Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmmt13m22
(696 letters)
Database: bee
438 sequences; 146,343 total letters
Searching......................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z26319-1|CAA81228.1| 464|Apis mellifera royal jelly protein RJP... 27 0.17
AY569694-1|AAS86647.1| 400|Apis mellifera complementary sex det... 26 0.39
AY127579-1|AAN02286.1| 405|Apis mellifera venom protease precur... 26 0.39
DQ325082-1|ABD14096.1| 179|Apis mellifera complementary sex det... 24 1.2
DQ325077-1|ABD14091.1| 181|Apis mellifera complementary sex det... 24 1.2
DQ325133-1|ABD14147.1| 181|Apis mellifera complementary sex det... 23 2.1
DQ325076-1|ABD14090.1| 191|Apis mellifera complementary sex det... 23 2.1
DQ325075-1|ABD14089.1| 181|Apis mellifera complementary sex det... 23 2.1
DQ325074-1|ABD14088.1| 181|Apis mellifera complementary sex det... 23 2.1
DQ325073-1|ABD14087.1| 181|Apis mellifera complementary sex det... 23 2.1
DQ325072-1|ABD14086.1| 181|Apis mellifera complementary sex det... 23 2.1
DQ325071-1|ABD14085.1| 181|Apis mellifera complementary sex det... 23 2.1
DQ325070-1|ABD14084.1| 181|Apis mellifera complementary sex det... 23 2.1
DQ325069-1|ABD14083.1| 181|Apis mellifera complementary sex det... 23 2.1
DQ325068-1|ABD14082.1| 181|Apis mellifera complementary sex det... 23 2.1
AY569696-1|AAS86649.1| 414|Apis mellifera complementary sex det... 23 2.1
AY569695-1|AAS86648.1| 414|Apis mellifera complementary sex det... 23 2.1
DQ325102-1|ABD14116.1| 183|Apis mellifera complementary sex det... 23 3.7
DQ325101-1|ABD14115.1| 182|Apis mellifera complementary sex det... 23 3.7
DQ325100-1|ABD14114.1| 183|Apis mellifera complementary sex det... 23 3.7
DQ325099-1|ABD14113.1| 183|Apis mellifera complementary sex det... 23 3.7
DQ325098-1|ABD14112.1| 183|Apis mellifera complementary sex det... 23 3.7
DQ325097-1|ABD14111.1| 183|Apis mellifera complementary sex det... 23 3.7
DQ325096-1|ABD14110.1| 183|Apis mellifera complementary sex det... 23 3.7
DQ325095-1|ABD14109.1| 183|Apis mellifera complementary sex det... 23 3.7
EF127805-1|ABL67942.1| 461|Apis mellifera nicotinic acetylcholi... 22 4.8
EF127804-1|ABL67941.1| 461|Apis mellifera nicotinic acetylcholi... 22 4.8
EF127803-1|ABL67940.1| 461|Apis mellifera nicotinic acetylcholi... 22 4.8
EF127802-1|ABL67939.1| 461|Apis mellifera nicotinic acetylcholi... 22 4.8
EF127801-1|ABL67938.1| 461|Apis mellifera nicotinic acetylcholi... 22 4.8
EF127800-1|ABL67937.1| 461|Apis mellifera nicotinic acetylcholi... 22 4.8
DQ026036-1|AAY87895.1| 529|Apis mellifera nicotinic acetylcholi... 22 4.8
DQ026035-1|AAY87894.1| 529|Apis mellifera nicotinic acetylcholi... 22 4.8
AY569721-1|AAS86674.1| 400|Apis mellifera complementary sex det... 22 4.8
AY500239-1|AAR92109.1| 555|Apis mellifera neuronal nicotinic ac... 22 4.8
AB013288-1|BAA87894.1| 149|Apis mellifera protein kinase C prot... 22 4.8
AY569717-1|AAS86670.1| 397|Apis mellifera complementary sex det... 22 6.4
AY569712-1|AAS86665.1| 408|Apis mellifera complementary sex det... 22 6.4
DQ325115-1|ABD14129.1| 185|Apis mellifera complementary sex det... 21 8.5
DQ325080-1|ABD14094.1| 184|Apis mellifera complementary sex det... 21 8.5
DQ325079-1|ABD14093.1| 184|Apis mellifera complementary sex det... 21 8.5
DQ325078-1|ABD14092.1| 184|Apis mellifera complementary sex det... 21 8.5
DQ011226-1|AAY63895.1| 471|Apis mellifera Rh-like protein protein. 21 8.5
>Z26319-1|CAA81228.1| 464|Apis mellifera royal jelly protein
RJP57-2 protein.
