Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmmt18k12
(885 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 138 2e-32
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 138 2e-32
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 138 2e-32
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 138 2e-32
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 131 4e-30
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 131 4e-30
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 131 4e-30
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 131 4e-30
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 130 7e-30
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 130 9e-30
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 130 9e-30
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 130 9e-30
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 128 3e-29
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 127 6e-29
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 127 6e-29
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 127 6e-29
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 127 6e-29
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 126 1e-28
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 126 1e-28
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 125 2e-28
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 118 2e-26
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 117 7e-26
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 117 7e-26
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 117 7e-26
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 117 7e-26
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 117 7e-26
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 117 7e-26
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 117 7e-26
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 117 7e-26
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 112 1e-24
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 112 1e-24
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 112 1e-24
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 112 1e-24
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 112 1e-24
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 112 1e-24
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 112 1e-24
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 112 1e-24
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 112 1e-24
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 112 1e-24
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 112 1e-24
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 112 1e-24
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 110 6e-24
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 109 1e-23
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 109 1e-23
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 104 4e-22
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 104 4e-22
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 104 5e-22
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 104 5e-22
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 104 5e-22
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 104 5e-22
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 104 5e-22
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 104 5e-22
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 104 5e-22
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 103 9e-22
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 103 1e-21
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 100 8e-21
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 100 8e-21
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 100 8e-21
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 100 8e-21
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 100 8e-21
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 100 8e-21
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 100 8e-21
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 96 2e-19
BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta... 95 3e-19
BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta... 95 3e-19
AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein. 95 3e-19
AY268355-1|AAP42289.1| 300|Homo sapiens short-chain dehydrogena... 95 3e-19
AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid ... 95 3e-19
AB073347-1|BAD38632.1| 300|Homo sapiens putative protein produc... 95 3e-19
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 94 7e-19
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 94 7e-19
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 94 7e-19
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 93 2e-18
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 92 2e-18
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 91 5e-18
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 91 5e-18
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 91 5e-18
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 91 5e-18
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 91 5e-18
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 91 6e-18
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 91 6e-18
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 89 1e-17
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 89 2e-17
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 89 3e-17
AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 89 3e-17
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 89 3e-17
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 89 3e-17
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 88 5e-17
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 88 5e-17
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 88 5e-17
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 88 5e-17
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 88 5e-17
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 88 5e-17
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 87 6e-17
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 87 6e-17
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 87 8e-17
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 87 8e-17
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 87 8e-17
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 87 8e-17
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 87 1e-16
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 87 1e-16
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 86 1e-16
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 86 1e-16
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 86 2e-16
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 85 4e-16
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 85 4e-16
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 85 4e-16
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 85 4e-16
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 85 4e-16
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 84 6e-16
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 84 6e-16
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 84 6e-16
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 84 6e-16
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 84 6e-16
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 84 6e-16
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 84 6e-16
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 84 6e-16
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 84 6e-16
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 83 1e-15
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 83 1e-15
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 83 1e-15
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 83 1e-15
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 83 1e-15
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 81 7e-15
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 80 1e-14
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 79 2e-14
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 79 2e-14
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 79 2e-14
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 79 2e-14
U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid deh... 78 4e-14
CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein. 78 4e-14
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 78 4e-14
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 78 4e-14
BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta... 78 4e-14
AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta... 78 4e-14
AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta... 78 4e-14
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 77 6e-14
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 77 6e-14
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 77 1e-13
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 77 1e-13
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 76 2e-13
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 76 2e-13
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 75 3e-13
BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta... 75 3e-13
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 75 3e-13
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 75 3e-13
AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 75 5e-13
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 74 6e-13
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 74 8e-13
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 74 8e-13
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 74 8e-13
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 74 8e-13
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 74 8e-13
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 74 8e-13
BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein. 73 1e-12
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 72 3e-12
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 72 3e-12
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 71 6e-12
AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein. 71 6e-12
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 71 7e-12
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 71 7e-12
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 71 7e-12
CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein. 71 7e-12
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 71 7e-12
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 71 7e-12
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 71 7e-12
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 71 7e-12
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 71 7e-12
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 70 1e-11
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 70 1e-11
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 69 3e-11
EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta... 69 3e-11
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 69 3e-11
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 69 3e-11
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 68 4e-11
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 68 5e-11
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 68 5e-11
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 68 5e-11
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 67 7e-11
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 67 9e-11
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 67 9e-11
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 67 9e-11
BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 1... 65 3e-10
AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein. 65 3e-10
AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein. 65 3e-10
AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein. 65 3e-10
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 65 4e-10
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 65 4e-10
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 65 4e-10
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 65 4e-10
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 65 4e-10
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 65 4e-10
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 65 4e-10
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 64 6e-10
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 64 6e-10
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 64 6e-10
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 64 6e-10
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 64 6e-10
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 64 6e-10
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 64 6e-10
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 64 6e-10
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 64 6e-10
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 64 9e-10
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 63 1e-09
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 63 1e-09
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 63 1e-09
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 63 1e-09
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 63 1e-09
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 63 1e-09
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 62 2e-09
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 62 2e-09
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 62 2e-09
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 62 3e-09
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 62 3e-09
M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase pro... 61 5e-09
BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase (... 61 5e-09
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 60 8e-09
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 60 8e-09
AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase (... 60 8e-09
M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein. 60 1e-08
J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein. 60 1e-08
EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1 pr... 60 1e-08
CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein. 60 1e-08
CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase... 60 1e-08
BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase... 60 1e-08
BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1 pr... 60 1e-08
BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein. 60 1e-08
BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1 pr... 60 1e-08
BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1 pr... 60 1e-08
AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein. 60 1e-08
AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase (NAP... 60 1e-08
AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1 pr... 60 1e-08
AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein. 60 1e-08
AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1 pr... 60 1e-08
AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase p... 60 1e-08
AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase prot... 60 1e-08
BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase... 60 1e-08
AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase... 60 1e-08
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 58 3e-08
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 58 3e-08
BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein. 58 4e-08
BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein. 58 4e-08
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 56 1e-07
AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase h... 56 1e-07
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 56 2e-07
AY256821-1|AAP94227.1| 526|Homo sapiens WOX8 isoform 8 protein. 55 4e-07
AF325432-1|AAL05449.1| 414|Homo sapiens WW domain-containing ox... 55 4e-07
AF227527-1|AAF82054.1| 414|Homo sapiens FOR II protein protein. 55 4e-07
AF227526-1|AAF82053.1| 363|Homo sapiens FOR I protein protein. 55 4e-07
AF211943-1|AAF27049.1| 414|Homo sapiens WW domain-containing pr... 55 4e-07
BC015582-1|AAH15582.1| 327|Homo sapiens dehydrogenase/reductase... 53 2e-06
EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3 pr... 52 2e-06
CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein. 52 2e-06
BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3 pr... 52 2e-06
AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NAD... 52 2e-06
AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3 pr... 52 2e-06
AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3 va... 52 2e-06
AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3 pr... 52 2e-06
AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbony... 52 2e-06
AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3 pr... 52 2e-06
AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3 pr... 52 2e-06
CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase... 52 3e-06
BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase... 52 3e-06
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 50 8e-06
Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta) ... 48 3e-05
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 47 8e-05
AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase... 46 1e-04
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 46 2e-04
BT007445-1|AAP36113.1| 234|Homo sapiens WW domain containing ox... 46 2e-04
BC003184-1|AAH03184.1| 234|Homo sapiens WWOX protein protein. 46 2e-04
AF395123-1|AAK81727.1| 234|Homo sapiens WWOXdelta6-8 protein. 46 2e-04
AF325429-1|AAL05450.1| 189|Homo sapiens WW domain-containing ox... 46 2e-04
AF227528-1|AAF82055.1| 189|Homo sapiens FOR III protein protein. 46 2e-04
AF187015-1|AAF31694.1| 189|Homo sapiens truncated WW-domain oxi... 46 2e-04
AY444559-1|AAS68535.1| 265|Homo sapiens retinal short chain deh... 45 3e-04
AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reducta... 45 3e-04
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 45 4e-04
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 45 4e-04
BC004331-1|AAH04331.1| 345|Homo sapiens HSDL2 protein protein. 44 6e-04
AL162732-2|CAM17151.1| 345|Homo sapiens hydroxysteroid dehydrog... 44 6e-04
AF162767-1|AAF14537.1| 341|Homo sapiens 17beta-hydroxysteroid d... 44 6e-04
BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta... 41 0.005
BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta... 41 0.005
BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta... 41 0.005
AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein. 41 0.005
AL445197-8|CAI15947.1| 341|Homo sapiens hydroxysteroid (17-beta... 41 0.005
AL445197-7|CAI15946.1| 111|Homo sapiens hydroxysteroid (17-beta... 41 0.005
AL392003-2|CAI13457.1| 341|Homo sapiens hydroxysteroid (17-beta... 41 0.005
AK022929-1|BAB14312.1| 155|Homo sapiens protein ( Homo sapiens ... 41 0.005
AJ249179-1|CAC20418.1| 341|Homo sapiens 17beta-hydroxysteroid d... 41 0.005
AF145023-1|AAP97275.1| 341|Homo sapiens ovarian-specific protei... 41 0.005
AF098786-1|AAF09266.2| 341|Homo sapiens 17 beta-hydroxysteroid ... 41 0.005
BC018336-1|AAH18336.1| 87|Homo sapiens Unknown (protein for MG... 41 0.007
AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid ... 40 0.009
AJ250550-1|CAC88111.1| 341|Homo sapiens 17beta hydroxysteroid d... 40 0.009
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 40 0.012
AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retin... 40 0.016
AF165517-1|AAF86647.1| 223|Homo sapiens 17-beta-hydroxysteroid ... 39 0.021
CR381696-1|CAI95409.1| 245|Homo sapiens dehydrogenase/reductase... 38 0.048
BX649443-1|CAI95430.1| 245|Homo sapiens dehydrogenase/reductase... 38 0.048
BC071987-1|AAH71987.1| 229|Homo sapiens HSD17B7P2 protein protein. 38 0.048
AY829267-1|AAV87307.1| 229|Homo sapiens 17beta-hydroxysteroid d... 38 0.048
BC012536-1|AAH12536.1| 98|Homo sapiens HSD17B12 protein protein. 37 0.085
AY268353-1|AAP42287.1| 199|Homo sapiens short-chain dehydrogena... 37 0.11
AF240697-1|AAF82747.1| 172|Homo sapiens retinol dehydrogenase h... 35 0.45
BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein. 34 0.79
BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein. 34 0.79
AY313896-1|AAP83168.1| 234|Homo sapiens short-chain dehydrogena... 34 0.79
AY268351-1|AAP42285.1| 205|Homo sapiens short-chain dehydrogena... 34 0.79
DQ679794-1|ABG46342.1| 251|Homo sapiens chloride intracellular ... 33 1.0
BC035968-1|AAH35968.1| 251|Homo sapiens chloride intracellular ... 33 1.0
AY032602-1|AAK52083.1| 410|Homo sapiens CLIC5B protein. 33 1.0
AL357057-2|CAI16805.1| 410|Homo sapiens chloride intracellular ... 33 1.0
AL357057-1|CAI16804.1| 251|Homo sapiens chloride intracellular ... 33 1.0
AL050336-3|CAI21031.1| 410|Homo sapiens chloride intracellular ... 33 1.0
AL050336-1|CAI21030.1| 251|Homo sapiens chloride intracellular ... 33 1.0
AK223130-1|BAD96850.1| 251|Homo sapiens chloride intracellular ... 33 1.0
AK222544-1|BAD96264.1| 251|Homo sapiens chloride intracellular ... 33 1.0
AK075163-1|BAC11444.1| 251|Homo sapiens protein ( Homo sapiens ... 33 1.0
AK075144-1|BAC11432.1| 205|Homo sapiens protein ( Homo sapiens ... 33 1.0
AF216941-1|AAF66928.1| 251|Homo sapiens CLIC5 protein. 33 1.0
BC072434-1|AAH72434.1| 152|Homo sapiens HSD11B1L protein protein. 33 1.8
BC053546-1|AAH53546.1| 152|Homo sapiens hydroxysteroid (11-beta... 33 1.8
AY313895-1|AAP83167.1| 181|Homo sapiens short-chain dehydrogena... 33 1.8
AY268354-1|AAP42288.1| 152|Homo sapiens short-chain dehydrogena... 33 1.8
AL445197-6|CAI15944.1| 84|Homo sapiens hydroxysteroid (17-beta... 31 5.6
AF165514-1|AAF86644.1| 111|Homo sapiens 17-beta-hydroxysteroid ... 31 5.6
AF325432-2|AAL05451.1| 213|Homo sapiens aberrant WW domain-cont... 31 7.3
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 138 bits (334), Expect = 2e-32
Identities = 80/250 (32%), Positives = 133/250 (53%), Gaps = 1/250 (0%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVV 648
++GKVV++TG GIGA F A +V+ +++ + E + +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA-------VFI 59
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGPY 471
+ DVT E D+K ++ +TI +F +LD +VNNAG E TS + ++ N+ G Y
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 470 LLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
LT LA PYL K++G+++N+SS+ G + Y +K A+ T+ +AL+ +P G+RV
Sbjct: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N ++PG I T + + + + + + LGR G+ EV + FLAS+ A+
Sbjct: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFC 238
Query: 110 TGVTIPVDGG 81
TG+ + V GG
Sbjct: 239 TGIELLVTGG 248
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 138 bits (334), Expect = 2e-32
Identities = 80/250 (32%), Positives = 133/250 (53%), Gaps = 1/250 (0%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVV 648
++GKVV++TG GIGA F A +V+ +++ + E + +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA-------VFI 59
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGPY 471
+ DVT E D+K ++ +TI +F +LD +VNNAG E TS + ++ N+ G Y
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 470 LLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
LT LA PYL K++G+++N+SS+ G + Y +K A+ T+ +AL+ +P G+RV
Sbjct: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N ++PG I T + + + + + + LGR G+ EV + FLAS+ A+
Sbjct: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFC 238
Query: 110 TGVTIPVDGG 81
TG+ + V GG
Sbjct: 239 TGIELLVTGG 248
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 138 bits (334), Expect = 2e-32
Identities = 80/250 (32%), Positives = 133/250 (53%), Gaps = 1/250 (0%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVV 648
++GKVV++TG GIGA F A +V+ +++ + E + +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA-------VFI 59
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGPY 471
+ DVT E D+K ++ +TI +F +LD +VNNAG E TS + ++ N+ G Y
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 470 LLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
LT LA PYL K++G+++N+SS+ G + Y +K A+ T+ +AL+ +P G+RV
Sbjct: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N ++PG I T + + + + + + LGR G+ EV + FLAS+ A+
Sbjct: 180 NCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFC 238
Query: 110 TGVTIPVDGG 81
TG+ + V GG
Sbjct: 239 TGIELLVTGG 248
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 138 bits (334), Expect = 2e-32
Identities = 80/250 (32%), Positives = 133/250 (53%), Gaps = 1/250 (0%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVV 648
++GKVV++TG GIGA F A +V+ +++ + E + +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGA-------VFI 59
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGPY 471
+ DVT E D+K ++ +TI +F +LD +VNNAG E TS + ++ N+ G Y
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 470 LLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
LT LA PYL K++G+++N+SS+ G + Y +K A+ T+ +AL+ +P G+RV
Sbjct: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N ++PG I T + + + + + + LGR G+ EV + FLAS+ A+
Sbjct: 180 NCISPGNIWTPLWEELAALMPDPRASIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFC 238
Query: 110 TGVTIPVDGG 81
TG+ + V GG
Sbjct: 239 TGIELLVTGG 248
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 131 bits (316), Expect = 4e-30
Identities = 86/274 (31%), Positives = 146/274 (53%), Gaps = 5/274 (1%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECE-HVSPNKLKPL 654
+ G+V ++TG ++GIG + +L +N+V+ +R E L+ + E + ++ P K +
Sbjct: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74
Query: 653 VVV-ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
+ + ++ E ++ N++ T++ F K++ LVNN G E+ S + +V+ TN+ G
Sbjct: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134
Query: 476 P-YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
Y+ + + ++ + GSIVN+ V FP + ++A + T+ +ALE A G
Sbjct: 135 TFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 299 IRVNAVNPGVIL--TGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASD 126
IR+N V PGVI T + GS Q +E +K + R G +EVSSV+ FL S
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAK----RIGVPEEVSSVVCFLLSP 249
Query: 125 SASNITGVTIPVDGGRHAMCPR*GRP*NNNHQKG 24
+AS ITG ++ VDGGR P ++N KG
Sbjct: 250 AASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKG 283
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 131 bits (316), Expect = 4e-30
Identities = 86/274 (31%), Positives = 146/274 (53%), Gaps = 5/274 (1%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECE-HVSPNKLKPL 654
+ G+V ++TG ++GIG + +L +N+V+ +R E L+ + E + ++ P K +
Sbjct: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74
Query: 653 VVV-ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
+ + ++ E ++ N++ T++ F K++ LVNN G E+ S + +V+ TN+ G
Sbjct: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134
Query: 476 P-YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
Y+ + + ++ + GSIVN+ V FP + ++A + T+ +ALE A G
Sbjct: 135 TFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 299 IRVNAVNPGVIL--TGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASD 126
IR+N V PGVI T + GS Q +E +K + R G +EVSSV+ FL S
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAK----RIGVPEEVSSVVCFLLSP 249
Query: 125 SASNITGVTIPVDGGRHAMCPR*GRP*NNNHQKG 24
+AS ITG ++ VDGGR P ++N KG
Sbjct: 250 AASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKG 283
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 131 bits (316), Expect = 4e-30
Identities = 86/274 (31%), Positives = 146/274 (53%), Gaps = 5/274 (1%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECE-HVSPNKLKPL 654
+ G+V ++TG ++GIG + +L +N+V+ +R E L+ + E + ++ P K +
Sbjct: 34 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 93
Query: 653 VVV-ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
+ + ++ E ++ N++ T++ F K++ LVNN G E+ S + +V+ TN+ G
Sbjct: 94 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 153
Query: 476 P-YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
Y+ + + ++ + GSIVN+ V FP + ++A + T+ +ALE A G
Sbjct: 154 TFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 212
Query: 299 IRVNAVNPGVIL--TGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASD 126
IR+N V PGVI T + GS Q +E +K + R G +EVSSV+ FL S
Sbjct: 213 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAK----RIGVPEEVSSVVCFLLSP 268
Query: 125 SASNITGVTIPVDGGRHAMCPR*GRP*NNNHQKG 24
+AS ITG ++ VDGGR P ++N KG
Sbjct: 269 AASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKG 302
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 131 bits (316), Expect = 4e-30
Identities = 86/274 (31%), Positives = 146/274 (53%), Gaps = 5/274 (1%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECE-HVSPNKLKPL 654
+ G+V ++TG ++GIG + +L +N+V+ +R E L+ + E + ++ P K +
Sbjct: 15 LLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74
Query: 653 VVV-ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
+ + ++ E ++ N++ T++ F K++ LVNN G E+ S + +V+ TN+ G
Sbjct: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTG 134
Query: 476 P-YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
Y+ + + ++ + GSIVN+ V FP + ++A + T+ +ALE A G
Sbjct: 135 TFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 299 IRVNAVNPGVIL--TGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASD 126
IR+N V PGVI T + GS Q +E +K + R G +EVSSV+ FL S
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAK----RIGVPEEVSSVVCFLLSP 249
Query: 125 SASNITGVTIPVDGGRHAMCPR*GRP*NNNHQKG 24
+AS ITG ++ VDGGR P ++N KG
Sbjct: 250 AASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKG 283
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 130 bits (314), Expect = 7e-30
Identities = 86/274 (31%), Positives = 145/274 (52%), Gaps = 5/274 (1%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECE-HVSPNKLKPL 654
+ G+V +TG ++GIG + +L +N+V+ +R E L+ + E + ++ P K +
Sbjct: 15 LLQGQVAFVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARV 74
Query: 653 VVV-ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
+ + ++ E ++ N++ T++ F K++ LVNN G E+ S + +V+ TN+ G
Sbjct: 75 IPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLRTNLTG 134
