Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmmt12o18
(629 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J03620-1|AAA35764.1| 509|Homo sapiens protein ( Human dihydroli... 185 1e-46
J03490-1|AAA59527.1| 509|Homo sapiens ZP3 protein. 185 1e-46
BC018696-1|AAH18696.1| 509|Homo sapiens dihydrolipoamide dehydr... 185 1e-46
BC018648-1|AAH18648.1| 509|Homo sapiens dihydrolipoamide dehydr... 185 1e-46
AB209703-1|BAD92940.1| 520|Homo sapiens Dihydrolipoamide dehydr... 185 1e-46
L13761-1|AAB01381.1| 511|Homo sapiens dihydrolipoamide dehydrog... 181 2e-45
BC117354-1|AAI17355.1| 492|Homo sapiens TXNRD2 protein protein. 45 3e-04
BC007489-1|AAH07489.3| 485|Homo sapiens TXNRD2 protein protein. 45 3e-04
AF201385-1|AAG47635.1| 521|Homo sapiens mitochondrial thioredox... 45 3e-04
AF171054-1|AAD51324.1| 524|Homo sapiens thioredoxin reductase T... 45 3e-04
AF166127-1|AAF21432.1| 428|Homo sapiens selenoprotein Zf2 protein. 45 3e-04
AF166126-1|AAF21431.1| 277|Homo sapiens selenoprotein Zf1 protein. 45 3e-04
AF106697-1|AAD19597.1| 524|Homo sapiens thioredoxin reductase p... 45 3e-04
AF044212-1|AAD25167.1| 521|Homo sapiens thioredoxin reductase p... 45 3e-04
AB209724-1|BAD92961.1| 511|Homo sapiens thioredoxin reductase 2... 45 3e-04
AB019695-1|BAA77602.2| 494|Homo sapiens thioredoxin reductase I... 45 3e-04
AB019694-1|BAA77601.2| 524|Homo sapiens thioredoxin reductase I... 45 3e-04
X15722-1|CAA33744.1| 479|Homo sapiens protein ( Human mRNA for ... 44 4e-04
BC069244-1|AAH69244.1| 522|Homo sapiens glutathione reductase p... 44 4e-04
AY338490-1|AAP88037.1| 479|Homo sapiens glutathione reductase p... 44 4e-04
AF228704-1|AAF37574.1| 522|Homo sapiens mitochondrial glutathio... 44 4e-04
AF228703-2|AAF37573.1| 479|Homo sapiens cytosolic glutathione r... 44 4e-04
AF228703-1|AAF37572.1| 522|Homo sapiens mitochondrial glutathio... 44 4e-04
BC050032-1|AAH50032.1| 681|Homo sapiens TXNRD3 protein protein. 41 0.004
BC030028-1|AAH30028.1| 678|Homo sapiens TXNRD3 protein protein. 41 0.004
AF171055-1|AAD51325.1| 579|Homo sapiens thioredoxin reductase T... 41 0.004
AF133519-1|AAD39929.1| 577|Homo sapiens thioredoxin reductase 3... 41 0.004
X91247-1|CAA62629.1| 497|Homo sapiens thioredoxin reductase (NA... 39 0.017
S79851-1|AAB35418.1| 497|Homo sapiens thioredoxin reductase pro... 39 0.017
D88687-1|BAA13674.1| 549|Homo sapiens KM-102-derived reductase-... 39 0.017
DQ157758-1|AAZ67916.1| 497|Homo sapiens thioredoxin reductase 1... 39 0.017
CR536506-1|CAG38744.1| 497|Homo sapiens TXNRD1 protein. 39 0.017
BT019640-1|AAV38446.1| 497|Homo sapiens thioredoxin reductase 1... 39 0.017
BC018122-1|AAH18122.2| 499|Homo sapiens thioredoxin reductase 1... 39 0.017
AY057105-1|AAL15432.1| 647|Homo sapiens thioredoxin reductase 1... 39 0.017
AJ001050-1|CAA04503.1| 497|Homo sapiens thioredoxin reductase p... 39 0.017
AF208018-1|AAF15900.1| 497|Homo sapiens thioredoxin reductase p... 39 0.017
AF077367-1|AAC69621.1| 497|Homo sapiens thioredoxin reductase G... 38 0.022
AK128515-1|BAC87474.1| 581|Homo sapiens protein ( Homo sapiens ... 36 0.16
>J03620-1|AAA35764.1| 509|Homo sapiens protein ( Human
dihydrolipoamide dehydrogenase mRNA, complete cds. ).
