Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmmt12p05
(644 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 218 2e-56
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 218 2e-56
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 218 2e-56
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 218 2e-56
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 218 2e-56
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 218 2e-56
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 218 2e-56
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 207 3e-53
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 207 3e-53
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 207 3e-53
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 207 3e-53
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 200 3e-51
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 200 3e-51
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 193 5e-49
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 193 5e-49
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 193 5e-49
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 193 5e-49
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 193 5e-49
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 169 1e-41
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 168 1e-41
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 168 1e-41
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 168 1e-41
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 168 1e-41
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 168 1e-41
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 168 1e-41
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 168 1e-41
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 167 2e-41
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 166 7e-41
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 164 2e-40
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 163 5e-40
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 161 1e-39
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 142 1e-33
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 142 1e-33
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 142 1e-33
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 142 1e-33
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 142 1e-33
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 142 1e-33
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 64 5e-10
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 64 5e-10
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 42 0.002
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 41 0.004
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 40 0.010
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 40 0.010
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 40 0.010
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 40 0.010
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 40 0.010
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 40 0.010
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 40 0.010
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 40 0.010
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 40 0.010
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 40 0.010
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 40 0.010
AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinog... 35 0.22
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.28
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.28
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.28
BC015008-1|AAH15008.1| 203|Homo sapiens HAGHL protein protein. 35 0.28
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 35 0.28
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 35 0.28
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 35 0.28
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 35 0.28
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 35 0.28
AB177847-1|BAD66825.1| 396|Homo sapiens KIAA1149 splice variant... 35 0.28
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 35 0.28
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 32 2.0
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 32 2.0
AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein. 31 2.7
U94332-1|AAB53709.1| 401|Homo sapiens osteoprotegerin protein. 31 3.5
BC030155-1|AAH30155.1| 401|Homo sapiens tumor necrosis factor r... 31 3.5
AY466112-1|AAR23265.1| 401|Homo sapiens tumor necrosis factor r... 31 3.5
AK223155-1|BAD96875.1| 401|Homo sapiens osteoprotegerin precurs... 31 3.5
AF134187-1|AAF20168.1| 372|Homo sapiens osteoprotegerin protein. 31 3.5
AB008822-1|BAA32076.1| 401|Homo sapiens osteoclastogenesis inhi... 31 3.5
AB002146-1|BAA25910.1| 401|Homo sapiens osteoclastogenesis inhi... 31 3.5
Z97652-2|CAM26431.1| 1269|Homo sapiens Crm, cramped-like (Drosop... 30 8.1
U52840-1|AAC09473.1| 1074|Homo sapiens semaphorin F homolog prot... 30 8.1
BC146661-1|AAI46662.1| 686|Homo sapiens STIM2 protein protein. 30 8.1
BC115696-1|AAI15697.1| 1074|Homo sapiens sema domain, seven thro... 30 8.1
AL031708-1|CAM26357.1| 1269|Homo sapiens Crm, cramped-like (Dros... 30 8.1
AL031009-1|CAM26477.1| 1269|Homo sapiens Crm, cramped-like (Dros... 30 8.1
AE006639-2|AAK61288.1| 1587|Homo sapiens unknown protein. 30 8.1
AB040915-1|BAA96006.1| 818|Homo sapiens KIAA1482 protein protein. 30 8.1
AB037847-1|BAA92664.2| 1066|Homo sapiens KIAA1426 protein protein. 30 8.1
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 218 bits (532), Expect = 2e-56
Identities = 101/210 (48%), Positives = 136/210 (64%), Gaps = 2/210 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
GMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G L
Sbjct: 200 GMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSL 259
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
+ + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 260 SYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVP 319
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P P
Sbjct: 320 LIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPS 379
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
GPLWILGDVFIG+YYT FD N ++GFA A
Sbjct: 380 GPLWILGDVFIGRYYTVFDRDNNRVGFAEA 409
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 218 bits (532), Expect = 2e-56
Identities = 101/210 (48%), Positives = 136/210 (64%), Gaps = 2/210 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
GMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G L
Sbjct: 200 GMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSL 259
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
+ + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 260 SYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVP 319
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P P
Sbjct: 320 LIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPS 379
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
GPLWILGDVFIG+YYT FD N ++GFA A
Sbjct: 380 GPLWILGDVFIGRYYTVFDRDNNRVGFAEA 409