Query: 476 P-YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
Y+ + + ++ + GSIVN+ V FP + ++A + T+ +ALE A G
Sbjct: 135 SFYMCKAVYSSWMKEHGGSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSG 193
Query: 299 IRVNAVNPGVIL--TGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASD 126
IR+N V PGVI T + GS Q +E +K + R G +EVSSV+ FL S
Sbjct: 194 IRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAK----RIGVPEEVSSVVCFLLSP 249
Query: 125 SASNITGVTIPVDGGRHAMCPR*GRP*NNNHQKG 24
+AS ITG ++ VDGGR P ++N KG
Sbjct: 250 AASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKG 283
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 130 bits (313), Expect = 9e-30
Identities = 81/250 (32%), Positives = 133/250 (53%), Gaps = 1/250 (0%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLV 651
+ + +V ++TG++SGIG A A+ A++V+++R ++N+++ A+ + L
Sbjct: 33 VLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEG---LSVAG 89
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILA-AGSIENTSLDQYDSVMNTNVRGP 474
+V V D + ++ K + +D LV +AG+ GS TS +D +++ NV+ P
Sbjct: 90 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSP 149
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
LL PY+ +G+++ VSS+A + Y +SK AL TR +ALELAPK IR
Sbjct: 150 ALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIR 209
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASN 114
VN V PG+I T S E + K H L R GE+++ + +++FL S AS
Sbjct: 210 VNCVVPGIIKTDF----SKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASY 265
Query: 113 ITGVTIPVDG 84
+ G I V G
Sbjct: 266 VNGENIAVAG 275
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 130 bits (313), Expect = 9e-30
Identities = 81/250 (32%), Positives = 133/250 (53%), Gaps = 1/250 (0%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLV 651
+ + +V ++TG++SGIG A A+ A++V+++R ++N+++ A+ + L
Sbjct: 24 VLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEG---LSVAG 80
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILA-AGSIENTSLDQYDSVMNTNVRGP 474
+V V D + ++ K + +D LV +AG+ GS TS +D +++ NV+ P
Sbjct: 81 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSP 140
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
LL PY+ +G+++ VSS+A + Y +SK AL TR +ALELAPK IR
Sbjct: 141 ALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIR 200
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASN 114
VN V PG+I T S E + K H L R GE+++ + +++FL S AS
Sbjct: 201 VNCVVPGIIKTDF----SKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASY 256
Query: 113 ITGVTIPVDG 84
+ G I V G
Sbjct: 257 VNGENIAVAG 266
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 130 bits (313), Expect = 9e-30
Identities = 81/250 (32%), Positives = 133/250 (53%), Gaps = 1/250 (0%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLV 651
+ + +V ++TG++SGIG A A+ A++V+++R ++N+++ A+ + L
Sbjct: 33 VLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEG---LSVAG 89
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILA-AGSIENTSLDQYDSVMNTNVRGP 474
+V V D + ++ K + +D LV +AG+ GS TS +D +++ NV+ P
Sbjct: 90 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSP 149
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
LL PY+ +G+++ VSS+A + Y +SK AL TR +ALELAPK IR
Sbjct: 150 ALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIR 209
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASN 114
VN V PG+I T S E + K H L R GE+++ + +++FL S AS
Sbjct: 210 VNCVVPGIIKTDF----SKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASY 265
Query: 113 ITGVTIPVDG 84
+ G I V G
Sbjct: 266 VNGENIAVAG 275
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 128 bits (309), Expect = 3e-29
Identities = 81/250 (32%), Positives = 132/250 (52%), Gaps = 1/250 (0%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLV 651
+ + +V ++TG++SGIG A A+ A++V+++R ++N+++ A+ + L
Sbjct: 33 VLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEG---LSVAG 89
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILA-AGSIENTSLDQYDSVMNTNVRGP 474
+V V D + ++ K + +D LV +AG+ GS TS +D +++ NV+ P
Sbjct: 90 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSP 149
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
L PY+ +G+++ VSSVA + Y +SK AL TR +ALELAPK IR
Sbjct: 150 APLLSQLLPYMENRRGAVILVSSVAAYNPVVALGVYSVSKTALLGLTRTLALELAPKDIR 209
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASN 114
VN V PG+I T S E + K H L R GE+++ + +++FL S AS
Sbjct: 210 VNCVVPGIIKTDF----SKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASY 265
Query: 113 ITGVTIPVDG 84
+ G I V G
Sbjct: 266 VNGENIAVAG 275
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 127 bits (306), Expect = 6e-29
Identities = 80/250 (32%), Positives = 134/250 (53%), Gaps = 2/250 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+ KV L+T ++ GIG A A+ A++V+++R ++N+++ A + L V
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTV 87
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
V D + ++ + +D+LV+NA + GSI + + + +D ++ NV+ P L
Sbjct: 88 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 147
Query: 467 LTMLATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T P + K G S+V VSS+A P Y +SK AL T+ +A+ELAP+ IRV
Sbjct: 148 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 207
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N + PG+I T M +++ E K T + R GE ++ + +++FL S+ AS I
Sbjct: 208 NCLAPGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYI 263
Query: 110 TGVTIPVDGG 81
TG T+ V GG
Sbjct: 264 TGETVVVGGG 273
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 127 bits (306), Expect = 6e-29
Identities = 80/250 (32%), Positives = 134/250 (53%), Gaps = 2/250 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+ KV L+T ++ GIG A A+ A++V+++R ++N+++ A + L V
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTV 87
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
V D + ++ + +D+LV+NA + GSI + + + +D ++ NV+ P L
Sbjct: 88 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 147
Query: 467 LTMLATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T P + K G S+V VSS+A P Y +SK AL T+ +A+ELAP+ IRV
Sbjct: 148 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 207
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N + PG+I T M +++ E K T + R GE ++ + +++FL S+ AS I
Sbjct: 208 NCLAPGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYI 263
Query: 110 TGVTIPVDGG 81
TG T+ V GG
Sbjct: 264 TGETVVVGGG 273
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 127 bits (306), Expect = 6e-29
Identities = 80/250 (32%), Positives = 134/250 (53%), Gaps = 2/250 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+ KV L+T ++ GIG A A+ A++V+++R ++N+++ A + L V
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTV 87
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
V D + ++ + +D+LV+NA + GSI + + + +D ++ NV+ P L
Sbjct: 88 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 147
Query: 467 LTMLATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T P + K G S+V VSS+A P Y +SK AL T+ +A+ELAP+ IRV
Sbjct: 148 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 207
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N + PG+I T M +++ E K T + R GE ++ + +++FL S+ AS I
Sbjct: 208 NCLAPGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYI 263
Query: 110 TGVTIPVDGG 81
TG T+ V GG
Sbjct: 264 TGETVVVGGG 273
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 127 bits (306), Expect = 6e-29
Identities = 80/250 (32%), Positives = 134/250 (53%), Gaps = 2/250 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+ KV L+T ++ GIG A A+ A++V+++R ++N+++ A + L V
Sbjct: 13 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTV 69
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
V D + ++ + +D+LV+NA + GSI + + + +D ++ NV+ P L
Sbjct: 70 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 129
Query: 467 LTMLATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T P + K G S+V VSS+A P Y +SK AL T+ +A+ELAP+ IRV
Sbjct: 130 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 189
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N + PG+I T M +++ E K T + R GE ++ + +++FL S+ AS I
Sbjct: 190 NCLAPGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYI 245
Query: 110 TGVTIPVDGG 81
TG T+ V GG
Sbjct: 246 TGETVVVGGG 255
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 126 bits (304), Expect = 1e-28
Identities = 80/250 (32%), Positives = 134/250 (53%), Gaps = 2/250 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+ KV L+T ++ GIG A A+ A++V+++R ++N+++ A + L V
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTV 87
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
V D + ++ + +D+LV+NA + GSI + + + +D ++ NV+ P L
Sbjct: 88 CMVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 147
Query: 467 LTMLATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T P + K G S+V VSS+A P Y +SK AL T+ +A+ELAP+ IRV
Sbjct: 148 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 207
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N + PG+I T M +++ E K T + R GE ++ + +++FL S+ AS I
Sbjct: 208 NCLAPGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYI 263
Query: 110 TGVTIPVDGG 81
TG T+ V GG
Sbjct: 264 TGETVVVGGG 273
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 126 bits (304), Expect = 1e-28
Identities = 79/250 (31%), Positives = 134/250 (53%), Gaps = 2/250 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+ KV L+T ++ GIG A A+ A++V+++R ++N+++ A + L V
Sbjct: 13 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTV 69
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
V D + ++ + +D+LV+NA + GS+ + + + +D ++ NV+ P L
Sbjct: 70 CHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPAL 129
Query: 467 LTMLATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T P + K G S+V VSS+A P Y +SK AL T+ +A+ELAP+ IRV
Sbjct: 130 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 189
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N + PG+I T M +++ E K T + R GE ++ + +++FL S+ AS I
Sbjct: 190 NCLAPGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYI 245
Query: 110 TGVTIPVDGG 81
TG T+ V GG
Sbjct: 246 TGETVVVGGG 255
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 125 bits (302), Expect = 2e-28
Identities = 80/250 (32%), Positives = 133/250 (53%), Gaps = 2/250 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+ KV L T ++ GIG A A+ A++V+++R ++N+++ A + L V
Sbjct: 31 ANKVALATASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTV 87
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
V D + ++ + +D+LV+NA + GSI + + + +D ++ NV+ P L
Sbjct: 88 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 147
Query: 467 LTMLATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T P + K G S+V VSS+A P Y +SK AL T+ +A+ELAP+ IRV
Sbjct: 148 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 207
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N + PG+I T M +++ E K T + R GE ++ + +++FL S+ AS I
Sbjct: 208 NCLAPGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYI 263
Query: 110 TGVTIPVDGG 81
TG T+ V GG
Sbjct: 264 TGETVVVGGG 273
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 118 bits (285), Expect = 2e-26
Identities = 77/253 (30%), Positives = 121/253 (47%), Gaps = 2/253 (0%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
+ +G+ VL+TGA GIG T A +V +R + +L+ + EC + P
Sbjct: 3 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP------ 56
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V ++ ++ + +D+LVNNA + + + +D N+R
Sbjct: 57 -----VCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAV 111
Query: 473 YLLTMLATPYLVK--TKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
++ +A L+ G+IVNVSS R+ N YC +K ALD T+ +ALEL P
Sbjct: 112 IQVSQIAARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHK 171
Query: 299 IRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSA 120
IRVNAVNP V++T + + + L + LG+ E + V + I FL SD +
Sbjct: 172 IRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRS 227
Query: 119 SNITGVTIPVDGG 81
TG T+PV+GG
Sbjct: 228 GMTTGSTLPVEGG 240
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 117 bits (281), Expect = 7e-26
Identities = 76/253 (30%), Positives = 120/253 (47%), Gaps = 2/253 (0%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
+ +G+ VL+TGA GIG T A +V +R + +L+ + EC + P
Sbjct: 3 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP------ 56
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V ++ ++ + +D+LVNNA + + + +D N+R
Sbjct: 57 -----VCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAV 111
Query: 473 YLLTMLATPYLVK--TKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
++ + L+ G+IVNVSS R+ N YC +K ALD T+ +ALEL P
Sbjct: 112 IQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHK 171
Query: 299 IRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSA 120
IRVNAVNP V++T + + + L + LG+ E + V + I FL SD +
Sbjct: 172 IRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRS 227
Query: 119 SNITGVTIPVDGG 81
TG T+PV+GG
Sbjct: 228 GMTTGSTLPVEGG 240
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 117 bits (281), Expect = 7e-26
Identities = 76/253 (30%), Positives = 120/253 (47%), Gaps = 2/253 (0%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
+ +G+ VL+TGA GIG T A +V +R + +L+ + EC + P
Sbjct: 2 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP------ 55
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V ++ ++ + +D+LVNNA + + + +D N+R
Sbjct: 56 -----VCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAV 110
Query: 473 YLLTMLATPYLVK--TKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
++ + L+ G+IVNVSS R+ N YC +K ALD T+ +ALEL P
Sbjct: 111 IQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHK 170
Query: 299 IRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSA 120
IRVNAVNP V++T + + + L + LG+ E + V + I FL SD +
Sbjct: 171 IRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRS 226
Query: 119 SNITGVTIPVDGG 81
TG T+PV+GG
Sbjct: 227 GMTTGSTLPVEGG 239
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 117 bits (281), Expect = 7e-26
Identities = 76/253 (30%), Positives = 120/253 (47%), Gaps = 2/253 (0%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
+ +G+ VL+TGA GIG T A +V +R + +L+ + EC + P
Sbjct: 3 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP------ 56
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V ++ ++ + +D+LVNNA + + + +D N+R
Sbjct: 57 -----VCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAV 111
Query: 473 YLLTMLATPYLVK--TKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
++ + L+ G+IVNVSS R+ N YC +K ALD T+ +ALEL P
Sbjct: 112 IQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHK 171
Query: 299 IRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSA 120
IRVNAVNP V++T + + + L + LG+ E + V + I FL SD +
Sbjct: 172 IRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRS 227
Query: 119 SNITGVTIPVDGG 81
TG T+PV+GG
Sbjct: 228 GMTTGSTLPVEGG 240
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 117 bits (281), Expect = 7e-26
Identities = 76/253 (30%), Positives = 120/253 (47%), Gaps = 2/253 (0%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
+ +G+ VL+TGA GIG T A +V +R + +L+ + EC + P
Sbjct: 3 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP------ 56
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V ++ ++ + +D+LVNNA + + + +D N+R
Sbjct: 57 -----VCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAV 111
Query: 473 YLLTMLATPYLVK--TKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
++ + L+ G+IVNVSS R+ N YC +K ALD T+ +ALEL P
Sbjct: 112 IQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHK 171
Query: 299 IRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSA 120
IRVNAVNP V++T + + + L + LG+ E + V + I FL SD +
Sbjct: 172 IRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRS 227
Query: 119 SNITGVTIPVDGG 81
TG T+PV+GG
Sbjct: 228 GMTTGSTLPVEGG 240
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 117 bits (281), Expect = 7e-26
Identities = 76/253 (30%), Positives = 120/253 (47%), Gaps = 2/253 (0%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
+ +G+ VL+TGA GIG T A +V +R + +L+ + EC + P
Sbjct: 3 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP------ 56
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V ++ ++ + +D+LVNNA + + + +D N+R
Sbjct: 57 -----VCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAV 111
Query: 473 YLLTMLATPYLVK--TKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
++ + L+ G+IVNVSS R+ N YC +K ALD T+ +ALEL P
Sbjct: 112 IQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHK 171
Query: 299 IRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSA 120
IRVNAVNP V++T + + + L + LG+ E + V + I FL SD +
Sbjct: 172 IRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRS 227
Query: 119 SNITGVTIPVDGG 81
TG T+PV+GG
Sbjct: 228 GMTTGSTLPVEGG 240
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 117 bits (281), Expect = 7e-26
Identities = 76/253 (30%), Positives = 120/253 (47%), Gaps = 2/253 (0%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
+ +G+ VL+TGA GIG T A +V +R + +L+ + EC + P
Sbjct: 3 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP------ 56
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V ++ ++ + +D+LVNNA + + + +D N+R
Sbjct: 57 -----VCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAV 111
Query: 473 YLLTMLATPYLVK--TKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
++ + L+ G+IVNVSS R+ N YC +K ALD T+ +ALEL P
Sbjct: 112 IQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHK 171
Query: 299 IRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSA 120
IRVNAVNP V++T + + + L + LG+ E + V + I FL SD +
Sbjct: 172 IRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRS 227
Query: 119 SNITGVTIPVDGG 81
TG T+PV+GG
Sbjct: 228 GMTTGSTLPVEGG 240
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 117 bits (281), Expect = 7e-26
Identities = 76/253 (30%), Positives = 120/253 (47%), Gaps = 2/253 (0%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
+ +G+ VL+TGA GIG T A +V +R + +L+ + EC + P
Sbjct: 3 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP------ 56
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V ++ ++ + +D+LVNNA + + + +D N+R
Sbjct: 57 -----VCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAV 111
Query: 473 YLLTMLATPYLVK--TKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
++ + L+ G+IVNVSS R+ N YC +K ALD T+ +ALEL P
Sbjct: 112 IQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHK 171
Query: 299 IRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSA 120
IRVNAVNP V++T + + + L + LG+ E + V + I FL SD +
Sbjct: 172 IRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRS 227
Query: 119 SNITGVTIPVDGG 81
TG T+PV+GG
Sbjct: 228 GMTTGSTLPVEGG 240
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 117 bits (281), Expect = 7e-26
Identities = 76/253 (30%), Positives = 120/253 (47%), Gaps = 2/253 (0%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
+ +G+ VL+TGA GIG T A +V +R + +L+ + EC + P
Sbjct: 3 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP------ 56
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V ++ ++ + +D+LVNNA + + + +D N+R
Sbjct: 57 -----VCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAV 111
Query: 473 YLLTMLATPYLVK--TKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
++ + L+ G+IVNVSS R+ N YC +K ALD T+ +ALEL P
Sbjct: 112 IQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHK 171
Query: 299 IRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSA 120
IRVNAVNP V++T + + + L + LG+ E + V + I FL SD +
Sbjct: 172 IRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRS 227
Query: 119 SNITGVTIPVDGG 81
TG T+PV+GG
Sbjct: 228 GMTTGSTLPVEGG 240
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 112 bits (270), Expect = 1e-24
Identities = 73/191 (38%), Positives = 99/191 (51%), Gaps = 4/191 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKL---KPLVVV 645
VV+ITGA+SG+G E A F A LVL RN LE++ E K+ KP +V
Sbjct: 54 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 113
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D+T I + + F +D+LVNNAGI G+I +T++D VM TN GP L
Sbjct: 114 FDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVAL 173
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
T P ++K + G IV +SS+ G S P AY SK A F C+ E+ I V
Sbjct: 174 TKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVT 233
Query: 287 AVNPGVILTGI 255
++PG I T +
Sbjct: 234 VISPGYIHTNL 244
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 112 bits (270), Expect = 1e-24
Identities = 80/249 (32%), Positives = 126/249 (50%), Gaps = 2/249 (0%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
GKV+++T A+ GIG AL FA+ A ++ T N+ L+ E E + + V
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTR----VL 57
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLT 462
DVT K ID+ N+ +LDVL N AG + G++ + +D MN NVR YL+
Sbjct: 58 DVTK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113
Query: 461 MLATPYLVKTK-GSIVNVSSVA-GLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
P ++ K G+I+N+SSVA ++ N Y +KAA+ T+ VA + +GIR N
Sbjct: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173
Query: 287 AVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNIT 108
V PG + T + ++ E GR +E++ + +LASD ++ +T
Sbjct: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESTYVT 233
Query: 107 GVTIPVDGG 81
G + +DGG
Sbjct: 234 GNPVIIDGG 242
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 112 bits (270), Expect = 1e-24
Identities = 73/191 (38%), Positives = 99/191 (51%), Gaps = 4/191 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKL---KPLVVV 645
VV+ITGA+SG+G E A F A LVL RN LE++ E K+ KP +V
Sbjct: 54 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 113
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D+T I + + F +D+LVNNAGI G+I +T++D VM TN GP L
Sbjct: 114 FDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVAL 173
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
T P ++K + G IV +SS+ G S P AY SK A F C+ E+ I V
Sbjct: 174 TKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVT 233
Query: 287 AVNPGVILTGI 255
++PG I T +
Sbjct: 234 VISPGYIHTNL 244
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 112 bits (270), Expect = 1e-24
Identities = 69/190 (36%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAEC-EHVSPNKLKPLVVVAD 639
VV +TGASSGIG E A +KL +LVL+AR LE++ C E+ + + LV+ D
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 111
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
+T + + +F ++D+LVNN G+ +TSLD Y ++ N G LT
Sbjct: 112 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 171
Query: 458 LATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP-KGIRVNA 285
P++++ K G IV V+S+ G+ S P + YC SK AL F + ELA GI V+
Sbjct: 172 CVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSN 231
Query: 284 VNPGVILTGI 255
+ PG + + I
Sbjct: 232 ICPGPVQSNI 241
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 112 bits (270), Expect = 1e-24
Identities = 73/191 (38%), Positives = 99/191 (51%), Gaps = 4/191 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKL---KPLVVV 645
VV+ITGA+SG+G E A F A LVL RN LE++ E K+ KP +V
Sbjct: 54 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 113
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D+T I + + F +D+LVNNAGI G+I +T++D VM TN GP L
Sbjct: 114 FDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVAL 173
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
T P ++K + G IV +SS+ G S P AY SK A F C+ E+ I V
Sbjct: 174 TKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVT 233
Query: 287 AVNPGVILTGI 255
++PG I T +
Sbjct: 234 VISPGYIHTNL 244
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 112 bits (270), Expect = 1e-24
Identities = 69/190 (36%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAEC-EHVSPNKLKPLVVVAD 639
VV +TGASSGIG E A +KL +LVL+AR LE++ C E+ + + LV+ D
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 111
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
+T + + +F ++D+LVNN G+ +TSLD Y ++ N G LT
Sbjct: 112 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 171
Query: 458 LATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP-KGIRVNA 285
P++++ K G IV V+S+ G+ S P + YC SK AL F + ELA GI V+
Sbjct: 172 CVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSN 231
Query: 284 VNPGVILTGI 255
+ PG + + I
Sbjct: 232 ICPGPVQSNI 241
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 112 bits (270), Expect = 1e-24
Identities = 69/190 (36%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAEC-EHVSPNKLKPLVVVAD 639
VV +TGASSGIG E A +KL +LVL+AR LE++ C E+ + + LV+ D
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 61
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
+T + + +F ++D+LVNN G+ +TSLD Y ++ N G LT
Sbjct: 62 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 121
Query: 458 LATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP-KGIRVNA 285
P++++ K G IV V+S+ G+ S P + YC SK AL F + ELA GI V+
Sbjct: 122 CVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSN 181
Query: 284 VNPGVILTGI 255
+ PG + + I
Sbjct: 182 ICPGPVQSNI 191
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 112 bits (270), Expect = 1e-24
Identities = 73/191 (38%), Positives = 99/191 (51%), Gaps = 4/191 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKL---KPLVVV 645
VV+ITGA+SG+G E A F A LVL RN LE++ E K+ KP +V
Sbjct: 39 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 98
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D+T I + + F +D+LVNNAGI G+I +T++D VM TN GP L
Sbjct: 99 FDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVAL 158
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
T P ++K + G IV +SS+ G S P AY SK A F C+ E+ I V
Sbjct: 159 TKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVT 218
Query: 287 AVNPGVILTGI 255
++PG I T +
Sbjct: 219 VISPGYIHTNL 229
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 112 bits (270), Expect = 1e-24
Identities = 80/249 (32%), Positives = 126/249 (50%), Gaps = 2/249 (0%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
GKV+++T A+ GIG AL FA+ A ++ T N+ L+ E E + + V
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTR----VL 57
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLT 462
DVT K ID+ N+ +LDVL N AG + G++ + +D MN NVR YL+
Sbjct: 58 DVTK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113
Query: 461 MLATPYLVKTK-GSIVNVSSVA-GLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
P ++ K G+I+N+SSVA ++ N Y +KAA+ T+ VA + +GIR N
Sbjct: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173
Query: 287 AVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNIT 108
V PG + T + ++ E GR +E++ + +LASD ++ +T
Sbjct: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233
Query: 107 GVTIPVDGG 81
G + +DGG
Sbjct: 234 GNPVIIDGG 242
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 112 bits (270), Expect = 1e-24
Identities = 73/191 (38%), Positives = 99/191 (51%), Gaps = 4/191 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKL---KPLVVV 645
VV+ITGA+SG+G E A F A LVL RN LE++ E K+ KP +V
Sbjct: 59 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 118
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D+T I + + F +D+LVNNAGI G+I +T++D VM TN GP L
Sbjct: 119 FDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVAL 178
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
T P ++K + G IV +SS+ G S P AY SK A F C+ E+ I V
Sbjct: 179 TKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVT 238
Query: 287 AVNPGVILTGI 255
++PG I T +
Sbjct: 239 VISPGYIHTNL 249
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 112 bits (270), Expect = 1e-24
Identities = 69/190 (36%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAEC-EHVSPNKLKPLVVVAD 639
VV +TGASSGIG E A +KL +LVL+AR LE++ C E+ + + LV+ D
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 111
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
+T + + +F ++D+LVNN G+ +TSLD Y ++ N G LT
Sbjct: 112 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 171
Query: 458 LATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP-KGIRVNA 285
P++++ K G IV V+S+ G+ S P + YC SK AL F + ELA GI V+
Sbjct: 172 CVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSN 231
Query: 284 VNPGVILTGI 255
+ PG + + I
Sbjct: 232 ICPGPVQSNI 241
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 112 bits (270), Expect = 1e-24
Identities = 69/190 (36%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAEC-EHVSPNKLKPLVVVAD 639
VV +TGASSGIG E A +KL +LVL+AR LE++ C E+ + + LV+ D
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 61
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
+T + + +F ++D+LVNN G+ +TSLD Y ++ N G LT
Sbjct: 62 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 121
Query: 458 LATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP-KGIRVNA 285
P++++ K G IV V+S+ G+ S P + YC SK AL F + ELA GI V+
Sbjct: 122 CVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSN 181
Query: 284 VNPGVILTGI 255
+ PG + + I
Sbjct: 182 ICPGPVQSNI 191
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 110 bits (265), Expect = 6e-24
Identities = 79/249 (31%), Positives = 126/249 (50%), Gaps = 2/249 (0%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
GKV+++T A+ GIG AL FA+ A ++ T N+ L+ E E + + V
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTR----VL 57
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLT 462
DVT K ID+ ++ +LDVL N AG + G++ + +D MN NVR YL+
Sbjct: 58 DVTK----KKQIDQFASEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113
Query: 461 MLATPYLVKTK-GSIVNVSSVA-GLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
P ++ K G+I+N+SSVA ++ N Y +KAA+ T+ VA + +GIR N
Sbjct: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCN 173
Query: 287 AVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNIT 108
V PG + T + ++ E GR +E++ + +LASD ++ +T
Sbjct: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233
Query: 107 GVTIPVDGG 81
G + +DGG
Sbjct: 234 GNPVIIDGG 242
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 109 bits (263), Expect = 1e-23
Identities = 64/191 (33%), Positives = 107/191 (56%), Gaps = 1/191 (0%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLV 651
+ + +V ++TG++SGIG A A+ A++V+++R ++N+++ A+ + L
Sbjct: 33 VLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEG---LSVAG 89
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILA-AGSIENTSLDQYDSVMNTNVRGP 474
+V V D + ++ K + +D LV +AG+ GS TS +D +++ NV+ P
Sbjct: 90 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSP 149
