Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmmt16k15
(809 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 108 2e-23
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 108 2e-23
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 108 2e-23
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 108 2e-23
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 103 6e-22
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 103 6e-22
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 103 6e-22
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 103 6e-22
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 103 6e-22
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 103 6e-22
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 103 6e-22
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 103 6e-22
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 103 6e-22
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 103 6e-22
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 103 8e-22
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 103 1e-21
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 103 1e-21
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 103 1e-21
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 103 1e-21
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 100 7e-21
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 92 2e-18
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 92 2e-18
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 92 2e-18
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 91 6e-18
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 86 2e-16
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 83 9e-16
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 81 6e-15
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 81 6e-15
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 77 8e-14
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 75 2e-13
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 75 2e-13
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 75 2e-13
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 75 2e-13
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 75 2e-13
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 75 2e-13
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 75 2e-13
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 75 2e-13
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 69 2e-11
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 69 2e-11
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 69 2e-11
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 69 2e-11
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 69 2e-11
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 69 2e-11
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 69 2e-11
CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein. 68 5e-11
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 67 6e-11
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 67 6e-11
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 67 6e-11
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 67 6e-11
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 67 6e-11
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 67 6e-11
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 66 1e-10
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 66 1e-10
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 66 1e-10
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 66 1e-10
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 66 1e-10
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 64 6e-10
BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein. 62 2e-09
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 62 2e-09
AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 62 2e-09
AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 62 2e-09
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 62 2e-09
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 62 2e-09
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 62 3e-09
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 61 4e-09
EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta... 61 4e-09
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 61 4e-09
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 61 4e-09
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 61 5e-09
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 61 5e-09
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 61 5e-09
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 61 5e-09
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 61 5e-09
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 60 9e-09
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 56 2e-07
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 56 2e-07
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 56 2e-07
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 56 2e-07
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 56 2e-07
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 56 2e-07
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 56 2e-07
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 56 2e-07
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 56 2e-07
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 56 2e-07
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 56 2e-07
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 55 3e-07
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 55 3e-07
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 55 3e-07
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 55 3e-07
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 55 3e-07
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 55 3e-07
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 55 3e-07
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 55 3e-07
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 55 3e-07
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 54 8e-07
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 54 8e-07
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 54 8e-07
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 54 8e-07
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 54 8e-07
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 54 8e-07
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 54 8e-07
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 53 1e-06
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 53 1e-06
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 53 1e-06
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 53 1e-06
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 53 1e-06
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 53 1e-06
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 53 1e-06
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 53 1e-06
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 2e-06
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 2e-06
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 2e-06
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 51 4e-06
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 51 4e-06
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 51 4e-06
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 51 4e-06
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 51 4e-06
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 51 4e-06
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 51 4e-06
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 51 4e-06
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 51 4e-06
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 51 4e-06
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 51 4e-06
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 51 4e-06
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 51 4e-06
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 51 4e-06
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 51 4e-06
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 51 6e-06
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 50 1e-05
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 48 5e-05
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 47 9e-05
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 47 9e-05
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 47 9e-05
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 47 9e-05
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 47 9e-05
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 47 9e-05
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 47 9e-05
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 47 9e-05
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 46 2e-04
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 46 2e-04
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 46 2e-04
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 46 2e-04
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 46 2e-04
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 46 2e-04
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 46 2e-04
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 46 2e-04
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 45 4e-04
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 45 4e-04
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 45 4e-04
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 44 5e-04
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 44 5e-04
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 44 7e-04
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 44 7e-04
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 44 7e-04
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 44 7e-04
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 44 9e-04
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 43 0.001
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 43 0.002
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 43 0.002
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 43 0.002
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 43 0.002
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 42 0.003
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 42 0.003
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 42 0.003
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 42 0.003
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 42 0.003
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 42 0.003
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 41 0.005
AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase... 41 0.005
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 41 0.006
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 41 0.006
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 41 0.006
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 41 0.006
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 41 0.006
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 41 0.006
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 41 0.006
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 41 0.006
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 41 0.006
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 40 0.008
DQ338571-1|ABC61321.1| 160|Homo sapiens NADP(H)-dependent retin... 40 0.008
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 40 0.008
AY943857-1|AAX49568.1| 57|Homo sapiens NADP(H)-dependent retin... 40 0.008
AY616183-1|AAT70758.1| 91|Homo sapiens NADP(H)-dependent retin... 40 0.008
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 40 0.008
AY268353-1|AAP42287.1| 199|Homo sapiens short-chain dehydrogena... 37 0.099
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 35 0.40
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.40
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.40
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 35 0.40
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 35 0.40
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.40
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.40
BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 1... 33 0.92
AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein. 33 0.92
AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein. 33 0.92
AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein. 33 0.92
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 33 1.6
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 33 1.6
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 33 1.6
Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta) ... 31 3.7
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 31 3.7
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 31 3.7
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 31 3.7
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 31 4.9
BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein. 31 6.5
BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein. 31 6.5
AY313896-1|AAP83168.1| 234|Homo sapiens short-chain dehydrogena... 31 6.5
AY268351-1|AAP42285.1| 205|Homo sapiens short-chain dehydrogena... 31 6.5
AF240697-1|AAF82747.1| 172|Homo sapiens retinol dehydrogenase h... 31 6.5
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 108 bits (260), Expect = 2e-23
Identities = 67/191 (35%), Positives = 99/191 (51%), Gaps = 1/191 (0%)
Frame = -2
Query: 742 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSI 566
I D+T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 565 YYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 386
Y LT LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVR
Sbjct: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 385 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 206
VNC++PG I T L A + LGR G+P EV A FLAS+ A+
Sbjct: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237
Query: 205 ITGASVPVDGG 173
TG + V GG
Sbjct: 238 CTGIELLVTGG 248
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 108 bits (260), Expect = 2e-23
Identities = 67/191 (35%), Positives = 99/191 (51%), Gaps = 1/191 (0%)
Frame = -2
Query: 742 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSI 566
I D+T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 565 YYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 386
Y LT LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVR
Sbjct: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 385 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 206
VNC++PG I T L A + LGR G+P EV A FLAS+ A+
Sbjct: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237
Query: 205 ITGASVPVDGG 173
TG + V GG
Sbjct: 238 CTGIELLVTGG 248
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 108 bits (260), Expect = 2e-23
Identities = 67/191 (35%), Positives = 99/191 (51%), Gaps = 1/191 (0%)
Frame = -2
Query: 742 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSI 566
I D+T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 565 YYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 386
Y LT LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVR
Sbjct: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 385 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 206
VNC++PG I T L A + LGR G+P EV A FLAS+ A+
Sbjct: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237
Query: 205 ITGASVPVDGG 173
TG + V GG
Sbjct: 238 CTGIELLVTGG 248
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 108 bits (260), Expect = 2e-23
Identities = 67/191 (35%), Positives = 99/191 (51%), Gaps = 1/191 (0%)
Frame = -2
Query: 742 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSI 566
I D+T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 565 YYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 386
Y LT LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVR
Sbjct: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 385 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASN 206
VNC++PG I T L A + LGR G+P EV A FLAS+ A+
Sbjct: 179 VNCISPGNIWTPLWEELAALMPDPRASIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANF 237
Query: 205 ITGASVPVDGG 173
TG + V GG
Sbjct: 238 CTGIELLVTGG 248
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 103 bits (248), Expect = 6e-22
Identities = 61/186 (32%), Positives = 103/186 (55%), Gaps = 2/186 (1%)
Frame = -2
Query: 724 KESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTML 548
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 92 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 151
Query: 547 AVPHLLESKGXXXXXXXXNGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 371
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 152 VVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 211
Query: 370 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 191
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG +
Sbjct: 212 PGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGET 267
Query: 190 VPVDGG 173
V V GG
Sbjct: 268 VVVGGG 273
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 103 bits (248), Expect = 6e-22
Identities = 61/186 (32%), Positives = 103/186 (55%), Gaps = 2/186 (1%)
Frame = -2
Query: 724 KESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTML 548
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 92 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 151
Query: 547 AVPHLLESKGXXXXXXXXNGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 371