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 218 bits (532), Expect = 2e-56
Identities = 101/210 (48%), Positives = 136/210 (64%), Gaps = 2/210 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
GMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G L
Sbjct: 200 GMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSL 259
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
+ + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 260 SYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVP 319
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P P
Sbjct: 320 LIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPS 379
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
GPLWILGDVFIG+YYT FD N ++GFA A
Sbjct: 380 GPLWILGDVFIGRYYTVFDRDNNRVGFAEA 409
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 218 bits (532), Expect = 2e-56
Identities = 101/210 (48%), Positives = 136/210 (64%), Gaps = 2/210 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
GMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G L
Sbjct: 200 GMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSL 259
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
+ + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 260 SYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVP 319
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P P
Sbjct: 320 LIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPS 379
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
GPLWILGDVFIG+YYT FD N ++GFA A
Sbjct: 380 GPLWILGDVFIGRYYTVFDRDNNRVGFAEA 409
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 218 bits (532), Expect = 2e-56
Identities = 101/210 (48%), Positives = 136/210 (64%), Gaps = 2/210 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
GMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G L
Sbjct: 200 GMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSL 259
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
+ + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 260 SYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVP 319
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P P
Sbjct: 320 LIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPS 379
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
GPLWILGDVFIG+YYT FD N ++GFA A
Sbjct: 380 GPLWILGDVFIGRYYTVFDRDNNRVGFAEA 409
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 218 bits (532), Expect = 2e-56
Identities = 101/210 (48%), Positives = 136/210 (64%), Gaps = 2/210 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
GMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G L
Sbjct: 200 GMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSL 259
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
+ + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 260 SYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVP 319
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P P
Sbjct: 320 LIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPS 379
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
GPLWILGDVFIG+YYT FD N ++GFA A
Sbjct: 380 GPLWILGDVFIGRYYTVFDRDNNRVGFAEA 409
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 218 bits (532), Expect = 2e-56
Identities = 101/210 (48%), Positives = 136/210 (64%), Gaps = 2/210 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
GMA+ I+V++V PVFDN++ Q LV Q +FSFYL+RDP A G+D +Y+G L
Sbjct: 200 GMAYPRISVNNVLPVFDNLMQQKLVDQNIFSFYLSRDPDAQPGGELMLGGTDSKYYKGSL 259
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
+ + R YW+ H+D V V + C +GC AI DTGTSL+ GP EV L A+GA
Sbjct: 260 SYLNVTRKAYWQVHLDQVEVASGLTLCKEGCEAIVDTGTSLMVGPVDEVRELQKAIGAVP 319
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ C + LP +T + G + L DY L+V+Q G T+CLSGFM +D+P P
Sbjct: 320 LIQGEYMIPCEKVSTLPAITLKLGGKGYKLSPEDYTLKVSQAGKTLCLSGFMGMDIPPPS 379
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
GPLWILGDVFIG+YYT FD N ++GFA A
Sbjct: 380 GPLWILGDVFIGRYYTVFDRDNNRVGFAEA 409
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 207 bits (505), Expect = 3e-53
Identities = 100/202 (49%), Positives = 130/202 (64%), Gaps = 2/202 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP GSDPAHY L
Sbjct: 188 GLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIPPL 247
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ YW+ HM+ V V CA+GC+AI DTGTSLI GP++E+ AL+AA+G
Sbjct: 248 TFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIP 307
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ CS IP LP V+F + G F L +DYV++ + G +CLSGF ALDVP P
Sbjct: 308 LLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPA 367
Query: 109 GPLWILGDVFIGKYYTEFDAGN 44
GP WILGDVF+G Y FD G+
Sbjct: 368 GPFWILGDVFLGTYVAVFDRGD 389
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 207 bits (505), Expect = 3e-53
Identities = 100/202 (49%), Positives = 130/202 (64%), Gaps = 2/202 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP GSDPAHY L
Sbjct: 188 GLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIPPL 247
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ YW+ HM+ V V CA+GC+AI DTGTSLI GP++E+ AL+AA+G
Sbjct: 248 TFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIP 307
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ CS IP LP V+F + G F L +DYV++ + G +CLSGF ALDVP P
Sbjct: 308 LLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPA 367
Query: 109 GPLWILGDVFIGKYYTEFDAGN 44
GP WILGDVF+G Y FD G+
Sbjct: 368 GPFWILGDVFLGTYVAVFDRGD 389
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 207 bits (505), Expect = 3e-53
Identities = 100/202 (49%), Positives = 130/202 (64%), Gaps = 2/202 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP GSDPAHY L
Sbjct: 188 GLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIPPL 247
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ YW+ HM+ V V CA+GC+AI DTGTSLI GP++E+ AL+AA+G
Sbjct: 248 TFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIP 307
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ CS IP LP V+F + G F L +DYV++ + G +CLSGF ALDVP P
Sbjct: 308 LLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPA 367
Query: 109 GPLWILGDVFIGKYYTEFDAGN 44
GP WILGDVF+G Y FD G+
Sbjct: 368 GPFWILGDVFLGTYVAVFDRGD 389
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 207 bits (505), Expect = 3e-53
Identities = 100/202 (49%), Positives = 130/202 (64%), Gaps = 2/202 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ F ++V+ V P D +V QGL+ +PVFSFYLNRDP GSDPAHY L
Sbjct: 188 GLGFPILSVEGVRPPMDVLVEQGLLDKPVFSFYLNRDPEEPDGGELVLGGSDPAHYIPPL 247
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ YW+ HM+ V V CA+GC+AI DTGTSLI GP++E+ AL+AA+G
Sbjct: 248 TFVPVTVPAYWQIHMERVKVGPGLTLCAKGCAAILDTGTSLITGPTEEIRALHAAIGGIP 307
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ CS IP LP V+F + G F L +DYV++ + G +CLSGF ALDVP P
Sbjct: 308 LLAGEYIILCSEIPKLPAVSFLLGGVWFNLTAHDYVIQTTRNGVRLCLSGFQALDVPPPA 367
Query: 109 GPLWILGDVFIGKYYTEFDAGN 44
GP WILGDVF+G Y FD G+
Sbjct: 368 GPFWILGDVFLGTYVAVFDRGD 389
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 200 bits (488), Expect = 3e-51
Identities = 98/206 (47%), Positives = 129/206 (62%), Gaps = 2/206 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ F ++V+ V P D +V QGL+ +PVFSFY NRDP GSDPAHY L
