Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmmt16l06
(639 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 163 4e-40
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 163 4e-40
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 163 4e-40
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 163 4e-40
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 161 1e-39
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 161 2e-39
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 154 3e-37
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 154 3e-37
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 154 3e-37
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 139 9e-33
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 127 4e-29
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 85 3e-16
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 85 3e-16
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 85 3e-16
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 78 2e-14
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 78 2e-14
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 78 2e-14
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 75 2e-13
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 75 2e-13
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 75 2e-13
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 75 2e-13
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 75 2e-13
BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein. 57 5e-08
U83246-1|AAC15920.1| 537|Homo sapiens copine I protein. 35 0.28
CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein. 35 0.28
BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein. 35 0.28
AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein. 35 0.28
AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein. 35 0.28
AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein. 35 0.28
AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein. 35 0.28
BC066597-1|AAH66597.1| 537|Homo sapiens copine III protein. 33 1.1
BC036242-1|AAH36242.1| 537|Homo sapiens copine III protein. 33 1.1
AF077226-1|AAD46074.2| 537|Homo sapiens copine III protein. 33 1.1
AB014536-1|BAA31611.2| 540|Homo sapiens KIAA0636 protein protein. 33 1.1
BC053658-1|AAH53658.1| 548|Homo sapiens CPNE2 protein protein. 30 6.0
AF542551-1|AAQ09534.1| 446|Homo sapiens unknown protein. 30 6.0
AF492484-1|AAO85483.1| 548|Homo sapiens copine III-like related... 30 6.0
AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation ... 30 6.0
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 163 bits (397), Expect = 4e-40
Identities = 78/198 (39%), Positives = 117/198 (59%), Gaps = 1/198 (0%)
Frame = -2
Query: 638 AEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDI 459
A S K+GYP SR+PEFT+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 273 ASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQDA 330
Query: 458 TVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDD 279
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 331 EIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQ 388
Query: 278 RIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRT 102
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 389 RWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRV 448
Query: 101 PRKSAFVYKEILRSRVID 48
P SA Y +I+R+ ++
Sbjct: 449 PYTSAKEYAKIIRNNGLE 466
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 163 bits (397), Expect = 4e-40
Identities = 78/198 (39%), Positives = 117/198 (59%), Gaps = 1/198 (0%)
Frame = -2
Query: 638 AEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDI 459
A S K+GYP SR+PEFT+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 273 ASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQDA 330
Query: 458 TVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDD 279
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 331 EIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQ 388
Query: 278 RIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRT 102
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 389 RWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRV 448
Query: 101 PRKSAFVYKEILRSRVID 48
P SA Y +I+R+ ++
Sbjct: 449 PYTSAKEYAKIIRNNGLE 466
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 163 bits (397), Expect = 4e-40
Identities = 78/198 (39%), Positives = 117/198 (59%), Gaps = 1/198 (0%)
Frame = -2
Query: 638 AEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDI 459
A S K+GYP SR+PEFT+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 273 ASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQDA 330
Query: 458 TVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDD 279
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 331 EIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQ 388
Query: 278 RIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRT 102
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 389 RWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRV 448
Query: 101 PRKSAFVYKEILRSRVID 48
P SA Y +I+R+ ++
Sbjct: 449 PYTSAKEYAKIIRNNGLE 466
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 163 bits (397), Expect = 4e-40
Identities = 78/198 (39%), Positives = 117/198 (59%), Gaps = 1/198 (0%)
Frame = -2
Query: 638 AEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDI 459
A S K+GYP SR+PEFT+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 273 ASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQDA 330
Query: 458 TVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDD 279
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 331 EIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQ 388
Query: 278 RIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRT 102
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 389 RWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRV 448
Query: 101 PRKSAFVYKEILRSRVID 48
P SA Y +I+R+ ++
Sbjct: 449 PYTSAKEYAKIIRNNGLE 466