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 152 VVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 211
Query: 370 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 191
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG +
Sbjct: 212 PGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGET 267
Query: 190 VPVDGG 173
V V GG
Sbjct: 268 VVVGGG 273
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 103 bits (248), Expect = 6e-22
Identities = 62/198 (31%), Positives = 98/198 (49%)
Frame = -2
Query: 763 KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMN 584
K A + I ++ E ++ ++K T+D +GK++ LVNN G E+ S + ++
Sbjct: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129
Query: 583 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL 404
TN+ +Y+ ++ G FP + ++A V T+ +ALE
Sbjct: 130 TNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189
Query: 403 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 224
A G+R+NCV PGVI ++ S Q +F E + + R G P+EV++ + FL
Sbjct: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQ--SFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247
Query: 223 SDLASNITGASVPVDGGR 170
S AS ITG SV VDGGR
Sbjct: 248 SPAASFITGQSVDVDGGR 265
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 103 bits (248), Expect = 6e-22
Identities = 61/186 (32%), Positives = 103/186 (55%), Gaps = 2/186 (1%)
Frame = -2
Query: 724 KESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTML 548
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 92 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 151
Query: 547 AVPHLLESKGXXXXXXXXNGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 371
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 152 VVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 211
Query: 370 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 191
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG +
Sbjct: 212 PGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGET 267
Query: 190 VPVDGG 173
V V GG
Sbjct: 268 VVVGGG 273
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 103 bits (248), Expect = 6e-22
Identities = 61/186 (32%), Positives = 103/186 (55%), Gaps = 2/186 (1%)
Frame = -2
Query: 724 KESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTML 548
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 92 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 151
Query: 547 AVPHLLESKGXXXXXXXXNGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 371
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 152 VVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 211
Query: 370 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 191
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG +
Sbjct: 212 PGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGET 267
Query: 190 VPVDGG 173
V V GG
Sbjct: 268 VVVGGG 273
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 103 bits (248), Expect = 6e-22
Identities = 62/198 (31%), Positives = 98/198 (49%)
Frame = -2
Query: 763 KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMN 584
K A + I ++ E ++ ++K T+D +GK++ LVNN G E+ S + ++
Sbjct: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129
Query: 583 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL 404
TN+ +Y+ ++ G FP + ++A V T+ +ALE
Sbjct: 130 TNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189
Query: 403 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 224
A G+R+NCV PGVI ++ S Q +F E + + R G P+EV++ + FL
Sbjct: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQ--SFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247
Query: 223 SDLASNITGASVPVDGGR 170
S AS ITG SV VDGGR
Sbjct: 248 SPAASFITGQSVDVDGGR 265
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 103 bits (248), Expect = 6e-22
Identities = 62/198 (31%), Positives = 98/198 (49%)
Frame = -2
Query: 763 KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMN 584
K A + I ++ E ++ ++K T+D +GK++ LVNN G E+ S + ++
Sbjct: 89 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 148
Query: 583 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL 404
TN+ +Y+ ++ G FP + ++A V T+ +ALE
Sbjct: 149 TNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 208
Query: 403 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 224
A G+R+NCV PGVI ++ S Q +F E + + R G P+EV++ + FL
Sbjct: 209 ACSGIRINCVAPGVIYSQTAVENYGSWGQ--SFFEGSFQKIPAKRIGVPEEVSSVVCFLL 266
Query: 223 SDLASNITGASVPVDGGR 170
S AS ITG SV VDGGR
Sbjct: 267 SPAASFITGQSVDVDGGR 284
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 103 bits (248), Expect = 6e-22
Identities = 61/186 (32%), Positives = 103/186 (55%), Gaps = 2/186 (1%)
Frame = -2
Query: 724 KESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTML 548
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 92 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 151
Query: 547 AVPHLLESKGXXXXXXXXNGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 371
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 152 VVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 211
Query: 370 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 191
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG +
Sbjct: 212 PGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGET 267
Query: 190 VPVDGG 173
V V GG
Sbjct: 268 VVVGGG 273
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 103 bits (248), Expect = 6e-22
Identities = 62/198 (31%), Positives = 98/198 (49%)
Frame = -2
Query: 763 KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMN 584
K A + I ++ E ++ ++K T+D +GK++ LVNN G E+ S + ++
Sbjct: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLE 129
Query: 583 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL 404
TN+ +Y+ ++ G FP + ++A V T+ +ALE
Sbjct: 130 TNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189
Query: 403 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 224
A G+R+NCV PGVI ++ S Q +F E + + R G P+EV++ + FL
Sbjct: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQ--SFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247
Query: 223 SDLASNITGASVPVDGGR 170
S AS ITG SV VDGGR
Sbjct: 248 SPAASFITGQSVDVDGGR 265
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 103 bits (248), Expect = 6e-22
Identities = 61/186 (32%), Positives = 103/186 (55%), Gaps = 2/186 (1%)
Frame = -2
Query: 724 KESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTML 548
K D E+++ + +G +D+LV+NA + G+I + + +D+ ++ NV++ +T
Sbjct: 74 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 133
Query: 547 AVPHLLESKGXXXXXXXXNGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 371
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 134 VVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 193
Query: 370 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 191
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG +
Sbjct: 194 PGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGET 249
Query: 190 VPVDGG 173
V V GG
Sbjct: 250 VVVGGG 255
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 103 bits (247), Expect = 8e-22
Identities = 62/198 (31%), Positives = 98/198 (49%)
Frame = -2
Query: 763 KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMN 584
K A + I ++ E ++ ++K T+D +GK++ LVNN G E+ S + ++
Sbjct: 70 KQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLR 129
Query: 583 TNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL 404
TN+ +Y+ ++ G FP + ++A V T+ +ALE
Sbjct: 130 TNLTGSFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYNLTKSLALEW 189
Query: 403 APKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLA 224
A G+R+NCV PGVI ++ S Q +F E + + R G P+EV++ + FL
Sbjct: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQ--SFFEGSFQKIPAKRIGVPEEVSSVVCFLL 247
Query: 223 SDLASNITGASVPVDGGR 170
S AS ITG SV VDGGR
Sbjct: 248 SPAASFITGQSVDVDGGR 265
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 103 bits (246), Expect = 1e-21
Identities = 62/194 (31%), Positives = 101/194 (52%), Gaps = 1/194 (0%)
Frame = -2
Query: 754 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTN 578
S I + K D E+++ K ++H G +D LV +AG+ G+ TS +D++++ N
Sbjct: 86 SVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVN 145
Query: 577 VRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAP 398
V+S L +P++ +G + YN+SK ++ TR +ALELAP
Sbjct: 146 VKSPALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAP 205
Query: 397 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 218
K +RVNCV PG+I T+ + +E + F KE H L R G+ ++ A ++FL S
Sbjct: 206 KDIRVNCVVPGIIKTDFSKVFHGNESLWKNF----KEHHQLQRIGESEDCAGIVSFLCSP 261
Query: 217 LASNITGASVPVDG 176
AS + G ++ V G
Sbjct: 262 DASYVNGENIAVAG 275
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 103 bits (246), Expect = 1e-21
Identities = 62/194 (31%), Positives = 101/194 (52%), Gaps = 1/194 (0%)
Frame = -2
Query: 754 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTN 578
S I + K D E+++ K ++H G +D LV +AG+ G+ TS +D++++ N
Sbjct: 77 SVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVN 136
Query: 577 VRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAP 398
V+S L +P++ +G + YN+SK ++ TR +ALELAP
Sbjct: 137 VKSPALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAP 196
Query: 397 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 218
K +RVNCV PG+I T+ + +E + F KE H L R G+ ++ A ++FL S
Sbjct: 197 KDIRVNCVVPGIIKTDFSKVFHGNESLWKNF----KEHHQLQRIGESEDCAGIVSFLCSP 252
Query: 217 LASNITGASVPVDG 176
AS + G ++ V G
Sbjct: 253 DASYVNGENIAVAG 266
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 103 bits (246), Expect = 1e-21
Identities = 62/194 (31%), Positives = 101/194 (52%), Gaps = 1/194 (0%)
Frame = -2
Query: 754 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTN 578
S I + K D E+++ K ++H G +D LV +AG+ G+ TS +D++++ N
Sbjct: 86 SVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVN 145
Query: 577 VRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAP 398
V+S L +P++ +G + YN+SK ++ TR +ALELAP
Sbjct: 146 VKSPALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAP 205
Query: 397 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 218
K +RVNCV PG+I T+ + +E + F KE H L R G+ ++ A ++FL S
Sbjct: 206 KDIRVNCVVPGIIKTDFSKVFHGNESLWKNF----KEHHQLQRIGESEDCAGIVSFLCSP 261
Query: 217 LASNITGASVPVDG 176
AS + G ++ V G
Sbjct: 262 DASYVNGENIAVAG 275
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 103 bits (246), Expect = 1e-21
Identities = 60/186 (32%), Positives = 103/186 (55%), Gaps = 2/186 (1%)
Frame = -2
Query: 724 KESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTML 548
K D E+++ + +G +D+LV+NA + G++ + + +D+ ++ NV++ +T
Sbjct: 74 KAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKA 133
Query: 547 AVPHLLESKGXXXXXXXXNGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 371
VP + + G S PG YN+SK ++ T+ +A+ELAP+ +RVNC+
Sbjct: 134 VVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLA 193
Query: 370 PGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGAS 191
PG+I T R + +E+ E KET + R G+P++ A ++FL S+ AS ITG +
Sbjct: 194 PGLIKTSFSRMLWMDKEKE----ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGET 249
Query: 190 VPVDGG 173
V V GG
Sbjct: 250 VVVGGG 255
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 100 bits (239), Expect = 7e-21
Identities = 61/194 (31%), Positives = 101/194 (52%), Gaps = 1/194 (0%)
Frame = -2
Query: 754 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTN 578
S I + K D E+++ K ++H G +D LV +AG+ G+ TS +D++++ N
Sbjct: 86 SVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVN 145
Query: 577 VRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAP 398
V+S L +P++ +G + Y++SK ++ TR +ALELAP
Sbjct: 146 VKSPAPLLSQLLPYMENRRGAVILVSSVAAYNPVVALGVYSVSKTALLGLTRTLALELAP 205
Query: 397 KGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 218
K +RVNCV PG+I T+ + +E + F KE H L R G+ ++ A ++FL S
Sbjct: 206 KDIRVNCVVPGIIKTDFSKVFHGNESLWKNF----KEHHQLQRIGESEDCAGIVSFLCSP 261
Query: 217 LASNITGASVPVDG 176
AS + G ++ V G
Sbjct: 262 DASYVNGENIAVAG 275
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 91.9 bits (218), Expect = 2e-18
Identities = 67/208 (32%), Positives = 103/208 (49%), Gaps = 7/208 (3%)
Frame = -2
Query: 775 KDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYD 596
++ +K+ + D+TK+ I++ + +LDVL N AG + GT+ + +D
Sbjct: 44 QELEKYPGIQTRVLDVTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWD 99
Query: 595 RLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVL---AYNISKASVDQFT 425
MN NVRS+Y + +P +L K S GV+ Y+ +KA+V T
Sbjct: 100 FSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVA-SSVKGVVNRCVYSTTKAAVIGLT 158
Query: 424 RCVALELAPKGVRVNCVNPGVILT-ELQRR---GGLSEEQYAAFLERTKETHALGRPGKP 257
+ VA + +G+R NCV PG + T LQ R G EE FL+R K GR
Sbjct: 159 KSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK----TGRFATA 214
Query: 256 DEVAATIAFLASDLASNITGASVPVDGG 173
+E+A +LASD ++ +TG V +DGG
Sbjct: 215 EEIAMLCVYLASDESTYVTGNPVIIDGG 242
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 91.9 bits (218), Expect = 2e-18
Identities = 67/208 (32%), Positives = 103/208 (49%), Gaps = 7/208 (3%)
Frame = -2
Query: 775 KDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYD 596
++ +K+ + D+TK+ I++ + +LDVL N AG + GT+ + +D
Sbjct: 44 QELEKYPGIQTRVLDVTKKKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWD 99
Query: 595 RLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVL---AYNISKASVDQFT 425
MN NVRS+Y + +P +L K S GV+ Y+ +KA+V T
Sbjct: 100 FSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVA-SSVKGVVNRCVYSTTKAAVIGLT 158
Query: 424 RCVALELAPKGVRVNCVNPGVILT-ELQRR---GGLSEEQYAAFLERTKETHALGRPGKP 257
+ VA + +G+R NCV PG + T LQ R G EE FL+R K GR
Sbjct: 159 KSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK----TGRFATA 214
Query: 256 DEVAATIAFLASDLASNITGASVPVDGG 173
+E+A +LASD ++ +TG V +DGG
Sbjct: 215 EEIAMLCVYLASDESAYVTGNPVIIDGG 242
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 91.9 bits (218), Expect = 2e-18
Identities = 67/208 (32%), Positives = 103/208 (49%), Gaps = 7/208 (3%)
Frame = -2
Query: 775 KDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYD 596
++ +K+ + D+TK+ I++ + +LDVL N AG + GT+ + +D
Sbjct: 44 QELEKYPGIQTRVLDVTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWD 99
Query: 595 RLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVL---AYNISKASVDQFT 425
MN NVRS+Y + +P +L K S GV+ Y+ +KA+V T
Sbjct: 100 FSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVA-SSVKGVVNRCVYSTTKAAVIGLT 158
Query: 424 RCVALELAPKGVRVNCVNPGVILT-ELQRR---GGLSEEQYAAFLERTKETHALGRPGKP 257
+ VA + +G+R NCV PG + T LQ R G EE FL+R K GR
Sbjct: 159 KSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK----TGRFATA 214
Query: 256 DEVAATIAFLASDLASNITGASVPVDGG 173
+E+A +LASD ++ +TG V +DGG
Sbjct: 215 EEIAMLCVYLASDESAYVTGNPVIIDGG 242
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 90.6 bits (215), Expect = 6e-18
Identities = 66/208 (31%), Positives = 103/208 (49%), Gaps = 7/208 (3%)
Frame = -2
Query: 775 KDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYD 596
++ +K+ + D+TK+ I++ + +LDVL N AG + GT+ + +D
Sbjct: 44 QELEKYPGIQTRVLDVTKKKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWD 99
Query: 595 RLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVL---AYNISKASVDQFT 425
MN NVRS+Y + +P +L K S GV+ Y+ +KA+V T
Sbjct: 100 FSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVA-SSVKGVVNRCVYSTTKAAVIGLT 158
Query: 424 RCVALELAPKGVRVNCVNPGVILT-ELQRR---GGLSEEQYAAFLERTKETHALGRPGKP 257
+ +A + +G+R NCV PG + T LQ R G EE FL+R K GR
Sbjct: 159 KSLAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQK----TGRFATA 214
Query: 256 DEVAATIAFLASDLASNITGASVPVDGG 173
+E+A +LASD ++ +TG V +DGG
Sbjct: 215 EEIAMLCVYLASDESAYVTGNPVIIDGG 242
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 85.8 bits (203), Expect = 2e-16
Identities = 57/164 (34%), Positives = 89/164 (54%), Gaps = 6/164 (3%)
Frame = -2
Query: 646 GIIETGTIENTSLAQ-YDRLMNT----NVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIR 482
G+ TGT+ + A+ +RL+ T NV++ +T VP + + G
Sbjct: 80 GLSVTGTVCHVGKAEDRERLVATTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAF 139
Query: 481 S-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 305
S PG YN+SK ++ T+ +A+ELAP+ +RVNC+ PG+I T R + +E+
Sbjct: 140 SPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE--- 196
Query: 304 LERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
E KET + R G+P++ A ++FL S+ AS ITG +V V GG
Sbjct: 197 -ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 239
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 83.4 bits (197), Expect = 9e-16
Identities = 45/139 (32%), Positives = 74/139 (53%), Gaps = 1/139 (0%)
Frame = -2
Query: 754 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRLMNTN 578
S I + K D E+++ K ++H G +D LV +AG+ G+ TS +D++++ N
Sbjct: 86 SVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVN 145
Query: 577 VRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAP 398
V+S L +P++ +G + YN+SK ++ TR +ALELAP
Sbjct: 146 VKSPALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAP 205
Query: 397 KGVRVNCVNPGVILTELQR 341
K +RVNCV PG+I T+ +
Sbjct: 206 KDIRVNCVVPGIIKTDFSK 224
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 80.6 bits (190), Expect = 6e-15
Identities = 61/212 (28%), Positives = 100/212 (47%), Gaps = 1/212 (0%)
Frame = -2
Query: 805 RNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
RN+E + + D L+ + D+ KE D++ ++ H G+++ LVN AGI G
Sbjct: 34 RNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGL 91
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T ++TN+ A+ +++ + G G++ G Y+ S
Sbjct: 92 LVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSAS 151
Query: 448 KASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGR 269
K + F+R +A E+A K +RVN V PG + T++ + L E E K+ LGR