Sbjct: 184 GLGFPILSVEGVRPPLDVLVEQGLLDKPVFSFYFNRDPEVADGGELVLGGSDPAHYIPPL 243
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ YW+ HM+ V V + CAQGC+AI DTGT +I GP++E+ AL+AA+G
Sbjct: 244 TFVPVTVPAYWQIHMERVKVGSRLTLCAQGCAAILDTGTPVIVGPTEEIRALHAAIGGIP 303
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ CS IP LP V+ I G F L DYV++ AQ +CLSGF ALD+ P
Sbjct: 304 LLAGEYIIRCSEIPKLPAVSLLIGGVWFNLTAQDYVIQFAQGDVRLCLSGFRALDIASPP 363
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLG 32
P+WILGDVF+G Y T FD G+ + G
Sbjct: 364 VPVWILGDVFLGAYVTVFDRGDMKSG 389
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 200 bits (488), Expect = 3e-51
Identities = 98/206 (47%), Positives = 129/206 (62%), Gaps = 2/206 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ F ++V+ V P D +V QGL+ +PVFSFY NRDP GSDPAHY L
Sbjct: 188 GLGFPILSVEGVRPPLDVLVEQGLLDKPVFSFYFNRDPEVADGGELVLGGSDPAHYIPPL 247
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ YW+ HM+ V V + CAQGC+AI DTGT +I GP++E+ AL+AA+G
Sbjct: 248 TFVPVTVPAYWQIHMERVKVGSRLTLCAQGCAAILDTGTPVIVGPTEEIRALHAAIGGIP 307
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y++ CS IP LP V+ I G F L DYV++ AQ +CLSGF ALD+ P
Sbjct: 308 LLAGEYIIRCSEIPKLPAVSLLIGGVWFNLTAQDYVIQFAQGDVRLCLSGFRALDIASPP 367
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLG 32
P+WILGDVF+G Y T FD G+ + G
Sbjct: 368 VPVWILGDVFLGAYVTVFDRGDMKSG 393
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 193 bits (470), Expect = 5e-49
Identities = 95/211 (45%), Positives = 132/211 (62%), Gaps = 2/211 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ + YW+ +D++ V + FC++GC AI DTGTSLI GPS +++ L A+GA
Sbjct: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y V+C+ + +P VTFTI G +TL Y L G C SGF LD+ P
Sbjct: 306 VD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPAV 17
GPLWILGDVFI ++Y+ FD GN ++G APAV
Sbjct: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 193 bits (470), Expect = 5e-49
Identities = 95/211 (45%), Positives = 132/211 (62%), Gaps = 2/211 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ + YW+ +D++ V + FC++GC AI DTGTSLI GPS +++ L A+GA
Sbjct: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y V+C+ + +P VTFTI G +TL Y L G C SGF LD+ P
Sbjct: 306 VD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPAV 17
GPLWILGDVFI ++Y+ FD GN ++G APAV
Sbjct: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 193 bits (470), Expect = 5e-49
Identities = 95/211 (45%), Positives = 132/211 (62%), Gaps = 2/211 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ + YW+ +D++ V + FC++GC AI DTGTSLI GPS +++ L A+GA
Sbjct: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y V+C+ + +P VTFTI G +TL Y L G C SGF LD+ P
Sbjct: 306 VD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPAV 17
GPLWILGDVFI ++Y+ FD GN ++G APAV
Sbjct: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 193 bits (470), Expect = 5e-49
Identities = 95/211 (45%), Positives = 132/211 (62%), Gaps = 2/211 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ + YW+ +D++ V + FC++GC AI DTGTSLI GPS +++ L A+GA
Sbjct: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y V+C+ + +P VTFTI G +TL Y L G C SGF LD+ P
Sbjct: 306 VD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPAV 17
GPLWILGDVFI ++Y+ FD GN ++G APAV
Sbjct: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 193 bits (470), Expect = 5e-49
Identities = 95/211 (45%), Positives = 132/211 (62%), Gaps = 2/211 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
Query: 466 VRVPLLRDTYWEFHMDSVNVNAS-RFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ + YW+ +D++ V + FC++GC AI DTGTSLI GPS +++ L A+GA
Sbjct: 246 NWVPVTKQAYWQIALDNIQVGGTVMFCSEGCQAIVDTGTSLITGPSDKIKQLQNAIGAAP 305
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G+Y V+C+ + +P VTFTI G +TL Y L G C SGF LD+ P
Sbjct: 306 VD-GEYAVECANLNVMPDVTFTINGVPYTLSPTAYTLLDFVDGMQFCSSGFQGLDIHPPA 364
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPAV 17
GPLWILGDVFI ++Y+ FD GN ++G APAV
Sbjct: 365 GPLWILGDVFIRQFYSVFDRGNNRVGLAPAV 395
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 169 bits (410), Expect = 1e-41
Identities = 84/212 (39%), Positives = 120/212 (56%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRG 473
GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY G
Sbjct: 88 GMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEG 147
Query: 472 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 296
+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 148 NFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGA 207
Query: 295 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 116
YVV C+ P LP ++F + G ++TL DY+ + + +C A+D+P
Sbjct: 208 KEKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYIFQESYSSKKLCTLAIHAMDIPP 267
Query: 115 PMGPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
P GP W LG FI K+YTEFD N ++GFA A
Sbjct: 268 PTGPTWALGATFIRKFYTEFDRRNNRIGFALA 299
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (409), Expect = 1e-41
Identities = 86/212 (40%), Positives = 121/212 (57%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRG 473
GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY G
Sbjct: 195 GMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEG 254
Query: 472 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 296
+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 255 NFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGA 314
Query: 295 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 116
F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+P
Sbjct: 315 KKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPP 373
Query: 115 PMGPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
P GP W LG FI K+YTEFD N ++GFA A
Sbjct: 374 PTGPTWALGATFIRKFYTEFDRRNNRIGFALA 405
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (409), Expect = 1e-41
Identities = 86/212 (40%), Positives = 121/212 (57%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRG 473
GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY G
Sbjct: 195 GMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEG 254
Query: 472 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 296
+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 255 NFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGA 314
Query: 295 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 116
F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+P
Sbjct: 315 KKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPP 373
Query: 115 PMGPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
P GP W LG FI K+YTEFD N ++GFA A
Sbjct: 374 PTGPTWALGATFIRKFYTEFDRRNNRIGFALA 405
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 168 bits (409), Expect = 1e-41
Identities = 86/212 (40%), Positives = 121/212 (57%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRG 473
GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY G
Sbjct: 195 GMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEG 254
Query: 472 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 296
+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 255 NFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGA 314