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
LL PY+ +G+++ VSS+A + Y +SK AL TR +ALELAPK IR
Sbjct: 150 ALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIR 209
Query: 293 VNAVNPGVILT 261
VN V PG+I T
Sbjct: 210 VNCVVPGIIKT 220
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 109 bits (262), Expect = 1e-23
Identities = 78/249 (31%), Positives = 126/249 (50%), Gaps = 2/249 (0%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
GKV+++T A+ GIG AL FA+ A ++ T N+ L+ E E + + V
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTR----VL 57
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLT 462
DVT K ID+ ++ +LDVL N AG + G++ + +D MN NVR YL+
Sbjct: 58 DVTK----KKQIDQFASEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113
Query: 461 MLATPYLVKTK-GSIVNVSSVA-GLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
P ++ K G+I+N+SSVA ++ N Y +KAA+ T+ +A + +GIR N
Sbjct: 114 KAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSLAADFIQQGIRCN 173
Query: 287 AVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNIT 108
V PG + T + ++ E GR +E++ + +LASD ++ +T
Sbjct: 174 CVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVT 233
Query: 107 GVTIPVDGG 81
G + +DGG
Sbjct: 234 GNPVIIDGG 242
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 104 bits (250), Expect = 4e-22
Identities = 82/247 (33%), Positives = 118/247 (47%), Gaps = 1/247 (0%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
KV + G S GIG A A+ L + ARN E + + + L D
Sbjct: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG------DHLAFSCD 56
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
V E D++N ++ +++ LVN AGI G + T + S ++TN+ G L
Sbjct: 57 VAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116
Query: 458 LATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVNAV 282
A +++ +G SIVNV S+ GL+ Y SK L F+R +A E+A K IRVN V
Sbjct: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176
Query: 281 NPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNITGV 102
PG + T M++ E +L+K LGR GET EV+ + FL + ITG
Sbjct: 177 APGFVHT------DMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLL--ESPYITGH 225
Query: 101 TIPVDGG 81
+ VDGG
Sbjct: 226 VLVVDGG 232
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 104 bits (250), Expect = 4e-22
Identities = 82/247 (33%), Positives = 118/247 (47%), Gaps = 1/247 (0%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
KV + G S GIG A A+ L + ARN E + + + L D
Sbjct: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG------DHLAFSCD 56
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
V E D++N ++ +++ LVN AGI G + T + S ++TN+ G L
Sbjct: 57 VAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116
Query: 458 LATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVNAV 282
A +++ +G SIVNV S+ GL+ Y SK L F+R +A E+A K IRVN V
Sbjct: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176
Query: 281 NPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNITGV 102
PG + T M++ E +L+K LGR GET EV+ + FL + ITG
Sbjct: 177 APGFVHT------DMTKDLKEEHLKK---NIPLGRFGETIEVAHAVVFLL--ESPYITGH 225
Query: 101 TIPVDGG 81
+ VDGG
Sbjct: 226 VLVVDGG 232
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 104 bits (249), Expect = 5e-22
Identities = 68/193 (35%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG TA +FAKL++ LVL NK LE+ +A+C+ + K V
Sbjct: 35 TGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLG---AKVHTFV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + DI + K + + +LVNNAG++ + T Q + NV +
Sbjct: 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP---KGI 297
T P + K G IV V+S AG S P +LAYC SK A F + + ELA G+
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 296 RVNAVNPGVILTG 258
+ + P + TG
Sbjct: 212 KTTCLCPNFVNTG 224
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 104 bits (249), Expect = 5e-22
Identities = 68/193 (35%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG TA +FAKL++ LVL NK LE+ +A+C+ + K V
Sbjct: 35 TGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLG---AKVHTFV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + DI + K + + +LVNNAG++ + T Q + NV +
Sbjct: 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP---KGI 297
T P + K G IV V+S AG S P +LAYC SK A F + + ELA G+
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 296 RVNAVNPGVILTG 258
+ + P + TG
Sbjct: 212 KTTCLCPNFVNTG 224
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 104 bits (249), Expect = 5e-22
Identities = 68/193 (35%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG TA +FAKL++ LVL NK LE+ +A+C+ + K V
Sbjct: 35 TGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLG---AKVHTFV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + DI + K + + +LVNNAG++ + T Q + NV +
Sbjct: 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP---KGI 297
T P + K G IV V+S AG S P +LAYC SK A F + + ELA G+
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 296 RVNAVNPGVILTG 258
+ + P + TG
Sbjct: 212 KTTCLCPNFVNTG 224
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 104 bits (249), Expect = 5e-22
Identities = 68/193 (35%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG TA +FAKL++ LVL NK LE+ +A+C+ + K V
Sbjct: 35 TGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLG---AKVHTFV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + DI + K + + +LVNNAG++ + T Q + NV +
Sbjct: 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP---KGI 297
T P + K G IV V+S AG S P +LAYC SK A F + + ELA G+
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 296 RVNAVNPGVILTG 258
+ + P + TG
Sbjct: 212 KTTCLCPNFVNTG 224
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 104 bits (249), Expect = 5e-22
Identities = 68/193 (35%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG TA +FAKL++ LVL NK LE+ +A+C+ + K V
Sbjct: 35 TGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLG---AKVHTFV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + DI + K + + +LVNNAG++ + T Q + NV +
Sbjct: 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP---KGI 297
T P + K G IV V+S AG S P +LAYC SK A F + + ELA G+
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 296 RVNAVNPGVILTG 258
+ + P + TG
Sbjct: 212 KTTCLCPNFVNTG 224
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 104 bits (249), Expect = 5e-22
Identities = 68/193 (35%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG TA +FAKL++ LVL NK LE+ +A+C+ + K V
Sbjct: 35 TGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLG---AKVHTFV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + DI + K + + +LVNNAG++ + T Q + NV +
Sbjct: 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP---KGI 297
T P + K G IV V+S AG S P +LAYC SK A F + + ELA G+
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 296 RVNAVNPGVILTG 258
+ + P + TG
Sbjct: 212 KTTCLCPNFVNTG 224
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 104 bits (249), Expect = 5e-22
Identities = 68/193 (35%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG TA +FAKL++ LVL NK LE+ +A+C+ + K V
Sbjct: 35 TGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLG---AKVHTFV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + DI + K + + +LVNNAG++ + T Q + NV +
Sbjct: 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP---KGI 297
T P + K G IV V+S AG S P +LAYC SK A F + + ELA G+
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 296 RVNAVNPGVILTG 258
+ + P + TG
Sbjct: 212 KTTCLCPNFVNTG 224
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 103 bits (247), Expect = 9e-22
Identities = 70/201 (34%), Positives = 100/201 (49%), Gaps = 4/201 (1%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG TA +FAKL++ LVL NK LE+ +A+C+ + K V
Sbjct: 35 TGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLG---AKVHTFV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + DI + + + +LVNNAG++ + T Q + NV +
Sbjct: 92 VDCSNREDIYSSAKNCKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP---KGI 297
T P + K G IV V+S AG S P +LAYC SK A F + + ELA G+
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 296 RVNAVNPGVILTGIHLKGSMS 234
+ + P + TG K S S
Sbjct: 212 KTTCLCPNFVNTGFIKKMSTS 232
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 103 bits (246), Expect = 1e-21
Identities = 68/193 (35%), Positives = 97/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G+ VLITGA GIG TA +FAKL++ LVL NK LE+ +A+C+ + K V
Sbjct: 35 TGETVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLG---AKVHTFV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + DI + K + + +LVNNAG++ + T Q + NV +
Sbjct: 92 VDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWT 151
Query: 464 TMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP---KGI 297
T P + K G IV V+S AG S P +LAYC SK A F + + ELA G+
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGV 211
Query: 296 RVNAVNPGVILTG 258
+ + P + TG
Sbjct: 212 KTTCLCPNFVNTG 224
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 100 bits (239), Expect = 8e-21
Identities = 74/252 (29%), Positives = 123/252 (48%), Gaps = 7/252 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLT----ARNKENLEKISAECEHVSPNKLKPLVV 648
+ L+TGA SGIG ++ A A + A +E + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 647 VADVTMESDIKNIIDKTINQFNKL-DVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
ADV+ + ++++ F++ V+V+ AGI + + S D +D V+ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 470 LLTMLATPYLVKT--KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
L+T A LV +GSI+N+SS+ G Y SKA + T+ A EL GI
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 296 RVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSAS 117
R N+V PG I T M+Q+ + ++K +G G+ ++V+ V+ FLAS+ +
Sbjct: 193 RCNSVLPGFIAT------PMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246
Query: 116 NITGVTIPVDGG 81
ITG ++ V GG
Sbjct: 247 YITGTSVEVTGG 258
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 100 bits (239), Expect = 8e-21
Identities = 74/252 (29%), Positives = 123/252 (48%), Gaps = 7/252 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLT----ARNKENLEKISAECEHVSPNKLKPLVV 648
+ L+TGA SGIG ++ A A + A +E + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 647 VADVTMESDIKNIIDKTINQFNKL-DVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
ADV+ + ++++ F++ V+V+ AGI + + S D +D V+ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 470 LLTMLATPYLVKT--KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
L+T A LV +GSI+N+SS+ G Y SKA + T+ A EL GI
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 296 RVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSAS 117
R N+V PG I T M+Q+ + ++K +G G+ ++V+ V+ FLAS+ +
Sbjct: 193 RCNSVLPGFIAT------PMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246
Query: 116 NITGVTIPVDGG 81
ITG ++ V GG
Sbjct: 247 YITGTSVEVTGG 258
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 100 bits (239), Expect = 8e-21
Identities = 74/252 (29%), Positives = 123/252 (48%), Gaps = 7/252 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLT----ARNKENLEKISAECEHVSPNKLKPLVV 648
+ L+TGA SGIG ++ A A + A +E + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 647 VADVTMESDIKNIIDKTINQFNKL-DVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
ADV+ + ++++ F++ V+V+ AGI + + S D +D V+ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 470 LLTMLATPYLVKT--KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
L+T A LV +GSI+N+SS+ G Y SKA + T+ A EL GI
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 296 RVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSAS 117
R N+V PG I T M+Q+ + ++K +G G+ ++V+ V+ FLAS+ +
Sbjct: 193 RCNSVLPGFIAT------PMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246
Query: 116 NITGVTIPVDGG 81
ITG ++ V GG
Sbjct: 247 YITGTSVEVTGG 258
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 100 bits (239), Expect = 8e-21
Identities = 74/252 (29%), Positives = 123/252 (48%), Gaps = 7/252 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLT----ARNKENLEKISAECEHVSPNKLKPLVV 648
+ L+TGA SGIG ++ A A + A +E + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 647 VADVTMESDIKNIIDKTINQFNKL-DVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
ADV+ + ++++ F++ V+V+ AGI + + S D +D V+ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 470 LLTMLATPYLVKT--KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
L+T A LV +GSI+N+SS+ G Y SKA + T+ A EL GI
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 296 RVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSAS 117
R N+V PG I T M+Q+ + ++K +G G+ ++V+ V+ FLAS+ +
Sbjct: 193 RCNSVLPGFIAT------PMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246
Query: 116 NITGVTIPVDGG 81
ITG ++ V GG
Sbjct: 247 YITGTSVEVTGG 258
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 100 bits (239), Expect = 8e-21
Identities = 74/252 (29%), Positives = 123/252 (48%), Gaps = 7/252 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLT----ARNKENLEKISAECEHVSPNKLKPLVV 648
+ L+TGA SGIG ++ A A + A +E + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 647 VADVTMESDIKNIIDKTINQFNKL-DVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
ADV+ + ++++ F++ V+V+ AGI + + S D +D V+ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 470 LLTMLATPYLVKT--KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
L+T A LV +GSI+N+SS+ G Y SKA + T+ A EL GI
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 296 RVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSAS 117
R N+V PG I T M+Q+ + ++K +G G+ ++V+ V+ FLAS+ +
Sbjct: 193 RCNSVLPGFIAT------PMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246
Query: 116 NITGVTIPVDGG 81
ITG ++ V GG
Sbjct: 247 YITGTSVEVTGG 258
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 100 bits (239), Expect = 8e-21
Identities = 74/252 (29%), Positives = 123/252 (48%), Gaps = 7/252 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLT----ARNKENLEKISAECEHVSPNKLKPLVV 648
+ L+TGA SGIG ++ A A + A +E + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 647 VADVTMESDIKNIIDKTINQFNKL-DVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
ADV+ + ++++ F++ V+V+ AGI + + S D +D V+ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 470 LLTMLATPYLVKT--KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
L+T A LV +GSI+N+SS+ G Y SKA + T+ A EL GI
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 296 RVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSAS 117
R N+V PG I T M+Q+ + ++K +G G+ ++V+ V+ FLAS+ +
Sbjct: 193 RCNSVLPGFIAT------PMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246
Query: 116 NITGVTIPVDGG 81
ITG ++ V GG
Sbjct: 247 YITGTSVEVTGG 258
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 100 bits (239), Expect = 8e-21
Identities = 74/252 (29%), Positives = 123/252 (48%), Gaps = 7/252 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLT----ARNKENLEKISAECEHVSPNKLKPLVV 648
+ L+TGA SGIG ++ A A + A +E + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 647 VADVTMESDIKNIIDKTINQFNKL-DVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
ADV+ + ++++ F++ V+V+ AGI + + S D +D V+ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 470 LLTMLATPYLVKT--KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
L+T A LV +GSI+N+SS+ G Y SKA + T+ A EL GI
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 296 RVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSAS 117
R N+V PG I T M+Q+ + ++K +G G+ ++V+ V+ FLAS+ +
Sbjct: 193 RCNSVLPGFIAT------PMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 246
Query: 116 NITGVTIPVDGG 81
ITG ++ V GG
Sbjct: 247 YITGTSVEVTGG 258
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 95.9 bits (228), Expect = 2e-19
Identities = 72/252 (28%), Positives = 122/252 (48%), Gaps = 7/252 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEANLVLT----ARNKENLEKISAECEHVSPNKLKPLVV 648
+ L+TGA SGIG ++ A A + A +E + + P +
Sbjct: 11 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 70
Query: 647 VADVTMESDIKNIIDKTINQFNKL-DVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
ADV+ + ++++ F++ V+V+ AGI + + S D +D V+ N++G +
Sbjct: 71 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSRDDWDKVIAVNLKGTF 130
Query: 470 LLTMLATPYLVKT--KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
L+T A LV +GSI+N+SS+ G Y SKA + T+ A EL GI
Sbjct: 131 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 190
Query: 296 RVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSAS 117
N+V PG I T M+++ + ++K +G G+ ++V+ V+ FLAS+ +
Sbjct: 191 PCNSVLPGFIAT------PMTKKVPKKVVDKITEMIPMGHLGDPEDVADVVAFLASEDSG 244
Query: 116 NITGVTIPVDGG 81
ITG ++ V GG
Sbjct: 245 YITGTSVEVTGG 256
>BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 95.1 bits (226), Expect = 3e-19
Identities = 58/193 (30%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG +T +FAK ++ LVL NK +E+ +AEC + + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + +I +++ + + ++VNNAG + + +T ++ N+ G + +
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 464 TMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALE---LAPKGI 297
T P ++ + G IV V+SV G P ++ YC SK A F R + E L GI
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 296 RVNAVNPGVILTG 258
+ + + P + TG
Sbjct: 212 KTSCLCPVFVNTG 224
>BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 95.1 bits (226), Expect = 3e-19
Identities = 58/193 (30%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG +T +FAK ++ LVL NK +E+ +AEC + + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + +I +++ + + ++VNNAG + + +T ++ N+ G + +
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 464 TMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALE---LAPKGI 297
T P ++ + G IV V+SV G P ++ YC SK A F R + E L GI
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 296 RVNAVNPGVILTG 258
+ + + P + TG
Sbjct: 212 KTSCLCPVFVNTG 224
>AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein.
Length = 300
Score = 95.1 bits (226), Expect = 3e-19
Identities = 58/193 (30%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG +T +FAK ++ LVL NK +E+ +AEC + + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + +I +++ + + ++VNNAG + + +T ++ N+ G + +
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 464 TMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALE---LAPKGI 297
T P ++ + G IV V+SV G P ++ YC SK A F R + E L GI
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 296 RVNAVNPGVILTG 258
+ + + P + TG
Sbjct: 212 KTSCLCPVFVNTG 224
>AY268355-1|AAP42289.1| 300|Homo sapiens short-chain
dehydrogenase/reductase 9 protein.
Length = 300
Score = 95.1 bits (226), Expect = 3e-19
Identities = 58/193 (30%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG +T +FAK ++ LVL NK +E+ +AEC + + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + +I +++ + + ++VNNAG + + +T ++ N+ G + +
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 464 TMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALE---LAPKGI 297
T P ++ + G IV V+SV G P ++ YC SK A F R + E L GI
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 296 RVNAVNPGVILTG 258
+ + + P + TG
Sbjct: 212 KTSCLCPVFVNTG 224
>AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid
dehydrogenase protein.
Length = 300
Score = 95.1 bits (226), Expect = 3e-19
Identities = 58/193 (30%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG +T +FAK ++ LVL NK +E+ +AEC + + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + +I +++ + + ++VNNAG + + +T ++ N+ G + +
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 464 TMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALE---LAPKGI 297
T P ++ + G IV V+SV G P ++ YC SK A F R + E L GI
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 296 RVNAVNPGVILTG 258
+ + + P + TG
Sbjct: 212 KTSCLCPVFVNTG 224
>AB073347-1|BAD38632.1| 300|Homo sapiens putative protein product
of HMFN0376 protein.
Length = 300
Score = 95.1 bits (226), Expect = 3e-19
Identities = 58/193 (30%), Positives = 98/193 (50%), Gaps = 4/193 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA GIG +T +FAK ++ LVL NK +E+ +AEC + + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + +I +++ + + ++VNNAG + + +T ++ N+ G + +
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 464 TMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALE---LAPKGI 297
T P ++ + G IV V+SV G P ++ YC SK A F R + E L GI
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 296 RVNAVNPGVILTG 258
+ + + P + TG
Sbjct: 212 KTSCLCPVFVNTG 224
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 93.9 bits (223), Expect = 7e-19
Identities = 66/190 (34%), Positives = 94/190 (49%), Gaps = 7/190 (3%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEK----ISAECEHVSPNKLKP 657
+G V ITGAS GIG AL AK AN+V+ A+ + K I E + K
Sbjct: 9 AGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKA 68
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
L + DV E I ++K I +F +D+LVNNA ++ + +T + D +MN N RG
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 476 PYLLTMLATPYLVKTK-GSIVNVSSVAGLRS--FPNILAYCISKAALDQFTRCVALELAP 306
YL + PYL K+K I+N+S L F AY I+K + + +A E
Sbjct: 129 TYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEEFKG 188
Query: 305 KGIRVNAVNP 276
+ I VNA+ P
Sbjct: 189 E-IAVNALWP 197
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 93.9 bits (223), Expect = 7e-19
Identities = 66/190 (34%), Positives = 94/190 (49%), Gaps = 7/190 (3%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEK----ISAECEHVSPNKLKP 657
+G V ITGAS GIG AL AK AN+V+ A+ + K I E + K
Sbjct: 9 AGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKA 68
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
L + DV E I ++K I +F +D+LVNNA ++ + +T + D +MN N RG
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 476 PYLLTMLATPYLVKTK-GSIVNVSSVAGLRS--FPNILAYCISKAALDQFTRCVALELAP 306
YL + PYL K+K I+N+S L F AY I+K + + +A E
Sbjct: 129 TYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEEFKG 188
Query: 305 KGIRVNAVNP 276
+ I VNA+ P
Sbjct: 189 E-IAVNALWP 197
>AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 93.9 bits (223), Expect = 7e-19
Identities = 66/190 (34%), Positives = 94/190 (49%), Gaps = 7/190 (3%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEK----ISAECEHVSPNKLKP 657
+G V ITGAS GIG AL AK AN+V+ A+ + K I E + K
Sbjct: 9 AGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKA 68
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
L + DV E I ++K I +F +D+LVNNA ++ + +T + D +MN N RG
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 476 PYLLTMLATPYLVKTK-GSIVNVSSVAGLRS--FPNILAYCISKAALDQFTRCVALELAP 306
YL + PYL K+K I+N+S L F AY I+K + + +A E
Sbjct: 129 TYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEEFKG 188
Query: 305 KGIRVNAVNP 276
+ I VNA+ P
Sbjct: 189 E-IAVNALWP 197
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 92.7 bits (220), Expect = 2e-18
Identities = 77/257 (29%), Positives = 135/257 (52%), Gaps = 13/257 (5%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G+V ++TGAS GIG AL K A + +T R+ + L ++ E + + + P VV
Sbjct: 6 NGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLG-GQCVP--VV 62
Query: 644 ADVTMESDIKNIIDKTIN-QFNKLDVLVNNA--GILAAGSIEN-----TSLDQYDSVMNT 489
D + ES+++++ ++ Q +LDVLVNNA G+ + N T +D + N
Sbjct: 63 CDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNV 122
Query: 488 NVRGPYLLTMLATPYLVKT-KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALEL 312
+RG Y ++ +V +G IV +SS L+ N+L Y + KAA D+ A EL
Sbjct: 123 GLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVL-YGVGKAACDKLAADCAHEL 181
Query: 311 APKGIRVNAVNPGVILTGIHLKGSMSQQE--YEIYLEKCKSTHALGRTGETKEVS-SVIT 141
G+ ++ PG++ T + LK M+++E + L++ KS + + ET E+S +
Sbjct: 182 RRHGVSCVSLWPGIVQTEL-LKEHMAKEEVLQDPVLKQFKSAFS---SAETTELSGKCVV 237
Query: 140 FLASD-SASNITGVTIP 93
LA+D + +++G +P
Sbjct: 238 ALATDPNILSLSGKVLP 254
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 92.3 bits (219), Expect = 2e-18
Identities = 53/142 (37%), Positives = 80/142 (56%), Gaps = 1/142 (0%)
Frame = -2
Query: 503 SVMNTNVRGPYLLTMLATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRC 327
+ ++ NV+ P L+T P + K G S+V VSS+A P Y +SK AL T+
Sbjct: 102 TTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKT 161
Query: 326 VALELAPKGIRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSV 147
+A+ELAP+ IRVN + PG+I T M +++ E K T + R GE ++ + +
Sbjct: 162 LAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGI 217
Query: 146 ITFLASDSASNITGVTIPVDGG 81
++FL S+ AS ITG T+ V GG
Sbjct: 218 VSFLCSEDASYITGETVVVGGG 239
Score = 31.1 bits (67), Expect = 5.6
Identities = 14/44 (31%), Positives = 29/44 (65%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISA 693
+ KV L+T ++ GIG A A+ A++V+++R ++N+++ A
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVA 74
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 91.1 bits (216), Expect = 5e-18
Identities = 58/182 (31%), Positives = 94/182 (51%), Gaps = 1/182 (0%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLV 651
M GK V++TGAS GIG E A AK+ A++V+TAR+KE L+K+ + C + +
Sbjct: 31 MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIA 90
Query: 650 -VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
+ D+T + + + LD+L+ N + ++ + + M N
Sbjct: 91 GTMEDMTF---AEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSY 147
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+LT+ A P L ++ GSIV VSS+AG ++P + AY SK ALD F + E + +
Sbjct: 148 VVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 293 VN 288
V+
Sbjct: 208 VS 209
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 91.1 bits (216), Expect = 5e-18
Identities = 58/182 (31%), Positives = 94/182 (51%), Gaps = 1/182 (0%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLV 651
M GK V++TGAS GIG E A AK+ A++V+TAR+KE L+K+ + C + +
Sbjct: 31 MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIA 90
Query: 650 -VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
+ D+T + + + LD+L+ N + ++ + + M N
Sbjct: 91 GTMEDMTF---AEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSY 147
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+LT+ A P L ++ GSIV VSS+AG ++P + AY SK ALD F + E + +
Sbjct: 148 VVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 293 VN 288
V+
Sbjct: 208 VS 209
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 91.1 bits (216), Expect = 5e-18
Identities = 58/182 (31%), Positives = 94/182 (51%), Gaps = 1/182 (0%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLV 651
M GK V++TGAS GIG E A AK+ A++V+TAR+KE L+K+ + C + +
Sbjct: 31 MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIA 90
Query: 650 -VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
+ D+T + + + LD+L+ N + ++ + + M N
Sbjct: 91 GTMEDMTF---AEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSY 147
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+LT+ A P L ++ GSIV VSS+AG ++P + AY SK ALD F + E + +
Sbjct: 148 VVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 293 VN 288
V+
Sbjct: 208 VS 209
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 91.1 bits (216), Expect = 5e-18
Identities = 58/182 (31%), Positives = 94/182 (51%), Gaps = 1/182 (0%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLV 651
M GK V++TGAS GIG E A AK+ A++V+TAR+KE L+K+ + C + +
Sbjct: 31 MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIA 90
Query: 650 -VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
+ D+T + + + LD+L+ N + ++ + + M N
Sbjct: 91 GTMEDMTF---AEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSY 147
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+LT+ A P L ++ GSIV VSS+AG ++P + AY SK ALD F + E + +
Sbjct: 148 VVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 293 VN 288
V+
Sbjct: 208 VS 209
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 91.1 bits (216), Expect = 5e-18
Identities = 58/182 (31%), Positives = 94/182 (51%), Gaps = 1/182 (0%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLV 651
M GK V++TGAS GIG E A AK+ A++V+TAR+KE L+K+ + C + +
Sbjct: 31 MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIA 90
Query: 650 -VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
+ D+T + + + LD+L+ N + ++ + + M N
Sbjct: 91 GTMEDMTF---AEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSY 147
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+LT+ A P L ++ GSIV VSS+AG ++P + AY SK ALD F + E + +
Sbjct: 148 VVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 293 VN 288
V+
Sbjct: 208 VS 209
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 90.6 bits (215), Expect = 6e-18
Identities = 76/257 (29%), Positives = 134/257 (52%), Gaps = 13/257 (5%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G+V ++TGAS GIG AL K A + +T R+ + L ++ E + + + P VV
Sbjct: 6 NGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLG-GQCVP--VV 62
Query: 644 ADVTMESDIKNIIDKTIN-QFNKLDVLVNNA--GILAAGSIEN-----TSLDQYDSVMNT 489
D + ES+++++ ++ Q +LDVLVNNA G+ + N T +D + N
Sbjct: 63 CDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNV 122
Query: 488 NVRGPYLLTMLATPYLVKT-KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALEL 312
+RG Y ++ +V +G IV +SS L+ N+ Y + KAA D+ A EL
Sbjct: 123 GLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNV-PYGVGKAACDKLAADCAHEL 181
Query: 311 APKGIRVNAVNPGVILTGIHLKGSMSQQE--YEIYLEKCKSTHALGRTGETKEVS-SVIT 141
G+ ++ PG++ T + LK M+++E + L++ KS + + ET E+S +
Sbjct: 182 RRHGVSCVSLWPGIVQTEL-LKEHMAKEEVLQDPVLKQFKSAFS---SAETTELSGKCVV 237
Query: 140 FLASD-SASNITGVTIP 93
LA+D + +++G +P
Sbjct: 238 ALATDPNILSLSGKVLP 254
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 90.6 bits (215), Expect = 6e-18
Identities = 76/257 (29%), Positives = 134/257 (52%), Gaps = 13/257 (5%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G+V ++TGAS GIG AL K A + +T R+ + L ++ E + + + P VV
Sbjct: 6 NGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLG-GQCVP--VV 62
Query: 644 ADVTMESDIKNIIDKTIN-QFNKLDVLVNNA--GILAAGSIEN-----TSLDQYDSVMNT 489
D + ES+++++ ++ Q +LDVLVNNA G+ + N T +D + N
Sbjct: 63 CDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNV 122
Query: 488 NVRGPYLLTMLATPYLVKT-KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALEL 312
+RG Y ++ +V +G IV +SS L+ N+ Y + KAA D+ A EL
Sbjct: 123 GLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNV-PYGVGKAACDKLAADCAHEL 181
Query: 311 APKGIRVNAVNPGVILTGIHLKGSMSQQE--YEIYLEKCKSTHALGRTGETKEVS-SVIT 141
G+ ++ PG++ T + LK M+++E + L++ KS + + ET E+S +
Sbjct: 182 RRHGVSCVSLWPGIVQTEL-LKEHMAKEEVLQDPVLKQFKSAFS---SAETTELSGKCVV 237
Query: 140 FLASD-SASNITGVTIP 93
LA+D + +++G +P
Sbjct: 238 ALATDPNILSLSGKVLP 254
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 89.4 bits (212), Expect = 1e-17
