Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmmt16i07
(863 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 130 5e-30
BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family... 130 8e-30
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 122 2e-27
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 121 4e-27
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 121 4e-27
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 121 4e-27
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 121 4e-27
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 118 3e-26
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 118 3e-26
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 118 3e-26
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 118 3e-26
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 118 3e-26
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 118 3e-26
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 118 3e-26
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 118 3e-26
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 118 3e-26
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 105 2e-22
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 105 2e-22
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 104 4e-22
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 99 2e-20
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 98 3e-20
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 98 3e-20
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 98 3e-20
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 98 3e-20
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 95 2e-19
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 90 8e-18
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 90 8e-18
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 88 4e-17
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 88 4e-17
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 88 4e-17
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 88 4e-17
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 87 8e-17
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 87 8e-17
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 87 8e-17
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 87 8e-17
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 87 8e-17
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 87 8e-17
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 87 8e-17
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 87 8e-17
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 87 8e-17
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 87 8e-17
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 87 8e-17
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 87 8e-17
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 87 1e-16
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 85 3e-16
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 85 3e-16
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 85 3e-16
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 85 3e-16
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 85 4e-16
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 85 4e-16
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 84 5e-16
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 84 7e-16
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 84 7e-16
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 82 2e-15
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 82 2e-15
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 82 2e-15
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 82 2e-15
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 82 3e-15
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 82 3e-15
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 82 3e-15
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 82 3e-15
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 77 6e-14
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 77 6e-14
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 77 6e-14
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 77 6e-14
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 77 6e-14
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 77 6e-14
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 77 6e-14
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 77 1e-13
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 76 1e-13
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 75 3e-13
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 75 3e-13
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 75 3e-13
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 75 3e-13
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 75 3e-13
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 75 3e-13
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 75 3e-13
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 75 3e-13
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 75 3e-13
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 75 3e-13
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 75 3e-13
BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 75 3e-13
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 75 3e-13
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 75 3e-13
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 3e-13
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 75 3e-13
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 75 3e-13
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 75 3e-13
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 75 3e-13
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 75 3e-13
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 75 3e-13
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 75 3e-13
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 75 3e-13
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 75 3e-13
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 75 3e-13
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 75 3e-13
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 75 4e-13
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 75 4e-13
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 75 4e-13
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 75 4e-13
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 75 4e-13
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 75 4e-13
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 75 4e-13
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 75 4e-13
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 75 4e-13
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 75 4e-13
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 75 4e-13
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 75 4e-13
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 75 4e-13
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 75 4e-13
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 75 4e-13
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 74 6e-13
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 74 6e-13
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 73 1e-12
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 73 1e-12
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 73 1e-12
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 73 1e-12
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 73 1e-12
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 73 1e-12
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 73 2e-12
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 73 2e-12
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 73 2e-12
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 72 2e-12
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 71 5e-12
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 7e-12
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 69 3e-11
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 69 3e-11
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 68 4e-11
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 68 4e-11
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 68 4e-11
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 4e-11
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 68 4e-11
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 68 4e-11
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 68 4e-11
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 68 4e-11
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 68 4e-11
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 68 4e-11
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 68 4e-11
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 68 4e-11
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 68 4e-11
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 68 4e-11
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 68 5e-11
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 68 5e-11
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 66 2e-10
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 66 2e-10
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 66 2e-10
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 66 2e-10
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 66 2e-10
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 66 2e-10
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 66 2e-10
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 66 2e-10
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 66 2e-10
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 65 3e-10
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 65 4e-10
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 65 4e-10
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 65 4e-10
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 65 4e-10
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 65 4e-10
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 65 4e-10
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 65 4e-10
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 65 4e-10
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 65 4e-10
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 65 4e-10
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 65 4e-10
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 65 4e-10
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 65 4e-10
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 65 4e-10
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 65 4e-10
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 65 4e-10
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 65 4e-10
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 65 4e-10
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 65 4e-10
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 65 4e-10
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 65 4e-10
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 65 4e-10
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 64 5e-10
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 64 5e-10
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 64 5e-10
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 64 5e-10
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 64 6e-10
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 64 6e-10
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 64 6e-10
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 64 6e-10
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 64 6e-10
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 64 6e-10
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 64 6e-10
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 64 6e-10
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 64 6e-10
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 64 6e-10
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 64 6e-10
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 64 6e-10
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 64 6e-10
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 64 6e-10
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 64 6e-10
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 64 6e-10
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 64 6e-10
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 64 8e-10
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 63 1e-09
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 63 1e-09
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 63 1e-09
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 62 2e-09
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 62 2e-09
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 61 4e-09
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 61 6e-09
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 61 6e-09
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 61 6e-09
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 61 6e-09
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 61 6e-09
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 61 6e-09
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 60 1e-08
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 60 1e-08
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 60 1e-08
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 60 1e-08
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 60 1e-08
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 60 1e-08
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 60 1e-08
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 60 1e-08
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 60 1e-08
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 60 1e-08
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 60 1e-08
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 60 1e-08
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 59 2e-08
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 59 2e-08
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 59 2e-08
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 59 2e-08
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 59 2e-08
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 59 2e-08
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 59 2e-08
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 59 2e-08
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 59 2e-08
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 59 2e-08
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 59 2e-08
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 59 2e-08
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 59 2e-08
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 59 2e-08
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 59 2e-08
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 59 2e-08
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 59 2e-08
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 59 2e-08
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 59 2e-08
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 59 2e-08
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 59 2e-08
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 58 4e-08
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 58 5e-08
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 58 5e-08
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 58 5e-08
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 58 5e-08
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 58 5e-08
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 58 5e-08
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 58 5e-08
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 58 5e-08
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 57 7e-08
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 57 7e-08
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 57 1e-07
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 57 1e-07
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 57 1e-07
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 56 1e-07
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 56 1e-07
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 56 1e-07
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 56 1e-07
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 56 1e-07
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 56 1e-07
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 56 1e-07
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 56 1e-07
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 56 1e-07
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 56 1e-07
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 56 1e-07
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 56 2e-07
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 56 2e-07
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 56 2e-07
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 56 2e-07
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 56 2e-07
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 56 2e-07
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 56 2e-07
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 56 2e-07
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 56 2e-07
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 56 2e-07
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 56 2e-07
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 56 2e-07
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 56 2e-07
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 56 2e-07
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 56 2e-07
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 56 2e-07
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 56 2e-07
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 55 3e-07
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 55 3e-07
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 55 3e-07
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 55 3e-07
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 54 5e-07
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 54 5e-07
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 54 5e-07
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 54 5e-07
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 54 5e-07
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 54 5e-07
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 54 5e-07
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 54 5e-07
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 54 5e-07
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 54 5e-07
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 54 5e-07
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 54 7e-07
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 54 7e-07
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 54 7e-07
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 54 7e-07
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 54 9e-07
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 53 1e-06
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 53 1e-06
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 53 1e-06
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 53 1e-06
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 53 1e-06
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 53 1e-06
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 53 1e-06
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 53 2e-06
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 52 2e-06
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 52 3e-06
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 52 3e-06
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 52 4e-06
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 52 4e-06
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 52 4e-06
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 52 4e-06
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 52 4e-06
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 52 4e-06
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 51 5e-06
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 51 5e-06
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 51 5e-06
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 51 5e-06
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 51 5e-06
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 51 5e-06
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 51 5e-06
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 51 5e-06
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 51 5e-06
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 51 6e-06
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 51 6e-06
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 50 8e-06
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 49 2e-05
BC128535-1|AAI28536.1| 143|Homo sapiens CYP21A2 protein protein. 49 2e-05
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 48 3e-05
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 48 3e-05
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 48 3e-05
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 48 6e-05
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 47 8e-05
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 46 2e-04
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 46 2e-04
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 46 2e-04
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 46 2e-04
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 45 3e-04
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 45 3e-04
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 45 3e-04
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 45 3e-04
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 45 3e-04
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 45 3e-04
X56088-1|CAA39568.1| 504|Homo sapiens cholesterol 7-alpha-hydr... 45 4e-04
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 45 4e-04
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 45 4e-04
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 45 4e-04
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 45 4e-04
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 45 4e-04
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 45 4e-04
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 45 4e-04
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 45 4e-04
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 45 4e-04
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 45 4e-04
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 45 4e-04
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 45 4e-04
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 45 4e-04
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 44 5e-04
M93133-1|AAA58435.1| 504|Homo sapiens cholesterol 7-alpha hydro... 44 0.001
BC112184-1|AAI12185.1| 504|Homo sapiens cytochrome P450, family... 44 0.001
BC101777-1|AAI01778.1| 504|Homo sapiens cytochrome P450, family... 44 0.001
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 43 0.002
S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 42 0.002
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 42 0.004
AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 42 0.004
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 41 0.005
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 41 0.007
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 41 0.007
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 41 0.007
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 41 0.007
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 41 0.007
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 40 0.009
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 40 0.012
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 38 0.036
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 38 0.036
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 38 0.036
X58899-1|CAA41703.1| 368|Homo sapiens steroid 21-monooxygenase ... 38 0.036
X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase ... 38 0.036
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 38 0.036
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 38 0.036
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 37 0.082
AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 37 0.082
AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein. 36 0.14
AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein. 36 0.14
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 36 0.25
BC067444-1|AAH67444.1| 501|Homo sapiens cytochrome P450, family... 35 0.33
BC067442-1|AAH67442.1| 501|Homo sapiens cytochrome P450, family... 35 0.33
AF090320-1|AAD19877.1| 501|Homo sapiens sterol 12-alpha-hydroxy... 35 0.33
AF090318-1|AAC63037.1| 462|Homo sapiens sterol 12-alpha hydroxy... 35 0.33
U77845-1|AAB52993.1| 469|Homo sapiens hTRIP protein. 34 0.77
BC067441-1|AAH67441.1| 501|Homo sapiens cytochrome P450, family... 34 0.77
BC067434-1|AAH67434.1| 501|Homo sapiens cytochrome P450, family... 34 0.77
BC019283-1|AAH19283.1| 469|Homo sapiens TRAF interacting protei... 33 1.3
BC000310-1|AAH00310.1| 469|Homo sapiens TRAF interacting protei... 33 1.3
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 33 1.8
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 32 3.1
AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens ... 32 3.1
BC127003-1|AAI27004.1| 868|Homo sapiens zinc finger protein 28 ... 31 5.4
BC127002-1|AAI27003.1| 868|Homo sapiens zinc finger protein 28 ... 31 5.4
AF507045-1|AAM28892.1| 868|Homo sapiens zinc finger protein 28 ... 31 5.4
AB037852-1|BAA92669.1| 891|Homo sapiens KIAA1431 protein protein. 31 5.4
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 31 7.2
BC056258-1|AAH56258.1| 359|Homo sapiens CYP19A1 protein protein. 31 7.2
BC020767-1|AAH20767.1| 360|Homo sapiens Unknown (protein for IM... 31 7.2
AL772284-4|CAI41521.1| 1093|Homo sapiens novel protein protein. 31 7.2
AB033036-1|BAA86524.1| 1115|Homo sapiens KIAA1210 protein protein. 31 7.2
Z82203-1|CAI42695.1| 802|Homo sapiens oligophrenin 1 protein. 30 9.5
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 30 9.5
BC059393-1|AAH59393.1| 311|Homo sapiens OPHN1 protein protein. 30 9.5
AL672138-1|CAI41508.1| 802|Homo sapiens oligophrenin 1 protein. 30 9.5
AL158201-3|CAI40982.1| 802|Homo sapiens oligophrenin 1 protein. 30 9.5
AL157700-1|CAD18899.2| 802|Homo sapiens oligophrenin 1 protein. 30 9.5
AJ248245-1|CAB96181.1| 802|Homo sapiens oligophrenin-1 protein. 30 9.5
AJ001189-1|CAA04579.1| 802|Homo sapiens oligophrenin 1 protein. 30 9.5
AF042838-1|AAC97073.1| 1495|Homo sapiens MEK kinase 1 protein. 30 9.5
AB102656-1|BAC81125.1| 802|Homo sapiens oligophrenin 1 protein. 30 9.5
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 130 bits (315), Expect = 5e-30
Identities = 76/196 (38%), Positives = 115/196 (58%), Gaps = 11/196 (5%)
Frame = -2
Query: 646 LEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS 467
L + L + E YA + ++ML+AGVDTTS T+S T+YL+A + + QQ + E++ G+R
Sbjct: 161 LSQALTLQEIYANV--TEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERH 218
Query: 466 Y-----------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSM 320
+RA +KE +R+ PV+ GN R T ++ I GY IP+ +A H S
Sbjct: 219 VPTAADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSY 278
Query: 319 MEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSK 140
++ +PR EF PERWL K D F + PFG GVRSCIGRRIAELE+ + +
Sbjct: 279 QDENFPRAKEFRPERWL-RKGD---LDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQ 334
Query: 139 IVENFQVEWSGSSPRV 92
++++F+++ S + V
Sbjct: 335 LLQHFEIKTSSQTNAV 350
>BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family
27, subfamily C, polypeptide 1 protein.