Query: 295 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 116
F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+P
Sbjct: 315 KKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPP 373
Query: 115 PMGPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
P GP W LG FI K+YTEFD N ++GFA A
Sbjct: 374 PTGPTWALGATFIRKFYTEFDRRNNRIGFALA 405
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (409), Expect = 1e-41
Identities = 86/212 (40%), Positives = 121/212 (57%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRG 473
GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY G
Sbjct: 195 GMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEG 254
Query: 472 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 296
+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 255 NFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGA 314
Query: 295 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 116
F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+P
Sbjct: 315 KKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPP 373
Query: 115 PMGPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
P GP W LG FI K+YTEFD N ++GFA A
Sbjct: 374 PTGPTWALGATFIRKFYTEFDRRNNRIGFALA 405
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (409), Expect = 1e-41
Identities = 86/212 (40%), Positives = 121/212 (57%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRG 473
GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY G
Sbjct: 195 GMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEG 254
Query: 472 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 296
+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 255 NFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGA 314
Query: 295 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 116
F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+P
Sbjct: 315 KKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPP 373
Query: 115 PMGPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
P GP W LG FI K+YTEFD N ++GFA A
Sbjct: 374 PTGPTWALGATFIRKFYTEFDRRNNRIGFALA 405
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (409), Expect = 1e-41
Identities = 86/212 (40%), Positives = 121/212 (57%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRG 473
GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY G
Sbjct: 195 GMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEG 254
Query: 472 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 296
+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 255 NFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGA 314
Query: 295 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 116
F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+P
Sbjct: 315 KKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPP 373
Query: 115 PMGPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
P GP W LG FI K+YTEFD N ++GFA A
Sbjct: 374 PTGPTWALGATFIRKFYTEFDRRNNRIGFALA 405
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 168 bits (409), Expect = 1e-41
Identities = 86/212 (40%), Positives = 121/212 (57%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDP--GATTXXXXXXXGSDPAHYRG 473
GM F A+ VTP+FDN+++QG++ + VFSFY NRD + GSDP HY G
Sbjct: 195 GMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGGQIVLGGSDPQHYEG 254
Query: 472 DLVRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGA 296
+ + L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 255 NFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGA 314
Query: 295 TAIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPK 116
F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+P
Sbjct: 315 KKRLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPP 373
Query: 115 PMGPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
P GP W LG FI K+YTEFD N ++GFA A
Sbjct: 374 PTGPTWALGATFIRKFYTEFDRRNNRIGFALA 405
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 167 bits (407), Expect = 2e-41
Identities = 85/210 (40%), Positives = 121/210 (57%), Gaps = 2/210 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
GM F A+ VTP+FDN+++QG++ + VFSFY NR+ + GSDP HY G+
Sbjct: 195 GMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRN-SQSLGGQIVLGGSDPQHYEGNF 253
Query: 466 VRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
+ L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 254 HYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKK 313
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+P P
Sbjct: 314 RLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPT 372
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
GP W LG FI K+YTEFD N ++GFA A
Sbjct: 373 GPTWALGATFIRKFYTEFDRRNNRIGFALA 402
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 166 bits (403), Expect = 7e-41
Identities = 85/210 (40%), Positives = 121/210 (57%), Gaps = 2/210 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
GM F A+ VTP+FDN+++QG++ + VFSFY NR+ + GSDP HY G+
Sbjct: 195 GMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRN-SQSLGGQIVLGGSDPQHYEGNF 253
Query: 466 VRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
+ L++ W+ M V+V +S C GC A+ DTG S I+G + +E L A+GA
Sbjct: 254 HYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSCIEKLMEALGAKK 313
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
F YVV C+ P LP ++F + G ++TL DYV + + +C A+D+P P
Sbjct: 314 RLF-DYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPT 372
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
GP W LG FI K+YTEFD N ++GFA A
Sbjct: 373 GPTWALGATFIRKFYTEFDRRNNRIGFALA 402
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 164 bits (399), Expect = 2e-40
Identities = 85/209 (40%), Positives = 123/209 (58%), Gaps = 2/209 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+A+ +I+ TPVFDN+ QGLV Q +FS YL+ D + + D ++Y G L
Sbjct: 184 GLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDKSGSVVIFGGI--DSSYYTGSL 241
Query: 466 VRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ + YW+ +DS+ +N CA+GC AI DTGTSL+ GP+ + + + +GA+
Sbjct: 242 NWVPVTVEGYWQITVDSITMNGETIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASE 301
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G VV CS I LP + FTI G + + + Y+L+ C+SGF ++VP
Sbjct: 302 NSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNVPTES 357
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAP 23
G LWILGDVFI +Y+T FD N Q+G AP
Sbjct: 358 GELWILGDVFIRQYFTVFDRANNQVGLAP 386
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 163 bits (396), Expect = 5e-40
Identities = 84/209 (40%), Positives = 123/209 (58%), Gaps = 2/209 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+A+ +I+ TPVFDN+ QGLV Q +FS YL+ D + + D ++Y G L
Sbjct: 184 GLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGI--DSSYYTGSL 241
Query: 466 VRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ + YW+ +DS+ +N CA+GC AI DTGTSL+ GP+ + + + +GA+
Sbjct: 242 NWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASE 301
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G VV CS I LP + FTI G + + + Y+L+ C+SGF +++P
Sbjct: 302 NSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNLPTES 357