Identities = 55/184 (29%), Positives = 97/184 (52%), Gaps = 2/184 (1%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+ KV L+T ++ GIG A A+ A++V+++R ++N+++ A + L V
Sbjct: 29 TNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTV 85
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
V D + ++ + +D+LV+NA + GS+ + + + +D ++ NV+ P L
Sbjct: 86 CHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPAL 145
Query: 467 LTMLATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T P + K G S+V VSS+A P Y +SK AL +A+ELAP+ IRV
Sbjct: 146 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRV 205
Query: 290 NAVN 279
N ++
Sbjct: 206 NCLH 209
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 89.0 bits (211), Expect = 2e-17
Identities = 75/257 (29%), Positives = 133/257 (51%), Gaps = 13/257 (5%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G+ ++TGAS GIG AL K A + +T R+ + L ++ E + + + P VV
Sbjct: 6 NGQACVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLG-GQCVP--VV 62
Query: 644 ADVTMESDIKNIIDKTIN-QFNKLDVLVNNA--GILAAGSIEN-----TSLDQYDSVMNT 489
D + ES+++++ ++ Q +LDVLVNNA G+ + N T +D + N
Sbjct: 63 CDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNV 122
Query: 488 NVRGPYLLTMLATPYLVKT-KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALEL 312
+RG Y ++ +V +G IV +SS L+ N+ Y + KAA D+ A EL
Sbjct: 123 GLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNV-PYGVGKAACDKLAADCAHEL 181
Query: 311 APKGIRVNAVNPGVILTGIHLKGSMSQQE--YEIYLEKCKSTHALGRTGETKEVS-SVIT 141
G+ ++ PG++ T + LK M+++E + L++ KS + + ET E+S +
Sbjct: 182 RRHGVSCVSLWPGIVQTEL-LKEHMAKEEVLQDPVLKQFKSAFS---SAETTELSGKCVV 237
Query: 140 FLASD-SASNITGVTIP 93
LA+D + +++G +P
Sbjct: 238 ALATDPNILSLSGKVLP 254
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 88.6 bits (210), Expect = 3e-17
Identities = 69/250 (27%), Positives = 123/250 (49%), Gaps = 4/250 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
KV ITG SGIG A F + + V+ +R+ + + + + + PL + D
Sbjct: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM--D 86
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAG---ILAAGSIENTSLDQYDSVMNTNVRGPYL 468
V + +D+ + +F ++D+L+N A + AG++ S + + +VM+ + G +
Sbjct: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL---SFNAFKTVMDIDTSGTFN 143
Query: 467 LT-MLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
++ +L + G IVN+++ G R + +KAA+D TR +A+E P+ IRV
Sbjct: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N++ PG I +G +G + L + L R G E++ + +LAS AS +
Sbjct: 204 NSLAPGPI-SG--TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYV 260
Query: 110 TGVTIPVDGG 81
TG + DGG
Sbjct: 261 TGAVLVADGG 270
>AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 88.6 bits (210), Expect = 3e-17
Identities = 69/250 (27%), Positives = 123/250 (49%), Gaps = 4/250 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
KV ITG SGIG A F + + V+ +R+ + + + + + PL + D
Sbjct: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM--D 86
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAG---ILAAGSIENTSLDQYDSVMNTNVRGPYL 468
V + +D+ + +F ++D+L+N A + AG++ S + + +VM+ + G +
Sbjct: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL---SFNAFKTVMDIDTSGTFN 143
Query: 467 LT-MLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
++ +L + G IVN+++ G R + +KAA+D TR +A+E P+ IRV
Sbjct: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N++ PG I +G +G + L + L R G E++ + +LAS AS +
Sbjct: 204 NSLAPGPI-SG--TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYV 260
Query: 110 TGVTIPVDGG 81
TG + DGG
Sbjct: 261 TGAVLVADGG 270
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 88.6 bits (210), Expect = 3e-17
Identities = 69/250 (27%), Positives = 123/250 (49%), Gaps = 4/250 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
KV ITG SGIG A F + + V+ +R+ + + + + + PL + D
Sbjct: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM--D 86
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAG---ILAAGSIENTSLDQYDSVMNTNVRGPYL 468
V + +D+ + +F ++D+L+N A + AG++ S + + +VM+ + G +
Sbjct: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL---SFNAFKTVMDIDTSGTFN 143
Query: 467 LT-MLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
++ +L + G IVN+++ G R + +KAA+D TR +A+E P+ IRV
Sbjct: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N++ PG I +G +G + L + L R G E++ + +LAS AS +
Sbjct: 204 NSLAPGPI-SG--TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYV 260
Query: 110 TGVTIPVDGG 81
TG + DGG
Sbjct: 261 TGAVLVADGG 270
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 88.6 bits (210), Expect = 3e-17
Identities = 69/250 (27%), Positives = 123/250 (49%), Gaps = 4/250 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
KV ITG SGIG A F + + V+ +R+ + + + + + PL + D
Sbjct: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSM--D 86
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAG---ILAAGSIENTSLDQYDSVMNTNVRGPYL 468
V + +D+ + +F ++D+L+N A + AG++ S + + +VM+ + G +
Sbjct: 87 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL---SFNAFKTVMDIDTSGTFN 143
Query: 467 LT-MLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
++ +L + G IVN+++ G R + +KAA+D TR +A+E P+ IRV
Sbjct: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 203
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N++ PG I +G +G + L + L R G E++ + +LAS AS +
Sbjct: 204 NSLAPGPI-SG--TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYV 260
Query: 110 TGVTIPVDGG 81
TG + DGG
Sbjct: 261 TGAVLVADGG 270
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 87.8 bits (208), Expect = 5e-17
Identities = 62/232 (26%), Positives = 117/232 (50%), Gaps = 4/232 (1%)
Frame = -2
Query: 836 LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKP 657
L+ G+ +++GA+ GIG A + A N++L +RN+E L+ ++ + K++
Sbjct: 62 LIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDI--ADTYKVET 119
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSL--DQYDSVMNTNV 483
++VAD + +I I + + + +LVNN G+ T L D+ ++N N+
Sbjct: 120 DIIVADFSSGREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNI 178
Query: 482 RGPYLLTMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP 306
L+ + P +V + KG+IV +SS + + P + A+ SKA LD F+R + E A
Sbjct: 179 AAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYAS 238
Query: 305 KGIRVNAVNPGVILTGIHLKGS-MSQQEYEIYLEKCKSTHALGRTGETKEVS 153
KGI V ++ P + T + + + + + + K + HA+ G +K +
Sbjct: 239 KGIFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTLGISKRTT 290
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 87.8 bits (208), Expect = 5e-17
Identities = 56/201 (27%), Positives = 94/201 (46%), Gaps = 4/201 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K VL+TG SG G A + K+ E + ++ ++L+ V +
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLR--TVQLN 113
Query: 638 VTMESDIKNIIDKTINQFNKLDV----LVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
V +++ +++ + + LVNNAGI G +E TSL+ Y V N+ G
Sbjct: 114 VCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTV 173
Query: 470 LLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T P + + KG +VN+SS+ G + P YCI+K ++ F+ C+ E+ P G++V
Sbjct: 174 RMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKV 233
Query: 290 NAVNPGVILTGIHLKGSMSQQ 228
+ V PG + L S Q
Sbjct: 234 SVVEPGNFIAATSLYSPESIQ 254
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 87.8 bits (208), Expect = 5e-17
Identities = 56/201 (27%), Positives = 94/201 (46%), Gaps = 4/201 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K VL+TG SG G A + K+ E + ++ ++L+ V +
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLR--TVQLN 113
Query: 638 VTMESDIKNIIDKTINQFNKLDV----LVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
V +++ +++ + + LVNNAGI G +E TSL+ Y V N+ G
Sbjct: 114 VCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTV 173
Query: 470 LLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T P + + KG +VN+SS+ G + P YCI+K ++ F+ C+ E+ P G++V
Sbjct: 174 RMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKV 233
Query: 290 NAVNPGVILTGIHLKGSMSQQ 228
+ V PG + L S Q
Sbjct: 234 SVVEPGNFIAATSLYSPESIQ 254
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 87.8 bits (208), Expect = 5e-17
Identities = 62/232 (26%), Positives = 117/232 (50%), Gaps = 4/232 (1%)
Frame = -2
Query: 836 LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKP 657
L+ G+ +++GA+ GIG A + A N++L +RN+E L+ ++ + K++
Sbjct: 41 LIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDI--ADTYKVET 98
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSL--DQYDSVMNTNV 483
++VAD + +I I + + + +LVNN G+ T L D+ ++N N+
Sbjct: 99 DIIVADFSSGREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNI 157
Query: 482 RGPYLLTMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP 306
L+ + P +V + KG+IV +SS + + P + A+ SKA LD F+R + E A
Sbjct: 158 AAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYAS 217
Query: 305 KGIRVNAVNPGVILTGIHLKGS-MSQQEYEIYLEKCKSTHALGRTGETKEVS 153
KGI V ++ P + T + + + + + + K + HA+ G +K +
Sbjct: 218 KGIFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTLGISKRTT 269
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 87.8 bits (208), Expect = 5e-17
Identities = 62/232 (26%), Positives = 117/232 (50%), Gaps = 4/232 (1%)
Frame = -2
Query: 836 LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKP 657
L+ G+ +++GA+ GIG A + A N++L +RN+E L+ ++ + K++
Sbjct: 62 LIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDI--ADTYKVET 119
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSL--DQYDSVMNTNV 483
++VAD + +I I + + + +LVNN G+ T L D+ ++N N+
Sbjct: 120 DIIVADFSSGREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNI 178
Query: 482 RGPYLLTMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP 306
L+ + P +V + KG+IV +SS + + P + A+ SKA LD F+R + E A
Sbjct: 179 AAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYAS 238
Query: 305 KGIRVNAVNPGVILTGIHLKGS-MSQQEYEIYLEKCKSTHALGRTGETKEVS 153
KGI V ++ P + T + + + + + + K + HA+ G +K +
Sbjct: 239 KGIFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTLGISKRTT 290
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 87.8 bits (208), Expect = 5e-17
Identities = 62/232 (26%), Positives = 117/232 (50%), Gaps = 4/232 (1%)
Frame = -2
Query: 836 LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKP 657
L+ G+ +++GA+ GIG A + A N++L +RN+E L+ ++ + K++
Sbjct: 41 LIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDI--ADTYKVET 98
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSL--DQYDSVMNTNV 483
++VAD + +I I + + + +LVNN G+ T L D+ ++N N+
Sbjct: 99 DIIVADFSSGREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNI 157
Query: 482 RGPYLLTMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP 306
L+ + P +V + KG+IV +SS + + P + A+ SKA LD F+R + E A
Sbjct: 158 AAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYAS 217
Query: 305 KGIRVNAVNPGVILTGIHLKGS-MSQQEYEIYLEKCKSTHALGRTGETKEVS 153
KGI V ++ P + T + + + + + + K + HA+ G +K +
Sbjct: 218 KGIFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTLGISKRTT 269
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 87.4 bits (207), Expect = 6e-17
Identities = 56/201 (27%), Positives = 94/201 (46%), Gaps = 4/201 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K VL+TG SG G A + K+ E + ++ ++L+ V +
Sbjct: 56 KAVLVTGCDSGFGFALAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLR--TVQLN 113
Query: 638 VTMESDIKNIIDKTINQFNKLDV----LVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
V +++ +++ + + LVNNAGI G +E TSL+ Y V N+ G
Sbjct: 114 VCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTV 173
Query: 470 LLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T P + + KG +VN+SS+ G + P YCI+K ++ F+ C+ E+ P G++V
Sbjct: 174 RMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKV 233
Query: 290 NAVNPGVILTGIHLKGSMSQQ 228
+ V PG + L S Q
Sbjct: 234 SVVEPGNFIAATSLYSPESIQ 254
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 87.4 bits (207), Expect = 6e-17
Identities = 66/203 (32%), Positives = 104/203 (51%), Gaps = 16/203 (7%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
GK V++TGA++GIG +TAL+ A+ N++L R ++EK A + + L V
Sbjct: 38 GKTVIVTGANTGIGKQTALELARRGGNIILACR---DMEKCEAAAKDIRGETLNHHVNAR 94
Query: 641 DVTMES--DIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
+ + S I+ K I + ++D+L+NNAG++ T+ D ++ N G +L
Sbjct: 95 HLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCP--HWTTEDGFEMQFGVNHLGHFL 152
Query: 467 LTMLATPYLVKTKGS-IVNVSS---VAG----------LRSFPNILAYCISKAALDQFTR 330
LT L L + S I+N+SS VAG R + AYC SK A+ FT+
Sbjct: 153 LTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTK 212
Query: 329 CVALELAPKGIRVNAVNPGVILT 261
++ L G+ VNA++PGV T
Sbjct: 213 ELSRRLQGSGVTVNALHPGVART 235
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 87.0 bits (206), Expect = 8e-17
Identities = 68/209 (32%), Positives = 100/209 (47%), Gaps = 3/209 (1%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKE-NLEKISAECEHVSPNKLKPLVV 648
+GKV L+TGA+ GIG A A + L N E ++ +A E P K L +
Sbjct: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKT--LFI 61
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV + +++ K ++ F +LD+LVNNAG+ + E T SV + G YL
Sbjct: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSV----ISGTYL 117
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVAL--ELAPKGIR 294
+ G I+N+SS+AGL YC SK + FTR AL L G+R
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLE 207
+NA+ PG + T I L+ ++ Y+E
Sbjct: 178 LNAICPGFVNTAI-LESIEKEENMGQYIE 205
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 87.0 bits (206), Expect = 8e-17
Identities = 68/209 (32%), Positives = 100/209 (47%), Gaps = 3/209 (1%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKE-NLEKISAECEHVSPNKLKPLVV 648
+GKV L+TGA+ GIG A A + L N E ++ +A E P K L +
Sbjct: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKT--LFI 61
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV + +++ K ++ F +LD+LVNNAG+ + E T SV + G YL
Sbjct: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSV----ISGTYL 117
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVAL--ELAPKGIR 294
+ G I+N+SS+AGL YC SK + FTR AL L G+R
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLE 207
+NA+ PG + T I L+ ++ Y+E
Sbjct: 178 LNAICPGFVNTAI-LESIEKEENMGQYIE 205
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 87.0 bits (206), Expect = 8e-17
Identities = 68/209 (32%), Positives = 100/209 (47%), Gaps = 3/209 (1%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKE-NLEKISAECEHVSPNKLKPLVV 648
+GKV L+TGA+ GIG A A + L N E ++ +A E P K L +
Sbjct: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT--LFI 61
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV + +++ K ++ F +LD+LVNNAG+ + E T SV + G YL
Sbjct: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSV----ISGTYL 117
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVAL--ELAPKGIR 294
+ G I+N+SS+AGL YC SK + FTR AL L G+R
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLE 207
+NA+ PG + T I L+ ++ Y+E
Sbjct: 178 LNAICPGFVNTAI-LESIEKEENMGQYIE 205
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 87.0 bits (206), Expect = 8e-17
Identities = 68/209 (32%), Positives = 100/209 (47%), Gaps = 3/209 (1%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKE-NLEKISAECEHVSPNKLKPLVV 648
+GKV L+TGA+ GIG A A + L N E ++ +A E P K L +
Sbjct: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT--LFI 61
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV + +++ K ++ F +LD+LVNNAG+ + E T SV + G YL
Sbjct: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSV----ISGTYL 117
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVAL--ELAPKGIR 294
+ G I+N+SS+AGL YC SK + FTR AL L G+R
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVR 177
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLE 207
+NA+ PG + T I L+ ++ Y+E
Sbjct: 178 LNAICPGFVNTAI-LESIEKEENMGQYIE 205
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 86.6 bits (205), Expect = 1e-16
Identities = 61/232 (26%), Positives = 117/232 (50%), Gaps = 4/232 (1%)
Frame = -2
Query: 836 LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKP 657
L+ G+ +++GA+ GIG A + A N++L +RN+E L+ ++ + K++
Sbjct: 62 LIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDI--ADTYKVET 119
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSL--DQYDSVMNTNV 483
++VAD + +I I + + + +LVNN G+ T L D+ ++N N+
Sbjct: 120 DIIVADFSSGREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNI 178
Query: 482 RGPYLLTMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP 306
L+ + P +V + KG+IV +SS + + P + A+ S+A LD F+R + E A
Sbjct: 179 AAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSRALQYEYAS 238
Query: 305 KGIRVNAVNPGVILTGIHLKGS-MSQQEYEIYLEKCKSTHALGRTGETKEVS 153
KGI V ++ P + T + + + + + + K + HA+ G +K +
Sbjct: 239 KGIFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTLGISKRTT 290
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 86.6 bits (205), Expect = 1e-16
Identities = 61/232 (26%), Positives = 117/232 (50%), Gaps = 4/232 (1%)
Frame = -2
Query: 836 LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKP 657
L+ G+ +++GA+ GIG A + A N++L +RN+E L+ ++ + K++
Sbjct: 62 LIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDI--ADTYKVET 119
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSL--DQYDSVMNTNV 483
++VAD + +I I + + + +LVNN G+ T L D+ ++N N+
Sbjct: 120 DIIVADFSSGREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNI 178
Query: 482 RGPYLLTMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP 306
L+ + P +V + KG+IV +SS + + P + A+ S+A LD F+R + E A
Sbjct: 179 AAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSRALQYEYAS 238
Query: 305 KGIRVNAVNPGVILTGIHLKGS-MSQQEYEIYLEKCKSTHALGRTGETKEVS 153
KGI V ++ P + T + + + + + + K + HA+ G +K +
Sbjct: 239 KGIFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTLGISKRTT 290
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 86.2 bits (204), Expect = 1e-16
Identities = 66/203 (32%), Positives = 104/203 (51%), Gaps = 16/203 (7%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
GK V++TGA++GIG +TAL+ A+ N++L R ++EK A + + L V
Sbjct: 38 GKTVIVTGANTGIGKQTALELARRGGNIILACR---DMEKCEAAAKDIRGETLNHHVNAR 94
Query: 641 DVTMES--DIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
+ + S I+ K I + ++D+L+NNAG++ T+ D ++ N G +L
Sbjct: 95 HLDLASLKSIRVFAAKIIEEEERVDILINNAGVMRCP--HWTTEDGFEMQFGVNHLGHFL 152
Query: 467 LTMLATPYLVKTKGS-IVNVSS---VAG----------LRSFPNILAYCISKAALDQFTR 330
LT L L + S I+N+SS VAG R + AYC SK A+ FT+
Sbjct: 153 LTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTK 212
Query: 329 CVALELAPKGIRVNAVNPGVILT 261
++ L G+ VNA++PGV T
Sbjct: 213 ELSRRLQGSGVTVNALHPGVART 235
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 86.2 bits (204), Expect = 1e-16
Identities = 60/183 (32%), Positives = 87/183 (47%), Gaps = 1/183 (0%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
KV + G S GIG A A+ L + ARN E + + + L D
Sbjct: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGG------DHLAFSCD 56
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
V E D++N ++ +++ LVN AGI G + T + S ++TN+ G L
Sbjct: 57 VAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCK 116
Query: 458 LATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVNAV 282
A +++ +G SIVNV S+ GL+ Y SK L F+R +A E+A K IRVN V
Sbjct: 117 AAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVV 176
Query: 281 NPG 273
PG
Sbjct: 177 APG 179
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 85.8 bits (203), Expect = 2e-16
Identities = 61/232 (26%), Positives = 116/232 (50%), Gaps = 4/232 (1%)
Frame = -2
Query: 836 LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKP 657
L+ G+ +++GA+ GIG A + A N++L +RN+E L+ ++ + K++
Sbjct: 62 LIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDI--ADTYKVET 119
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSL--DQYDSVMNTNV 483
++VAD + +I I + + + +LVNN G+ T L D+ ++N N+
Sbjct: 120 DIIVADFSSGREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNI 178
Query: 482 RGPYLLTMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP 306
L+ + P +V + KG+IV +SS + + P + A+ SKA LD F+R + E A
Sbjct: 179 AAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYAS 238
Query: 305 KGIRVNAVNPGVILTGIHLKGS-MSQQEYEIYLEKCKSTHALGRTGETKEVS 153
KGI V ++ P + + + + + + + K + HA+ G +K +
Sbjct: 239 KGIFVQSLIPFYVAASMTAPSNFLHRCSWLVPSPKVYAHHAVSTLGISKRTT 290
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 84.6 bits (200), Expect = 4e-16
Identities = 63/256 (24%), Positives = 118/256 (46%), Gaps = 3/256 (1%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVV 648
F GKV ITG +G+G + L A V+ +R + L+ + + + NK+ +
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVH--AI 114
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV ++N + + I ++++NNA E S + + ++ + + G
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAF 174
Query: 467 LTMLATPYLVKT-KG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T+ L+K KG + ++++++ ++ +KA ++ ++ +A E G+R
Sbjct: 175 VTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMR 234
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLEK-CKSTHALGRTGETKEVSSVITFLASDSAS 117
N + PG I T KG+ S+ + EK GR G +E++++ FL SD AS
Sbjct: 235 FNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYAS 290
Query: 116 NITGVTIPVDGGRHAM 69
I G I DGG +
Sbjct: 291 WINGAVIKFDGGEEVL 306
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 84.6 bits (200), Expect = 4e-16
Identities = 63/256 (24%), Positives = 118/256 (46%), Gaps = 3/256 (1%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVV 648
F GKV ITG +G+G + L A V+ +R + L+ + + + NK+ +
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVH--AI 114
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV ++N + + I ++++NNA E S + + ++ + + G
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAF 174
Query: 467 LTMLATPYLVKT-KG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T+ L+K KG + ++++++ ++ +KA ++ ++ +A E G+R
Sbjct: 175 VTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMR 234
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLEK-CKSTHALGRTGETKEVSSVITFLASDSAS 117
N + PG I T KG+ S+ + EK GR G +E++++ FL SD AS
Sbjct: 235 FNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYAS 290
Query: 116 NITGVTIPVDGGRHAM 69
I G I DGG +
Sbjct: 291 WINGAVIKFDGGEEVL 306
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 84.6 bits (200), Expect = 4e-16
Identities = 63/256 (24%), Positives = 118/256 (46%), Gaps = 3/256 (1%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVV 648
F GKV ITG +G+G + L A V+ +R + L+ + + + NK+ +
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVH--AI 114
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV ++N + + I ++++NNA E S + + ++ + + G
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAF 174
Query: 467 LTMLATPYLVKT-KG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T+ L+K KG + ++++++ ++ +KA ++ ++ +A E G+R
Sbjct: 175 VTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMR 234
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLEK-CKSTHALGRTGETKEVSSVITFLASDSAS 117
N + PG I T KG+ S+ + EK GR G +E++++ FL SD AS
Sbjct: 235 FNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYAS 290
Query: 116 NITGVTIPVDGGRHAM 69
I G I DGG +
Sbjct: 291 WINGAVIKFDGGEEVL 306
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 84.6 bits (200), Expect = 4e-16
Identities = 63/256 (24%), Positives = 118/256 (46%), Gaps = 3/256 (1%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVV 648
F GKV ITG +G+G + L A V+ +R + L+ + + + NK+ +
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVH--AI 114
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV ++N + + I ++++NNA E S + + ++ + + G
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAF 174
Query: 467 LTMLATPYLVKT-KG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T+ L+K KG + ++++++ ++ +KA ++ ++ +A E G+R
Sbjct: 175 VTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMR 234
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLEK-CKSTHALGRTGETKEVSSVITFLASDSAS 117
N + PG I T KG+ S+ + EK GR G +E++++ FL SD AS
Sbjct: 235 FNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYAS 290
Query: 116 NITGVTIPVDGGRHAM 69
I G I DGG +
Sbjct: 291 WINGAVIKFDGGEEVL 306
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 84.6 bits (200), Expect = 4e-16
Identities = 63/256 (24%), Positives = 118/256 (46%), Gaps = 3/256 (1%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVV 648
F GKV ITG +G+G + L A V+ +R + L+ + + + NK+ +
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVH--AI 114
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV ++N + + I ++++NNA E S + + ++ + + G
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAF 174
Query: 467 LTMLATPYLVKT-KG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T+ L+K KG + ++++++ ++ +KA ++ ++ +A E G+R
Sbjct: 175 VTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMR 234
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLEK-CKSTHALGRTGETKEVSSVITFLASDSAS 117
N + PG I T KG+ S+ + EK GR G +E++++ FL SD AS
Sbjct: 235 FNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYAS 290
Query: 116 NITGVTIPVDGGRHAM 69
I G I DGG +
Sbjct: 291 WINGAVIKFDGGEEVL 306
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 84.2 bits (199), Expect = 6e-16
Identities = 57/199 (28%), Positives = 91/199 (45%), Gaps = 2/199 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKP--LVVV 645
K VL+TG SG G A + K+ E + ++ ++L+ L V
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVF 115
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
+E + + + + LVNNAGI G +E TSL+ Y V N+ G +
Sbjct: 116 RSEEVEKVVGDCPFEPEGPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRM 175
Query: 464 TMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVNA 285
T P + + KG +VN+SS+ G + P YCI+K ++ F+ C+ E+ P G++V+
Sbjct: 176 TKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSV 235
Query: 284 VNPGVILTGIHLKGSMSQQ 228
V PG + L S Q
Sbjct: 236 VEPGNFIAATSLYNPESIQ 254
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 84.2 bits (199), Expect = 6e-16
Identities = 67/202 (33%), Positives = 105/202 (51%), Gaps = 13/202 (6%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV++TGA++GIG ETA + A+ A + L R+ E E ++ E + + N+ + L
Sbjct: 37 VQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QVL 95
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + L VL+NNAG++ + + D ++ + N G
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP--YSKTADGFEMHIGVNHLGH 153
Query: 473 YLLTMLATPYLVKTKGS-IVNVSSVA---GLRSFPNI---------LAYCISKAALDQFT 333
+LLT L L ++ S IVNVSS+A G F N+ LAYC SK A FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 332 RCVALELAPKGIRVNAVNPGVI 267
+ +A L G+ +V+PG +
Sbjct: 214 QELARRLKGSGVTTYSVHPGTV 235
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 84.2 bits (199), Expect = 6e-16
Identities = 67/202 (33%), Positives = 105/202 (51%), Gaps = 13/202 (6%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV++TGA++GIG ETA + A+ A + L R+ E E ++ E + + N+ + L
Sbjct: 37 VQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QVL 95
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + L VL+NNAG++ + + D ++ + N G
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP--YSKTADGFEMHIGVNHLGH 153
Query: 473 YLLTMLATPYLVKTKGS-IVNVSSVA---GLRSFPNI---------LAYCISKAALDQFT 333
+LLT L L ++ S IVNVSS+A G F N+ LAYC SK A FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 332 RCVALELAPKGIRVNAVNPGVI 267
+ +A L G+ +V+PG +
Sbjct: 214 QELARRLKGSGVTTYSVHPGTV 235
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 84.2 bits (199), Expect = 6e-16
Identities = 67/202 (33%), Positives = 105/202 (51%), Gaps = 13/202 (6%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV++TGA++GIG ETA + A+ A + L R+ E E ++ E + + N+ + L
Sbjct: 37 VQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QVL 95
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + L VL+NNAG++ + + D ++ + N G
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP--YSKTADGFEMHIGVNHLGH 153
Query: 473 YLLTMLATPYLVKTKGS-IVNVSSVA---GLRSFPNI---------LAYCISKAALDQFT 333
+LLT L L ++ S IVNVSS+A G F N+ LAYC SK A FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 332 RCVALELAPKGIRVNAVNPGVI 267
+ +A L G+ +V+PG +
Sbjct: 214 QELARRLKGSGVTTYSVHPGTV 235
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 84.2 bits (199), Expect = 6e-16
Identities = 67/202 (33%), Positives = 105/202 (51%), Gaps = 13/202 (6%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV++TGA++GIG ETA + A+ A + L R+ E E ++ E + + N+ + L
Sbjct: 37 VQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QVL 95
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + L VL+NNAG++ + + D ++ + N G
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP--YSKTADGFEMHIGVNHLGH 153
Query: 473 YLLTMLATPYLVKTKGS-IVNVSSVA---GLRSFPNI---------LAYCISKAALDQFT 333
+LLT L L ++ S IVNVSS+A G F N+ LAYC SK A FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 332 RCVALELAPKGIRVNAVNPGVI 267
+ +A L G+ +V+PG +
Sbjct: 214 QELARRLKGSGVTTYSVHPGTV 235
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 84.2 bits (199), Expect = 6e-16
Identities = 67/202 (33%), Positives = 105/202 (51%), Gaps = 13/202 (6%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV++TGA++GIG ETA + A+ A + L R+ E E ++ E + + N+ + L
Sbjct: 37 VQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QVL 95
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + L VL+NNAG++ + + D ++ + N G
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP--YSKTADGFEMHIGVNHLGH 153
Query: 473 YLLTMLATPYLVKTKGS-IVNVSSVA---GLRSFPNI---------LAYCISKAALDQFT 333
+LLT L L ++ S IVNVSS+A G F N+ LAYC SK A FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 332 RCVALELAPKGIRVNAVNPGVI 267
+ +A L G+ +V+PG +
Sbjct: 214 QELARRLKGSGVTTYSVHPGTV 235
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 84.2 bits (199), Expect = 6e-16
Identities = 67/202 (33%), Positives = 105/202 (51%), Gaps = 13/202 (6%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV++TGA++GIG ETA + A+ A + L R+ E E ++ E + + N+ + L
Sbjct: 37 VQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QVL 95
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + L VL+NNAG++ + + D ++ + N G
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP--YSKTADGFEMHIGVNHLGH 153
Query: 473 YLLTMLATPYLVKTKGS-IVNVSSVA---GLRSFPNI---------LAYCISKAALDQFT 333
+LLT L L ++ S IVNVSS+A G F N+ LAYC SK A FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 332 RCVALELAPKGIRVNAVNPGVI 267
+ +A L G+ +V+PG +
Sbjct: 214 QELARRLKGSGVTTYSVHPGTV 235