Length = 372
Score = 130 bits (313), Expect = 8e-30
Identities = 75/196 (38%), Positives = 115/196 (58%), Gaps = 11/196 (5%)
Frame = -2
Query: 646 LEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS 467
L + L + E YA + ++ML+AGVDTTS T+S T+Y++A + + QQ + E++ G+R
Sbjct: 161 LSQALTLQEIYANV--TEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGERH 218
Query: 466 Y-----------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSM 320
+RA +KE +R+ PV+ GN R T ++ I GY IP+ +A H S
Sbjct: 219 VPTAADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSY 278
Query: 319 MEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSK 140
++ +PR EF PERWL K D F + PFG GVRSCIGRRIAELE+ + +
Sbjct: 279 QDENFPRAKEFRPERWL-RKGD---LDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQ 334
Query: 139 IVENFQVEWSGSSPRV 92
++++F+++ S + V
Sbjct: 335 LLQHFEIKTSSQTNAV 350
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 122 bits (293), Expect = 2e-27
Identities = 65/170 (38%), Positives = 99/170 (58%), Gaps = 11/170 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS----------KN-GKRSYLRACI 449
++L+AGVDTTSNT++ LY ++ + + Q+ L EEV+ K+ L+A +
Sbjct: 331 ELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQVPQHKDFAHMPLLKAVL 390
Query: 448 KEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWL 269
KE +R+ PVV N R KE + G+ P+N F H +S + P F P RWL
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYEVSRDPTAFSEPESFQPHRWL 450
Query: 268 TNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
N S P HPF + PFG+GVR+C+GRRIAELE++ L+++++ ++V
Sbjct: 451 RN-SQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKV 499
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 121 bits (291), Expect = 4e-27
Identities = 65/170 (38%), Positives = 99/170 (58%), Gaps = 11/170 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS----------KN-GKRSYLRACI 449
++L+AGVDTTSNT++ LY ++ + + Q+ L EEV+ K+ L+A +
Sbjct: 330 ELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVL 389
Query: 448 KEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWL 269
KE +R+ PVV N R KE + G+ P+N F H +S + P F P RWL
Sbjct: 390 KETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 449
Query: 268 TNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
N S P HPF + PFG+GVR+C+GRRIAELE++ L+++++ ++V
Sbjct: 450 RN-SQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKV 498
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 121 bits (291), Expect = 4e-27
Identities = 65/170 (38%), Positives = 99/170 (58%), Gaps = 11/170 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS----------KN-GKRSYLRACI 449
++L+AGVDTTSNT++ LY ++ + + Q+ L EEV+ K+ L+A +
Sbjct: 331 ELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVL 390
Query: 448 KEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWL 269
KE +R+ PVV N R KE + G+ P+N F H +S + P F P RWL
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 450
Query: 268 TNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
N S P HPF + PFG+GVR+C+GRRIAELE++ L+++++ ++V
Sbjct: 451 RN-SQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKV 499
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 121 bits (291), Expect = 4e-27
Identities = 65/170 (38%), Positives = 99/170 (58%), Gaps = 11/170 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS----------KN-GKRSYLRACI 449
++L+AGVDTTSNT++ LY ++ + + Q+ L EEV+ K+ L+A +
Sbjct: 331 ELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVL 390
Query: 448 KEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWL 269
KE +R+ PVV N R KE + G+ P+N F H +S + P F P RWL
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 450
Query: 268 TNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
N S P HPF + PFG+GVR+C+GRRIAELE++ L+++++ ++V
Sbjct: 451 RN-SQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKV 499
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 121 bits (291), Expect = 4e-27
Identities = 65/170 (38%), Positives = 99/170 (58%), Gaps = 11/170 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS----------KN-GKRSYLRACI 449
++L+AGVDTTSNT++ LY ++ + + Q+ L EEV+ K+ L+A +
Sbjct: 331 ELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVL 390
Query: 448 KEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWL 269
KE +R+ PVV N R KE + G+ P+N F H +S + P F P RWL
Sbjct: 391 KETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWL 450
Query: 268 TNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
N S P HPF + PFG+GVR+C+GRRIAELE++ L+++++ ++V
Sbjct: 451 RN-SQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKV 499
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 118 bits (284), Expect = 3e-26
Identities = 66/174 (37%), Positives = 99/174 (56%), Gaps = 13/174 (7%)
Frame = -2
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS--KNGKRSY-----------LR 458
+++L+AGVDT SNT+S LY ++ + + Q L E+ + G +Y L+
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 457 ACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPE 278
A +KE +R+ PVV GN R K+ ++ Y IP+N + H S +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 277 RWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
RWL P HPFA+ PFGFG RSC+GRR+AELE++ L++I+ +F+V+
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQ 479
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 118 bits (284), Expect = 3e-26
Identities = 66/174 (37%), Positives = 99/174 (56%), Gaps = 13/174 (7%)
Frame = -2
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS--KNGKRSY-----------LR 458
+++L+AGVDT SNT+S LY ++ + + Q L E+ + G +Y L+
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 457 ACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPE 278
A +KE +R+ PVV GN R K+ ++ Y IP+N + H S +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 277 RWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
RWL P HPFA+ PFGFG RSC+GRR+AELE++ L++I+ +F+V+
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQ 479
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 118 bits (284), Expect = 3e-26
Identities = 66/174 (37%), Positives = 99/174 (56%), Gaps = 13/174 (7%)
Frame = -2
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS--KNGKRSY-----------LR 458
+++L+AGVDT SNT+S LY ++ + + Q L E+ + G +Y L+
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 457 ACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPE 278
A +KE +R+ PVV GN R K+ ++ Y IP+N + H S +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 277 RWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
RWL P HPFA+ PFGFG RSC+GRR+AELE++ L++I+ +F+V+
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQ 479
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 118 bits (284), Expect = 3e-26
Identities = 66/174 (37%), Positives = 99/174 (56%), Gaps = 13/174 (7%)
Frame = -2
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS--KNGKRSY-----------LR 458
+++L+AGVDT SNT+S LY ++ + + Q L E+ + G +Y L+
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 457 ACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPE 278
A +KE +R+ PVV GN R K+ ++ Y IP+N + H S +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 277 RWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
RWL P HPFA+ PFGFG RSC+GRR+AELE++ L++I+ +F+V+
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQ 479
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 118 bits (284), Expect = 3e-26
Identities = 66/174 (37%), Positives = 99/174 (56%), Gaps = 13/174 (7%)
Frame = -2
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS--KNGKRSY-----------LR 458
+++L+AGVDT SNT+S LY ++ + + Q L E+ + G +Y L+
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 457 ACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPE 278
A +KE +R+ PVV GN R K+ ++ Y IP+N + H S +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 277 RWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
RWL P HPFA+ PFGFG RSC+GRR+AELE++ L++I+ +F+V+
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQ 479
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 118 bits (284), Expect = 3e-26
Identities = 66/174 (37%), Positives = 99/174 (56%), Gaps = 13/174 (7%)
Frame = -2
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS--KNGKRSY-----------LR 458
+++L+AGVDT SNT+S LY ++ + + Q L E+ + G +Y L+
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 457 ACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPE 278
A +KE +R+ PVV GN R K+ ++ Y IP+N + H S +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 277 RWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
RWL P HPFA+ PFGFG RSC+GRR+AELE++ L++I+ +F+V+
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQ 479
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 118 bits (284), Expect = 3e-26
Identities = 66/174 (37%), Positives = 99/174 (56%), Gaps = 13/174 (7%)
Frame = -2
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS--KNGKRSY-----------LR 458
+++L+AGVDT SNT+S LY ++ + + Q L E+ + G +Y L+
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 457 ACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPE 278
A +KE +R+ PVV GN R K+ ++ Y IP+N + H S +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 277 RWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
RWL P HPFA+ PFGFG RSC+GRR+AELE++ L++I+ +F+V+
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQ 479
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 118 bits (284), Expect = 3e-26
Identities = 66/174 (37%), Positives = 99/174 (56%), Gaps = 13/174 (7%)
Frame = -2
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS--KNGKRSY-----------LR 458
+++L+AGVDT SNT+S LY ++ + + Q L E+ + G +Y L+
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 457 ACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPE 278
A +KE +R+ PVV GN R K+ ++ Y IP+N + H S +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 277 RWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
RWL P HPFA+ PFGFG RSC+GRR+AELE++ L++I+ +F+V+
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQ 479
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 118 bits (284), Expect = 3e-26
Identities = 66/174 (37%), Positives = 99/174 (56%), Gaps = 13/174 (7%)
Frame = -2
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS--KNGKRSY-----------LR 458
+++L+AGVDT SNT+S LY ++ + + Q L E+ + G +Y L+
Sbjct: 312 TELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLLK 371
Query: 457 ACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPE 278
A +KE +R+ PVV GN R K+ ++ Y IP+N + H S +P P F P
Sbjct: 372 AVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPA 431
Query: 277 RWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
RWL P HPFA+ PFGFG RSC+GRR+AELE++ L++I+ +F+V+
Sbjct: 432 RWLGEGPTP------HPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQ 479
>X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein.
Length = 521
Score = 105 bits (252), Expect = 2e-22
Identities = 80/262 (30%), Positives = 125/262 (47%), Gaps = 15/262 (5%)
Frame = -2
Query: 856 KRLIECVHQMFVLSNE-LDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKM 680
+R I+ ++QMF S L+L P ++ T ++ + ++ + + + +++
Sbjct: 231 QRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVILSKADIYTQNFYWELRQ 290
Query: 679 NKSKSDDEKPVLEKLL-DINEEYAYIMAS--DMLVAGVDTTSNTMSATLYLMAINQDKQQ 509
S D + +L +LL D + I A+ +ML GVDTTS T+ LY MA N Q
Sbjct: 291 KGSVHHDYRGILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQD 350
Query: 508 KLREEVMSKNGKRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
LR EV++ + L+A IKE +R+ P+ R + + Y IP
Sbjct: 351 MLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIP 410
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L ++ P F P RWL+ + Y F N FG+GVR C+G
Sbjct: 411 AKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITY------FRNLGFGWGVRQCLG 464
Query: 181 RRIAELEVETFLSKIVENFQVE 116
RRIAELE+ FL ++ENF+VE
Sbjct: 465 RRIAELEMTIFLINMLENFRVE 486
>BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family
11, subfamily A, polypeptide 1 protein.
Length = 521
Score = 105 bits (252), Expect = 2e-22
Identities = 80/262 (30%), Positives = 125/262 (47%), Gaps = 15/262 (5%)
Frame = -2
Query: 856 KRLIECVHQMFVLSNE-LDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKM 680
+R I+ ++QMF S L+L P ++ T ++ + ++ + + + +++
Sbjct: 231 QRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQ 290
Query: 679 NKSKSDDEKPVLEKLL-DINEEYAYIMAS--DMLVAGVDTTSNTMSATLYLMAINQDKQQ 509
S D + +L +LL D + I A+ +ML GVDTTS T+ LY MA N Q
Sbjct: 291 KGSVHHDYRGILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQD 350
Query: 508 KLREEVMSKNGKRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
LR EV++ + L+A IKE +R+ P+ R + + Y IP
Sbjct: 351 MLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIP 410
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L ++ P F P RWL+ + Y F N FG+GVR C+G
Sbjct: 411 AKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITY------FRNLGFGWGVRQCLG 464
Query: 181 RRIAELEVETFLSKIVENFQVE 116
RRIAELE+ FL ++ENF+VE
Sbjct: 465 RRIAELEMTIFLINMLENFRVE 486
>M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein.
Length = 521
Score = 104 bits (250), Expect = 4e-22
Identities = 80/262 (30%), Positives = 125/262 (47%), Gaps = 15/262 (5%)
Frame = -2
Query: 856 KRLIECVHQMFVLSNE-LDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKM 680
+R I+ ++QMF S L+L P ++ T ++ + ++ + + + +++
Sbjct: 231 QRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQ 290
Query: 679 NKSKSDDEKPVLEKLL-DINEEYAYIMAS--DMLVAGVDTTSNTMSATLYLMAINQDKQQ 509
S D + +L +LL D + I A+ +ML GVDTTS T+ LY MA N Q
Sbjct: 291 KGSVHHDYRGMLYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQD 350
Query: 508 KLREEVMSKNGKRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
LR EV++ + L+A IKE +R+ P+ R + + Y IP
Sbjct: 351 MLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIP 410
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L ++ P F P RWL+ + Y F N FG+GVR C+G
Sbjct: 411 AKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITY------FRNLGFGWGVRQCLG 464
Query: 181 RRIAELEVETFLSKIVENFQVE 116
RRIAELE+ FL ++ENF+VE
Sbjct: 465 RRIAELEMTIFLINMLENFRVE 486
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 98.7 bits (235), Expect = 2e-20
Identities = 62/189 (32%), Positives = 102/189 (53%), Gaps = 12/189 (6%)
Frame = -2
Query: 628 INEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMS---KNGK----- 473
++++ Y +++ +A V+TT+N++ LY ++ N QQKL +E+ S +N +
Sbjct: 310 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRPREED 369
Query: 472 ---RSYLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVDIAFAHQHLSMMEKYY 305
YL+AC+KE+MR+ P V R T + +LG Y +P+ + Q L E +
Sbjct: 370 LRNMPYLKACLKESMRLTPGVPFTTR-TLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 428
Query: 304 PRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
++F PERWL K +PFA+ PFG G R CIGRR+AEL++ L IV +
Sbjct: 429 EDSSQFRPERWLQEKE------KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 482
Query: 124 QVEWSGSSP 98
++ + + P
Sbjct: 483 DIQATDNEP 491
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 98.3 bits (234), Expect = 3e-20
Identities = 61/189 (32%), Positives = 100/189 (52%), Gaps = 12/189 (6%)
Frame = -2
Query: 628 INEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS------ 467
++++ Y +++ +A V+TT+N++ LY ++ N QQKL +E+ S +
Sbjct: 54 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 113
Query: 466 -----YLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVDIAFAHQHLSMMEKYY 305
YL+AC+KE+MR+ P V R T + +LG Y +P+ + Q L E +
Sbjct: 114 LRNMPYLKACLKESMRLTPSVPFTTR-TLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 172
Query: 304 PRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
++F PERWL K +PFA+ PFG G R CIGRR+AEL++ L IV +
Sbjct: 173 EDSSQFRPERWLQEKE------KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 226
Query: 124 QVEWSGSSP 98
++ + + P
Sbjct: 227 DIQATDNEP 235
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 98.3 bits (234), Expect = 3e-20
Identities = 61/189 (32%), Positives = 100/189 (52%), Gaps = 12/189 (6%)
Frame = -2
Query: 628 INEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS------ 467
++++ Y +++ +A V+TT+N++ LY ++ N QQKL +E+ S +
Sbjct: 169 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 228
Query: 466 -----YLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVDIAFAHQHLSMMEKYY 305
YL+AC+KE+MR+ P V R T + +LG Y +P+ + Q L E +
Sbjct: 229 LRNMPYLKACLKESMRLTPSVPFTTR-TLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 287
Query: 304 PRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
++F PERWL K +PFA+ PFG G R CIGRR+AEL++ L IV +
Sbjct: 288 EDSSQFRPERWLQEKE------KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 341
Query: 124 QVEWSGSSP 98
++ + + P
Sbjct: 342 DIQATDNEP 350
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 98.3 bits (234), Expect = 3e-20
Identities = 61/189 (32%), Positives = 100/189 (52%), Gaps = 12/189 (6%)
Frame = -2
Query: 628 INEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS------ 467
++++ Y +++ +A V+TT+N++ LY ++ N QQKL +E+ S +
Sbjct: 311 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 370
Query: 466 -----YLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVDIAFAHQHLSMMEKYY 305
YL+AC+KE+MR+ P V R T + +LG Y +P+ + Q L E +
Sbjct: 371 LRNMPYLKACLKESMRLTPSVPFTTR-TLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 429
Query: 304 PRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
++F PERWL K +PFA+ PFG G R CIGRR+AEL++ L IV +
Sbjct: 430 EDSSQFRPERWLQEKE------KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 483
Query: 124 QVEWSGSSP 98
++ + + P
Sbjct: 484 DIQATDNEP 492
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 98.3 bits (234), Expect = 3e-20
Identities = 61/189 (32%), Positives = 100/189 (52%), Gaps = 12/189 (6%)
Frame = -2
Query: 628 INEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS------ 467
++++ Y +++ +A V+TT+N++ LY ++ N QQKL +E+ S +
Sbjct: 169 LSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAED 228
Query: 466 -----YLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVDIAFAHQHLSMMEKYY 305
YL+AC+KE+MR+ P V R T + +LG Y +P+ + Q L E +
Sbjct: 229 LRNMPYLKACLKESMRLTPSVPFTTR-TLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 287
Query: 304 PRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
++F PERWL K +PFA+ PFG G R CIGRR+AEL++ L IV +
Sbjct: 288 EDSSQFRPERWLQEKE------KINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 341
Query: 124 QVEWSGSSP 98
++ + + P
Sbjct: 342 DIQATDNEP 350
>M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc
protein.
Length = 239
Score = 95.5 bits (227), Expect = 2e-19
Identities = 70/206 (33%), Positives = 100/206 (48%), Gaps = 14/206 (6%)
Frame = -2
Query: 691 DIKMNKSKSDDEKPVLEKLL-DINEEYAYIMAS--DMLVAGVDTTSNTMSATLYLMAINQ 521
+++ S D + +L +LL D + I A+ +ML GVDTTS T+ LY MA N
Sbjct: 5 ELRQKGSVHHDYRGMLYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNL 64
Query: 520 DKQQKLREEVMSKNGKRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILG 374
Q LR EV++ + L+A IKE +R+ P+ R + +
Sbjct: 65 KVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRD 124
Query: 373 YHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVR 194
Y IP + A L ++ P F P RWL+ + Y F N FG+GVR
Sbjct: 125 YMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITY------FRNLGFGWGVR 178
Query: 193 SCIGRRIAELEVETFLSKIVENFQVE 116
C+GRRIAELE+ FL ++ENF+VE
Sbjct: 179 QCLGRRIAELEMTIFLINMLENFRVE 204
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 90.2 bits (214), Expect = 8e-18
Identities = 65/191 (34%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Frame = -2
Query: 649 VLEKLLDINEEYAYIMASDM-LVAG-VDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG 476
V E LL I A+ M L AG VDTT+ + TL+ +A N D QQ LR+E ++
Sbjct: 290 VAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAA 349
Query: 475 KRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQH 329
S LRA +KE +R+ PV R + + + YHIP +
Sbjct: 350 SISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYS 409
Query: 328 LSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETF 149
L +PRP + P+RWL + G+ F + PFGFG+R C+GRR+AE E+
Sbjct: 410 LGRNAALFPRPERYNPQRWLDIR------GSGRNFHHVPFGFGMRQCLGRRLAEAEMLLL 463
Query: 148 LSKIVENFQVE 116
L ++++F VE
Sbjct: 464 LHHVLKHFLVE 474
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 90.2 bits (214), Expect = 8e-18
Identities = 65/191 (34%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Frame = -2
Query: 649 VLEKLLDINEEYAYIMASDM-LVAG-VDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG 476
V E LL I A+ M L AG VDTT+ + TL+ +A N D QQ LR+E ++
Sbjct: 290 VAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAA 349
Query: 475 KRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQH 329
S LRA +KE +R+ PV R + + + YHIP +
Sbjct: 350 SISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYS 409
Query: 328 LSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETF 149
L +PRP + P+RWL + G+ F + PFGFG+R C+GRR+AE E+
Sbjct: 410 LGRNAALFPRPERYNPQRWLDIR------GSGRNFHHVPFGFGMRQCLGRRLAEAEMLLL 463
Query: 148 LSKIVENFQVE 116
L ++++F VE
Sbjct: 464 LHHVLKHFLVE 474
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 87.8 bits (208), Expect = 4e-17
Identities = 64/191 (33%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Frame = -2
Query: 649 VLEKLLDINEEYAYIMASDM-LVAG-VDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG 476
V E LL+ I A+ M L AG VDTT + TL+ +A N + QQ LR+E ++
Sbjct: 290 VAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAA 349
Query: 475 KRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQH 329
S LRA +KE +R+ PV R + + + YHIP +
Sbjct: 350 SISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVRVFLYS 409
Query: 328 LSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETF 149
L +PRP + P+RWL + G+ F + PFGFG+R C+GRR+AE E+
Sbjct: 410 LGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQCLGRRLAEAEMLLL 463
Query: 148 LSKIVENFQVE 116
L ++++ QVE
Sbjct: 464 LHHVLKHLQVE 474
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 87.8 bits (208), Expect = 4e-17
Identities = 64/191 (33%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Frame = -2
Query: 649 VLEKLLDINEEYAYIMASDM-LVAG-VDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG 476
V E LL+ I A+ M L AG VDTT + TL+ +A N + QQ LR+E ++
Sbjct: 290 VAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAA 349
Query: 475 KRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQH 329
S LRA +KE +R+ PV R + + + YHIP +
Sbjct: 350 SISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYS 409
Query: 328 LSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETF 149
L +PRP + P+RWL + G+ F + PFGFG+R C+GRR+AE E+
Sbjct: 410 LGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQCLGRRLAEAEMLLL 463
Query: 148 LSKIVENFQVE 116
L ++++ QVE
Sbjct: 464 LHHVLKHLQVE 474
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 87.8 bits (208), Expect = 4e-17
Identities = 64/191 (33%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Frame = -2
Query: 649 VLEKLLDINEEYAYIMASDM-LVAG-VDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG 476
V E LL+ I A+ M L AG VDTT + TL+ +A N + QQ LR+E ++
Sbjct: 290 VAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAA 349
Query: 475 KRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQH 329
S LRA +KE +R+ PV R + + + YHIP +
Sbjct: 350 SISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYS 409
Query: 328 LSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETF 149
L +PRP + P+RWL + G+ F + PFGFG+R C+GRR+AE E+
Sbjct: 410 LGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQCLGRRLAEAEMLLL 463
Query: 148 LSKIVENFQVE 116
L ++++ QVE
Sbjct: 464 LHHVLKHLQVE 474
>BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein.