Sbjct: 152 KGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTK--DLKE-------EHLKKNIPLGR 202
Query: 268 PGKPDEVAATIAFLASDLASNITGASVPVDGG 173
G+ EVA + FL + ITG + VDGG
Sbjct: 203 FGETIEVAHAVVFLLE--SPYITGHVLVVDGG 232
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 80.6 bits (190), Expect = 6e-15
Identities = 61/212 (28%), Positives = 100/212 (47%), Gaps = 1/212 (0%)
Frame = -2
Query: 805 RNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
RN+E + + D L+ + D+ KE D++ ++ H G+++ LVN AGI G
Sbjct: 34 RNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGL 91
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T ++TN+ A+ +++ + G G++ G Y+ S
Sbjct: 92 LVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSAS 151
Query: 448 KASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGR 269
K + F+R +A E+A K +RVN V PG + T++ + L E E K+ LGR
Sbjct: 152 KGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTK--DLKE-------EHLKKNIPLGR 202
Query: 268 PGKPDEVAATIAFLASDLASNITGASVPVDGG 173
G+ EVA + FL + ITG + VDGG
Sbjct: 203 FGETIEVAHAVVFLLE--SPYITGHVLVVDGG 232
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 77.0 bits (181), Expect = 8e-14
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 2/177 (1%)
Frame = -2
Query: 697 KKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-- 524
++ + G +D+LVNNA + + +DR N+R++ ++ +A L+
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIAARGLIARGV 127
Query: 523 KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 344
G R+ Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 128 PGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMG 187
Query: 343 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+ + L R LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 188 QATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/177 (26%), Positives = 82/177 (46%), Gaps = 2/177 (1%)
Frame = -2
Query: 697 KKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-- 524
++ + G +D+LVNNA + + +DR N+R++ ++ + L+
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGV 127
Query: 523 KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 344
G R+ Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 128 PGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMG 187
Query: 343 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+ + L R LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 188 QATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/177 (26%), Positives = 82/177 (46%), Gaps = 2/177 (1%)
Frame = -2
Query: 697 KKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-- 524
++ + G +D+LVNNA + + +DR N+R++ ++ + L+
Sbjct: 67 ERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGV 126
Query: 523 KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 344
G R+ Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 127 PGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMG 186
Query: 343 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+ + L R LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 187 QATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 239
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/177 (26%), Positives = 82/177 (46%), Gaps = 2/177 (1%)
Frame = -2
Query: 697 KKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-- 524
++ + G +D+LVNNA + + +DR N+R++ ++ + L+
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGV 127
Query: 523 KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 344
G R+ Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 128 PGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMG 187
Query: 343 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+ + L R LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 188 QATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/177 (26%), Positives = 82/177 (46%), Gaps = 2/177 (1%)
Frame = -2
Query: 697 KKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-- 524
++ + G +D+LVNNA + + +DR N+R++ ++ + L+
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGV 127
Query: 523 KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 344
G R+ Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 128 PGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMG 187
Query: 343 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+ + L R LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 188 QATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/177 (26%), Positives = 82/177 (46%), Gaps = 2/177 (1%)
Frame = -2
Query: 697 KKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-- 524
++ + G +D+LVNNA + + +DR N+R++ ++ + L+
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGV 127
Query: 523 KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 344
G R+ Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 128 PGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMG 187
Query: 343 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+ + L R LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 188 QATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/177 (26%), Positives = 82/177 (46%), Gaps = 2/177 (1%)
Frame = -2
Query: 697 KKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-- 524
++ + G +D+LVNNA + + +DR N+R++ ++ + L+
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGV 127
Query: 523 KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 344
G R+ Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 128 PGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMG 187
Query: 343 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+ + L R LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 188 QATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/177 (26%), Positives = 82/177 (46%), Gaps = 2/177 (1%)
Frame = -2
Query: 697 KKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-- 524
++ + G +D+LVNNA + + +DR N+R++ ++ + L+
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGV 127
Query: 523 KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 344
G R+ Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 128 PGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMG 187
Query: 343 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+ + L R LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 188 QATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 75.4 bits (177), Expect = 2e-13
Identities = 47/177 (26%), Positives = 82/177 (46%), Gaps = 2/177 (1%)
Frame = -2
Query: 697 KKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES-- 524
++ + G +D+LVNNA + + +DR N+R++ ++ + L+
Sbjct: 68 ERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGV 127
Query: 523 KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 344
G R+ Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 128 PGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMG 187
Query: 343 RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+ + L R LG+ + + V I FL SD + TG+++PV+GG
Sbjct: 188 QATWSDPHKAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -2
Query: 664 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXN 491
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 490 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 311
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 310 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -2
Query: 664 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXN 491
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 490 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 311
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 310 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -2
Query: 664 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXN 491
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 490 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 311
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 310 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -2
Query: 664 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXN 491
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 490 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 311
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 310 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -2
Query: 664 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXN 491
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 490 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 311
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 310 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -2
Query: 664 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXN 491
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 490 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 311
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 310 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 69.3 bits (162), Expect = 2e-11
Identities = 50/166 (30%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -2
Query: 664 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXN 491
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 490 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 311
G G Y SKA V T+ A EL G+R N V PG I T + +++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPM------TQKVPQ 212
Query: 310 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 213 KVVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 258
>CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein.
Length = 157
Score = 67.7 bits (158), Expect = 5e-11
Identities = 41/103 (39%), Positives = 57/103 (55%)
Frame = -2
Query: 478 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLE 299
FP + ++A V T+ +ALE A G+R+NCV PGVI ++ S Q +F E
Sbjct: 19 FPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQ--SFFE 76
Query: 298 RTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGGR 170
+ + R G P+EV++ + FL AS ITG SV VDGGR
Sbjct: 77 GSFQKIPAKRIGVPEEVSSVVCFLLPPAASFITGQSVDVDGGR 119
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 67.3 bits (157), Expect = 6e-11
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 7/160 (4%)
Frame = -2
Query: 805 RNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 641
R V L++V + C K L + DLT E K + +G++D+LVNN G+
Sbjct: 82 RRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGM 141
Query: 640 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVL 464
+ +TSL Y +L+ N LT +PH++E K G GI S P +
Sbjct: 142 SQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSI 201
Query: 463 AYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 347
Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 202 GYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 67.3 bits (157), Expect = 6e-11
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 7/160 (4%)
Frame = -2
Query: 805 RNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 641
R V L++V + C K L + DLT E K + +G++D+LVNN G+
Sbjct: 82 RRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGM 141
Query: 640 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVL 464
+ +TSL Y +L+ N LT +PH++E K G GI S P +
Sbjct: 142 SQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSI 201
Query: 463 AYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 347
Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 202 GYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 67.3 bits (157), Expect = 6e-11
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 7/160 (4%)
Frame = -2
Query: 805 RNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 641
R V L++V + C K L + DLT E K + +G++D+LVNN G+
Sbjct: 32 RRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGM 91
Query: 640 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVL 464
+ +TSL Y +L+ N LT +PH++E K G GI S P +
Sbjct: 92 SQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSI 151
Query: 463 AYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 347
Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 152 GYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 191
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 67.3 bits (157), Expect = 6e-11
Identities = 47/160 (29%), Positives = 72/160 (45%), Gaps = 2/160 (1%)
Frame = -2
Query: 742 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 563
+T DLT I + + +G +D+LVNNAGI GTI +T++ R+M TN
Sbjct: 117 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPV 176
Query: 562 YLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 386
LT +P +++ + G G S P AY SK + F C+ E+ +
Sbjct: 177 ALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 236
Query: 385 VNCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGR 269
V ++PG I T L ++ +Y T + AL R
Sbjct: 237 VTVISPGYIHTNLSVNAITADGSRYGVMDTTTAQAEALWR 276
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 67.3 bits (157), Expect = 6e-11
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 7/160 (4%)
Frame = -2
Query: 805 RNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 641
R V L++V + C K L + DLT E K + +G++D+LVNN G+
Sbjct: 82 RRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGM 141
Query: 640 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVL 464
+ +TSL Y +L+ N LT +PH++E K G GI S P +
Sbjct: 142 SQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSI 201
Query: 463 AYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 347
Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 202 GYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 67.3 bits (157), Expect = 6e-11
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 7/160 (4%)
Frame = -2
Query: 805 RNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 641
R V L++V + C K L + DLT E K + +G++D+LVNN G+
Sbjct: 32 RRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEFGRIDILVNNGGM 91
Query: 640 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVL 464
+ +TSL Y +L+ N LT +PH++E K G GI S P +
Sbjct: 92 SQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVNSILGIISVPLSI 151
Query: 463 AYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 347
Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 152 GYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 191
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 66.5 bits (155), Expect = 1e-10
Identities = 49/166 (29%), Positives = 79/166 (47%), Gaps = 2/166 (1%)
Frame = -2
Query: 664 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXN 491
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 97 VVVSCAGITQDEFLLHMSRDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 156
Query: 490 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 311
G G Y SKA V T+ A EL G+ N V PG I T + ++
Sbjct: 157 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIPCNSVLPGFIATPMTKKVPKK----- 211
Query: 310 AFLERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
+++ E +G G P++VA +AFLAS+ + ITG SV V GG
Sbjct: 212 -VVDKITEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGG 256
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/133 (31%), Positives = 63/133 (47%), Gaps = 1/133 (0%)
Frame = -2
Query: 742 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 563
+T DLT I + + +G +D+LVNNAGI GTI +T++ R+M TN
Sbjct: 112 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPV 171
Query: 562 YLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 386
LT +P +++ + G G S P AY SK + F C+ E+ +
Sbjct: 172 ALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 231
Query: 385 VNCVNPGVILTEL 347
V ++PG I T L
Sbjct: 232 VTVISPGYIHTNL 244
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/133 (31%), Positives = 63/133 (47%), Gaps = 1/133 (0%)
Frame = -2
Query: 742 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 563
+T DLT I + + +G +D+LVNNAGI GTI +T++ R+M TN
Sbjct: 112 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPV 171
Query: 562 YLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 386
LT +P +++ + G G S P AY SK + F C+ E+ +
Sbjct: 172 ALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 231
Query: 385 VNCVNPGVILTEL 347
V ++PG I T L
Sbjct: 232 VTVISPGYIHTNL 244
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/133 (31%), Positives = 63/133 (47%), Gaps = 1/133 (0%)
Frame = -2
Query: 742 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 563
+T DLT I + + +G +D+LVNNAGI GTI +T++ R+M TN
Sbjct: 112 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPV 171
Query: 562 YLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 386
LT +P +++ + G G S P AY SK + F C+ E+ +
Sbjct: 172 ALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 231
Query: 385 VNCVNPGVILTEL 347
V ++PG I T L
Sbjct: 232 VTVISPGYIHTNL 244
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/133 (31%), Positives = 63/133 (47%), Gaps = 1/133 (0%)
Frame = -2
Query: 742 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIY 563
+T DLT I + + +G +D+LVNNAGI GTI +T++ R+M TN
Sbjct: 97 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPV 156
Query: 562 YLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 386
LT +P +++ + G G S P AY SK + F C+ E+ +
Sbjct: 157 ALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 216
Query: 385 VNCVNPGVILTEL 347
V ++PG I T L
Sbjct: 217 VTVISPGYIHTNL 229
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 64.1 bits (149), Expect = 6e-10
Identities = 40/148 (27%), Positives = 70/148 (47%), Gaps = 1/148 (0%)
Frame = -2
Query: 805 RNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
RN+E + + D L+ + D+ KE D++ ++ H G+++ LVN AGI G
Sbjct: 34 RNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGL 91
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T ++TN+ A+ +++ + G G++ G Y+ S
Sbjct: 92 LVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSAS 151
Query: 448 KASVDQFTRCVALELAPKGVRVNCVNPG 365
K + F+R +A E+A K +RVN V PG
Sbjct: 152 KGGLVGFSRALAKEVARKKIRVNVVAPG 179
>BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein.