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAP 23
G LWILGDVFI +Y+T FD N Q+G AP
Sbjct: 358 GELWILGDVFIRQYFTVFDRANNQVGLAP 386
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 161 bits (392), Expect = 1e-39
Identities = 83/209 (39%), Positives = 123/209 (58%), Gaps = 2/209 (0%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLV-QPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+A+ +I+ TPVFDN+ QGLV Q +FS YL+ D + + D ++Y G L
Sbjct: 184 GLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGI--DSSYYTGSL 241
Query: 466 VRVPLLRDTYWEFHMDSVNVNASRF-CAQGCSAIADTGTSLIAGPSKEVEALNAAVGATA 290
VP+ + YW+ +DS+ +N CA+GC AI DTGTSL+ GP+ + + + +GA+
Sbjct: 242 NWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASE 301
Query: 289 IAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKPM 110
+ G VV CS I LP + FTI G + + + Y+L+ C+SGF +++P
Sbjct: 302 NSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQ----SEGSCISGFQGMNLPTES 357
Query: 109 GPLWILGDVFIGKYYTEFDAGNRQLGFAP 23
G LWILGDVFI +Y+T F+ N Q+G AP
Sbjct: 358 GELWILGDVFIRQYFTVFERANNQVGLAP 386
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 142 bits (344), Expect = 1e-33
Identities = 77/212 (36%), Positives = 117/212 (55%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G +
Sbjct: 181 GLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQI 239
Query: 466 VRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGAT 293
P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A GA
Sbjct: 240 YWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQ 299
Query: 292 AIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKP 113
+GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 300 EDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQ 355
Query: 112 MG-PLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
G PLWILGDVF+ YY+ +D GN ++GFA A
Sbjct: 356 NGQPLWILGDVFLRSYYSVYDLGNNRVGFATA 387
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 142 bits (344), Expect = 1e-33
Identities = 77/212 (36%), Positives = 117/212 (55%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G +
Sbjct: 181 GLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQI 239
Query: 466 VRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGAT 293
P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A GA
Sbjct: 240 YWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQ 299
Query: 292 AIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKP 113
+GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 300 EDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQ 355
Query: 112 MG-PLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
G PLWILGDVF+ YY+ +D GN ++GFA A
Sbjct: 356 NGQPLWILGDVFLRSYYSVYDLGNNRVGFATA 387
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 142 bits (344), Expect = 1e-33
Identities = 77/212 (36%), Positives = 117/212 (55%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G +
Sbjct: 178 GLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQI 236
Query: 466 VRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGAT 293
P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A GA
Sbjct: 237 YWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQ 296
Query: 292 AIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKP 113
+GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 297 EDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQ 352
Query: 112 MG-PLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
G PLWILGDVF+ YY+ +D GN ++GFA A
Sbjct: 353 NGQPLWILGDVFLRSYYSVYDLGNNRVGFATA 384
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 142 bits (344), Expect = 1e-33
Identities = 77/212 (36%), Positives = 117/212 (55%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G +
Sbjct: 181 GLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQI 239
Query: 466 VRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGAT 293
P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A GA
Sbjct: 240 YWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQ 299
Query: 292 AIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKP 113
+GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 300 EDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQ 355
Query: 112 MG-PLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
G PLWILGDVF+ YY+ +D GN ++GFA A
Sbjct: 356 NGQPLWILGDVFLRSYYSVYDLGNNRVGFATA 387
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 142 bits (344), Expect = 1e-33
Identities = 77/212 (36%), Positives = 117/212 (55%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G +
Sbjct: 181 GLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQI 239
Query: 466 VRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGAT 293
P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A GA
Sbjct: 240 YWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQ 299
Query: 292 AIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKP 113
+GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 300 EDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQ 355
Query: 112 MG-PLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
G PLWILGDVF+ YY+ +D GN ++GFA A
Sbjct: 356 NGQPLWILGDVFLRSYYSVYDLGNNRVGFATA 387
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 142 bits (344), Expect = 1e-33
Identities = 77/212 (36%), Positives = 117/212 (55%), Gaps = 4/212 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+A+ ++VD T MV +G L PVFS YL+ G++ D + Y G +
Sbjct: 181 GLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQGSSGGAVVFGGV-DSSLYTGQI 239
Query: 466 VRVPLLRDTYWEFHMDS--VNVNASRFCAQGCSAIADTGTSLIAGPSKEVEALNAAVGAT 293
P+ ++ YW+ ++ + AS +C++GC AI DTGTSL+ P + + AL A GA
Sbjct: 240 YWAPVTQELYWQIGIEEFLIGGQASGWCSEGCQAIVDTGTSLLTVPQQYMSALLQATGAQ 299
Query: 292 AIAFGQYVVDCSLIPHLPRVTFTIAGNDFTLEGNDYVLRVAQFGHTVCLSGFMALDVPKP 113
+GQ++V+C+ I +LP +TF I G +F L + Y+L + C G +
Sbjct: 300 EDEYGQFLVNCNSIQNLPSLTFIINGVEFPLPPSSYILS----NNGYCTVGVEPTYLSSQ 355
Query: 112 MG-PLWILGDVFIGKYYTEFDAGNRQLGFAPA 20
G PLWILGDVF+ YY+ +D GN ++GFA A
Sbjct: 356 NGQPLWILGDVFLRSYYSVYDLGNNRVGFATA 387
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 63.7 bits (148), Expect = 5e-10
Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 1/78 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
Query: 466 VRVPLLRDTYWEFHMDSV 413
VP+ + YW+ +D++
Sbjct: 246 NWVPVTKQAYWQIALDNM 263
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 63.7 bits (148), Expect = 5e-10
Identities = 30/78 (38%), Positives = 47/78 (60%), Gaps = 1/78 (1%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQGLVQ-PVFSFYLNRDPGATTXXXXXXXGSDPAHYRGDL 467
G+ + ++AV VTPVFDNM+AQ LV P+FS Y++ +P G D +H+ G L
Sbjct: 186 GLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSL 245
Query: 466 VRVPLLRDTYWEFHMDSV 413
VP+ + YW+ +D++
Sbjct: 246 NWVPVTKQAYWQIALDNM 263
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 41.5 bits (93), Expect = 0.002
Identities = 36/144 (25%), Positives = 67/144 (46%), Gaps = 14/144 (9%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 198 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 257
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 258 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 315
