Identities = 104/136 (76%), Positives = 117/136 (86%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVATP+GLVVPVIRNV+ M +ADIE TI L EKAR +L IE+MDGGTFTISNGGVF
Sbjct: 318 SVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVF 377
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
GSL GTPIINPPQSAILGMHGIF+RP+A+ G+V +RPMMY+ALTYDHRLIDGREAV FLR
Sbjct: 378 GSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLR 437
Query: 434 KIKEGVEDPATIVAGL 387
KIK VEDP ++ L
Sbjct: 438 KIKAAVEDPRVLLLDL 453
>D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 221 bits (540), Expect = 2e-57
Identities = 104/136 (76%), Positives = 117/136 (86%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVATP+GLVVPVIRNV+ M +ADIE TI L EKAR +L IE+MDGGTFTISNGGVF
Sbjct: 318 SVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVF 377
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
GSL GTPIINPPQSAILGMHGIF+RP+A+ G+V +RPMMY+ALTYDHRLIDGREAV FLR
Sbjct: 378 GSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLR 437
Query: 434 KIKEGVEDPATIVAGL 387
KIK VEDP ++ L
Sbjct: 438 KIKAAVEDPRVLLLDL 453
>BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 221 bits (540), Expect = 2e-57
Identities = 104/136 (76%), Positives = 117/136 (86%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVATP+GLVVPVIRNV+ M +ADIE TI L EKAR +L IE+MDGGTFTISNGGVF
Sbjct: 318 SVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVF 377
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
GSL GTPIINPPQSAILGMHGIF+RP+A+ G+V +RPMMY+ALTYDHRLIDGREAV FLR
Sbjct: 378 GSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLR 437
Query: 434 KIKEGVEDPATIVAGL 387
KIK VEDP ++ L
Sbjct: 438 KIKAAVEDPRVLLLDL 453
>BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 221 bits (540), Expect = 2e-57
Identities = 104/136 (76%), Positives = 117/136 (86%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVATP+GLVVPVIRNV+ M +ADIE TI L EKAR +L IE+MDGGTFTISNGGVF
Sbjct: 318 SVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVF 377
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
GSL GTPIINPPQSAILGMHGIF+RP+A+ G+V +RPMMY+ALTYDHRLIDGREAV FLR
Sbjct: 378 GSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLR 437
Query: 434 KIKEGVEDPATIVAGL 387
KIK VEDP ++ L
Sbjct: 438 KIKAAVEDPRVLLLDL 453
>AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein.
Length = 453
Score = 221 bits (540), Expect = 2e-57
Identities = 104/136 (76%), Positives = 117/136 (86%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVATP+GLVVPVIRNV+ M +ADIE TI L EKAR +L IE+MDGGTFTISNGGVF
Sbjct: 318 SVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVF 377
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
GSL GTPIINPPQSAILGMHGIF+RP+A+ G+V +RPMMY+ALTYDHRLIDGREAV FLR
Sbjct: 378 GSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLR 437
Query: 434 KIKEGVEDPATIVAGL 387
KIK VEDP ++ L
Sbjct: 438 KIKAAVEDPRVLLLDL 453
>CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein.
Length = 453
Score = 221 bits (539), Expect = 3e-57
Identities = 104/136 (76%), Positives = 117/136 (86%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVATP+GLVVPVIRNV+ M +ADIE TI L EKAR +L IE+MDGGTFTISNGGVF
Sbjct: 318 SVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVF 377
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
GSL GTPIINPPQSAILGMHGIF+RP+A+ G+V +RPMMY+ALTYDHRLIDGREAV FLR
Sbjct: 378 GSLFGTPIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLR 437
Query: 434 KIKEGVEDPATIVAGL 387
KIK VEDP ++ L
Sbjct: 438 KIKAAVEDPRVLLFDL 453
>D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial
dihydrolipoamide succinyltransferase protein.
Length = 453
Score = 218 bits (532), Expect = 2e-56
Identities = 103/136 (75%), Positives = 116/136 (85%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVATP+GLVVPVIRNV+ M +ADIE TI L EKAR +L IE+MDGGTFTISNGGVF
Sbjct: 318 SVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVF 377
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
GSL GT IINPPQSAILGMHGIF+RP+A+ G+V +RPMMY+ALTYDHRLIDGREAV FLR
Sbjct: 378 GSLFGTTIINPPQSAILGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLR 437
Query: 434 KIKEGVEDPATIVAGL 387
KIK VEDP ++ L
Sbjct: 438 KIKAAVEDPRVLLLDL 453
>S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate
dehydrogenase complex dihydrolipoyl succinyltransferase
protein.