Length = 574
Score = 87.8 bits (208), Expect = 4e-17
Identities = 64/191 (33%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Frame = -2
Query: 649 VLEKLLDINEEYAYIMASDM-LVAG-VDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG 476
V E LL+ I A+ M L AG VDTT + TL+ +A N + QQ LR+E ++
Sbjct: 361 VAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAA 420
Query: 475 KRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQH 329
S LRA +KE +R+ PV R + + + YHIP +
Sbjct: 421 SISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYS 480
Query: 328 LSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETF 149
L +PRP + P+RWL + G+ F + PFGFG+R C+GRR+AE E+
Sbjct: 481 LGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQCLGRRLAEAEMLLL 534
Query: 148 LSKIVENFQVE 116
L ++++ QVE
Sbjct: 535 LHHVLKHLQVE 545
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/191 (33%), Positives = 92/191 (48%), Gaps = 13/191 (6%)
Frame = -2
Query: 649 VLEKLLDINEEYAYIMASDM-LVAG-VDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG 476
V E LL I A+ M L AG VDTT+ + TL+ +A N D QQ LR+E ++
Sbjct: 290 VAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRKESLAAAA 349
Query: 475 KRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQH 329
S LRA +KE +R+ PV R + + + YHIP +
Sbjct: 350 SISEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYS 409
Query: 328 LSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETF 149
L +PRP + P+RWL + G+ + PFGFG+R C+GRR+AE E+
Sbjct: 410 LGRNAALFPRPERYNPQRWLDIR------GSGRNLHHVPFGFGMRQCLGRRLAEAEMLLL 463
Query: 148 LSKIVENFQVE 116
L +++ F VE
Sbjct: 464 LHHVLKRFLVE 474
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 246 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 306 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 359
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 360 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERF 419
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 420 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 246 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 306 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 359
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 360 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERF 419
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 420 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 246 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 306 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 359
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 360 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERF 419
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 420 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 246 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 306 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 359
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 360 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERF 419
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 420 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 246 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 306 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 359
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 360 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERF 419
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 420 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 96 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 155
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 156 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 209
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 210 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERF 269
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 270 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 313
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 173 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 232
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 233 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 286
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 287 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERF 346
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 347 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 390
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 246 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 306 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 359
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 360 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERF 419
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 420 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 246 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 306 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 359
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 360 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERF 419
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 420 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 246 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 306 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 359
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 360 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERF 419
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 420 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 87.0 bits (206), Expect = 8e-17
Identities = 64/229 (27%), Positives = 106/229 (46%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 246 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 306 ------GCETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 359
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 360 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERF 419
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 420 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 86.6 bits (205), Expect = 1e-16
Identities = 63/191 (32%), Positives = 94/191 (49%), Gaps = 13/191 (6%)
Frame = -2
Query: 649 VLEKLLDINEEYAYIMASDM-LVAG-VDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG 476
V E LL+ I A+ M L AG +DTT + TL+ +A N + QQ LR+E ++
Sbjct: 290 VAELLLNAELSPDAIKANSMELTAGSMDTTVFPLLMTLFELARNPNVQQALRQESLAAAA 349
Query: 475 KRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQH 329
S LRA +KE +R+ PV R + + + YHIP +
Sbjct: 350 SISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYS 409
Query: 328 LSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETF 149
L +PRP + P+RWL + G+ F + PFGFG+R C+GRR+AE E+
Sbjct: 410 LGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQCLGRRLAEAEMLLL 463
Query: 148 LSKIVENFQVE 116
L ++++ QVE
Sbjct: 464 LHHVLKHLQVE 474
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 85.0 bits (201), Expect = 3e-16
Identities = 60/198 (30%), Positives = 93/198 (46%), Gaps = 12/198 (6%)
Frame = -2
Query: 673 SKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
S +DDE L DI EE + G DTT+ ++ +LYL+ N + Q+K+ E
Sbjct: 305 SVTDDEGNRLSHE-DIREE-----VDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHE 358
Query: 493 VMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVD 350
+ GK YL IKE +R+ P V R +++ + GY + + +
Sbjct: 359 LDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTE 418
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
L +Y+P P EF PER+ + HP+A PF G R+CIG++ A
Sbjct: 419 AVIIPYALHRDPRYFPNPEEFQPERFFPENAQ-----GRHPYAYVPFSAGPRNCIGQKFA 473
Query: 169 ELEVETFLSKIVENFQVE 116
+E +T LS I+ +F +E
Sbjct: 474 VMEEKTILSCILRHFWIE 491
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 85.0 bits (201), Expect = 3e-16
Identities = 60/198 (30%), Positives = 93/198 (46%), Gaps = 12/198 (6%)
Frame = -2
Query: 673 SKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
S +DDE L DI EE + G DTT+ ++ +LYL+ N + Q+K+ E
Sbjct: 305 SVTDDEGNRLSHE-DIREE-----VDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHE 358
Query: 493 VMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVD 350
+ GK YL IKE +R+ P V R +++ + GY + + +
Sbjct: 359 LDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTE 418
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
L +Y+P P EF PER+ + HP+A PF G R+CIG++ A
Sbjct: 419 AVIIPYALHRDPRYFPNPEEFQPERFFPENAQ-----GRHPYAYVPFSAGPRNCIGQKFA 473
Query: 169 ELEVETFLSKIVENFQVE 116
+E +T LS I+ +F +E
Sbjct: 474 VMEEKTILSCILRHFWIE 491
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 85.0 bits (201), Expect = 3e-16
Identities = 60/198 (30%), Positives = 93/198 (46%), Gaps = 12/198 (6%)
Frame = -2
Query: 673 SKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
S +DDE L DI EE + G DTT+ ++ +LYL+ N + Q+K+ E
Sbjct: 283 SVTDDEGNRLSHE-DIREE-----VDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHE 336
Query: 493 VMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVD 350
+ GK YL IKE +R+ P V R +++ + GY + + +
Sbjct: 337 LDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTE 396
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
L +Y+P P EF PER+ + HP+A PF G R+CIG++ A
Sbjct: 397 AVIIPYALHRDPRYFPNPEEFQPERFFPENAQ-----GRHPYAYVPFSAGPRNCIGQKFA 451
Query: 169 ELEVETFLSKIVENFQVE 116
+E +T LS I+ +F +E
Sbjct: 452 VMEEKTILSCILRHFWIE 469
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 85.0 bits (201), Expect = 3e-16
Identities = 60/198 (30%), Positives = 93/198 (46%), Gaps = 12/198 (6%)
Frame = -2
Query: 673 SKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
S +DDE L DI EE + G DTT+ ++ +LYL+ N + Q+K+ E
Sbjct: 305 SVTDDEGNRLSHE-DIREE-----VDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHE 358
Query: 493 VMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVD 350
+ GK YL IKE +R+ P V R +++ + GY + + +
Sbjct: 359 LDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTE 418
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
L +Y+P P EF PER+ + HP+A PF G R+CIG++ A
Sbjct: 419 AVIIPYALHRDPRYFPNPEEFQPERFFPENAQ-----GRHPYAYVPFSAGPRNCIGQKFA 473
Query: 169 ELEVETFLSKIVENFQVE 116
+E +T LS I+ +F +E
Sbjct: 474 VMEEKTILSCILRHFWIE 491
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 84.6 bits (200), Expect = 4e-16
Identities = 63/229 (27%), Positives = 105/229 (45%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 246 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 306 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 359
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ + L KY+ P +F+PER+
Sbjct: 360 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERF 419
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 420 SKKNKD-----NIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 84.6 bits (200), Expect = 4e-16
Identities = 63/229 (27%), Positives = 105/229 (45%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 245 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 304
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 305 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 358
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ + L KY+ P +F+PER+
Sbjct: 359 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERF 418
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 419 SKKNKD-----NIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 462
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 84.2 bits (199), Expect = 5e-16
Identities = 63/229 (27%), Positives = 105/229 (45%), Gaps = 13/229 (5%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMA 599
T RK++K +E E+ K+ + I SK + L L + + +I A
Sbjct: 246 TNFLRKSVKRMKESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFA 305
Query: 598 SDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRAC 452
G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 306 ------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMV 359
Query: 451 IKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
+ E +R+ P+ R K+ I G IP+ + L KY+ P +F+PER+
Sbjct: 360 VNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERF 419
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 420 SKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 463
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 83.8 bits (198), Expect = 7e-16
Identities = 65/232 (28%), Positives = 108/232 (46%), Gaps = 16/232 (6%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKY---FIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAY 608
T RK +K +E E+ K+ F++ +D K SK + L L + + +
Sbjct: 246 TNFLRKAVKRMKESRLEDTQKHRVDFLQLMIDSHK--NSKETESHKALSDLELVAQSIIF 303
Query: 607 IMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YL 461
I A G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 304 IFA------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYL 357
Query: 460 RACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIP 281
+ E +R+ P+ R K+ I G IP+ + L KY+ P +F+P
Sbjct: 358 DMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLP 417
Query: 280 ERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
ER+ D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 418 ERFSKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 464
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 83.8 bits (198), Expect = 7e-16
Identities = 65/232 (28%), Positives = 108/232 (46%), Gaps = 16/232 (6%)
Frame = -2
Query: 772 TPLFRKTMKMYEEQ--ENLTKY---FIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAY 608
T RK +K +E E+ K+ F++ +D K SK + L L + + +
Sbjct: 246 TNFLRKAVKRMKESRLEDTQKHRVDFLQLMIDSHK--NSKETESHKALSDLELVAQSIIF 303
Query: 607 IMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YL 461
I A G +TTS+ +S +Y +A + D QQKL+EE+ + ++ YL
Sbjct: 304 IFA------GYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYL 357
Query: 460 RACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIP 281
+ E +R+ P+ R K+ I G IP+ + L KY+ P +F+P
Sbjct: 358 DMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLP 417
Query: 280 ERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
ER+ D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 418 ERFSKKNKD-----NIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNF 464
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/166 (31%), Positives = 85/166 (51%), Gaps = 11/166 (6%)
Frame = -2
Query: 589 LVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIKE 443
+ AG +TTS+ +S TLY +A + D QQKL++E+ + ++ YL + E
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNE 362
Query: 442 AMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTN 263
+R+ PV R K+ I G IP+ + L KY+ P EF PER+ +
Sbjct: 363 TLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERF-SK 421
Query: 262 KSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
K D + P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 422 KKDSI-----DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF 462
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/166 (31%), Positives = 85/166 (51%), Gaps = 11/166 (6%)
Frame = -2
Query: 589 LVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIKE 443
+ AG +TTS+ +S TLY +A + D QQKL++E+ + ++ YL + E
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNE 362
Query: 442 AMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTN 263
+R+ PV R K+ I G IP+ + L KY+ P EF PER+ +
Sbjct: 363 TLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERF-SK 421
Query: 262 KSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
K D + P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 422 KKDSI-----DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF 462
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/166 (31%), Positives = 85/166 (51%), Gaps = 11/166 (6%)
Frame = -2
Query: 589 LVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIKE 443
+ AG +TTS+ +S TLY +A + D QQKL++E+ + ++ YL + E
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNE 362
Query: 442 AMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTN 263
+R+ PV R K+ I G IP+ + L KY+ P EF PER+ +
Sbjct: 363 TLRLFPVAIRLERTCMKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERF-SK 421
Query: 262 KSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
K D + P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 422 KKDSI-----DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF 462
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/166 (31%), Positives = 85/166 (51%), Gaps = 11/166 (6%)
Frame = -2
Query: 589 LVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIKE 443
+ AG +TTS+ +S TLY +A + D QQKL++E+ + ++ YL + E
Sbjct: 303 IFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNE 362
Query: 442 AMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTN 263
+R+ PV R K+ I G IP+ + L KY+ P EF PER+ +
Sbjct: 363 TLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERF-SK 421
Query: 262 KSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
K D + P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 422 KKDSI-----DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF 462
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 50/166 (30%), Positives = 84/166 (50%), Gaps = 11/166 (6%)
Frame = -2
Query: 589 LVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIKE 443
+ AG +TTS+ +S +Y +A + D QQK+++E+ + ++ YL + E
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNE 362
Query: 442 AMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTN 263
+R+ PV R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 363 TLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKK 422
Query: 262 KSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 423 NKD-----NIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 50/166 (30%), Positives = 84/166 (50%), Gaps = 11/166 (6%)
Frame = -2
Query: 589 LVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIKE 443
+ AG +TTS+ +S +Y +A + D QQK+++E+ + ++ YL + E
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNE 362
Query: 442 AMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTN 263
+R+ PV R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 363 TLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKK 422
Query: 262 KSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 423 NKD-----NIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 81.8 bits (193), Expect = 3e-15
Identities = 50/166 (30%), Positives = 84/166 (50%), Gaps = 11/166 (6%)
Frame = -2
Query: 589 LVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIKE 443
+ AG +TTS+ +S +Y +A + D QQK+++E+ + ++ YL + E
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNE 362
Query: 442 AMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTN 263
+R+ PV R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 363 TLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKK 422
Query: 262 KSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 423 NKD-----NIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 81.8 bits (193), Expect = 3e-15
Identities = 50/166 (30%), Positives = 84/166 (50%), Gaps = 11/166 (6%)
Frame = -2
Query: 589 LVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIKE 443
+ AG +TTS+ +S +Y +A + D QQK+++E+ + ++ YL + E
Sbjct: 303 IFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNE 362
Query: 442 AMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTN 263
+R+ PV R K+ I G IP+ V + L KY+ P +F+PER+
Sbjct: 363 TLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKK 422
Query: 262 KSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D N P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 423 NKD-----NIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/226 (27%), Positives = 105/226 (46%), Gaps = 12/226 (5%)
Frame = -2
Query: 760 RKTMKMYEEQENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVA 581
+K+++ +Q+N K + LD + K DE +D++ E S L+A
Sbjct: 266 KKSLQAGVKQDNTPKRKYQDFLDIVLSAK----DESGSSFSDIDVHSE-----VSTFLLA 316
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DT + ++S LY +A+N + Q++ REEV + G+ SY CIKE R
Sbjct: 317 GHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCR 376
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
++P V R +K G +P + + + L + P F P R+ S
Sbjct: 377 LIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENS 436
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
D HP+A PF G R+CIG+ A +E++ ++ I+ +F+V
Sbjct: 437 D-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRV 477
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/226 (27%), Positives = 105/226 (46%), Gaps = 12/226 (5%)
Frame = -2
Query: 760 RKTMKMYEEQENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVA 581
+K+++ +Q+N K + LD + K DE +D++ E S L+A
Sbjct: 266 KKSLQAGVKQDNTPKRKYQDFLDIVLSAK----DESGSSFSDIDVHSE-----VSTFLLA 316
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DT + ++S LY +A+N + Q++ REEV + G+ SY CIKE R
Sbjct: 317 GHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCR 376
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
++P V R +K G +P + + + L + P F P R+ S
Sbjct: 377 LIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENS 436
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
D HP+A PF G R+CIG+ A +E++ ++ I+ +F+V
Sbjct: 437 D-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRV 477
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/226 (27%), Positives = 105/226 (46%), Gaps = 12/226 (5%)
Frame = -2
Query: 760 RKTMKMYEEQENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVA 581
+K+++ +Q+N K + LD + K DE +D++ E S L+A
Sbjct: 266 KKSLQAGVKQDNTPKRKYQDFLDIVLSAK----DESGSSFSDIDVHSE-----VSTFLLA 316
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DT + ++S LY +A+N + Q++ REEV + G+ SY CIKE R
Sbjct: 317 GHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCR 376
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
++P V R +K G +P + + + L + P F P R+ S
Sbjct: 377 LIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENS 436
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
D HP+A PF G R+CIG+ A +E++ ++ I+ +F+V
Sbjct: 437 D-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRV 477
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/226 (27%), Positives = 105/226 (46%), Gaps = 12/226 (5%)
Frame = -2
Query: 760 RKTMKMYEEQENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVA 581
+K+++ +Q+N K + LD + K DE +D++ E S L+A
Sbjct: 266 KKSLQAGVKQDNTPKRKYQDFLDIVLSAK----DESGSSFSDIDVHSE-----VSTFLLA 316
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DT + ++S LY +A+N + Q++ REEV + G+ SY CIKE R
Sbjct: 317 GHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCR 376
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
++P V R +K G +P + + + L + P F P R+ S
Sbjct: 377 LIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENS 436
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
D HP+A PF G R+CIG+ A +E++ ++ I+ +F+V
Sbjct: 437 D-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRV 477
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/226 (27%), Positives = 105/226 (46%), Gaps = 12/226 (5%)
Frame = -2
Query: 760 RKTMKMYEEQENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVA 581
+K+++ +Q+N K + LD + K DE +D++ E S L+A
Sbjct: 265 KKSLQAGVKQDNTPKRKYQDFLDIVLSAK----DESGSSFSDIDVHSE-----VSTFLLA 315
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DT + ++S LY +A+N + Q++ REEV + G+ SY CIKE R
Sbjct: 316 GHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCR 375
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
++P V R +K G +P + + + L + P F P R+ S
Sbjct: 376 LIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENS 435
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
D HP+A PF G R+CIG+ A +E++ ++ I+ +F+V
Sbjct: 436 D-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRV 476
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/226 (27%), Positives = 105/226 (46%), Gaps = 12/226 (5%)
Frame = -2
Query: 760 RKTMKMYEEQENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVA 581
+K+++ +Q+N K + LD + K DE +D++ E S L+A
Sbjct: 266 KKSLQAGVKQDNTPKRKYQDFLDIVLSAK----DESGSSFSDIDVHSE-----VSTFLLA 316
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DT + ++S LY +A+N + Q++ REEV + G+ SY CIKE R
Sbjct: 317 GHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCR 376
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
++P V R +K G +P + + + L + P F P R+ S
Sbjct: 377 LIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENS 436
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
D HP+A PF G R+CIG+ A +E++ ++ I+ +F+V
Sbjct: 437 D-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRV 477
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 77.4 bits (182), Expect = 6e-14
Identities = 63/226 (27%), Positives = 105/226 (46%), Gaps = 12/226 (5%)
Frame = -2
Query: 760 RKTMKMYEEQENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVA 581
+K+++ +Q+N K + LD + K DE +D++ E S L+A
Sbjct: 201 KKSLQAGVKQDNTPKRKYQDFLDIVLSAK----DESGSSFSDIDVHSE-----VSTFLLA 251
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DT + ++S LY +A+N + Q++ REEV + G+ SY CIKE R
Sbjct: 252 GHDTLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCR 311
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
++P V R +K G +P + + + L + P F P R+ S
Sbjct: 312 LIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENS 371
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQV 119
D HP+A PF G R+CIG+ A +E++ ++ I+ +F+V
Sbjct: 372 D-----QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRV 412
>M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxylase
protein.