Length = 244
Score = 62.5 bits (145), Expect = 2e-09
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 3/195 (1%)
Frame = -2
Query: 748 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 569
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 33 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 92
Query: 568 IYYLT-MLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 392
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 93 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 152
Query: 391 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 218
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 153 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 207
Query: 217 LASNITGASVPVDGG 173
LAS +TGA + DGG
Sbjct: 208 LASYVTGAVLVADGG 222
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 62.5 bits (145), Expect = 2e-09
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 3/195 (1%)
Frame = -2
Query: 748 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 569
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 568 IYYLT-MLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 392
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200
Query: 391 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 218
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 201 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255
Query: 217 LASNITGASVPVDGG 173
LAS +TGA + DGG
Sbjct: 256 LASYVTGAVLVADGG 270
>AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 62.5 bits (145), Expect = 2e-09
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 3/195 (1%)
Frame = -2
Query: 748 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 569
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 568 IYYLT-MLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 392
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200
Query: 391 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 218
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 201 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255
Query: 217 LASNITGASVPVDGG 173
LAS +TGA + DGG
Sbjct: 256 LASYVTGAVLVADGG 270
>AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 62.5 bits (145), Expect = 2e-09
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 3/195 (1%)
Frame = -2
Query: 748 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 569
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 69 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 128
Query: 568 IYYLT-MLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 392
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 129 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 188
Query: 391 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 218
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 189 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 243
Query: 217 LASNITGASVPVDGG 173
LAS +TGA + DGG
Sbjct: 244 LASYVTGAVLVADGG 258
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 62.5 bits (145), Expect = 2e-09
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 3/195 (1%)
Frame = -2
Query: 748 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 569
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 568 IYYLT-MLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 392
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200
Query: 391 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 218
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 201 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255
Query: 217 LASNITGASVPVDGG 173
LAS +TGA + DGG
Sbjct: 256 LASYVTGAVLVADGG 270
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 62.5 bits (145), Expect = 2e-09
Identities = 53/195 (27%), Positives = 89/195 (45%), Gaps = 3/195 (1%)
Frame = -2
Query: 748 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 569
L ++ D+ + + + + +G++D+L+N A S + +M+ +
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 568 IYYLT-MLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKG 392
+ ++ +L + G G R + +KA+VD TR +A+E P+
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQN 200
Query: 391 VRVNCVNPGVIL-TE-LQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLASD 218
+RVN + PG I TE L+R GG A L L R G E+A ++ +LAS
Sbjct: 201 IRVNSLAPGPISGTEGLRRLGGPQ-----ASLSTKVTASPLQRLGNKTEIAHSVLYLASP 255
Query: 217 LASNITGASVPVDGG 173
LAS +TGA + DGG
Sbjct: 256 LASYVTGAVLVADGG 270
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 61.7 bits (143), Expect = 3e-09
Identities = 33/120 (27%), Positives = 64/120 (53%), Gaps = 2/120 (1%)
Frame = -2
Query: 724 KESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTML 548
K D E+++ + +G +D+LV+NA + G++ + + +D+ ++ NV++ +T
Sbjct: 90 KAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKA 149
Query: 547 AVPHLLESKGXXXXXXXXNGIRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 371
VP + + G S PG YN+SK ++ +A+ELAP+ +RVNC++
Sbjct: 150 VVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNCLH 209
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 61.3 bits (142), Expect = 4e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 563
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 562 YLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 383
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 382 NCVNPGVILTELQRRGGLSEEQ 317
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 61.3 bits (142), Expect = 4e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 563
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 562 YLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 383
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 382 NCVNPGVILTELQRRGGLSEEQ 317
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 61.3 bits (142), Expect = 4e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 563
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 562 YLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 383
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 382 NCVNPGVILTELQRRGGLSEEQ 317
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 61.3 bits (142), Expect = 4e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 563
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 562 YLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 383
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 382 NCVNPGVILTELQRRGGLSEEQ 317
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 60.9 bits (141), Expect = 5e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 563
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRLLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 562 YLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 383
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 382 NCVNPGVILTELQRRGGLSEEQ 317
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 60.9 bits (141), Expect = 5e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Frame = -2
Query: 661 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIR 482
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 481 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 365
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 60.9 bits (141), Expect = 5e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Frame = -2
Query: 661 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIR 482
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 481 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 365
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 60.9 bits (141), Expect = 5e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Frame = -2
Query: 661 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIR 482
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 481 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 365
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 60.9 bits (141), Expect = 5e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Frame = -2
Query: 661 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIR 482
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 481 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 365
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 60.1 bits (139), Expect = 9e-09
Identities = 46/142 (32%), Positives = 64/142 (45%), Gaps = 3/142 (2%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 563
DLTK DI + ++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRFLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 562 YLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 383
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 382 NCVNPGVILTELQRRGGLSEEQ 317
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 56.0 bits (129), Expect = 2e-07
Identities = 50/203 (24%), Positives = 82/203 (40%), Gaps = 8/203 (3%)
Frame = -2
Query: 751 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 572
TL I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+
Sbjct: 58 TLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLV 109
Query: 571 SIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVAL-- 410
S+ T L + ++ + G G+ Y SK + FTR AL
Sbjct: 110 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169
Query: 409 ELAPKGVRVNCVNPGVILTELQRRGGLSEE--QYAAFLERTKETHALGRPGKPDEVAATI 236
L GVR+N + PG + T + E QY + + K+ P +A +
Sbjct: 170 NLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGL 229
Query: 235 AFLASDLASNITGASVPVDGGRH 167
L D A N + G H
Sbjct: 230 ITLIEDDALNGAIMKITTSKGIH 252
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 56.0 bits (129), Expect = 2e-07
Identities = 50/203 (24%), Positives = 82/203 (40%), Gaps = 8/203 (3%)
Frame = -2
Query: 751 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 572
TL I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+
Sbjct: 58 TLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLV 109
Query: 571 SIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVAL-- 410
S+ T L + ++ + G G+ Y SK + FTR AL
Sbjct: 110 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169
Query: 409 ELAPKGVRVNCVNPGVILTELQRRGGLSEE--QYAAFLERTKETHALGRPGKPDEVAATI 236
L GVR+N + PG + T + E QY + + K+ P +A +
Sbjct: 170 NLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGL 229
Query: 235 AFLASDLASNITGASVPVDGGRH 167
L D A N + G H
Sbjct: 230 ITLIEDDALNGAIMKITTSKGIH 252
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 56.0 bits (129), Expect = 2e-07
Identities = 50/203 (24%), Positives = 82/203 (40%), Gaps = 8/203 (3%)
Frame = -2
Query: 751 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 572
TL I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+
Sbjct: 58 TLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLV 109
Query: 571 SIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVAL-- 410
S+ T L + ++ + G G+ Y SK + FTR AL
Sbjct: 110 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169
Query: 409 ELAPKGVRVNCVNPGVILTELQRRGGLSEE--QYAAFLERTKETHALGRPGKPDEVAATI 236
L GVR+N + PG + T + E QY + + K+ P +A +
Sbjct: 170 NLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGL 229
Query: 235 AFLASDLASNITGASVPVDGGRH 167
L D A N + G H
Sbjct: 230 ITLIEDDALNGAIMKITTSKGIH 252
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 56.0 bits (129), Expect = 2e-07
Identities = 50/203 (24%), Positives = 82/203 (40%), Gaps = 8/203 (3%)
Frame = -2
Query: 751 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 572
TL I D+ + + +K +DH+G+LD+LVNNAG+ + +++ + N+
Sbjct: 58 TLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLV 109
Query: 571 SIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVAL-- 410
S+ T L + ++ + G G+ Y SK + FTR AL
Sbjct: 110 SVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAA 169
Query: 409 ELAPKGVRVNCVNPGVILTELQRRGGLSEE--QYAAFLERTKETHALGRPGKPDEVAATI 236
L GVR+N + PG + T + E QY + + K+ P +A +
Sbjct: 170 NLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGL 229
Query: 235 AFLASDLASNITGASVPVDGGRH 167
L D A N + G H
Sbjct: 230 ITLIEDDALNGAIMKITTSKGIH 252
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 5/155 (3%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
N L++ + C + + + D + DI KK G + +LVNNAG++ T
Sbjct: 69 NKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSD 128
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T Q ++ NV + ++ T +P + ++ G G S P +LAY S
Sbjct: 129 LFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSS 188
Query: 448 KASVDQFTRCVALELAP---KGVRVNCVNPGVILT 353
K + F + + ELA GV+ C+ P + T
Sbjct: 189 KFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 5/155 (3%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
N L++ + C + + + D + DI KK G + +LVNNAG++ T
Sbjct: 69 NKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSD 128
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T Q ++ NV + ++ T +P + ++ G G S P +LAY S
Sbjct: 129 LFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSS 188
Query: 448 KASVDQFTRCVALELAP---KGVRVNCVNPGVILT 353
K + F + + ELA GV+ C+ P + T
Sbjct: 189 KFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 5/155 (3%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
N L++ + C + + + D + DI KK G + +LVNNAG++ T
Sbjct: 69 NKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSD 128
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T Q ++ NV + ++ T +P + ++ G G S P +LAY S
Sbjct: 129 LFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSS 188
Query: 448 KASVDQFTRCVALELAP---KGVRVNCVNPGVILT 353
K + F + + ELA GV+ C+ P + T
Sbjct: 189 KFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 5/155 (3%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
N L++ + C + + + D + DI KK G + +LVNNAG++ T
Sbjct: 69 NKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSD 128
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T Q ++ NV + ++ T +P + ++ G G S P +LAY S
Sbjct: 129 LFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSS 188
Query: 448 KASVDQFTRCVALELAP---KGVRVNCVNPGVILT 353
K + F + + ELA GV+ C+ P + T
Sbjct: 189 KFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 5/155 (3%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
N L++ + C + + + D + DI KK G + +LVNNAG++ T
Sbjct: 69 NKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSD 128
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T Q ++ NV + ++ T +P + ++ G G S P +LAY S
Sbjct: 129 LFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSS 188
Query: 448 KASVDQFTRCVALELAP---KGVRVNCVNPGVILT 353
K + F + + ELA GV+ C+ P + T
Sbjct: 189 KFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 5/155 (3%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
N L++ + C + + + D + DI KK G + +LVNNAG++ T
Sbjct: 69 NKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSD 128
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T Q ++ NV + ++ T +P + ++ G G S P +LAY S
Sbjct: 129 LFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSS 188
Query: 448 KASVDQFTRCVALELAP---KGVRVNCVNPGVILT 353
K + F + + ELA GV+ C+ P + T
Sbjct: 189 KFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 5/155 (3%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
N L++ + C + + + D + DI KK G + +LVNNAG++ T
Sbjct: 69 NKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSD 128
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T Q ++ NV + ++ T +P + ++ G G S P +LAY S
Sbjct: 129 LFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSS 188
Query: 448 KASVDQFTRCVALELAP---KGVRVNCVNPGVILT 353
K + F + + ELA GV+ C+ P + T
Sbjct: 189 KFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/155 (25%), Positives = 68/155 (43%), Gaps = 5/155 (3%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
N L++ + C + + + D + DI KK G + +LVNNAG++ T
Sbjct: 69 NKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSD 128
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T Q ++ NV + ++ T +P + ++ G G S P +LAY S
Sbjct: 129 LFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSS 188
Query: 448 KASVDQFTRCVALELAP---KGVRVNCVNPGVILT 353
K + F + + ELA GV+ C+ P + T
Sbjct: 189 KFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 55.2 bits (127), Expect = 3e-07
Identities = 51/206 (24%), Positives = 92/206 (44%), Gaps = 11/206 (5%)
Frame = -2
Query: 805 RNVENLQKVSKDCDK--FASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 635
R V N+++++ +C + TL DL+ E DI + + +D+ +NNAG+
Sbjct: 43 RTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLAR 102
Query: 634 TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXXXXXXXXNGIRSFPGVL 464
T+ + S + + + N NV ++ T A + E G +G R P +
Sbjct: 103 PDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSV 162
Query: 463 A--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ-RRGGLSEEQYAAFLE 299
Y+ +K +V T + EL A +R C++PGV+ T+ + E+ AA E
Sbjct: 163 THFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYE 222
Query: 298 RTKETHALGRPGKPDEVAATIAFLAS 221
+ K KP++VA + ++ S
Sbjct: 223 QMKCL-------KPEDVAEAVIYVLS 241
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 55.2 bits (127), Expect = 3e-07
Identities = 51/206 (24%), Positives = 92/206 (44%), Gaps = 11/206 (5%)
Frame = -2
Query: 805 RNVENLQKVSKDCDK--FASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 635