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 161 bits (392), Expect = 1e-39
Identities = 77/198 (38%), Positives = 116/198 (58%), Gaps = 1/198 (0%)
Frame = -2
Query: 638 AEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDI 459
A S K+GYP SR+PEFT+EE+++++G +DFF V +YT L+ E + + + L D
Sbjct: 273 ASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGTLQDA 330
Query: 458 TVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDD 279
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 331 EIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQ 388
Query: 278 RIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRT 102
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 389 RWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRV 448
Query: 101 PRKSAFVYKEILRSRVID 48
P SA Y +I+R+ ++
Sbjct: 449 PYTSAKEYAKIIRNNGLE 466
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 161 bits (391), Expect = 2e-39
Identities = 78/198 (39%), Positives = 116/198 (58%), Gaps = 1/198 (0%)
Frame = -2
Query: 638 AEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDI 459
A S K+GYP SR+PEFT+EE+++++G +DFF V + T L+ E + R + IL D
Sbjct: 273 ASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYCTTRLIKYQE--NKRGELGILQDA 330
Query: 458 TVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDD 279
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 331 EIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQ 388
Query: 278 RIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRT 102
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 389 RWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRV 448
Query: 101 PRKSAFVYKEILRSRVID 48
P SA Y +I+R+ ++
Sbjct: 449 PYTSAKEYAKIIRNNGLE 466
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 154 bits (373), Expect = 3e-37
Identities = 75/191 (39%), Positives = 104/191 (54%)
Frame = -2
Query: 635 EKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDIT 456
++S G SR+PEFT+ E+ + G DFFG NHYT L + + D
Sbjct: 1648 DRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA--DRG 1705
Query: 455 VGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDR 276
V + WP S S+WL ++P L +L++ YNDP Y+TENG S L D R
Sbjct: 1706 VASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTAR 1765
Query: 275 IRYYRAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPR 96
I Y R + L + + L+GY WS MDNFEW G++ERFGL+ V++SDP+ PR P+
Sbjct: 1766 IYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPK 1825
Query: 95 KSAFVYKEILR 63
SA Y ++R
Sbjct: 1826 ASAKFYASVVR 1836
Score = 127 bits (306), Expect = 4e-29
Identities = 73/182 (40%), Positives = 99/182 (54%), Gaps = 2/182 (1%)
Frame = -2
Query: 605 SRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWP 426
SR+P FT+EE+ +R +D F +N Y +V + P+ D + P WP
Sbjct: 1184 SRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWP 1241
Query: 425 QSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALES 246
+A +P L ++++ Y D YITENG N D DRI Y++ +
Sbjct: 1242 STAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINE 1298
Query: 245 VLDC--LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKE 72
L LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E
Sbjct: 1299 ALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTE 1357
Query: 71 IL 66
++
Sbjct: 1358 VI 1359
Score = 122 bits (295), Expect = 8e-28
Identities = 64/188 (34%), Positives = 111/188 (59%), Gaps = 5/188 (2%)
Frame = -2
Query: 614 YPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPP 435
+P +++PEFT+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 658 HPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNH 715
Query: 434 EWPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRY 267
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y
Sbjct: 716 VWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDY 774
Query: 266 YRAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKS 90
+ + VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKS
Sbjct: 775 FNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKS 834
Query: 89 AFVYKEIL 66
A+ + I+
Sbjct: 835 AYFFTSII 842
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 154 bits (373), Expect = 3e-37
Identities = 75/191 (39%), Positives = 104/191 (54%)
Frame = -2
Query: 635 EKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDIT 456
++S G SR+PEFT+ E+ + G DFFG NHYT L + + D
Sbjct: 1648 DRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA--DRG 1705
Query: 455 VGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDR 276
V + WP S S+WL ++P L +L++ YNDP Y+TENG S L D R
Sbjct: 1706 VASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTAR 1765
Query: 275 IRYYRAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPR 96
I Y R + L + + L+GY WS MDNFEW G++ERFGL+ V++SDP+ PR P+
Sbjct: 1766 IYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPK 1825
Query: 95 KSAFVYKEILR 63
SA Y ++R
Sbjct: 1826 ASAKFYASVVR 1836
Score = 127 bits (306), Expect = 4e-29
Identities = 73/182 (40%), Positives = 99/182 (54%), Gaps = 2/182 (1%)
Frame = -2
Query: 605 SRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWP 426
SR+P FT+EE+ +R +D F +N Y +V + P+ D + P WP
Sbjct: 1184 SRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWP 1241
Query: 425 QSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALES 246
+A +P L ++++ Y D YITENG N D DRI Y++ +
Sbjct: 1242 STAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINE 1298
Query: 245 VLDC--LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKE 72
L LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E
Sbjct: 1299 ALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTE 1357
Query: 71 IL 66
++
Sbjct: 1358 VI 1359
Score = 122 bits (295), Expect = 8e-28
Identities = 64/188 (34%), Positives = 111/188 (59%), Gaps = 5/188 (2%)
Frame = -2
Query: 614 YPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPP 435
+P +++PEFT+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 658 HPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNH 715
Query: 434 EWPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRY 267