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 84.2 bits (199), Expect = 6e-16
Identities = 67/202 (33%), Positives = 105/202 (51%), Gaps = 13/202 (6%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV++TGA++GIG ETA + A+ A + L R+ E E ++ E + + N+ + L
Sbjct: 37 VQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QVL 95
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + L VL+NNAG++ + + D ++ + N G
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP--YSKTADGFEMHIGVNHLGH 153
Query: 473 YLLTMLATPYLVKTKGS-IVNVSSVA---GLRSFPNI---------LAYCISKAALDQFT 333
+LLT L L ++ S IVNVSS+A G F N+ LAYC SK A FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 332 RCVALELAPKGIRVNAVNPGVI 267
+ +A L G+ +V+PG +
Sbjct: 214 QELARRLKGSGVTTYSVHPGTV 235
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 84.2 bits (199), Expect = 6e-16
Identities = 67/202 (33%), Positives = 105/202 (51%), Gaps = 13/202 (6%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV++TGA++GIG ETA + A+ A + L R+ E E ++ E + + N+ + L
Sbjct: 37 VQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QVL 95
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + L VL+NNAG++ + + D ++ + N G
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP--YSKTADGFEMHIGVNHLGH 153
Query: 473 YLLTMLATPYLVKTKGS-IVNVSSVA---GLRSFPNI---------LAYCISKAALDQFT 333
+LLT L L ++ S IVNVSS+A G F N+ LAYC SK A FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 332 RCVALELAPKGIRVNAVNPGVI 267
+ +A L G+ +V+PG +
Sbjct: 214 QELARRLKGSGVTTYSVHPGTV 235
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 83.4 bits (197), Expect = 1e-15
Identities = 66/202 (32%), Positives = 101/202 (50%), Gaps = 13/202 (6%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV+ITGA++GIG ETA + A A + + R+ E ++E V + L
Sbjct: 35 VQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEI-RVDTKNSQVL 93
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + + +L +L+NNAG++ + + D +++ + N G
Sbjct: 94 VRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCP--YSKTADGFETHLGVNHLGH 151
Query: 473 YLLTMLATPYL-VKTKGSIVNVSSVA---GLRSFPNI---------LAYCISKAALDQFT 333
+LLT L L V +VNVSSVA G F ++ AYC SK A FT
Sbjct: 152 FLLTYLLLEQLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFT 211
Query: 332 RCVALELAPKGIRVNAVNPGVI 267
R +A L G+ AV+PGV+
Sbjct: 212 RELAKRLQGTGVTTYAVHPGVV 233
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/185 (29%), Positives = 91/185 (49%), Gaps = 3/185 (1%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECE-HVSPNKLKPLVVV 645
G V++TG SSGIG A++ K A + L ARN++ L + E E H +K L +
Sbjct: 32 GAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCIS 91
Query: 644 ADVTME-SDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP-Y 471
DV+ + + ++N+I + + +D+LVN AG+ +G E+ + ++ +M+ N G Y
Sbjct: 92 VDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVY 151
Query: 470 LLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+ T + G IV VSS AG AY SK A+ + +E+ P + +
Sbjct: 152 PSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYI 211
Query: 290 NAVNP 276
P
Sbjct: 212 TVAYP 216
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/185 (29%), Positives = 91/185 (49%), Gaps = 3/185 (1%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECE-HVSPNKLKPLVVV 645
G V++TG SSGIG A++ K A + L ARN++ L + E E H +K L +
Sbjct: 32 GAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCIS 91
Query: 644 ADVTME-SDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP-Y 471
DV+ + + ++N+I + + +D+LVN AG+ +G E+ + ++ +M+ N G Y
Sbjct: 92 VDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVY 151
Query: 470 LLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+ T + G IV VSS AG AY SK A+ + +E+ P + +
Sbjct: 152 PSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYI 211
Query: 290 NAVNP 276
P
Sbjct: 212 TVAYP 216
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 83.0 bits (196), Expect = 1e-15
Identities = 55/185 (29%), Positives = 91/185 (49%), Gaps = 3/185 (1%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECE-HVSPNKLKPLVVV 645
G V++TG SSGIG A++ K A + L ARN++ L + E E H +K L +
Sbjct: 32 GAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCIS 91
Query: 644 ADVTME-SDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP-Y 471
DV+ + + ++N+I + + +D+LVN AG+ +G E+ + ++ +M+ N G Y
Sbjct: 92 VDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVY 151
Query: 470 LLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+ T + G IV VSS AG AY SK A+ + +E+ P + +
Sbjct: 152 PSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYI 211
Query: 290 NAVNP 276
P
Sbjct: 212 TVAYP 216
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 83.0 bits (196), Expect = 1e-15
Identities = 66/202 (32%), Positives = 101/202 (50%), Gaps = 13/202 (6%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV+ITGA++GIG ETA + A A + + R+ E ++E V + L
Sbjct: 35 VQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEI-RVDTKNSQVL 93
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + + +L +L+NNAG++ + + D +++ + N G
Sbjct: 94 VRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCP--YSKTADGFETHLGVNHLGH 151
Query: 473 YLLTMLATPYL-VKTKGSIVNVSSVA---GLRSFPNI---------LAYCISKAALDQFT 333
+LLT L L V +VNVSSVA G F ++ AYC SK A FT
Sbjct: 152 FLLTYLLLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFT 211
Query: 332 RCVALELAPKGIRVNAVNPGVI 267
R +A L G+ AV+PGV+
Sbjct: 212 RELAKRLQGTGVTTYAVHPGVV 233
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 80.6 bits (190), Expect = 7e-15
Identities = 61/252 (24%), Positives = 116/252 (46%), Gaps = 3/252 (1%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVV 648
F GKV ITG +G+G + L A V+ +R + L+ + + + NK+ +
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVH--AI 114
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV ++N + + I ++++NNA E S + + ++ + + G
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAF 174
Query: 467 LTMLATPYLVKT-KG-SIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T+ L+K KG + ++++++ ++ +KA ++ ++ +A E G+R
Sbjct: 175 VTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMR 234
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLEK-CKSTHALGRTGETKEVSSVITFLASDSAS 117
N + PG I T KG+ S+ + EK GR G +E++++ FL S AS
Sbjct: 235 FNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSGYAS 290
Query: 116 NITGVTIPVDGG 81
+ G I DGG
Sbjct: 291 WVNGAVIKFDGG 302
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 79.8 bits (188), Expect = 1e-14
Identities = 55/194 (28%), Positives = 88/194 (45%), Gaps = 4/194 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA SG+G AL FA+L + LVL NKE E+ +++
Sbjct: 39 AGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVR--AYT 96
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + + + + D+ + + +L+NNAGI+ + + + + N +
Sbjct: 97 CDCSQKEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 464 TMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALEL---APKGI 297
P ++ G +V +SS AGL + YC SK A F V +E KGI
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 296 RVNAVNPGVILTGI 255
+ V P I TG+
Sbjct: 217 KTTIVCPFFIKTGM 230
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 79.4 bits (187), Expect = 2e-14
Identities = 58/199 (29%), Positives = 98/199 (49%), Gaps = 8/199 (4%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVS-PNKLKPLVVVA 642
++ L+TGAS GIGA A + +V AR N+E+++AEC+ P L P
Sbjct: 12 RLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIP--YRC 69
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLT 462
D++ E DI ++ +Q + +D+ +NNAG+ ++ + S + + N NV + T
Sbjct: 70 DLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICT 129
Query: 461 MLATPYLVKTK---GSIVNVSSVAGLRSFPNILA--YCISKAALDQFTRCVALEL--APK 303
A + + G I+N++S++G R P + Y +K A+ T + EL A
Sbjct: 130 REAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQT 189
Query: 302 GIRVNAVNPGVILTGIHLK 246
IR ++PGV+ T K
Sbjct: 190 HIRATCISPGVVETQFAFK 208
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 79.4 bits (187), Expect = 2e-14
Identities = 58/199 (29%), Positives = 98/199 (49%), Gaps = 8/199 (4%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVS-PNKLKPLVVVA 642
++ L+TGAS GIGA A + +V AR N+E+++AEC+ P L P
Sbjct: 12 RLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIP--YRC 69
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLT 462
D++ E DI ++ +Q + +D+ +NNAG+ ++ + S + + N NV + T
Sbjct: 70 DLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICT 129
Query: 461 MLATPYLVKTK---GSIVNVSSVAGLRSFPNILA--YCISKAALDQFTRCVALEL--APK 303
A + + G I+N++S++G R P + Y +K A+ T + EL A
Sbjct: 130 REAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQT 189
Query: 302 GIRVNAVNPGVILTGIHLK 246
IR ++PGV+ T K
Sbjct: 190 HIRATCISPGVVETQFAFK 208
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 79.0 bits (186), Expect = 2e-14
Identities = 57/192 (29%), Positives = 102/192 (53%), Gaps = 5/192 (2%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G+ ++TG++ GIG A + AK +VL +R+K+ L+++S+E + K++ +
Sbjct: 50 GEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKF--KVETRTIAV 107
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVM----NTNVRGP 474
D E DI + I KT ++ +LVNN G+ + D+V+ N N+
Sbjct: 108 DFASE-DIYDKI-KTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSV 165
Query: 473 YLLTMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
+T L P +V ++KG+I+N+SS +G+ P + Y +K +D F++C+ E KG+
Sbjct: 166 CKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGV 225
Query: 296 RVNAVNPGVILT 261
V +V P + T
Sbjct: 226 FVQSVLPYFVAT 237
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 79.0 bits (186), Expect = 2e-14
Identities = 57/192 (29%), Positives = 102/192 (53%), Gaps = 5/192 (2%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G+ ++TG++ GIG A + AK +VL +R+K+ L+++S+E + K++ +
Sbjct: 50 GEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKF--KVETRTIAV 107
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVM----NTNVRGP 474
D E DI + I KT ++ +LVNN G+ + D+V+ N N+
Sbjct: 108 DFASE-DIYDKI-KTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSV 165
Query: 473 YLLTMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
+T L P +V ++KG+I+N+SS +G+ P + Y +K +D F++C+ E KG+
Sbjct: 166 CKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGV 225
Query: 296 RVNAVNPGVILT 261
V +V P + T
Sbjct: 226 FVQSVLPYFVAT 237
>U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 3 protein.
Length = 310
Score = 78.2 bits (184), Expect = 4e-14
Identities = 58/204 (28%), Positives = 101/204 (49%), Gaps = 5/204 (2%)
Frame = -2
Query: 851 WKLL*--LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHV 678
WK+L + G+ +ITGA GIG + + AK N+VL +R E LE I+ E E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 677 SPNKLKPLVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGIL--AAGSIENTSLDQYD 504
+ +K ++ AD T + ++I +K ++ +LVNN G+L S + D+
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAGL--EIGILVNNVGMLPNLLPSHFLNAPDEIQ 151
Query: 503 SVMNTNVRGPYLLTMLATPYL-VKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRC 327
S+++ N+ +T L ++ + KG I+N+SS L +P Y SKA + F++
Sbjct: 152 SLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKA 211
Query: 326 VALELAPKGIRVNAVNPGVILTGI 255
+ E K + + + P + T +
Sbjct: 212 LQEEYKAKEVIIQVLTPYAVSTAM 235
>CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein.
Length = 310
Score = 78.2 bits (184), Expect = 4e-14
Identities = 58/204 (28%), Positives = 101/204 (49%), Gaps = 5/204 (2%)
Frame = -2
Query: 851 WKLL*--LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHV 678
WK+L + G+ +ITGA GIG + + AK N+VL +R E LE I+ E E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 677 SPNKLKPLVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGIL--AAGSIENTSLDQYD 504
+ +K ++ AD T + ++I +K ++ +LVNN G+L S + D+
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAGL--EIGILVNNVGMLPNLLPSHFLNAPDEIQ 151
Query: 503 SVMNTNVRGPYLLTMLATPYL-VKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRC 327
S+++ N+ +T L ++ + KG I+N+SS L +P Y SKA + F++
Sbjct: 152 SLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKA 211
Query: 326 VALELAPKGIRVNAVNPGVILTGI 255
+ E K + + + P + T +
Sbjct: 212 LQEEYKAKEVIIQVLTPYAVSTAM 235
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 78.2 bits (184), Expect = 4e-14
Identities = 55/194 (28%), Positives = 87/194 (44%), Gaps = 4/194 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA SG+G AL FA+L + LVL NKE E+ ++
Sbjct: 39 AGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVH--AYT 96
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + + + + D+ + + +L+NNAGI+ + + + + N +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 464 TMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALEL---APKGI 297
P ++ G +V +SS AGL + YC SK A F V +E KGI
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 296 RVNAVNPGVILTGI 255
+ V P I TG+
Sbjct: 217 KTTIVCPFFIKTGM 230
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 78.2 bits (184), Expect = 4e-14
Identities = 55/194 (28%), Positives = 87/194 (44%), Gaps = 4/194 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA SG+G AL FA+L + LVL NKE E+ ++
Sbjct: 39 AGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVH--AYT 96
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + + + + D+ + + +L+NNAGI+ + + + + N +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 464 TMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALEL---APKGI 297
P ++ G +V +SS AGL + YC SK A F V +E KGI
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 296 RVNAVNPGVILTGI 255
+ V P I TG+
Sbjct: 217 KTTIVCPFFIKTGM 230
>BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 78.2 bits (184), Expect = 4e-14
Identities = 58/204 (28%), Positives = 101/204 (49%), Gaps = 5/204 (2%)
Frame = -2
Query: 851 WKLL*--LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHV 678
WK+L + G+ +ITGA GIG + + AK N+VL +R E LE I+ E E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 677 SPNKLKPLVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGIL--AAGSIENTSLDQYD 504
+ +K ++ AD T + ++I +K ++ +LVNN G+L S + D+
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAGL--EIGILVNNVGMLPNLLPSHFLNAPDEIQ 151
Query: 503 SVMNTNVRGPYLLTMLATPYL-VKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRC 327
S+++ N+ +T L ++ + KG I+N+SS L +P Y SKA + F++
Sbjct: 152 SLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKA 211
Query: 326 VALELAPKGIRVNAVNPGVILTGI 255
+ E K + + + P + T +
Sbjct: 212 LQEEYKAKEVIIQVLTPYAVSTAM 235
>AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 78.2 bits (184), Expect = 4e-14
Identities = 58/204 (28%), Positives = 101/204 (49%), Gaps = 5/204 (2%)
Frame = -2
Query: 851 WKLL*--LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHV 678
WK+L + G+ +ITGA GIG + + AK N+VL +R E LE I+ E E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 677 SPNKLKPLVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGIL--AAGSIENTSLDQYD 504
+ +K ++ AD T + ++I +K ++ +LVNN G+L S + D+
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAGL--EIGILVNNVGMLPNLLPSHFLNAPDEIQ 151
Query: 503 SVMNTNVRGPYLLTMLATPYL-VKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRC 327
S+++ N+ +T L ++ + KG I+N+SS L +P Y SKA + F++
Sbjct: 152 SLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKA 211
Query: 326 VALELAPKGIRVNAVNPGVILTGI 255
+ E K + + + P + T +
Sbjct: 212 LQEEYKAKEVIIQVLTPYAVSTAM 235
>AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 78.2 bits (184), Expect = 4e-14
Identities = 58/204 (28%), Positives = 101/204 (49%), Gaps = 5/204 (2%)
Frame = -2
Query: 851 WKLL*--LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHV 678
WK+L + G+ +ITGA GIG + + AK N+VL +R E LE I+ E E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 677 SPNKLKPLVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGIL--AAGSIENTSLDQYD 504
+ +K ++ AD T + ++I +K ++ +LVNN G+L S + D+
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAGL--EIGILVNNVGMLPNLLPSHFLNAPDEIQ 151
Query: 503 SVMNTNVRGPYLLTMLATPYL-VKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRC 327
S+++ N+ +T L ++ + KG I+N+SS L +P Y SKA + F++
Sbjct: 152 SLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKA 211
Query: 326 VALELAPKGIRVNAVNPGVILTGI 255
+ E K + + + P + T +
Sbjct: 212 LQEEYKAKEVIIQVLTPYAVSTAM 235
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 77.4 bits (182), Expect = 6e-14
Identities = 56/194 (28%), Positives = 93/194 (47%), Gaps = 4/194 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLV---LTARNKENLEKISAECEHVSPNKLKPL 654
S +V ITG SG G AL + ++ LT E+L+++++ H + L
Sbjct: 27 SNALVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTT------L 80
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRG 477
+ + D ++ + + L LVNNAG+ G + D + V+N N G
Sbjct: 81 LDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMG 139
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
P +T+ P L + +G ++N++SV G R N YC+SK L+ F+ + ++A GI
Sbjct: 140 PIGVTLALLPLLQQARGRVINITSVLG-RLAANGGGYCVSKFGLEAFSDSLRRDVAHFGI 198
Query: 296 RVNAVNPGVILTGI 255
RV+ V PG T +
Sbjct: 199 RVSIVEPGFFRTPV 212
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 77.4 bits (182), Expect = 6e-14
Identities = 61/190 (32%), Positives = 89/190 (46%), Gaps = 4/190 (2%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFA---KLEANLVLTARNKENLEKISAECEHVSPNKLKPLVV 648
+ VLI+G SSGIG E A+ A K +V T R+ E + A L V
Sbjct: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLT--VA 63
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV + + + + +DVLVNNAG+ G +E SL +V +TN G
Sbjct: 64 QLDVCSDESVAQCLSCIQGE---VDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVR 120
Query: 467 LTMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
L P + + + G IV +SSV GL+ Y SK AL+ F +A++L I +
Sbjct: 121 LVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFI 180
Query: 290 NAVNPGVILT 261
+ V PG ++T
Sbjct: 181 SLVEPGPVVT 190
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 76.6 bits (180), Expect = 1e-13
Identities = 56/194 (28%), Positives = 92/194 (47%), Gaps = 4/194 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLV---LTARNKENLEKISAECEHVSPNKLKPL 654
S V ITG SG G AL + ++ LT E+L+++++ H + L
Sbjct: 27 SNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTT------L 80
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRG 477
+ + D ++ + + L LVNNAG+ G + D + V+N N G
Sbjct: 81 LDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMG 139
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
P +T+ P L + +G ++N++SV G R N YC+SK L+ F+ + ++A GI
Sbjct: 140 PIGVTLALLPLLQQARGRVINITSVLG-RLAANGGGYCVSKFGLEAFSDSLRRDVAHFGI 198
Query: 296 RVNAVNPGVILTGI 255
RV+ V PG T +
Sbjct: 199 RVSIVEPGFFRTPV 212
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 76.6 bits (180), Expect = 1e-13
Identities = 56/194 (28%), Positives = 92/194 (47%), Gaps = 4/194 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLV---LTARNKENLEKISAECEHVSPNKLKPL 654
S V ITG SG G AL + ++ LT E+L+++++ H + L
Sbjct: 27 SNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTT------L 80
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRG 477
+ + D ++ + + L LVNNAG+ G + D + V+N N G
Sbjct: 81 LDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMG 139
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
P +T+ P L + +G ++N++SV G R N YC+SK L+ F+ + ++A GI
Sbjct: 140 PIGVTLALLPLLQQARGRVINITSVLG-RLAANGGGYCVSKFGLEAFSDSLRRDVAHFGI 198
Query: 296 RVNAVNPGVILTGI 255
RV+ V PG T +
Sbjct: 199 RVSIVEPGFFRTPV 212
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 75.8 bits (178), Expect = 2e-13
Identities = 56/178 (31%), Positives = 88/178 (49%), Gaps = 1/178 (0%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G VL+TGA++G+G E A +A+L ++LVLTA + L+K+ C + K+ + A
Sbjct: 29 GARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKV--FYIAA 86
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLV-NNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D+ ++++ +++ LD LV N+ G AG+ S +M N L
Sbjct: 87 DMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGT-RARSPQATRWLMQVNFVSYVQL 145
Query: 464 TMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
T A P L +KGS+V VSS+ G Y +K ALD F + EL + + V
Sbjct: 146 TSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 75.8 bits (178), Expect = 2e-13
Identities = 56/178 (31%), Positives = 88/178 (49%), Gaps = 1/178 (0%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G VL+TGA++G+G E A +A+L ++LVLTA + L+K+ C + K+ + A
Sbjct: 29 GARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKV--FYIAA 86
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLV-NNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D+ ++++ +++ LD LV N+ G AG+ S +M N L
Sbjct: 87 DMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGT-RARSPQATRWLMQVNFVSYVQL 145
Query: 464 TMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
T A P L +KGS+V VSS+ G Y +K ALD F + EL + + V
Sbjct: 146 TSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/188 (28%), Positives = 92/188 (48%), Gaps = 4/188 (2%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLT--ARNKENLEKISAECEHVSPN-KLKP 657
F G+VVL+TGA +G+G AL FA+ A +V+ + + + K S + V + +
Sbjct: 7 FDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRG 66
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
VA+ + + ++ ++ F ++DV+VNNAGIL S S + +D + ++RG
Sbjct: 67 GKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRG 126
Query: 476 PYLLTMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
+ +T A ++ K K G I+ SS +G+ Y +K L +A+E
Sbjct: 127 SFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSN 186
Query: 299 IRVNAVNP 276
I N + P
Sbjct: 187 IHCNTIAP 194
>BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 260
Score = 74.9 bits (176), Expect = 3e-13
Identities = 57/194 (29%), Positives = 97/194 (50%), Gaps = 5/194 (2%)
Frame = -2
Query: 851 WKLL*--LVMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHV 678
WK+L + G+ +ITGA GIG + + AK N+VL +R E LE I+ E E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 677 SPNKLKPLVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGIL--AAGSIENTSLDQYD 504
+ +K ++ AD T + ++I +K ++ +LVNN G+L S + D+
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAGL--EIGILVNNVGMLPNLLPSHFLNAPDEIQ 151
Query: 503 SVMNTNVRGPYLLTMLATPYL-VKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRC 327
S+++ N+ +T L ++ + KG I+N+SS L +P Y SKA + F++
Sbjct: 152 SLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKA 211
Query: 326 VALELAPKGIRVNA 285
+ E K + + A
Sbjct: 212 LQEEYKAKEVIIQA 225
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/188 (28%), Positives = 92/188 (48%), Gaps = 4/188 (2%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLT--ARNKENLEKISAECEHVSPN-KLKP 657
F G+VVL+TGA +G+G AL FA+ A +V+ + + + K S + V + +
Sbjct: 7 FDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRG 66
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
VA+ + + ++ ++ F ++DV+VNNAGIL S S + +D + ++RG
Sbjct: 67 GKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRG 126
Query: 476 PYLLTMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
+ +T A ++ K K G I+ SS +G+ Y +K L +A+E
Sbjct: 127 SFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSN 186
Query: 299 IRVNAVNP 276
I N + P
Sbjct: 187 IHCNTIAP 194
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 74.9 bits (176), Expect = 3e-13
Identities = 53/188 (28%), Positives = 92/188 (48%), Gaps = 4/188 (2%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLT--ARNKENLEKISAECEHVSPN-KLKP 657
F G+VVL+TGA +G+G AL FA+ A +V+ + + + K S + V + +
Sbjct: 7 FDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRG 66
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
VA+ + + ++ ++ F ++DV+VNNAGIL S S + +D + ++RG
Sbjct: 67 GKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRG 126
Query: 476 PYLLTMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKG 300
+ +T A ++ K K G I+ SS +G+ Y +K L +A+E
Sbjct: 127 SFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSN 186
Query: 299 IRVNAVNP 276
I N + P
Sbjct: 187 IHCNTIAP 194
>AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 74.5 bits (175), Expect = 5e-13
Identities = 70/250 (28%), Positives = 118/250 (47%), Gaps = 4/250 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
KV ITG SGIG A F + + TA K + + PL + D
Sbjct: 29 KVAFITGGGSGIGFRIAEIFMRHGCH---TAARK---------LAGATGRRCLPLSM--D 74
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAG---ILAAGSIENTSLDQYDSVMNTNVRGPYL 468
V + +D+ + +F ++D+L+N A + AG++ S + + +VM+ + G +
Sbjct: 75 VRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL---SFNAFKTVMDIDTSGTFN 131
Query: 467 LT-MLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
++ +L + G IVN+++ G R + +KAA+D TR +A+E P+ IRV
Sbjct: 132 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRV 191
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNI 111
N++ PG I +G +G + L + L R G E++ + +LAS AS +
Sbjct: 192 NSLAPGPI-SG--TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYV 248
Query: 110 TGVTIPVDGG 81
TG + DGG
Sbjct: 249 TGAVLVADGG 258
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 74.1 bits (174), Expect = 6e-13
Identities = 52/187 (27%), Positives = 83/187 (44%), Gaps = 4/187 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
+G++VLITGA SG+G AL FA+L + LVL NKE E+ ++
Sbjct: 39 AGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVH--AYT 96
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLL 465
D + + + + D+ + + +L+NNAGI+ + + + + N +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 464 TMLATPYLV-KTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALEL---APKGI 297
P ++ G +V +SS AGL + YC SK A F V +E KGI
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 296 RVNAVNP 276
+ V P
Sbjct: 217 KTTIVCP 223
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 73.7 bits (173), Expect = 8e-13
Identities = 61/193 (31%), Positives = 89/193 (46%), Gaps = 5/193 (2%)
Frame = -2
Query: 818 KVVLITGASSGIGAETA--LDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
K VL+TG G+G LD + N E++ C SP + V+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTC---SP---RLSVLQ 136
Query: 644 ADVTMESDIKNIIDKT--INQFNKLDVLVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGP 474
D+T IK+ K + Q L ++NNAG+L + E + Y M N G
Sbjct: 137 MDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T P L K+KG +VNVSS+ G + +Y SKAA+ F+ + LEL+ GI+
Sbjct: 197 VEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIK 256
Query: 293 VNAVNPGVILTGI 255
V ++ PG LT I
Sbjct: 257 VASIQPGGFLTNI 269
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 73.7 bits (173), Expect = 8e-13
Identities = 61/193 (31%), Positives = 89/193 (46%), Gaps = 5/193 (2%)
Frame = -2
Query: 818 KVVLITGASSGIGAETA--LDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
K VL+TG G+G LD + N E++ C SP + V+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTC---SP---RLSVLQ 136
Query: 644 ADVTMESDIKNIIDKT--INQFNKLDVLVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGP 474
D+T IK+ K + Q L ++NNAG+L + E + Y M N G
Sbjct: 137 MDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T P L K+KG +VNVSS+ G + +Y SKAA+ F+ + LEL+ GI+
Sbjct: 197 VEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIK 256
Query: 293 VNAVNPGVILTGI 255
V ++ PG LT I
Sbjct: 257 VASIQPGGFLTNI 269
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 73.7 bits (173), Expect = 8e-13
Identities = 61/193 (31%), Positives = 89/193 (46%), Gaps = 5/193 (2%)
Frame = -2
Query: 818 KVVLITGASSGIGAETA--LDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
K VL+TG G+G LD + N E++ C SP + V+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTC---SP---RLSVLQ 136
Query: 644 ADVTMESDIKNIIDKT--INQFNKLDVLVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGP 474
D+T IK+ K + Q L ++NNAG+L + E + Y M N G
Sbjct: 137 MDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T P L K+KG +VNVSS+ G + +Y SKAA+ F+ + LEL+ GI+
Sbjct: 197 VEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIK 256
Query: 293 VNAVNPGVILTGI 255
V ++ PG LT I
Sbjct: 257 VASIQPGGFLTNI 269
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 73.7 bits (173), Expect = 8e-13
Identities = 61/193 (31%), Positives = 89/193 (46%), Gaps = 5/193 (2%)
Frame = -2
Query: 818 KVVLITGASSGIGAETA--LDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
K VL+TG G+G LD + N E++ C SP + V+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTC---SP---RLSVLQ 136
Query: 644 ADVTMESDIKNIIDKT--INQFNKLDVLVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGP 474
D+T IK+ K + Q L ++NNAG+L + E + Y M N G
Sbjct: 137 MDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T P L K+KG +VNVSS+ G + +Y SKAA+ F+ + LEL+ GI+
Sbjct: 197 VEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIK 256
Query: 293 VNAVNPGVILTGI 255
V ++ PG LT I
Sbjct: 257 VASIQPGGFLTNI 269
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 73.7 bits (173), Expect = 8e-13
Identities = 61/193 (31%), Positives = 89/193 (46%), Gaps = 5/193 (2%)
Frame = -2
Query: 818 KVVLITGASSGIGAETA--LDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
K VL+TG G+G LD + N E++ C SP + V+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTC---SP---RLSVLQ 136
Query: 644 ADVTMESDIKNIIDKT--INQFNKLDVLVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGP 474
D+T IK+ K + Q L ++NNAG+L + E + Y M N G
Sbjct: 137 MDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T P L K+KG +VNVSS+ G + +Y SKAA+ F+ + LEL+ GI+
Sbjct: 197 VEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIK 256
Query: 293 VNAVNPGVILTGI 255
V ++ PG LT I
Sbjct: 257 VASIQPGGFLTNI 269
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 73.7 bits (173), Expect = 8e-13
Identities = 61/193 (31%), Positives = 89/193 (46%), Gaps = 5/193 (2%)
Frame = -2
Query: 818 KVVLITGASSGIGAETA--LDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
K VL+TG G+G LD + N E++ C SP + V+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTC---SP---RLSVLQ 136
Query: 644 ADVTMESDIKNIIDKT--INQFNKLDVLVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGP 474
D+T IK+ K + Q L ++NNAG+L + E + Y M N G
Sbjct: 137 MDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 473 YLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+T P L K+KG +VNVSS+ G + +Y SKAA+ F+ + LEL+ GI+
Sbjct: 197 VEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIK 256
Query: 293 VNAVNPGVILTGI 255
V ++ PG LT I
Sbjct: 257 VASIQPGGFLTNI 269
>BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein.