Length = 464
Score = 27.1 bits (57), Expect = 0.17
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +1
Query: 112 IKNEHCKSFTNLNKLYFNFNHKENLFSS 195
I+N C +F N + ++N NH + SS
Sbjct: 409 IRNSRCANFDNQDNNHYNHNHNQARHSS 436
>AY569694-1|AAS86647.1| 400|Apis mellifera complementary sex
determiner protein.
Length = 400
Score = 25.8 bits (54), Expect = 0.39
Identities = 13/37 (35%), Positives = 20/37 (54%)
Frame = +1
Query: 76 PAMESKLKIKTQIKNEHCKSFTNLNKLYFNFNHKENL 186
P + S L KT N + ++ N KLY+N N+ E +
Sbjct: 301 PKIISSLSNKTIHNNNNYNNYNN-KKLYYNINYIEQI 336
>AY127579-1|AAN02286.1| 405|Apis mellifera venom protease precursor
protein.
Length = 405
Score = 25.8 bits (54), Expect = 0.39
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 3/42 (7%)
Frame = +1
Query: 106 TQIKNEHCKSFTNLN--KLYFNFNHKENL-FSSSLFYYTLPS 222
TQ+ E C + NLN ++Y+ +N + L +S S +T+ S
Sbjct: 35 TQVNKEECDYYQNLNLGEIYYIYNPRYPLPYSGSKCTWTITS 76
>DQ325082-1|ABD14096.1| 179|Apis mellifera complementary sex
determiner protein.
Length = 179
Score = 24.2 bits (50), Expect = 1.2
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Frame = +1
Query: 76 PAMESKLKIKTQIKNEHCKSFTNLN--KLYFNFNHKENLFSSSLFYY 210
P + S L KT N + K N N KLY+N N+ E + YY
Sbjct: 79 PKIISSLSNKTIHNNNNYKYNYNNNCKKLYYNINYIEQIPIPVPVYY 125
>DQ325077-1|ABD14091.1| 181|Apis mellifera complementary sex
determiner protein.
Length = 181
Score = 24.2 bits (50), Expect = 1.2
Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 2/39 (5%)
Frame = +1
Query: 76 PAMESKLKIKTQIKNEHCKS--FTNLNKLYFNFNHKENL 186
P + S L KT N + + + N KLY+N N+ E +
Sbjct: 79 PKIISSLSNKTIHNNNNYNNNNYNNYKKLYYNINYIEQV 117
>DQ325133-1|ABD14147.1| 181|Apis mellifera complementary sex
determiner protein.
Length = 181
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +1
Query: 142 NLNKLYFNFNHKENL 186
N NKLY+N N+ E +
Sbjct: 105 NYNKLYYNINYIEQI 119
>DQ325076-1|ABD14090.1| 191|Apis mellifera complementary sex
determiner protein.
Length = 191
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/23 (34%), Positives = 14/23 (60%)
Frame = +1
Query: 118 NEHCKSFTNLNKLYFNFNHKENL 186
N + ++ N KLY+N N+ E +
Sbjct: 105 NYNNNNYNNYKKLYYNINYIEQI 127
>DQ325075-1|ABD14089.1| 181|Apis mellifera complementary sex
determiner protein.
Length = 181
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +1
Query: 142 NLNKLYFNFNHKENL 186
N NKLY+N N+ E +
Sbjct: 105 NYNKLYYNINYIEQI 119
>DQ325074-1|ABD14088.1| 181|Apis mellifera complementary sex
determiner protein.
Length = 181
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +1
Query: 142 NLNKLYFNFNHKENL 186
N NKLY+N N+ E +
Sbjct: 105 NYNKLYYNINYIEQI 119
>DQ325073-1|ABD14087.1| 181|Apis mellifera complementary sex
determiner protein.
Length = 181
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +1
Query: 142 NLNKLYFNFNHKENL 186
N NKLY+N N+ E +
Sbjct: 105 NYNKLYYNINYIEQI 119
>DQ325072-1|ABD14086.1| 181|Apis mellifera complementary sex
determiner protein.
Length = 181
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +1
Query: 142 NLNKLYFNFNHKENL 186
N NKLY+N N+ E +
Sbjct: 105 NYNKLYYNINYIEQI 119
>DQ325071-1|ABD14085.1| 181|Apis mellifera complementary sex
determiner protein.
Length = 181
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +1
Query: 142 NLNKLYFNFNHKENL 186
N NKLY+N N+ E +
Sbjct: 105 NYNKLYYNINYIEQI 119
>DQ325070-1|ABD14084.1| 181|Apis mellifera complementary sex
determiner protein.