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y
Sbjct: 716 VWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDY 774
Query: 266 YRAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKS 90
+ + VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKS
Sbjct: 775 FNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKS 834
Query: 89 AFVYKEIL 66
A+ + I+
Sbjct: 835 AYFFTSII 842
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 154 bits (373), Expect = 3e-37
Identities = 75/191 (39%), Positives = 104/191 (54%)
Frame = -2
Query: 635 EKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDIT 456
++S G SR+PEFT+ E+ + G DFFG NHYT L + + D
Sbjct: 1648 DRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA--DRG 1705
Query: 455 VGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDR 276
V + WP S S+WL ++P L +L++ YNDP Y+TENG S L D R
Sbjct: 1706 VASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTAR 1765
Query: 275 IRYYRAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPR 96
I Y R + L + + L+GY WS MDNFEW G++ERFGL+ V++SDP+ PR P+
Sbjct: 1766 IYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPK 1825
Query: 95 KSAFVYKEILR 63
SA Y ++R
Sbjct: 1826 ASAKFYASVVR 1836
Score = 127 bits (306), Expect = 4e-29
Identities = 73/182 (40%), Positives = 99/182 (54%), Gaps = 2/182 (1%)
Frame = -2
Query: 605 SRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWP 426
SR+P FT+EE+ +R +D F +N Y +V + P+ D + P WP
Sbjct: 1184 SRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWP 1241
Query: 425 QSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALES 246
+A +P L ++++ Y D YITENG N D DRI Y++ +
Sbjct: 1242 STAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINE 1298
Query: 245 VLDC--LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKE 72
L LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E
Sbjct: 1299 ALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTE 1357
Query: 71 IL 66
++
Sbjct: 1358 VI 1359
Score = 122 bits (295), Expect = 8e-28
Identities = 64/188 (34%), Positives = 111/188 (59%), Gaps = 5/188 (2%)
Frame = -2
Query: 614 YPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPP 435
+P +++PEFT+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 658 HPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNH 715
Query: 434 EWPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRY 267
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y
Sbjct: 716 VWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDY 774
Query: 266 YRAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKS 90
+ + VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKS
Sbjct: 775 FNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKS 834
Query: 89 AFVYKEIL 66
A+ + I+
Sbjct: 835 AYFFTSII 842
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 139 bits (336), Expect = 9e-33
Identities = 68/191 (35%), Positives = 105/191 (54%), Gaps = 2/191 (1%)
Frame = -2
Query: 632 KSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTG-FLVSANEQISDRPTIPILPDIT 456
KSA++G SR+P F+ +E+ ++G SDF G+ H+T ++ N P+ D+
Sbjct: 310 KSAEQGLEMSRLPVFSLQEKSYIKGTSDFLGLGHFTTRYITERNYPSRQGPSYQNDRDLI 369
Query: 455 VGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSP-PTNGLLDDD 279
+ P WP S WL P L + Q +Y DP Y+ ENG S L D+
Sbjct: 370 --ELVDPNWPDLGSKWLYSVPWGFRRLLNFAQTQYGDPPIYVMENGASQKFHCTQLCDEW 427
Query: 278 RIRYYRAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTP 99
RI+Y + + +L + G +KGY +WSL+D FEW +GY++R+G Y V+F+D +PR P
Sbjct: 428 RIQYLKGYINEMLKAIKDGANIKGYTSWSLLDKFEWEKGYSDRYGFYYVEFNDRNKPRYP 487
Query: 98 RKSAFVYKEIL 66
+ S YK+I+
Sbjct: 488 KASVQYYKKII 498
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 127 bits (306), Expect = 4e-29
Identities = 73/182 (40%), Positives = 99/182 (54%), Gaps = 2/182 (1%)
Frame = -2
Query: 605 SRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWP 426
SR+P FT+EE+ +R +D F +N Y +V + P+ D + P WP
Sbjct: 616 SRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWP 673
Query: 425 QSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALES 246
+A +P L ++++ Y D YITENG N D DRI Y++ +
Sbjct: 674 STAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINE 730
Query: 245 VLDC--LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKE 72
L LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E
Sbjct: 731 ALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTE 789
Query: 71 IL 66
++
Sbjct: 790 VI 791
Score = 122 bits (295), Expect = 8e-28
Identities = 64/188 (34%), Positives = 111/188 (59%), Gaps = 5/188 (2%)
Frame = -2
Query: 614 YPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPP 435
+P +++PEFT+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 90 HPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNH 147
Query: 434 EWPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRY 267
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y
Sbjct: 148 VWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDY 206
Query: 266 YRAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKS 90
+ + VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKS
Sbjct: 207 FNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKS 266
Query: 89 AFVYKEIL 66
A+ + I+
Sbjct: 267 AYFFTSII 274
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 84.6 bits (200), Expect = 3e-16
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Frame = -2
Query: 389 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 213
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 212 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 63
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 57.2 bits (132), Expect = 5e-08
Identities = 56/175 (32%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Frame = -2
Query: 623 KEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQI------SDRPTIPILPD 462
+ G S +P T+ ER L++G DF +NH+T V +EQ+ SDR I L D
Sbjct: 795 RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQD 852
Query: 461 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 282