R V N+++++ +C + TL DL+ E DI + + +D+ +NNAG+
Sbjct: 43 RTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLAR 102
Query: 634 TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXXXXXXXXNGIRSFPGVL 464
T+ + S + + + N NV ++ T A + E G +G R P +
Sbjct: 103 PDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSV 162
Query: 463 A--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ-RRGGLSEEQYAAFLE 299
Y+ +K +V T + EL A +R C++PGV+ T+ + E+ AA E
Sbjct: 163 THFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYE 222
Query: 298 RTKETHALGRPGKPDEVAATIAFLAS 221
+ K KP++VA + ++ S
Sbjct: 223 QMKCL-------KPEDVAEAVIYVLS 241
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/173 (25%), Positives = 79/173 (45%), Gaps = 2/173 (1%)
Frame = -2
Query: 748 LSITADLTKE-SDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 572
L I+ D++++ + +E +IK+ + G +D+LVN AG+ +G E+ ++ ++RLM+ N
Sbjct: 88 LCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYL 147
Query: 571 SIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPK 395
Y + + + E + G G G AY+ SK ++ + +E+ P
Sbjct: 148 GSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPY 207
Query: 394 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATI 236
V + P T G +EE LE T+ KP++VA I
Sbjct: 208 NVYITVAYPPDTDTP-----GFAEENRTKPLE-TRLISETTSVCKPEQVAKQI 254
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/173 (25%), Positives = 79/173 (45%), Gaps = 2/173 (1%)
Frame = -2
Query: 748 LSITADLTKE-SDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 572
L I+ D++++ + +E +IK+ + G +D+LVN AG+ +G E+ ++ ++RLM+ N
Sbjct: 88 LCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYL 147
Query: 571 SIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPK 395
Y + + + E + G G G AY+ SK ++ + +E+ P
Sbjct: 148 GSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPY 207
Query: 394 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATI 236
V + P T G +EE LE T+ KP++VA I
Sbjct: 208 NVYITVAYPPDTDTP-----GFAEENRTKPLE-TRLISETTSVCKPEQVAKQI 254
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/159 (28%), Positives = 78/159 (49%), Gaps = 6/159 (3%)
Frame = -2
Query: 805 RNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
RN E LQ V+KD D + T I AD + +I I++ + + +LVNN G+
Sbjct: 99 RNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-VGILVNNVGVFYP 157
Query: 631 GTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVL 464
T L++ D+L +N N+ + + + +P ++E KG + + P +
Sbjct: 158 YPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLA 216
Query: 463 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 217 AFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/173 (25%), Positives = 79/173 (45%), Gaps = 2/173 (1%)
Frame = -2
Query: 748 LSITADLTKE-SDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVR 572
L I+ D++++ + +E +IK+ + G +D+LVN AG+ +G E+ ++ ++RLM+ N
Sbjct: 88 LCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYL 147
Query: 571 SIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPK 395
Y + + + E + G G G AY+ SK ++ + +E+ P
Sbjct: 148 GSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPY 207
Query: 394 GVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATI 236
V + P T G +EE LE T+ KP++VA I
Sbjct: 208 NVYITVAYPPDTDTP-----GFAEENRTKPLE-TRLISETTSVCKPEQVAKQI 254
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/159 (28%), Positives = 78/159 (49%), Gaps = 6/159 (3%)
Frame = -2
Query: 805 RNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
RN E LQ V+KD D + T I AD + +I I++ + + +LVNN G+
Sbjct: 78 RNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-VGILVNNVGVFYP 136
Query: 631 GTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVL 464
T L++ D+L +N N+ + + + +P ++E KG + + P +
Sbjct: 137 YPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLA 195
Query: 463 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 196 AFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 234
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/159 (28%), Positives = 78/159 (49%), Gaps = 6/159 (3%)
Frame = -2
Query: 805 RNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
RN E LQ V+KD D + T I AD + +I I++ + + +LVNN G+
Sbjct: 99 RNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-VGILVNNVGVFYP 157
Query: 631 GTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVL 464
T L++ D+L +N N+ + + + +P ++E KG + + P +
Sbjct: 158 YPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLA 216
Query: 463 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 217 AFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 54.8 bits (126), Expect = 3e-07
Identities = 45/159 (28%), Positives = 78/159 (49%), Gaps = 6/159 (3%)
Frame = -2
Query: 805 RNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
RN E LQ V+KD D + T I AD + +I I++ + + +LVNN G+
Sbjct: 78 RNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-VGILVNNVGVFYP 136
Query: 631 GTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVL 464
T L++ D+L +N N+ + + + +P ++E KG + + P +
Sbjct: 137 YPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLA 195
Query: 463 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 196 AFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 234
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/198 (24%), Positives = 84/198 (42%), Gaps = 3/198 (1%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 566
+I D+ ++ + + I G ++++NNA E S + + + +
Sbjct: 113 AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGT 172
Query: 565 YYLTMLAVPHLLES-KGXXXXXXXXNGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKG 392
++T+ L+++ KG + G + + S KA V+ ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 391 VRVNCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 215
+R N + PG I T +G S + F + GR G +E+A AFL SD
Sbjct: 233 MRFNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDY 288
Query: 214 ASNITGASVPVDGGRHAM 161
AS I GA + DGG +
Sbjct: 289 ASWINGAVIKFDGGEEVL 306
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/198 (24%), Positives = 84/198 (42%), Gaps = 3/198 (1%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 566
+I D+ ++ + + I G ++++NNA E S + + + +
Sbjct: 113 AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGT 172
Query: 565 YYLTMLAVPHLLES-KGXXXXXXXXNGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKG 392
++T+ L+++ KG + G + + S KA V+ ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 391 VRVNCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 215
+R N + PG I T +G S + F + GR G +E+A AFL SD
Sbjct: 233 MRFNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDY 288
Query: 214 ASNITGASVPVDGGRHAM 161
AS I GA + DGG +
Sbjct: 289 ASWINGAVIKFDGGEEVL 306
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 53.6 bits (123), Expect = 8e-07
Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 6/159 (3%)
Frame = -2
Query: 805 RNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
RN E LQ V+KD D + T I AD + +I I++ + + +LVNN G+
Sbjct: 99 RNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-VGILVNNVGVFYP 157
Query: 631 GTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVL 464
T L++ D+L +N N+ + + + +P ++E KG + + P +
Sbjct: 158 YPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLA 216
Query: 463 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
A++ S+A +D F+R + E A KG+ V + P + T +
Sbjct: 217 AFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/198 (24%), Positives = 84/198 (42%), Gaps = 3/198 (1%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 566
+I D+ ++ + + I G ++++NNA E S + + + +
Sbjct: 113 AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGT 172
Query: 565 YYLTMLAVPHLLES-KGXXXXXXXXNGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKG 392
++T+ L+++ KG + G + + S KA V+ ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 391 VRVNCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 215
+R N + PG I T +G S + F + GR G +E+A AFL SD
Sbjct: 233 MRFNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDY 288
Query: 214 ASNITGASVPVDGGRHAM 161
AS I GA + DGG +
Sbjct: 289 ASWINGAVIKFDGGEEVL 306
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/198 (24%), Positives = 84/198 (42%), Gaps = 3/198 (1%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 566
+I D+ ++ + + I G ++++NNA E S + + + +
Sbjct: 113 AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGT 172
Query: 565 YYLTMLAVPHLLES-KGXXXXXXXXNGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKG 392
++T+ L+++ KG + G + + S KA V+ ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 391 VRVNCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 215
+R N + PG I T +G S + F + GR G +E+A AFL SD
Sbjct: 233 MRFNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDY 288
Query: 214 ASNITGASVPVDGGRHAM 161
AS I GA + DGG +
Sbjct: 289 ASWINGAVIKFDGGEEVL 306
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 53.6 bits (123), Expect = 8e-07
Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 6/159 (3%)
Frame = -2
Query: 805 RNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
RN E LQ V+KD D + T I AD + +I I++ + + +LVNN G+
Sbjct: 99 RNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-VGILVNNVGVFYP 157
Query: 631 GTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVL 464
T L++ D+L +N N+ + + + +P ++E KG + + P +
Sbjct: 158 YPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLA 216
Query: 463 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
A++ S+A +D F+R + E A KG+ V + P + T +
Sbjct: 217 AFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 53.6 bits (123), Expect = 8e-07
Identities = 48/198 (24%), Positives = 84/198 (42%), Gaps = 3/198 (1%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 566
+I D+ ++ + + I G ++++NNA E S + + + +
Sbjct: 113 AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGT 172
Query: 565 YYLTMLAVPHLLES-KGXXXXXXXXNGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKG 392
++T+ L+++ KG + G + + S KA V+ ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 391 VRVNCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 215
+R N + PG I T +G S + F + GR G +E+A AFL SD
Sbjct: 233 MRFNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDY 288
Query: 214 ASNITGASVPVDGGRHAM 161
AS I GA + DGG +
Sbjct: 289 ASWINGAVIKFDGGEEVL 306
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = -2
Query: 709 EKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL 530
EK++K +D +G++DV+VNNAGI+ + S +D + ++R + +T A H+
Sbjct: 80 EKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMK 139
Query: 529 ESK-GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 368
+ K G +GI G Y+ +K + +A+E + N + P
Sbjct: 140 KQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 53.2 bits (122), Expect = 1e-06
Identities = 39/155 (25%), Positives = 67/155 (43%), Gaps = 5/155 (3%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGT 626
N L++ + C + + + D + DI K G + +LVNNAG++ T
Sbjct: 69 NKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKNCKAEIGDVSILVNNAGVVYTSD 128
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXNGIRSFPGVLAYNIS 449
+ T Q ++ NV + ++ T +P + ++ G G S P +LAY S
Sbjct: 129 LFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSS 188
Query: 448 KASVDQFTRCVALELAP---KGVRVNCVNPGVILT 353
K + F + + ELA GV+ C+ P + T
Sbjct: 189 KFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = -2
Query: 709 EKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL 530
EK++K +D +G++DV+VNNAGI+ + S +D + ++R + +T A H+
Sbjct: 80 EKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMK 139
Query: 529 ESK-GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 368
+ K G +GI G Y+ +K + +A+E + N + P
Sbjct: 140 KQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/115 (26%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = -2
Query: 709 EKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLL 530
EK++K +D +G++DV+VNNAGI+ + S +D + ++R + +T A H+
Sbjct: 80 EKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMK 139
Query: 529 ESK-GXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 368
+ K G +GI G Y+ +K + +A+E + N + P
Sbjct: 140 KQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 52.8 bits (121), Expect = 1e-06
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 6/152 (3%)
Frame = -2
Query: 805 RNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
RN E LQ V+KD D + T I AD + +I I++ + + +LVNN G+
Sbjct: 99 RNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-VGILVNNVGVFYP 157
Query: 631 GTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVL 464
T L++ D+L +N N+ + + + +P ++E KG + + P +
Sbjct: 158 YPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLA 216
Query: 463 AYNISKASVDQFTRCVALELAPKGVRVNCVNP 368
A++ SKA +D F+R + E A KG+ V + P
Sbjct: 217 AFSASKAYLDHFSRALQYEYASKGIFVQSLIP 248
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/172 (23%), Positives = 78/172 (45%), Gaps = 9/172 (5%)
Frame = -2
Query: 808 GRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKLDVLVNNA--GI 641
GR+++ L+ V+++ + + D ++ES++ + ++ + G+LDVLVNNA G+
Sbjct: 38 GRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGV 97
Query: 640 IETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSF 476
N T + +D + N +R Y+ ++ ++ + G +
Sbjct: 98 QTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQY 157
Query: 475 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 320
+ Y + KA+ D+ A EL GV + PG++ TEL + EE
Sbjct: 158 MFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEE 209
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/172 (23%), Positives = 78/172 (45%), Gaps = 9/172 (5%)
Frame = -2
Query: 808 GRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKLDVLVNNA--GI 641
GR+++ L+ V+++ + + D ++ES++ + ++ + G+LDVLVNNA G+
Sbjct: 38 GRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGV 97
Query: 640 IETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSF 476
N T + +D + N +R Y+ ++ ++ + G +
Sbjct: 98 QTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQY 157
Query: 475 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 320
+ Y + KA+ D+ A EL GV + PG++ TEL + EE
Sbjct: 158 MFNVLYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEE 209
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/172 (23%), Positives = 78/172 (45%), Gaps = 9/172 (5%)
Frame = -2
Query: 808 GRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKLDVLVNNA--GI 641
GR+++ L+ V+++ + + D ++ES++ + ++ + G+LDVLVNNA G+
Sbjct: 38 GRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGV 97
Query: 640 IETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSF 476
N T + +D + N +R Y+ ++ ++ + G +
Sbjct: 98 QTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQY 157
Query: 475 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 320
+ Y + KA+ D+ A EL GV + PG++ TEL + EE
Sbjct: 158 MFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEE 209
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/172 (23%), Positives = 78/172 (45%), Gaps = 9/172 (5%)
Frame = -2
Query: 808 GRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKLDVLVNNA--GI 641
GR+++ L+ V+++ + + D ++ES++ + ++ + G+LDVLVNNA G+
Sbjct: 38 GRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGV 97
Query: 640 IETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSF 476
N T + +D + N +R Y+ ++ ++ + G +
Sbjct: 98 QTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQY 157
Query: 475 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEE 320
+ Y + KA+ D+ A EL GV + PG++ TEL + EE
Sbjct: 158 MFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEE 209
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 52.4 bits (120), Expect = 2e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Frame = -2
Query: 748 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 569
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 568 IYYLTMLAVPHLLESK 521
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 52.4 bits (120), Expect = 2e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Frame = -2
Query: 748 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 569
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 568 IYYLTMLAVPHLLESK 521
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 52.4 bits (120), Expect = 2e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Frame = -2
Query: 748 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 569
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 568 IYYLTMLAVPHLLESK 521
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 51.2 bits (117), Expect = 4e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 574 RSIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVL---AYNISKASVDQFTRCV 416
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 415 ALELAPKGVRVNCVNPGVILTEL 347
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 51.2 bits (117), Expect = 4e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 574 RSIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVL---AYNISKASVDQFTRCV 416
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 415 ALELAPKGVRVNCVNPGVILTEL 347