Length = 181
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +1
Query: 142 NLNKLYFNFNHKENL 186
N NKLY+N N+ E +
Sbjct: 105 NYNKLYYNINYIEQI 119
>DQ325069-1|ABD14083.1| 181|Apis mellifera complementary sex
determiner protein.
Length = 181
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +1
Query: 142 NLNKLYFNFNHKENL 186
N NKLY+N N+ E +
Sbjct: 105 NYNKLYYNINYIEQI 119
>DQ325068-1|ABD14082.1| 181|Apis mellifera complementary sex
determiner protein.
Length = 181
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +1
Query: 142 NLNKLYFNFNHKENL 186
N NKLY+N N+ E +
Sbjct: 105 NYNKLYYNINYIEQI 119
>AY569696-1|AAS86649.1| 414|Apis mellifera complementary sex
determiner protein.
Length = 414
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +1
Query: 142 NLNKLYFNFNHKENL 186
N NKLY+N N+ E +
Sbjct: 338 NYNKLYYNINYIEQI 352
>AY569695-1|AAS86648.1| 414|Apis mellifera complementary sex
determiner protein.
Length = 414
Score = 23.4 bits (48), Expect = 2.1
Identities = 8/15 (53%), Positives = 11/15 (73%)
Frame = +1
Query: 142 NLNKLYFNFNHKENL 186
N NKLY+N N+ E +
Sbjct: 338 NYNKLYYNINYIEQI 352
>DQ325102-1|ABD14116.1| 183|Apis mellifera complementary sex
determiner protein.
Length = 183
Score = 22.6 bits (46), Expect = 3.7
Identities = 7/18 (38%), Positives = 12/18 (66%)
Frame = +1
Query: 133 SFTNLNKLYFNFNHKENL 186
++ N KLY+N N+ E +
Sbjct: 102 NYNNYKKLYYNINYIEQI 119
>DQ325101-1|ABD14115.1| 182|Apis mellifera complementary sex
determiner protein.
Length = 182
Score = 22.6 bits (46), Expect = 3.7
Identities = 7/18 (38%), Positives = 12/18 (66%)
Frame = +1
Query: 133 SFTNLNKLYFNFNHKENL 186
++ N KLY+N N+ E +
Sbjct: 102 NYNNYKKLYYNINYIEQI 119
>DQ325100-1|ABD14114.1| 183|Apis mellifera complementary sex
determiner protein.
Length = 183
Score = 22.6 bits (46), Expect = 3.7
Identities = 7/18 (38%), Positives = 12/18 (66%)
Frame = +1
Query: 133 SFTNLNKLYFNFNHKENL 186
++ N KLY+N N+ E +
Sbjct: 102 NYNNYKKLYYNINYIEQI 119
>DQ325099-1|ABD14113.1| 183|Apis mellifera complementary sex
determiner protein.
Length = 183
Score = 22.6 bits (46), Expect = 3.7
Identities = 7/18 (38%), Positives = 12/18 (66%)
Frame = +1
Query: 133 SFTNLNKLYFNFNHKENL 186
++ N KLY+N N+ E +
Sbjct: 102 NYNNYKKLYYNINYIEQI 119
>DQ325098-1|ABD14112.1| 183|Apis mellifera complementary sex
determiner protein.
Length = 183
Score = 22.6 bits (46), Expect = 3.7
Identities = 7/18 (38%), Positives = 12/18 (66%)
Frame = +1
Query: 133 SFTNLNKLYFNFNHKENL 186
++ N KLY+N N+ E +
Sbjct: 102 NYNNYKKLYYNINYIEQI 119
>DQ325097-1|ABD14111.1| 183|Apis mellifera complementary sex
determiner protein.
Length = 183
Score = 22.6 bits (46), Expect = 3.7
Identities = 7/18 (38%), Positives = 12/18 (66%)
Frame = +1
Query: 133 SFTNLNKLYFNFNHKENL 186
++ N KLY+N N+ E +
Sbjct: 102 NYNNYKKLYYNINYIEQI 119
>DQ325096-1|ABD14110.1| 183|Apis mellifera complementary sex
determiner protein.
Length = 183
Score = 22.6 bits (46), Expect = 3.7
Identities = 7/18 (38%), Positives = 12/18 (66%)
Frame = +1
Query: 133 SFTNLNKLYFNFNHKENL 186
++ N KLY+N N+ E +
Sbjct: 102 NYNNYKKLYYNINYIEQI 119
>DQ325095-1|ABD14109.1| 183|Apis mellifera complementary sex
determiner protein.