Length = 451
Score = 198 bits (483), Expect = 2e-50
Identities = 96/136 (70%), Positives = 111/136 (81%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVATP+GLVVPVIRNV+ M YADIE TI L EKAR + IE+MDGGTFTISNGGVF
Sbjct: 317 SVAVATPQGLVVPVIRNVEAMNYADIEQTITELGEKARKNEFAIEDMDGGTFTISNGGVF 376
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
GSL P+ + P SAILGMHGIF++P+A+ G+V +RPMMY+ALTYDHRLIDGREAV FLR
Sbjct: 377 GSLFEHPL-STPLSAILGMHGIFDKPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLR 435
Query: 434 KIKEGVEDPATIVAGL 387
KIK VEDP ++ L
Sbjct: 436 KIKAAVEDPRVLLFDL 451
>Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 to
561) protein.
Length = 615
Score = 95.1 bits (226), Expect = 3e-19
Identities = 51/135 (37%), Positives = 77/135 (57%), Gaps = 2/135 (1%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAV+TP GL+ P++ N I + LA KAR GKL E GGTFTISN G+F
Sbjct: 480 SVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMF 539
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQ--VVIRPMMYIALTYDHRLIDGREAVLF 441
G + IINPPQ+ IL + ++ + + + + MM + L+ DHR++DG +
Sbjct: 540 GIKNFSAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQW 599
Query: 440 LRKIKEGVEDPATIV 396
L + ++ +E P T++
Sbjct: 600 LAEFRKYLEKPITML 614
>J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide
acetyltransferase protein.
Length = 613
Score = 95.1 bits (226), Expect = 3e-19
Identities = 51/135 (37%), Positives = 77/135 (57%), Gaps = 2/135 (1%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAV+TP GL+ P++ N I + LA KAR GKL E GGTFTISN G+F
Sbjct: 478 SVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMF 537
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQ--VVIRPMMYIALTYDHRLIDGREAVLF 441
G + IINPPQ+ IL + ++ + + + + MM + L+ DHR++DG +
Sbjct: 538 GIKNFSAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQW 597
Query: 440 LRKIKEGVEDPATIV 396
L + ++ +E P T++
Sbjct: 598 LAEFRKYLEKPITML 612
>BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 95.1 bits (226), Expect = 3e-19
Identities = 51/135 (37%), Positives = 77/135 (57%), Gaps = 2/135 (1%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAV+TP GL+ P++ N I + LA KAR GKL E GGTFTISN G+F
Sbjct: 512 SVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMF 571
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQ--VVIRPMMYIALTYDHRLIDGREAVLF 441
G + IINPPQ+ IL + ++ + + + + MM + L+ DHR++DG +
Sbjct: 572 GIKNFSAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQW 631
Query: 440 LRKIKEGVEDPATIV 396
L + ++ +E P T++
Sbjct: 632 LAEFRKYLEKPITML 646
>AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 95.1 bits (226), Expect = 3e-19
Identities = 51/135 (37%), Positives = 77/135 (57%), Gaps = 2/135 (1%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAV+TP GL+ P++ N I + LA KAR GKL E GGTFTISN G+F
Sbjct: 512 SVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMF 571
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIALNGQ--VVIRPMMYIALTYDHRLIDGREAVLF 441
G + IINPPQ+ IL + ++ + + + + MM + L+ DHR++DG +
Sbjct: 572 GIKNFSAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQW 631
Query: 440 LRKIKEGVEDPATIV 396
L + ++ +E P T++
Sbjct: 632 LAEFRKYLEKPITML 646
>Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein.
Length = 501
Score = 90.2 bits (214), Expect = 7e-18
Identities = 52/135 (38%), Positives = 80/135 (59%), Gaps = 6/135 (4%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVAT KGL+ P+I++ +I ++ L++KAR GKL EE GG+F+ISN G+F
Sbjct: 364 SVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMF 423
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIAL------NGQVVIRPMMYIALTYDHRLIDGRE 453
G T +INPPQ+ IL + G F + L N ++ R ++ + ++ D R++D
Sbjct: 424 GIDEFTAVINPPQACILAV-GRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 482
Query: 452 AVLFLRKIKEGVEDP 408
A FL+ K +E+P
Sbjct: 483 ATRFLKSFKANLENP 497
>U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase
complex protein X subunit precursor protein.