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 51.2 bits (117), Expect = 4e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 574 RSIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVL---AYNISKASVDQFTRCV 416
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 415 ALELAPKGVRVNCVNPGVILTEL 347
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 51.2 bits (117), Expect = 4e-06
Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 4/156 (2%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDHYGKLDVLVNNAGIIET 632
N +++ + C S L + D+TK I+ K + G L ++NNAG++
Sbjct: 117 NGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGF 173
Query: 631 GTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYN 455
T E + Y + M N +T +P L +SKG G + +Y
Sbjct: 174 PTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYG 233
Query: 454 ISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 234 SSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 51.2 bits (117), Expect = 4e-06
Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 4/156 (2%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDHYGKLDVLVNNAGIIET 632
N +++ + C S L + D+TK I+ K + G L ++NNAG++
Sbjct: 117 NGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGF 173
Query: 631 GTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYN 455
T E + Y + M N +T +P L +SKG G + +Y
Sbjct: 174 PTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYG 233
Query: 454 ISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 234 SSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 51.2 bits (117), Expect = 4e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 574 RSIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVL---AYNISKASVDQFTRCV 416
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 415 ALELAPKGVRVNCVNPGVILTEL 347
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 51.2 bits (117), Expect = 4e-06
Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 4/156 (2%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDHYGKLDVLVNNAGIIET 632
N +++ + C S L + D+TK I+ K + G L ++NNAG++
Sbjct: 117 NGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGF 173
Query: 631 GTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYN 455
T E + Y + M N +T +P L +SKG G + +Y
Sbjct: 174 PTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYG 233
Query: 454 ISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 234 SSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 51.2 bits (117), Expect = 4e-06
Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 4/156 (2%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDHYGKLDVLVNNAGIIET 632
N +++ + C S L + D+TK I+ K + G L ++NNAG++
Sbjct: 117 NGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGF 173
Query: 631 GTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYN 455
T E + Y + M N +T +P L +SKG G + +Y
Sbjct: 174 PTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYG 233
Query: 454 ISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 234 SSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 51.2 bits (117), Expect = 4e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 574 RSIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVL---AYNISKASVDQFTRCV 416
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 415 ALELAPKGVRVNCVNPGVILTEL 347
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 51.2 bits (117), Expect = 4e-06
Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 4/156 (2%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDHYGKLDVLVNNAGIIET 632
N +++ + C S L + D+TK I+ K + G L ++NNAG++
Sbjct: 117 NGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGF 173
Query: 631 GTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYN 455
T E + Y + M N +T +P L +SKG G + +Y
Sbjct: 174 PTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYG 233
Query: 454 ISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 234 SSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 51.2 bits (117), Expect = 4e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 13 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 72
Query: 574 RSIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVL---AYNISKASVDQFTRCV 416
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 73 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 132
Query: 415 ALELAPKGVRVNCVNPGVILTEL 347
A +LAP G+RV + PG+ T L
Sbjct: 133 ARDLAPIGIRVMTIAPGLFGTPL 155
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 51.2 bits (117), Expect = 4e-06
Identities = 42/156 (26%), Positives = 69/156 (44%), Gaps = 4/156 (2%)
Frame = -2
Query: 802 NVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDHYGKLDVLVNNAGIIET 632
N +++ + C S L + D+TK I+ K + G L ++NNAG++
Sbjct: 117 NGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGF 173
Query: 631 GTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYN 455
T E + Y + M N +T +P L +SKG G + +Y
Sbjct: 174 PTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYG 233
Query: 454 ISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 234 SSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 51.2 bits (117), Expect = 4e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 574 RSIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVL---AYNISKASVDQFTRCV 416
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 415 ALELAPKGVRVNCVNPGVILTEL 347
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 51.2 bits (117), Expect = 4e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 574 RSIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVL---AYNISKASVDQFTRCV 416
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 415 ALELAPKGVRVNCVNPGVILTEL 347
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 51.2 bits (117), Expect = 4e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 574 RSIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVL---AYNISKASVDQFTRCV 416
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 415 ALELAPKGVRVNCVNPGVILTEL 347
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 50.8 bits (116), Expect = 6e-06
Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 1/112 (0%)
Frame = -2
Query: 676 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 500
G++DVLVNNAG+ G +E SLA + +TN L +P + + G
Sbjct: 82 GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVIS 141
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 344
G++ Y SK +++ F +A++L + ++ V PG ++TE +
Sbjct: 142 SVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLVEPGPVVTEFE 193
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 49.6 bits (113), Expect = 1e-05
Identities = 46/194 (23%), Positives = 82/194 (42%), Gaps = 3/194 (1%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 566
+I D+ ++ + + I G ++++NNA E S + + + +
Sbjct: 113 AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGT 172
Query: 565 YYLTMLAVPHLLES-KGXXXXXXXXNGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKG 392
++T+ L+++ KG + G + + S KA V+ ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 391 VRVNCVNPGVILTELQRRGGLSE-EQYAAFLERTKETHALGRPGKPDEVAATIAFLASDL 215
+R N + PG I T +G S + F + GR G +E+A AFL S
Sbjct: 233 MRFNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSGY 288
Query: 214 ASNITGASVPVDGG 173
AS + GA + DGG
Sbjct: 289 ASWVNGAVIKFDGG 302
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 47.6 bits (108), Expect = 5e-05
Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 1/99 (1%)
Frame = -2
Query: 601 YDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRS-FPGVLAYNISKASVDQFT 425
+D+ ++ NV++ +T VP + + G S PG YN+SK ++
Sbjct: 10 WDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLN 69
Query: 424 RCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 308
+A+ELAP+ +RVNC++ + L+ L G L E + A
Sbjct: 70 NTLAIELAPRNIRVNCLH--LDLSRLASAGWLGEPEDCA 106
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 46.8 bits (106), Expect = 9e-05
Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 5/157 (3%)
Frame = -2
Query: 805 RNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
R+ E LQKV C + AS I + + E+ + + G LD+L+ N +
Sbjct: 66 RSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTS 125
Query: 631 GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNI 452
+ + + + M N S LT+ A+P L +S G G ++P V AY+
Sbjct: 126 LNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSA 185
Query: 451 SKASVDQFTRCVALELAPKGVRVN---CVNPGVILTE 350
SK ++D F + E + V V+ CV G+I TE
Sbjct: 186 SKFALDGFFSSIRKEYSVSRVNVSITLCV-LGLIDTE 221
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 46.8 bits (106), Expect = 9e-05
Identities = 43/174 (24%), Positives = 77/174 (44%), Gaps = 3/174 (1%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGK--LDVLVNNAGI-IETGT 626
E QK+ +D T + D+TK I+ + D G+ L LVNNAG+ + +G
Sbjct: 60 EGSQKLQRDTSYRLQTTLL--DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGP 117
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISK 446
E + + +++N N+ + +T+ +P + ++G G + G Y +SK
Sbjct: 118 NEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG-GYCVSK 176
Query: 445 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 284
V+ F+ + EL GV+V + PG T + + L + +ET
Sbjct: 177 FGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQET 230
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 46.8 bits (106), Expect = 9e-05
Identities = 43/174 (24%), Positives = 77/174 (44%), Gaps = 3/174 (1%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGK--LDVLVNNAGI-IETGT 626
E QK+ +D T + D+TK I+ + D G+ L LVNNAG+ + +G
Sbjct: 60 EGSQKLQRDTSYRLQTTLL--DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGP 117
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISK 446
E + + +++N N+ + +T+ +P + ++G G + G Y +SK
Sbjct: 118 NEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG-GYCVSK 176
Query: 445 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 284
V+ F+ + EL GV+V + PG T + + L + +ET
Sbjct: 177 FGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQET 230
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 46.8 bits (106), Expect = 9e-05
Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 5/157 (3%)
Frame = -2
Query: 805 RNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
R+ E LQKV C + AS I + + E+ + + G LD+L+ N +
Sbjct: 66 RSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTS 125
Query: 631 GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNI 452
+ + + + M N S LT+ A+P L +S G G ++P V AY+
Sbjct: 126 LNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSA 185
Query: 451 SKASVDQFTRCVALELAPKGVRVN---CVNPGVILTE 350
SK ++D F + E + V V+ CV G+I TE
Sbjct: 186 SKFALDGFFSSIRKEYSVSRVNVSITLCV-LGLIDTE 221
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 46.8 bits (106), Expect = 9e-05
Identities = 43/174 (24%), Positives = 77/174 (44%), Gaps = 3/174 (1%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGK--LDVLVNNAGI-IETGT 626
E QK+ +D T + D+TK I+ + D G+ L LVNNAG+ + +G
Sbjct: 60 EGSQKLQRDTSYRLQTTLL--DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGP 117
Query: 625 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISK 446
E + + +++N N+ + +T+ +P + ++G G + G Y +SK
Sbjct: 118 NEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG-GYCVSK 176
Query: 445 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 284
V+ F+ + EL GV+V + PG T + + L + +ET
Sbjct: 177 FGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQET 230
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 46.8 bits (106), Expect = 9e-05
Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 5/157 (3%)
Frame = -2
Query: 805 RNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
R+ E LQKV C + AS I + + E+ + + G LD+L+ N +
Sbjct: 66 RSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTS 125
Query: 631 GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNI 452
+ + + + M N S LT+ A+P L +S G G ++P V AY+
Sbjct: 126 LNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSA 185
Query: 451 SKASVDQFTRCVALELAPKGVRVN---CVNPGVILTE 350
SK ++D F + E + V V+ CV G+I TE
Sbjct: 186 SKFALDGFFSSIRKEYSVSRVNVSITLCV-LGLIDTE 221
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 46.8 bits (106), Expect = 9e-05
Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 5/157 (3%)
Frame = -2
Query: 805 RNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
R+ E LQKV C + AS I + + E+ + + G LD+L+ N +
Sbjct: 66 RSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTS 125
Query: 631 GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNI 452
+ + + + M N S LT+ A+P L +S G G ++P V AY+
Sbjct: 126 LNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSA 185
Query: 451 SKASVDQFTRCVALELAPKGVRVN---CVNPGVILTE 350
SK ++D F + E + V V+ CV G+I TE
Sbjct: 186 SKFALDGFFSSIRKEYSVSRVNVSITLCV-LGLIDTE 221
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 46.8 bits (106), Expect = 9e-05
Identities = 44/157 (28%), Positives = 70/157 (44%), Gaps = 5/157 (3%)
Frame = -2
Query: 805 RNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET 632
R+ E LQKV C + AS I + + E+ + + G LD+L+ N +
Sbjct: 66 RSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTS 125
Query: 631 GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNI 452
+ + + + M N S LT+ A+P L +S G G ++P V AY+
Sbjct: 126 LNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSA 185
Query: 451 SKASVDQFTRCVALELAPKGVRVN---CVNPGVILTE 350
SK ++D F + E + V V+ CV G+I TE
Sbjct: 186 SKFALDGFFSSIRKEYSVSRVNVSITLCV-LGLIDTE 221
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/85 (29%), Positives = 44/85 (51%)
Frame = -2
Query: 775 KDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYD 596
++ +K+ + D+TK+ I++ + +LDVL N AG + GT+ + +D
Sbjct: 44 QELEKYPGIQTRVLDVTKKKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWD 99
Query: 595 RLMNTNVRSIYYLTMLAVPHLLESK 521
MN NVRS+Y + +P +L K
Sbjct: 100 FSMNLNVRSMYLMIKAFLPKMLAQK 124
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/85 (29%), Positives = 44/85 (51%)
Frame = -2
Query: 775 KDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYD 596
++ +K+ + D+TK+ I++ + +LDVL N AG + GT+ + +D
Sbjct: 44 QELEKYPGIQTRVLDVTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWD 99
Query: 595 RLMNTNVRSIYYLTMLAVPHLLESK 521
MN NVRS+Y + +P +L K
Sbjct: 100 FSMNLNVRSMYLMIKAFLPKMLAQK 124
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 3/134 (2%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 575
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 574 RSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPK 395
+ +T+ +P + ++G G +F V Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 394 GVRVNCVNPGVILT 353
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 46.0 bits (104), Expect = 2e-04
Identities = 42/139 (30%), Positives = 59/139 (42%), Gaps = 3/139 (2%)
Frame = -2
Query: 790 LQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLDVLV-NNAGIIETGTIE 620
LQKV +C K + I AD+ E +++ +D G LD LV N+ G GT
Sbjct: 66 LQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRA 125
Query: 619 NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ A LM N S LT A+P L +SKG G Y+ +K +
Sbjct: 126 RSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFA 184
Query: 439 VDQFTRCVALELAPKGVRV 383
+D F + EL + V V
Sbjct: 185 LDGFFGSLRRELDVQDVNV 203
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 46.0 bits (104), Expect = 2e-04
Identities = 42/139 (30%), Positives = 59/139 (42%), Gaps = 3/139 (2%)
Frame = -2
Query: 790 LQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLDVLV-NNAGIIETGTIE 620
LQKV +C K + I AD+ E +++ +D G LD LV N+ G GT
Sbjct: 66 LQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRA 125
Query: 619 NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ A LM N S LT A+P L +SKG G Y+ +K +
Sbjct: 126 RSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFA 184
Query: 439 VDQFTRCVALELAPKGVRV 383
+D F + EL + V V
Sbjct: 185 LDGFFGSLRRELDVQDVNV 203
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 46.0 bits (104), Expect = 2e-04
Identities = 25/85 (29%), Positives = 44/85 (51%)
Frame = -2
Query: 775 KDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYD 596
++ +K+ + D+TK+ I++ + +LDVL N AG + GT+ + +D
Sbjct: 44 QELEKYPGIQTRVLDVTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWD 99
Query: 595 RLMNTNVRSIYYLTMLAVPHLLESK 521
MN NVRS+Y + +P +L K
Sbjct: 100 FSMNLNVRSMYLMIKAFLPKMLAQK 124
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 3/134 (2%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 575
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 574 RSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPK 395
+ +T+ +P + ++G G +F V Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 394 GVRVNCVNPGVILT 353
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 46.0 bits (104), Expect = 2e-04
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 3/134 (2%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 575
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 574 RSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPK 395
+ +T+ +P + ++G G +F V Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 394 GVRVNCVNPGVILT 353
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha
hydroxysteroid dehydrogenase protein.