Length = 244
Score = 72.9 bits (171), Expect = 1e-12
Identities = 54/191 (28%), Positives = 97/191 (50%), Gaps = 4/191 (2%)
Frame = -2
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAG---ILAAGSIENTSLDQYDSVMNTNVRGPY 471
DV + +D+ + +F ++D+L+N A + AG++ S + + +VM+ + G +
Sbjct: 38 DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGAL---SFNAFKTVMDIDTSGTF 94
Query: 470 LLT-MLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
++ +L + G IVN+++ G R + +KAA+D TR +A+E P+ IR
Sbjct: 95 NVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIR 154
Query: 293 VNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASN 114
VN++ PG I +G +G + L + L R G E++ + +LAS AS
Sbjct: 155 VNSLAPGPI-SG--TEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASY 211
Query: 113 ITGVTIPVDGG 81
+TG + DGG
Sbjct: 212 VTGAVLVADGG 222
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 71.7 bits (168), Expect = 3e-12
Identities = 51/142 (35%), Positives = 76/142 (53%), Gaps = 1/142 (0%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
GKV+++T A+ GIG AL FA+ A ++ T N+ L+ E E + + V
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTR----VL 57
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLT 462
DVT K ID+ N+ +LDVL N AG + G++ + +D MN NVR YL+
Sbjct: 58 DVTK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113
Query: 461 MLATPYLVKTK-GSIVNVSSVA 399
P ++ K G+I+N+SSVA
Sbjct: 114 KAFLPKMLAQKSGNIINMSSVA 135
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 71.7 bits (168), Expect = 3e-12
Identities = 51/142 (35%), Positives = 76/142 (53%), Gaps = 1/142 (0%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
GKV+++T A+ GIG AL FA+ A ++ T N+ L+ E E + + V
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTR----VL 57
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLT 462
DVT K ID+ N+ +LDVL N AG + G++ + +D MN NVR YL+
Sbjct: 58 DVTK----KKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113
Query: 461 MLATPYLVKTK-GSIVNVSSVA 399
P ++ K G+I+N+SSVA
Sbjct: 114 KAFLPKMLAQKSGNIINMSSVA 135
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 70.9 bits (166), Expect = 6e-12
Identities = 55/169 (32%), Positives = 79/169 (46%), Gaps = 1/169 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKE-NLEKISAECEHVSPNKLKPLVV 648
+GKV L+TGA+ GIG A A + L N E ++ +A E P K L +
Sbjct: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT--LFI 61
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV + +++ K ++ F +LD+LVNNAG+ + E T SV + G YL
Sbjct: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNKKNWEKTLQINLVSV----ISGTYL 117
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
+ G I+N+SS+AGL YC SK + FTR A
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166
>AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein.
Length = 377
Score = 70.9 bits (166), Expect = 6e-12
Identities = 57/207 (27%), Positives = 101/207 (48%), Gaps = 15/207 (7%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G+ ++TGA+SGIG TAL+ A+ A +VL R++E E + + S N + + +
Sbjct: 36 GRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNN-EVIFMAL 94
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLT 462
D+ + ++ ++ +LD+L++NAGI + G + + ++ ++ N GP+LLT
Sbjct: 95 DLASLASVRAFATAFLSSEPRLDILIHNAGISSCG----RTREAFNLLLRVNHIGPFLLT 150
Query: 461 MLATPYLVKTKGS-IVNVSSVAGLRS--------------FPNILAYCISKAALDQFTRC 327
L P L S +V V+S A R + AY +K A F R
Sbjct: 151 HLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARE 210
Query: 326 VALELAPKGIRVNAVNPGVILTGIHLK 246
+A +L G+ A +PG + + + L+
Sbjct: 211 LANQLEATGVTCYAAHPGPVNSELFLR 237
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 59/200 (29%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G V +ITG +SG+G TA A+ VL E A+ + + N + A
Sbjct: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCV---FAPA 63
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENT------SLDQYDSVMNTNVR 480
DVT E D++ + +F ++DV VN AGI A N +L+ + V++ N+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 479 GPYLLTMLATPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
G + + L + + +G I+N +SVA AY SK + T +A
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 320 LELAPKGIRVNAVNPGVILT 261
+LAP GIRV + PG+ T
Sbjct: 184 RDLAPIGIRVMTIAPGLFGT 203
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 59/200 (29%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G V +ITG +SG+G TA A+ VL E A+ + + N + A
Sbjct: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCV---FAPA 63
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENT------SLDQYDSVMNTNVR 480
DVT E D++ + +F ++DV VN AGI A N +L+ + V++ N+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 479 GPYLLTMLATPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
G + + L + + +G I+N +SVA AY SK + T +A
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 320 LELAPKGIRVNAVNPGVILT 261
+LAP GIRV + PG+ T
Sbjct: 184 RDLAPIGIRVMTIAPGLFGT 203
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 59/200 (29%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G V +ITG +SG+G TA A+ VL E A+ + + N + A
Sbjct: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCV---FAPA 63
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENT------SLDQYDSVMNTNVR 480
DVT E D++ + +F ++DV VN AGI A N +L+ + V++ N+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 479 GPYLLTMLATPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
G + + L + + +G I+N +SVA AY SK + T +A
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 320 LELAPKGIRVNAVNPGVILT 261
+LAP GIRV + PG+ T
Sbjct: 184 RDLAPIGIRVMTIAPGLFGT 203
>CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein.
Length = 157
Score = 70.5 bits (165), Expect = 7e-12
Identities = 52/137 (37%), Positives = 71/137 (51%), Gaps = 2/137 (1%)
Frame = -2
Query: 428 GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVNAVNPGVIL--TGI 255
GSIVN+ V FP + ++A + T+ +ALE A GIR+N V PGVI T +
Sbjct: 6 GSIVNII-VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAV 64
Query: 254 HLKGSMSQQEYEIYLEKCKSTHALGRTGETKEVSSVITFLASDSASNITGVTIPVDGGRH 75
GS Q +E +K + R G +EVSSV+ FL +AS ITG ++ VDGGR
Sbjct: 65 ENYGSWGQSFFEGSFQKIPAK----RIGVPEEVSSVVCFLLPPAASFITGQSVDVDGGRS 120
Query: 74 AMCPR*GRP*NNNHQKG 24
P ++N KG
Sbjct: 121 LYTHSYEVPDHDNWPKG 137
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 59/200 (29%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G V +ITG +SG+G TA A+ VL E A+ + + N + A
Sbjct: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCV---FAPA 63
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENT------SLDQYDSVMNTNVR 480
DVT E D++ + +F ++DV VN AGI A N +L+ + V++ N+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 479 GPYLLTMLATPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
G + + L + + +G I+N +SVA AY SK + T +A
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 320 LELAPKGIRVNAVNPGVILT 261
+LAP GIRV + PG+ T
Sbjct: 184 RDLAPIGIRVMTIAPGLFGT 203
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 59/200 (29%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G V +ITG +SG+G TA A+ VL E A+ + + N + A
Sbjct: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCV---FAPA 63
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENT------SLDQYDSVMNTNVR 480
DVT E D++ + +F ++DV VN AGI A N +L+ + V++ N+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 479 GPYLLTMLATPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
G + + L + + +G I+N +SVA AY SK + T +A
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 320 LELAPKGIRVNAVNPGVILT 261
+LAP GIRV + PG+ T
Sbjct: 184 RDLAPIGIRVMTIAPGLFGT 203
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 59/200 (29%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G V +ITG +SG+G TA A+ VL E A+ + + N + A
Sbjct: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCV---FAPA 63
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENT------SLDQYDSVMNTNVR 480
DVT E D++ + +F ++DV VN AGI A N +L+ + V++ N+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 479 GPYLLTMLATPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
G + + L + + +G I+N +SVA AY SK + T +A
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 320 LELAPKGIRVNAVNPGVILT 261
+LAP GIRV + PG+ T
Sbjct: 184 RDLAPIGIRVMTIAPGLFGT 203
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 59/200 (29%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G V +ITG +SG+G TA A+ VL E A+ + + N + A
Sbjct: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCV---FAPA 63
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENT------SLDQYDSVMNTNVR 480
DVT E D++ + +F ++DV VN AGI A N +L+ + V++ N+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 479 GPYLLTMLATPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
G + + L + + +G I+N +SVA AY SK + T +A
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 320 LELAPKGIRVNAVNPGVILT 261
+LAP GIRV + PG+ T
Sbjct: 184 RDLAPIGIRVMTIAPGLFGT 203
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 70.5 bits (165), Expect = 7e-12
Identities = 59/200 (29%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G V +ITG +SG+G TA A+ VL E A+ + + N + A
Sbjct: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCV---FAPA 63
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENT------SLDQYDSVMNTNVR 480
DVT E D++ + +F ++DV VN AGI A N +L+ + V++ N+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 479 GPYLLTMLATPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
G + + L + + +G I+N +SVA AY SK + T +A
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 320 LELAPKGIRVNAVNPGVILT 261
+LAP GIRV + PG+ T
Sbjct: 184 RDLAPIGIRVMTIAPGLFGT 203
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 70.1 bits (164), Expect = 1e-11
Identities = 54/194 (27%), Positives = 90/194 (46%), Gaps = 4/194 (2%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLV---LTARNKENLEKISAECEHVSPNKLKPL 654
S V ITG SG G AL + ++ LT E+L+ +++ + + L
Sbjct: 27 SNAFVFITGCDSGFGRLLALQLDQKSFRVLASCLTPSGAEDLQGVASSGFNTT------L 80
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAA-GSIENTSLDQYDSVMNTNVRG 477
+ + D ++ + + L LVNNAG+ G + D + V+N N G
Sbjct: 81 LDITDPQSFQQAAKWVEMHVKEAG-LFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMG 139
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGI 297
P +T+ P L + +G ++N++SV G R N YC+SK L+ F+ + ++A GI
Sbjct: 140 PIGVTLALLPLLQQARGRVINITSVLG-RLAANGGGYCVSKFGLEAFSDSLRRDVAHFGI 198
Query: 296 RVNAVNPGVILTGI 255
R + V PG T +
Sbjct: 199 RESIVEPGFFRTPV 212
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 69.7 bits (163), Expect = 1e-11
Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 1/142 (0%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
GKV+++T A+ GIG AL FA+ A ++ T N+ L+ E E + + V
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQ----ELEKYPGIQTR----VL 57
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLT 462
DVT K ID+ ++ +LDVL N AG + G++ + +D MN NVR YL+
Sbjct: 58 DVTK----KKQIDQFASEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMI 113
Query: 461 MLATPYLVKTK-GSIVNVSSVA 399
P ++ K G+I+N+SSVA
Sbjct: 114 KAFLPKMLAQKSGNIINMSSVA 135
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 68.5 bits (160), Expect = 3e-11
Identities = 58/189 (30%), Positives = 84/189 (44%), Gaps = 3/189 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+ VLITG SG G ETA + ++ T + I E +L+ L + D
Sbjct: 83 RAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAI--ELRTCCSPRLRLLQM--D 138
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGIL-AAGSIENTSLDQYDSVMNTNVRGPYL 468
+T DI +++ T + LVNNAG E + + + S M N G
Sbjct: 139 LTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALE 198
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
LT P L ++G IV V S AG +P + AY SKAA+ + EL P G++V+
Sbjct: 199 LTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVS 258
Query: 287 AVNPGVILT 261
+ PG T
Sbjct: 259 IIQPGCFKT 267
>EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 68.5 bits (160), Expect = 3e-11
Identities = 58/189 (30%), Positives = 84/189 (44%), Gaps = 3/189 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+ VLITG SG G ETA + ++ T + I E +L+ L + D
Sbjct: 83 RAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAI--ELRTCCSPRLRLLQM--D 138
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGIL-AAGSIENTSLDQYDSVMNTNVRGPYL 468
+T DI +++ T + LVNNAG E + + + S M N G
Sbjct: 139 LTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALE 198
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
LT P L ++G IV V S AG +P + AY SKAA+ + EL P G++V+
Sbjct: 199 LTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVS 258
Query: 287 AVNPGVILT 261
+ PG T
Sbjct: 259 IIQPGCFKT 267
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 68.5 bits (160), Expect = 3e-11
Identities = 58/189 (30%), Positives = 84/189 (44%), Gaps = 3/189 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+ VLITG SG G ETA + ++ T + I E +L+ L + D
Sbjct: 83 RAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAI--ELRTCCSPRLRLLQM--D 138
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGIL-AAGSIENTSLDQYDSVMNTNVRGPYL 468
+T DI +++ T + LVNNAG E + + + S M N G
Sbjct: 139 LTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALE 198
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
LT P L ++G IV V S AG +P + AY SKAA+ + EL P G++V+
Sbjct: 199 LTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVS 258
Query: 287 AVNPGVILT 261
+ PG T
Sbjct: 259 IIQPGCFKT 267
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 68.5 bits (160), Expect = 3e-11
Identities = 58/189 (30%), Positives = 84/189 (44%), Gaps = 3/189 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+ VLITG SG G ETA + ++ T + I E +L+ L + D
Sbjct: 83 RAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAI--ELRTCCSPRLRLLQM--D 138
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGIL-AAGSIENTSLDQYDSVMNTNVRGPYL 468
+T DI +++ T + LVNNAG E + + + S M N G
Sbjct: 139 LTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALE 198
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
LT P L ++G IV V S AG +P + AY SKAA+ + EL P G++V+
Sbjct: 199 LTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVS 258
Query: 287 AVNPGVILT 261
+ PG T
Sbjct: 259 IIQPGCFKT 267
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 68.1 bits (159), Expect = 4e-11
Identities = 58/189 (30%), Positives = 84/189 (44%), Gaps = 3/189 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+ VLITG SG G ETA + ++ T + I E +L+ L + D
Sbjct: 83 RAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAI--ELRTCCSPRLRLLQM--D 138
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGIL-AAGSIENTSLDQYDSVMNTNVRGPYL 468
+T DI +++ T + LVNNAG E + + + S M N G
Sbjct: 139 LTKPGDISRLLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALE 198
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
LT P L ++G IV V S AG +P + AY SKAA+ + EL P G++V+
Sbjct: 199 LTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVS 258
Query: 287 AVNPGVILT 261
+ PG T
Sbjct: 259 IIQPGCFKT 267
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 67.7 bits (158), Expect = 5e-11
Identities = 68/240 (28%), Positives = 110/240 (45%), Gaps = 26/240 (10%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVL----TARNKE----------NLEKISAEC 687
+G+V LITGA SG+G AL+FA+ A LVL T N+E +LE A
Sbjct: 35 AGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAA 94
Query: 686 -------EHVSPN-KLKPLVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSI 531
E + P+ L+ DV ++ ++ + ++ VLVNNAG+++ +
Sbjct: 95 LQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHL 154
Query: 530 ENTSLDQYDSVMNTNVRGPYLLTMLATPYLVK-TKGSIVNVSSVAGLRSFPNILAYCISK 354
+ + M N + T P +++ G IV V+S GL S + YC SK
Sbjct: 155 LECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASK 214
Query: 353 AALDQFTRCVALEL--APK-GIRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHAL 183
+ F ++ EL A K GI+ V P ++ TG+ +G ++E E +L K + +
Sbjct: 215 FGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGM-FRGCRIRKEIEPFLPPLKPDYCV 273
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 67.7 bits (158), Expect = 5e-11
Identities = 68/240 (28%), Positives = 110/240 (45%), Gaps = 26/240 (10%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVL----TARNKE----------NLEKISAEC 687
+G+V LITGA SG+G AL+FA+ A LVL T N+E +LE A
Sbjct: 35 AGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAA 94
Query: 686 -------EHVSPN-KLKPLVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSI 531
E + P+ L+ DV ++ ++ + ++ VLVNNAG+++ +
Sbjct: 95 LQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHL 154
Query: 530 ENTSLDQYDSVMNTNVRGPYLLTMLATPYLVK-TKGSIVNVSSVAGLRSFPNILAYCISK 354
+ + M N + T P +++ G IV V+S GL S + YC SK
Sbjct: 155 LECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASK 214
Query: 353 AALDQFTRCVALEL--APK-GIRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHAL 183
+ F ++ EL A K GI+ V P ++ TG+ +G ++E E +L K + +
Sbjct: 215 FGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGM-FRGCRIRKEIEPFLPPLKPDYCV 273
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 67.7 bits (158), Expect = 5e-11
Identities = 68/240 (28%), Positives = 110/240 (45%), Gaps = 26/240 (10%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVL----TARNKE----------NLEKISAEC 687
+G+V LITGA SG+G AL+FA+ A LVL T N+E +LE A
Sbjct: 35 AGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAA 94
Query: 686 -------EHVSPN-KLKPLVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSI 531
E + P+ L+ DV ++ ++ + ++ VLVNNAG+++ +
Sbjct: 95 LQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHL 154
Query: 530 ENTSLDQYDSVMNTNVRGPYLLTMLATPYLVK-TKGSIVNVSSVAGLRSFPNILAYCISK 354
+ + M N + T P +++ G IV V+S GL S + YC SK
Sbjct: 155 LECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASK 214
Query: 353 AALDQFTRCVALEL--APK-GIRVNAVNPGVILTGIHLKGSMSQQEYEIYLEKCKSTHAL 183
+ F ++ EL A K GI+ V P ++ TG+ +G ++E E +L K + +
Sbjct: 215 FGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGM-FRGCRIRKEIEPFLPPLKPDYCV 273
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 67.3 bits (157), Expect = 7e-11
Identities = 58/189 (30%), Positives = 83/189 (43%), Gaps = 3/189 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+ VLITG SG G ETA + ++ T + I E +L+ L + D
Sbjct: 83 RAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAI--ELRTCCSPRLRLLQM--D 138
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGIL-AAGSIENTSLDQYDSVMNTNVRGPYL 468
+T DI ++ T + LVNNAG E + + + S M N G
Sbjct: 139 LTKPGDISRFLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALE 198
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
LT P L ++G IV V S AG +P + AY SKAA+ + EL P G++V+
Sbjct: 199 LTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVS 258
Query: 287 AVNPGVILT 261
+ PG T
Sbjct: 259 IIQPGCFKT 267
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 66.9 bits (156), Expect = 9e-11
Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 1/205 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
S K V ITG SG G A ++ +E +K+ + + L L V
Sbjct: 24 SEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTL--LDVT 81
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGI-LAAGSIENTSLDQYDSVMNTNVRGPYL 468
++++ + + DK Q L LVNNAG+ L +G E + D + V+N N+ G
Sbjct: 82 KSESIKAAAQWVRDKVGEQ--GLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + + +G +VN+SS G R YC+SK ++ F+ + EL G++V
Sbjct: 140 VTLHMLPMVKRARGRVVNMSSSGG-RVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVC 198
Query: 287 AVNPGVILTGIHLKGSMSQQEYEIY 213
+ PG T I K ++ + +++
Sbjct: 199 IIEPGNYRTAILGKENLESRMRKLW 223
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 66.9 bits (156), Expect = 9e-11
Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 1/205 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
S K V ITG SG G A ++ +E +K+ + + L L V
Sbjct: 24 SEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTL--LDVT 81
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGI-LAAGSIENTSLDQYDSVMNTNVRGPYL 468
++++ + + DK Q L LVNNAG+ L +G E + D + V+N N+ G
Sbjct: 82 KSESIKAAAQWVRDKVGEQ--GLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + + +G +VN+SS G R YC+SK ++ F+ + EL G++V
Sbjct: 140 VTLHMLPMVKRARGRVVNMSSSGG-RVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVC 198
Query: 287 AVNPGVILTGIHLKGSMSQQEYEIY 213
+ PG T I K ++ + +++
Sbjct: 199 IIEPGNYRTAILGKENLESRMRKLW 223
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 66.9 bits (156), Expect = 9e-11
Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 1/205 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
S K V ITG SG G A ++ +E +K+ + + L L V
Sbjct: 24 SEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTL--LDVT 81
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGI-LAAGSIENTSLDQYDSVMNTNVRGPYL 468
++++ + + DK Q L LVNNAG+ L +G E + D + V+N N+ G
Sbjct: 82 KSESIKAAAQWVRDKVGEQ--GLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + + +G +VN+SS G R YC+SK ++ F+ + EL G++V
Sbjct: 140 VTLHMLPMVKRARGRVVNMSSSGG-RVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVC 198
Query: 287 AVNPGVILTGIHLKGSMSQQEYEIY 213
+ PG T I K ++ + +++
Sbjct: 199 IIEPGNYRTAILGKENLESRMRKLW 223
>BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 14
(all-trans/9-cis/11-cis) protein.