Length = 509
Score = 185 bits (451), Expect = 1e-46
Identities = 83/117 (70%), Positives = 96/117 (82%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILG 419
IYT PEV WVGK+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG
Sbjct: 393 IYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLG 452
Query: 418 THIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 248
HI+GPG GE++NEA LA EYGA+ ED+ARVCHAHPT +EA REANLAA GK INF
Sbjct: 453 AHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF 509
>J03490-1|AAA59527.1| 509|Homo sapiens ZP3 protein.
Length = 509
Score = 185 bits (451), Expect = 1e-46
Identities = 83/117 (70%), Positives = 96/117 (82%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILG 419
IYT PEV WVGK+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG
Sbjct: 393 IYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLG 452
Query: 418 THIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 248
HI+GPG GE++NEA LA EYGA+ ED+ARVCHAHPT +EA REANLAA GK INF
Sbjct: 453 AHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF 509
>BC018696-1|AAH18696.1| 509|Homo sapiens dihydrolipoamide
dehydrogenase protein.
Length = 509
Score = 185 bits (451), Expect = 1e-46
Identities = 83/117 (70%), Positives = 96/117 (82%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILG 419
IYT PEV WVGK+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG
Sbjct: 393 IYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLG 452
Query: 418 THIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 248
HI+GPG GE++NEA LA EYGA+ ED+ARVCHAHPT +EA REANLAA GK INF
Sbjct: 453 AHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF 509
>BC018648-1|AAH18648.1| 509|Homo sapiens dihydrolipoamide
dehydrogenase protein.
Length = 509
Score = 185 bits (451), Expect = 1e-46
Identities = 83/117 (70%), Positives = 96/117 (82%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILG 419
IYT PEV WVGK+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG
Sbjct: 393 IYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLG 452
Query: 418 THIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 248
HI+GPG GE++NEA LA EYGA+ ED+ARVCHAHPT +EA REANLAA GK INF
Sbjct: 453 AHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF 509
>AB209703-1|BAD92940.1| 520|Homo sapiens Dihydrolipoamide
dehydrogenase, variant protein.
Length = 520
Score = 185 bits (451), Expect = 1e-46
Identities = 83/117 (70%), Positives = 96/117 (82%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILG 419
IYT PEV WVGK+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG
Sbjct: 404 IYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLG 463
Query: 418 THIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 248
HI+GPG GE++NEA LA EYGA+ ED+ARVCHAHPT +EA REANLAA GK INF
Sbjct: 464 AHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF 520
>L13761-1|AAB01381.1| 511|Homo sapiens dihydrolipoamide
dehydrogenase protein.
Length = 511
Score = 181 bits (441), Expect = 2e-45
Identities = 84/119 (70%), Positives = 96/119 (80%), Gaps = 2/119 (1%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILG 419
IYT PEV WVGK+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG
Sbjct: 393 IYTHPEVAWVGKSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLG 452
Query: 418 THIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTC--AEALREANLAAYSGKPINF 248
HI+GPG GE++NEA LA EYGA+ ED+ARVCHAHPT AEA REANLAA GK INF
Sbjct: 453 AHILGPGAGEMVNEAALALEYGASCEDIARVCHAHPTLSEAEAFREANLAASFGKSINF 511
>BC117354-1|AAI17355.1| 492|Homo sapiens TXNRD2 protein protein.
Length = 492
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTD 431
++T E G VG +EE+ + + G+ + G ++ +VK++ +
Sbjct: 369 VFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQ 428
Query: 430 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 263
++LG H +GP GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 429 LVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 484
>BC007489-1|AAH07489.3| 485|Homo sapiens TXNRD2 protein protein.
Length = 485
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTD 431
++T E G VG +EE+ + + G+ + G ++ +VK++ +
Sbjct: 360 VFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQ 419
Query: 430 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 263
++LG H +GP GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 420 LVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 475
>AF201385-1|AAG47635.1| 521|Homo sapiens mitochondrial thioredoxin
reductase protein.