Length = 317
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 3/134 (2%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYG--KLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNV 575
++T D+TK I + +H G +L LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRRLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 574 RSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPK 395
+ +T+ +P + ++G +G F Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGKNCQCLQHSGKSCFL-CRGYCVSKYGVEAFSDILRREIQHF 197
Query: 394 GVRVNCVNPGVILT 353
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 44.8 bits (101), Expect = 4e-04
Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 1/174 (0%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIE 620
E+LQ+V+ + +TL D K ++ + G L LVNNAG+ G
Sbjct: 66 EDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAGIIGPTP 122
Query: 619 NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ + R++N N +T+ +P L +++G G + G Y +SK
Sbjct: 123 WLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GYCVSKFG 181
Query: 439 VDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 278
++ F+ + ++A G+RV+ V PG T + L + A + T A
Sbjct: 182 LEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 44.8 bits (101), Expect = 4e-04
Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 1/174 (0%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIE 620
E+LQ+V+ + +TL D K ++ + G L LVNNAG+ G
Sbjct: 66 EDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAGIIGPTP 122
Query: 619 NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ + R++N N +T+ +P L +++G G + G Y +SK
Sbjct: 123 WLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GYCVSKFG 181
Query: 439 VDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 278
++ F+ + ++A G+RV+ V PG T + L + A + T A
Sbjct: 182 LEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 44.8 bits (101), Expect = 4e-04
Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 1/174 (0%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIE 620
E+LQ+V+ + +TL D K ++ + G L LVNNAG+ G
Sbjct: 66 EDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAGIIGPTP 122
Query: 619 NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ + R++N N +T+ +P L +++G G + G Y +SK
Sbjct: 123 WLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GYCVSKFG 181
Query: 439 VDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 278
++ F+ + ++A G+RV+ V PG T + L + A + T A
Sbjct: 182 LEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 44.4 bits (100), Expect = 5e-04
Identities = 18/46 (39%), Positives = 27/46 (58%)
Frame = -2
Query: 751 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT 614
TL I D+ + + +K +DH+G+LD+LVNNAG+ E T
Sbjct: 58 TLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNKKNWEKT 103
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 44.4 bits (100), Expect = 5e-04
Identities = 18/46 (39%), Positives = 27/46 (58%)
Frame = -2
Query: 751 TLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT 614
TL I D+ + + +K +DH+G+LD+LVNNAG+ E T
Sbjct: 58 TLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKT 103
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 44.0 bits (99), Expect = 7e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Frame = -2
Query: 739 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 560
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 559 LTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL--APK-G 392
T +P +LE + G G+ S GV Y SK V F ++ EL A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 391 VRVNCVNPGVILTELQR 341
++ V P ++ T + R
Sbjct: 236 IKTTLVCPYLVDTGMFR 252
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 44.0 bits (99), Expect = 7e-04
Identities = 42/181 (23%), Positives = 76/181 (41%), Gaps = 15/181 (8%)
Frame = -2
Query: 805 RNVENLQKVSKDCDKFASTLSITA---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 635
R++E + +KD + A DL I + K I+ ++D+L+NNAG++
Sbjct: 70 RDMEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMR 129
Query: 634 TG--TIENTSLAQYD----------RLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXN 491
T E+ Q+ L+ +++ ++ + L G
Sbjct: 130 CPHWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNW 189
Query: 490 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 311
R + AY SK ++ FT+ ++ L GV VN ++PGV TEL R G+ ++
Sbjct: 190 QTRKYNTKAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTELGRHTGIHGSTFS 249
Query: 310 A 308
+
Sbjct: 250 S 250
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 44.0 bits (99), Expect = 7e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Frame = -2
Query: 739 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 560
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 559 LTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL--APK-G 392
T +P +LE + G G+ S GV Y SK V F ++ EL A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 391 VRVNCVNPGVILTELQR 341
++ V P ++ T + R
Sbjct: 236 IKTTLVCPYLVDTGMFR 252
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 44.0 bits (99), Expect = 7e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Frame = -2
Query: 739 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 560
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 559 LTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL--APK-G 392
T +P +LE + G G+ S GV Y SK V F ++ EL A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 391 VRVNCVNPGVILTELQR 341
++ V P ++ T + R
Sbjct: 236 IKTTLVCPYLVDTGMFR 252
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 43.6 bits (98), Expect = 9e-04
Identities = 37/135 (27%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = -2
Query: 745 SITADLTKESDIEKI---IKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTN 578
++T D+TK + +K+ + G L LVNNAGI + T E + + +++ N
Sbjct: 79 TVTLDVTKTESVAAAAQWVKECVRDKG-LWGLVNNAGISLPTAPNELLTKQDFVTILDVN 137
Query: 577 VRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAP 398
+ + +T+ +P + +++G G S G Y ISK V+ F+ + EL+
Sbjct: 138 LLGVIDVTLSLLPLVRKARGRVVNVSSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELSY 196
Query: 397 KGVRVNCVNPGVILT 353
GV+V + PG T
Sbjct: 197 FGVKVAMIEPGYFKT 211
>BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 13
(all-trans/9-cis) protein.
Length = 260
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/154 (24%), Positives = 66/154 (42%), Gaps = 12/154 (7%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG--TIENTSLAQYD----------RL 590
DL I + K I+ ++D+L+NNAG++ T E+ Q+ L
Sbjct: 26 DLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNL 85
Query: 589 MNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVAL 410
+ +++ ++ + L G R + AY SK ++ FT+ ++
Sbjct: 86 LLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSR 145
Query: 409 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 308
L GV VN ++PGV TEL R G+ +++
Sbjct: 146 RLQGSGVTVNALHPGVARTELGRHTGIHGSTFSS 179
>CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein.
Length = 181
Score = 42.7 bits (96), Expect = 0.002
Identities = 42/162 (25%), Positives = 73/162 (45%), Gaps = 8/162 (4%)
Frame = -2
Query: 682 HYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXX 512
H G +D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 9 HSG-VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHI 67
Query: 511 XXXXXXNGIRSFPGVLA--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ 344
+G R P + Y+ +K +V T + EL A +R C++PGV+ T+
Sbjct: 68 ININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFA 127
Query: 343 -RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 221
+ E+ AA E+ K KP++VA + ++ S
Sbjct: 128 FKLHDKDPEKAAATYEQMKCL-------KPEDVAEAVIYVLS 162
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 42.7 bits (96), Expect = 0.002
Identities = 42/181 (23%), Positives = 75/181 (41%), Gaps = 15/181 (8%)
Frame = -2
Query: 805 RNVENLQKVSKDCDKFASTLSITA---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 635
R++E + +KD + A DL I K I+ ++D+L+NNAG++
Sbjct: 70 RDMEKCEAAAKDIRGETLNHHVNARHLDLASLKSIRVFAAKIIEEEERVDILINNAGVMR 129
Query: 634 TG--TIENTSLAQYD----------RLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXN 491
T E+ Q+ L+ +++ ++ + L G
Sbjct: 130 CPHWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNW 189
Query: 490 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 311
R + AY SK ++ FT+ ++ L GV VN ++PGV TEL R G+ ++
Sbjct: 190 QTRKYNTKAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTELGRHTGIHGSTFS 249
Query: 310 A 308
+
Sbjct: 250 S 250
>AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22543 fis, clone HSI00212. ).