IT S+ L + P + L ++++ Y D YIT +G + L+D
Sbjct: 853 IT---------RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID----DQALED 899
Query: 281 DRIRYYRAA--LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 126
DR+R Y L+ VL L +R+KGY A+ L + E RFG + DF
Sbjct: 900 DRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDF 949
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 84.6 bits (200), Expect = 3e-16
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Frame = -2
Query: 389 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 213
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 212 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 63
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 57.2 bits (132), Expect = 5e-08
Identities = 56/175 (32%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Frame = -2
Query: 623 KEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQI------SDRPTIPILPD 462
+ G S +P T+ ER L++G DF +NH+T V +EQ+ SDR I L D
Sbjct: 795 RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQD 852
Query: 461 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 282
IT S+ L + P + L ++++ Y D YIT +G + L+D
Sbjct: 853 IT---------RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID----DQALED 899
Query: 281 DRIRYYRAA--LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 126
DR+R Y L+ VL L +R+KGY A+ L + E RFG + DF
Sbjct: 900 DRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDF 949
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 84.6 bits (200), Expect = 3e-16
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Frame = -2
Query: 389 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 213
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 212 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 63
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 57.2 bits (132), Expect = 5e-08
Identities = 56/175 (32%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Frame = -2
Query: 623 KEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQI------SDRPTIPILPD 462
+ G S +P T+ ER L++G DF +NH+T V +EQ+ SDR I L D
Sbjct: 795 RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQD 852
Query: 461 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 282
IT S+ L + P + L ++++ Y D YIT +G + L+D
Sbjct: 853 IT---------RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID----DQALED 899
Query: 281 DRIRYYRAA--LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 126
DR+R Y L+ VL L +R+KGY A+ L + E RFG + DF
Sbjct: 900 DRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDF 949
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 78.2 bits (184), Expect = 2e-14
Identities = 32/58 (55%), Positives = 43/58 (74%)
Frame = -2
Query: 221 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 48
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 78.2 bits (184), Expect = 2e-14
Identities = 32/58 (55%), Positives = 43/58 (74%)
Frame = -2
Query: 221 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 48
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 78.2 bits (184), Expect = 2e-14
Identities = 32/58 (55%), Positives = 43/58 (74%)
Frame = -2
Query: 221 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 48
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = -2
Query: 401 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 228
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 116 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 174
Query: 227 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 66
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 175 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 228
Score = 56.8 bits (131), Expect = 6e-08
Identities = 55/188 (29%), Positives = 89/188 (47%), Gaps = 8/188 (4%)
Frame = -2
Query: 599 IPEFTDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPE 432
+P FT++E++L++G DF ++HYT LV + ++ +D + + DIT
Sbjct: 513 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT-------- 564
Query: 431 WPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY--- 264
W S S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 565 WLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQ 619
Query: 263 RAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAF 84
E++ + GI L GY A+S D RFGLY +D P+ K
Sbjct: 620 NYINEALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH-- 670
Query: 83 VYKEILRS 60
Y++I+ S
Sbjct: 671 -YRKIIDS 677
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = -2
Query: 401 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 228
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 227 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 66
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 56.8 bits (131), Expect = 6e-08
Identities = 55/188 (29%), Positives = 89/188 (47%), Gaps = 8/188 (4%)
Frame = -2
Query: 599 IPEFTDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPE 432
+P FT++E++L++G DF ++HYT LV + ++ +D + + DIT
Sbjct: 786 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT-------- 837
Query: 431 WPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY--- 264
W S S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 838 WLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQ 892
Query: 263 RAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAF 84
E++ + GI L GY A+S D RFGLY +D P+ K
Sbjct: 893 NYINEALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH-- 943
Query: 83 VYKEILRS 60
Y++I+ S
Sbjct: 944 -YRKIIDS 950
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = -2
Query: 401 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 228
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 227 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 66
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = -2
Query: 401 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 228
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 227 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 66