Length = 521
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTD 431
++T E G VG +EE+ + + G+ + G ++ +VK++ +
Sbjct: 398 VFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQ 457
Query: 430 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 263
++LG H +GP GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 458 LVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 513
>AF171054-1|AAD51324.1| 524|Homo sapiens thioredoxin reductase TR3
protein.
Length = 524
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTD 431
++T E G VG +EE+ + + G+ + G ++ +VK++ +
Sbjct: 399 VFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQ 458
Query: 430 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 263
++LG H +GP GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 459 LVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 514
>AF166127-1|AAF21432.1| 428|Homo sapiens selenoprotein Zf2 protein.
Length = 428
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTD 431
++T E G VG +EE+ + + G+ + G ++ +VK++ +
Sbjct: 303 VFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQ 362
Query: 430 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 263
++LG H +GP GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 363 LVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 418
>AF166126-1|AAF21431.1| 277|Homo sapiens selenoprotein Zf1 protein.
Length = 277
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTD 431
++T E G VG +EE+ + + G+ + G ++ +VK++ +
Sbjct: 152 VFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQ 211
Query: 430 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 263
++LG H +GP GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 212 LVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 267
>AF106697-1|AAD19597.1| 524|Homo sapiens thioredoxin reductase
protein.
Length = 524
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTD 431
++T E G VG +EE+ + + G+ + G ++ +VK++ +
Sbjct: 399 VFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQ 458
Query: 430 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 263
++LG H +GP GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 459 LVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 514
>AF044212-1|AAD25167.1| 521|Homo sapiens thioredoxin reductase
protein.
Length = 521
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTD 431
++T E G VG +EE+ + + G+ + G ++ +VK++ +
Sbjct: 396 VFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQ 455
Query: 430 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 263
++LG H +GP GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 456 LVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 511
>AB209724-1|BAD92961.1| 511|Homo sapiens thioredoxin reductase 2
isoform 1 precursor variant protein.
Length = 511
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTD 431
++T E G VG +EE+ + + G+ + G ++ +VK++ +
Sbjct: 388 VFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQ 447
Query: 430 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 263
++LG H +GP GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 448 LVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 503
>AB019695-1|BAA77602.2| 494|Homo sapiens thioredoxin reductase II
beta protein.
Length = 494
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTD 431
++T E G VG +EE+ + + G+ + G ++ +VK++ +
Sbjct: 369 VFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQ 428
Query: 430 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 263
++LG H +GP GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 429 LVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 484
>AB019694-1|BAA77601.2| 524|Homo sapiens thioredoxin reductase II
alpha protein.
Length = 524
Score = 44.8 bits (101), Expect = 3e-04
Identities = 30/116 (25%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTD 431
++T E G VG +EE+ + + G+ + G ++ +VK++ +
Sbjct: 399 VFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQ 458
Query: 430 VILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 263
++LG H +GP GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 459 LVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 514
>X15722-1|CAA33744.1| 479|Homo sapiens protein ( Human mRNA for
glutathione reductase (EC 1.6.4.2). ).
Length = 479
Score = 44.0 bits (99), Expect = 4e-04
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVI 425
+++ P +G VG TE++ + K G K F A T +T+ +K++ + +
Sbjct: 372 VFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKV 431
Query: 424 LGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 293
+G H+ G G E++ +A + GA D HPT +E L
Sbjct: 432 VGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 475
>BC069244-1|AAH69244.1| 522|Homo sapiens glutathione reductase
protein.
Length = 522
Score = 44.0 bits (99), Expect = 4e-04
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVI 425
+++ P +G VG TE++ + K G K F A T +T+ +K++ + +
Sbjct: 415 VFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKV 474
Query: 424 LGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 293
+G H+ G G E++ +A + GA D HPT +E L
Sbjct: 475 VGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 518
>AY338490-1|AAP88037.1| 479|Homo sapiens glutathione reductase
protein.
Length = 479
Score = 44.0 bits (99), Expect = 4e-04
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVI 425
+++ P +G VG TE++ + K G K F A T +T+ +K++ + +
Sbjct: 372 VFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKV 431
Query: 424 LGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 293
+G H+ G G E++ +A + GA D HPT +E L
Sbjct: 432 VGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 475
>AF228704-1|AAF37574.1| 522|Homo sapiens mitochondrial glutathione
reductase protein.