Length = 256
Score = 76.6 bits (180), Expect = 1e-13
Identities = 59/177 (33%), Positives = 85/177 (48%), Gaps = 13/177 (7%)
Frame = -2
Query: 649 VLEKLLDINEEYAYIMASDM-LVAG-VDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG 476
V E LL+ I A+ M L AG VD T + TL+ +A N + QQ LR+E ++
Sbjct: 80 VAELLLNAELSPDAIKANCMELTAGSVDRTVFPLLMTLFELARNPNVQQPLRQESLAPAA 139
Query: 475 KRS-----------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQH 329
S LRA +KE +R+ PV R + + + YHIP +
Sbjct: 140 SISEHPQKATTELPLLRAALKETLRLYPVGLILERVVSSDLVLQNYHIPAGTLVRVFLYS 199
Query: 328 LSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEV 158
L +PRP + P+RWL K G+ F + PFGFG+R C+GRR+AE ++
Sbjct: 200 LGRNPALFPRPERYNPQRWLDIK------GSGRNFYHVPFGFGMRQCLGRRLAEADM 250
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 76.2 bits (179), Expect = 1e-13
Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 11/167 (6%)
Frame = -2
Query: 592 MLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIK 446
++ A DTTS T+ +Y +A + D QQKL+EE+ + ++ YL +
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLANKAPVTYDALVQMEYLDMVVN 361
Query: 445 EAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLT 266
E +R+ PVVS R K+ I G IP+ + + L KY+ P +F PER+
Sbjct: 362 ETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSK 421
Query: 265 NKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D + + PFG G R+CIG R A ++ + + ++NF
Sbjct: 422 KNKDSI-----DLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNF 463
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 75.4 bits (177), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 279 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 338
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 339 DHARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 398
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 399 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 449
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 450 FTLLSSGDA 458
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 75.4 bits (177), Expect = 3e-13
Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 11/167 (6%)
Frame = -2
Query: 592 MLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIK 446
++ A DTTS T+ +Y +A + D QQKL+EE+ + ++ YL +
Sbjct: 192 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVN 251
Query: 445 EAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLT 266
E +R+ PVVS R K+ I G IP+ + + L KY+ P +F PER+
Sbjct: 252 ETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSK 311
Query: 265 NKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D + + PFG G R+CIG R A ++ + + ++NF
Sbjct: 312 KNKDSI-----DLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNF 353
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 75.4 bits (177), Expect = 3e-13
Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 11/167 (6%)
Frame = -2
Query: 592 MLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIK 446
++ A DTTS T+ +Y +A + D QQKL+EE+ + ++ YL +
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVN 361
Query: 445 EAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLT 266
E +R+ PVVS R K+ I G IP+ + + L KY+ P +F PER+
Sbjct: 362 ETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSK 421
Query: 265 NKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D + + PFG G R+CIG R A ++ + + ++NF
Sbjct: 422 KNKDSI-----DLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNF 463
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 75.4 bits (177), Expect = 3e-13
Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 11/167 (6%)
Frame = -2
Query: 592 MLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIK 446
++ A DTTS T+ +Y +A + D QQKL+EE+ + ++ YL +
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVN 361
Query: 445 EAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLT 266
E +R+ PVVS R K+ I G IP+ + + L KY+ P +F PER+
Sbjct: 362 ETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSK 421
Query: 265 NKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D + + PFG G R+CIG R A ++ + + ++NF
Sbjct: 422 KNKDSI-----DLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNF 463
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 75.4 bits (177), Expect = 3e-13
Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 11/167 (6%)
Frame = -2
Query: 592 MLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIK 446
++ A DTTS T+ +Y +A + D QQKL+EE+ + ++ YL +
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVN 361
Query: 445 EAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLT 266
E +R+ PVVS R K+ I G IP+ + + L KY+ P +F PER+
Sbjct: 362 ETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSK 421
Query: 265 NKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D + + PFG G R+CIG R A ++ + + ++NF
Sbjct: 422 KNKDSI-----DLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNF 463
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 75.4 bits (177), Expect = 3e-13
Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 11/167 (6%)
Frame = -2
Query: 592 MLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIK 446
++ A DTTS T+ +Y +A + D QQKL+EE+ + ++ YL +
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVN 361
Query: 445 EAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLT 266
E +R+ PVVS R K+ I G IP+ + + L KY+ P +F PER+
Sbjct: 362 ETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSK 421
Query: 265 NKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D + + PFG G R+CIG R A ++ + + ++NF
Sbjct: 422 KNKDSI-----DLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNF 463
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 75.4 bits (177), Expect = 3e-13
Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 11/167 (6%)
Frame = -2
Query: 592 MLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIK 446
++ A DTTS T+ +Y +A + D QQKL+EE+ + ++ YL +
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVN 361
Query: 445 EAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLT 266
E +R+ PVVS R K+ I G IP+ + + L KY+ P +F PER+
Sbjct: 362 ETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSK 421
Query: 265 NKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
D + + PFG G R+CIG R A ++ + + ++NF
Sbjct: 422 KNKDSI-----DLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNF 463
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 279 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 338
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 339 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 398
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 399 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 449
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 450 FTLLPSGDA 458
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 279 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 338
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 339 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 398
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 399 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 449
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 450 FTLLPSGDA 458
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 464
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 248 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 307
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 308 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 367
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 368 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 418
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 419 FTLLPSGDA 427
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 279 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 338
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 339 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 398
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 399 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 449
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 450 FTLLPSGDA 458
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGTHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 249 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 308
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 309 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 368
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 369 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 419
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 420 FTLLPSGDA 428
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 279 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 338
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 339 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 398
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 399 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 449
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 450 FTLLPSGDA 458
>AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 249 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 308
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 309 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 368
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 369 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 419
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 420 FTLLPSGDA 428
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 279 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 338
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 339 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 398
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 399 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 449
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 450 FTLLPSGDA 458
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 279 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 338
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 339 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 398
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 399 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 449
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 450 FTLLPSGDA 458
>AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 249 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 308
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 309 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 368
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 369 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 419
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 420 FTLLPSGDA 428
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 279 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 338
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 339 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 398
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 399 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 449
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 450 FTLLPSGDA 458
>AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens
cDNA FLJ30054 fis, clone ADRGL1000160, highly similar to
CYTOCHROME P450 XXIB (EC 1.14.99.10). ).
Length = 465
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/191 (30%), Positives = 97/191 (50%), Gaps = 15/191 (7%)
Frame = -2
Query: 628 INEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG--------- 476
+ E + ++ A D+L+ G +TT+NT+S + + + QQ+L+EE+ + G
Sbjct: 247 LQEGHVHMAAVDLLIGGTETTANTLSWAAVFLLHHPEIQQRLQEELDHELGPGASSSRVP 306
Query: 475 -----KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMME 314
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 307 YKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDE 366
Query: 313 KYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIV 134
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L++++
Sbjct: 367 TVWERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLL 417
Query: 133 ENFQVEWSGSS 101
+ F + SG +
Sbjct: 418 QAFTLLPSGDA 428
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 74.9 bits (176), Expect = 3e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPENFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 403
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 187 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 246
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 247 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 306
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 307 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 357
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 358 FTLLPSGDA 366
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 74.9 bits (176), Expect = 3e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 279 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 338
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 339 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 398
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 399 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 449
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 450 FTLLPSGDA 458
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 74.5 bits (175), Expect = 4e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 279 EGHLHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 338
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 339 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 398
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 399 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 449
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 450 FTLLPSGDA 458
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 243 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 299
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 300 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 359
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 360 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 414
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 415 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 460
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 74.5 bits (175), Expect = 4e-13
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLFHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHQPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPKTFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAEDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 74.5 bits (175), Expect = 4e-13
Identities = 63/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 74.1 bits (174), Expect = 6e-13
Identities = 49/179 (27%), Positives = 87/179 (48%), Gaps = 12/179 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
+EEY + + D+ +AG DTT+N++ L M++N D Q+K+ EE+ ++
Sbjct: 338 DEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDK 397
Query: 478 GKRSYLRACIKEAMRILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYP 302
+ Y A I E R+ VV + T E +L GY IP+ I + +
Sbjct: 398 AQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWE 457
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
+P +F P R+L ++ + F PFG G R C+G ++A++E+ ++++F
Sbjct: 458 KPEDFYPNRFLDDQGQLI---KKETFI--PFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 74.1 bits (174), Expect = 6e-13
Identities = 49/179 (27%), Positives = 87/179 (48%), Gaps = 12/179 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
+EEY + + D+ +AG DTT+N++ L M++N D Q+K+ EE+ ++
Sbjct: 338 DEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDK 397
Query: 478 GKRSYLRACIKEAMRILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYP 302
+ Y A I E R+ VV + T E +L GY IP+ I + +
Sbjct: 398 AQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWE 457
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
+P +F P R+L ++ + F PFG G R C+G ++A++E+ ++++F
Sbjct: 458 KPEDFYPNRFLDDQGQLI---KKETFI--PFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511
>M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein.
Length = 230
Score = 73.3 bits (172), Expect = 1e-12
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 14 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHLEIQQRLQEELDHELGPGASSSRVPYK 73
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 74 DRARLPLLIATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 133
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 134 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 184
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 185 FTLLPSGDA 193
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 73.3 bits (172), Expect = 1e-12
Identities = 62/226 (27%), Positives = 94/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S Y++A N D Q+K
Sbjct: 311 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYVLATNPDCQEK 367
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 368 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 427
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 428 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 482
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
R+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 483 VRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 528
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/216 (24%), Positives = 101/216 (46%), Gaps = 12/216 (5%)
Frame = -2
Query: 724 LTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSAT 545
L ++F+ LD+ M++ K+D ++E ++++AG +TT+N +
Sbjct: 272 LPQHFVDAYLDE--MDQGKNDPSST-------FSKENLIFSVGELIIAGTETTTNVLRWA 322
Query: 544 LYLMAINQDKQQKLREEV---MSKNGKRS--------YLRACIKEAMRILPVVS-GNMRR 401
+ MA+ + Q ++++E+ M NGK S Y A + E +R +V G
Sbjct: 323 ILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHA 382
Query: 400 TTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFA 221
T+++ + GY IP+ + + EKY+ P F PER+L + Y+
Sbjct: 383 TSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSG---YFAKKEALV 439
Query: 220 NSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEW 113
PF G R C+G +A +E+ F + +++ F + +
Sbjct: 440 --PFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHF 473
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/216 (24%), Positives = 101/216 (46%), Gaps = 12/216 (5%)
Frame = -2
Query: 724 LTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSAT 545
L ++F+ LD+ M++ K+D ++E ++++AG +TT+N +
Sbjct: 272 LPQHFVDAYLDE--MDQGKNDPSST-------FSKENLIFSVGELIIAGTETTTNVLRWA 322
Query: 544 LYLMAINQDKQQKLREEV---MSKNGKRS--------YLRACIKEAMRILPVVS-GNMRR 401
+ MA+ + Q ++++E+ M NGK S Y A + E +R +V G
Sbjct: 323 ILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHA 382
Query: 400 TTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFA 221
T+++ + GY IP+ + + EKY+ P F PER+L + Y+
Sbjct: 383 TSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSG---YFAKKEALV 439
Query: 220 NSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEW 113
PF G R C+G +A +E+ F + +++ F + +
Sbjct: 440 --PFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHF 473
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 72.9 bits (171), Expect = 1e-12
Identities = 53/216 (24%), Positives = 101/216 (46%), Gaps = 12/216 (5%)
Frame = -2
Query: 724 LTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSAT 545
L ++F+ LD+ M++ K+D ++E ++++AG +TT+N +
Sbjct: 272 LPQHFVDAYLDE--MDQGKNDPSST-------FSKENLIFSVGELIIAGTETTTNVLRWA 322
Query: 544 LYLMAINQDKQQKLREEV---MSKNGKRS--------YLRACIKEAMRILPVVS-GNMRR 401
+ MA+ + Q ++++E+ M NGK S Y A + E +R +V G
Sbjct: 323 ILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHA 382
Query: 400 TTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFA 221
T+++ + GY IP+ + + EKY+ P F PER+L + Y+
Sbjct: 383 TSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSG---YFAKKEALV 439
Query: 220 NSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEW 113
PF G R C+G +A +E+ F + +++ F + +
Sbjct: 440 --PFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHF 473
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 72.9 bits (171), Expect = 1e-12
Identities = 58/189 (30%), Positives = 96/189 (50%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G + T+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTENTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 72.5 bits (170), Expect = 2e-12
Identities = 62/226 (27%), Positives = 93/226 (41%), Gaps = 12/226 (5%)
Frame = -2
Query: 685 KMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQK 506
K N S+ P + + L ++E A L+AG + +NT+S YL+A N D Q+K
Sbjct: 310 KPNPSRQHQPSP-MARPLTVDEIVG--QAFIFLIAGYEIITNTLSFATYLLATNPDCQEK 366
Query: 505 LREEVMSKNGKRS------------YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIP 362
L EV K YL I E +R+ P R ++ +LG IP
Sbjct: 367 LLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIP 426
Query: 361 ENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIG 182
+ A L +++P P F PER+ PF PFG G RSC+G
Sbjct: 427 AGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQ-----QHRPFTYLPFGAGPRSCLG 481
Query: 181 RRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIF 44
+ LEV+ L ++ F+ + + Q GP N ++
Sbjct: 482 VHLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVY 527
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 72.5 bits (170), Expect = 2e-12
Identities = 49/167 (29%), Positives = 80/167 (47%), Gaps = 11/167 (6%)
Frame = -2
Query: 592 MLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIK 446
++ A DTTS T+ +Y +A + D QQKL+EE+ + ++ YL +
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVN 361
Query: 445 EAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLT 266
E +R+ PVVS R K+ I G IP+ + + L KY+ P +F PE +
Sbjct: 362 ETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFS 421
Query: 265 NKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
K+ + + PFG G R+CIG R A ++ + + ++NF
Sbjct: 422 KKNK----DSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNF 464
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 72.5 bits (170), Expect = 2e-12
Identities = 49/167 (29%), Positives = 80/167 (47%), Gaps = 11/167 (6%)
Frame = -2
Query: 592 MLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS-----------YLRACIK 446
++ A DTTS T+ +Y +A + D QQKL+EE+ + ++ YL +
Sbjct: 302 IIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVN 361
Query: 445 EAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLT 266
E +R+ PVVS R K+ I G IP+ + + L KY+ P +F PE +
Sbjct: 362 ETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFS 421
Query: 265 NKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
K+ + + PFG G R+CIG R A ++ + + ++NF
Sbjct: 422 KKNK----DSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNF 464
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 72.1 bits (169), Expect = 2e-12
Identities = 58/189 (30%), Positives = 96/189 (50%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNMRR-TTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + TT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHCTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G R C+G +A LE+ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGARVCLGEPLARLELFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 70.9 bits (166), Expect = 5e-12
Identities = 57/189 (30%), Positives = 96/189 (50%), Gaps = 15/189 (7%)
Frame = -2
Query: 622 EEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG----------- 476
E + ++ A D+L+ G +TT+NT+S + + + + QQ+L+EE+ + G
Sbjct: 278 EGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYK 337
Query: 475 ---KRSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ L A I E +R+ PVV + RTT+ +I GY IPE I Q + E
Sbjct: 338 DRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETV 397
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+ RP EF P+R+L +P N+ A FG G C+G +A L++ L+++++
Sbjct: 398 WERPHEFWPDRFL----EP--GKNSRALA---FGCGAPVCLGEPLARLDLFVVLTRLLQA 448
Query: 127 FQVEWSGSS 101
F + SG +
Sbjct: 449 FTLLPSGDA 457
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 70.5 bits (165), Expect = 7e-12
Identities = 49/198 (24%), Positives = 90/198 (45%), Gaps = 12/198 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPRVEQTSINYF 68
+ PR + + F
Sbjct: 466 FSVAAGQPRPSHSRVVSF 483
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 68.5 bits (160), Expect = 3e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 68.5 bits (160), Expect = 3e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 294 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 353
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 354 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 413
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 414 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 468
Query: 121 VEWSGSSPR 95
PR
Sbjct: 469 FSVPTGQPR 477
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 167 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 226
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 227 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 286
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 287 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 341
Query: 121 VEWSGSSPR 95
PR
Sbjct: 342 FSVPTGQPR 350
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 294 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 353
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 354 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 413
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 414 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 468
Query: 121 VEWSGSSPR 95
PR
Sbjct: 469 FSVPTGQPR 477
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDMIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 290 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 349
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 350 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 409
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 410 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 464
Query: 121 VEWSGSSPR 95
PR
Sbjct: 465 FSVPTGQPR 473
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 240 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 299
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 300 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 359
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 360 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 414
Query: 121 VEWSGSSPR 95
PR
Sbjct: 415 FSVPTGQPR 423
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDEVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 240 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 299
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 300 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 359
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 360 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 414
Query: 121 VEWSGSSPR 95
PR
Sbjct: 415 FSVPTGQPR 423
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 240 NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 299
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 300 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 359
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 360 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 414
Query: 121 VEWSGSSPR 95
PR
Sbjct: 415 FSVPTGQPR 423
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 291 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 350
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 351 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 410
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 411 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 465
Query: 121 VEWSGSSPR 95
PR
Sbjct: 466 FSVPTGQPR 474
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 12/189 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKN 479
N+E I+ +D+ AG+ TTS T++ L LM ++ D Q+++++E+ M
Sbjct: 360 NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQ 419
Query: 478 GKRSYLRACIKEAMRILPVVS-GNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R +V G T+++ + G+ IP+ + + E +
Sbjct: 420 AHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWE 479
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+P F PE +L + P A PF G R+C+G +A +E+ F + ++++F
Sbjct: 480 KPFRFHPEHFLDAQGH-----FVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFS 534
Query: 121 VEWSGSSPR 95
PR
Sbjct: 535 FSVPTGQPR 543
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 67.7 bits (158), Expect = 5e-11
Identities = 45/166 (27%), Positives = 82/166 (49%), Gaps = 11/166 (6%)
Frame = -2
Query: 586 VAGVDTTSNTMSATLYLMAINQDKQQKLREEVM----SKN-------GKRSYLRACIKEA 440
+AG +T++N ++ T+ ++ + +L+ EV SK G+ YL +KE+
Sbjct: 301 IAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKES 360
Query: 439 MRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNK 260
+R+ P G R +E I G +P N + F+ + M+ Y+ P F P+R+
Sbjct: 361 LRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGA 420
Query: 259 SDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
P F PF G RSCIG++ A++EV+ ++K+++ +
Sbjct: 421 PKPR-------FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLE 459
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 67.7 bits (158), Expect = 5e-11
Identities = 45/166 (27%), Positives = 82/166 (49%), Gaps = 11/166 (6%)
Frame = -2
Query: 586 VAGVDTTSNTMSATLYLMAINQDKQQKLREEVM----SKN-------GKRSYLRACIKEA 440
+AG +T++N ++ T+ ++ + +L+ EV SK G+ YL +KE+
Sbjct: 301 IAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKES 360
Query: 439 MRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNK 260
+R+ P G R +E I G +P N + F+ + M+ Y+ P F P+R+
Sbjct: 361 LRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNPDRFGPGA 420
Query: 259 SDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
P F PF G RSCIG++ A++EV+ ++K+++ +
Sbjct: 421 PKPR-------FTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLE 459
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.7 bits (153), Expect = 2e-10
Identities = 59/258 (22%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Frame = -2
Query: 850 LIECVHQMFVLSNELDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKS 671
L++ V + + N+ K + L K ++ Y+E+ I LD + K
Sbjct: 214 LVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDS--ITNMLDTLMQAKM 271
Query: 670 KSDDEKPVLEKLLDI-NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
SD+ ++ ++ ++ + D+ AGV+TT++ + TL + N ++KL EE
Sbjct: 272 NSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEE 331
Query: 493 V-----------MSKNGKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVD 350
+ +S + L A I+E +R+ PV + + +G + + + +
Sbjct: 332 IDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTE 391
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
+ L EK + +P +F+PER+L L + + PFG G RSCIG +A
Sbjct: 392 VIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSV---SYLPFGAGPRSCIGEILA 448
Query: 169 ELEVETFLSKIVENFQVE 116
E+ ++ +++ F +E
Sbjct: 449 RQELFLIMAWLLQRFDLE 466
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.7 bits (153), Expect = 2e-10
Identities = 59/258 (22%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Frame = -2
Query: 850 LIECVHQMFVLSNELDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKS 671
L++ V + + N+ K + L K ++ Y+E+ I LD + K
Sbjct: 214 LVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDS--ITNMLDTLMQAKM 271
Query: 670 KSDDEKPVLEKLLDI-NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
SD+ ++ ++ ++ + D+ AGV+TT++ + TL + N ++KL EE
Sbjct: 272 NSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEE 331
Query: 493 V-----------MSKNGKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVD 350
+ +S + L A I+E +R+ PV + + +G + + + +
Sbjct: 332 IDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTE 391
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
+ L EK + +P +F+PER+L L + + PFG G RSCIG +A
Sbjct: 392 VIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSV---SYLPFGAGPRSCIGEILA 448
Query: 169 ELEVETFLSKIVENFQVE 116
E+ ++ +++ F +E
Sbjct: 449 RQELFLIMAWLLQRFDLE 466
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.7 bits (153), Expect = 2e-10
Identities = 59/258 (22%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Frame = -2
Query: 850 LIECVHQMFVLSNELDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKS 671
L++ V + + N+ K + L K ++ Y+E+ I LD + K
Sbjct: 214 LVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDS--ITNMLDTLMQAKM 271
Query: 670 KSDDEKPVLEKLLDI-NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
SD+ ++ ++ ++ + D+ AGV+TT++ + TL + N ++KL EE
Sbjct: 272 NSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEE 331
Query: 493 V-----------MSKNGKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVD 350
+ +S + L A I+E +R+ PV + + +G + + + +
Sbjct: 332 IDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTE 391
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
+ L EK + +P +F+PER+L L + + PFG G RSCIG +A
Sbjct: 392 VIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSV---SYLPFGAGPRSCIGEILA 448
Query: 169 ELEVETFLSKIVENFQVE 116
E+ ++ +++ F +E
Sbjct: 449 RQELFLIMAWLLQRFDLE 466
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 65.7 bits (153), Expect = 2e-10
Identities = 59/258 (22%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Frame = -2
Query: 850 LIECVHQMFVLSNELDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKS 671
L++ V + + N+ K + L K ++ Y+E+ I LD + K
Sbjct: 214 LVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDS--ITNMLDTLMQAKM 271
Query: 670 KSDDEKPVLEKLLDI-NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
SD+ ++ ++ ++ + D+ AGV+TT++ + TL + N ++KL EE
Sbjct: 272 NSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEE 331
Query: 493 V-----------MSKNGKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVD 350
+ +S + L A I+E +R+ PV + + +G + + + +
Sbjct: 332 IDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTE 391
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
+ L EK + +P +F+PER+L L + + PFG G RSCIG +A
Sbjct: 392 VIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSV---SYLPFGAGPRSCIGEILA 448
Query: 169 ELEVETFLSKIVENFQVE 116
E+ ++ +++ F +E
Sbjct: 449 RQELFLIMAWLLQRFDLE 466
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.7 bits (153), Expect = 2e-10
Identities = 59/258 (22%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Frame = -2
Query: 850 LIECVHQMFVLSNELDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKS 671
L++ V + + N+ K + L K ++ Y+E+ I LD + K
Sbjct: 214 LVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDS--ITNMLDTLMQAKM 271
Query: 670 KSDDEKPVLEKLLDI-NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
SD+ ++ ++ ++ + D+ AGV+TT++ + TL + N ++KL EE
Sbjct: 272 NSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEE 331
Query: 493 V-----------MSKNGKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVD 350
+ +S + L A I+E +R+ PV + + +G + + + +
Sbjct: 332 IDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTE 391
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
+ L EK + +P +F+PER+L L + + PFG G RSCIG +A
Sbjct: 392 VIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSV---SYLPFGAGPRSCIGEILA 448
Query: 169 ELEVETFLSKIVENFQVE 116
E+ ++ +++ F +E
Sbjct: 449 RQELFLIMAWLLQRFDLE 466
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.7 bits (153), Expect = 2e-10
Identities = 59/258 (22%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Frame = -2
Query: 850 LIECVHQMFVLSNELDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKS 671
L++ V + + N+ K + L K ++ Y+E+ I LD + K
Sbjct: 214 LVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDS--ITNMLDTLMQAKM 271
Query: 670 KSDDEKPVLEKLLDI-NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
SD+ ++ ++ ++ + D+ AGV+TT++ + TL + N ++KL EE
Sbjct: 272 NSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEE 331
Query: 493 V-----------MSKNGKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVD 350
+ +S + L A I+E +R+ PV + + +G + + + +
Sbjct: 332 IDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTE 391
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
+ L EK + +P +F+PER+L L + + PFG G RSCIG +A
Sbjct: 392 VIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSV---SYLPFGAGPRSCIGEILA 448
Query: 169 ELEVETFLSKIVENFQVE 116
E+ ++ +++ F +E
Sbjct: 449 RQELFLIMAWLLQRFDLE 466
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.7 bits (153), Expect = 2e-10
Identities = 59/258 (22%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Frame = -2
Query: 850 LIECVHQMFVLSNELDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKS 671
L++ V + + N+ K + L K ++ Y+E+ I LD + K
Sbjct: 214 LVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDS--ITNMLDTLMQAKM 271
Query: 670 KSDDEKPVLEKLLDI-NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
SD+ ++ ++ ++ + D+ AGV+TT++ + TL + N ++KL EE
Sbjct: 272 NSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEE 331
Query: 493 V-----------MSKNGKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVD 350
+ +S + L A I+E +R+ PV + + +G + + + +
Sbjct: 332 IDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTE 391
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
+ L EK + +P +F+PER+L L + + PFG G RSCIG +A
Sbjct: 392 VIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSV---SYLPFGAGPRSCIGEILA 448
Query: 169 ELEVETFLSKIVENFQVE 116
E+ ++ +++ F +E
Sbjct: 449 RQELFLIMAWLLQRFDLE 466
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.7 bits (153), Expect = 2e-10
Identities = 59/258 (22%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Frame = -2
Query: 850 LIECVHQMFVLSNELDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKS 671
L++ V + + N+ K + L K ++ Y+E+ I LD + K
Sbjct: 214 LVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDS--ITNMLDTLMQAKM 271
Query: 670 KSDDEKPVLEKLLDI-NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
SD+ ++ ++ ++ + D+ AGV+TT++ + TL + N ++KL EE
Sbjct: 272 NSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEE 331
Query: 493 V-----------MSKNGKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVD 350
+ +S + L A I+E +R+ PV + + +G + + + +
Sbjct: 332 IDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTE 391
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
+ L EK + +P +F+PER+L L + + PFG G RSCIG +A
Sbjct: 392 VIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSV---SYLPFGAGPRSCIGEILA 448
Query: 169 ELEVETFLSKIVENFQVE 116
E+ ++ +++ F +E
Sbjct: 449 RQELFLIMAWLLQRFDLE 466
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 65.7 bits (153), Expect = 2e-10
Identities = 59/258 (22%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Frame = -2
Query: 850 LIECVHQMFVLSNELDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKS 671
L++ V + + N+ K + L K ++ Y+E+ I LD + K
Sbjct: 214 LVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDS--ITNMLDTLMQAKM 271
Query: 670 KSDDEKPVLEKLLDI-NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE 494
SD+ ++ ++ ++ + D+ AGV+TT++ + TL + N ++KL EE
Sbjct: 272 NSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEE 331
Query: 493 V-----------MSKNGKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILG-YHIPENVD 350
+ +S + L A I+E +R+ PV + + +G + + + +
Sbjct: 332 IDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTE 391
Query: 349 IAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIA 170
+ L EK + +P +F+PER+L L + + PFG G RSCIG +A
Sbjct: 392 VIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSV---SYLPFGAGPRSCIGEILA 448
Query: 169 ELEVETFLSKIVENFQVE 116
E+ ++ +++ F +E
Sbjct: 449 RQELFLIMAWLLQRFDLE 466
>AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family
26, subfamily C, polypeptide 1 protein.
Length = 522
Score = 65.3 bits (152), Expect = 3e-10
Identities = 37/128 (28%), Positives = 63/128 (49%), Gaps = 1/128 (0%)
Frame = -2
Query: 478 GKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPR 299
G+ Y+ +KE +R+LP VSG R + + + GY IP+ + ++ + Y
Sbjct: 364 GRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRS 423
Query: 298 PTE-FIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
P E F PER+ + D G + F PFG G RSC+G+ +A+ ++ ++V
Sbjct: 424 PPEGFDPERFGAAREDS--RGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRT-- 479
Query: 121 VEWSGSSP 98
W ++P
Sbjct: 480 ARWELATP 487
>Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for
aromatase P-450. ).
Length = 503
Score = 64.9 bits (151), Expect = 4e-10
Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 15/244 (6%)
Frame = -2
Query: 802 LKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSD-----DEKPVLEK 638
+KP I+ +S L++K K ++ ++ + I + I + + E + EK
Sbjct: 229 IKPDIFFKISW-LYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEK 287
Query: 637 LLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSY-- 464
D+ E +ML+A DT S ++ L+L+A + + ++ + +E+ + G+R
Sbjct: 288 RGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKI 347
Query: 463 --------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ I E+MR PVV MR+ ++ I GY + + +I + +E +
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-F 406
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+P+P EF E + N P Y PFGFG R C G+ IA + ++ L ++
Sbjct: 407 FPKPNEFTLENFAKNV--PYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRR 457
Query: 127 FQVE 116
F V+
Sbjct: 458 FHVK 461
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 316 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 375
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 376 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 435
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 436 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 475
>X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for
aromatase (estrogen synthetase). ).
Length = 503
Score = 64.9 bits (151), Expect = 4e-10
Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 15/244 (6%)
Frame = -2
Query: 802 LKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSD-----DEKPVLEK 638
+KP I+ +S L++K K ++ ++ + I + I + + E + EK
Sbjct: 229 IKPDIFFKISW-LYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEK 287
Query: 637 LLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSY-- 464
D+ E +ML+A DT S ++ L+L+A + + ++ + +E+ + G+R
Sbjct: 288 RGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKI 347
Query: 463 --------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ I E+MR PVV MR+ ++ I GY + + +I + +E +
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-F 406
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+P+P EF E + N P Y PFGFG R C G+ IA + ++ L ++
Sbjct: 407 FPKPNEFTLENFAKNV--PYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRR 457
Query: 127 FQVE 116
F V+
Sbjct: 458 FHVK 461
>M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase
cytochrome P-450 gene, exon 10. ).
Length = 503
Score = 64.9 bits (151), Expect = 4e-10
Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 15/244 (6%)
Frame = -2
Query: 802 LKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSD-----DEKPVLEK 638
+KP I+ +S L++K K ++ ++ + I + I + + E + EK
Sbjct: 229 IKPDIFFKISW-LYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEK 287
Query: 637 LLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSY-- 464
D+ E +ML+A DT S ++ L+L+A + + ++ + +E+ + G+R
Sbjct: 288 RGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKI 347
Query: 463 --------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ I E+MR PVV MR+ ++ I GY + + +I + +E +
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-F 406
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+P+P EF E + N P Y PFGFG R C G+ IA + ++ L ++
Sbjct: 407 FPKPNEFTLENFAKNV--PYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRR 457
Query: 127 FQVE 116
F V+
Sbjct: 458 FHVK 461
>M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase
mRNA, complete cds. ).
Length = 503
Score = 64.9 bits (151), Expect = 4e-10
Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 15/244 (6%)
Frame = -2
Query: 802 LKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSD-----DEKPVLEK 638
+KP I+ +S L++K K ++ ++ + I + I + + E + EK
Sbjct: 229 IKPDIFFKISW-LYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEK 287
Query: 637 LLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSY-- 464
D+ E +ML+A DT S ++ L+L+A + + ++ + +E+ + G+R
Sbjct: 288 RGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKI 347
Query: 463 --------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ I E+MR PVV MR+ ++ I GY + + +I + +E +
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-F 406
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+P+P EF E + N P Y PFGFG R C G+ IA + ++ L ++
Sbjct: 407 FPKPNEFTLENFAKNV--PYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRR 457
Query: 127 FQVE 116
F V+
Sbjct: 458 FHVK 461
>M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase
(Aro1) mRNA, complete cds. ).
Length = 419
Score = 64.9 bits (151), Expect = 4e-10
Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 15/244 (6%)
Frame = -2
Query: 802 LKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSD-----DEKPVLEK 638
+KP I+ +S L++K K ++ ++ + I + I + + E + EK
Sbjct: 145 IKPDIFFKISW-LYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEK 203
Query: 637 LLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSY-- 464
D+ E +ML+A DT S ++ L+L+A + + ++ + +E+ + G+R
Sbjct: 204 RGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKI 263
Query: 463 --------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ I E+MR PVV MR+ ++ I GY + + +I + +E +
Sbjct: 264 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-F 322
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+P+P EF E + N P Y PFGFG R C G+ IA + ++ L ++
Sbjct: 323 FPKPNEFTLENFAKNV--PYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRR 373
Query: 127 FQVE 116
F V+
Sbjct: 374 FHVK 377
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 316 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 375
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 376 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 435
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 436 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 475
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 316 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 375
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 376 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 435
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 436 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 475
>DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfamily
19 subfamily A polypeptide 1 protein.
Length = 503
Score = 64.9 bits (151), Expect = 4e-10
Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 15/244 (6%)
Frame = -2
Query: 802 LKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSD-----DEKPVLEK 638
+KP I+ +S L++K K ++ ++ + I + I + + E + EK
Sbjct: 229 IKPDIFFKISW-LYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEK 287
Query: 637 LLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSY-- 464
D+ E +ML+A DT S ++ L+L+A + + ++ + +E+ + G+R
Sbjct: 288 RGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKI 347
Query: 463 --------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ I E+MR PVV MR+ ++ I GY + + +I + +E +
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-F 406
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+P+P EF E + N P Y PFGFG R C G+ IA + ++ L ++
Sbjct: 407 FPKPNEFTLENFAKNV--PYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRR 457
Query: 127 FQVE 116
F V+
Sbjct: 458 FHVK 461
>BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 64.9 bits (151), Expect = 4e-10
Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 15/244 (6%)
Frame = -2
Query: 802 LKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSD-----DEKPVLEK 638
+KP I+ +S L++K K ++ ++ + I + I + + E + EK
Sbjct: 229 IKPDIFFKISW-LYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEK 287
Query: 637 LLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSY-- 464
D+ E +ML+A DT S ++ L+L+A + + ++ + +E+ + G+R
Sbjct: 288 RGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKI 347
Query: 463 --------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ I E+MR PVV MR+ ++ I GY + + +I + +E +
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-F 406
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+P+P EF E + N P Y PFGFG R C G+ IA + ++ L ++
Sbjct: 407 FPKPNEFTLENFAKNV--PYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRR 457
Query: 127 FQVE 116
F V+
Sbjct: 458 FHVK 461
>BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 64.9 bits (151), Expect = 4e-10
Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 15/244 (6%)
Frame = -2
Query: 802 LKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSD-----DEKPVLEK 638
+KP I+ +S L++K K ++ ++ + I + I + + E + EK
Sbjct: 229 IKPDIFFKISW-LYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEK 287
Query: 637 LLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSY-- 464
D+ E +ML+A DT S ++ L+L+A + + ++ + +E+ + G+R
Sbjct: 288 RGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKI 347
Query: 463 --------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ I E+MR PVV MR+ ++ I GY + + +I + +E +
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-F 406
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+P+P EF E + N P Y PFGFG R C G+ IA + ++ L ++
Sbjct: 407 FPKPNEFTLENFAKNV--PYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRR 457
Query: 127 FQVE 116
F V+
Sbjct: 458 FHVK 461
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 317 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 376
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 377 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 436
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 437 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 476
>AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 64.9 bits (151), Expect = 4e-10
Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 15/244 (6%)
Frame = -2
Query: 802 LKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSD-----DEKPVLEK 638
+KP I+ +S L++K K ++ ++ + I + I + + E + EK
Sbjct: 229 IKPDIFFKISW-LYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATELILAEK 287
Query: 637 LLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSY-- 464
D+ E +ML+A DT S ++ L+L+A + + ++ + +E+ + G+R
Sbjct: 288 RGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKI 347
Query: 463 --------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ I E+MR PVV MR+ ++ I GY + + +I + +E +
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-F 406
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+P+P EF E + N P Y PFGFG R C G+ IA + ++ L ++
Sbjct: 407 FPKPNEFTLENFAKNV--PYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRR 457
Query: 127 FQVE 116
F V+
Sbjct: 458 FHVK 461
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 302 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 361
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 362 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 421
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 422 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 461
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 317 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 376
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 377 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 436
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 437 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 476
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 316 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 375
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 376 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 435
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 436 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 475
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 317 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 376
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 377 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 436
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 437 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 476
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 316 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 375
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 376 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 435
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 436 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 475
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 302 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 361
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 362 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 421
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 422 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 461
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 317 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 376
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 377 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 436
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 437 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 476
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 316 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 375
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 376 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 435
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 436 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 475
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 64.9 bits (151), Expect = 4e-10
Identities = 50/165 (30%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 302 GHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 361
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 362 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 421
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 422 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 461
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 64.5 bits (150), Expect = 5e-10
Identities = 59/216 (27%), Positives = 105/216 (48%), Gaps = 13/216 (6%)
Frame = -2
Query: 718 KYFIKKALDDIKMNKSKSDDEKPVLEKL-LDINEEYAYIMASDMLVAGVDTTSNTMSATL 542
K F K + DI + + EK + E + +++E + D+ AG DT + +S +L
Sbjct: 271 KTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSL 330
Query: 541 YLMAINQDKQQKLREEVMSKNGK--------RS---YLRACIKEAMRILPVVSGNM-RRT 398
+ +N Q+K++EE+ + G+ RS Y+ A I E R +V + T
Sbjct: 331 MYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSLVPFTIPHST 390
Query: 397 TKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFAN 218
T++ ++ G++IP+ + ++ +K + P+EF+PER+LT
Sbjct: 391 TRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDG---AIDKVLSEKV 447
Query: 217 SPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
FG G R CIG +A EV FL+ +++ +VE+S
Sbjct: 448 IIFGMGKRKCIGETVARWEVFLFLAILLQ--RVEFS 481
>M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatase
protein.
Length = 419
Score = 64.5 bits (150), Expect = 5e-10
Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 15/244 (6%)
Frame = -2
Query: 802 LKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSD-----DEKPVLEK 638
+KP I+ +S L++K K ++ ++ + I + I + + E + EK
Sbjct: 145 IKPDIFFKISW-LYKKYEKSVKDLKDAIEVLIAEKRCRISTEEKLEECMDFATELILAEK 203
Query: 637 LLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSY-- 464
D+ E +ML+A DT S ++ L+L+A + + ++ + +E+ + G+R
Sbjct: 204 RGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKI 263
Query: 463 --------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ I E+MR PVV MR+ ++ I GY + + +I + +E +
Sbjct: 264 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-F 322
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+P+P EF E + N P Y PFGFG R C G+ IA + ++ L ++
Sbjct: 323 FPKPNEFTLENFAKNV--PYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRR 373
Query: 127 FQVE 116
F V+
Sbjct: 374 FHVK 377
>J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein.
Length = 503
Score = 64.5 bits (150), Expect = 5e-10
Identities = 61/244 (25%), Positives = 112/244 (45%), Gaps = 15/244 (6%)
Frame = -2
Query: 802 LKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSD-----DEKPVLEK 638
+KP I+ +S L++K K ++ ++ + I + I + + E + EK
Sbjct: 229 IKPDIFFKISW-LYKKYEKSVKDLKDAIEVLIAEKRCRISTEEKLEECMDFATELILAEK 287
Query: 637 LLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSY-- 464
D+ E +ML+A DT S ++ L+L+A + + ++ + +E+ + G+R
Sbjct: 288 RGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKI 347
Query: 463 --------LRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKY 308
+ I E+MR PVV MR+ ++ I GY + + +I + +E +
Sbjct: 348 DDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHRLE-F 406
Query: 307 YPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVEN 128
+P+P EF E + N P Y PFGFG R C G+ IA + ++ L ++
Sbjct: 407 FPKPNEFTLENFAKNV--PYRYFQ-------PFGFGPRGCAGKYIAMVMMKAILVTLLRR 457
Query: 127 FQVE 116
F V+
Sbjct: 458 FHVK 461
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 64.5 bits (150), Expect = 5e-10
Identities = 50/165 (30%), Positives = 74/165 (44%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT+ +S LY MA+ + Q + REEV GK +YL CIKE+ R
Sbjct: 316 GHDTTTGGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 375
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 376 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 435
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 436 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 475
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 64.1 bits (149), Expect = 6e-10
Identities = 60/216 (27%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Frame = -2
Query: 718 KYFIKKALDDIKMNKSKSDDEKPVLEKL-LDINEEYAYIMASDMLVAGVDTTSNTMSATL 542
K F K + DI + + EK + E + +++E + D+ AG DT + +S +L
Sbjct: 271 KTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSL 330
Query: 541 YLMAINQDKQQKLREEVMSKNGK--------RS---YLRACIKEAMRILPVVSGNM-RRT 398
+ +N Q+K++EE+ + G+ RS Y+ A I E R V + T
Sbjct: 331 MYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHST 390
Query: 397 TKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFAN 218
T++ ++ G++IP+ + ++ +K + P+EF+PER+LT
Sbjct: 391 TRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDG---AIDKVLSEKV 447
Query: 217 SPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
FG G R CIG IA EV FL+ +++ +VE+S
Sbjct: 448 IIFGMGKRKCIGETIARWEVFLFLAILLQ--RVEFS 481
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 64.1 bits (149), Expect = 6e-10
Identities = 57/225 (25%), Positives = 100/225 (44%), Gaps = 14/225 (6%)
Frame = -2
Query: 748 KMYEEQENLTKYFIKKALDD--IKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGV 575
K+ E QE++ + +D IKM K K + + + E I A+D+L AG
Sbjct: 247 KVKEHQESMDINNPRDFIDCFLIKMEKEKQNQQS-------EFTIENLVITAADLLGAGT 299
Query: 574 DTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKNGKRSYLRACIKEAMRIL 428
+TTS T+ L L+ + + K++EE+ M G Y A + E R +
Sbjct: 300 ETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRGHMPYTDAVVHEVQRYI 359
Query: 427 PVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDP 251
++ ++ T + Y IP+ I + + K +P P F P +L +
Sbjct: 360 DLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGN- 418
Query: 250 LYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
+ ++ F PF G R C+G +A +E+ FL+ I++NF ++
Sbjct: 419 --FKKSNYFM--PFSAGKRICVGEGLARMELFLFLTFILQNFNLK 459
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 64.1 bits (149), Expect = 6e-10
Identities = 57/225 (25%), Positives = 100/225 (44%), Gaps = 14/225 (6%)
Frame = -2
Query: 748 KMYEEQENLTKYFIKKALDD--IKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGV 575
K+ E QE++ + +D IKM K K + + + E I A+D+L AG
Sbjct: 225 KVKEHQESMDINNPRDFIDCFLIKMEKEKQNQQS-------EFTIENLVITAADLLGAGT 277
Query: 574 DTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKNGKRSYLRACIKEAMRIL 428
+TTS T+ L L+ + + K++EE+ M G Y A + E R +
Sbjct: 278 ETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYI 337
Query: 427 PVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDP 251
++ ++ T + Y IP+ I + + K +P P F P +L +
Sbjct: 338 DLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGN- 396
Query: 250 LYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
+ ++ F PF G R C+G +A +E+ FL+ I++NF ++
Sbjct: 397 --FKKSNYFM--PFSAGKRICVGEGLARMELFLFLTFILQNFNLK 437
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 64.1 bits (149), Expect = 6e-10
Identities = 60/216 (27%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Frame = -2
Query: 718 KYFIKKALDDIKMNKSKSDDEKPVLEKL-LDINEEYAYIMASDMLVAGVDTTSNTMSATL 542
K F K + DI + + EK + E + +++E + D+ AG DT + +S +L
Sbjct: 271 KTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSL 330
Query: 541 YLMAINQDKQQKLREEVMSKNGK--------RS---YLRACIKEAMRILPVVSGNM-RRT 398
+ +N Q+K++EE+ + G+ RS Y+ A I E R V + T
Sbjct: 331 MYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHST 390
Query: 397 TKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFAN 218
T++ ++ G++IP+ + ++ +K + P+EF+PER+LT
Sbjct: 391 TRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDG---AIDKVLSEKV 447
Query: 217 SPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
FG G R CIG IA EV FL+ +++ +VE+S
Sbjct: 448 IIFGMGKRKCIGETIARWEVFLFLAILLQ--RVEFS 481
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 64.1 bits (149), Expect = 6e-10
Identities = 60/216 (27%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Frame = -2
Query: 718 KYFIKKALDDIKMNKSKSDDEKPVLEKL-LDINEEYAYIMASDMLVAGVDTTSNTMSATL 542
K F K + DI + + EK + E + +++E + D+ AG DT + +S +L
Sbjct: 271 KTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSL 330
Query: 541 YLMAINQDKQQKLREEVMSKNGK--------RS---YLRACIKEAMRILPVVSGNM-RRT 398
+ +N Q+K++EE+ + G+ RS Y+ A I E R V + T
Sbjct: 331 MYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHST 390
Query: 397 TKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFAN 218
T++ ++ G++IP+ + ++ +K + P+EF+PER+LT
Sbjct: 391 TRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDG---AIDKVLSEKV 447
Query: 217 SPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
FG G R CIG IA EV FL+ +++ +VE+S
Sbjct: 448 IIFGMGKRKCIGETIARWEVFLFLAILLQ--RVEFS 481
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 64.1 bits (149), Expect = 6e-10
Identities = 57/225 (25%), Positives = 100/225 (44%), Gaps = 14/225 (6%)
Frame = -2
Query: 748 KMYEEQENLTKYFIKKALDD--IKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGV 575
K+ E QE++ + +D IKM K K + + + E I A+D+L AG
Sbjct: 247 KVKEHQESMDINNPRDFIDCFLIKMEKEKQNQQS-------EFTIENLVITAADLLGAGT 299
Query: 574 DTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKNGKRSYLRACIKEAMRIL 428
+TTS T+ L L+ + + K++EE+ M G Y A + E R +
Sbjct: 300 ETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYI 359
Query: 427 PVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDP 251
++ ++ T + Y IP+ I + + K +P P F P +L +
Sbjct: 360 DLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGN- 418
Query: 250 LYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
+ ++ F PF G R C+G +A +E+ FL+ I++NF ++
Sbjct: 419 --FKKSNYFM--PFSAGKRICVGEGLARMELFLFLTFILQNFNLK 459
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 64.1 bits (149), Expect = 6e-10
Identities = 60/216 (27%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Frame = -2
Query: 718 KYFIKKALDDIKMNKSKSDDEKPVLEKL-LDINEEYAYIMASDMLVAGVDTTSNTMSATL 542
K F K + DI + + EK + E + +++E + D+ AG DT + +S +L
Sbjct: 243 KTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSL 302
Query: 541 YLMAINQDKQQKLREEVMSKNGK--------RS---YLRACIKEAMRILPVVSGNM-RRT 398
+ +N Q+K++EE+ + G+ RS Y+ A I E R V + T
Sbjct: 303 MYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHST 362
Query: 397 TKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFAN 218
T++ ++ G++IP+ + ++ +K + P+EF+PER+LT
Sbjct: 363 TRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDG---AIDKVLSEKV 419
Query: 217 SPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
FG G R CIG IA EV FL+ +++ +VE+S
Sbjct: 420 IIFGMGKRKCIGETIARWEVFLFLAILLQ--RVEFS 453
>AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1
protein.
Length = 251
Score = 64.1 bits (149), Expect = 6e-10
Identities = 60/216 (27%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Frame = -2
Query: 718 KYFIKKALDDIKMNKSKSDDEKPVLEKL-LDINEEYAYIMASDMLVAGVDTTSNTMSATL 542
K F K + DI + + EK + E + +++E + D+ AG DT + +S +L
Sbjct: 10 KTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSL 69
Query: 541 YLMAINQDKQQKLREEVMSKNGK--------RS---YLRACIKEAMRILPVVSGNM-RRT 398
+ +N Q+K++EE+ + G+ RS Y+ A I E R V + T
Sbjct: 70 MYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHST 129
Query: 397 TKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFAN 218
T++ ++ G++IP+ + ++ +K + P+EF+PER+LT
Sbjct: 130 TRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDG---AIDKVLSEKV 186
Query: 217 SPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
FG G R CIG IA EV FL+ +++ +VE+S
Sbjct: 187 IIFGMGKRKCIGETIARWEVFLFLAILLQ--RVEFS 220
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 64.1 bits (149), Expect = 6e-10
Identities = 57/225 (25%), Positives = 100/225 (44%), Gaps = 14/225 (6%)
Frame = -2
Query: 748 KMYEEQENLTKYFIKKALDD--IKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGV 575
K+ E QE++ + +D IKM K K + + + E I A+D+L AG
Sbjct: 247 KVKEHQESMDINNPRDFIDCFLIKMEKEKQNQQS-------EFTIENLVITAADLLGAGT 299
Query: 574 DTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKNGKRSYLRACIKEAMRIL 428
+TTS T+ L L+ + + K++EE+ M G Y A + E R +
Sbjct: 300 ETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYI 359
Query: 427 PVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDP 251
++ ++ T + Y IP+ I + + K +P P F P +L +
Sbjct: 360 DLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGN- 418
Query: 250 LYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
+ ++ F PF G R C+G +A +E+ FL+ I++NF ++
Sbjct: 419 --FKKSNYFM--PFSAGKRICVGEGLARMELFLFLTFILQNFNLK 459
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 64.1 bits (149), Expect = 6e-10
Identities = 43/193 (22%), Positives = 91/193 (47%), Gaps = 16/193 (8%)
Frame = -2
Query: 601 ASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKN----------------GKR 470
++++L G +TT++ ++ + + + QK+REE+ SK +
Sbjct: 225 STELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQL 284
Query: 469 SYLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTE 290
Y+ IKE +R+ P V G R K + + GY IP+ ++ ++ + + + E
Sbjct: 285 KYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEE 344
Query: 289 FIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
F P+R++ + +A F+ PFG G+RSC+G+ A++ ++ F ++ + +
Sbjct: 345 FNPDRFMLPHPE-----DASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLL 399
Query: 109 GSSPRVEQTSINY 71
P ++ + Y
Sbjct: 400 NGPPTMKTSPTVY 412
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 64.1 bits (149), Expect = 6e-10
Identities = 43/193 (22%), Positives = 91/193 (47%), Gaps = 16/193 (8%)
Frame = -2
Query: 601 ASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKN----------------GKR 470
++++L G +TT++ ++ + + + QK+REE+ SK +
Sbjct: 294 STELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQL 353
Query: 469 SYLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTE 290
Y+ IKE +R+ P V G R K + + GY IP+ ++ ++ + + + E
Sbjct: 354 KYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEE 413
Query: 289 FIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
F P+R++ + +A F+ PFG G+RSC+G+ A++ ++ F ++ + +
Sbjct: 414 FNPDRFMLPHPE-----DASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLL 468
Query: 109 GSSPRVEQTSINY 71
P ++ + Y
Sbjct: 469 NGPPTMKTSPTVY 481
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 64.1 bits (149), Expect = 6e-10
Identities = 57/225 (25%), Positives = 100/225 (44%), Gaps = 14/225 (6%)
Frame = -2
Query: 748 KMYEEQENLTKYFIKKALDD--IKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGV 575
K+ E QE++ + +D IKM K K + + + E I A+D+L AG
Sbjct: 247 KVKEHQESMDINNPRDFIDCFLIKMEKEKQNQQS-------EFTIENLVITAADLLGAGT 299
Query: 574 DTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKNGKRSYLRACIKEAMRIL 428
+TTS T+ L L+ + + K++EE+ M G Y A + E R +
Sbjct: 300 ETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYI 359
Query: 427 PVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDP 251
++ ++ T + Y IP+ I + + K +P P F P +L +
Sbjct: 360 DLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGN- 418
Query: 250 LYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
+ ++ F PF G R C+G +A +E+ FL+ I++NF ++
Sbjct: 419 --FKKSNYFM--PFSAGKRICVGEGLARMELFLFLTFILQNFNLK 459
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 64.1 bits (149), Expect = 6e-10
Identities = 60/216 (27%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Frame = -2
Query: 718 KYFIKKALDDIKMNKSKSDDEKPVLEKL-LDINEEYAYIMASDMLVAGVDTTSNTMSATL 542
K F K + DI + + EK + E + +++E + D+ AG DT + +S +L
Sbjct: 271 KTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSL 330
Query: 541 YLMAINQDKQQKLREEVMSKNGK--------RS---YLRACIKEAMRILPVVSGNM-RRT 398
+ +N Q+K++EE+ + G+ RS Y+ A I E R V + T
Sbjct: 331 MYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHST 390
Query: 397 TKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFAN 218
T++ ++ G++IP+ + ++ +K + P+EF+PER+LT
Sbjct: 391 TRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDG---AIDKVLSEKV 447
Query: 217 SPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
FG G R CIG IA EV FL+ +++ +VE+S
Sbjct: 448 IIFGMGKRKCIGETIARWEVFLFLAILLQ--RVEFS 481
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 64.1 bits (149), Expect = 6e-10
Identities = 37/114 (32%), Positives = 57/114 (50%)
Frame = -2
Query: 466 YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEF 287
YL + E +R+ PV R K+ I G IP+ + L KY+ P EF
Sbjct: 26 YLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEF 85
Query: 286 IPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
PER+ + K D + P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 86 RPERF-SKKKDSI-----DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF 133
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 64.1 bits (149), Expect = 6e-10
Identities = 37/114 (32%), Positives = 57/114 (50%)
Frame = -2
Query: 466 YLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEF 287
YL + E +R+ PV R K+ I G IP+ + L KY+ P EF
Sbjct: 13 YLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEF 72
Query: 286 IPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
PER+ + K D + P+ +PFG G R+CIG R A + ++ L ++++NF
Sbjct: 73 RPERF-SKKKDSI-----DPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNF 120
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 64.1 bits (149), Expect = 6e-10
Identities = 60/216 (27%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Frame = -2
Query: 718 KYFIKKALDDIKMNKSKSDDEKPVLEKL-LDINEEYAYIMASDMLVAGVDTTSNTMSATL 542
K F K + DI + + EK + E + +++E + D+ AG DT + +S +L
Sbjct: 271 KTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSL 330
Query: 541 YLMAINQDKQQKLREEVMSKNGK--------RS---YLRACIKEAMRILPVVSGNM-RRT 398
+ +N Q+K++EE+ + G+ RS Y+ A I E R V + T
Sbjct: 331 MYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHST 390
Query: 397 TKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFAN 218
T++ ++ G++IP+ + ++ +K + P+EF+PER+LT
Sbjct: 391 TRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDG---AIDKVLSEKV 447
Query: 217 SPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
FG G R CIG IA EV FL+ +++ +VE+S
Sbjct: 448 IIFGMGKRKCIGETIARWEVFLFLAILLQ--RVEFS 481
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 64.1 bits (149), Expect = 6e-10
Identities = 43/193 (22%), Positives = 91/193 (47%), Gaps = 16/193 (8%)
Frame = -2
Query: 601 ASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKN----------------GKR 470
++++L G +TT++ ++ + + + QK+REE+ SK +
Sbjct: 294 STELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQL 353
Query: 469 SYLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTE 290
Y+ IKE +R+ P V G R K + + GY IP+ ++ ++ + + + E
Sbjct: 354 KYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEE 413
Query: 289 FIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
F P+R++ + +A F+ PFG G+RSC+G+ A++ ++ F ++ + +
Sbjct: 414 FNPDRFMLPHPE-----DASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLL 468
Query: 109 GSSPRVEQTSINY 71
P ++ + Y
Sbjct: 469 NGPPTMKTSPTVY 481
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 63.7 bits (148), Expect = 8e-10
Identities = 59/216 (27%), Positives = 104/216 (48%), Gaps = 13/216 (6%)
Frame = -2
Query: 718 KYFIKKALDDIKMNKSKSDDEKPVLEKL-LDINEEYAYIMASDMLVAGVDTTSNTMSATL 542
K F K + DI + + EK + E + +++E + D+ AG DT + +S +L
Sbjct: 271 KTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTAISWSL 330
Query: 541 YLMAINQDKQQKLREEVMSKNGK--------RS---YLRACIKEAMRILPVVSGNM-RRT 398
+ +N Q+K++EE+ + G+ RS Y+ A I E R V + T
Sbjct: 331 MYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHST 390
Query: 397 TKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFAN 218
T++ ++ G++IP+ + ++ +K + P+EF+PER+LT
Sbjct: 391 TRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDG---AIDKVLSEKV 447
Query: 217 SPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
FG G R CIG +A EV FL+ +++ +VE+S
Sbjct: 448 IIFGMGKRKCIGETVARWEVFLFLAILLQ--RVEFS 481
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 63.3 bits (147), Expect = 1e-09
Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 12/165 (7%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMS-----------KNGKRSYLRACIKEAMR 434
G DTT++ +S LY +A+ + Q + REEV GK +YL CIKE+ R
Sbjct: 316 GHDTTTSGISWFLYCIALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFR 375
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V R+ +K + G +P I+ L +P P F R+ T +
Sbjct: 376 LYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENA 435
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
HPFA PF G R+CIG++ A E++ + + F+
Sbjct: 436 S-----KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFE 475
>AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein.
Length = 522
Score = 62.9 bits (146), Expect = 1e-09
Identities = 36/128 (28%), Positives = 62/128 (48%), Gaps = 1/128 (0%)
Frame = -2
Query: 478 GKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPR 299
G+ Y+ +KE +R+LP VSG R + + + GY IP+ + ++ + Y
Sbjct: 364 GRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRS 423
Query: 298 PTE-FIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
P E F PER+ + D G + PFG G RSC+G+ +A+ ++ ++V
Sbjct: 424 PPEGFDPERFGAAREDS--RGASSRLHYIPFGGGARSCLGQELAQAVLQLLAVELVRT-- 479
Query: 121 VEWSGSSP 98
W ++P
Sbjct: 480 ARWELATP 487
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 62.9 bits (146), Expect = 1e-09
Identities = 60/216 (27%), Positives = 102/216 (47%), Gaps = 13/216 (6%)
Frame = -2
Query: 718 KYFIKKALDDIKMNKSKSDDEKPVLEKL-LDINEEYAYIMASDMLVAGVDTTSNTMSATL 542
K F K + DI + + EK + E + +++E + D+ AG DT + S +L
Sbjct: 271 KTFEKGHIRDITDSLIEHCQEKQLDENANVQLSDEKIINIVLDLFGAGFDTVTTATSWSL 330
Query: 541 YLMAINQDKQQKLREEVMSKNGK--------RS---YLRACIKEAMRILPVVSGNM-RRT 398
+ +N Q+K++EE+ + G+ RS Y+ A I E R V + T
Sbjct: 331 MYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHSSFVPFTIPHST 390
Query: 397 TKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFAN 218
T++ ++ G++IP+ + + +K + P+EF+PER+LT
Sbjct: 391 TRDTSLKGFYIPKGRCVFVNQWQIDHDQKLWVNPSEFLPERFLTPDG---AIDKVLSEKV 447
Query: 217 SPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWS 110
FG G R CIG IA EV FL+ +++ +VE+S
Sbjct: 448 IIFGMGKRKCIGETIARWEVFLFLAILLQ--RVEFS 481
>X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C
protein.
Length = 356
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/180 (26%), Positives = 82/180 (45%), Gaps = 12/180 (6%)
Frame = -2
Query: 619 EYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKNGK 473
E I A+D+L AG +TTS T+ L L+ + + K++EE+ M G
Sbjct: 151 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGH 210
Query: 472 RSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRP 296
Y A + E R + ++ ++ T + Y IP+ I + + K +P P
Sbjct: 211 MPYTDAVVHEVQRYIDLIPTSLPHAVTCDIKFRNYLIPKGTTILTSLTSVLHDNKEFPNP 270
Query: 295 TEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
F P +L + + ++ F PF G R C+G +A +E+ FL+ I++NF ++
Sbjct: 271 EMFDPRHFLDEGGN---FKKSNYFM--PFSAGKRICVGEGLARMELFLFLTFILQNFNLK 325
>L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 217
Score = 62.5 bits (145), Expect = 2e-09
Identities = 47/180 (26%), Positives = 82/180 (45%), Gaps = 12/180 (6%)
Frame = -2
Query: 619 EYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKNGK 473
E I A+D+L AG +TTS T+ L L+ + + K++EE+ M G
Sbjct: 12 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRGH 71
Query: 472 RSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRP 296
Y A + E R + ++ ++ T + Y IP+ I + + K +P P
Sbjct: 72 MPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNP 131
Query: 295 TEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
F P +L + + ++ F PF G R C+G +A +E+ FL+ I++NF ++
Sbjct: 132 EMFDPRHFLDEGGN---FKKSNYFM--PFSAGKRICVGEGLARMELFLFLTFILQNFNLK 186
>M12079-1|AAA52152.1| 191|Homo sapiens POR protein.