Query: 325 VEALNAAVGATAIAFGQYVVDCSL 254
+A+ AV ++ + Q ++ L
Sbjct: 316 FDAVVEAVARASLLYIQPMMGAGL 339
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 40.7 bits (91), Expect = 0.004
Identities = 35/134 (26%), Positives = 64/134 (47%), Gaps = 15/134 (11%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFYLNRDPG------ATTXXXXXXXGSDP 488
G+A++T+A + FD++V Q + VFS + R G T G +P
Sbjct: 103 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQM-RGAGLPVAGSGTNGGSLVLGGIEP 161
Query: 487 AHYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSK 329
+ Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 162 SLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQK 219
Query: 328 EVEALNAAVGATAI 287
+A+ AV ++
Sbjct: 220 VFDAVVEAVARASL 233
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 39.5 bits (88), Expect = 0.010
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 198 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 257
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 258 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 315
Query: 325 VEALNAAVGATAI 287
+A+ AV ++
Sbjct: 316 FDAVVEAVARASL 328
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 39.5 bits (88), Expect = 0.010
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 198 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 257
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 258 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 315
Query: 325 VEALNAAVGATAI 287
+A+ AV ++
Sbjct: 316 FDAVVEAVARASL 328
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 39.5 bits (88), Expect = 0.010
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 95 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 154
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 155 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 212
Query: 325 VEALNAAVGATAI 287
+A+ AV ++
Sbjct: 213 FDAVVEAVARASL 225
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 39.5 bits (88), Expect = 0.010
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 119 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 178
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 179 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 236
Query: 325 VEALNAAVGATAI 287
+A+ AV ++
Sbjct: 237 FDAVVEAVARASL 249
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 39.5 bits (88), Expect = 0.010
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 198 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 257
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 258 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 315
Query: 325 VEALNAAVGATAI 287
+A+ AV ++
Sbjct: 316 FDAVVEAVARASL 328
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 39.5 bits (88), Expect = 0.010
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 198 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 257
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 258 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 315
Query: 325 VEALNAAVGATAI 287
+A+ AV ++
Sbjct: 316 FDAVVEAVARASL 328
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 39.5 bits (88), Expect = 0.010
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 198 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 257
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 258 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 315
Query: 325 VEALNAAVGATAI 287
+A+ AV ++
Sbjct: 316 FDAVVEAVARASL 328
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 39.5 bits (88), Expect = 0.010
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 198 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 257
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 258 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 315
Query: 325 VEALNAAVGATAI 287
+A+ AV ++
Sbjct: 316 FDAVVEAVARASL 328
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 39.5 bits (88), Expect = 0.010
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 198 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 257
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 258 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 315
Query: 325 VEALNAAVGATAI 287
+A+ AV ++
Sbjct: 316 FDAVVEAVARASL 328
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 39.5 bits (88), Expect = 0.010
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 198 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 257
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 258 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 315
Query: 325 VEALNAAVGATAI 287
+A+ AV ++
Sbjct: 316 FDAVVEAVARASL 328
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 39.5 bits (88), Expect = 0.010
Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFSFY-----LNRDPGATTXXXXXXXGSDPA 485
G+A++T+A + FD++V Q + VFS L T G +P+
Sbjct: 198 GLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPS 257
Query: 484 HYRGDLVRVPLLRDTYWEFHM-------DSVNVNASRFCAQGCSAIADTGTSLIAGPSKE 326
Y+GD+ P+ + Y++ + S+N++ + A AI D+GT+L+ P K
Sbjct: 258 LYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNAD--KAIVDSGTTLLRLPQKV 315
Query: 325 VEALNAAVGATAI 287
+A+ AV ++
Sbjct: 316 FDAVVEAVARASL 328
>AL365205-2|CAI95135.1| 140|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 140
Score = 35.1 bits (77), Expect = 0.22
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Frame = -2
Query: 643 GMAFSTIAVDHVTPVFDNMVAQG-LVQPVFSFYLNRDPG 530
G+A+ ++VD T MV +G L PVFS YL+ G
Sbjct: 102 GLAYPALSVDEATTAMQGMVQEGALTSPVFSVYLSNQQG 140
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.28
Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGS 494
G+A++ IA D + P FD++V Q V +FS F LN+ A+ G
Sbjct: 181 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 240
Query: 493 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSK 329
D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P K
Sbjct: 241 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 300
Query: 328 EVEALNAAVGATA 290
EA ++ A +
Sbjct: 301 VFEAAVKSIKAAS 313
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.28
Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGS 494
G+A++ IA D + P FD++V Q V +FS F LN+ A+ G
Sbjct: 181 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 240
Query: 493 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSK 329
D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P K
Sbjct: 241 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 300
Query: 328 EVEALNAAVGATA 290
EA ++ A +
Sbjct: 301 VFEAAVKSIKAAS 313
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.28
Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGS 494
G+A++ IA D + P FD++V Q V +FS F LN+ A+ G
Sbjct: 181 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 240
Query: 493 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSK 329
D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P K
Sbjct: 241 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 300
Query: 328 EVEALNAAVGATA 290
EA ++ A +
Sbjct: 301 VFEAAVKSIKAAS 313
>BC015008-1|AAH15008.1| 203|Homo sapiens HAGHL protein protein.