Length = 183
Score = 22.6 bits (46), Expect = 3.7
Identities = 7/18 (38%), Positives = 12/18 (66%)
Frame = +1
Query: 133 SFTNLNKLYFNFNHKENL 186
++ N KLY+N N+ E +
Sbjct: 102 NYNNYKKLYYNINYIEQI 119
>EF127805-1|ABL67942.1| 461|Apis mellifera nicotinic acetylcholine
receptor subunitalpha 6 transcript variant 6 protein.
Length = 461
Score = 22.2 bits (45), Expect = 4.8
Identities = 6/11 (54%), Positives = 10/11 (90%)
Frame = +2
Query: 617 IYFFYCLIIPC 649
+Y+F+ LI+PC
Sbjct: 195 LYYFFNLIVPC 205
>EF127804-1|ABL67941.1| 461|Apis mellifera nicotinic acetylcholine
receptor subunitalpha 6 transcript variant 5 protein.
Length = 461
Score = 22.2 bits (45), Expect = 4.8
Identities = 6/11 (54%), Positives = 10/11 (90%)
Frame = +2
Query: 617 IYFFYCLIIPC 649
+Y+F+ LI+PC
Sbjct: 195 LYYFFNLIVPC 205
>EF127803-1|ABL67940.1| 461|Apis mellifera nicotinic acetylcholine
receptor subunitalpha 6 transcript variant 4 protein.
Length = 461
Score = 22.2 bits (45), Expect = 4.8
Identities = 6/11 (54%), Positives = 10/11 (90%)
Frame = +2
Query: 617 IYFFYCLIIPC 649
+Y+F+ LI+PC
Sbjct: 195 LYYFFNLIVPC 205
>EF127802-1|ABL67939.1| 461|Apis mellifera nicotinic acetylcholine
receptor subunitalpha 6 transcript variant 3 protein.
Length = 461
Score = 22.2 bits (45), Expect = 4.8
Identities = 6/11 (54%), Positives = 10/11 (90%)
Frame = +2
Query: 617 IYFFYCLIIPC 649
+Y+F+ LI+PC
Sbjct: 195 LYYFFNLIVPC 205
>EF127801-1|ABL67938.1| 461|Apis mellifera nicotinic acetylcholine
receptor subunitalpha 6 transcript variant 2 protein.
Length = 461
Score = 22.2 bits (45), Expect = 4.8
Identities = 6/11 (54%), Positives = 10/11 (90%)
Frame = +2
Query: 617 IYFFYCLIIPC 649
+Y+F+ LI+PC
Sbjct: 195 LYYFFNLIVPC 205
>EF127800-1|ABL67937.1| 461|Apis mellifera nicotinic acetylcholine
receptor subunitalpha 6 transcript variant 1 protein.
Length = 461
Score = 22.2 bits (45), Expect = 4.8
Identities = 6/11 (54%), Positives = 10/11 (90%)
Frame = +2
Query: 617 IYFFYCLIIPC 649
+Y+F+ LI+PC
Sbjct: 195 LYYFFNLIVPC 205
>DQ026036-1|AAY87895.1| 529|Apis mellifera nicotinic acetylcholine
receptor alpha6subunit protein.
Length = 529
Score = 22.2 bits (45), Expect = 4.8
Identities = 6/11 (54%), Positives = 10/11 (90%)
Frame = +2
Query: 617 IYFFYCLIIPC 649
+Y+F+ LI+PC
Sbjct: 263 LYYFFNLIVPC 273
>DQ026035-1|AAY87894.1| 529|Apis mellifera nicotinic acetylcholine
receptor alpha6subunit protein.
Length = 529
Score = 22.2 bits (45), Expect = 4.8
Identities = 6/11 (54%), Positives = 10/11 (90%)
Frame = +2
Query: 617 IYFFYCLIIPC 649
+Y+F+ LI+PC
Sbjct: 263 LYYFFNLIVPC 273
>AY569721-1|AAS86674.1| 400|Apis mellifera complementary sex
determiner protein.
Length = 400
Score = 22.2 bits (45), Expect = 4.8
Identities = 11/37 (29%), Positives = 17/37 (45%)
Frame = +1
Query: 76 PAMESKLKIKTQIKNEHCKSFTNLNKLYFNFNHKENL 186
P + S L N + + N KLY+N N+ E +
Sbjct: 301 PKIISSLSNSCNYSNNYYNN-NNYKKLYYNINYIEQI 336
>AY500239-1|AAR92109.1| 555|Apis mellifera neuronal nicotinic
acetylcholine receptoralpha7-1 protein.