Length = 522
Score = 44.0 bits (99), Expect = 4e-04
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVI 425
+++ P +G VG TE++ + K G K F A T +T+ +K++ + +
Sbjct: 415 VFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKV 474
Query: 424 LGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 293
+G H+ G G E++ +A + GA D HPT +E L
Sbjct: 475 VGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 518
>AF228703-2|AAF37573.1| 479|Homo sapiens cytosolic glutathione
reductase protein.
Length = 479
Score = 44.0 bits (99), Expect = 4e-04
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVI 425
+++ P +G VG TE++ + K G K F A T +T+ +K++ + +
Sbjct: 372 VFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKV 431
Query: 424 LGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 293
+G H+ G G E++ +A + GA D HPT +E L
Sbjct: 432 VGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 475
>AF228703-1|AAF37572.1| 522|Homo sapiens mitochondrial glutathione
reductase protein.
Length = 522
Score = 44.0 bits (99), Expect = 4e-04
Identities = 28/104 (26%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVI 425
+++ P +G VG TE++ + K G K F A T +T+ +K++ + +
Sbjct: 415 VFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKV 474
Query: 424 LGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 293
+G H+ G G E++ +A + GA D HPT +E L
Sbjct: 475 VGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 518
>BC050032-1|AAH50032.1| 681|Homo sapiens TXNRD3 protein protein.
Length = 681
Score = 40.7 bits (91), Expect = 0.004
Identities = 32/121 (26%), Positives = 49/121 (40%), Gaps = 6/121 (4%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEEDL----KKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT 434
++T E G G +EE KKE Y +P + N + K++ +K
Sbjct: 558 VFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTC--YAKIICNKFD 615
Query: 433 -DVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKP 257
D ++G HI+GP GE+ A + G + + HPTC E + SG
Sbjct: 616 HDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLD 675
Query: 256 I 254
I
Sbjct: 676 I 676
>BC030028-1|AAH30028.1| 678|Homo sapiens TXNRD3 protein protein.
Length = 678
Score = 40.7 bits (91), Expect = 0.004
Identities = 32/121 (26%), Positives = 49/121 (40%), Gaps = 6/121 (4%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEEDL----KKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT 434
++T E G G +EE KKE Y +P + N + K++ +K
Sbjct: 555 VFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTC--YAKIICNKFD 612
Query: 433 -DVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKP 257
D ++G HI+GP GE+ A + G + + HPTC E + SG
Sbjct: 613 HDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLD 672
Query: 256 I 254
I
Sbjct: 673 I 673
>AF171055-1|AAD51325.1| 579|Homo sapiens thioredoxin reductase TR2
protein.
Length = 579
Score = 40.7 bits (91), Expect = 0.004
Identities = 32/121 (26%), Positives = 49/121 (40%), Gaps = 6/121 (4%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEEDL----KKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT 434
++T E G G +EE KKE Y +P + N + K++ +K
Sbjct: 454 VFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTC--YAKIICNKFD 511
Query: 433 -DVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKP 257
D ++G HI+GP GE+ A + G + + HPTC E + SG
Sbjct: 512 HDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLD 571
Query: 256 I 254
I
Sbjct: 572 I 572
>AF133519-1|AAD39929.1| 577|Homo sapiens thioredoxin reductase 3
protein.
Length = 577
Score = 40.7 bits (91), Expect = 0.004
Identities = 32/121 (26%), Positives = 49/121 (40%), Gaps = 6/121 (4%)
Frame = -2
Query: 598 IYTSPEVGWVGKTEEDL----KKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT 434
++T E G G +EE KKE Y +P + N + K++ +K
Sbjct: 452 VFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTC--YAKIICNKFD 509
Query: 433 -DVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKP 257
D ++G HI+GP GE+ A + G + + HPTC E + SG
Sbjct: 510 HDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLD 569
Query: 256 I 254
I
Sbjct: 570 I 570
>X91247-1|CAA62629.1| 497|Homo sapiens thioredoxin reductase
(NADPH) protein.
Length = 497
Score = 38.7 bits (86), Expect = 0.017
Identities = 17/67 (25%), Positives = 30/67 (44%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 275
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485
Query: 274 AYSGKPI 254
SG I
Sbjct: 486 KRSGASI 492
>S79851-1|AAB35418.1| 497|Homo sapiens thioredoxin reductase
protein.