Length = 501
Score = 90.2 bits (214), Expect = 7e-18
Identities = 52/135 (38%), Positives = 80/135 (59%), Gaps = 6/135 (4%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVAT KGL+ P+I++ +I ++ L++KAR GKL EE GG+F+ISN G+F
Sbjct: 364 SVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMF 423
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIAL------NGQVVIRPMMYIALTYDHRLIDGRE 453
G T +INPPQ+ IL + G F + L N ++ R ++ + ++ D R++D
Sbjct: 424 GIDEFTAVINPPQACILAV-GRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 482
Query: 452 AVLFLRKIKEGVEDP 408
A FL+ K +E+P
Sbjct: 483 ATRFLKSFKANLENP 497
>U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl
transferase protein.
Length = 375
Score = 90.2 bits (214), Expect = 7e-18
Identities = 52/135 (38%), Positives = 80/135 (59%), Gaps = 6/135 (4%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVAT KGL+ P+I++ +I ++ L++KAR GKL EE GG+F+ISN G+F
Sbjct: 238 SVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMF 297
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIAL------NGQVVIRPMMYIALTYDHRLIDGRE 453
G T +INPPQ+ IL + G F + L N ++ R ++ + ++ D R++D
Sbjct: 298 GIDEFTAVINPPQACILAV-GRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 356
Query: 452 AVLFLRKIKEGVEDP 408
A FL+ K +E+P
Sbjct: 357 ATRFLKSFKANLENP 371
>AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing
component X protein.
Length = 501
Score = 90.2 bits (214), Expect = 7e-18
Identities = 52/135 (38%), Positives = 80/135 (59%), Gaps = 6/135 (4%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVAT KGL+ P+I++ +I ++ L++KAR GKL EE GG+F+ISN G+F
Sbjct: 364 SVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMF 423
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIAL------NGQVVIRPMMYIALTYDHRLIDGRE 453
G T +INPPQ+ IL + G F + L N ++ R ++ + ++ D R++D
Sbjct: 424 GIDEFTAVINPPQACILAV-GRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 482
Query: 452 AVLFLRKIKEGVEDP 408
A FL+ K +E+P
Sbjct: 483 ATRFLKSFKANLENP 497
>AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide
dehydrogenase-binding protein protein.
Length = 501
Score = 90.2 bits (214), Expect = 7e-18
Identities = 52/135 (38%), Positives = 80/135 (59%), Gaps = 6/135 (4%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVAT KGL+ P+I++ +I ++ L++KAR GKL EE GG+F+ISN G+F
Sbjct: 364 SVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMF 423
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIAL------NGQVVIRPMMYIALTYDHRLIDGRE 453
G T +INPPQ+ IL + G F + L N ++ R ++ + ++ D R++D
Sbjct: 424 GIDEFTAVINPPQACILAV-GRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 482
Query: 452 AVLFLRKIKEGVEDP 408
A FL+ K +E+P
Sbjct: 483 ATRFLKSFKANLENP 497
>BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase
complex, component X protein.
Length = 501
Score = 89.8 bits (213), Expect = 1e-17
Identities = 52/135 (38%), Positives = 80/135 (59%), Gaps = 6/135 (4%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVF 615
SVAVAT KGL+ P+I++ +I ++ L++KAR GKL EE GG+F+ISN G+F
Sbjct: 364 SVAVATVKGLLTPIIKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMF 423
Query: 614 GSLMGTPIINPPQSAILGMHGIFERPIAL------NGQVVIRPMMYIALTYDHRLIDGRE 453
G T +INPPQ+ IL + G F + L N ++ R ++ + ++ D R++D
Sbjct: 424 GIDEFTAVINPPQACILAV-GRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDEL 482
Query: 452 AVLFLRKIKEGVEDP 408
A FL+ K +E+P
Sbjct: 483 ATRFLKSFKANLENP 497
>X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein.
Length = 482
Score = 80.2 bits (189), Expect = 8e-15
Identities = 46/136 (33%), Positives = 73/136 (53%), Gaps = 1/136 (0%)
Frame = -2
Query: 791 VAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFG 612
+A+ T +GL+VP ++NVQ + DI + L + G+L+ ++ GGTFT+SN G G
Sbjct: 346 IAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIG 405
Query: 611 SLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
P+I PP+ AI + I P G+V +M ++ + DHR+IDG F
Sbjct: 406 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 465
Query: 434 KIKEGVEDPATIVAGL 387
K +E+PA ++ L
Sbjct: 466 LWKSYLENPAFMLLDL 481
>J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched
chain acyltransferase mRNA, complete cds. ).
Length = 477
Score = 80.2 bits (189), Expect = 8e-15
Identities = 46/136 (33%), Positives = 73/136 (53%), Gaps = 1/136 (0%)
Frame = -2
Query: 791 VAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFG 612
+A+ T +GL+VP ++NVQ + DI + L + G+L+ ++ GGTFT+SN G G
Sbjct: 341 IAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIG 400
Query: 611 SLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
P+I PP+ AI + I P G+V +M ++ + DHR+IDG F
Sbjct: 401 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 460
Query: 434 KIKEGVEDPATIVAGL 387
K +E+PA ++ L
Sbjct: 461 LWKSYLENPAFMLLDL 476
>BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase (E2 component of branched chain ke
protein.
Length = 482
Score = 80.2 bits (189), Expect = 8e-15
Identities = 46/136 (33%), Positives = 73/136 (53%), Gaps = 1/136 (0%)
Frame = -2
Query: 791 VAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFG 612
+A+ T +GL+VP ++NVQ + DI + L + G+L+ ++ GGTFT+SN G G
Sbjct: 346 IAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIG 405
Query: 611 SLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
P+I PP+ AI + I P G+V +M ++ + DHR+IDG F
Sbjct: 406 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 465
Query: 434 KIKEGVEDPATIVAGL 387
K +E+PA ++ L
Sbjct: 466 LWKSYLENPAFMLLDL 481
>BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 80.2 bits (189), Expect = 8e-15
Identities = 46/136 (33%), Positives = 73/136 (53%), Gaps = 1/136 (0%)
Frame = -2
Query: 791 VAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFG 612
+A+ T +GL+VP ++NVQ + DI + L + G+L+ ++ GGTFT+SN G G
Sbjct: 346 IAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIG 405
Query: 611 SLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
P+I PP+ AI + I P G+V +M ++ + DHR+IDG F
Sbjct: 406 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 465
Query: 434 KIKEGVEDPATIVAGL 387
K +E+PA ++ L
Sbjct: 466 LWKSYLENPAFMLLDL 481
>M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylase
protein.
Length = 477
Score = 79.0 bits (186), Expect = 2e-14
Identities = 45/136 (33%), Positives = 73/136 (53%), Gaps = 1/136 (0%)
Frame = -2
Query: 791 VAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFG 612
+A+ T +G++VP ++NVQ + DI + L + G+L+ ++ GGTFT+SN G G
Sbjct: 341 IAMDTEQGVIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIG 400
Query: 611 SLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
P+I PP+ AI + I P G+V +M ++ + DHR+IDG F
Sbjct: 401 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 460
Query: 434 KIKEGVEDPATIVAGL 387
K +E+PA ++ L
Sbjct: 461 LWKSYLENPAFMLLDL 476
>AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 77.8 bits (183), Expect = 4e-14
Identities = 45/136 (33%), Positives = 72/136 (52%), Gaps = 1/136 (0%)
Frame = -2
Query: 791 VAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKLTIEEMDGGTFTISNGGVFG 612
+A+ T +GL+VP ++NVQ + DI + L + +L+ ++ GGTFT+SN G G
Sbjct: 346 IAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTFTLSNIGSIG 405
Query: 611 SLMGTPIINPPQSAILGMHGIFERP-IALNGQVVIRPMMYIALTYDHRLIDGREAVLFLR 435
P+I PP+ AI + I P G+V +M ++ + DHR+IDG F
Sbjct: 406 GTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSN 465
Query: 434 KIKEGVEDPATIVAGL 387
K +E+PA ++ L
Sbjct: 466 LWKSYLENPAFMLLDL 481
>X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide
S-acetyltransferase protein.
Length = 220
Score = 38.3 bits (85), Expect = 0.032
Identities = 19/42 (45%), Positives = 24/42 (57%)
Frame = -2
Query: 794 SVAVATPKGLVVPVIRNVQNMTYADIELTIAGLAEKARTGKL 669
SVAV+TP GL+ P++ N I + LA KAR GKL
Sbjct: 176 SVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKL 217
>AY396741-1|AAR91619.1| 2850|Homo sapiens hornerin precursor
protein.
Length = 2850
Score = 33.9 bits (74), Expect = 0.68
Identities = 25/80 (31%), Positives = 34/80 (42%)
Frame = -1
Query: 753 HQKRSEHDLC*YRAHHSWASGKSENR*AHDRRNGRRNVHHQQWRRFRVSDGNANHQSASI 574
H+ SEH Y H S SG S H R+G+ + +Q S H S S
Sbjct: 468 HESSSEHSSG-YTQHGS-GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSR 525
Query: 573 CYTGYARHLRAAHRSERPSR 514
G++RH + +S PSR
Sbjct: 526 QSLGHSRHGSGSGQSPSPSR 545
>AL589986-3|CAH70026.1| 2850|Homo sapiens hornerin protein.
Length = 2850
Score = 33.9 bits (74), Expect = 0.68
Identities = 25/80 (31%), Positives = 34/80 (42%)
Frame = -1
Query: 753 HQKRSEHDLC*YRAHHSWASGKSENR*AHDRRNGRRNVHHQQWRRFRVSDGNANHQSASI 574
H+ SEH Y H S SG S H R+G+ + +Q S H S S
Sbjct: 468 HESSSEHSSG-YTQHGS-GSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSR 525
Query: 573 CYTGYARHLRAAHRSERPSR 514
G++RH + +S PSR
Sbjct: 526 QSLGHSRHGSGSGQSPSPSR 545
>U82939-1|AAC98530.1| 815|Homo sapiens p53 binding protein protein.
Length = 815
Score = 31.1 bits (67), Expect = 4.8
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Frame = -1
Query: 783 RHTERSRRAGHQKRSEHDLC*YRAHHSWASGKSENR*AHD--RRNGRRNVHHQQWRRFRV 610
R RS + Q RS HD +R HH KS+ + + R GRR+ ++ R R
Sbjct: 364 RGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRD---KKRSRTRD 420
Query: 609 SDGNANHQSASICYTGYAR-HLRAAHRSERPSRDQAHDVY 493
S + Q+ S+ +R R++ +R SR + D Y
Sbjct: 421 SSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRY 460
>BC060884-1|AAH60884.1| 1045|Homo sapiens topoisomerase I binding,
arginine/serine-rich protein.
Length = 1045
Score = 31.1 bits (67), Expect = 4.8
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Frame = -1
Query: 783 RHTERSRRAGHQKRSEHDLC*YRAHHSWASGKSENR*AHD--RRNGRRNVHHQQWRRFRV 610
R RS + Q RS HD +R HH KS+ + + R GRR+ ++ R R
Sbjct: 594 RGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRD---KKRSRTRD 650
Query: 609 SDGNANHQSASICYTGYAR-HLRAAHRSERPSRDQAHDVY 493
S + Q+ S+ +R R++ +R SR + D Y
Sbjct: 651 SSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRY 690
>AL353671-4|CAH71253.1| 980|Homo sapiens topoisomerase I binding,
arginine/serine-rich protein.
Length = 980
Score = 31.1 bits (67), Expect = 4.8
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Frame = -1
Query: 783 RHTERSRRAGHQKRSEHDLC*YRAHHSWASGKSENR*AHD--RRNGRRNVHHQQWRRFRV 610
R RS + Q RS HD +R HH KS+ + + R GRR+ ++ R R
Sbjct: 529 RGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRD---KKRSRTRD 585
Query: 609 SDGNANHQSASICYTGYAR-HLRAAHRSERPSRDQAHDVY 493
S + Q+ S+ +R R++ +R SR + D Y
Sbjct: 586 SSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRY 625
>AL353671-3|CAH71254.1| 1045|Homo sapiens topoisomerase I binding,
arginine/serine-rich protein.
Length = 1045
Score = 31.1 bits (67), Expect = 4.8
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Frame = -1
Query: 783 RHTERSRRAGHQKRSEHDLC*YRAHHSWASGKSENR*AHD--RRNGRRNVHHQQWRRFRV 610
R RS + Q RS HD +R HH KS+ + + R GRR+ ++ R R
Sbjct: 594 RGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRD---KKRSRTRD 650
Query: 609 SDGNANHQSASICYTGYAR-HLRAAHRSERPSRDQAHDVY 493
S + Q+ S+ +R R++ +R SR + D Y
Sbjct: 651 SSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRY 690
>AF098300-1|AAD23379.1| 1045|Homo sapiens topoisomerase I-binding RS
protein protein.
