Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmmt13h18
(675 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 276 6e-74
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 276 6e-74
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 276 6e-74
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 276 6e-74
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 276 6e-74
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 276 6e-74
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 274 1e-73
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 273 4e-73
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 270 2e-72
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 262 1e-69
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 239 6e-63
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 238 1e-62
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 238 1e-62
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 238 1e-62
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 238 1e-62
AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitra... 128 2e-29
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 276 bits (676), Expect = 6e-74
Identities = 127/156 (81%), Positives = 138/156 (88%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 245 LAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 138
LA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
Score = 34.3 bits (75), Expect = 0.40
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 276 bits (676), Expect = 6e-74
Identities = 127/156 (81%), Positives = 138/156 (88%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 245 LAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 138
LA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
Score = 34.3 bits (75), Expect = 0.40
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 276 bits (676), Expect = 6e-74
Identities = 127/156 (81%), Positives = 138/156 (88%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 245 LAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 138
LA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
Score = 34.3 bits (75), Expect = 0.40
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 276 bits (676), Expect = 6e-74
Identities = 127/156 (81%), Positives = 138/156 (88%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 245 LAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 138
LA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
Score = 34.3 bits (75), Expect = 0.40
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 276 bits (676), Expect = 6e-74
Identities = 127/156 (81%), Positives = 138/156 (88%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 245 LAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 138
LA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
Score = 34.3 bits (75), Expect = 0.40
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 276 bits (676), Expect = 6e-74
Identities = 127/156 (81%), Positives = 138/156 (88%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 245 LAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 138
LA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
Score = 34.3 bits (75), Expect = 0.40
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 274 bits (673), Expect = 1e-73
Identities = 126/156 (80%), Positives = 138/156 (88%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAE+AHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAESAHGTVTRH 315
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 245 LAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 138
LA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
Score = 34.3 bits (75), Expect = 0.40
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 273 bits (669), Expect = 4e-73
Identities = 126/156 (80%), Positives = 137/156 (87%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTK
Sbjct: 316 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKG 375
Query: 245 LAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 138
LA CIKG+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 376 LAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
Score = 34.3 bits (75), Expect = 0.40
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 270 bits (663), Expect = 2e-72
Identities = 125/156 (80%), Positives = 137/156 (87%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 256 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 315
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R YQ+G+ETSTN IASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 316 YRMYQKGQETSTNLIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 375
Query: 245 LAICIKGMNNVKRSDYYETFEFMDKLAENLKVALGQ 138
LA CI+G+ NV+RSDY TFEFMDKL ENLK+ L Q
Sbjct: 376 LAACIRGLPNVQRSDYLNTFEFMDKLGENLKIKLAQ 411
Score = 34.3 bits (75), Expect = 0.40
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 244 IWYEHRLIDDMVAQAMKSEGGFIWAC 269
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 262 bits (641), Expect = 1e-69
Identities = 120/145 (82%), Positives = 130/145 (89%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A AMKSEGGF+WACKNYDGDVQSDSVAQGYGSLG+MTSVL+CPDGKTVEAEAAHGTVTRH
Sbjct: 227 AQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDGKTVEAEAAHGTVTRH 286
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R YQ+G+ETSTNPIASIFAWTRGL HRAKLDNN L FA LE+V IETIE+G MTKD
Sbjct: 287 YRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALEEVSIETIEAGFMTKD 346
Query: 245 LAICIKGMNNVKRSDYYETFEFMDK 171
LA CIKG+ NV+RSDY TFEFMDK
Sbjct: 347 LAACIKGLPNVQRSDYLNTFEFMDK 371
Score = 34.3 bits (75), Expect = 0.40
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 215 IWYEHRLIDDMVAQAMKSEGGFIWAC 240
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 239 bits (585), Expect = 6e-63
Identities = 109/157 (69%), Positives = 131/157 (83%), Gaps = 1/157 (0%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A +KS GGFVWACKNYDGDVQSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH
Sbjct: 295 AQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRH 354
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKD
Sbjct: 355 YREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKD 414
Query: 245 LAICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 138
LA CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 415 LAGCIHGLSNVKLNEHFLNTMDFLDTIKSNLDRALGR 451
Score = 33.5 bits (73), Expect = 0.70
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 283 IWYEHRLIDDMVAQVLKSSGGFVWAC 308
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 238 bits (583), Expect = 1e-62
Identities = 109/157 (69%), Positives = 131/157 (83%), Gaps = 1/157 (0%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A +KS GGFVWACKNYDGDVQSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH
Sbjct: 262 AQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRH 321
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKD
Sbjct: 322 YREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKD 381
Query: 245 LAICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 138
LA CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 382 LAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 418
Score = 33.5 bits (73), Expect = 0.70
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 250 IWYEHRLIDDMVAQVLKSSGGFVWAC 275
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 238 bits (583), Expect = 1e-62
Identities = 109/157 (69%), Positives = 131/157 (83%), Gaps = 1/157 (0%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A +KS GGFVWACKNYDGDVQSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH
Sbjct: 295 AQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRH 354
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKD
Sbjct: 355 YREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKD 414
Query: 245 LAICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 138
LA CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 415 LAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
Score = 33.5 bits (73), Expect = 0.70
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 283 IWYEHRLIDDMVAQVLKSSGGFVWAC 308
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 238 bits (583), Expect = 1e-62
Identities = 109/157 (69%), Positives = 131/157 (83%), Gaps = 1/157 (0%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A +KS GGFVWACKNYDGDVQSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH
Sbjct: 295 AQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRH 354
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKD
Sbjct: 355 YREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKD 414
Query: 245 LAICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 138
LA CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 415 LAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
Score = 33.5 bits (73), Expect = 0.70
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 283 IWYEHRLIDDMVAQVLKSSGGFVWAC 308
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 238 bits (583), Expect = 1e-62
Identities = 109/157 (69%), Positives = 131/157 (83%), Gaps = 1/157 (0%)
Frame = -2
Query: 605 AYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLICPDGKTVEAEAAHGTVTRH 426
A +KS GGFVWACKNYDGDVQSD +AQG+GSLGLMTSVL+CPDGKT+EAEAAHGTVTRH
Sbjct: 295 AQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRH 354
Query: 425 FRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKD 246
+R +Q+G+ TSTNPIASIFAWTRGL HR KLD N L FA+ LEKVC+ET+ESG MTKD
Sbjct: 355 YREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAMTKD 414
Query: 245 LAICIKGMNNVKRSDYY-ETFEFMDKLAENLKVALGQ 138
LA CI G++NVK ++++ T +F+D + NL ALG+
Sbjct: 415 LAGCIHGLSNVKLNEHFLNTTDFLDTIKSNLDRALGR 451
Score = 33.5 bits (73), Expect = 0.70
Identities = 15/26 (57%), Positives = 16/26 (61%), Gaps = 3/26 (11%)
Frame = -1
Query: 642 IWYEHRLIDDMVGLCYEIRG---WIC 574
IWYEHRLIDDMV + G W C
Sbjct: 283 IWYEHRLIDDMVAQVLKSSGGFVWAC 308
>AF197566-1|AAG43470.1| 127|Homo sapiens NADP+-specific isocitrate
dehydrogenase protein.
Length = 127
Score = 128 bits (308), Expect = 2e-29
Identities = 61/89 (68%), Positives = 69/89 (77%)
Frame = -2
Query: 404 KETSTNPIASIFAWTRGLLHRAKLDNNDALKNFAETLEKVCIETIESGIMTKDLAICIKG 225
+E STNPIASIFAWTRGL RAK DNN L FA LE+VCIETIE+G MTKDLA CIKG
Sbjct: 1 QEISTNPIASIFAWTRGLALRAKTDNNKELAFFANALEEVCIETIEAGFMTKDLAACIKG 60
Query: 224 MNNVKRSDYYETFEFMDKLAENLKVALGQ 138
+ + + SDY TFEFM+KL ENLK+ L Q
Sbjct: 61 LPSAQCSDYLNTFEFMEKLGENLKIKLAQ 89
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,752,613
Number of Sequences: 237096
Number of extensions: 2097285
Number of successful extensions: 3024
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 2946
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3018
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7615267504
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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