Length = 181
Score = 42.7 bits (96), Expect = 0.002
Identities = 42/162 (25%), Positives = 73/162 (45%), Gaps = 8/162 (4%)
Frame = -2
Query: 682 HYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXX 512
H G +D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 9 HSG-VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHI 67
Query: 511 XXXXXXNGIRSFPGVLA--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ 344
+G R P + Y+ +K +V T + EL A +R C++PGV+ T+
Sbjct: 68 ININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFA 127
Query: 343 -RRGGLSEEQYAAFLERTKETHALGRPGKPDEVAATIAFLAS 221
+ E+ AA E+ K KP++VA + ++ S
Sbjct: 128 FKLHDKDPEKAAATYEQMKCL-------KPEDVAEAVIYVLS 162
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 42.7 bits (96), Expect = 0.002
Identities = 40/136 (29%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Frame = -2
Query: 745 SITADLTKESDIEKI---IKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRL--MNT 581
++T D+TK + +K+ + G L LVNNAGI T N L + D L ++
Sbjct: 79 TVTLDVTKTESVAAAAQWVKECVRDKG-LWGLVNNAGI-SLPTAPNELLTKQDLLTILDV 136
Query: 580 NVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELA 401
N+ + +T+ +P + ++G G S G Y ISK V+ F+ + EL+
Sbjct: 137 NLLGVIDVTLNLLPLVRRARGRVVNVFSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELS 195
Query: 400 PKGVRVNCVNPGVILT 353
GV+V + PG T
Sbjct: 196 YFGVKVAMIEPGYFKT 211
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 41.5 bits (93), Expect = 0.003
Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 2/152 (1%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN 617
E ++++ +C F D+ ++ + K + G + +LVNNA ++ ++ +
Sbjct: 81 EEIRQMGTECHYFI------CDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMD 134
Query: 616 TSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ + + N ++ T +P +LE G + + PG + Y SKAS
Sbjct: 135 SDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKAS 194
Query: 439 VDQFTRCVALELAP-KGVRVNCVNPGVILTEL 347
F + L L GV V P TE+
Sbjct: 195 AFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 41.5 bits (93), Expect = 0.003
Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 2/152 (1%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN 617
E ++++ +C F D+ ++ + K + G + +LVNNA ++ ++ +
Sbjct: 81 EEIRQMGTECHYFI------CDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMD 134
Query: 616 TSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ + + N ++ T +P +LE G + + PG + Y SKAS
Sbjct: 135 SDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKAS 194
Query: 439 VDQFTRCVALELAP-KGVRVNCVNPGVILTEL 347
F + L L GV V P TE+
Sbjct: 195 AFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 41.5 bits (93), Expect = 0.003
Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 2/152 (1%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN 617
E ++++ +C F D+ ++ + K + G + +LVNNA ++ ++ +
Sbjct: 81 EEIRQMGTECHYFI------CDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMD 134
Query: 616 TSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ + + N ++ T +P +LE G + + PG + Y SKAS
Sbjct: 135 SDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKAS 194
Query: 439 VDQFTRCVALELAP-KGVRVNCVNPGVILTEL 347
F + L L GV V P TE+
Sbjct: 195 AFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 41.5 bits (93), Expect = 0.003
Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 2/152 (1%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN 617
E ++++ +C F D+ ++ + K + G + +LVNNA ++ ++ +
Sbjct: 81 EEIRQMGTECHYFI------CDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMD 134
Query: 616 TSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ + + N ++ T +P +LE G + + PG + Y SKAS
Sbjct: 135 SDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKAS 194
Query: 439 VDQFTRCVALELAP-KGVRVNCVNPGVILTEL 347
F + L L GV V P TE+
Sbjct: 195 AFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 41.5 bits (93), Expect = 0.003
Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 2/152 (1%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN 617
E ++++ +C F D+ ++ + K + G + +LVNNA ++ ++ +
Sbjct: 81 EEIRQMGTECHYFI------CDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMD 134
Query: 616 TSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ + + N ++ T +P +LE G + + PG + Y SKAS
Sbjct: 135 SDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKAS 194
Query: 439 VDQFTRCVALELAP-KGVRVNCVNPGVILTEL 347
F + L L GV V P TE+
Sbjct: 195 AFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 41.5 bits (93), Expect = 0.003
Identities = 33/152 (21%), Positives = 62/152 (40%), Gaps = 2/152 (1%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIEN 617
E ++++ +C F D+ ++ + K + G + +LVNNA ++ ++ +
Sbjct: 81 EEIRQMGTECHYFI------CDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMD 134
Query: 616 TSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ + + N ++ T +P +LE G + + PG + Y SKAS
Sbjct: 135 SDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKAS 194
Query: 439 VDQFTRCVALELAP-KGVRVNCVNPGVILTEL 347
F + L L GV V P TE+
Sbjct: 195 AFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 41.1 bits (92), Expect = 0.005
Identities = 42/174 (24%), Positives = 72/174 (41%), Gaps = 1/174 (0%)
Frame = -2
Query: 796 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIET-GTIE 620
E+LQ V+ F +TL D K ++ + G L LVNNAG+ G
Sbjct: 66 EDLQGVASS--GFNTTLLDITDPQSFQQAAKWVEMHVKEAG-LFGLVNNAGVAGIIGPTP 122
Query: 619 NTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKAS 440
+ + R++N N +T+ +P L +++G G + G Y +SK
Sbjct: 123 WLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GYCVSKFG 181
Query: 439 VDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 278
++ F+ + ++A G+R + V PG T + L + A + T A
Sbjct: 182 LEAFSDSLRRDVAHFGIRESIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 147
Score = 41.1 bits (92), Expect = 0.005
Identities = 30/131 (22%), Positives = 54/131 (41%), Gaps = 2/131 (1%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 554
D+ ++ + K + G + +LVNNA ++ ++ ++ + + N ++ T
Sbjct: 11 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 70
Query: 553 MLAVPHLLE-SKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVN 380
+P +LE G + + PG + Y SKAS F + L L GV
Sbjct: 71 KAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSAT 130
Query: 379 CVNPGVILTEL 347
V P TE+
Sbjct: 131 TVLPFHTSTEM 141
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 581
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 580 NVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELA 401
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 400 PKGVRVNCVNPGVILTEL 347
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 581
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 580 NVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELA 401
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 400 PKGVRVNCVNPGVILTEL 347
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 581
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 580 NVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELA 401
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 400 PKGVRVNCVNPGVILTEL 347
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 581
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 580 NVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELA 401
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 400 PKGVRVNCVNPGVILTEL 347
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 581
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 580 NVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELA 401
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 400 PKGVRVNCVNPGVILTEL 347
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 581
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 580 NVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELA 401
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 400 PKGVRVNCVNPGVILTEL 347
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 581
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 580 NVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELA 401
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 400 PKGVRVNCVNPGVILTEL 347
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 581
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 580 NVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELA 401
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 400 PKGVRVNCVNPGVILTEL 347
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = -2
Query: 745 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 581
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 580 NVRSIYYLTMLAVPHLLESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELA 401
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 400 PKGVRVNCVNPGVILTEL 347
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 40.3 bits (90), Expect = 0.008
Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 13/129 (10%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 574 RSIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVL---AYNISKASVDQFTRCV 416
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 415 ALELAPKGV 389
A +LAP G+
Sbjct: 183 ARDLAPIGL 191
>DQ338571-1|ABC61321.1| 160|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B2 isoform protein.
Length = 160
Score = 40.3 bits (90), Expect = 0.008
Identities = 20/43 (46%), Positives = 28/43 (65%)
Frame = -2
Query: 301 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
E KET + R G+P++ A ++FL S+ AS ITG +V V GG
Sbjct: 113 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 155
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 40.3 bits (90), Expect = 0.008
Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 13/129 (10%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 574 RSIYYLTMLAVPHLLESK----GXXXXXXXXNGIRSFPGVL---AYNISKASVDQFTRCV 416
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 415 ALELAPKGV 389
A +LAP G+
Sbjct: 183 ARDLAPIGL 191
>AY943857-1|AAX49568.1| 57|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase A1 like protein 1 protein.
Length = 57
Score = 40.3 bits (90), Expect = 0.008
Identities = 20/43 (46%), Positives = 28/43 (65%)
Frame = -2
Query: 301 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
E KET + R G+P++ A ++FL S+ AS ITG +V V GG
Sbjct: 10 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 52
>AY616183-1|AAT70758.1| 91|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform-like protein 1
protein.
Length = 91
Score = 40.3 bits (90), Expect = 0.008
Identities = 20/43 (46%), Positives = 28/43 (65%)
Frame = -2
Query: 301 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
E KET + R G+P++ A ++FL S+ AS ITG +V V GG
Sbjct: 44 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 86
>AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol
dehydrogenase short isoform protein.
Length = 174
Score = 40.3 bits (90), Expect = 0.008
Identities = 20/43 (46%), Positives = 28/43 (65%)
Frame = -2
Query: 301 ERTKETHALGRPGKPDEVAATIAFLASDLASNITGASVPVDGG 173
E KET + R G+P++ A ++FL S+ AS ITG +V V GG
Sbjct: 127 ESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 169
>AY268353-1|AAP42287.1| 199|Homo sapiens short-chain
dehydrogenase/reductase 10c protein.
Length = 199
Score = 36.7 bits (81), Expect = 0.099
Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 1/110 (0%)
Frame = -2
Query: 709 EKIIKKTIDHYGKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL 533
E +++ +D G LD LV N+ G GT + A LM N S LT A+P L
Sbjct: 8 ESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSL 66
Query: 532 LESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 383
+SKG G Y+ +K ++D F + EL + V V
Sbjct: 67 TDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 116
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = -2
Query: 676 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 500
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 338
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = -2
Query: 676 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 500
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 338
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = -2
Query: 676 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 500
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 338
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = -2
Query: 676 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 500
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 338
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = -2
Query: 676 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 500
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 338
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = -2
Query: 676 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 500
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 338
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = -2
Query: 676 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 500
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 338
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 14
(all-trans/9-cis/11-cis) protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.92
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 13/144 (9%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 554
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 553 MLAVPHLLES-------------KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVA 413
L + L S K N +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 412 LELAPKGVRVNCVNPGVILTELQR 341
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.92
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 13/144 (9%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 554
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 553 MLAVPHLLES-------------KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVA 413
L + L S K N +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 412 LELAPKGVRVNCVNPGVILTELQR 341
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.92
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 13/144 (9%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 554
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 553 MLAVPHLLES-------------KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVA 413
L + L S K N +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 412 LELAPKGVRVNCVNPGVILTELQR 341
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.92
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 13/144 (9%)
Frame = -2
Query: 733 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 554
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 553 MLAVPHLLES-------------KGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVA 413
L + L S K N +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 412 LELAPKGVRVNCVNPGVILTELQR 341
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 32.7 bits (71), Expect = 1.6
Identities = 26/133 (19%), Positives = 53/133 (39%), Gaps = 4/133 (3%)
Frame = -2
Query: 739 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 560
T D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 96 TCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLW 155
Query: 559 LTMLAVPHLL-ESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL---APKG 392
+P ++ G G+ G+ Y SK + F V +E KG
Sbjct: 156 TYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKG 215
Query: 391 VRVNCVNPGVILT 353
++ V P I T
Sbjct: 216 IKTTIVCPFFIKT 228
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 32.7 bits (71), Expect = 1.6
Identities = 26/133 (19%), Positives = 53/133 (39%), Gaps = 4/133 (3%)
Frame = -2
Query: 739 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 560
T D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 96 TCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLW 155
Query: 559 LTMLAVPHLL-ESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL---APKG 392
+P ++ G G+ G+ Y SK + F V +E KG
Sbjct: 156 TYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKG 215
Query: 391 VRVNCVNPGVILT 353
++ V P I T
Sbjct: 216 IKTTIVCPFFIKT 228
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 32.7 bits (71), Expect = 1.6
Identities = 26/133 (19%), Positives = 53/133 (39%), Gaps = 4/133 (3%)
Frame = -2
Query: 739 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 560
T D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 96 TCDCSQKEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLW 155
Query: 559 LTMLAVPHLL-ESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL---APKG 392
+P ++ G G+ G+ Y SK + F V +E KG
Sbjct: 156 TYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKG 215
Query: 391 VRVNCVNPGVILT 353
++ V P I T
Sbjct: 216 IKTTIVCPFFIKT 228
>Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 169
Score = 31.5 bits (68), Expect = 3.7
Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Frame = -2
Query: 736 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 575
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 574 RSIYYLTML 548
+ + L
Sbjct: 123 MGTFNVIRL 131
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 31.5 bits (68), Expect = 3.7
Identities = 19/45 (42%), Positives = 24/45 (53%)
Frame = -2
Query: 463 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 329
AY SK + FTR +A L GV V+PGV+ +EL R L
Sbjct: 199 AYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSL 243
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 31.5 bits (68), Expect = 3.7
Identities = 24/128 (18%), Positives = 51/128 (39%), Gaps = 4/128 (3%)
Frame = -2
Query: 739 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 560
T D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 96 TCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLW 155
Query: 559 LTMLAVPHLL-ESKGXXXXXXXXNGIRSFPGVLAYNISKASVDQFTRCVALEL---APKG 392
+P ++ G G+ G+ Y SK + F V +E KG
Sbjct: 156 TYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKG 215
Query: 391 VRVNCVNP 368
++ V P
Sbjct: 216 IKTTIVCP 223
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 31.5 bits (68), Expect = 3.7
Identities = 19/45 (42%), Positives = 24/45 (53%)
Frame = -2
Query: 463 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 329
AY SK + FTR +A L GV V+PGV+ +EL R L
Sbjct: 199 AYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSL 243
>AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 166
Score = 31.1 bits (67), Expect = 4.9
Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Frame = -2
Query: 754 STLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE-TGTIENTSLAQYDRL 590
S I + K D E+++ K ++H G +D LV +AG+ G+ TS +D++
Sbjct: 103 SVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKV 158
>BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein.
Length = 181
Score = 30.7 bits (66), Expect = 6.5
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Frame = -2
Query: 676 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 500
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 1 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 59
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 383
G Y+ +K ++D F + EL + V V
Sbjct: 60 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 98
>BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein.
Length = 181
Score = 30.7 bits (66), Expect = 6.5
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Frame = -2
Query: 676 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 500
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 1 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 59
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 383
G Y+ +K ++D F + EL + V V
Sbjct: 60 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 98
>AY313896-1|AAP83168.1| 234|Homo sapiens short-chain
dehydrogenase/reductase 10g protein.
Length = 234
Score = 30.7 bits (66), Expect = 6.5
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Frame = -2
Query: 676 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 500
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 25 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 83
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 383
G Y+ +K ++D F + EL + V V
Sbjct: 84 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 122
>AY268351-1|AAP42285.1| 205|Homo sapiens short-chain
dehydrogenase/reductase 10a protein.
Length = 205
Score = 30.7 bits (66), Expect = 6.5
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Frame = -2
Query: 676 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 500
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 25 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 83
Query: 499 XXNGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 383
G Y+ +K ++D F + EL + V V
Sbjct: 84 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 122
>AF240697-1|AAF82747.1| 172|Homo sapiens retinol dehydrogenase
homolog isoform-2 protein.
Length = 172
Score = 30.7 bits (66), Expect = 6.5
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = -2
Query: 460 YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 347
Y SK +V+ F + +L GV V+C+ PG+ T L
Sbjct: 29 YTPSKYAVEGFNDSLRRDLKAFGVHVSCIEPGLFKTNL 66
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 119,015,706
Number of Sequences: 237096
Number of extensions: 2722098
Number of successful extensions: 6239
Number of sequences better than 10.0: 212
Number of HSP's better than 10.0 without gapping: 5628
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6144
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10036353240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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