Length = 1045
Score = 31.1 bits (67), Expect = 4.8
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Frame = -1
Query: 783 RHTERSRRAGHQKRSEHDLC*YRAHHSWASGKSENR*AHD--RRNGRRNVHHQQWRRFRV 610
R RS + Q RS HD +R HH KS+ + + R GRR+ ++ R R
Sbjct: 594 RGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRD---KKRSRTRD 650
Query: 609 SDGNANHQSASICYTGYAR-HLRAAHRSERPSRDQAHDVY 493
S + Q+ S+ +R R++ +R SR + D Y
Sbjct: 651 SSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRY 690
>AB045733-1|BAB03715.1| 980|Homo sapiens RING-finger protein
protein.
Length = 980
Score = 31.1 bits (67), Expect = 4.8
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Frame = -1
Query: 783 RHTERSRRAGHQKRSEHDLC*YRAHHSWASGKSENR*AHD--RRNGRRNVHHQQWRRFRV 610
R RS + Q RS HD +R HH KS+ + + R GRR+ ++ R R
Sbjct: 529 RGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRD---KKRSRTRD 585
Query: 609 SDGNANHQSASICYTGYAR-HLRAAHRSERPSRDQAHDVY 493
S + Q+ S+ +R R++ +R SR + D Y
Sbjct: 586 SSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRY 625
>AB045732-1|BAB03714.1| 1045|Homo sapiens RING-finger protein
protein.
Length = 1045
Score = 31.1 bits (67), Expect = 4.8
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Frame = -1
Query: 783 RHTERSRRAGHQKRSEHDLC*YRAHHSWASGKSENR*AHD--RRNGRRNVHHQQWRRFRV 610
R RS + Q RS HD +R HH KS+ + + R GRR+ ++ R R
Sbjct: 594 RGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRD---KKRSRTRD 650
Query: 609 SDGNANHQSASICYTGYAR-HLRAAHRSERPSRDQAHDVY 493
S + Q+ S+ +R R++ +R SR + D Y
Sbjct: 651 SSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRY 690
>DQ118293-1|AAZ99029.1| 2391|Homo sapiens filaggrin 2 protein.
Length = 2391
Score = 30.7 bits (66), Expect = 6.3
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Frame = -1
Query: 792 GSGRHTERSRRAGH-QKRSEHDLC*YRAHHSWASGKSENR*AHDRRNGRRNVHHQQWRRF 616
G G+H RS ++ + Q S H +SG++ H +G+ + Q
Sbjct: 832 GFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGS 891
Query: 615 RVSDGNANHQSASICYTGYARHLRAAHRS 529
S G H + S Y+G+ +H +H+S
Sbjct: 892 GQSSGFGQHGTGSGQYSGFGQHESRSHQS 920
>AY827490-1|AAX12417.1| 2391|Homo sapiens ifapsoriasin protein.
Length = 2391
Score = 30.7 bits (66), Expect = 6.3
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Frame = -1
Query: 792 GSGRHTERSRRAGH-QKRSEHDLC*YRAHHSWASGKSENR*AHDRRNGRRNVHHQQWRRF 616
G G+H RS ++ + Q S H +SG++ H +G+ + Q
Sbjct: 832 GFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGS 891
Query: 615 RVSDGNANHQSASICYTGYARHLRAAHRS 529
S G H + S Y+G+ +H +H+S
Sbjct: 892 GQSSGFGQHGTGSGQYSGFGQHESRSHQS 920
>AL356504-2|CAC13173.2| 2391|Homo sapiens filaggrin 2 protein.
Length = 2391
Score = 30.7 bits (66), Expect = 6.3
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Frame = -1
Query: 792 GSGRHTERSRRAGH-QKRSEHDLC*YRAHHSWASGKSENR*AHDRRNGRRNVHHQQWRRF 616
G G+H RS ++ + Q S H +SG++ H +G+ + Q
Sbjct: 832 GFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGS 891
Query: 615 RVSDGNANHQSASICYTGYARHLRAAHRS 529
S G H + S Y+G+ +H +H+S
Sbjct: 892 GQSSGFGQHGTGSGQYSGFGQHESRSHQS 920
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 96,870,908
Number of Sequences: 237096
Number of extensions: 1941337
Number of successful extensions: 3815
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 3641
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3785
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9757565650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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