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 56.8 bits (131), Expect = 6e-08
Identities = 55/188 (29%), Positives = 89/188 (47%), Gaps = 8/188 (4%)
Frame = -2
Query: 599 IPEFTDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPE 432
+P FT++E++L++G DF ++HYT LV + ++ +D + + DIT
Sbjct: 786 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT-------- 837
Query: 431 WPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY--- 264
W S S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 838 WLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQ 892
Query: 263 RAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAF 84
E++ + GI L GY A+S D RFGLY +D P+ K
Sbjct: 893 NYINEALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH-- 943
Query: 83 VYKEILRS 60
Y++I+ S
Sbjct: 944 -YRKIIDS 950
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 2/114 (1%)
Frame = -2
Query: 401 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 228
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 227 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 66
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 56.8 bits (131), Expect = 6e-08
Identities = 55/188 (29%), Positives = 89/188 (47%), Gaps = 8/188 (4%)
Frame = -2
Query: 599 IPEFTDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPE 432
+P FT++E++L++G DF ++HYT LV + ++ +D + + DIT
Sbjct: 786 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT-------- 837
Query: 431 WPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY--- 264
W S S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 838 WLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQ 892
Query: 263 RAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAF 84
E++ + GI L GY A+S D RFGLY +D P+ K
Sbjct: 893 NYINEALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH-- 943
Query: 83 VYKEILRS 60
Y++I+ S
Sbjct: 944 -YRKIIDS 950
>BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein.
Length = 305
Score = 57.2 bits (132), Expect = 5e-08
Identities = 56/175 (32%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Frame = -2
Query: 623 KEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQI------SDRPTIPILPD 462
+ G S +P T+ ER L++G DF +NH+T V +EQ+ SDR I L D
Sbjct: 56 RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQD 113
Query: 461 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 282
IT S+ L + P + L ++++ Y D YIT +G + L+D
Sbjct: 114 IT---------RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID----DQALED 160
Query: 281 DRIRYYRAA--LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 126
DR+R Y L+ VL L +R+KGY A+ L + E RFG + DF
Sbjct: 161 DRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDF 210
>U83246-1|AAC15920.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 381
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 381
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 381
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein.
Length = 386
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 381
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 288 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 341
>AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein.
Length = 481
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 381
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 381
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein.
Length = 517
Score = 34.7 bits (76), Expect = 0.28
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 381
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 292 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 345
>BC066597-1|AAH66597.1| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 381
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>BC036242-1|AAH36242.1| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 381
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>AF077226-1|AAD46074.2| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 381
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>AB014536-1|BAA31611.2| 540|Homo sapiens KIAA0636 protein protein.
Length = 540
Score = 32.7 bits (71), Expect = 1.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 381
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 321 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 374
>BC053658-1|AAH53658.1| 548|Homo sapiens CPNE2 protein protein.
Length = 548
Score = 30.3 bits (65), Expect = 6.0
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 393
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 334 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 383
>AF542551-1|AAQ09534.1| 446|Homo sapiens unknown protein.
Length = 446
Score = 30.3 bits (65), Expect = 6.0
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 393
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 232 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 281
>AF492484-1|AAO85483.1| 548|Homo sapiens copine III-like related
protein protein.
Length = 548
Score = 30.3 bits (65), Expect = 6.0
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -2
Query: 542 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 393
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 334 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 383
>AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation
factor 1 variant protein.
Length = 208
Score = 30.3 bits (65), Expect = 6.0
Identities = 14/25 (56%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = -1
Query: 114 PPSHPAQV-RLRLQGDLEKQGHRPR 43
PP HPA + R R G L +GHRPR
Sbjct: 71 PPPHPASISRPRPPGPLPLRGHRPR 95
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,029,164
Number of Sequences: 237096
Number of extensions: 2239783
Number of successful extensions: 5001
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 4769
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4956
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7028963750
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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