Length = 497
Score = 38.7 bits (86), Expect = 0.017
Identities = 17/67 (25%), Positives = 30/67 (44%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 275
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485
Query: 274 AYSGKPI 254
SG I
Sbjct: 486 KRSGASI 492
>D88687-1|BAA13674.1| 549|Homo sapiens KM-102-derived
reductase-like factor protein.
Length = 549
Score = 38.7 bits (86), Expect = 0.017
Identities = 17/67 (25%), Positives = 30/67 (44%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 275
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 478 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 537
Query: 274 AYSGKPI 254
SG I
Sbjct: 538 KRSGASI 544
>DQ157758-1|AAZ67916.1| 497|Homo sapiens thioredoxin reductase 1
protein.
Length = 497
Score = 38.7 bits (86), Expect = 0.017
Identities = 17/67 (25%), Positives = 30/67 (44%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 275
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485
Query: 274 AYSGKPI 254
SG I
Sbjct: 486 KRSGASI 492
>CR536506-1|CAG38744.1| 497|Homo sapiens TXNRD1 protein.
Length = 497
Score = 38.7 bits (86), Expect = 0.017
Identities = 17/67 (25%), Positives = 30/67 (44%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 275
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485
Query: 274 AYSGKPI 254
SG I
Sbjct: 486 KRSGASI 492
>BT019640-1|AAV38446.1| 497|Homo sapiens thioredoxin reductase 1
protein.
Length = 497
Score = 38.7 bits (86), Expect = 0.017
Identities = 17/67 (25%), Positives = 30/67 (44%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 275
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485
Query: 274 AYSGKPI 254
SG I
Sbjct: 486 KRSGASI 492
>BC018122-1|AAH18122.2| 499|Homo sapiens thioredoxin reductase 1
protein.
Length = 499
Score = 38.7 bits (86), Expect = 0.017
Identities = 17/67 (25%), Positives = 30/67 (44%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 275
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485
Query: 274 AYSGKPI 254
SG I
Sbjct: 486 KRSGASI 492
>AY057105-1|AAL15432.1| 647|Homo sapiens thioredoxin reductase 1
protein.
Length = 647
Score = 38.7 bits (86), Expect = 0.017
Identities = 17/67 (25%), Positives = 30/67 (44%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 275
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 576 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 635
Query: 274 AYSGKPI 254
SG I
Sbjct: 636 KRSGASI 642
>AJ001050-1|CAA04503.1| 497|Homo sapiens thioredoxin reductase
protein.
Length = 497
Score = 38.7 bits (86), Expect = 0.017
Identities = 17/67 (25%), Positives = 30/67 (44%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 275
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485
Query: 274 AYSGKPI 254
SG I
Sbjct: 486 KRSGASI 492
>AF208018-1|AAF15900.1| 497|Homo sapiens thioredoxin reductase
protein.
Length = 497
Score = 38.7 bits (86), Expect = 0.017
Identities = 17/67 (25%), Positives = 30/67 (44%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 275
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485
Query: 274 AYSGKPI 254
SG I
Sbjct: 486 KRSGASI 492
>AF077367-1|AAC69621.1| 497|Homo sapiens thioredoxin reductase
GRIM-12 protein.
Length = 497
Score = 38.3 bits (85), Expect = 0.022
Identities = 17/67 (25%), Positives = 30/67 (44%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLA 275
+ + K + ++G H++GP GE+ A + G + + HP CAE ++
Sbjct: 426 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVT 485
Query: 274 AYSGKPI 254
SG I
Sbjct: 486 KRSGARI 492
>AK128515-1|BAC87474.1| 581|Homo sapiens protein ( Homo sapiens
cDNA FLJ46672 fis, clone TRACH3009008, highly similar
to Thioredoxin reductase (EC 1.6.4.5). ).
Length = 581
Score = 35.5 bits (78), Expect = 0.16
Identities = 14/52 (26%), Positives = 25/52 (48%)
Frame = -2
Query: 454 VLSDKTTDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 299
+ + K + ++G H++GP GE+ A + G + + HP CAE
Sbjct: 525 ICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE 576
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 84,476,076
Number of Sequences: 237096
Number of extensions: 1586330
Number of successful extensions: 3686
Number of sequences better than 10.0: 39
Number of HSP's better than 10.0 without gapping: 3444
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3685
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6860268620
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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