Length = 555
Score = 22.2 bits (45), Expect = 4.8
Identities = 6/11 (54%), Positives = 10/11 (90%)
Frame = +2
Query: 617 IYFFYCLIIPC 649
+Y+F+ LI+PC
Sbjct: 232 LYYFFNLIVPC 242
>AB013288-1|BAA87894.1| 149|Apis mellifera protein kinase C
protein.
Length = 149
Score = 22.2 bits (45), Expect = 4.8
Identities = 7/16 (43%), Positives = 12/16 (75%)
Frame = +2
Query: 191 VHHCFITLCRLFYIEE 238
+H CF T+ RL+++ E
Sbjct: 50 LHSCFQTMDRLYFVME 65
>AY569717-1|AAS86670.1| 397|Apis mellifera complementary sex
determiner protein.
Length = 397
Score = 21.8 bits (44), Expect = 6.4
Identities = 9/43 (20%), Positives = 21/43 (48%)
Frame = +1
Query: 88 SKLKIKTQIKNEHCKSFTNLNKLYFNFNHKENLFSSSLFYYTL 216
SK + + + + E K ++ +N+ + N ++S YY +
Sbjct: 285 SKGRSRDRTERERSKETKIISSNNYNYKNYNNNYNSKKLYYNI 327
>AY569712-1|AAS86665.1| 408|Apis mellifera complementary sex
determiner protein.
Length = 408
Score = 21.8 bits (44), Expect = 6.4
Identities = 9/43 (20%), Positives = 21/43 (48%)
Frame = +1
Query: 88 SKLKIKTQIKNEHCKSFTNLNKLYFNFNHKENLFSSSLFYYTL 216
SK + + + + E K ++ +N+ + N ++S YY +
Sbjct: 296 SKGRSRDRTERERSKETKIISSNNYNYKNYNNNYNSKKLYYNI 338
>DQ325115-1|ABD14129.1| 185|Apis mellifera complementary sex
determiner protein.
Length = 185
Score = 21.4 bits (43), Expect = 8.5
Identities = 9/25 (36%), Positives = 12/25 (48%)
Frame = +1
Query: 142 NLNKLYFNFNHKENLFSSSLFYYTL 216
N N Y N+N+ N L YY +
Sbjct: 93 NYNNNYNNYNNNYNTNYKKLQYYNI 117
>DQ325080-1|ABD14094.1| 184|Apis mellifera complementary sex
determiner protein.
Length = 184
Score = 21.4 bits (43), Expect = 8.5
Identities = 9/23 (39%), Positives = 12/23 (52%)
Frame = +1
Query: 142 NLNKLYFNFNHKENLFSSSLFYY 210
N KLY+N N+ E + YY
Sbjct: 108 NCKKLYYNINYIEQIPIPVPVYY 130
>DQ325079-1|ABD14093.1| 184|Apis mellifera complementary sex
determiner protein.
Length = 184
Score = 21.4 bits (43), Expect = 8.5
Identities = 9/23 (39%), Positives = 12/23 (52%)
Frame = +1
Query: 142 NLNKLYFNFNHKENLFSSSLFYY 210
N KLY+N N+ E + YY
Sbjct: 108 NCKKLYYNINYIEQIPIPVPVYY 130
>DQ325078-1|ABD14092.1| 184|Apis mellifera complementary sex
determiner protein.
Length = 184
Score = 21.4 bits (43), Expect = 8.5
Identities = 9/23 (39%), Positives = 12/23 (52%)
Frame = +1
Query: 142 NLNKLYFNFNHKENLFSSSLFYY 210
N KLY+N N+ E + YY
Sbjct: 108 NCKKLYYNINYIEQIPIPVPVYY 130
>DQ011226-1|AAY63895.1| 471|Apis mellifera Rh-like protein protein.
Length = 471
Score = 21.4 bits (43), Expect = 8.5
Identities = 10/23 (43%), Positives = 14/23 (60%)
Frame = +3
Query: 312 ISFVLSLNQKIHVHNLVFVSYHS 380
ISFV + +K H+L SY+S
Sbjct: 187 ISFVFGMKEKRKEHHLEGPSYNS 209
Database: bee
Posted date: Oct 23, 2007 1:17 PM
Number of letters in database: 146,343
Number of sequences in database: 438
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 161,063
Number of Sequences: 438
Number of extensions: 3130
Number of successful extensions: 48
Number of sequences better than 10.0: 43
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 48
length of database: 146,343
effective HSP length: 56
effective length of database: 121,815
effective search space used: 21317625
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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