Length = 203
Score = 34.7 bits (76), Expect = 0.28
Identities = 47/132 (35%), Positives = 56/132 (42%), Gaps = 11/132 (8%)
Frame = +2
Query: 17 HGGREPELAVPRVELRVVLADEHVPQDPQR-AHG--LRHVQRHEAGQAHRVPELCHPEHV 187
H PELA R L V+ ADE + +R AHG LR R G+ R P P
Sbjct: 59 HARGNPELARLRPGLAVLGADERIFSLTRRLAHGEELRVSARSREGRGGR-PGSTRPHR- 116
Query: 188 VVALEREVVPGDGKGDSRQVRYEAAVHDVLPEGDGR--GAHRRVEGFHLLGG-----PGD 346
A V G + R H++LP G GR G R V G +GG PG
Sbjct: 117 -SACSSAAVRGHPRALPPDARPHRRPHELLPVG-GRLPGPTRPVLGRRAVGGRLRLVPGG 174
Query: 347 QRRARVGD-GRA 379
QR A V + GRA
Sbjct: 175 QRPADVPEPGRA 186
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.28
Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGS 494
G+A++ IA D + P FD++V Q V +FS F LN+ A+ G
Sbjct: 181 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 240
Query: 493 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSK 329
D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P K
Sbjct: 241 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 300
Query: 328 EVEALNAAVGATA 290
EA ++ A +
Sbjct: 301 VFEAAVKSIKAAS 313
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.28
Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGS 494
G+A++ IA D + P FD++V Q V +FS F LN+ A+ G
Sbjct: 181 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 240
Query: 493 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSK 329
D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P K
Sbjct: 241 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 300
Query: 328 EVEALNAAVGATA 290
EA ++ A +
Sbjct: 301 VFEAAVKSIKAAS 313
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.28
Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGS 494
G+A++ IA D + P FD++V Q V +FS F LN+ A+ G
Sbjct: 181 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 240
Query: 493 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSK 329
D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P K
Sbjct: 241 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 300
Query: 328 EVEALNAAVGATA 290
EA ++ A +
Sbjct: 301 VFEAAVKSIKAAS 313
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 34.7 bits (76), Expect = 0.28
Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGS 494
G+A++ IA D + P FD++V Q V +FS F LN+ A+ G
Sbjct: 168 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 227
Query: 493 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSK 329
D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P K
Sbjct: 228 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 287
Query: 328 EVEALNAAVGATA 290
EA ++ A +
Sbjct: 288 VFEAAVKSIKAAS 300
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.28
Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGS 494
G+A++ IA D + P FD++V Q V +FS F LN+ A+ G
Sbjct: 181 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 240
Query: 493 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSK 329
D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P K
Sbjct: 241 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 300
Query: 328 EVEALNAAVGATA 290
EA ++ A +
Sbjct: 301 VFEAAVKSIKAAS 313
>AB177847-1|BAD66825.1| 396|Homo sapiens KIAA1149 splice variant 1
protein.
Length = 396
Score = 34.7 bits (76), Expect = 0.28
Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGS 494
G+A++ IA D + P FD++V Q V +FS F LN+ A+ G
Sbjct: 76 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 135
Query: 493 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSK 329
D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P K
Sbjct: 136 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 195
Query: 328 EVEALNAAVGATA 290
EA ++ A +
Sbjct: 196 VFEAAVKSIKAAS 208
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 34.7 bits (76), Expect = 0.28
Identities = 38/133 (28%), Positives = 61/133 (45%), Gaps = 15/133 (11%)
Frame = -2
Query: 643 GMAFSTIAV--DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGS 494
G+A++ IA D + P FD++V Q V +FS F LN+ A+ G
Sbjct: 212 GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI 271
Query: 493 DPAHYRGDLVRVPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSK 329
D + Y G L P+ R+ Y+E + V +N C + +I D+GT+ + P K
Sbjct: 272 DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK 331
Query: 328 EVEALNAAVGATA 290
EA ++ A +
Sbjct: 332 VFEAAVKSIKAAS 344
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 31.9 bits (69), Expect = 2.0
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 13/122 (10%)
Frame = -2
Query: 616 DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGSDPAHYRGDLVR 461
D + P FD++V Q V +FS F LN+ A+ G D + Y G L
Sbjct: 148 DSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWY 207
Query: 460 VPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSKEVEALNAAVGA 296
P+ R+ Y+E + V +N C + +I D+GT+ + P K EA ++ A
Sbjct: 208 TPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKA 267
Query: 295 TA 290
+
Sbjct: 268 AS 269
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 31.9 bits (69), Expect = 2.0
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 13/122 (10%)
Frame = -2
Query: 616 DHVTPVFDNMVAQGLVQPVFS-------FYLNRDPG-ATTXXXXXXXGSDPAHYRGDLVR 461
D + P FD++V Q V +FS F LN+ A+ G D + Y G L
Sbjct: 148 DSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWY 207
Query: 460 VPLLRDTYWEFHMDSVNVNASRF---CAQ--GCSAIADTGTSLIAGPSKEVEALNAAVGA 296
P+ R+ Y+E + V +N C + +I D+GT+ + P K EA ++ A
Sbjct: 208 TPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKA 267
Query: 295 TA 290
+
Sbjct: 268 AS 269
>AK125511-1|BAC86188.1| 559|Homo sapiens rome) (ELN). protein.