Length = 336
Score = 65.3 bits (152), Expect = 3e-10
Identities = 61/217 (28%), Positives = 100/217 (46%), Gaps = 25/217 (11%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKI----------SAEC-E 684
+ GK VLITGA+SG+G TA + +L A +++ R++ E+ +AEC
Sbjct: 40 LMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGP 99
Query: 683 HVSPNKLKPLVV-VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQY 507
+ + L+V D+ ++ + + + +LDVL+NNAGI ++ D +
Sbjct: 100 EPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTE--DGF 157
Query: 506 DSVMNTNVRGPYLLTMLATPYLVKTKGS-IVNVSS------------VAGLRSFPNILAY 366
+ N G +LLT L L + S IV VSS + +S+ Y
Sbjct: 158 EMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCY 217
Query: 365 CISKAALDQFTRCVALELAPKGIRVNAVNPGVILTGI 255
SK A FTR +A L + VN ++PG++ T +
Sbjct: 218 SRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNL 254
>AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 65.3 bits (152), Expect = 3e-10
Identities = 61/217 (28%), Positives = 100/217 (46%), Gaps = 25/217 (11%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKI----------SAEC-E 684
+ GK VLITGA+SG+G TA + +L A +++ R++ E+ +AEC
Sbjct: 40 LMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGP 99
Query: 683 HVSPNKLKPLVV-VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQY 507
+ + L+V D+ ++ + + + +LDVL+NNAGI ++ D +
Sbjct: 100 EPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTE--DGF 157
Query: 506 DSVMNTNVRGPYLLTMLATPYLVKTKGS-IVNVSS------------VAGLRSFPNILAY 366
+ N G +LLT L L + S IV VSS + +S+ Y
Sbjct: 158 EMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCY 217
Query: 365 CISKAALDQFTRCVALELAPKGIRVNAVNPGVILTGI 255
SK A FTR +A L + VN ++PG++ T +
Sbjct: 218 SRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNL 254
>AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 65.3 bits (152), Expect = 3e-10
Identities = 61/217 (28%), Positives = 100/217 (46%), Gaps = 25/217 (11%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKI----------SAEC-E 684
+ GK VLITGA+SG+G TA + +L A +++ R++ E+ +AEC
Sbjct: 40 LMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGP 99
Query: 683 HVSPNKLKPLVV-VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQY 507
+ + L+V D+ ++ + + + +LDVL+NNAGI ++ D +
Sbjct: 100 EPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTE--DGF 157
Query: 506 DSVMNTNVRGPYLLTMLATPYLVKTKGS-IVNVSS------------VAGLRSFPNILAY 366
+ N G +LLT L L + S IV VSS + +S+ Y
Sbjct: 158 EMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCY 217
Query: 365 CISKAALDQFTRCVALELAPKGIRVNAVNPGVILTGI 255
SK A FTR +A L + VN ++PG++ T +
Sbjct: 218 SRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNL 254
>AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein.
Length = 336
Score = 65.3 bits (152), Expect = 3e-10
Identities = 61/217 (28%), Positives = 100/217 (46%), Gaps = 25/217 (11%)
Frame = -2
Query: 830 MFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKI----------SAEC-E 684
+ GK VLITGA+SG+G TA + +L A +++ R++ E+ +AEC
Sbjct: 40 LMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGP 99
Query: 683 HVSPNKLKPLVV-VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQY 507
+ + L+V D+ ++ + + + +LDVL+NNAGI ++ D +
Sbjct: 100 EPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTE--DGF 157
Query: 506 DSVMNTNVRGPYLLTMLATPYLVKTKGS-IVNVSS------------VAGLRSFPNILAY 366
+ N G +LLT L L + S IV VSS + +S+ Y
Sbjct: 158 EMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCY 217
Query: 365 CISKAALDQFTRCVALELAPKGIRVNAVNPGVILTGI 255
SK A FTR +A L + VN ++PG++ T +
Sbjct: 218 SRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNL 254
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 64.9 bits (151), Expect = 4e-10
Identities = 58/203 (28%), Positives = 91/203 (44%), Gaps = 6/203 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKI--SAECEHVSPNKLKPLV 651
VVLITG SSGIG A+ A + + T R+ + ++ +A P L+ L
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ DV + ++ ++DVLV NAG+ G +E D SV++ NV G
Sbjct: 65 L--DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+ P + + G ++ SV GL P YC SK AL+ +A+ L P G+
Sbjct: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180
Query: 293 VNAVNPGVILTGIHLKGSMSQQE 225
++ + G + T K S +E
Sbjct: 181 LSLIECGPVHTAFMEKVLGSPEE 203
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 64.9 bits (151), Expect = 4e-10
Identities = 58/203 (28%), Positives = 91/203 (44%), Gaps = 6/203 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKI--SAECEHVSPNKLKPLV 651
VVLITG SSGIG A+ A + + T R+ + ++ +A P L+ L
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ DV + ++ ++DVLV NAG+ G +E D SV++ NV G
Sbjct: 65 L--DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+ P + + G ++ SV GL P YC SK AL+ +A+ L P G+
Sbjct: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180
Query: 293 VNAVNPGVILTGIHLKGSMSQQE 225
++ + G + T K S +E
Sbjct: 181 LSLIECGPVHTAFMEKVLGSPEE 203
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 64.9 bits (151), Expect = 4e-10
Identities = 58/203 (28%), Positives = 91/203 (44%), Gaps = 6/203 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKI--SAECEHVSPNKLKPLV 651
VVLITG SSGIG A+ A + + T R+ + ++ +A P L+ L
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ DV + ++ ++DVLV NAG+ G +E D SV++ NV G
Sbjct: 65 L--DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+ P + + G ++ SV GL P YC SK AL+ +A+ L P G+
Sbjct: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180
Query: 293 VNAVNPGVILTGIHLKGSMSQQE 225
++ + G + T K S +E
Sbjct: 181 LSLIECGPVHTAFMEKVLGSPEE 203
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 64.9 bits (151), Expect = 4e-10
Identities = 58/203 (28%), Positives = 91/203 (44%), Gaps = 6/203 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKI--SAECEHVSPNKLKPLV 651
VVLITG SSGIG A+ A + + T R+ + ++ +A P L+ L
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ DV + ++ ++DVLV NAG+ G +E D SV++ NV G
Sbjct: 65 L--DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+ P + + G ++ SV GL P YC SK AL+ +A+ L P G+
Sbjct: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180
Query: 293 VNAVNPGVILTGIHLKGSMSQQE 225
++ + G + T K S +E
Sbjct: 181 LSLIECGPVHTAFMEKVLGSPEE 203
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 64.9 bits (151), Expect = 4e-10
Identities = 58/203 (28%), Positives = 91/203 (44%), Gaps = 6/203 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKI--SAECEHVSPNKLKPLV 651
VVLITG SSGIG A+ A + + T R+ + ++ +A P L+ L
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ DV + ++ ++DVLV NAG+ G +E D SV++ NV G
Sbjct: 65 L--DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+ P + + G ++ SV GL P YC SK AL+ +A+ L P G+
Sbjct: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180
Query: 293 VNAVNPGVILTGIHLKGSMSQQE 225
++ + G + T K S +E
Sbjct: 181 LSLIECGPVHTAFMEKVLGSPEE 203
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 64.9 bits (151), Expect = 4e-10
Identities = 58/203 (28%), Positives = 91/203 (44%), Gaps = 6/203 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKI--SAECEHVSPNKLKPLV 651
VVLITG SSGIG A+ A + + T R+ + ++ +A P L+ L
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ DV + ++ ++DVLV NAG+ G +E D SV++ NV G
Sbjct: 65 L--DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+ P + + G ++ SV GL P YC SK AL+ +A+ L P G+
Sbjct: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180
Query: 293 VNAVNPGVILTGIHLKGSMSQQE 225
++ + G + T K S +E
Sbjct: 181 LSLIECGPVHTAFMEKVLGSPEE 203
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 64.9 bits (151), Expect = 4e-10
Identities = 58/203 (28%), Positives = 91/203 (44%), Gaps = 6/203 (2%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKI--SAECEHVSPNKLKPLV 651
VVLITG SSGIG A+ A + + T R+ + ++ +A P L+ L
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ DV + ++ ++DVLV NAG+ G +E D SV++ NV G
Sbjct: 65 L--DVRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTV 120
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIR 294
+ P + + G ++ SV GL P YC SK AL+ +A+ L P G+
Sbjct: 121 RMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVH 180
Query: 293 VNAVNPGVILTGIHLKGSMSQQE 225
++ + G + T K S +E
Sbjct: 181 LSLIECGPVHTAFMEKVLGSPEE 203
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 64.1 bits (149), Expect = 6e-10
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K + ITG SG G A F K +++ + + AE + +L+ V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE----TSERLR--TVLLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
VT ++K NQ + + L+NNAG+ + +L+ Y + N+ G
Sbjct: 84 VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + K +G ++NVSSV G + Y SK A++ F + ++ G+ V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 287 AVNPGVILTGI 255
+ PG+ T +
Sbjct: 203 CIEPGLFKTNL 213
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 64.1 bits (149), Expect = 6e-10
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K + ITG SG G A F K +++ + + AE + +L+ V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE----TSERLR--TVLLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
VT ++K NQ + + L+NNAG+ + +L+ Y + N+ G
Sbjct: 84 VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + K +G ++NVSSV G + Y SK A++ F + ++ G+ V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 287 AVNPGVILTGI 255
+ PG+ T +
Sbjct: 203 CIEPGLFKTNL 213
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 64.1 bits (149), Expect = 6e-10
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K + ITG SG G A F K +++ + + AE + +L+ V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE----TSERLR--TVLLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
VT ++K NQ + + L+NNAG+ + +L+ Y + N+ G
Sbjct: 84 VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + K +G ++NVSSV G + Y SK A++ F + ++ G+ V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 287 AVNPGVILTGI 255
+ PG+ T +
Sbjct: 203 CIEPGLFKTNL 213
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 64.1 bits (149), Expect = 6e-10
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K + ITG SG G A F K +++ + + AE + +L+ V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE----TSERLR--TVLLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
VT ++K NQ + + L+NNAG+ + +L+ Y + N+ G
Sbjct: 84 VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + K +G ++NVSSV G + Y SK A++ F + ++ G+ V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 287 AVNPGVILTGI 255
+ PG+ T +
Sbjct: 203 CIEPGLFKTNL 213
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 64.1 bits (149), Expect = 6e-10
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K + ITG SG G A F K +++ + + AE + +L+ V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE----TSERLR--TVLLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
VT ++K NQ + + L+NNAG+ + +L+ Y + N+ G
Sbjct: 84 VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + K +G ++NVSSV G + Y SK A++ F + ++ G+ V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 287 AVNPGVILTGI 255
+ PG+ T +
Sbjct: 203 CIEPGLFKTNL 213
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 64.1 bits (149), Expect = 6e-10
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K + ITG SG G A F K +++ + + AE + +L+ V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE----TSERLR--TVLLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
VT ++K NQ + + L+NNAG+ + +L+ Y + N+ G
Sbjct: 84 VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + K +G ++NVSSV G + Y SK A++ F + ++ G+ V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 287 AVNPGVILTGI 255
+ PG+ T +
Sbjct: 203 CIEPGLFKTNL 213
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 64.1 bits (149), Expect = 6e-10
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K + ITG SG G A F K +++ + + AE + +L+ V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE----TSERLR--TVLLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
VT ++K NQ + + L+NNAG+ + +L+ Y + N+ G
Sbjct: 84 VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + K +G ++NVSSV G + Y SK A++ F + ++ G+ V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 287 AVNPGVILTGI 255
+ PG+ T +
Sbjct: 203 CIEPGLFKTNL 213
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 64.1 bits (149), Expect = 6e-10
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K + ITG SG G A F K +++ + + AE + +L+ V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE----TSERLR--TVLLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
VT ++K NQ + + L+NNAG+ + +L+ Y + N+ G
Sbjct: 84 VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + K +G ++NVSSV G + Y SK A++ F + ++ G+ V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 287 AVNPGVILTGI 255
+ PG+ T +
Sbjct: 203 CIEPGLFKTNL 213
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 64.1 bits (149), Expect = 6e-10
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K + ITG SG G A F K +++ + + AE + +L+ V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE----TSERLR--TVLLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
VT ++K NQ + + L+NNAG+ + +L+ Y + N+ G
Sbjct: 84 VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + K +G ++NVSSV G + Y SK A++ F + ++ G+ V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 287 AVNPGVILTGI 255
+ PG+ T +
Sbjct: 203 CIEPGLFKTNL 213
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 63.7 bits (148), Expect = 9e-10
Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 3/205 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K V ITG SG G A ++ ++ E++ + + ++L+ V D
Sbjct: 30 KYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKGAEQLRGQ----TSDRLE--TVTLD 83
Query: 638 VTMESDIKNIID--KTINQFNKLDVLVNNAGI-LAAGSIENTSLDQYDSVMNTNVRGPYL 468
VT + K + L LVNNAGI L E + + ++++ N+ G
Sbjct: 84 VTKTESVAAAAQWVKECVRDKGLWGLVNNAGISLPTAPNELLTKQDFVTILDVNLLGVID 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + K +G +VNVSSV G S YCISK ++ F+ + EL+ G++V
Sbjct: 144 VTLSLLPLVRKARGRVVNVSSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELSYFGVKVA 202
Query: 287 AVNPGVILTGIHLKGSMSQQEYEIY 213
+ PG T + K + EI+
Sbjct: 203 MIEPGYFKTAVTSKERFLKSFLEIW 227
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/186 (26%), Positives = 85/186 (45%), Gaps = 3/186 (1%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEAN-LVLTARNKENLEKISAECEHVSPNKLKPLVV 648
S + VLITG GIG + A +FA+ A +VL R ++ L++ + E + +
Sbjct: 37 SRESVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGT---ECHYF 93
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
+ DV ++ + + +LVNNA ++ S+ ++ D + N G +
Sbjct: 94 ICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFW 153
Query: 467 LTMLATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP-KGIR 294
T P +++ + G IV ++SV L + P + YC SKA+ F + L L G+
Sbjct: 154 TTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVS 213
Query: 293 VNAVNP 276
V P
Sbjct: 214 ATTVLP 219
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 3/182 (1%)
Frame = -2
Query: 812 VLITGASSGIGAETALDFAKLEAN-LVLTARNKENLEKISAECEHVSPNKLKPLVVVADV 636
VLITG GIG + A +FA+ A +VL R ++ L++ + E + + + DV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGT---ECHYFICDV 97
Query: 635 TMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTML 456
++ + + +LVNNA ++ S+ ++ D + N G + T
Sbjct: 98 GNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA 157
Query: 455 ATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP-KGIRVNAV 282
P +++ + G IV ++SV L + P + YC SKA+ F + L L G+ V
Sbjct: 158 FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTV 217
Query: 281 NP 276
P
Sbjct: 218 LP 219
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 3/182 (1%)
Frame = -2
Query: 812 VLITGASSGIGAETALDFAKLEAN-LVLTARNKENLEKISAECEHVSPNKLKPLVVVADV 636
VLITG GIG + A +FA+ A +VL R ++ L++ + E + + + DV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGT---ECHYFICDV 97
Query: 635 TMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTML 456
++ + + +LVNNA ++ S+ ++ D + N G + T
Sbjct: 98 GNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA 157
Query: 455 ATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP-KGIRVNAV 282
P +++ + G IV ++SV L + P + YC SKA+ F + L L G+ V
Sbjct: 158 FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTV 217
Query: 281 NP 276
P
Sbjct: 218 LP 219
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 3/182 (1%)
Frame = -2
Query: 812 VLITGASSGIGAETALDFAKLEAN-LVLTARNKENLEKISAECEHVSPNKLKPLVVVADV 636
VLITG GIG + A +FA+ A +VL R ++ L++ + E + + + DV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGT---ECHYFICDV 97
Query: 635 TMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTML 456
++ + + +LVNNA ++ S+ ++ D + N G + T
Sbjct: 98 GNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA 157
Query: 455 ATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP-KGIRVNAV 282
P +++ + G IV ++SV L + P + YC SKA+ F + L L G+ V
Sbjct: 158 FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTV 217
Query: 281 NP 276
P
Sbjct: 218 LP 219
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 3/182 (1%)
Frame = -2
Query: 812 VLITGASSGIGAETALDFAKLEAN-LVLTARNKENLEKISAECEHVSPNKLKPLVVVADV 636
VLITG GIG + A +FA+ A +VL R ++ L++ + E + + + DV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGT---ECHYFICDV 97
Query: 635 TMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTML 456
++ + + +LVNNA ++ S+ ++ D + N G + T
Sbjct: 98 GNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA 157
Query: 455 ATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP-KGIRVNAV 282
P +++ + G IV ++SV L + P + YC SKA+ F + L L G+ V
Sbjct: 158 FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTV 217
Query: 281 NP 276
P
Sbjct: 218 LP 219
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 62.9 bits (146), Expect = 1e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 3/182 (1%)
Frame = -2
Query: 812 VLITGASSGIGAETALDFAKLEAN-LVLTARNKENLEKISAECEHVSPNKLKPLVVVADV 636
VLITG GIG + A +FA+ A +VL R ++ L++ + E + + + DV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGT---ECHYFICDV 97
Query: 635 TMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTML 456
++ + + +LVNNA ++ S+ ++ D + N G + T
Sbjct: 98 GNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA 157
Query: 455 ATPYLVKTK-GSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAP-KGIRVNAV 282
P +++ + G IV ++SV L + P + YC SKA+ F + L L G+ V
Sbjct: 158 FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTV 217
Query: 281 NP 276
P
Sbjct: 218 LP 219
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/191 (26%), Positives = 89/191 (46%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K V ITG SG G A ++ ++ E++ + + ++L+ V D
Sbjct: 30 KYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQ----TSDRLE--TVTLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGPYL 468
VT I + LVNNAGIL ++ E + + +++ N+ G
Sbjct: 84 VTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQ 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + + +G IVNVSS+ G +F + YC+SK ++ F+ + E+ G++++
Sbjct: 144 VTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHFGVKIS 202
Query: 287 AVNPGVILTGI 255
V PG TG+
Sbjct: 203 IVEPGYFRTGM 213
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/191 (26%), Positives = 89/191 (46%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K V ITG SG G A ++ ++ E++ + + ++L+ V D
Sbjct: 30 KYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQ----TSDRLE--TVTLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGPYL 468
VT I + LVNNAGIL ++ E + + +++ N+ G
Sbjct: 84 VTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQ 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + + +G IVNVSS+ G +F + YC+SK ++ F+ + E+ G++++
Sbjct: 144 VTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHFGVKIS 202
Query: 287 AVNPGVILTGI 255
V PG TG+
Sbjct: 203 IVEPGYFRTGM 213
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 62.5 bits (145), Expect = 2e-09
Identities = 50/191 (26%), Positives = 89/191 (46%), Gaps = 3/191 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K V ITG SG G A ++ ++ E++ + + ++L+ V D
Sbjct: 30 KYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQ----TSDRLE--TVTLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAAGSI-ENTSLDQYDSVMNTNVRGPYL 468
VT I + LVNNAGIL ++ E + + +++ N+ G
Sbjct: 84 VTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQ 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + + +G IVNVSS+ G +F + YC+SK ++ F+ + E+ G++++
Sbjct: 144 VTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHFGVKIS 202
Query: 287 AVNPGVILTGI 255
V PG TG+
Sbjct: 203 IVEPGYFRTGM 213
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 62.1 bits (144), Expect = 3e-09
Identities = 40/126 (31%), Positives = 68/126 (53%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV++TGA++GIG ETA + A+ A + L R+ E E ++ E + + N+ + L
Sbjct: 37 VQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QVL 95
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + L VL+NNAG++ + + D ++ + N G
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP--YSKTADGFEMHIGVNHLGH 153
Query: 473 YLLTML 456
+LLT L
Sbjct: 154 FLLTHL 159
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 62.1 bits (144), Expect = 3e-09
Identities = 43/141 (30%), Positives = 67/141 (47%), Gaps = 13/141 (9%)
Frame = -2
Query: 644 ADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENT------SLDQYDSVMNTNV 483
ADVT E D++ + +F ++DV VN AGI A N +L+ + V++ N+
Sbjct: 13 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 72
Query: 482 RGPYLLTMLATPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCV 324
G + + L + + +G I+N +SVA AY SK + T +
Sbjct: 73 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 132
Query: 323 ALELAPKGIRVNAVNPGVILT 261
A +LAP GIRV + PG+ T
Sbjct: 133 ARDLAPIGIRVMTIAPGLFGT 153
>M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase
protein.
Length = 261
Score = 61.3 bits (142), Expect = 5e-09
Identities = 63/200 (31%), Positives = 96/200 (48%), Gaps = 15/200 (7%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
V L+TGAS G G A A L + LVL+ARN E L ++ AE + L+ + V
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELG-AERSGLRVVRVP 67
Query: 644 ADVTMESDIKNIID--KTINQFNKLD--VLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
AD+ E+ ++ ++ + + + L +L+NNAG L G + +D DS N
Sbjct: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSL--GDVSKGFVDLSDSTQVNNYWA 125
Query: 476 PYLLTMLA-TPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
L +ML T ++K ++VN+SS+ L+ F YC KAA D + +A
Sbjct: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185
Query: 320 LELAPKGIRVNAVNPGVILT 261
LE +RV PG + T
Sbjct: 186 LE--EPNVRVLNYAPGPLDT 203
>BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) protein.
Length = 261
Score = 61.3 bits (142), Expect = 5e-09
Identities = 63/200 (31%), Positives = 96/200 (48%), Gaps = 15/200 (7%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
V L+TGAS G G A A L + LVL+ARN E L ++ AE + L+ + V
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELG-AERSGLRVVRVP 67
Query: 644 ADVTMESDIKNIID--KTINQFNKLD--VLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
AD+ E+ ++ ++ + + + L +L+NNAG L G + +D DS N
Sbjct: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSL--GDVSKGFVDLSDSTQVNNYWA 125
Query: 476 PYLLTMLA-TPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
L +ML T ++K ++VN+SS+ L+ F YC KAA D + +A
Sbjct: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185
Query: 320 LELAPKGIRVNAVNPGVILT 261
LE +RV PG + T
Sbjct: 186 LE--EPNVRVLNYAPGPLDT 203
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 60.5 bits (140), Expect = 8e-09
Identities = 54/188 (28%), Positives = 83/188 (44%), Gaps = 13/188 (6%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G V +ITG +SG+G TA A+ VL E A+ + + N + A
Sbjct: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCV---FAPA 63
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENT------SLDQYDSVMNTNVR 480
DVT E D++ + +F ++DV VN AGI A N +L+ + V++ N+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 479 GPYLLTMLAT-------PYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
G + + L P +G I+N +SVA AY SK + T +A
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 320 LELAPKGI 297
+LAP G+
Sbjct: 184 RDLAPIGL 191
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 60.5 bits (140), Expect = 8e-09
Identities = 54/188 (28%), Positives = 83/188 (44%), Gaps = 13/188 (6%)
Frame = -2
Query: 821 GKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVA 642
G V +ITG +SG+G TA A+ VL E A+ + + N + A
Sbjct: 10 GLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGE---AQAKKLGNNCV---FAPA 63
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENT------SLDQYDSVMNTNVR 480
DVT E D++ + +F ++DV VN AGI A N +L+ + V++ N+
Sbjct: 64 DVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLM 123
Query: 479 GPYLLTMLAT-------PYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
G + + L P +G I+N +SVA AY SK + T +A
Sbjct: 124 GTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIA 183
Query: 320 LELAPKGI 297
+LAP G+
Sbjct: 184 RDLAPIGL 191
>AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) variant
protein.
Length = 261
Score = 60.5 bits (140), Expect = 8e-09
Identities = 63/200 (31%), Positives = 96/200 (48%), Gaps = 15/200 (7%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
V L+TGAS G G A A L + LVL+ARN E L ++ AE + L+ + V
Sbjct: 9 VRLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELG-AERSGLRVVRVP 67
Query: 644 ADVTMESDIKNIID--KTINQFNKLD--VLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
AD+ E+ ++ ++ + + + L +L+NNAG L G + +D DS N
Sbjct: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSL--GDVSKGFVDLSDSTQVNNYWA 125
Query: 476 PYLLTMLA-TPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
L +ML T ++K ++VN+SS+ L+ F YC KAA D + +A
Sbjct: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185
Query: 320 LELAPKGIRVNAVNPGVILT 261
LE +RV PG + T
Sbjct: 186 LE--EPNVRVLNYAPGPLDT 203
>M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -2
Query: 830 MFSG-KVVLITGASSGIGAETALDFAKL-EANLVLTARNKENLEKISAECEHVSPNKLKP 657
M SG V L+TG + GIG D +L ++VLTAR+ + + A + + L P
Sbjct: 1 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARD---VTRGQAAVQQLQAEGLSP 57
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
D+ I+ + D ++ LDVLVNNAGI + Q + M TN G
Sbjct: 58 RFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRS 387
+ P L+K +G +VNVSS+ +R+
Sbjct: 118 TRDVCTELLP-LIKPQGRVVNVSSIMSVRA 146
>J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -2
Query: 830 MFSG-KVVLITGASSGIGAETALDFAKL-EANLVLTARNKENLEKISAECEHVSPNKLKP 657
M SG V L+TG + GIG D +L ++VLTAR+ + + A + + L P
Sbjct: 1 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARD---VTRGQAAVQQLQAEGLSP 57
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
D+ I+ + D ++ LDVLVNNAGI + Q + M TN G
Sbjct: 58 RFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRS 387
+ P L+K +G +VNVSS+ +R+
Sbjct: 118 TRDVCTELLP-LIKPQGRVVNVSSIMSVRA 146
>EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -2
Query: 830 MFSG-KVVLITGASSGIGAETALDFAKL-EANLVLTARNKENLEKISAECEHVSPNKLKP 657
M SG V L+TG + GIG D +L ++VLTAR+ + + A + + L P
Sbjct: 1 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARD---VTRGQAAVQQLQAEGLSP 57
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
D+ I+ + D ++ LDVLVNNAGI + Q + M TN G
Sbjct: 58 RFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRS 387
+ P L+K +G +VNVSS+ +R+
Sbjct: 118 TRDVCTELLP-LIKPQGRVVNVSSIMSVRA 146
>CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein.
Length = 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -2
Query: 830 MFSG-KVVLITGASSGIGAETALDFAKL-EANLVLTARNKENLEKISAECEHVSPNKLKP 657
M SG V L+TG + GIG D +L ++VLTAR+ + + A + + L P
Sbjct: 1 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARD---VTRGQAAVQQLQAEGLSP 57
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
D+ I+ + D ++ LDVLVNNAGI + Q + M TN G
Sbjct: 58 RFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRS 387
+ P L+K +G +VNVSS+ +R+
Sbjct: 118 TRDVCTELLP-LIKPQGRVVNVSSIMSVRA 146
>CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 60.1 bits (139), Expect = 1e-08
Identities = 58/209 (27%), Positives = 97/209 (46%), Gaps = 20/209 (9%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+V ++TG + GIG TA A+L ++++ N +++ ++ + + N K + D
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYCD 102
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
+ + I+ + K + L VL+NNAG++ + + D ++ N G +LLT
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVP--QRKTRDGFEEHFGLNYLGHFLLTN 160
Query: 458 LATPYLVKTKGS------IVNVSS----VAGLR--------SFPNILAYCISKAALDQFT 333
L L K GS +V VSS VA L + AY SK AL FT
Sbjct: 161 LLLDTL-KESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 332 RCVALELAPKG--IRVNAVNPGVILTGIH 252
+ LA +G + N V+PGV+ T ++
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVY 248
>BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 60.1 bits (139), Expect = 1e-08
Identities = 58/209 (27%), Positives = 97/209 (46%), Gaps = 20/209 (9%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+V ++TG + GIG TA A+L ++++ N +++ ++ + + N K + D
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYCD 102
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
+ + I+ + K + L VL+NNAG++ + + D ++ N G +LLT
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVP--QRKTRDGFEEHFGLNYLGHFLLTN 160
Query: 458 LATPYLVKTKGS------IVNVSS----VAGLR--------SFPNILAYCISKAALDQFT 333
L L K GS +V VSS VA L + AY SK AL FT
Sbjct: 161 LLLDTL-KESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 332 RCVALELAPKG--IRVNAVNPGVILTGIH 252
+ LA +G + N V+PGV+ T ++
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVY 248
>BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -2
Query: 830 MFSG-KVVLITGASSGIGAETALDFAKL-EANLVLTARNKENLEKISAECEHVSPNKLKP 657
M SG V L+TG + GIG D +L ++VLTAR+ + + A + + L P
Sbjct: 1 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARD---VTRGQAAVQQLQAEGLSP 57
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
D+ I+ + D ++ LDVLVNNAGI + Q + M TN G
Sbjct: 58 RFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRS 387
+ P L+K +G +VNVSS+ +R+
Sbjct: 118 TRDVCTELLP-LIKPQGRVVNVSSIMSVRA 146
>BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein.
Length = 330
Score = 60.1 bits (139), Expect = 1e-08
Identities = 58/209 (27%), Positives = 97/209 (46%), Gaps = 20/209 (9%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+V ++TG + GIG TA A+L ++++ N +++ ++ + + N K + D
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYCD 102
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
+ + I+ + K + L VL+NNAG++ + + D ++ N G +LLT
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVP--QRKTRDGFEEHFGLNYLGHFLLTN 160
Query: 458 LATPYLVKTKGS------IVNVSS----VAGLR--------SFPNILAYCISKAALDQFT 333
L L K GS +V VSS VA L + AY SK AL FT
Sbjct: 161 LLLDTL-KESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 332 RCVALELAPKG--IRVNAVNPGVILTGIH 252
+ LA +G + N V+PGV+ T ++
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVY 248
>BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -2
Query: 830 MFSG-KVVLITGASSGIGAETALDFAKL-EANLVLTARNKENLEKISAECEHVSPNKLKP 657
M SG V L+TG + GIG D +L ++VLTAR+ + + A + + L P
Sbjct: 1 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARD---VTRGQAAVQQLQAEGLSP 57
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
D+ I+ + D ++ LDVLVNNAGI + Q + M TN G
Sbjct: 58 RFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRS 387
+ P L+K +G +VNVSS+ +R+
Sbjct: 118 TRDVCTELLP-LIKPQGRVVNVSSIMSVRA 146
>BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -2
Query: 830 MFSG-KVVLITGASSGIGAETALDFAKL-EANLVLTARNKENLEKISAECEHVSPNKLKP 657
M SG V L+TG + GIG D +L ++VLTAR+ + + A + + L P
Sbjct: 1 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARD---VTRGQAAVQQLQAEGLSP 57
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
D+ I+ + D ++ LDVLVNNAGI + Q + M TN G
Sbjct: 58 RFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRS 387
+ P L+K +G +VNVSS+ +R+
Sbjct: 118 TRDVCTELLP-LIKPQGRVVNVSSIMSVRA 146
>AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein.
Length = 330
Score = 60.1 bits (139), Expect = 1e-08
Identities = 58/209 (27%), Positives = 97/209 (46%), Gaps = 20/209 (9%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+V ++TG + GIG TA A+L ++++ N +++ ++ + + N K + D
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYCD 102
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
+ + I+ + K + L VL+NNAG++ + + D ++ N G +LLT
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVP--QRKTRDGFEEHFGLNYLGHFLLTN 160
Query: 458 LATPYLVKTKGS------IVNVSS----VAGLR--------SFPNILAYCISKAALDQFT 333
L L K GS +V VSS VA L + AY SK AL FT
Sbjct: 161 LLLDTL-KESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 332 RCVALELAPKG--IRVNAVNPGVILTGIH 252
+ LA +G + N V+PGV+ T ++
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVY 248
>AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase
(NAPDH)1, EC 1.1.1.184 protein.
Length = 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -2
Query: 830 MFSG-KVVLITGASSGIGAETALDFAKL-EANLVLTARNKENLEKISAECEHVSPNKLKP 657
M SG V L+TG + GIG D +L ++VLTAR+ + + A + + L P
Sbjct: 1 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARD---VTRGQAAVQQLQAEGLSP 57
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
D+ I+ + D ++ LDVLVNNAGI + Q + M TN G
Sbjct: 58 RFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRS 387
+ P L+K +G +VNVSS+ +R+
Sbjct: 118 TRDVCTELLP-LIKPQGRVVNVSSIMSVRA 146
>AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -2
Query: 830 MFSG-KVVLITGASSGIGAETALDFAKL-EANLVLTARNKENLEKISAECEHVSPNKLKP 657
M SG V L+TG + GIG D +L ++VLTAR+ + + A + + L P
Sbjct: 1 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARD---VTRGQAAVQQLQAEGLSP 57
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
D+ I+ + D ++ LDVLVNNAGI + Q + M TN G
Sbjct: 58 RFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRS 387
+ P L+K +G +VNVSS+ +R+
Sbjct: 118 TRDVCTELLP-LIKPQGRVVNVSSIMSVRA 146
>AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein.
Length = 198
Score = 60.1 bits (139), Expect = 1e-08
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 15/182 (8%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
V L+TGAS G G A A L + LVL+ARN E L ++ AE + L+ + V
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELG-AERSGLRVVRVP 67
Query: 644 ADVTMESDIKNIID--KTINQFNKLD--VLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
AD+ E+ ++ ++ + + + L +L+NNAG L G + +D DS N
Sbjct: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSL--GDVSKGFVDLSDSTQVNNYWA 125
Query: 476 PYLLTMLA-TPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
L +ML T ++K ++VN+SS+ L+ F YC KAA D + +A
Sbjct: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185
Query: 320 LE 315
LE
Sbjct: 186 LE 187
>AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -2
Query: 830 MFSG-KVVLITGASSGIGAETALDFAKL-EANLVLTARNKENLEKISAECEHVSPNKLKP 657
M SG V L+TG + GIG D +L ++VLTAR+ + + A + + L P
Sbjct: 1 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARD---VTRGQAAVQQLQAEGLSP 57
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
D+ I+ + D ++ LDVLVNNAGI + Q + M TN G
Sbjct: 58 RFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRS 387
+ P L+K +G +VNVSS+ +R+
Sbjct: 118 TRDVCTELLP-LIKPQGRVVNVSSIMSVRA 146
>AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase
protein.
Length = 198
Score = 60.1 bits (139), Expect = 1e-08
Identities = 58/182 (31%), Positives = 89/182 (48%), Gaps = 15/182 (8%)
Frame = -2
Query: 815 VVLITGASSGIGAETALDFAKLEAN---LVLTARNKENLEKISAECEHVSPNKLKPLVVV 645
V L+TGAS G G A A L + LVL+ARN E L ++ AE + L+ + V
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELG-AERSGLRVVRVP 67
Query: 644 ADVTMESDIKNIID--KTINQFNKLD--VLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
AD+ E+ ++ ++ + + + L +L+NNAG L G + +D DS N
Sbjct: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSL--GDVSKGFVDLSDSTQVNNYWA 125
Query: 476 PYLLTMLA-TPYLVKT-------KGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVA 321
L +ML T ++K ++VN+SS+ L+ F YC KAA D + +A
Sbjct: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185
Query: 320 LE 315
LE
Sbjct: 186 LE 187
>AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase
protein.
Length = 277
Score = 60.1 bits (139), Expect = 1e-08
Identities = 48/150 (32%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -2
Query: 830 MFSG-KVVLITGASSGIGAETALDFAKL-EANLVLTARNKENLEKISAECEHVSPNKLKP 657
M SG V L+TG + GIG D +L ++VLTAR+ + + A + + L P
Sbjct: 1 MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARD---VTRGQAAVQQLQAEGLSP 57
Query: 656 LVVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRG 477
D+ I+ + D ++ LDVLVNNAGI + Q + M TN G
Sbjct: 58 RFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFG 117
Query: 476 PYLLTMLATPYLVKTKGSIVNVSSVAGLRS 387
+ P L+K +G +VNVSS+ +R+
Sbjct: 118 TRDVCTELLP-LIKPQGRVVNVSSIMSVRA 146
>BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 330
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/209 (27%), Positives = 97/209 (46%), Gaps = 20/209 (9%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+V ++TG + GIG TA A+L ++++ N +++ ++ + + N K + D
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYCD 102
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
+ + I+ + K + L VL+NNAG++ + + D ++ N G +LLT
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVP--QRKTRDGFEEHFGLNYLGHFLLTN 160
Query: 458 LATPYLVKTKGS------IVNVSS----VAGLR--------SFPNILAYCISKAALDQFT 333
L L K GS +V VSS VA L + AY SK AL FT
Sbjct: 161 LLLDTL-KESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 332 RCVALELAPKG--IRVNAVNPGVILTGIH 252
+ LA +G + N V+PGV+ T ++
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDLY 248
>AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase
protein.
Length = 330
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/209 (27%), Positives = 97/209 (46%), Gaps = 20/209 (9%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
+V ++TG + GIG TA A+L ++++ N +++ ++ + + N K + D
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYCD 102
Query: 638 VTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLTM 459
+ + I+ + K + L VL+NNAG++ + + D ++ N G +LLT
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVP--QRKTRDGFEEHFGLNYLGHFLLTN 160
Query: 458 LATPYLVKTKGS------IVNVSS----VAGLR--------SFPNILAYCISKAALDQFT 333
L L K GS +V VSS VA L + AY SK AL FT
Sbjct: 161 LLLDTL-KESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 332 RCVALELAPKG--IRVNAVNPGVILTGIH 252
+ LA +G + N V+PGV+ T ++
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDLY 248
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 58.4 bits (135), Expect = 3e-08
Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 1/87 (1%)
Frame = -2
Query: 536 SIENTSLDQYDSVMNTNVRGPYLLTMLATPYLVKTKG-SIVNVSSVAGLRSFPNILAYCI 360
S+ + + + +D ++ NV+ P L+T P + K G S+V VSS+A P Y +
Sbjct: 1 SLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNV 60
Query: 359 SKAALDQFTRCVALELAPKGIRVNAVN 279
SK AL +A+ELAP+ IRVN ++
Sbjct: 61 SKTALLGLNNTLAIELAPRNIRVNCLH 87
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 58.4 bits (135), Expect = 3e-08
Identities = 55/206 (26%), Positives = 93/206 (45%), Gaps = 4/206 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K V ITG SG G A ++ ++ E++ + + ++L+ V D
Sbjct: 30 KYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKGAEQLRGQ----TSDRLE--TVTLD 83
Query: 638 VTMESDIKNIID--KTINQFNKLDVLVNNAGILAAGSIENTSLDQYD--SVMNTNVRGPY 471
VT + K + L LVNNAGI + + N L + D ++++ N+ G
Sbjct: 84 VTKTESVAAAAQWVKECVRDKGLWGLVNNAGI-SLPTAPNELLTKQDLLTILDVNLLGVI 142
Query: 470 LLTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRV 291
+T+ P + + +G +VNV SV G S YCISK ++ F+ + EL+ G++V
Sbjct: 143 DVTLNLLPLVRRARGRVVNVFSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELSYFGVKV 201
Query: 290 NAVNPGVILTGIHLKGSMSQQEYEIY 213
+ PG T + K + EI+
Sbjct: 202 AMIEPGYFKTAVTSKERFLKSFLEIW 227
>BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein.
Length = 305
Score = 58.0 bits (134), Expect = 4e-08
Identities = 60/202 (29%), Positives = 96/202 (47%), Gaps = 13/202 (6%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V GKVV++TGA++G A + L R+ E E ++ E + + N+ + L
Sbjct: 37 VQLPGKVVVVTGANTG-------------ARVYLACRDVEKGELVAKEIQTTTGNQ-QVL 82
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
V D++ I+ + + L VL+NNAG++ + + D ++ + N G
Sbjct: 83 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPY--SKTADGFEMHIGVNHLGH 140
Query: 473 YLLTMLATPYLVKTKGS-IVNVSSVA---GLRSFPNI---------LAYCISKAALDQFT 333
+LLT L L ++ S IVNV S+A G F N+ LAYC SK A FT
Sbjct: 141 FLLTHLLLEKLKESAPSRIVNVFSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 200
Query: 332 RCVALELAPKGIRVNAVNPGVI 267
+ +A L G+ +V+PG +
Sbjct: 201 QELARRLKGSGVTTYSVHPGTV 222
>BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein.
Length = 312
Score = 58.0 bits (134), Expect = 4e-08
Identities = 44/144 (30%), Positives = 67/144 (46%), Gaps = 1/144 (0%)
Frame = -2
Query: 833 VMFSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPL 654
V G+V L+TG +SGIG TAL+ AK + L R++ E E S N+
Sbjct: 31 VQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQ-NIF 89
Query: 653 VVVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGP 474
+ + D++ I ++ Q +KL VL+NNAG + + + D + N G
Sbjct: 90 LHIVDLSDPKQIWKFVE-NFKQEHKLHVLINNAGCMV--NKRELTEDGLEKNFAANTLGV 146
Query: 473 YLLTMLATPYLVKTKG-SIVNVSS 405
Y+LT P L K ++ VSS
Sbjct: 147 YILTTGLIPVLEKEHDPRVITVSS 170
>BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 13
(all-trans/9-cis) protein.
Length = 260
Score = 56.4 bits (130), Expect = 1e-07
Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 14/141 (9%)
Frame = -2
Query: 641 DVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYLLT 462
D+ I+ K I + ++D+L+NNAG++ T+ D ++ N G +LLT
Sbjct: 26 DLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHW--TTEDGFEMQFGVNHLGHFLLT 83
Query: 461 MLATPYLVKTKGS-IVNVSSVAGL-------------RSFPNILAYCISKAALDQFTRCV 324
L L + S I+N+SS+A + R + AYC SK A+ FT+ +
Sbjct: 84 NLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKEL 143
Query: 323 ALELAPKGIRVNAVNPGVILT 261
+ L G+ VNA++PGV T
Sbjct: 144 SRRLQGSGVTVNALHPGVART 164
>AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase
homolog isoform-1 protein.
Length = 279
Score = 56.4 bits (130), Expect = 1e-07
Identities = 46/182 (25%), Positives = 82/182 (45%), Gaps = 3/182 (1%)
Frame = -2
Query: 818 KVVLITGASSGIGAETALDFAKLEANLVLTARNKENLEKISAECEHVSPNKLKPLVVVAD 639
K + ITG SG G A F K +++ + + AE + +L+ V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE----TSERLR--TVLLD 83
Query: 638 VTMESDIKNIIDKTINQFNKLDV--LVNNAGILAA-GSIENTSLDQYDSVMNTNVRGPYL 468
VT ++K NQ + + L+NNAG+ + +L+ Y + N+ G
Sbjct: 84 VTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLIS 143
Query: 467 LTMLATPYLVKTKGSIVNVSSVAGLRSFPNILAYCISKAALDQFTRCVALELAPKGIRVN 288
+T+ P + K +G ++NVSSV G + Y SK A++ F + ++ G+ V+
Sbjct: 144 VTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVS 202
Query: 287 AV 282
+
Sbjct: 203 CI 204
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 1/143 (0%)
Frame = -2
Query: 824 SGKVVLITGASSGIGAETALDFAKLEANLVLTARNKE-NLEKISAECEHVSPNKLKPLVV 648
+GKV L+TGA+ GIG A A + L N E ++ +A E P K L +
Sbjct: 4 NGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKT--LFI 61
Query: 647 VADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPYL 468
DV + +++ K ++ F +LD+LVNNAG+ + E T SV + G YL
Sbjct: 62 QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSV----ISGTYL 117
Query: 467 LTMLATPYLVKTKGSIVNVSSVA 399
+ G I+N+SS+A
Sbjct: 118 GLDYMSKQNGGEGGIIINMSSLA 140
>AY256821-1|AAP94227.1| 526|Homo sapiens WOX8 isoform 8 protein.
Length = 526
Score = 54.8 bits (126), Expect = 4e-07
Identities = 61/215 (28%), Positives = 98/215 (45%), Gaps = 23/215 (10%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENL-EKISAECEHVSPNKLKPLV 651
F+GKVV++TGA+SGIG ETA FA A+++L RN E +S E +K K
Sbjct: 122 FTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEW--HKAKVET 179
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ D+ + +++ + + L VLV NA A + + D ++ N G +
Sbjct: 180 MTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALP--WSLTKDGLETTFQVNHLGHF 237
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVA----------GLRSFPNI----------LAYCISK 354
L L L ++ ++ VSS + G F + LAY SK
Sbjct: 238 YLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSK 297
Query: 353 AALDQFTRCVALELAPKGIRVNAVNPG-VILTGIH 252
F+ + L+P+G+ NAV+PG ++ + IH
Sbjct: 298 LCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIH 332
>AF325432-1|AAL05449.1| 414|Homo sapiens WW domain-containing
oxidoreductase isoform FORII protein.
Length = 414
Score = 54.8 bits (126), Expect = 4e-07
Identities = 61/215 (28%), Positives = 98/215 (45%), Gaps = 23/215 (10%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENL-EKISAECEHVSPNKLKPLV 651
F+GKVV++TGA+SGIG ETA FA A+++L RN E +S E +K K
Sbjct: 122 FTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEW--HKAKVEA 179
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ D+ + +++ + + L VLV NA A + + D ++ N G +
Sbjct: 180 MTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALP--WSLTKDGLETTFQVNHLGHF 237
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVA----------GLRSFPNI----------LAYCISK 354
L L L ++ ++ VSS + G F + LAY SK
Sbjct: 238 YLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSK 297
Query: 353 AALDQFTRCVALELAPKGIRVNAVNPG-VILTGIH 252
F+ + L+P+G+ NAV+PG ++ + IH
Sbjct: 298 LCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIH 332
>AF227527-1|AAF82054.1| 414|Homo sapiens FOR II protein protein.
Length = 414
Score = 54.8 bits (126), Expect = 4e-07
Identities = 61/215 (28%), Positives = 98/215 (45%), Gaps = 23/215 (10%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENL-EKISAECEHVSPNKLKPLV 651
F+GKVV++TGA+SGIG ETA FA A+++L RN E +S E +K K
Sbjct: 122 FTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEW--HKAKVET 179
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ D+ + +++ + + L VLV NA A + + D ++ N G +
Sbjct: 180 MTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALP--WSLTKDGLETTFQVNHLGHF 237
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVA----------GLRSFPNI----------LAYCISK 354
L L L ++ ++ VSS + G F + LAY SK
Sbjct: 238 YLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSATKNDYWAMLAYNRSK 297
Query: 353 AALDQFTRCVALELAPKGIRVNAVNPG-VILTGIH 252
F+ + L+P+G+ NAV+PG ++ + IH
Sbjct: 298 LCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIH 332
>AF227526-1|AAF82053.1| 363|Homo sapiens FOR I protein protein.
Length = 363
Score = 54.8 bits (126), Expect = 4e-07
Identities = 61/215 (28%), Positives = 98/215 (45%), Gaps = 23/215 (10%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENL-EKISAECEHVSPNKLKPLV 651
F+GKVV++TGA+SGIG ETA FA A+++L RN E +S E +K K
Sbjct: 122 FTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEW--HKAKVET 179
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ D+ + +++ + + L VLV NA A + + D ++ N G +
Sbjct: 180 MTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALP--WSLTKDGLETTFQVNHLGHF 237
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVA----------GLRSFPNI----------LAYCISK 354
L L L ++ ++ VSS + G F + LAY SK
Sbjct: 238 YLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSK 297
Query: 353 AALDQFTRCVALELAPKGIRVNAVNPG-VILTGIH 252
F+ + L+P+G+ NAV+PG ++ + IH
Sbjct: 298 LCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIH 332
>AF211943-1|AAF27049.1| 414|Homo sapiens WW domain-containing
protein WWOX protein.
Length = 414
Score = 54.8 bits (126), Expect = 4e-07
Identities = 61/215 (28%), Positives = 98/215 (45%), Gaps = 23/215 (10%)
Frame = -2
Query: 827 FSGKVVLITGASSGIGAETALDFAKLEANLVLTARNKENL-EKISAECEHVSPNKLKPLV 651
F+GKVV++TGA+SGIG ETA FA A+++L RN E +S E +K K
Sbjct: 122 FTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEW--HKAKVEA 179
Query: 650 VVADVTMESDIKNIIDKTINQFNKLDVLVNNAGILAAGSIENTSLDQYDSVMNTNVRGPY 471
+ D+ + +++ + + L VLV NA A + + D ++ N G +
Sbjct: 180 MTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALP--WSLTKDGLETTFQVNHLGHF 237
Query: 470 LLTMLATPYLVKT-KGSIVNVSSVA----------GLRSFPNI----------LAYCISK 354
L L L ++ ++ VSS + G F + LAY SK
Sbjct: 238 YLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSK 297
Query: 353 AALDQFTRCVALELAPKGIRVNAVNPG-VILTGIH 252
F+ + L+P+G+ NAV+PG ++ + IH
Sbjct: 298 LCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIH 332
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,851,925
Number of Sequences: 237096
Number of extensions: 2078366
Number of successful extensions: 4794
Number of sequences better than 10.0: 328
Number of HSP's better than 10.0 without gapping: 4223
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4376
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11326166088
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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