Length = 191
Score = 61.3 bits (142), Expect = 4e-09
Identities = 51/187 (27%), Positives = 92/187 (49%), Gaps = 12/187 (6%)
Frame = -2
Query: 634 LDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGK------ 473
+ +++E + D+ AG DT + +S +L + +N Q+K++EE+ + G+
Sbjct: 6 VQLSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRL 65
Query: 472 --RS---YLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEK 311
RS Y+ A I E R V + TT++ ++ G++IP+ + ++ +K
Sbjct: 66 SDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQK 125
Query: 310 YYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVE 131
+ P+EF+PER+LT FG G R CIG +A EV FL+ +++
Sbjct: 126 LWVNPSEFLPERFLTPDG---AIDKVLSEKVIIFGMGKRKCIGETVARWEVFLFLAILLQ 182
Query: 130 NFQVEWS 110
+VE+S
Sbjct: 183 --RVEFS 187
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 60.9 bits (141), Expect = 6e-09
Identities = 49/160 (30%), Positives = 74/160 (46%), Gaps = 14/160 (8%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG-----------KRSYLRACIKEAMR 434
G DTT++ +S LY +A + Q++ REE+ S G + Y CIKEA+R
Sbjct: 322 GHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALR 381
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V G R + G +P+ + + + L K +P P F P R+ +
Sbjct: 382 LYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSA 441
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIA--ELEVETFLS 143
H A PF G R+CIG++ A EL+V T L+
Sbjct: 442 Q-------HSHAFLPFSGGSRNCIGKQFAMNELKVATALT 474
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 60.9 bits (141), Expect = 6e-09
Identities = 49/160 (30%), Positives = 74/160 (46%), Gaps = 14/160 (8%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG-----------KRSYLRACIKEAMR 434
G DTT++ +S LY +A + Q++ REE+ S G + Y CIKEA+R
Sbjct: 322 GHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALR 381
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V G R + G +P+ + + + L K +P P F P R+ +
Sbjct: 382 LYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSA 441
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIA--ELEVETFLS 143
H A PF G R+CIG++ A EL+V T L+
Sbjct: 442 Q-------HSHAFLPFSGGSRNCIGKQFAMNELKVATALT 474
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 60.9 bits (141), Expect = 6e-09
Identities = 51/194 (26%), Positives = 81/194 (41%), Gaps = 12/194 (6%)
Frame = -2
Query: 643 EKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS- 467
E D +E + AG DTTS+ +S LY +A + QQ+ R+E+ G S
Sbjct: 294 ENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS 353
Query: 466 ----------YLRACIKEAMRILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSM 320
Y CIKE +R+ V R K G +P + + L
Sbjct: 354 ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHH 413
Query: 319 MEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSK 140
++ P F P R+ S+ + HP+A PF G+R+CIG+ A +E + ++
Sbjct: 414 NPYFWEDPQVFNPLRFSRENSEKI-----HPYAFIPFSAGLRNCIGQHFAIIECKVAVAL 468
Query: 139 IVENFQVEWSGSSP 98
+ F++ S P
Sbjct: 469 TLLRFKLAPDHSRP 482
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 60.9 bits (141), Expect = 6e-09
Identities = 51/194 (26%), Positives = 81/194 (41%), Gaps = 12/194 (6%)
Frame = -2
Query: 643 EKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS- 467
E D +E + AG DTTS+ +S LY +A + QQ+ R+E+ G S
Sbjct: 294 ENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS 353
Query: 466 ----------YLRACIKEAMRILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSM 320
Y CIKE +R+ V R K G +P + + L
Sbjct: 354 ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHH 413
Query: 319 MEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSK 140
++ P F P R+ S+ + HP+A PF G+R+CIG+ A +E + ++
Sbjct: 414 NPYFWEDPQVFNPLRFSRENSEKI-----HPYAFIPFSAGLRNCIGQHFAIIECKVAVAL 468
Query: 139 IVENFQVEWSGSSP 98
+ F++ S P
Sbjct: 469 TLLRFKLAPDHSRP 482
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 60.9 bits (141), Expect = 6e-09
Identities = 51/194 (26%), Positives = 81/194 (41%), Gaps = 12/194 (6%)
Frame = -2
Query: 643 EKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS- 467
E D +E + AG DTTS+ +S LY +A + QQ+ R+E+ G S
Sbjct: 294 ENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS 353
Query: 466 ----------YLRACIKEAMRILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSM 320
Y CIKE +R+ V R K G +P + + L
Sbjct: 354 ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHH 413
Query: 319 MEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSK 140
++ P F P R+ S+ + HP+A PF G+R+CIG+ A +E + ++
Sbjct: 414 NPYFWEDPQVFNPLRFSRENSEKI-----HPYAFIPFSAGLRNCIGQHFAIIECKVAVAL 468
Query: 139 IVENFQVEWSGSSP 98
+ F++ S P
Sbjct: 469 TLLRFKLAPDHSRP 482
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 60.9 bits (141), Expect = 6e-09
Identities = 51/194 (26%), Positives = 81/194 (41%), Gaps = 12/194 (6%)
Frame = -2
Query: 643 EKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRS- 467
E D +E + AG DTTS+ +S LY +A + QQ+ R+E+ G S
Sbjct: 294 ENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS 353
Query: 466 ----------YLRACIKEAMRILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSM 320
Y CIKE +R+ V R K G +P + + L
Sbjct: 354 ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHH 413
Query: 319 MEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSK 140
++ P F P R+ S+ + HP+A PF G+R+CIG+ A +E + ++
Sbjct: 414 NPYFWEDPQVFNPLRFSRENSEKI-----HPYAFIPFSAGLRNCIGQHFAIIECKVAVAL 468
Query: 139 IVENFQVEWSGSSP 98
+ F++ S P
Sbjct: 469 TLLRFKLAPDHSRP 482
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 60.1 bits (139), Expect = 1e-08
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 12/176 (6%)
Frame = -2
Query: 607 IMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEV-----------MSKNGKRSYL 461
+ +D+ AG +TTS T+ L ++ + ++KL EE+ + + Y+
Sbjct: 291 VTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYM 350
Query: 460 RACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFI 284
A ++E R + +V N+ T++ GY IP+ + + + +P P +F
Sbjct: 351 DAVVREIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFK 410
Query: 283 PERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVE 116
PE +L N++ Y + PF G R C G +A +E+ L I+++F ++
Sbjct: 411 PEHFL-NENGKFKYSDYF----KPFSTGKRVCAGEGLARMELFLLLCAILQHFNLK 461
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 60.1 bits (139), Expect = 1e-08
Identities = 49/160 (30%), Positives = 74/160 (46%), Gaps = 14/160 (8%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG-----------KRSYLRACIKEAMR 434
G DTT++ +S LY +A + Q++ REE+ S G + Y CIKEA+R
Sbjct: 322 GHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALR 381
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V G R + G +P+ + + + L K +P P F P R+ +
Sbjct: 382 LFPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSA 441
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIA--ELEVETFLS 143
H A PF G R+CIG++ A EL+V T L+
Sbjct: 442 Q-------HSHAFLPFSGGSRNCIGKQFAMNELKVATALT 474
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 12/179 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGK--------- 473
+EE D+ AG +TTS T+ L MA+ + Q+K++ E+ G+
Sbjct: 297 HEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAAR 356
Query: 472 --RSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R+ ++ N+ R T + + GYH+P+ I L +
Sbjct: 357 ESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWA 416
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
P F P+ +L N + F PF G R+C+G ++A E+ F + +++ F
Sbjct: 417 TPDTFNPDHFLENGQ----FKKREAF--MPFSIGKRACLGEQLARTELFIFFTSLMQKF 469
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 59.7 bits (138), Expect = 1e-08
Identities = 49/160 (30%), Positives = 74/160 (46%), Gaps = 14/160 (8%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG-----------KRSYLRACIKEAMR 434
G DTT++ +S LY +A + Q++ REE+ S G + Y CIKEA+R
Sbjct: 322 GHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALR 381
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V G R + G +P+ + + + L K +P P F P R+ +
Sbjct: 382 LYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSA 441
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIA--ELEVETFLS 143
H A PF G R+CIG++ A EL+V T L+
Sbjct: 442 Q-------HSHAFLPFSGGSRNCIGKQFAMNELKVATALT 474
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 59.7 bits (138), Expect = 1e-08
Identities = 49/160 (30%), Positives = 74/160 (46%), Gaps = 14/160 (8%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG-----------KRSYLRACIKEAMR 434
G DTT++ +S LY +A + Q++ REE+ S G + Y CIKEA+R
Sbjct: 322 GHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALR 381
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V G R + G +P+ + + + L K +P P F P R+ +
Sbjct: 382 LYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSA 441
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIA--ELEVETFLS 143
H A PF G R+CIG++ A EL+V T L+
Sbjct: 442 Q-------HSHAFLPFSGGSRNCIGKQFAMNELKVATALT 474
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 59.7 bits (138), Expect = 1e-08
Identities = 43/179 (24%), Positives = 84/179 (46%), Gaps = 12/179 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE---VMSKN--------GKRSYLRACI 449
++ +AG +T S T+ L+ + + + K+ EE V+ KN K Y+ A I
Sbjct: 297 NLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVI 356
Query: 448 KEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
E R V+ ++ RR K+ + +P+ ++ + ++ P +F P+ +
Sbjct: 357 HEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHF 416
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWSGSSPR 95
L +K + + F PF G R C G +A +E+ F + +++NF+++ S SP+
Sbjct: 417 LDDKGQ---FKKSDAFV--PFSIGKRYCFGEGLARMELFLFFTTVMQNFRLK-SSQSPK 469
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 12/179 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGK--------- 473
+EE D+ AG +TTS T+ L MA+ + Q+K++ E+ G+
Sbjct: 297 HEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAAR 356
Query: 472 --RSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R+ ++ N+ R T + + GYH+P+ I L +
Sbjct: 357 ESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWA 416
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
P F P+ +L N + F PF G R+C+G ++A E+ F + +++ F
Sbjct: 417 TPDTFNPDHFLENGQ----FKKREAF--MPFSIGKRACLGEQLARTELFIFFTSLMQKF 469
>BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family
51, subfamily A, polypeptide 1 protein.
Length = 509
Score = 59.7 bits (138), Expect = 1e-08
Identities = 60/256 (23%), Positives = 114/256 (44%), Gaps = 21/256 (8%)
Frame = -2
Query: 781 YVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLD--------I 626
++ P FR+ + + E +++ KA+ + ++ K DD +L+ LLD +
Sbjct: 250 WLPLPSFRRRDRAHREIKDI----FYKAIQKRRQSQEKIDD---ILQTLLDATYKDGRPL 302
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKR-------- 470
++ M +L+AG T+S T + + +A ++ Q+K E + G+
Sbjct: 303 TDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQ 362
Query: 469 ----SYLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
+ L CIKE +R+ P V MR + GY IP + + ++ +
Sbjct: 363 LKDLNLLDRCIKETLRLRPPVMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWV 422
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+F P+R+L + +P + FA PFG G CIG A ++++T S ++ ++
Sbjct: 423 ERLDFNPDRYL--QDNP---ASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYE 477
Query: 121 VEW-SGSSPRVEQTSI 77
+ G P V T++
Sbjct: 478 FDLIDGYFPTVNYTTM 493
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 12/179 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGK--------- 473
+EE D+ AG +TTS T+ L MA+ + Q+K++ E+ G+
Sbjct: 297 HEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAAR 356
Query: 472 --RSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R+ ++ N+ R T + + GYH+P+ I L +
Sbjct: 357 ESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWA 416
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
P F P+ +L N + F PF G R+C+G ++A E+ F + +++ F
Sbjct: 417 TPDTFNPDHFLENGQ----FKKREAF--MPFSIGKRACLGEQLARTELFIFFTSLMQKF 469
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 59.7 bits (138), Expect = 1e-08
Identities = 49/160 (30%), Positives = 74/160 (46%), Gaps = 14/160 (8%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG-----------KRSYLRACIKEAMR 434
G DTT++ +S LY +A + Q++ REE+ S G + Y CIKEA+R
Sbjct: 322 GHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALR 381
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V G R + G +P+ + + + L K +P P F P R+ +
Sbjct: 382 LYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSA 441
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIA--ELEVETFLS 143
H A PF G R+CIG++ A EL+V T L+
Sbjct: 442 Q-------HSHAFLPFSGGSRNCIGKQFAMNELKVATALT 474
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 59.7 bits (138), Expect = 1e-08
Identities = 49/160 (30%), Positives = 74/160 (46%), Gaps = 14/160 (8%)
Frame = -2
Query: 580 GVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNG-----------KRSYLRACIKEAMR 434
G DTT++ +S LY +A + Q++ REE+ S G + Y CIKEA+R
Sbjct: 322 GHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALR 381
Query: 433 ILPVVSGNMRRTTKEYNIL-GYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKS 257
+ P V G R + G +P+ + + + L K +P P F P R+ +
Sbjct: 382 LYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSA 441
Query: 256 DPLYYGNAHPFANSPFGFGVRSCIGRRIA--ELEVETFLS 143
H A PF G R+CIG++ A EL+V T L+
Sbjct: 442 Q-------HSHAFLPFSGGSRNCIGKQFAMNELKVATALT 474
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 59.7 bits (138), Expect = 1e-08
Identities = 46/179 (25%), Positives = 78/179 (43%), Gaps = 12/179 (6%)
Frame = -2
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGK--------- 473
+EE D+ AG +TTS T+ L MA+ + Q+K++ E+ G+
Sbjct: 297 HEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAAR 356
Query: 472 --RSYLRACIKEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
Y A I E R+ ++ N+ R T + + GYH+P+ I L +
Sbjct: 357 ESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWA 416
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENF 125
P F P+ +L N + F PF G R+C+G ++A E+ F + +++ F
Sbjct: 417 TPDTFNPDHFLENGQ----FKKREAF--MPFSIGKRACLGEQLARTELFIFFTSLMQKF 469
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/179 (23%), Positives = 83/179 (46%), Gaps = 12/179 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE---VMSKN--------GKRSYLRACI 449
++ + G +T S T+ L+ + + + K+ EE V+ KN K Y+ A I
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVI 356
Query: 448 KEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
E R V+ ++ RR K+ + +P+ ++ + ++ P +F P+ +
Sbjct: 357 HEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHF 416
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWSGSSPR 95
L K + + F PF G R+C G +A +E+ F + +++NF+++ S SP+
Sbjct: 417 LNEKGQ---FKKSDAFV--PFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-SSQSPK 469
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/179 (23%), Positives = 83/179 (46%), Gaps = 12/179 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE---VMSKN--------GKRSYLRACI 449
++ + G +T S T+ L+ + + + K+ EE V+ KN K Y+ A I
Sbjct: 251 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVI 310
Query: 448 KEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
E R V+ ++ RR K+ + +P+ ++ + ++ P +F P+ +
Sbjct: 311 HEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHF 370
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWSGSSPR 95
L K + + F PF G R+C G +A +E+ F + +++NF+++ S SP+
Sbjct: 371 LNEKGQ---FKKSDAFV--PFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-SSQSPK 423
>U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase
cytochrome P450 protein.
Length = 509
Score = 59.3 bits (137), Expect = 2e-08
Identities = 59/256 (23%), Positives = 114/256 (44%), Gaps = 21/256 (8%)
Frame = -2
Query: 781 YVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLD--------I 626
++ P FR+ + + E +++ KA+ + ++ K DD +L+ LLD +
Sbjct: 250 WLPLPSFRRRDRAHREIKDI----FYKAIQKRRQSQEKIDD---ILQTLLDATYKDGRPL 302
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKR-------- 470
++ M +L+AG T+S T + + +A ++ Q+K E + G+
Sbjct: 303 TDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQ 362
Query: 469 ----SYLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
+ L CIKE +R+ P + MR + GY IP + + ++ +
Sbjct: 363 LKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWV 422
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+F P+R+L + +P + FA PFG G CIG A ++++T S ++ ++
Sbjct: 423 ERLDFNPDRYL--QDNP---ASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYE 477
Query: 121 VEW-SGSSPRVEQTSI 77
+ G P V T++
Sbjct: 478 FDLIDGYFPTVNYTTM 493
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/179 (23%), Positives = 83/179 (46%), Gaps = 12/179 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE---VMSKN--------GKRSYLRACI 449
++ + G +T S T+ L+ + + + K+ EE V+ KN K Y+ A I
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVI 356
Query: 448 KEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
E R V+ ++ RR K+ + +P+ ++ + ++ P +F P+ +
Sbjct: 357 HEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHF 416
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWSGSSPR 95
L K + + F PF G R+C G +A +E+ F + +++NF+++ S SP+
Sbjct: 417 LNEKGQ---FKKSDAFV--PFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-SSQSPK 469
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 59.3 bits (137), Expect = 2e-08
Identities = 43/184 (23%), Positives = 86/184 (46%), Gaps = 12/184 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE---VMSKNG--------KRSYLRACI 449
++ +AG +T S T+ L+ + + + K+ EE V+ KN K Y+ A I
Sbjct: 297 NLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVI 356
Query: 448 KEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
E R V+ ++ RR K+ + +P+ ++ + ++ P +F P+ +
Sbjct: 357 HEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHF 416
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWSGSSPRV 92
L +K + + F PF G R C G +A +E+ F + +++NF+++ S S +
Sbjct: 417 LDDKGQ---FKKSDAFV--PFSIGKRYCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDI 471
Query: 91 EQTS 80
+ +S
Sbjct: 472 DVSS 475
>D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase
protein.
Length = 509
Score = 59.3 bits (137), Expect = 2e-08
Identities = 59/256 (23%), Positives = 114/256 (44%), Gaps = 21/256 (8%)
Frame = -2
Query: 781 YVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLD--------I 626
++ P FR+ + + E +++ KA+ + ++ K DD +L+ LLD +
Sbjct: 250 WLPLPSFRRRDRAHREIKDI----FYKAIQKRRQSQEKIDD---ILQTLLDATYKDGRPL 302
Query: 625 NEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKR-------- 470
++ M +L+AG T+S T + + +A ++ Q+K E + G+
Sbjct: 303 TDDEVAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTVCGENLPPLTYDQ 362
Query: 469 ----SYLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYP 302
+ L CIKE +R+ P + MR + GY IP + + ++ +
Sbjct: 363 LKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWV 422
Query: 301 RPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQ 122
+F P+R+L + +P + FA PFG G CIG A ++++T S ++ ++
Sbjct: 423 ERLDFNPDRYL--QDNP---ASGEKFAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYE 477
Query: 121 VEW-SGSSPRVEQTSI 77
+ G P V T++
Sbjct: 478 FDLIDGYFPTVNYTTM 493
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/179 (23%), Positives = 83/179 (46%), Gaps = 12/179 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE---VMSKN--------GKRSYLRACI 449
++ + G +T S T+ L+ + + + K+ EE V+ KN K Y+ A I
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVI 356
Query: 448 KEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
E R V+ ++ RR K+ + +P+ ++ + ++ P +F P+ +
Sbjct: 357 HEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHF 416
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWSGSSPR 95
L K + + F PF G R+C G +A +E+ F + +++NF+++ S SP+
Sbjct: 417 LNEKGQ---FKKSDAFV--PFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-SSQSPK 469
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/179 (23%), Positives = 83/179 (46%), Gaps = 12/179 (6%)
Frame = -2
Query: 595 DMLVAGVDTTSNTMSATLYLMAINQDKQQKLREE---VMSKN--------GKRSYLRACI 449
++ + G +T S T+ L+ + + + K+ EE V+ KN K Y+ A I
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVI 356
Query: 448 KEAMRILPVVSGNM-RRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERW 272
E R V+ ++ RR K+ + +P+ ++ + ++ P +F P+ +
Sbjct: 357 HEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHF 416
Query: 271 LTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWSGSSPR 95
L K + + F PF G R+C G +A +E+ F + +++NF+++ S SP+
Sbjct: 417 LNEKGQ---FKKSDAFV--PFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-SSQSPK 469
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 122,921,137
Number of Sequences: 237096
Number of extensions: 2715945
Number of successful extensions: 8027
Number of sequences better than 10.0: 449
Number of HSP's better than 10.0 without gapping: 7118
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7512
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 11039988564
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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