Length = 559
Score = 31.5 bits (68), Expect = 2.7
Identities = 13/31 (41%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
Frame = -3
Query: 174 WHNSGTRCACPA-SW--RWTCRSPWARCGSW 91
W G+ C C + SW W+ R W+ CGSW
Sbjct: 457 WSWRGSWCRCGSWSWLGSWSWRGSWSWCGSW 487
>U94332-1|AAB53709.1| 401|Homo sapiens osteoprotegerin protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.5
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +3
Query: 69 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 170
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>BC030155-1|AAH30155.1| 401|Homo sapiens tumor necrosis factor
receptor superfamily, member 11b (osteoprotegerin)
protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.5
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +3
Query: 69 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 170
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>AY466112-1|AAR23265.1| 401|Homo sapiens tumor necrosis factor
receptor superfamily, member 11b (osteoprotegerin)
protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.5
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +3
Query: 69 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 170
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>AK223155-1|BAD96875.1| 401|Homo sapiens osteoprotegerin precursor
variant protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.5
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +3
Query: 69 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 170
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>AF134187-1|AAF20168.1| 372|Homo sapiens osteoprotegerin protein.
Length = 372
Score = 31.1 bits (67), Expect = 3.5
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +3
Query: 69 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 170
YL + + S P GFG A P+R+TVC C
Sbjct: 91 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 124
>AB008822-1|BAA32076.1| 401|Homo sapiens osteoclastogenesis
inhibitory factor protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.5
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +3
Query: 69 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 170
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>AB002146-1|BAA25910.1| 401|Homo sapiens osteoclastogenesis
inhibitory factor (OCIF) protein.
Length = 401
Score = 31.1 bits (67), Expect = 3.5
Identities = 14/34 (41%), Positives = 18/34 (52%)
Frame = +3
Query: 69 YLPMNTSPRIHSGPMGFGTSSAMKPDRHTVCPNC 170
YL + + S P GFG A P+R+TVC C
Sbjct: 112 YLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRC 145
>Z97652-2|CAM26431.1| 1269|Homo sapiens Crm, cramped-like
(Drosophila) protein.
Length = 1269
Score = 29.9 bits (64), Expect = 8.1
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +3
Query: 276 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 437
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 628 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 681
>U52840-1|AAC09473.1| 1074|Homo sapiens semaphorin F homolog
protein.
Length = 1074
Score = 29.9 bits (64), Expect = 8.1
Identities = 10/22 (45%), Positives = 13/22 (59%)
Frame = -3
Query: 147 CPASWRWTCRSPWARCGSWGTC 82
CP W+C SPW +C + TC
Sbjct: 838 CPVDGVWSCWSPWTKCSA--TC 857
>BC146661-1|AAI46662.1| 686|Homo sapiens STIM2 protein protein.
Length = 686
Score = 29.9 bits (64), Expect = 8.1
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 2/55 (3%)
Frame = -1
Query: 248 APAASHLYHRRERLHARGQRLRAP--GGTIRAHGVPVRLHGAGRAEAHGPAVDPG 90
AP S RR R + AP G ++A G P+R H A H PA PG
Sbjct: 20 APGGSPCLRRRGRPEESPAAVVAPRGAGELQAAGAPLRFHPASPRRLH-PASTPG 73
>BC115696-1|AAI15697.1| 1074|Homo sapiens sema domain, seven
thrombospondin repeats (type 1 and type 1-like),
transmembra protein.
Length = 1074
Score = 29.9 bits (64), Expect = 8.1
Identities = 10/22 (45%), Positives = 13/22 (59%)
Frame = -3
Query: 147 CPASWRWTCRSPWARCGSWGTC 82
CP W+C SPW +C + TC
Sbjct: 838 CPVDGVWSCWSPWTKCSA--TC 857
>AL031708-1|CAM26357.1| 1269|Homo sapiens Crm, cramped-like
(Drosophila) protein.
Length = 1269
Score = 29.9 bits (64), Expect = 8.1
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +3
Query: 276 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 437
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 628 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 681
>AL031009-1|CAM26477.1| 1269|Homo sapiens Crm, cramped-like
(Drosophila) protein.
Length = 1269
Score = 29.9 bits (64), Expect = 8.1
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +3
Query: 276 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 437
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 628 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 681
>AE006639-2|AAK61288.1| 1587|Homo sapiens unknown protein.
Length = 1587
Score = 29.9 bits (64), Expect = 8.1
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +3
Query: 276 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 437
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 880 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 933
>AB040915-1|BAA96006.1| 818|Homo sapiens KIAA1482 protein protein.
Length = 818
Score = 29.9 bits (64), Expect = 8.1
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 2/55 (3%)
Frame = -1
Query: 248 APAASHLYHRRERLHARGQRLRAP--GGTIRAHGVPVRLHGAGRAEAHGPAVDPG 90
AP S RR R + AP G ++A G P+R H A H PA PG
Sbjct: 5 APGGSPCLRRRGRPEESPAAVVAPRGAGELQAAGAPLRFHPASPRRLH-PASTPG 58
>AB037847-1|BAA92664.2| 1066|Homo sapiens KIAA1426 protein protein.
Length = 1066
Score = 29.9 bits (64), Expect = 8.1
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +3
Query: 276 CPKAMAVAPTAALRASTSLEGPAISDVPVSAMAEQPWAQKRLALTLTESMWNSQ 437
C K +A AP L+ S GP S +A + RLA L E WN Q
Sbjct: 425 CTKDLADAPAEELQEKGSPAGPPPSQGQPAARPPKEVPASRLAQQLREEGWNLQ 478
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,357,532
Number of Sequences: 237096
Number of extensions: 2192202
Number of successful extensions: 8687
Number of sequences better than 10.0: 83
Number of HSP's better than 10.0 without gapping: 7878
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8576
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7141427170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -