Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmmt12o12
(666 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 85 2e-16
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 85 2e-16
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 85 2e-16
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 85 2e-16
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 79 1e-14
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 79 1e-14
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 79 1e-14
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 79 1e-14
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 79 1e-14
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 79 1e-14
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 79 1e-14
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 77 8e-14
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 76 1e-13
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 76 1e-13
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 76 1e-13
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 76 1e-13
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 76 1e-13
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 76 1e-13
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 76 1e-13
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 76 1e-13
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 76 1e-13
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 76 1e-13
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 75 2e-13
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 75 2e-13
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 75 2e-13
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 75 2e-13
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 75 2e-13
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 75 2e-13
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 75 2e-13
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 75 2e-13
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 75 2e-13
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 75 2e-13
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 74 5e-13
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 74 5e-13
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 74 5e-13
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 74 5e-13
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 74 5e-13
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 73 9e-13
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 73 1e-12
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 73 1e-12
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 73 1e-12
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 72 2e-12
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 72 2e-12
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 72 2e-12
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 72 2e-12
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 72 2e-12
BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family... 71 4e-12
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 71 4e-12
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 71 5e-12
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 71 5e-12
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 71 5e-12
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 71 5e-12
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 69 1e-11
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 69 1e-11
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 69 1e-11
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 69 1e-11
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 69 1e-11
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 69 1e-11
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 69 2e-11
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 69 2e-11
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 69 2e-11
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 69 2e-11
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 69 2e-11
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 69 2e-11
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 69 2e-11
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 69 2e-11
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 69 2e-11
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 69 2e-11
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 69 2e-11
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 68 3e-11
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 68 3e-11
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 68 3e-11
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 68 3e-11
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 68 3e-11
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 68 3e-11
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 68 3e-11
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 68 3e-11
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 68 3e-11
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 68 3e-11
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 68 3e-11
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 68 3e-11
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 68 3e-11
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 68 3e-11
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 68 3e-11
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 68 3e-11
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 68 3e-11
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 68 3e-11
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 68 3e-11
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 68 3e-11
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 68 3e-11
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 68 3e-11
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 68 3e-11
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 68 3e-11
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 68 3e-11
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 68 3e-11
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 68 3e-11
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 68 3e-11
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 67 5e-11
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 67 5e-11
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 67 5e-11
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 67 5e-11
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 67 5e-11
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 67 5e-11
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 67 5e-11
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 67 5e-11
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 67 6e-11
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 67 6e-11
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 67 6e-11
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 67 6e-11
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 65 2e-10
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 65 2e-10
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 64 3e-10
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 64 6e-10
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 64 6e-10
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 64 6e-10
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 64 6e-10
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 63 7e-10
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 62 2e-09
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 62 2e-09
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 62 2e-09
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 62 2e-09
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 62 2e-09
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 62 2e-09
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 62 2e-09
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 62 2e-09
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 62 2e-09
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 61 3e-09
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 61 3e-09
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 61 4e-09
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 61 4e-09
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 61 4e-09
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 61 4e-09
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 61 4e-09
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 61 4e-09
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 61 4e-09
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 61 4e-09
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 61 4e-09
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 60 5e-09
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 60 5e-09
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 60 7e-09
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 60 7e-09
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 60 7e-09
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 60 7e-09
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 60 7e-09
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 60 7e-09
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 60 7e-09
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 60 9e-09
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 60 9e-09
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 60 9e-09
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 60 9e-09
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 59 1e-08
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 58 2e-08
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 58 3e-08
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 58 3e-08
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 57 5e-08
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 57 5e-08
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 57 5e-08
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 57 5e-08
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 57 5e-08
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 57 5e-08
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 57 5e-08
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 57 5e-08
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 57 5e-08
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 57 5e-08
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 56 9e-08
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 56 9e-08
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 56 9e-08
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 56 9e-08
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 56 9e-08
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 56 9e-08
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 56 9e-08
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 56 9e-08
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 56 9e-08
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 56 9e-08
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 56 9e-08
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 56 9e-08
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 56 9e-08
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 56 9e-08
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 56 9e-08
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 56 9e-08
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 56 9e-08
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 56 9e-08
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 56 9e-08
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 56 9e-08
AM233518-1|CAJ80721.1| 157|Homo sapiens cytochrome P450 1A1 pro... 56 9e-08
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 56 9e-08
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 56 9e-08
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 56 9e-08
AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1 pro... 56 9e-08
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 56 1e-07
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 56 1e-07
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 56 2e-07
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 56 2e-07
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 56 2e-07
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 55 2e-07
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 55 2e-07
S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 55 2e-07
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 55 2e-07
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 55 2e-07
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 55 2e-07
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 55 2e-07
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 55 2e-07
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 55 2e-07
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 55 3e-07
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 55 3e-07
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 55 3e-07
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 55 3e-07
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 55 3e-07
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 55 3e-07
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 55 3e-07
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 54 3e-07
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 54 3e-07
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 54 3e-07
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 54 3e-07
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 54 3e-07
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 54 3e-07
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 54 3e-07
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 54 3e-07
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 54 3e-07
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 54 3e-07
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 54 3e-07
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 54 3e-07
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 54 3e-07
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 54 3e-07
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 54 3e-07
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 54 3e-07
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 54 3e-07
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 54 5e-07
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 54 5e-07
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 54 5e-07
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 54 5e-07
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 54 5e-07
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 54 5e-07
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 54 6e-07
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 54 6e-07
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 52 1e-06
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 52 2e-06
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 52 2e-06
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 52 2e-06
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 52 2e-06
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 52 2e-06
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 52 2e-06
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 51 4e-06
AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens ... 50 6e-06
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 50 7e-06
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 50 1e-05
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 50 1e-05
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 50 1e-05
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 50 1e-05
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 50 1e-05
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 49 1e-05
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 1e-05
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 1e-05
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 1e-05
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 1e-05
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 1e-05
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 1e-05
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 49 1e-05
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 49 1e-05
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 49 1e-05
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 49 1e-05
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 49 1e-05
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 49 1e-05
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 48 2e-05
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 48 2e-05
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 48 2e-05
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 2e-05
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 2e-05
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 48 2e-05
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 2e-05
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 2e-05
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 2e-05
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 2e-05
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 2e-05
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 48 2e-05
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 48 2e-05
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 48 2e-05
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 48 2e-05
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 48 2e-05
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 48 3e-05
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 48 4e-05
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 48 4e-05
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 48 4e-05
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 47 5e-05
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 47 5e-05
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 47 5e-05
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 47 7e-05
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 47 7e-05
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 47 7e-05
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 46 9e-05
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 46 9e-05
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 46 9e-05
X58899-1|CAA41703.1| 368|Homo sapiens steroid 21-monooxygenase ... 46 9e-05
X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase ... 46 9e-05
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 46 9e-05
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 46 9e-05
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 46 9e-05
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 46 9e-05
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 46 9e-05
BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 46 9e-05
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 46 9e-05
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 46 9e-05
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 46 9e-05
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 46 9e-05
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 46 9e-05
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 46 9e-05
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 46 9e-05
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 46 9e-05
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 46 9e-05
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 46 9e-05
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 46 9e-05
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 46 9e-05
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 46 9e-05
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 46 9e-05
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 46 9e-05
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 46 9e-05
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 46 9e-05
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 46 9e-05
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 46 1e-04
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 46 1e-04
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 46 1e-04
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 46 1e-04
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 46 1e-04
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 46 1e-04
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 46 2e-04
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 46 2e-04
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 46 2e-04
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 46 2e-04
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 46 2e-04
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 46 2e-04
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 46 2e-04
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 46 2e-04
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 46 2e-04
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 46 2e-04
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 46 2e-04
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 46 2e-04
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 46 2e-04
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 46 2e-04
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 46 2e-04
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 46 2e-04
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 46 2e-04
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 46 2e-04
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 46 2e-04
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 45 2e-04
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 45 2e-04
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 45 3e-04
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 45 3e-04
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 45 3e-04
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 45 3e-04
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 45 3e-04
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 45 3e-04
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 45 3e-04
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 45 3e-04
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 45 3e-04
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 45 3e-04
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 45 3e-04
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 45 3e-04
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 44 4e-04
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 44 4e-04
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 44 4e-04
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 44 4e-04
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 44 4e-04
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 44 4e-04
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 44 4e-04
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 44 4e-04
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 44 4e-04
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 44 4e-04
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 44 4e-04
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 44 5e-04
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 44 5e-04
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 44 5e-04
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 44 5e-04
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 44 5e-04
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 43 9e-04
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 42 0.003
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 42 0.003
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 41 0.003
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 41 0.003
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 41 0.003
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 41 0.005
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 41 0.005
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 41 0.005
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 41 0.005
BC056258-1|AAH56258.1| 359|Homo sapiens CYP19A1 protein protein. 40 0.008
BC020767-1|AAH20767.1| 360|Homo sapiens Unknown (protein for IM... 40 0.008
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 39 0.018
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 39 0.018
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 39 0.018
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 39 0.018
AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 39 0.018
AC005336-2|AAC27731.1| 93|Homo sapiens F20191_1, partial CDS p... 37 0.056
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 36 0.13
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 36 0.13
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 36 0.13
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 36 0.13
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 36 0.17
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 36 0.17
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 36 0.17
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 36 0.17
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 36 0.17
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 36 0.17
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 35 0.30
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 34 0.40
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 34 0.40
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 34 0.40
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 34 0.40
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 34 0.40
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 33 0.69
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 33 0.69
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 33 0.92
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 33 0.92
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 33 0.92
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 33 0.92
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 33 0.92
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 33 0.92
BC067444-1|AAH67444.1| 501|Homo sapiens cytochrome P450, family... 31 2.8
BC067442-1|AAH67442.1| 501|Homo sapiens cytochrome P450, family... 31 2.8
BC067441-1|AAH67441.1| 501|Homo sapiens cytochrome P450, family... 31 2.8
BC067434-1|AAH67434.1| 501|Homo sapiens cytochrome P450, family... 31 2.8
AF090320-1|AAD19877.1| 501|Homo sapiens sterol 12-alpha-hydroxy... 31 2.8
AF090318-1|AAC63037.1| 462|Homo sapiens sterol 12-alpha hydroxy... 31 2.8
BC064414-1|AAH64414.1| 157|Homo sapiens Unknown (protein for IM... 31 4.9
AY679523-1|AAT74623.1| 1512|Homo sapiens cell division cycle 2-l... 31 4.9
AJ297710-1|CAC10401.1| 1452|Homo sapiens CDC2L5 protein kinase p... 31 4.9
AJ297709-1|CAC10400.1| 1512|Homo sapiens CDC2L5 protein kinase p... 31 4.9
AC072061-1|AAS07491.1| 784|Homo sapiens unknown protein. 31 4.9
BC035760-1|AAH35760.1| 595|Homo sapiens ZNF440 protein protein. 30 6.5
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 30 6.5
AK095252-1|BAC04510.1| 595|Homo sapiens protein ( Homo sapiens ... 30 6.5
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 85.4 bits (202), Expect = 2e-16
Identities = 43/136 (31%), Positives = 75/136 (55%), Gaps = 4/136 (2%)
Frame = -1
Query: 633 GTQDYSGEQKPFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGS 460
G+ +++ F+DL + + +++G LS ++ E+ TF+ GHDT + ++L +GS
Sbjct: 288 GSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGS 347
Query: 459 HPPVQQRIYEELQQVLGSDD--VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQ+++ EL V G D T ++L L YLE IKET+RL+P P+ +R D +
Sbjct: 348 NPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCE 407
Query: 285 LRNSTIPSGASVALSP 238
+ + G + P
Sbjct: 408 VAGYRVLKGTEAVIIP 423
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 4/88 (4%)
Frame = -2
Query: 254 VSLCLHHHPVWGSDVEHFKPERWLDPTTLPEN--AFAGFSTGKRNCIGKTFAMMSMKTTL 81
+ LH P + + E F+PER+ + A+ FS G RNCIG+ FA+M KT L
Sbjct: 422 IPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTIL 481
Query: 80 AHLLRQYRVTADITRMEAKLD--IILKP 3
+ +LR + + ++ R E L+ +IL+P
Sbjct: 482 SCILRHFWIESNQKREELGLEGQLILRP 509
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 85.4 bits (202), Expect = 2e-16
Identities = 43/136 (31%), Positives = 75/136 (55%), Gaps = 4/136 (2%)
Frame = -1
Query: 633 GTQDYSGEQKPFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGS 460
G+ +++ F+DL + + +++G LS ++ E+ TF+ GHDT + ++L +GS
Sbjct: 288 GSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGS 347
Query: 459 HPPVQQRIYEELQQVLGSDD--VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQ+++ EL V G D T ++L L YLE IKET+RL+P P+ +R D +
Sbjct: 348 NPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCE 407
Query: 285 LRNSTIPSGASVALSP 238
+ + G + P
Sbjct: 408 VAGYRVLKGTEAVIIP 423
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 4/88 (4%)
Frame = -2
Query: 254 VSLCLHHHPVWGSDVEHFKPERWLDPTTLPEN--AFAGFSTGKRNCIGKTFAMMSMKTTL 81
+ LH P + + E F+PER+ + A+ FS G RNCIG+ FA+M KT L
Sbjct: 422 IPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTIL 481
Query: 80 AHLLRQYRVTADITRMEAKLD--IILKP 3
+ +LR + + ++ R E L+ +IL+P
Sbjct: 482 SCILRHFWIESNQKREELGLEGQLILRP 509
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 85.4 bits (202), Expect = 2e-16
Identities = 43/136 (31%), Positives = 75/136 (55%), Gaps = 4/136 (2%)
Frame = -1
Query: 633 GTQDYSGEQKPFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGS 460
G+ +++ F+DL + + +++G LS ++ E+ TF+ GHDT + ++L +GS
Sbjct: 266 GSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGS 325
Query: 459 HPPVQQRIYEELQQVLGSDD--VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQ+++ EL V G D T ++L L YLE IKET+RL+P P+ +R D +
Sbjct: 326 NPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCE 385
Query: 285 LRNSTIPSGASVALSP 238
+ + G + P
Sbjct: 386 VAGYRVLKGTEAVIIP 401
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 4/88 (4%)
Frame = -2
Query: 254 VSLCLHHHPVWGSDVEHFKPERWLDPTTLPEN--AFAGFSTGKRNCIGKTFAMMSMKTTL 81
+ LH P + + E F+PER+ + A+ FS G RNCIG+ FA+M KT L
Sbjct: 400 IPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTIL 459
Query: 80 AHLLRQYRVTADITRMEAKLD--IILKP 3
+ +LR + + ++ R E L+ +IL+P
Sbjct: 460 SCILRHFWIESNQKREELGLEGQLILRP 487
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 85.4 bits (202), Expect = 2e-16
Identities = 43/136 (31%), Positives = 75/136 (55%), Gaps = 4/136 (2%)
Frame = -1
Query: 633 GTQDYSGEQKPFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGS 460
G+ +++ F+DL + + +++G LS ++ E+ TF+ GHDT + ++L +GS
Sbjct: 288 GSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGS 347
Query: 459 HPPVQQRIYEELQQVLGSDD--VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQ+++ EL V G D T ++L L YLE IKET+RL+P P+ +R D +
Sbjct: 348 NPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCE 407
Query: 285 LRNSTIPSGASVALSP 238
+ + G + P
Sbjct: 408 VAGYRVLKGTEAVIIP 423
Score = 55.6 bits (128), Expect = 2e-07
Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 4/88 (4%)
Frame = -2
Query: 254 VSLCLHHHPVWGSDVEHFKPERWLDPTTLPEN--AFAGFSTGKRNCIGKTFAMMSMKTTL 81
+ LH P + + E F+PER+ + A+ FS G RNCIG+ FA+M KT L
Sbjct: 422 IPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTIL 481
Query: 80 AHLLRQYRVTADITRMEAKLD--IILKP 3
+ +LR + + ++ R E L+ +IL+P
Sbjct: 482 SCILRHFWIESNQKREELGLEGQLILRP 509
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 79.4 bits (187), Expect = 1e-14
Identities = 46/135 (34%), Positives = 76/135 (56%), Gaps = 6/135 (4%)
Frame = -1
Query: 627 QDYSGEQK--PFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGS 460
QD + ++K F+D+ + +E G SD++V E++TF+ AGHDT+ ++ + L C+
Sbjct: 275 QDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLAL 334
Query: 459 HPPVQQRIYEELQQVLG-SDDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKL 283
+P Q+R EE++ +LG +T L + Y IKET RL P P +SR +
Sbjct: 335 NPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 394
Query: 282 RNS-TIPSGASVALS 241
+ T+P+G +V LS
Sbjct: 395 PDGCTLPAGITVVLS 409
Score = 57.6 bits (133), Expect = 4e-08
Identities = 33/83 (39%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFA--GFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH+P + + F P R+ + + +A FS G RNCIG+ FAM+ +K T+A +L
Sbjct: 413 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 472
Query: 68 RQYRVTADITR-MEAKLDIILKP 3
+RVT D TR + ILKP
Sbjct: 473 LHFRVTPDPTRPLTFPNHFILKP 495
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 79.4 bits (187), Expect = 1e-14
Identities = 46/135 (34%), Positives = 76/135 (56%), Gaps = 6/135 (4%)
Frame = -1
Query: 627 QDYSGEQK--PFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGS 460
QD + ++K F+D+ + +E G SD++V E++TF+ AGHDT+ ++ + L C+
Sbjct: 275 QDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLAL 334
Query: 459 HPPVQQRIYEELQQVLG-SDDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKL 283
+P Q+R EE++ +LG +T L + Y IKET RL P P +SR +
Sbjct: 335 NPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 394
Query: 282 RNS-TIPSGASVALS 241
+ T+P+G +V LS
Sbjct: 395 PDGCTLPAGITVVLS 409
Score = 57.6 bits (133), Expect = 4e-08
Identities = 33/83 (39%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFA--GFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH+P + + F P R+ + + +A FS G RNCIG+ FAM+ +K T+A +L
Sbjct: 413 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 472
Query: 68 RQYRVTADITR-MEAKLDIILKP 3
+RVT D TR + ILKP
Sbjct: 473 LHFRVTPDPTRPLTFPNHFILKP 495
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 79.4 bits (187), Expect = 1e-14
Identities = 46/135 (34%), Positives = 76/135 (56%), Gaps = 6/135 (4%)
Frame = -1
Query: 627 QDYSGEQK--PFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGS 460
QD + ++K F+D+ + +E G SD++V E++TF+ AGHDT+ ++ + L C+
Sbjct: 275 QDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLAL 334
Query: 459 HPPVQQRIYEELQQVLG-SDDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKL 283
+P Q+R EE++ +LG +T L + Y IKET RL P P +SR +
Sbjct: 335 NPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 394
Query: 282 RNS-TIPSGASVALS 241
+ T+P+G +V LS
Sbjct: 395 PDGCTLPAGITVVLS 409
Score = 57.6 bits (133), Expect = 4e-08
Identities = 33/83 (39%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFA--GFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH+P + + F P R+ + + +A FS G RNCIG+ FAM+ +K T+A +L
Sbjct: 413 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 472
Query: 68 RQYRVTADITR-MEAKLDIILKP 3
+RVT D TR + ILKP
Sbjct: 473 LHFRVTPDPTRPLTFPNHFILKP 495
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 79.4 bits (187), Expect = 1e-14
Identities = 46/135 (34%), Positives = 76/135 (56%), Gaps = 6/135 (4%)
Frame = -1
Query: 627 QDYSGEQK--PFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGS 460
QD + ++K F+D+ + +E G SD++V E++TF+ AGHDT+ ++ + L C+
Sbjct: 275 QDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLAL 334
Query: 459 HPPVQQRIYEELQQVLG-SDDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKL 283
+P Q+R EE++ +LG +T L + Y IKET RL P P +SR +
Sbjct: 335 NPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 394
Query: 282 RNS-TIPSGASVALS 241
+ T+P+G +V LS
Sbjct: 395 PDGCTLPAGITVVLS 409
Score = 57.6 bits (133), Expect = 4e-08
Identities = 33/83 (39%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFA--GFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH+P + + F P R+ + + +A FS G RNCIG+ FAM+ +K T+A +L
Sbjct: 413 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 472
Query: 68 RQYRVTADITR-MEAKLDIILKP 3
+RVT D TR + ILKP
Sbjct: 473 LHFRVTPDPTRPLTFPNHFILKP 495
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 79.4 bits (187), Expect = 1e-14
Identities = 46/135 (34%), Positives = 76/135 (56%), Gaps = 6/135 (4%)
Frame = -1
Query: 627 QDYSGEQK--PFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGS 460
QD + ++K F+D+ + +E G SD++V E++TF+ AGHDT+ ++ + L C+
Sbjct: 274 QDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLAL 333
Query: 459 HPPVQQRIYEELQQVLG-SDDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKL 283
+P Q+R EE++ +LG +T L + Y IKET RL P P +SR +
Sbjct: 334 NPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 393
Query: 282 RNS-TIPSGASVALS 241
+ T+P+G +V LS
Sbjct: 394 PDGCTLPAGITVVLS 408
Score = 57.6 bits (133), Expect = 4e-08
Identities = 33/83 (39%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFA--GFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH+P + + F P R+ + + +A FS G RNCIG+ FAM+ +K T+A +L
Sbjct: 412 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 471
Query: 68 RQYRVTADITR-MEAKLDIILKP 3
+RVT D TR + ILKP
Sbjct: 472 LHFRVTPDPTRPLTFPNHFILKP 494
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 79.4 bits (187), Expect = 1e-14
Identities = 46/135 (34%), Positives = 76/135 (56%), Gaps = 6/135 (4%)
Frame = -1
Query: 627 QDYSGEQK--PFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGS 460
QD + ++K F+D+ + +E G SD++V E++TF+ AGHDT+ ++ + L C+
Sbjct: 275 QDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLAL 334
Query: 459 HPPVQQRIYEELQQVLG-SDDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKL 283
+P Q+R EE++ +LG +T L + Y IKET RL P P +SR +
Sbjct: 335 NPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 394
Query: 282 RNS-TIPSGASVALS 241
+ T+P+G +V LS
Sbjct: 395 PDGCTLPAGITVVLS 409
Score = 57.6 bits (133), Expect = 4e-08
Identities = 33/83 (39%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFA--GFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH+P + + F P R+ + + +A FS G RNCIG+ FAM+ +K T+A +L
Sbjct: 413 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 472
Query: 68 RQYRVTADITR-MEAKLDIILKP 3
+RVT D TR + ILKP
Sbjct: 473 LHFRVTPDPTRPLTFPNHFILKP 495
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 79.4 bits (187), Expect = 1e-14
Identities = 46/135 (34%), Positives = 76/135 (56%), Gaps = 6/135 (4%)
Frame = -1
Query: 627 QDYSGEQK--PFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGS 460
QD + ++K F+D+ + +E G SD++V E++TF+ AGHDT+ ++ + L C+
Sbjct: 210 QDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLAL 269
Query: 459 HPPVQQRIYEELQQVLG-SDDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKL 283
+P Q+R EE++ +LG +T L + Y IKET RL P P +SR +
Sbjct: 270 NPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTF 329
Query: 282 RNS-TIPSGASVALS 241
+ T+P+G +V LS
Sbjct: 330 PDGCTLPAGITVVLS 344
Score = 57.6 bits (133), Expect = 4e-08
Identities = 33/83 (39%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFA--GFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH+P + + F P R+ + + +A FS G RNCIG+ FAM+ +K T+A +L
Sbjct: 348 LHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALIL 407
Query: 68 RQYRVTADITR-MEAKLDIILKP 3
+RVT D TR + ILKP
Sbjct: 408 LHFRVTPDPTRPLTFPNHFILKP 430
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 76.6 bits (180), Expect = 8e-14
Identities = 39/112 (34%), Positives = 63/112 (56%), Gaps = 1/112 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
E K LSD+E++ + I A +DT TL + + + +HP VQQ++ EE+ VL +
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLANK 342
Query: 402 -DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
VT L + YL+ + ET+RL+P+ V+RV D+++ IP G +V
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAV 394
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH P + ++ E F PER+ + ++ + F G RNCIG FA+ ++K + L
Sbjct: 401 LHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRAL 460
Query: 68 RQYRV-TADITRMEAKLD 18
+ + T++ KLD
Sbjct: 461 QNFSFKPCKETQIPLKLD 478
>BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein.
Length = 280
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + I A +DT TL + + + +HP VQQ++ EE+ VL
Sbjct: 143 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 202
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
VT L + YL+ + ET+RL+P+ V+RV D+++ IP G +V
Sbjct: 203 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAV 254
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + I A +DT TL + + + +HP VQQ++ EE+ VL
Sbjct: 173 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 232
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
VT L + YL+ + ET+RL+P+ V+RV D+++ IP G +V
Sbjct: 233 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAV 284
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH P + ++ E F PER+ + ++ + F G RNCIG FA+ ++K + L
Sbjct: 291 LHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRAL 350
Query: 68 RQYRV-TADITRMEAKLD 18
+ + T++ KLD
Sbjct: 351 QNFSFKPCKETQIPLKLD 368
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + I A +DT TL + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
VT L + YL+ + ET+RL+P+ V+RV D+++ IP G +V
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAV 394
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH P + ++ E F PER+ + ++ + F G RNCIG FA+ ++K + L
Sbjct: 401 LHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRAL 460
Query: 68 RQYRV-TADITRMEAKLD 18
+ + T++ KLD
Sbjct: 461 QNFSFKPCKETQIPLKLD 478
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + I A +DT TL + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
VT L + YL+ + ET+RL+P+ V+RV D+++ IP G +V
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAV 394
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH P + ++ E F PER+ + ++ + F G RNCIG FA+ ++K + L
Sbjct: 401 LHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRAL 460
Query: 68 RQYRV-TADITRMEAKLD 18
+ + T++ KLD
Sbjct: 461 QNFSFKPCKETQIPLKLD 478
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + I A +DT TL + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
VT L + YL+ + ET+RL+P+ V+RV D+++ IP G +V
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAV 394
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH P + ++ E F PER+ + ++ + F G RNCIG FA+ ++K + L
Sbjct: 401 LHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRAL 460
Query: 68 RQYRV-TADITRMEAKLD 18
+ + T++ KLD
Sbjct: 461 QNFSFKPCKETQIPLKLD 478
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + I A +DT TL + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
VT L + YL+ + ET+RL+P+ V+RV D+++ IP G +V
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAV 394
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + I A +DT TL + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
VT L + YL+ + ET+RL+P+ V+RV D+++ IP G +V
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAV 394
Score = 38.3 bits (85), Expect = 0.024
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL---DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHL 72
LHH P + ++ E F PE + ++ + F G RNCIG FA+ ++K +
Sbjct: 401 LHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRA 460
Query: 71 LRQYRV-TADITRMEAKLD 18
L+ + T++ KLD
Sbjct: 461 LQNFSFKPCKETQIPLKLD 479
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + I A +DT TL + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
VT L + YL+ + ET+RL+P+ V+RV D+++ IP G +V
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAV 394
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH P + ++ E F PER+ + ++ + F G RNCIG FA+ ++K + L
Sbjct: 401 LHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRAL 460
Query: 68 RQYRV-TADITRMEAKLD 18
+ + T++ KLD
Sbjct: 461 QNFSFKPCKETQIPLKLD 478
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + I A +DT TL + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
VT L + YL+ + ET+RL+P+ V+RV D+++ IP G +V
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAV 394
Score = 38.3 bits (85), Expect = 0.024
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL---DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHL 72
LHH P + ++ E F PE + ++ + F G RNCIG FA+ ++K +
Sbjct: 401 LHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRA 460
Query: 71 LRQYRV-TADITRMEAKLD 18
L+ + T++ KLD
Sbjct: 461 LQNFSFKPCKETQIPLKLD 479
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 75.8 bits (178), Expect = 1e-13
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + I A +DT TL + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
VT L + YL+ + ET+RL+P+ V+RV D+++ IP G +V
Sbjct: 343 APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAV 394
Score = 42.3 bits (95), Expect = 0.001
Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH P + ++ E F PER+ + ++ + F G RNCIG FA+ ++K + L
Sbjct: 401 LHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRAL 460
Query: 68 RQYRV-TADITRMEAKLD 18
+ + T++ KLD
Sbjct: 461 QNFSFKPCKETQIPLKLD 478
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+PIA + RV DV++ IP G V +
Sbjct: 343 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 398 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+PIA + RV DV++ IP G V +
Sbjct: 343 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 398 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+PIA + RV DV++ IP G V +
Sbjct: 343 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 398 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+PIA + RV DV++ IP G V +
Sbjct: 343 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 398 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+PIA + RV DV++ IP G V +
Sbjct: 343 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 398 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 133 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 192
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+PIA + RV DV++ IP G V +
Sbjct: 193 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI 246
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 248 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 307
Query: 77 HLLRQY 60
+L+ +
Sbjct: 308 RVLQNF 313
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 210 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 269
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+PIA + RV DV++ IP G V +
Sbjct: 270 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI 323
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 325 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 384
Query: 77 HLLRQY 60
+L+ +
Sbjct: 385 RVLQNF 390
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+PIA + RV DV++ IP G V +
Sbjct: 343 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 398 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+PIA + RV DV++ IP G V +
Sbjct: 343 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 398 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 74.9 bits (176), Expect = 2e-13
Identities = 39/114 (34%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+PIA + RV DV++ IP G V +
Sbjct: 343 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 398 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 73.7 bits (173), Expect = 5e-13
Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSG 259
T + + YL+ + ET+RL+PIA + RV DV++ IP G
Sbjct: 343 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKG 391
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 398 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 73.7 bits (173), Expect = 5e-13
Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSG 259
T + + YL+ + ET+RL+PIA + RV DV++ IP G
Sbjct: 343 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKG 391
Score = 47.6 bits (108), Expect = 4e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 398 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALI 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 73.7 bits (173), Expect = 5e-13
Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 284 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 343
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSG 259
T + + YL+ + ET+RL+PIA + RV DV++ IP G
Sbjct: 344 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKG 392
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 399 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 458
Query: 77 HLLRQY 60
+L+ +
Sbjct: 459 RVLQNF 464
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 73.7 bits (173), Expect = 5e-13
Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 282 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 341
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSG 259
T + + YL+ + ET+RL+PIA + RV DV++ IP G
Sbjct: 342 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKG 390
Score = 47.6 bits (108), Expect = 4e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 397 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALI 456
Query: 77 HLLRQY 60
+L+ +
Sbjct: 457 RVLQNF 462
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 73.7 bits (173), Expect = 5e-13
Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG++T L + + + +HP VQQ++ EE+ VL
Sbjct: 284 ETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 343
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSG 259
T + + YL+ + ET+RL+PIA + RV DV++ IP G
Sbjct: 344 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKG 392
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 399 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 458
Query: 77 HLLRQY 60
+L+ +
Sbjct: 459 RVLQNF 464
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 72.9 bits (171), Expect = 9e-13
Identities = 39/114 (34%), Positives = 61/114 (53%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E++ + FI AG +T L + + + +HP VQQ++ EE+ VL
Sbjct: 283 ETESHKALSDLELVAQSIIFIFAGCETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+PIA + RV DV++ IP G V +
Sbjct: 343 APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 47.2 bits (107), Expect = 5e-05
Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LH P + ++ E F PER+ + + + F +G RNCIG FA+M+MK L
Sbjct: 398 SYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALI 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 72.5 bits (170), Expect = 1e-12
Identities = 38/114 (33%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E+ + FI AG++T L +TL + +HP VQQ++ +E+ VL
Sbjct: 283 ETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+P+A + R DV++ IP G+ V +
Sbjct: 343 APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVI 396
Score = 54.0 bits (124), Expect = 5e-07
Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPT-TLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLR 66
LHH P + ++ E F+PER+ ++ + F TG RNCIG FA+M+MK L +L+
Sbjct: 401 LHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQ 460
Query: 65 QYRV-TADITRMEAKLD 18
+ T++ KLD
Sbjct: 461 NFSFKPCKETQIPLKLD 477
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 72.5 bits (170), Expect = 1e-12
Identities = 38/114 (33%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E+ + FI AG++T L +TL + +HP VQQ++ +E+ VL
Sbjct: 283 ETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+P+A + R DV++ IP G+ V +
Sbjct: 343 APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVI 396
Score = 54.0 bits (124), Expect = 5e-07
Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPT-TLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLR 66
LHH P + ++ E F+PER+ ++ + F TG RNCIG FA+M+MK L +L+
Sbjct: 401 LHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQ 460
Query: 65 QYRV-TADITRMEAKLD 18
+ T++ KLD
Sbjct: 461 NFSFKPCKETQIPLKLD 477
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 72.5 bits (170), Expect = 1e-12
Identities = 38/114 (33%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E+ + FI AG++T L +TL + +HP VQQ++ +E+ VL
Sbjct: 283 ETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+P+A + R DV++ IP G+ V +
Sbjct: 343 APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVI 396
Score = 54.0 bits (124), Expect = 5e-07
Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPT-TLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLR 66
LHH P + ++ E F+PER+ ++ + F TG RNCIG FA+M+MK L +L+
Sbjct: 401 LHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQ 460
Query: 65 QYRV-TADITRMEAKLD 18
+ T++ KLD
Sbjct: 461 NFSFKPCKETQIPLKLD 477
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 72.1 bits (169), Expect = 2e-12
Identities = 37/109 (33%), Positives = 61/109 (55%), Gaps = 1/109 (0%)
Frame = -1
Query: 567 KGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GSDDVTK 391
K LSD+E++ + FI AG++T L + + + +HP VQQ++ +E+ VL T
Sbjct: 288 KALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTY 347
Query: 390 QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
+ L YL+ + ET+RL+P+A + RV DV++ IP G V +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 48.8 bits (111), Expect = 2e-05
Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LHH P + ++ E F PER+ + + + F +G RNCIG FA+++MK L
Sbjct: 398 SYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALV 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 72.1 bits (169), Expect = 2e-12
Identities = 37/109 (33%), Positives = 61/109 (55%), Gaps = 1/109 (0%)
Frame = -1
Query: 567 KGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GSDDVTK 391
K LSD+E++ + FI AG++T L + + + +HP VQQ++ +E+ VL T
Sbjct: 288 KALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTY 347
Query: 390 QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
+ L YL+ + ET+RL+P+A + RV DV++ IP G V +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 48.8 bits (111), Expect = 2e-05
Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LHH P + ++ E F PER+ + + + F +G RNCIG FA+++MK L
Sbjct: 398 SYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALV 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 72.1 bits (169), Expect = 2e-12
Identities = 37/109 (33%), Positives = 61/109 (55%), Gaps = 1/109 (0%)
Frame = -1
Query: 567 KGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GSDDVTK 391
K LSD+E++ + FI AG++T L + + + +HP VQQ++ +E+ VL T
Sbjct: 288 KALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTY 347
Query: 390 QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
+ L YL+ + ET+RL+P+A + RV DV++ IP G V +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 48.8 bits (111), Expect = 2e-05
Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LHH P + ++ E F PER+ + + + F +G RNCIG FA+++MK L
Sbjct: 398 SYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALV 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 72.1 bits (169), Expect = 2e-12
Identities = 37/109 (33%), Positives = 61/109 (55%), Gaps = 1/109 (0%)
Frame = -1
Query: 567 KGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GSDDVTK 391
K LSD+E++ + FI AG++T L + + + +HP VQQ++ +E+ VL T
Sbjct: 288 KALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTY 347
Query: 390 QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
+ L YL+ + ET+RL+P+A + RV DV++ IP G V +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMI 396
Score = 48.8 bits (111), Expect = 2e-05
Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
Frame = -2
Query: 251 SLCLHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLA 78
S LHH P + ++ E F PER+ + + + F +G RNCIG FA+++MK L
Sbjct: 398 SYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALV 457
Query: 77 HLLRQY 60
+L+ +
Sbjct: 458 RVLQNF 463
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 71.7 bits (168), Expect = 2e-12
Identities = 38/114 (33%), Positives = 62/114 (54%), Gaps = 1/114 (0%)
Frame = -1
Query: 582 EIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL-GS 406
E K LSD+E+ + FI AG++T L +TL + +HP VQQ++ +E+ VL
Sbjct: 283 ETESHKALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNK 342
Query: 405 DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
T + + YL+ + ET+RL+P+A + R DV++ IP G+ V +
Sbjct: 343 APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCMKDVEINGVFIPKGSMVVI 396
Score = 54.0 bits (124), Expect = 5e-07
Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPT-TLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLR 66
LHH P + ++ E F+PER+ ++ + F TG RNCIG FA+M+MK L +L+
Sbjct: 401 LHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQ 460
Query: 65 QYRV-TADITRMEAKLD 18
+ T++ KLD
Sbjct: 461 NFSFKPCKETQIPLKLD 477
>BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family
27, subfamily C, polypeptide 1 protein.
Length = 372
Score = 70.9 bits (166), Expect = 4e-12
Identities = 37/109 (33%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Frame = -1
Query: 567 KGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDV-TK 391
+ L+ E+ + + AG DT +TL +T+ + HP VQQ +Y E+ + LG V T
Sbjct: 163 QALTLQEIYANVTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGERHVPTA 222
Query: 390 QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
++ + + A +KET+RL+P+ P RVT D+ + IP G +AL
Sbjct: 223 ADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLAL 271
Score = 33.9 bits (74), Expect = 0.52
Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Frame = -2
Query: 209 EHFKPERWLDPTTLPENAFAG---FSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV--TAD 45
+ F+PERWL L G F G R+CIG+ A + + + LL+ + + ++
Sbjct: 287 KEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSSQ 346
Query: 44 ITRMEAKLDIILKP 3
+ AK +L P
Sbjct: 347 TNAVHAKTHGLLTP 360
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 70.9 bits (166), Expect = 4e-12
Identities = 37/109 (33%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Frame = -1
Query: 567 KGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDV-TK 391
+ L+ E+ + + AG DT +TL +T+ + HP VQQ +Y E+ + LG V T
Sbjct: 163 QALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTA 222
Query: 390 QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
++ + + A +KET+RL+P+ P RVT D+ + IP G +AL
Sbjct: 223 ADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLAL 271
Score = 33.9 bits (74), Expect = 0.52
Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Frame = -2
Query: 209 EHFKPERWLDPTTLPENAFAG---FSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV--TAD 45
+ F+PERWL L G F G R+CIG+ A + + + LL+ + + ++
Sbjct: 287 KEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSSQ 346
Query: 44 ITRMEAKLDIILKP 3
+ AK +L P
Sbjct: 347 TNAVHAKTHGLLTP 360
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 70.5 bits (165), Expect = 5e-12
Identities = 38/124 (30%), Positives = 70/124 (56%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEE--KGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E K S+ ++ E+ TF+ AGHDT + + L C+ +P QQR +E
Sbjct: 284 FLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDE 343
Query: 426 LQQVLG-SDDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
++++LG +T ++LS + Y IKE +RLY +SR+ D + + ++P+G +
Sbjct: 344 IRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGIT 403
Query: 252 VALS 241
V ++
Sbjct: 404 VFIN 407
Score = 48.0 bits (109), Expect = 3e-05
Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH+P + D + F P R+ + + AF FS G RNCIG+ FA++ K +A L
Sbjct: 411 LHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTL 470
Query: 68 RQYRVTADITR 36
++++ D +R
Sbjct: 471 LRFKLAPDHSR 481
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 70.5 bits (165), Expect = 5e-12
Identities = 38/124 (30%), Positives = 70/124 (56%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEE--KGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E K S+ ++ E+ TF+ AGHDT + + L C+ +P QQR +E
Sbjct: 284 FLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDE 343
Query: 426 LQQVLG-SDDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
++++LG +T ++LS + Y IKE +RLY +SR+ D + + ++P+G +
Sbjct: 344 IRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGIT 403
Query: 252 VALS 241
V ++
Sbjct: 404 VFIN 407
Score = 48.0 bits (109), Expect = 3e-05
Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH+P + D + F P R+ + + AF FS G RNCIG+ FA++ K +A L
Sbjct: 411 LHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTL 470
Query: 68 RQYRVTADITR 36
++++ D +R
Sbjct: 471 LRFKLAPDHSR 481
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 70.5 bits (165), Expect = 5e-12
Identities = 38/124 (30%), Positives = 70/124 (56%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEE--KGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E K S+ ++ E+ TF+ AGHDT + + L C+ +P QQR +E
Sbjct: 284 FLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDE 343
Query: 426 LQQVLG-SDDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
++++LG +T ++LS + Y IKE +RLY +SR+ D + + ++P+G +
Sbjct: 344 IRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGIT 403
Query: 252 VALS 241
V ++
Sbjct: 404 VFIN 407
Score = 48.0 bits (109), Expect = 3e-05
Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH+P + D + F P R+ + + AF FS G RNCIG+ FA++ K +A L
Sbjct: 411 LHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTL 470
Query: 68 RQYRVTADITR 36
++++ D +R
Sbjct: 471 LRFKLAPDHSR 481
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 70.5 bits (165), Expect = 5e-12
Identities = 38/124 (30%), Positives = 70/124 (56%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEE--KGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E K S+ ++ E+ TF+ AGHDT + + L C+ +P QQR +E
Sbjct: 284 FLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDE 343
Query: 426 LQQVLG-SDDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
++++LG +T ++LS + Y IKE +RLY +SR+ D + + ++P+G +
Sbjct: 344 IRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGIT 403
Query: 252 VALS 241
V ++
Sbjct: 404 VFIN 407
Score = 48.0 bits (109), Expect = 3e-05
Identities = 25/71 (35%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWL--DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
LHH+P + D + F P R+ + + AF FS G RNCIG+ FA++ K +A L
Sbjct: 411 LHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTL 470
Query: 68 RQYRVTADITR 36
++++ D +R
Sbjct: 471 LRFKLAPDHSR 481
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 69.3 bits (162), Expect = 1e-11
Identities = 42/120 (35%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQE 357
Query: 426 LQQVLGSDD---VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L D + +L+ L +L +KE++RL+P AP +SR D+ L + IP G
Sbjct: 358 VQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKG 417
Score = 58.4 bits (135), Expect = 2e-08
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHL 72
+HH+P D E + P R+ DP AF FS G RNCIG+ FAM MK LA +
Sbjct: 427 VHHNPTVWPDPEVYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALM 485
Query: 71 LRQYRVTADITRMEAKLDIILK 6
L +R D T KL++I++
Sbjct: 486 LLHFRFLPDHTEPRRKLELIMR 507
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 69.3 bits (162), Expect = 1e-11
Identities = 42/120 (35%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQE 357
Query: 426 LQQVLGSDD---VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L D + +L+ L +L +KE++RL+P AP +SR D+ L + IP G
Sbjct: 358 VQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKG 417
Score = 58.4 bits (135), Expect = 2e-08
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHL 72
+HH+P D E + P R+ DP AF FS G RNCIG+ FAM MK LA +
Sbjct: 427 VHHNPTVWPDPEVYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALM 485
Query: 71 LRQYRVTADITRMEAKLDIILK 6
L +R D T KL++I++
Sbjct: 486 LLHFRFLPDHTEPRRKLELIMR 507
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 69.3 bits (162), Expect = 1e-11
Identities = 42/120 (35%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQE 357
Query: 426 LQQVLGSDD---VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L D + +L+ L +L +KE++RL+P AP +SR D+ L + IP G
Sbjct: 358 VQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKG 417
Score = 58.4 bits (135), Expect = 2e-08
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHL 72
+HH+P D E + P R+ DP AF FS G RNCIG+ FAM MK LA +
Sbjct: 427 VHHNPTVWPDPEVYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALM 485
Query: 71 LRQYRVTADITRMEAKLDIILK 6
L +R D T KL++I++
Sbjct: 486 LLHFRFLPDHTEPRRKLELIMR 507
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 69.3 bits (162), Expect = 1e-11
Identities = 42/120 (35%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 232 FIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQE 291
Query: 426 LQQVLGSDD---VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L D + +L+ L +L +KE++RL+P AP +SR D+ L + IP G
Sbjct: 292 VQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKG 351
Score = 58.4 bits (135), Expect = 2e-08
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHL 72
+HH+P D E + P R+ DP AF FS G RNCIG+ FAM MK LA +
Sbjct: 361 VHHNPTVWPDPEVYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALM 419
Query: 71 LRQYRVTADITRMEAKLDIILK 6
L +R D T KL++I++
Sbjct: 420 LLHFRFLPDHTEPRRKLELIMR 441
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 69.3 bits (162), Expect = 1e-11
Identities = 42/120 (35%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQE 357
Query: 426 LQQVLGSDD---VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L D + +L+ L +L +KE++RL+P AP +SR D+ L + IP G
Sbjct: 358 VQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKG 417
Score = 58.4 bits (135), Expect = 2e-08
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHL 72
+HH+P D E + P R+ DP AF FS G RNCIG+ FAM MK LA +
Sbjct: 427 VHHNPTVWPDPEVYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALM 485
Query: 71 LRQYRVTADITRMEAKLDIILK 6
L +R D T KL++I++
Sbjct: 486 LLHFRFLPDHTEPRRKLELIMR 507
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 69.3 bits (162), Expect = 1e-11
Identities = 42/120 (35%), Positives = 66/120 (55%), Gaps = 6/120 (5%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQE 357
Query: 426 LQQVLGSDD---VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L D + +L+ L +L +KE++RL+P AP +SR D+ L + IP G
Sbjct: 358 VQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKG 417
Score = 58.4 bits (135), Expect = 2e-08
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHL 72
+HH+P D E + P R+ DP AF FS G RNCIG+ FAM MK LA +
Sbjct: 427 VHHNPTVWPDPEVYDPFRF-DPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALM 485
Query: 71 LRQYRVTADITRMEAKLDIILK 6
L +R D T KL++I++
Sbjct: 486 LLHFRFLPDHTEPRRKLELIMR 507
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/70 (40%), Positives = 38/70 (54%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P + E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 418 LHHNPKVWPNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLR 477
Query: 62 YRVTADITRM 33
+ + D TR+
Sbjct: 478 FELLPDPTRI 487
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
Score = 54.8 bits (126), Expect = 3e-07
Identities = 28/70 (40%), Positives = 38/70 (54%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P + E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 418 LHHNPKVWPNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLR 477
Query: 62 YRVTADITRM 33
+ + D TR+
Sbjct: 478 FELLPDPTRI 487
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/70 (40%), Positives = 38/70 (54%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P + E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 418 LHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLR 477
Query: 62 YRVTADITRM 33
+ + D TR+
Sbjct: 478 FELLPDPTRI 487
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/70 (40%), Positives = 38/70 (54%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P + E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 418 LHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLR 477
Query: 62 YRVTADITRM 33
+ + D TR+
Sbjct: 478 FELLPDPTRI 487
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 292 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 351
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 352 IHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 411
Query: 252 VALS 241
V LS
Sbjct: 412 VLLS 415
Score = 48.0 bits (109), Expect = 3e-05
Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKT-TLAHLLR 66
LHH+P + E F P R+ + +AF FS G RNCIGK FAM +K A L
Sbjct: 419 LHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVGQQALTLV 478
Query: 65 QYRVTADITRM 33
++ + D TR+
Sbjct: 479 RFELLPDPTRI 489
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/70 (40%), Positives = 38/70 (54%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P + E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 418 LHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLR 477
Query: 62 YRVTADITRM 33
+ + D TR+
Sbjct: 478 FELLPDPTRI 487
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
Score = 52.8 bits (121), Expect = 1e-06
Identities = 28/69 (40%), Positives = 37/69 (53%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P + E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 418 LHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLR 477
Query: 62 YRVTADITR 36
+ + D TR
Sbjct: 478 FELLPDPTR 486
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 68.9 bits (161), Expect = 2e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/70 (40%), Positives = 38/70 (54%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P + E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 418 LHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLR 477
Query: 62 YRVTADITRM 33
+ + D TR+
Sbjct: 478 FELLPDPTRI 487
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 68.9 bits (161), Expect = 2e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 285 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCIALYPEHQHRCREE 344
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 345 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 404
Query: 252 VAL 244
+++
Sbjct: 405 ISM 407
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 442 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 285 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 344
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 345 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 404
Query: 252 VAL 244
+++
Sbjct: 405 ISM 407
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 442 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 68.1 bits (159), Expect = 3e-11
Identities = 40/135 (29%), Positives = 71/135 (52%), Gaps = 1/135 (0%)
Frame = -1
Query: 642 LENGTQDYSGEQKPFIDLXIEIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVG 463
++N + YS Q+P D +I + LS E+ + A +T +L++ L +
Sbjct: 29 IDNRLEKYS--QQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLS 86
Query: 462 SHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQQ++ +E+Q VL + V + ++L ++ YL+A +KE+MRL P P +R D
Sbjct: 87 RNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATV 146
Query: 285 LRNSTIPSGASVALS 241
L +P G + L+
Sbjct: 147 LGEYALPKGTVLMLN 161
Score = 41.9 bits (94), Expect = 0.002
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = -2
Query: 215 DVEHFKPERWL-DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTA 48
D F+PERWL + + A F GKR CIG+ A + + L ++R+Y + A
Sbjct: 174 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQA 230
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 285 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 344
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 345 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 404
Query: 252 VAL 244
+++
Sbjct: 405 ISM 407
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 442 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/126 (34%), Positives = 67/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L IKE++RL+P P VSR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 58.8 bits (136), Expect = 2e-08
Identities = 33/81 (40%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+ FAM MK L L
Sbjct: 428 HHNPAVWPDPEVYDPFRF-DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
+RV D T K +++L+
Sbjct: 487 LAFRVLPDHTEPRRKPELVLR 507
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 285 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 344
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 345 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 404
Query: 252 VAL 244
+++
Sbjct: 405 ISM 407
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 442 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487
>BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein.
Length = 455
Score = 68.1 bits (159), Expect = 3e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 286 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 345
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 346 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 405
Query: 252 VAL 244
+++
Sbjct: 406 ISM 408
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 443 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 488
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 68.1 bits (159), Expect = 3e-11
Identities = 40/135 (29%), Positives = 71/135 (52%), Gaps = 1/135 (0%)
Frame = -1
Query: 642 LENGTQDYSGEQKPFIDLXIEIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVG 463
++N + YS Q+P D +I + LS E+ + A +T +L++ L +
Sbjct: 144 IDNRLEKYS--QQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLS 201
Query: 462 SHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQQ++ +E+Q VL + V + ++L ++ YL+A +KE+MRL P P +R D
Sbjct: 202 RNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATV 261
Query: 285 LRNSTIPSGASVALS 241
L +P G + L+
Sbjct: 262 LGEYALPKGTVLMLN 276
Score = 41.9 bits (94), Expect = 0.002
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = -2
Query: 215 DVEHFKPERWL-DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTA 48
D F+PERWL + + A F GKR CIG+ A + + L ++R+Y + A
Sbjct: 289 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQA 345
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/126 (34%), Positives = 67/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L IKE++RL+P P VSR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 59.7 bits (138), Expect = 9e-09
Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+ FAM MK L L
Sbjct: 428 HHNPAVWPDPEVYDPFRF-DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
++RV D T K +++L+
Sbjct: 487 LRFRVLPDHTEPRRKPELVLR 507
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 68.1 bits (159), Expect = 3e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
Score = 54.4 bits (125), Expect = 3e-07
Identities = 28/70 (40%), Positives = 38/70 (54%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P + E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 418 LHHNPKVWPNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLR 477
Query: 62 YRVTADITRM 33
+ + D TR+
Sbjct: 478 FELLPDPTRI 487
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 271 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 330
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 331 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 390
Query: 252 VAL 244
+++
Sbjct: 391 ISM 393
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 428 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 473
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 286 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 345
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 346 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 405
Query: 252 VAL 244
+++
Sbjct: 406 ISM 408
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 443 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 488
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 285 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 344
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 345 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 404
Query: 252 VAL 244
+++
Sbjct: 405 ISM 407
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 442 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 286 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 345
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 346 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 405
Query: 252 VAL 244
+++
Sbjct: 406 ISM 408
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 443 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 488
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 285 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 344
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 345 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 404
Query: 252 VAL 244
+++
Sbjct: 405 ISM 407
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 442 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 271 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 330
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 331 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 390
Query: 252 VAL 244
+++
Sbjct: 391 ISM 393
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 428 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 473
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 286 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 345
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 346 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 405
Query: 252 VAL 244
+++
Sbjct: 406 ISM 408
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 443 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 488
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 285 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 344
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 345 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 404
Query: 252 VAL 244
+++
Sbjct: 405 ISM 407
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 442 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 271 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREE 330
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 331 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 390
Query: 252 VAL 244
+++
Sbjct: 391 ISM 393
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 428 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 473
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 68.1 bits (159), Expect = 3e-11
Identities = 40/135 (29%), Positives = 71/135 (52%), Gaps = 1/135 (0%)
Frame = -1
Query: 642 LENGTQDYSGEQKPFIDLXIEIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVG 463
++N + YS Q+P D +I + LS E+ + A +T +L++ L +
Sbjct: 286 IDNRLEKYS--QQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLS 343
Query: 462 SHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQQ++ +E+Q VL + V + ++L ++ YL+A +KE+MRL P P +R D
Sbjct: 344 RNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATV 403
Query: 285 LRNSTIPSGASVALS 241
L +P G + L+
Sbjct: 404 LGEYALPKGTVLMLN 418
Score = 41.9 bits (94), Expect = 0.002
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = -2
Query: 215 DVEHFKPERWL-DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTA 48
D F+PERWL + + A F GKR CIG+ A + + L ++R+Y + A
Sbjct: 431 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQA 487
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 68.1 bits (159), Expect = 3e-11
Identities = 40/135 (29%), Positives = 71/135 (52%), Gaps = 1/135 (0%)
Frame = -1
Query: 642 LENGTQDYSGEQKPFIDLXIEIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVG 463
++N + YS Q+P D +I + LS E+ + A +T +L++ L +
Sbjct: 144 IDNRLEKYS--QQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLS 201
Query: 462 SHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQQ++ +E+Q VL + V + ++L ++ YL+A +KE+MRL P P +R D
Sbjct: 202 RNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATV 261
Query: 285 LRNSTIPSGASVALS 241
L +P G + L+
Sbjct: 262 LGEYALPKGTVLMLN 276
Score = 41.9 bits (94), Expect = 0.002
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = -2
Query: 215 DVEHFKPERWL-DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTA 48
D F+PERWL + + A F GKR CIG+ A + + L ++R+Y + A
Sbjct: 289 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQA 345
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 68.1 bits (159), Expect = 3e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 68.1 bits (159), Expect = 3e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/70 (40%), Positives = 39/70 (55%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P ++E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 418 LHHNPKVWPNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLR 477
Query: 62 YRVTADITRM 33
+ + D TR+
Sbjct: 478 FELLPDPTRI 487
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 68.1 bits (159), Expect = 3e-11
Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RLYP P + R V + ++P G
Sbjct: 351 IHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/70 (40%), Positives = 39/70 (55%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P ++E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 418 LHHNPKVWPNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLR 477
Query: 62 YRVTADITRM 33
+ + D TR+
Sbjct: 478 FELLPDPTRI 487
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/126 (34%), Positives = 67/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L IKE++RL+P P VSR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 59.7 bits (138), Expect = 9e-09
Identities = 33/81 (40%), Positives = 44/81 (54%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+ FAM MK L L
Sbjct: 428 HHNPAVWPDPEVYDPFRF-DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
++RV D T K +++L+
Sbjct: 487 LRFRVLPDHTEPRRKPELVLR 507
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/126 (34%), Positives = 67/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L IKE++RL+P P VSR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 58.8 bits (136), Expect = 2e-08
Identities = 33/81 (40%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+ FAM MK L L
Sbjct: 428 HHNPAVWPDPEVYDPFRF-DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
+RV D T K +++L+
Sbjct: 487 LAFRVLPDHTEPRRKPELVLR 507
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/126 (34%), Positives = 67/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L IKE++RL+P P VSR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 58.8 bits (136), Expect = 2e-08
Identities = 33/81 (40%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+ FAM MK L L
Sbjct: 428 HHNPAVWPDPEVYDPFRF-DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
+RV D T K +++L+
Sbjct: 487 LAFRVLPDHTEPRRKPELVLR 507
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 67.7 bits (158), Expect = 3e-11
Identities = 39/123 (31%), Positives = 67/123 (54%), Gaps = 4/123 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + +E LSD ++ E+ TF+ GHDT + + L C+ +P Q R EE
Sbjct: 285 FLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTGGISWFLYCMALYPEHQHRCREE 344
Query: 426 LQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK-LRNSTIPSGAS 253
++++LG D + +L + YL IKE+ RLYP P V R V + ++P+G+
Sbjct: 345 VREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSL 404
Query: 252 VAL 244
+++
Sbjct: 405 ISM 407
Score = 43.2 bits (97), Expect = 9e-04
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -2
Query: 158 AFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRMEAKL 21
AF FS G RNCIG+ FAM MK A L ++ + D +R+ K+
Sbjct: 442 AFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM 487
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 67.3 bits (157), Expect = 5e-11
Identities = 42/126 (33%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L +KE++RL+P PV+SR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 63.3 bits (147), Expect = 7e-10
Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+TFAM MK LA L
Sbjct: 428 HHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
++RV D T K +++L+
Sbjct: 487 LRFRVLPDHTEPRRKPELVLR 507
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 67.3 bits (157), Expect = 5e-11
Identities = 42/126 (33%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L +KE++RL+P PV+SR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 64.1 bits (149), Expect = 4e-10
Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+TFAM MK LA L
Sbjct: 428 HHNPAMWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
++RV D T K +++L+
Sbjct: 487 LRFRVLPDHTEPRRKPELVLR 507
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 67.3 bits (157), Expect = 5e-11
Identities = 42/126 (33%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L +KE++RL+P PV+SR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 63.3 bits (147), Expect = 7e-10
Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+TFAM MK LA L
Sbjct: 428 HHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
++RV D T K +++L+
Sbjct: 487 LRFRVLPDHTEPRRKPELVLR 507
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 67.3 bits (157), Expect = 5e-11
Identities = 42/126 (33%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L +KE++RL+P PV+SR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 63.3 bits (147), Expect = 7e-10
Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+TFAM MK LA L
Sbjct: 428 HHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
++RV D T K +++L+
Sbjct: 487 LRFRVLPDHTEPRRKPELVLR 507
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 67.3 bits (157), Expect = 5e-11
Identities = 40/124 (32%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
F+D+ + E G LSD ++ E+ TF+ GHDT + + L + +HP Q+R EE
Sbjct: 291 FLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREE 350
Query: 426 LQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGAS 253
+ +LG +T +L + Y IKE +RL+P P + R V + ++P G
Sbjct: 351 IHSLLGDGASITWNHLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTFPDGRSLPKGIM 410
Query: 252 VALS 241
V LS
Sbjct: 411 VLLS 414
Score = 53.6 bits (123), Expect = 6e-07
Identities = 28/70 (40%), Positives = 38/70 (54%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P + E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 418 LHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLR 477
Query: 62 YRVTADITRM 33
+ + D TR+
Sbjct: 478 FELLPDPTRI 487
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 67.3 bits (157), Expect = 5e-11
Identities = 42/126 (33%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L +KE++RL+P PV+SR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 63.3 bits (147), Expect = 7e-10
Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+TFAM MK LA L
Sbjct: 428 HHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
++RV D T K +++L+
Sbjct: 487 LRFRVLPDHTEPRRKPELVLR 507
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 67.3 bits (157), Expect = 5e-11
Identities = 42/126 (33%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L +KE++RL+P PV+SR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 63.3 bits (147), Expect = 7e-10
Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+TFAM MK LA L
Sbjct: 428 HHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
++RV D T K +++L+
Sbjct: 487 LRFRVLPDHTEPRRKPELVLR 507
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 67.3 bits (157), Expect = 5e-11
Identities = 42/126 (33%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L +KE++RL+P PV+SR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 64.1 bits (149), Expect = 4e-10
Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+TFAM MK LA L
Sbjct: 428 HHNPAMWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
++RV D T K +++L+
Sbjct: 487 LRFRVLPDHTEPRRKPELVLR 507
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 66.9 bits (156), Expect = 6e-11
Identities = 41/126 (32%), Positives = 68/126 (53%), Gaps = 6/126 (4%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASVLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L +KE++R++P PV+SR D+ L + IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRVHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 258 ASVALS 241
+S
Sbjct: 418 IICLIS 423
Score = 63.3 bits (147), Expect = 7e-10
Identities = 35/81 (43%), Positives = 46/81 (56%), Gaps = 3/81 (3%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D E + P R+ DP + E AF FS G RNCIG+TFAM MK LA L
Sbjct: 428 HHNPAVWPDPEVYDPFRF-DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
++RV D T K +++L+
Sbjct: 487 LRFRVLPDHTEPRRKPELVLR 507
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 66.9 bits (156), Expect = 6e-11
Identities = 39/129 (30%), Positives = 68/129 (52%), Gaps = 1/129 (0%)
Frame = -1
Query: 642 LENGTQDYSGEQKPFIDLXIEIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVG 463
++N + YS Q+P D +I + LS E+ + A +T +L++ L +
Sbjct: 286 IDNRLEKYS--QQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLS 343
Query: 462 SHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQQ++ +E+Q VL + V + ++L ++ YL+A +KE+MRL P P +R D
Sbjct: 344 RNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATV 403
Query: 285 LRNSTIPSG 259
L +P G
Sbjct: 404 LGEYALPKG 412
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 66.9 bits (156), Expect = 6e-11
Identities = 39/129 (30%), Positives = 68/129 (52%), Gaps = 1/129 (0%)
Frame = -1
Query: 642 LENGTQDYSGEQKPFIDLXIEIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVG 463
++N + YS Q+P D +I + LS E+ + A +T +L++ L +
Sbjct: 286 IDNRLEKYS--QQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLS 343
Query: 462 SHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQQ++ +E+Q VL + V + ++L ++ YL+A +KE+MRL P P +R D
Sbjct: 344 RNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATV 403
Query: 285 LRNSTIPSG 259
L +P G
Sbjct: 404 LGEYALPKG 412
>AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 66.9 bits (156), Expect = 6e-11
Identities = 39/129 (30%), Positives = 68/129 (52%), Gaps = 1/129 (0%)
Frame = -1
Query: 642 LENGTQDYSGEQKPFIDLXIEIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVG 463
++N + YS Q+P D +I + LS E+ + A +T +L++ L +
Sbjct: 286 IDNRLEKYS--QQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLS 343
Query: 462 SHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQQ++ +E+Q VL + V + ++L ++ YL+A +KE+MRL P P +R D
Sbjct: 344 RNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATV 403
Query: 285 LRNSTIPSG 259
L +P G
Sbjct: 404 LGEYALPKG 412
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 65.3 bits (152), Expect = 2e-10
Identities = 41/120 (34%), Positives = 65/120 (54%), Gaps = 6/120 (5%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q++ +E
Sbjct: 298 FIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQE 357
Query: 426 LQQVLGSD---DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L IKE++RL+P PV+SR D L + IP G
Sbjct: 358 VQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKG 417
Score = 51.6 bits (118), Expect = 2e-06
Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPEN--AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
+H++P D E + P R+ + AF FS G RNCIG+ FAM MK LA L
Sbjct: 427 IHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
+R+ T K ++IL+
Sbjct: 487 LHFRILPTHTEPRRKPELILR 507
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 65.3 bits (152), Expect = 2e-10
Identities = 41/120 (34%), Positives = 65/120 (54%), Gaps = 6/120 (5%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q++ +E
Sbjct: 298 FIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQE 357
Query: 426 LQQVLGSD---DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L IKE++RL+P PV+SR D L + IP G
Sbjct: 358 VQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKG 417
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPEN--AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
+H++P D E + P R+ + AF FS G RNCIG+ FAM MK LA L
Sbjct: 427 IHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTL 486
Query: 68 RQYRVTADITRMEAKLDIILK 6
+R+ K ++IL+
Sbjct: 487 LHFRILPTHIEPRRKPELILR 507
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 64.5 bits (150), Expect = 3e-10
Identities = 39/135 (28%), Positives = 70/135 (51%), Gaps = 1/135 (0%)
Frame = -1
Query: 642 LENGTQDYSGEQKPFIDLXIEIAEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVG 463
++N + YS Q+P D +I + LS E+ + A +T +L++ L +
Sbjct: 285 IDNRLEKYS--QQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLS 342
Query: 462 SHPPVQQRIYEELQQVLGSDD-VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVK 286
+P VQQ++ +E+Q VL + +++L ++ YL+A +KE+MRL P P +R D
Sbjct: 343 RNPQVQQKLLKEIQSVLPENQRPREEDLRNMPYLKACLKESMRLTPGVPFTTRTLDKATV 402
Query: 285 LRNSTIPSGASVALS 241
L +P G + L+
Sbjct: 403 LGEYALPKGTVLMLN 417
Score = 41.9 bits (94), Expect = 0.002
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Frame = -2
Query: 215 DVEHFKPERWL-DPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTA 48
D F+PERWL + + A F GKR CIG+ A + + L ++R+Y + A
Sbjct: 430 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQA 486
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 63.7 bits (148), Expect = 6e-10
Identities = 40/125 (32%), Positives = 67/125 (53%), Gaps = 6/125 (4%)
Frame = -1
Query: 615 GEQKPFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQ 442
G+ FID+ + +E G LSD ++ E TF+ GHDT + + L + +P Q+
Sbjct: 300 GKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQE 359
Query: 441 RIYEELQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS- 274
+ EE+Q+V+ +++ +L+ L + IKE++R YP +VSR D+KL +
Sbjct: 360 KCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGR 419
Query: 273 TIPSG 259
IP G
Sbjct: 420 IIPKG 424
Score = 52.4 bits (120), Expect = 1e-06
Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 4/82 (4%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D + + P R+ DP + A+ FS G RNCIG++FAM ++ +A L
Sbjct: 435 HHNPTVWPDSKVYNPYRF-DPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTL 493
Query: 68 RQYRVTADITR-MEAKLDIILK 6
++R++ D TR + K ++IL+
Sbjct: 494 LRFRLSVDRTRKVRRKPELILR 515
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 63.7 bits (148), Expect = 6e-10
Identities = 40/125 (32%), Positives = 67/125 (53%), Gaps = 6/125 (4%)
Frame = -1
Query: 615 GEQKPFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQ 442
G+ FID+ + +E G LSD ++ E TF+ GHDT + + L + +P Q+
Sbjct: 300 GKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQE 359
Query: 441 RIYEELQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS- 274
+ EE+Q+V+ +++ +L+ L + IKE++R YP +VSR D+KL +
Sbjct: 360 KCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGR 419
Query: 273 TIPSG 259
IP G
Sbjct: 420 IIPKG 424
Score = 52.4 bits (120), Expect = 1e-06
Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 4/82 (4%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D + + P R+ DP + A+ FS G RNCIG++FAM ++ +A L
Sbjct: 435 HHNPTVWPDSKVYNPYRF-DPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTL 493
Query: 68 RQYRVTADITR-MEAKLDIILK 6
++R++ D TR + K ++IL+
Sbjct: 494 LRFRLSVDRTRKVRRKPELILR 515
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 63.7 bits (148), Expect = 6e-10
Identities = 40/125 (32%), Positives = 67/125 (53%), Gaps = 6/125 (4%)
Frame = -1
Query: 615 GEQKPFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQ 442
G+ FID+ + +E G LSD ++ E TF+ GHDT + + L + +P Q+
Sbjct: 300 GKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQE 359
Query: 441 RIYEELQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS- 274
+ EE+Q+V+ +++ +L+ L + IKE++R YP +VSR D+KL +
Sbjct: 360 KCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGR 419
Query: 273 TIPSG 259
IP G
Sbjct: 420 IIPKG 424
Score = 52.4 bits (120), Expect = 1e-06
Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 4/82 (4%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D + + P R+ DP + A+ FS G RNCIG++FAM ++ +A L
Sbjct: 435 HHNPTVWPDSKVYNPYRF-DPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTL 493
Query: 68 RQYRVTADITR-MEAKLDIILK 6
++R++ D TR + K ++IL+
Sbjct: 494 LRFRLSVDRTRKVRRKPELILR 515
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 63.7 bits (148), Expect = 6e-10
Identities = 40/125 (32%), Positives = 67/125 (53%), Gaps = 6/125 (4%)
Frame = -1
Query: 615 GEQKPFIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQ 442
G+ FID+ + +E G LSD ++ E TF+ GHDT + + L + +P Q+
Sbjct: 300 GKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQE 359
Query: 441 RIYEELQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS- 274
+ EE+Q+V+ +++ +L+ L + IKE++R YP +VSR D+KL +
Sbjct: 360 KCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPDGR 419
Query: 273 TIPSG 259
IP G
Sbjct: 420 IIPKG 424
Score = 52.4 bits (120), Expect = 1e-06
Identities = 29/82 (35%), Positives = 48/82 (58%), Gaps = 4/82 (4%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
HH+P D + + P R+ DP + A+ FS G RNCIG++FAM ++ +A L
Sbjct: 435 HHNPTVWPDSKVYNPYRF-DPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTL 493
Query: 68 RQYRVTADITR-MEAKLDIILK 6
++R++ D TR + K ++IL+
Sbjct: 494 LRFRLSVDRTRKVRRKPELILR 515
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 63.3 bits (147), Expect = 7e-10
Identities = 40/120 (33%), Positives = 65/120 (54%), Gaps = 6/120 (5%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + ++ G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNS-TIPSG 259
+Q++L ++ +L+ L +L +KE++RL+P P +R DV L +S IP G
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKG 417
Score = 53.6 bits (123), Expect = 6e-07
Identities = 31/82 (37%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPEN---AFAGFSTGKRNCIGKTFAMMSMKTTLAHL 72
+HH+P D E + P R+ DP + AF FS G RNCIG+ FAM MK LA
Sbjct: 427 IHHNPSVWPDPEVYDPFRF-DPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALT 485
Query: 71 LRQYRVTADITRMEAKLDIILK 6
L ++R+ D +I+L+
Sbjct: 486 LLRFRILPDHREPRRTPEIVLR 507
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL--GSDDVTKQ 388
L ++ + + AG DTV TL + L + HP VQ ++ E+ L GS
Sbjct: 302 LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSA 361
Query: 387 N-LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
LS L L+A +KE +RLYP+ P SRV D D+ + + IP V L
Sbjct: 362 TVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTL 410
Score = 38.7 bits (86), Expect = 0.018
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)
Frame = -2
Query: 254 VSLCLH---HHPVWGSDVEHFKPERWLDPTTLPEN-AFAGFSTGKRNCIGKTFAMMSMKT 87
V+LC + P + F+P RWL P A F GKR+C+G+ A + ++
Sbjct: 408 VTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQM 467
Query: 86 TLAHLLRQYRV 54
LA +L + V
Sbjct: 468 ALAQILTHFEV 478
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL--GSDDVTKQ 388
L ++ + + AG DTV TL + L + HP VQ ++ E+ L GS
Sbjct: 302 LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSA 361
Query: 387 N-LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
LS L L+A +KE +RLYP+ P SRV D D+ + + IP V L
Sbjct: 362 TVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTL 410
Score = 38.7 bits (86), Expect = 0.018
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)
Frame = -2
Query: 254 VSLCLH---HHPVWGSDVEHFKPERWLDPTTLPEN-AFAGFSTGKRNCIGKTFAMMSMKT 87
V+LC + P + F+P RWL P A F GKR+C+G+ A + ++
Sbjct: 408 VTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQM 467
Query: 86 TLAHLLRQYRV 54
LA +L + V
Sbjct: 468 ALAQILTHFEV 478
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL--GSDDVTKQ 388
L ++ + + AG DTV TL + L + HP VQ ++ E+ L GS
Sbjct: 302 LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSA 361
Query: 387 N-LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
LS L L+A +KE +RLYP+ P SRV D D+ + + IP V L
Sbjct: 362 TVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTL 410
Score = 38.7 bits (86), Expect = 0.018
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)
Frame = -2
Query: 254 VSLCLH---HHPVWGSDVEHFKPERWLDPTTLPEN-AFAGFSTGKRNCIGKTFAMMSMKT 87
V+LC + P + F+P RWL P A F GKR+C+G+ A + ++
Sbjct: 408 VTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQM 467
Query: 86 TLAHLLRQYRV 54
LA +L + V
Sbjct: 468 ALAQILTHFEV 478
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL--GSDDVTKQ 388
L ++ + + AG DTV TL + L + HP VQ ++ E+ L GS
Sbjct: 302 LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSA 361
Query: 387 N-LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
LS L L+A +KE +RLYP+ P SRV D D+ + + IP V L
Sbjct: 362 TVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTL 410
Score = 38.7 bits (86), Expect = 0.018
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)
Frame = -2
Query: 254 VSLCLH---HHPVWGSDVEHFKPERWLDPTTLPEN-AFAGFSTGKRNCIGKTFAMMSMKT 87
V+LC + P + F+P RWL P A F GKR+C+G+ A + ++
Sbjct: 408 VTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQM 467
Query: 86 TLAHLLRQYRV 54
LA +L + V
Sbjct: 468 ALAQILTHFEV 478
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL--GSDDVTKQ 388
L ++ + + AG DTV TL + L + HP VQ ++ E+ L GS
Sbjct: 302 LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSA 361
Query: 387 N-LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
LS L L+A +KE +RLYP+ P SRV D D+ + + IP V L
Sbjct: 362 TVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTL 410
Score = 38.7 bits (86), Expect = 0.018
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)
Frame = -2
Query: 254 VSLCLH---HHPVWGSDVEHFKPERWLDPTTLPEN-AFAGFSTGKRNCIGKTFAMMSMKT 87
V+LC + P + F+P RWL P A F GKR+C+G+ A + ++
Sbjct: 408 VTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQM 467
Query: 86 TLAHLLRQYRV 54
LA +L + V
Sbjct: 468 ALAQILTHFEV 478
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL--GSDDVTKQ 388
L ++ + + AG DTV TL + L + HP VQ ++ E+ L GS
Sbjct: 302 LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSA 361
Query: 387 N-LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
LS L L+A +KE +RLYP+ P SRV D D+ + + IP V L
Sbjct: 362 TVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTL 410
Score = 38.7 bits (86), Expect = 0.018
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)
Frame = -2
Query: 254 VSLCLH---HHPVWGSDVEHFKPERWLDPTTLPEN-AFAGFSTGKRNCIGKTFAMMSMKT 87
V+LC + P + F+P RWL P A F GKR+C+G+ A + ++
Sbjct: 408 VTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQM 467
Query: 86 TLAHLLRQYRV 54
LA +L + V
Sbjct: 468 ALAQILTHFEV 478
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL--GSDDVTKQ 388
L ++ + + AG DTV TL + L + HP VQ ++ E+ L GS
Sbjct: 302 LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSA 361
Query: 387 N-LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
LS L L+A +KE +RLYP+ P SRV D D+ + + IP V L
Sbjct: 362 TVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTL 410
Score = 38.7 bits (86), Expect = 0.018
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)
Frame = -2
Query: 254 VSLCLH---HHPVWGSDVEHFKPERWLDPTTLPEN-AFAGFSTGKRNCIGKTFAMMSMKT 87
V+LC + P + F+P RWL P A F GKR+C+G+ A + ++
Sbjct: 408 VTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQM 467
Query: 86 TLAHLLRQYRV 54
LA +L + V
Sbjct: 468 ALAQILTHFEV 478
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL--GSDDVTKQ 388
L ++ + + AG DTV TL + L + HP VQ ++ E+ L GS
Sbjct: 302 LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSA 361
Query: 387 N-LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
LS L L+A +KE +RLYP+ P SRV D D+ + + IP V L
Sbjct: 362 TVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTL 410
Score = 38.7 bits (86), Expect = 0.018
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)
Frame = -2
Query: 254 VSLCLH---HHPVWGSDVEHFKPERWLDPTTLPEN-AFAGFSTGKRNCIGKTFAMMSMKT 87
V+LC + P + F+P RWL P A F GKR+C+G+ A + ++
Sbjct: 408 VTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQM 467
Query: 86 TLAHLLRQYRV 54
LA +L + V
Sbjct: 468 ALAQILTHFEV 478
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 3/109 (2%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVL--GSDDVTKQ 388
L ++ + + AG DTV TL + L + HP VQ ++ E+ L GS
Sbjct: 302 LPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSA 361
Query: 387 N-LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
LS L L+A +KE +RLYP+ P SRV D D+ + + IP V L
Sbjct: 362 TVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTL 410
Score = 38.7 bits (86), Expect = 0.018
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 4/71 (5%)
Frame = -2
Query: 254 VSLCLH---HHPVWGSDVEHFKPERWLDPTTLPEN-AFAGFSTGKRNCIGKTFAMMSMKT 87
V+LC + P + F+P RWL P A F GKR+C+G+ A + ++
Sbjct: 408 VTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQM 467
Query: 86 TLAHLLRQYRV 54
LA +L + V
Sbjct: 468 ALAQILTHFEV 478
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 61.3 bits (142), Expect = 3e-09
Identities = 34/98 (34%), Positives = 51/98 (52%), Gaps = 2/98 (2%)
Frame = -1
Query: 528 TFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEATI 352
TF+ GHDT + + L + +HP Q+R EE+ +LG +T +L + Y I
Sbjct: 1 TFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWNHLDQMPYTTMCI 60
Query: 351 KETMRLYPIAPVVSRVTDCDVKLRNS-TIPSGASVALS 241
KE +RLYP P +SR V + ++P G +V LS
Sbjct: 61 KEALRLYPPVPGISRELSTPVTFPDGRSLPKGITVMLS 98
Score = 33.9 bits (74), Expect = 0.52
Identities = 16/40 (40%), Positives = 21/40 (52%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNC 123
LHH+P + E F P R+ + +AF FS G RNC
Sbjct: 102 LHHNPKVWPNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNC 141
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 61.3 bits (142), Expect = 3e-09
Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 8/130 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDMEVIHE--LAT---FIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E E +AT AG +T TL Y L+ + HP V
Sbjct: 141 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYALLLLLKHPEVT 200
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE+++V+G + Q+ S + Y +A + E R + P + CDVK RN
Sbjct: 201 AKVQEEIERVVGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYL 260
Query: 270 IPSGASVALS 241
IP G ++ S
Sbjct: 261 IPKGTTILTS 270
Score = 33.1 bits (72), Expect = 0.92
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD N F FS GKR C+G+ A M + L +L+ + +
Sbjct: 285 EMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 338
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETM 340
AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ S + Y +A + E
Sbjct: 284 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQ 343
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
R + P + CD+K RN IP G ++ +S
Sbjct: 344 RYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILIS 377
Score = 30.7 bits (66), Expect = 4.9
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD F FS GKR C+G+ A M + L +L+ + +
Sbjct: 392 EMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNL 445
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETM 340
AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ S + Y +A + E
Sbjct: 190 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQ 249
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
R + P + CD+K RN IP G ++ +S
Sbjct: 250 RCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILIS 283
Score = 30.7 bits (66), Expect = 4.9
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD F FS GKR C+G+ A M + L +L+ + +
Sbjct: 298 EMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNL 351
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETM 340
AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ S + Y +A + E
Sbjct: 292 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQ 351
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
R + P + CD+K RN IP G ++ +S
Sbjct: 352 RCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILIS 385
Score = 30.7 bits (66), Expect = 4.9
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD F FS GKR C+G+ A M + L +L+ + +
Sbjct: 400 EMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNL 453
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETM 340
AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ S + Y +A + E
Sbjct: 292 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQ 351
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
R + P + CD+K RN IP G ++ +S
Sbjct: 352 RCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILIS 385
Score = 30.7 bits (66), Expect = 4.9
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD F FS GKR C+G+ A M + L +L+ + +
Sbjct: 400 EMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNL 453
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETM 340
AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ S + Y +A + E
Sbjct: 294 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQ 353
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
R + P + CD+K RN IP G ++ +S
Sbjct: 354 RYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILIS 387
Score = 30.7 bits (66), Expect = 4.9
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD F FS GKR C+G+ A M + L +L+ + +
Sbjct: 402 EMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNL 455
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETM 340
AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ S + Y +A + E
Sbjct: 297 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQ 356
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
R + P + CD+K RN IP G ++ +S
Sbjct: 357 RYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILIS 390
Score = 30.7 bits (66), Expect = 4.9
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD F FS GKR C+G+ A M + L +L+ + +
Sbjct: 405 EMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNL 458
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETM 340
AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ S + Y +A + E
Sbjct: 297 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQ 356
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
R + P + CD+K RN IP G ++ +S
Sbjct: 357 RYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILIS 390
Score = 30.7 bits (66), Expect = 4.9
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD F FS GKR C+G+ A M + L +L+ + +
Sbjct: 405 EMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNL 458
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETM 340
AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ S + Y +A + E
Sbjct: 297 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQ 356
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
R + P + CD+K RN IP G ++ +S
Sbjct: 357 RYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILIS 390
Score = 30.7 bits (66), Expect = 4.9
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD F FS GKR C+G+ A M + L +L+ + +
Sbjct: 405 EMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNL 458
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/94 (31%), Positives = 50/94 (53%), Gaps = 2/94 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETM 340
AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ S + Y +A + E
Sbjct: 297 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQ 356
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
R + P + CD+K RN IP G ++ +S
Sbjct: 357 RYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILIS 390
Score = 30.7 bits (66), Expect = 4.9
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD F FS GKR C+G+ A M + L +L+ + +
Sbjct: 405 EMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNL 458
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 60.5 bits (140), Expect = 5e-09
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Frame = -1
Query: 531 ATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEAT 355
A + AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ + Y +A
Sbjct: 292 ADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRGHMPYTDAV 351
Query: 354 IKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
+ E R + P + CDVK RN IP G ++ S
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTS 390
Score = 33.1 bits (72), Expect = 0.92
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD N F FS GKR C+G+ A M + L +L+ + +
Sbjct: 405 EMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
>L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 217
Score = 60.5 bits (140), Expect = 5e-09
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Frame = -1
Query: 531 ATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEAT 355
A + AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ + Y +A
Sbjct: 19 ADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRGHMPYTDAV 78
Query: 354 IKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
+ E R + P + CDVK RN IP G ++ S
Sbjct: 79 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTS 117
Score = 33.1 bits (72), Expect = 0.92
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD N F FS GKR C+G+ A M + L +L+ + +
Sbjct: 132 EMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 185
>X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C
protein.
Length = 356
Score = 60.1 bits (139), Expect = 7e-09
Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 8/130 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDMEVIHE-----LATFIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E E A + AG +T TL Y L+ + HP V
Sbjct: 127 RDFIDCFLIKMEQEKDNQKSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVT 186
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE+++V+G + Q+ + Y +A + E R + P + CD+K RN
Sbjct: 187 AKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDIKFRNYL 246
Query: 270 IPSGASVALS 241
IP G ++ S
Sbjct: 247 IPKGTTILTS 256
Score = 33.1 bits (72), Expect = 0.92
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD N F FS GKR C+G+ A M + L +L+ + +
Sbjct: 271 EMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 324
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 60.1 bits (139), Expect = 7e-09
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Frame = -1
Query: 531 ATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEAT 355
A + AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ + Y +A
Sbjct: 270 ADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAV 329
Query: 354 IKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
+ E R + P + CDVK RN IP G ++ S
Sbjct: 330 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTS 368
Score = 33.1 bits (72), Expect = 0.92
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD N F FS GKR C+G+ A M + L +L+ + +
Sbjct: 383 EMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 436
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 60.1 bits (139), Expect = 7e-09
Identities = 38/128 (29%), Positives = 64/128 (50%), Gaps = 3/128 (2%)
Frame = -1
Query: 615 GEQKPFIDLXIEI--AEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQ 442
GE+ P D+ +I AEE D ++ TF AGH+T L +T+M + P +
Sbjct: 268 GEEVP-ADILTQILKAEEGAQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVA 326
Query: 441 RIYEELQQVLGSDD-VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIP 265
R+ E+ +V+GS + ++L L YL +KE++RLYP A R+ + + + +P
Sbjct: 327 RLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVP 386
Query: 264 SGASVALS 241
+ S
Sbjct: 387 GNTPLLFS 394
Score = 39.9 bits (89), Expect = 0.008
Identities = 18/47 (38%), Positives = 27/47 (57%)
Frame = -2
Query: 203 FKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
F P+R+ P + FS G R+CIG+ FA M +K +A LL++
Sbjct: 411 FNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQR 457
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 60.1 bits (139), Expect = 7e-09
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Frame = -1
Query: 531 ATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEAT 355
A + AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ + Y +A
Sbjct: 292 ADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAV 351
Query: 354 IKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
+ E R + P + CDVK RN IP G ++ S
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTS 390
Score = 33.1 bits (72), Expect = 0.92
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD N F FS GKR C+G+ A M + L +L+ + +
Sbjct: 405 EMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 60.1 bits (139), Expect = 7e-09
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Frame = -1
Query: 531 ATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEAT 355
A + AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ + Y +A
Sbjct: 292 ADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAV 351
Query: 354 IKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
+ E R + P + CDVK RN IP G ++ S
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTS 390
Score = 33.1 bits (72), Expect = 0.92
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD N F FS GKR C+G+ A M + L +L+ + +
Sbjct: 405 EMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 60.1 bits (139), Expect = 7e-09
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Frame = -1
Query: 531 ATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEAT 355
A + AG +T TL Y L+ + HP V ++ EE+++V+G + Q+ + Y +A
Sbjct: 292 ADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAV 351
Query: 354 IKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
+ E R + P + CDVK RN IP G ++ S
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTS 390
Score = 33.1 bits (72), Expect = 0.92
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Frame = -2
Query: 209 EHFKPERWLDP--TTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
E F P +LD N F FS GKR C+G+ A M + L +L+ + +
Sbjct: 405 EMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL 458
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 60.1 bits (139), Expect = 7e-09
Identities = 38/128 (29%), Positives = 64/128 (50%), Gaps = 3/128 (2%)
Frame = -1
Query: 615 GEQKPFIDLXIEI--AEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQ 442
GE+ P D+ +I AEE D ++ TF AGH+T L +T+M + P +
Sbjct: 268 GEEVP-ADILTQILKAEEGAQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVA 326
Query: 441 RIYEELQQVLGSDD-VTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIP 265
R+ E+ +V+GS + ++L L YL +KE++RLYP A R+ + + + +P
Sbjct: 327 RLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVP 386
Query: 264 SGASVALS 241
+ S
Sbjct: 387 GNTPLLFS 394
Score = 39.9 bits (89), Expect = 0.008
Identities = 18/47 (38%), Positives = 27/47 (57%)
Frame = -2
Query: 203 FKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
F P+R+ P + FS G R+CIG+ FA M +K +A LL++
Sbjct: 411 FNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQR 457
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 59.7 bits (138), Expect = 9e-09
Identities = 30/100 (30%), Positives = 56/100 (56%), Gaps = 1/100 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QN 385
LS E + L + AG DT TL + L + P +Q+ ++EE+ V+ + V + ++
Sbjct: 319 LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKD 378
Query: 384 LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIP 265
+ + L+A +KET+RLYP+ P SR+ + ++++ P
Sbjct: 379 FAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFP 418
Score = 38.3 bits (85), Expect = 0.024
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 6/65 (9%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWL---DPTTLP-ENAFAG--FSTGKRNCIGKTFAMMSMKTTLAHLL 69
P S+ E F+P RWL P T ++ F F G R C+G+ A + M+ LA L+
Sbjct: 434 PTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLI 493
Query: 68 RQYRV 54
++Y+V
Sbjct: 494 QKYKV 498
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 59.7 bits (138), Expect = 9e-09
Identities = 30/100 (30%), Positives = 56/100 (56%), Gaps = 1/100 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QN 385
LS E + L + AG DT TL + L + P +Q+ ++EE+ V+ + V + ++
Sbjct: 320 LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKD 379
Query: 384 LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIP 265
+ + L+A +KET+RLYP+ P SR+ + ++++ P
Sbjct: 380 FAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFP 419
Score = 38.3 bits (85), Expect = 0.024
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 6/65 (9%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWL---DPTTLP-ENAFAG--FSTGKRNCIGKTFAMMSMKTTLAHLL 69
P S+ E F+P RWL P T ++ F F G R C+G+ A + M+ LA L+
Sbjct: 435 PTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLI 494
Query: 68 RQYRV 54
++Y+V
Sbjct: 495 QKYKV 499
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 59.7 bits (138), Expect = 9e-09
Identities = 30/100 (30%), Positives = 56/100 (56%), Gaps = 1/100 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QN 385
LS E + L + AG DT TL + L + P +Q+ ++EE+ V+ + V + ++
Sbjct: 320 LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKD 379
Query: 384 LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIP 265
+ + L+A +KET+RLYP+ P SR+ + ++++ P
Sbjct: 380 FAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFP 419
Score = 38.3 bits (85), Expect = 0.024
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 6/65 (9%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWL---DPTTLP-ENAFAG--FSTGKRNCIGKTFAMMSMKTTLAHLL 69
P S+ E F+P RWL P T ++ F F G R C+G+ A + M+ LA L+
Sbjct: 435 PTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLI 494
Query: 68 RQYRV 54
++Y+V
Sbjct: 495 QKYKV 499
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 59.7 bits (138), Expect = 9e-09
Identities = 30/100 (30%), Positives = 56/100 (56%), Gaps = 1/100 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QN 385
LS E + L + AG DT TL + L + P +Q+ ++EE+ V+ + V + ++
Sbjct: 320 LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKD 379
Query: 384 LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIP 265
+ + L+A +KET+RLYP+ P SR+ + ++++ P
Sbjct: 380 FAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFP 419
Score = 38.3 bits (85), Expect = 0.024
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 6/65 (9%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWL---DPTTLP-ENAFAG--FSTGKRNCIGKTFAMMSMKTTLAHLL 69
P S+ E F+P RWL P T ++ F F G R C+G+ A + M+ LA L+
Sbjct: 435 PTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLI 494
Query: 68 RQYRV 54
++Y+V
Sbjct: 495 QKYKV 499
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 59.3 bits (137), Expect = 1e-08
Identities = 30/100 (30%), Positives = 56/100 (56%), Gaps = 1/100 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QN 385
LS E + L + AG DT TL + L + P +Q+ ++EE+ V+ + V + ++
Sbjct: 320 LSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQVPQHKD 379
Query: 384 LSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIP 265
+ + L+A +KET+RLYP+ P SR+ + ++++ P
Sbjct: 380 FAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFP 419
Score = 38.3 bits (85), Expect = 0.024
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 6/65 (9%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWL---DPTTLP-ENAFAG--FSTGKRNCIGKTFAMMSMKTTLAHLL 69
P S+ E F+P RWL P T ++ F F G R C+G+ A + M+ LA L+
Sbjct: 435 PTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLI 494
Query: 68 RQYRV 54
++Y+V
Sbjct: 495 QKYKV 499
>AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
Homo sapiens cholesterol 24-hydroxylase mRNA. ).
Length = 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 35/101 (34%), Positives = 55/101 (54%), Gaps = 3/101 (2%)
Frame = -1
Query: 615 GEQKPFIDLXIEI--AEEKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQ 442
GE+ P D+ +I AEE D ++ TF AGH+T L +T+M + P +
Sbjct: 115 GEEVP-ADILTQILKAEEGAQDDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVA 173
Query: 441 RIYEELQQVLGSDD-VTKQNLSSLVYLEATIKETMRLYPIA 322
R+ E+ +V+GS + ++L L YL +KE++RLYP A
Sbjct: 174 RLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKESLRLYPPA 214
Score = 39.9 bits (89), Expect = 0.008
Identities = 18/47 (38%), Positives = 27/47 (57%)
Frame = -2
Query: 203 FKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
F P+R+ P + FS G R+CIG+ FA M +K +A LL++
Sbjct: 248 FNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQR 294
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 58.0 bits (134), Expect = 3e-08
Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = -1
Query: 522 IAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKE 346
+ AG +T TL + + +G HP VQ R+ EEL +VLG + ++ +L Y A + E
Sbjct: 294 VMAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVLGPGRTPRLEDQQALPYTSAVLHE 353
Query: 345 TMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
R + P V R T D +L +P G V
Sbjct: 354 VQRFITLLPHVPRCTAADTQLGGFLLPKGTPV 385
Score = 34.7 bits (76), Expect = 0.30
Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Frame = -2
Query: 203 FKPERWLDPTT--LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRME 30
F P +LD + AF FS G+R C+G+ A + A LL++YR+
Sbjct: 405 FNPGHFLDANGHFVKREAFLPFSAGRRVCVGERLARTELFLLFAGLLQRYRLLPPPGVSP 464
Query: 29 AKLD 18
A LD
Sbjct: 465 ASLD 468
>AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens
cDNA FLJ20359 fis, clone HEP16626. ).
Length = 408
Score = 58.0 bits (134), Expect = 3e-08
Identities = 31/92 (33%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Frame = -1
Query: 522 IAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKE 346
+ AG +T TL + + +G HP VQ R+ EEL +VLG + ++ +L Y A + E
Sbjct: 238 VMAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVLGPGRTPRLEDQQALPYTSAVLHE 297
Query: 345 TMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
R + P V R T D +L +P G V
Sbjct: 298 VQRFITLLPHVPRCTAADTQLGGFLLPKGTPV 329
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 57.2 bits (132), Expect = 5e-08
Identities = 38/106 (35%), Positives = 55/106 (51%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R + P + T D L+ IP G V
Sbjct: 362 RSHLPYMEAFILETFRHSSLVPFTIPHSTTRDTSLKGFYIPKGRCV 407
Score = 33.5 bits (73), Expect = 0.69
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPENAFAG----FSTGKRNCIGKTFAMMSMKTTLAHL 72
H +W + E F PER+L P + + F GKR CIG+T A + LA L
Sbjct: 416 HDQKLWVNPSE-FLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETVARWEVFLFLAIL 474
Query: 71 LRQ 63
L++
Sbjct: 475 LQR 477
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 57.2 bits (132), Expect = 5e-08
Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++ + AG +T + +TL + +P V++++YEE+ Q +G S T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISD 346
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASVALS 241
+ L+ LEATI+E +RL P+AP ++ + D + + G V ++
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIIN 395
Score = 39.1 bits (87), Expect = 0.014
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDP--TTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAH 75
LHH+ + F PER+L+P T L P ++ F G R+CIG+ A + +A
Sbjct: 399 LHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAW 458
Query: 74 LLRQY 60
LL+++
Sbjct: 459 LLQRF 463
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 57.2 bits (132), Expect = 5e-08
Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++ + AG +T + +TL + +P V++++YEE+ Q +G S T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISD 346
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASVALS 241
+ L+ LEATI+E +RL P+AP ++ + D + + G V ++
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIIN 395
Score = 39.1 bits (87), Expect = 0.014
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDP--TTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAH 75
LHH+ + F PER+L+P T L P ++ F G R+CIG+ A + +A
Sbjct: 399 LHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAW 458
Query: 74 LLRQY 60
LL+++
Sbjct: 459 LLQRF 463
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 57.2 bits (132), Expect = 5e-08
Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++ + AG +T + +TL + +P V++++YEE+ Q +G S T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISD 346
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASVALS 241
+ L+ LEATI+E +RL P+AP ++ + D + + G V ++
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIIN 395
Score = 39.1 bits (87), Expect = 0.014
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDP--TTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAH 75
LHH+ + F PER+L+P T L P ++ F G R+CIG+ A + +A
Sbjct: 399 LHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAW 458
Query: 74 LLRQY 60
LL+++
Sbjct: 459 LLQRF 463
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 57.2 bits (132), Expect = 5e-08
Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++ + AG +T + +TL + +P V++++YEE+ Q +G S T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISD 346
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASVALS 241
+ L+ LEATI+E +RL P+AP ++ + D + + G V ++
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIIN 395
Score = 39.1 bits (87), Expect = 0.014
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDP--TTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAH 75
LHH+ + F PER+L+P T L P ++ F G R+CIG+ A + +A
Sbjct: 399 LHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAW 458
Query: 74 LLRQY 60
LL+++
Sbjct: 459 LLQRF 463
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 57.2 bits (132), Expect = 5e-08
Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++ + AG +T + +TL + +P V++++YEE+ Q +G S T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISD 346
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASVALS 241
+ L+ LEATI+E +RL P+AP ++ + D + + G V ++
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIIN 395
Score = 39.1 bits (87), Expect = 0.014
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDP--TTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAH 75
LHH+ + F PER+L+P T L P ++ F G R+CIG+ A + +A
Sbjct: 399 LHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAW 458
Query: 74 LLRQY 60
LL+++
Sbjct: 459 LLQRF 463
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 57.2 bits (132), Expect = 5e-08
Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++ + AG +T + +TL + +P V++++YEE+ Q +G S T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISD 346
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASVALS 241
+ L+ LEATI+E +RL P+AP ++ + D + + G V ++
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIIN 395
Score = 39.1 bits (87), Expect = 0.014
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDP--TTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAH 75
LHH+ + F PER+L+P T L P ++ F G R+CIG+ A + +A
Sbjct: 399 LHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAW 458
Query: 74 LLRQY 60
LL+++
Sbjct: 459 LLQRF 463
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 57.2 bits (132), Expect = 5e-08
Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++ + AG +T + +TL + +P V++++YEE+ Q +G S T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISD 346
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASVALS 241
+ L+ LEATI+E +RL P+AP ++ + D + + G V ++
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIIN 395
Score = 39.1 bits (87), Expect = 0.014
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDP--TTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAH 75
LHH+ + F PER+L+P T L P ++ F G R+CIG+ A + +A
Sbjct: 399 LHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAW 458
Query: 74 LLRQY 60
LL+++
Sbjct: 459 LLQRF 463
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 57.2 bits (132), Expect = 5e-08
Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++ + AG +T + +TL + +P V++++YEE+ Q +G S T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISD 346
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASVALS 241
+ L+ LEATI+E +RL P+AP ++ + D + + G V ++
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIIN 395
Score = 39.1 bits (87), Expect = 0.014
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDP--TTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAH 75
LHH+ + F PER+L+P T L P ++ F G R+CIG+ A + +A
Sbjct: 399 LHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAW 458
Query: 74 LLRQY 60
LL+++
Sbjct: 459 LLQRF 463
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 57.2 bits (132), Expect = 5e-08
Identities = 32/109 (29%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++ + AG +T + +TL + +P V++++YEE+ Q +G S T +
Sbjct: 287 LSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISD 346
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASVALS 241
+ L+ LEATI+E +RL P+AP ++ + D + + G V ++
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIIN 395
Score = 39.1 bits (87), Expect = 0.014
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDP--TTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAH 75
LHH+ + F PER+L+P T L P ++ F G R+CIG+ A + +A
Sbjct: 399 LHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAW 458
Query: 74 LLRQY 60
LL+++
Sbjct: 459 LLQRF 463
>Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for
aromatase P-450. ).
Length = 503
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = -1
Query: 579 IAEEKGLSDMEVIHE-LATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
+AE++G E +++ + + A DT+ +L + L + HP V++ I +E+Q V+G
Sbjct: 284 LAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER 343
Query: 402 DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVALS 241
D+ ++ L +E I E+MR P+ +V R D + + G ++ L+
Sbjct: 344 DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN 397
Score = 35.9 bits (79), Expect = 0.13
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 170 LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
+P F F G R C GK AM+ MK L LLR++ V
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460
>X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for
aromatase (estrogen synthetase). ).
Length = 503
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = -1
Query: 579 IAEEKGLSDMEVIHE-LATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
+AE++G E +++ + + A DT+ +L + L + HP V++ I +E+Q V+G
Sbjct: 284 LAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER 343
Query: 402 DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVALS 241
D+ ++ L +E I E+MR P+ +V R D + + G ++ L+
Sbjct: 344 DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN 397
Score = 35.9 bits (79), Expect = 0.13
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 170 LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
+P F F G R C GK AM+ MK L LLR++ V
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 407
Score = 33.9 bits (74), Expect = 0.52
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPENAFAG----FSTGKRNCIGKTFAMMSMKTTLAHL 72
H +W + E F PER+L P + + F GKR CIG+T A + LA L
Sbjct: 416 HDQKLWVNPSE-FLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAIL 474
Query: 71 LRQ 63
L++
Sbjct: 475 LQR 477
>M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase
cytochrome P-450 gene, exon 10. ).
Length = 503
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = -1
Query: 579 IAEEKGLSDMEVIHE-LATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
+AE++G E +++ + + A DT+ +L + L + HP V++ I +E+Q V+G
Sbjct: 284 LAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER 343
Query: 402 DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVALS 241
D+ ++ L +E I E+MR P+ +V R D + + G ++ L+
Sbjct: 344 DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN 397
Score = 35.9 bits (79), Expect = 0.13
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 170 LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
+P F F G R C GK AM+ MK L LLR++ V
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460
>M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatase
protein.
Length = 419
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = -1
Query: 579 IAEEKGLSDMEVIHE-LATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
+AE++G E +++ + + A DT+ +L + L + HP V++ I +E+Q V+G
Sbjct: 200 LAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER 259
Query: 402 DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVALS 241
D+ ++ L +E I E+MR P+ +V R D + + G ++ L+
Sbjct: 260 DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN 313
Score = 35.9 bits (79), Expect = 0.13
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 170 LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
+P F F G R C GK AM+ MK L LLR++ V
Sbjct: 338 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 376
>M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase
mRNA, complete cds. ).
Length = 503
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = -1
Query: 579 IAEEKGLSDMEVIHE-LATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
+AE++G E +++ + + A DT+ +L + L + HP V++ I +E+Q V+G
Sbjct: 284 LAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER 343
Query: 402 DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVALS 241
D+ ++ L +E I E+MR P+ +V R D + + G ++ L+
Sbjct: 344 DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN 397
Score = 35.9 bits (79), Expect = 0.13
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 170 LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
+P F F G R C GK AM+ MK L LLR++ V
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460
>M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase
(Aro1) mRNA, complete cds. ).
Length = 419
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = -1
Query: 579 IAEEKGLSDMEVIHE-LATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
+AE++G E +++ + + A DT+ +L + L + HP V++ I +E+Q V+G
Sbjct: 200 LAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER 259
Query: 402 DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVALS 241
D+ ++ L +E I E+MR P+ +V R D + + G ++ L+
Sbjct: 260 DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN 313
Score = 35.9 bits (79), Expect = 0.13
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 170 LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
+P F F G R C GK AM+ MK L LLR++ V
Sbjct: 338 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 376
>M12079-1|AAA52152.1| 191|Homo sapiens POR protein.
Length = 191
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 8 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 67
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 68 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 113
Score = 33.5 bits (73), Expect = 0.69
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPENAFAG----FSTGKRNCIGKTFAMMSMKTTLAHL 72
H +W + E F PER+L P + + F GKR CIG+T A + LA L
Sbjct: 122 HDQKLWVNPSE-FLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETVARWEVFLFLAIL 180
Query: 71 LRQ 63
L++
Sbjct: 181 LQR 183
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 407
Score = 33.5 bits (73), Expect = 0.69
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPENAFAG----FSTGKRNCIGKTFAMMSMKTTLAHL 72
H +W + E F PER+L P + + F GKR CIG+T A + LA L
Sbjct: 416 HDQKLWVNPSE-FLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETVARWEVFLFLAIL 474
Query: 71 LRQ 63
L++
Sbjct: 475 LQR 477
>J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein.
Length = 503
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = -1
Query: 579 IAEEKGLSDMEVIHE-LATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
+AE++G E +++ + + A DT+ +L + L + HP V++ I +E+Q V+G
Sbjct: 284 LAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER 343
Query: 402 DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVALS 241
D+ ++ L +E I E+MR P+ +V R D + + G ++ L+
Sbjct: 344 DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN 397
Score = 35.9 bits (79), Expect = 0.13
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 170 LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
+P F F G R C GK AM+ MK L LLR++ V
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 407
Score = 33.9 bits (74), Expect = 0.52
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPENAFAG----FSTGKRNCIGKTFAMMSMKTTLAHL 72
H +W + E F PER+L P + + F GKR CIG+T A + LA L
Sbjct: 416 HDQKLWVNPSE-FLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAIL 474
Query: 71 LRQ 63
L++
Sbjct: 475 LQR 477
>DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfamily
19 subfamily A polypeptide 1 protein.
Length = 503
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = -1
Query: 579 IAEEKGLSDMEVIHE-LATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
+AE++G E +++ + + A DT+ +L + L + HP V++ I +E+Q V+G
Sbjct: 284 LAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER 343
Query: 402 DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVALS 241
D+ ++ L +E I E+MR P+ +V R D + + G ++ L+
Sbjct: 344 DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN 397
Score = 35.9 bits (79), Expect = 0.13
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 170 LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
+P F F G R C GK AM+ MK L LLR++ V
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 56.4 bits (130), Expect = 9e-08
Identities = 29/91 (31%), Positives = 55/91 (60%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDV-TKQNLSSLVYLEATIKETM 340
AG DT +LL+ L+ + +P VQ++++EE+++V+G++ + + + + Y EATI E
Sbjct: 352 AGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQ 411
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
RL + P+ + +T + L+ TIP G +
Sbjct: 412 RLTVVVPLAIPHMTSENTVLQGYTIPKGTLI 442
Score = 34.3 bits (75), Expect = 0.40
Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPT--TLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
+H P E F P R+LD + + F F GKR C+G+ A M + L+
Sbjct: 449 VHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLM 508
Query: 68 RQY 60
+ +
Sbjct: 509 QSF 511
>BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = -1
Query: 579 IAEEKGLSDMEVIHE-LATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
+AE++G E +++ + + A DT+ +L + L + HP V++ I +E+Q V+G
Sbjct: 284 LAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER 343
Query: 402 DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVALS 241
D+ ++ L +E I E+MR P+ +V R D + + G ++ L+
Sbjct: 344 DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN 397
Score = 35.9 bits (79), Expect = 0.13
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 170 LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
+P F F G R C GK AM+ MK L LLR++ V
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460
>BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = -1
Query: 579 IAEEKGLSDMEVIHE-LATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
+AE++G E +++ + + A DT+ +L + L + HP V++ I +E+Q V+G
Sbjct: 284 LAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER 343
Query: 402 DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVALS 241
D+ ++ L +E I E+MR P+ +V R D + + G ++ L+
Sbjct: 344 DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN 397
Score = 35.9 bits (79), Expect = 0.13
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 170 LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
+P F F G R C GK AM+ MK L LLR++ V
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 407
Score = 33.9 bits (74), Expect = 0.52
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPENAFAG----FSTGKRNCIGKTFAMMSMKTTLAHL 72
H +W + E F PER+L P + + F GKR CIG+T A + LA L
Sbjct: 416 HDQKLWVNPSE-FLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAIL 474
Query: 71 LRQ 63
L++
Sbjct: 475 LQR 477
>AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 56.4 bits (130), Expect = 9e-08
Identities = 30/114 (26%), Positives = 59/114 (51%), Gaps = 1/114 (0%)
Frame = -1
Query: 579 IAEEKGLSDMEVIHE-LATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD 403
+AE++G E +++ + + A DT+ +L + L + HP V++ I +E+Q V+G
Sbjct: 284 LAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGER 343
Query: 402 DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVALS 241
D+ ++ L +E I E+MR P+ +V R D + + G ++ L+
Sbjct: 344 DIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILN 397
Score = 35.9 bits (79), Expect = 0.13
Identities = 17/39 (43%), Positives = 21/39 (53%)
Frame = -2
Query: 170 LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRV 54
+P F F G R C GK AM+ MK L LLR++ V
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRFHV 460
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 56.4 bits (130), Expect = 9e-08
Identities = 29/91 (31%), Positives = 55/91 (60%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDV-TKQNLSSLVYLEATIKETM 340
AG DT +LL+ L+ + +P VQ++++EE+++V+G++ + + + + Y EATI E
Sbjct: 352 AGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQ 411
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
RL + P+ + +T + L+ TIP G +
Sbjct: 412 RLTVVVPLAIPHMTSENTVLQGYTIPKGTLI 442
Score = 34.3 bits (75), Expect = 0.40
Identities = 18/63 (28%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPT--TLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLL 69
+H P E F P R+LD + + F F GKR C+G+ A M + L+
Sbjct: 449 VHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLM 508
Query: 68 RQY 60
+ +
Sbjct: 509 QSF 511
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 274 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 333
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 334 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 379
Score = 33.9 bits (74), Expect = 0.52
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPENAFAG----FSTGKRNCIGKTFAMMSMKTTLAHL 72
H +W + E F PER+L P + + F GKR CIG+T A + LA L
Sbjct: 388 HDQKLWVNPSE-FLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAIL 446
Query: 71 LRQ 63
L++
Sbjct: 447 LQR 449
>AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1
protein.
Length = 251
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 41 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 100
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 101 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 146
Score = 33.9 bits (74), Expect = 0.52
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPENAFAG----FSTGKRNCIGKTFAMMSMKTTLAHL 72
H +W + E F PER+L P + + F GKR CIG+T A + LA L
Sbjct: 155 HDQKLWVNPSE-FLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAIL 213
Query: 71 LRQ 63
L++
Sbjct: 214 LQR 216
>AM233518-1|CAJ80721.1| 157|Homo sapiens cytochrome P450 1A1
protein.
Length = 157
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 41 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 100
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 101 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 146
>AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1
protein.
Length = 175
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 41 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 100
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 101 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 146
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 407
Score = 33.9 bits (74), Expect = 0.52
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPENAFAG----FSTGKRNCIGKTFAMMSMKTTLAHL 72
H +W + E F PER+L P + + F GKR CIG+T A + LA L
Sbjct: 416 HDQKLWVNPSE-FLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAIL 474
Query: 71 LRQ 63
L++
Sbjct: 475 LQR 477
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 407
Score = 33.9 bits (74), Expect = 0.52
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPENAFAG----FSTGKRNCIGKTFAMMSMKTTLAHL 72
H +W + E F PER+L P + + F GKR CIG+T A + LA L
Sbjct: 416 HDQKLWVNPSE-FLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAIL 474
Query: 71 LRQ 63
L++
Sbjct: 475 LQR 477
>AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1
protein.
Length = 144
Score = 56.4 bits (130), Expect = 9e-08
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV + ++LM + +P VQ++I EEL V+G S +
Sbjct: 21 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 80
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 81 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 126
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 56.0 bits (129), Expect = 1e-07
Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Frame = -1
Query: 552 MEVIHELATFIAAGH-DTVPYTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLS 379
+E I + + AG DT + LL TL + +P VQQ + +E L + ++ +
Sbjct: 301 LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATT 360
Query: 378 SLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
L L A +KET+RLYP+ + RV D+ L+N IP+G V
Sbjct: 361 ELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLV 403
Score = 38.3 bits (85), Expect = 0.024
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Frame = -2
Query: 209 EHFKPERWLDPTTLPENAF-AGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRM 33
E + P+RWLD N F G R C+G+ A M L H+L+ + V +T+
Sbjct: 421 ERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVET-LTQE 479
Query: 32 EAKL--DIILKP 3
+ K+ IL+P
Sbjct: 480 DIKMVYSFILRP 491
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 56.0 bits (129), Expect = 1e-07
Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Frame = -1
Query: 552 MEVIHELATFIAAGH-DTVPYTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLS 379
+E I + + AG DT + LL TL + +P VQQ + +E L + ++ +
Sbjct: 301 LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATT 360
Query: 378 SLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
L L A +KET+RLYP+ + RV D+ L+N IP+G V
Sbjct: 361 ELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLV 403
Score = 38.3 bits (85), Expect = 0.024
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Frame = -2
Query: 209 EHFKPERWLDPTTLPENAF-AGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRM 33
E + P+RWLD N F G R C+G+ A M L H+L+ + V +T+
Sbjct: 421 ERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVET-LTQE 479
Query: 32 EAKL--DIILKP 3
+ K+ IL+P
Sbjct: 480 DIKMVYSFILRP 491
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 55.6 bits (128), Expect = 2e-07
Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Frame = -1
Query: 552 MEVIHELATFIAAGH-DTVPYTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLS 379
+E I + + AG DT + LL TL + +P VQQ + +E L + ++ +
Sbjct: 301 LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRKESLAAAASISEHPQKATT 360
Query: 378 SLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
L L A +KET+RLYP+ + RV D+ L+N IP+G V
Sbjct: 361 ELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLV 403
Score = 39.1 bits (87), Expect = 0.014
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Frame = -2
Query: 209 EHFKPERWLDPTTLPENAF-AGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRM 33
E + P+RWLD N F G R C+G+ A M L H+L+++ V +T+
Sbjct: 421 ERYNPQRWLDIRGSGRNLHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKRFLVET-LTQE 479
Query: 32 EAKL--DIILKP 3
+ K+ IL+P
Sbjct: 480 DIKMVYSFILRP 491
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 55.6 bits (128), Expect = 2e-07
Identities = 28/70 (40%), Positives = 39/70 (55%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPTTLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
LHH+P ++E F P R+ + +AF FS G RNCIGK FAM +K A L +
Sbjct: 320 LHHNPKVWPNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLR 379
Query: 62 YRVTADITRM 33
+ + D TR+
Sbjct: 380 FELLPDPTRI 389
Score = 33.1 bits (72), Expect = 0.92
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Frame = -1
Query: 459 HPPVQQRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPVVSRVTDCDVKL 283
HPP+ QR + S + + +L + Y IKE +RLYP P + R V
Sbjct: 242 HPPLGQRAPGLPRPCWCSGWNCFRNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTF 301
Query: 282 RNS-TIPSGASVALS 241
+ ++P G V LS
Sbjct: 302 PDGRSLPKGIMVLLS 316
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 55.6 bits (128), Expect = 2e-07
Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -1
Query: 519 AAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLSSLVYLEATIKET 343
A DT + LL TL + +P VQQ + +E L + ++ + L L A +KET
Sbjct: 313 AGSMDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKET 372
Query: 342 MRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
+RLYP+ + RV D+ L+N IP+G V
Sbjct: 373 LRLYPVGLFLERVASSDLVLQNYHIPAGTLV 403
Score = 39.5 bits (88), Expect = 0.011
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Frame = -2
Query: 209 EHFKPERWLDPTTLPENAF-AGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRM 33
E + P+RWLD N + F G R C+G+ A M L H+L+ +V +T+
Sbjct: 421 ERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVET-LTQE 479
Query: 32 EAKL--DIILKP 3
+ K+ IL+P
Sbjct: 480 DIKMVYSFILRP 491
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 55.2 bits (127), Expect = 2e-07
Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -1
Query: 519 AAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLSSLVYLEATIKET 343
A DT + LL TL + +P VQQ + +E L + ++ + L L A +KET
Sbjct: 313 AGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKET 372
Query: 342 MRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
+RLYP+ + RV D+ L+N IP+G V
Sbjct: 373 LRLYPVGLFLERVVSSDLVLQNYHIPAGTLV 403
Score = 39.5 bits (88), Expect = 0.011
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Frame = -2
Query: 209 EHFKPERWLDPTTLPENAF-AGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRM 33
E + P+RWLD N + F G R C+G+ A M L H+L+ +V +T+
Sbjct: 421 ERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVET-LTQE 479
Query: 32 EAKL--DIILKP 3
+ K+ IL+P
Sbjct: 480 DIKMVYSFILRP 491
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 55.2 bits (127), Expect = 2e-07
Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETM 340
AG +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + + Y+EA I E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQ 360
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
R + P+ ++R D K R+ +P G V
Sbjct: 361 RFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 391
>S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase
protein.
Length = 228
Score = 55.2 bits (127), Expect = 2e-07
Identities = 34/100 (34%), Positives = 53/100 (53%), Gaps = 2/100 (2%)
Frame = -1
Query: 552 MEVIHELATFIAAGH-DTVPYTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLS 379
+E I + + AG DT + LL TL + +P VQQ + +E L + ++ +
Sbjct: 129 LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATT 188
Query: 378 SLVYLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSG 259
L L A +KET+RLYP+ + RV D+ L+N IP+G
Sbjct: 189 ELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAG 228
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 55.2 bits (127), Expect = 2e-07
Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETM 340
AG +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + + Y+EA I E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQ 360
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
R + P+ ++R D K R+ +P G V
Sbjct: 361 RFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 391
Score = 33.9 bits (74), Expect = 0.52
Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + F P+ +LD +AF FS GKR C G+ A M + +++ +R
Sbjct: 402 PSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFR 461
Query: 56 V 54
+
Sbjct: 462 L 462
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 55.2 bits (127), Expect = 2e-07
Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -1
Query: 519 AAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLSSLVYLEATIKET 343
A DT + LL TL + +P VQQ + +E L + ++ + L L A +KET
Sbjct: 313 AGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKET 372
Query: 342 MRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
+RLYP+ + RV D+ L+N IP+G V
Sbjct: 373 LRLYPVGLFLERVASSDLVLQNYHIPAGTLV 403
Score = 39.5 bits (88), Expect = 0.011
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Frame = -2
Query: 209 EHFKPERWLDPTTLPENAF-AGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRM 33
E + P+RWLD N + F G R C+G+ A M L H+L+ +V +T+
Sbjct: 421 ERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVET-LTQE 479
Query: 32 EAKL--DIILKP 3
+ K+ IL+P
Sbjct: 480 DIKMVYSFILRP 491
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 55.2 bits (127), Expect = 2e-07
Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETM 340
AG +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + + Y+EA I E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQ 360
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
R + P+ ++R D K R+ +P G V
Sbjct: 361 RFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 391
Score = 33.9 bits (74), Expect = 0.52
Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + F P+ +LD +AF FS GKR C G+ A M + +++ +R
Sbjct: 402 PSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFR 461
Query: 56 V 54
+
Sbjct: 462 L 462
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 55.2 bits (127), Expect = 2e-07
Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -1
Query: 519 AAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLSSLVYLEATIKET 343
A DT + LL TL + +P VQQ + +E L + ++ + L L A +KET
Sbjct: 313 AGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKET 372
Query: 342 MRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
+RLYP+ + RV D+ L+N IP+G V
Sbjct: 373 LRLYPVGLFLERVASSDLVLQNYHIPAGTLV 403
Score = 39.5 bits (88), Expect = 0.011
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Frame = -2
Query: 209 EHFKPERWLDPTTLPENAF-AGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRM 33
E + P+RWLD N + F G R C+G+ A M L H+L+ +V +T+
Sbjct: 421 ERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVET-LTQE 479
Query: 32 EAKL--DIILKP 3
+ K+ IL+P
Sbjct: 480 DIKMVYSFILRP 491
>BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein.
Length = 574
Score = 55.2 bits (127), Expect = 2e-07
Identities = 32/91 (35%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -1
Query: 519 AAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLSSLVYLEATIKET 343
A DT + LL TL + +P VQQ + +E L + ++ + L L A +KET
Sbjct: 384 AGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKET 443
Query: 342 MRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
+RLYP+ + RV D+ L+N IP+G V
Sbjct: 444 LRLYPVGLFLERVASSDLVLQNYHIPAGTLV 474
Score = 39.5 bits (88), Expect = 0.011
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 3/72 (4%)
Frame = -2
Query: 209 EHFKPERWLDPTTLPENAF-AGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADITRM 33
E + P+RWLD N + F G R C+G+ A M L H+L+ +V +T+
Sbjct: 492 ERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVET-LTQE 550
Query: 32 EAKL--DIILKP 3
+ K+ IL+P
Sbjct: 551 DIKMVYSFILRP 562
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 55.2 bits (127), Expect = 2e-07
Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
Frame = -1
Query: 561 LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLG-SDDVTKQN 385
LSD ++I+ + AG DTV ++LM + +P VQ++I EEL V+G S +
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTATSWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 384 LSSLVYLEATIKETMRLYPIAP-VVSRVTDCDVKLRNSTIPSGASV 250
S L Y+EA I ET R P + T D L+ IP G V
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSLKGFYIPKGRCV 407
Score = 33.9 bits (74), Expect = 0.52
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 4/63 (6%)
Frame = -2
Query: 239 HHHPVWGSDVEHFKPERWLDPTTLPENAFAG----FSTGKRNCIGKTFAMMSMKTTLAHL 72
H +W + E F PER+L P + + F GKR CIG+T A + LA L
Sbjct: 416 HDQKLWVNPSE-FLPERFLTPDGAIDKVLSEKVIIFGMGKRKCIGETIARWEVFLFLAIL 474
Query: 71 LRQ 63
L++
Sbjct: 475 LQR 477
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 8/130 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDMEVIHE--LAT---FIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E E +AT AG +T TL Y L+ + +P V
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE++ V+G + Q+ S + Y +A + E R + P + CDVK +N
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYL 380
Query: 270 IPSGASVALS 241
IP G ++ S
Sbjct: 381 IPKGTTIITS 390
Score = 31.1 bits (67), Expect = 3.7
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Frame = -2
Query: 209 EHFKPERWLDPTT--LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADI 42
E F P +LD + + F FS GKR C+G+ A M + L +L+ + + + +
Sbjct: 405 EMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein.
Length = 443
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 8/130 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDMEVIHE--LAT---FIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E E +AT AG +T TL Y L+ + +P V
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE++ V+G + Q+ S + Y +A + E R + P + CDVK +N
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYL 380
Query: 270 IPSGASVALS 241
IP G ++ S
Sbjct: 381 IPKGTTIITS 390
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 8/130 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDMEVIHE--LAT---FIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E E +AT AG +T TL Y L+ + +P V
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE++ V+G + Q+ S + Y +A + E R + P + CDVK +N
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYL 380
Query: 270 IPSGASVALS 241
IP G ++ S
Sbjct: 381 IPKGTTIITS 390
Score = 31.1 bits (67), Expect = 3.7
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Frame = -2
Query: 209 EHFKPERWLDPTT--LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADI 42
E F P +LD + + F FS GKR C+G+ A M + L +L+ + + + +
Sbjct: 405 EMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 8/130 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDMEVIHE--LAT---FIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E E +AT AG +T TL Y L+ + +P V
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE++ V+G + Q+ S + Y +A + E R + P + CDVK +N
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYL 380
Query: 270 IPSGASVALS 241
IP G ++ S
Sbjct: 381 IPKGTTIITS 390
Score = 31.1 bits (67), Expect = 3.7
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Frame = -2
Query: 209 EHFKPERWLDPTT--LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADI 42
E F P +LD + + F FS GKR C+G+ A M + L +L+ + + + +
Sbjct: 405 EMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 8/130 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDMEVIHE--LAT---FIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E E +AT AG +T TL Y L+ + +P V
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE++ V+G + Q+ S + Y +A + E R + P + CDVK +N
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYL 380
Query: 270 IPSGASVALS 241
IP G ++ S
Sbjct: 381 IPKGTTIITS 390
Score = 31.1 bits (67), Expect = 3.7
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Frame = -2
Query: 209 EHFKPERWLDPTT--LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADI 42
E F P +LD + + F FS GKR C+G+ A M + L +L+ + + + +
Sbjct: 405 EMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 8/130 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDMEVIHE--LAT---FIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E E +AT AG +T TL Y L+ + +P V
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE++ V+G + Q+ S + Y +A + E R + P + CDVK +N
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYL 380
Query: 270 IPSGASVALS 241
IP G ++ S
Sbjct: 381 IPKGTTIITS 390
Score = 31.1 bits (67), Expect = 3.7
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Frame = -2
Query: 209 EHFKPERWLDPTT--LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADI 42
E F P +LD + + F FS GKR C+G+ A M + L +L+ + + + +
Sbjct: 405 EMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 54.8 bits (126), Expect = 3e-07
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 8/130 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDMEVIHE--LAT---FIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E E +AT AG +T TL Y L+ + +P V
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE++ V+G + Q+ S + Y +A + E R + P + CDVK +N
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYL 380
Query: 270 IPSGASVALS 241
IP G ++ S
Sbjct: 381 IPKGTTIITS 390
Score = 30.7 bits (66), Expect = 4.9
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Frame = -2
Query: 209 EHFKPERWLDPTT--LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADI 42
E F P +LD + + F FS GKR C+G+ A M + L +L+ + + + +
Sbjct: 405 EMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSKV 462
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 54.4 bits (125), Expect = 3e-07
Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 8/127 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDME-----VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E ++ +A AG +T TL Y L+ + HP V
Sbjct: 261 RDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE+ V+G Q+ S + Y +A + E R + P V D K RN
Sbjct: 321 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 380
Query: 270 IPSGASV 250
IP G ++
Sbjct: 381 IPKGTTI 387
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLV 370
V+ L FI G +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + +
Sbjct: 292 VMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMP 350
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
Y+EA I E R + P+ ++R D K R+ +P G V
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 391
Score = 35.1 bits (77), Expect = 0.23
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + F P+ +L+ +AF FS GKRNC G+ A M + +++ +R
Sbjct: 402 PSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFR 461
Query: 56 V 54
+
Sbjct: 462 L 462
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 54.4 bits (125), Expect = 3e-07
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLV 370
V+ L FI G +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + +
Sbjct: 246 VMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMP 304
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
Y+EA I E R + P+ ++R D K R+ +P G V
Sbjct: 305 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 345
Score = 35.1 bits (77), Expect = 0.23
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + F P+ +L+ +AF FS GKRNC G+ A M + +++ +R
Sbjct: 356 PSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFR 415
Query: 56 V 54
+
Sbjct: 416 L 416
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 29/91 (31%), Positives = 51/91 (56%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETM 340
AG +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + + Y+EA I E
Sbjct: 301 AGTETVSTTLHYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQ 360
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
R + P+ ++R D K R+ +P G V
Sbjct: 361 RFGDVIPMSLARRVKKDTKFRDFFLPKGIEV 391
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLV 370
V+ L FI G +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + +
Sbjct: 292 VMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMP 350
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
Y+EA I E R + P+ ++R D K R+ +P G V
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 391
Score = 35.1 bits (77), Expect = 0.23
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + F P+ +L+ +AF FS GKRNC G+ A M + +++ +R
Sbjct: 402 PSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFR 461
Query: 56 V 54
+
Sbjct: 462 L 462
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 54.4 bits (125), Expect = 3e-07
Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 8/127 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDME-----VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E ++ +A AG +T TL Y L+ + HP V
Sbjct: 233 RDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 292
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE+ V+G Q+ S + Y +A + E R + P V D K RN
Sbjct: 293 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 352
Query: 270 IPSGASV 250
IP G ++
Sbjct: 353 IPKGTTI 359
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 54.4 bits (125), Expect = 3e-07
Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 8/127 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDME-----VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E ++ +A AG +T TL Y L+ + HP V
Sbjct: 251 RDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 310
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE+ V+G Q+ S + Y +A + E R + P V D K RN
Sbjct: 311 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 370
Query: 270 IPSGASV 250
IP G ++
Sbjct: 371 IPKGTTI 377
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 54.4 bits (125), Expect = 3e-07
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 8/130 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDMEVIHE--LAT---FIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E E +AT AG +T TL Y L+ + +P V
Sbjct: 261 RDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE++ V+G + Q+ S + Y +A + E R + P + CDVK +N
Sbjct: 321 AKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYL 380
Query: 270 IPSGASVALS 241
IP G ++ S
Sbjct: 381 IPKGMTIITS 390
Score = 31.1 bits (67), Expect = 3.7
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Frame = -2
Query: 209 EHFKPERWLDPTT--LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADI 42
E F P +LD + + F FS GKR C+G+ A M + L +L+ + + + +
Sbjct: 405 EMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 462
>BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 437
Score = 54.4 bits (125), Expect = 3e-07
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 1/88 (1%)
Frame = -1
Query: 519 AAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLSSLVYLEATIKET 343
A DT + LL TL + +P VQQ + +E L + ++ + L L A +KET
Sbjct: 313 AGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKET 372
Query: 342 MRLYPIAPVVSRVTDCDVKLRNSTIPSG 259
+RLYP+ + RV D+ L+N IP+G
Sbjct: 373 LRLYPVGLFLERVASSDLVLQNYHIPAG 400
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLV 370
V+ L FI G +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + +
Sbjct: 292 VMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMP 350
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
Y+EA I E R + P+ ++R D K R+ +P G V
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 391
Score = 35.1 bits (77), Expect = 0.23
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + F P+ +L+ +AF FS GKRNC G+ A M + +++ +R
Sbjct: 402 PSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFR 461
Query: 56 V 54
+
Sbjct: 462 L 462
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLV 370
V+ L FI G +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + +
Sbjct: 292 VMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMP 350
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
Y+EA I E R + P+ ++R D K R+ +P G V
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 391
Score = 35.1 bits (77), Expect = 0.23
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + F P+ +L+ +AF FS GKRNC G+ A M + +++ +R
Sbjct: 402 PSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFR 461
Query: 56 V 54
+
Sbjct: 462 L 462
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLV 370
V+ L FI G +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + +
Sbjct: 292 VMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMP 350
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
Y+EA I E R + P+ ++R D K R+ +P G V
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 391
Score = 35.1 bits (77), Expect = 0.23
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + F P+ +L+ +AF FS GKRNC G+ A M + +++ +R
Sbjct: 402 PSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFR 461
Query: 56 V 54
+
Sbjct: 462 L 462
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLV 370
V+ L FI G +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + +
Sbjct: 292 VMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMP 350
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
Y+EA I E R + P+ ++R D K R+ +P G V
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 391
Score = 35.1 bits (77), Expect = 0.23
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + F P+ +L+ +AF FS GKRNC G+ A M + +++ +R
Sbjct: 402 PSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFR 461
Query: 56 V 54
+
Sbjct: 462 L 462
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 54.4 bits (125), Expect = 3e-07
Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 8/127 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDME-----VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E ++ +A AG +T TL Y L+ + HP V
Sbjct: 261 RDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE+ V+G Q+ S + Y +A + E R + P V D K RN
Sbjct: 321 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 380
Query: 270 IPSGASV 250
IP G ++
Sbjct: 381 IPKGTTI 387
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 54.4 bits (125), Expect = 3e-07
Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 8/127 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDME-----VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E ++ +A AG +T TL Y L+ + HP V
Sbjct: 261 RDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE+ V+G Q+ S + Y +A + E R + P V D K RN
Sbjct: 321 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 380
Query: 270 IPSGASV 250
IP G ++
Sbjct: 381 IPKGTTI 387
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 54.4 bits (125), Expect = 3e-07
Identities = 37/127 (29%), Positives = 58/127 (45%), Gaps = 8/127 (6%)
Frame = -1
Query: 606 KPFID-LXIEIAEEKGLSDME-----VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQ 445
+ FID I++ +EK E ++ +A AG +T TL Y L+ + HP V
Sbjct: 261 RDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVT 320
Query: 444 QRIYEELQQVLGSD-DVTKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNST 271
++ EE+ V+G Q+ S + Y +A + E R + P V D K RN
Sbjct: 321 AKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYL 380
Query: 270 IPSGASV 250
IP G ++
Sbjct: 381 IPKGTTI 387
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 54.4 bits (125), Expect = 3e-07
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLV 370
V+ L FI G +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + +
Sbjct: 292 VMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMP 350
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
Y+EA I E R + P+ ++R D K R+ +P G V
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 391
Score = 35.1 bits (77), Expect = 0.23
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + F P+ +L+ +AF FS GKRNC G+ A M + +++ +R
Sbjct: 402 PSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFR 461
Query: 56 V 54
+
Sbjct: 462 L 462
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 54.0 bits (124), Expect = 5e-07
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLV 370
V+ L FI G +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + +
Sbjct: 287 VMTTLNLFIG-GTETVSTTLRYGFLLLMKHPEVEAQVHEEIDRVIGKNRQPKFEDRAKMP 345
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
Y+EA I E R + P+ ++R D K R+ +P G V
Sbjct: 346 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEV 386
Score = 35.1 bits (77), Expect = 0.23
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + F P+ +L+ +AF FS GKRNC G+ A M + +++ +R
Sbjct: 397 PSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFR 456
Query: 56 V 54
+
Sbjct: 457 L 457
>M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxylase
protein.
Length = 256
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -1
Query: 519 AAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLSSLVYLEATIKET 343
A D + LL TL + +P VQQ + +E L + ++ + L L A +KET
Sbjct: 103 AGSVDRTVFPLLMTLFELARNPNVQQPLRQESLAPAASISEHPQKATTELPLLRAALKET 162
Query: 342 MRLYPIAPVVSRVTDCDVKLRNSTIPSGASV 250
+RLYP+ ++ RV D+ L+N IP+G V
Sbjct: 163 LRLYPVGLILERVVSSDLVLQNYHIPAGTLV 193
Score = 33.1 bits (72), Expect = 0.92
Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 1/46 (2%)
Frame = -2
Query: 209 EHFKPERWLDPTTLPENAF-AGFSTGKRNCIGKTFAMMSMKTTLAH 75
E + P+RWLD N + F G R C+G+ A M L H
Sbjct: 211 ERYNPQRWLDIKGSGRNFYHVPFGFGMRQCLGRRLAEADMLLLLQH 256
>BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein
protein.
Length = 310
Score = 54.0 bits (124), Expect = 5e-07
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLV 370
+I + AG +T TL Y L+ + +P V ++ EE++ V+G + Q+ S +
Sbjct: 107 LIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMP 166
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
Y +A + E R + P + CDVK +N IP G ++ S
Sbjct: 167 YTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITS 210
Score = 31.1 bits (67), Expect = 3.7
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Frame = -2
Query: 209 EHFKPERWLDPTT--LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADI 42
E F P +LD + + F FS GKR C+G+ A M + L +L+ + + + +
Sbjct: 225 EMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 282
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 54.0 bits (124), Expect = 5e-07
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLV 370
+I + AG +T TL Y L+ + +P V ++ EE++ V+G + Q+ S +
Sbjct: 228 LIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMP 287
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASVALS 241
Y +A + E R + P + CDVK +N IP G ++ S
Sbjct: 288 YTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITS 331
Score = 31.1 bits (67), Expect = 3.7
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%)
Frame = -2
Query: 209 EHFKPERWLDPTT--LPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYRVTADI 42
E F P +LD + + F FS GKR C+G+ A M + L +L+ + + + +
Sbjct: 346 EMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQV 403
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 54.0 bits (124), Expect = 5e-07
Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPT-TLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLR 66
LHH P + ++ E F+PER+ ++ + F TG RNCIG FA+M+MK L +L+
Sbjct: 72 LHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQ 131
Query: 65 QYRV-TADITRMEAKLD 18
+ T++ KLD
Sbjct: 132 NFSFKPCKETQIPLKLD 148
Score = 36.3 bits (80), Expect = 0.098
Identities = 15/42 (35%), Positives = 25/42 (59%)
Frame = -1
Query: 369 YLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
YL+ + ET+RL+P+A + R DV++ IP G+ V +
Sbjct: 26 YLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVI 67
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 54.0 bits (124), Expect = 5e-07
Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = -2
Query: 242 LHHHPVWGSDVEHFKPERWLDPT-TLPENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLR 66
LHH P + ++ E F+PER+ ++ + F TG RNCIG FA+M+MK L +L+
Sbjct: 59 LHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQ 118
Query: 65 QYRV-TADITRMEAKLD 18
+ T++ KLD
Sbjct: 119 NFSFKPCKETQIPLKLD 135
Score = 36.3 bits (80), Expect = 0.098
Identities = 15/42 (35%), Positives = 25/42 (59%)
Frame = -1
Query: 369 YLEATIKETMRLYPIAPVVSRVTDCDVKLRNSTIPSGASVAL 244
YL+ + ET+RL+P+A + R DV++ IP G+ V +
Sbjct: 13 YLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVI 54
>X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120
AA) protein.
Length = 210
Score = 53.6 bits (123), Expect = 6e-07
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLV 370
++ +A AG +T TL Y L+ + HP V ++ EE+ V+G Q+ S +
Sbjct: 7 LVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMP 66
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
Y +A + E R + P V D K RN IP G ++
Sbjct: 67 YTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTI 107
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 53.6 bits (123), Expect = 6e-07
Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLV 370
++ +A AG +T TL Y L+ + HP V ++ EE+ V+G Q+ S +
Sbjct: 287 LVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMP 346
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
Y +A + E R + P V D K RN IP G ++
Sbjct: 347 YTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTI 387
>K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein.
Length = 331
Score = 52.4 bits (120), Expect = 1e-06
Identities = 33/102 (32%), Positives = 55/102 (53%), Gaps = 3/102 (2%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLV 370
V+ L FI G +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + +
Sbjct: 129 VMTSLNLFIG-GTETVSTTLRYGFLLLIKHPGVEAKVHEEIDRVIGKNRQPKFEDRAKMP 187
Query: 369 YLEATIKETMRLYPIAPVV--SRVTDCDVKLRNSTIPSGASV 250
Y+EA I E R + P++ RV D K R+ +P G V
Sbjct: 188 YMEAMIHEIQRFGDVIPMIWPGRVKK-DTKFRDFFLPKGTEV 228
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETM 340
AG +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + + Y EA I E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQ 360
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
R + P+ ++ + D K R+ +P G V
Sbjct: 361 RFGDMLPMGLAHRVNKDTKFRDFFLPKGTEV 391
Score = 30.3 bits (65), Expect = 6.5
Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ + P+ +LD +AF FS GKR C G+ A M + +++ +R
Sbjct: 402 PRFFSNPQDCSPQHFLDEKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFR 461
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETM 340
AG +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + + Y EA I E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQ 360
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
R + P+ ++ + D K R+ +P G V
Sbjct: 361 RFGDMLPMGLAHRVNKDTKFRDFFLPKGTEV 391
Score = 32.7 bits (71), Expect = 1.2
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ F P+ +LD +AF FS GKR C G+ A M + +++ +R
Sbjct: 402 PRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFR 461
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETM 340
AG +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + + Y EA I E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQ 360
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
R + P+ ++ + D K R+ +P G V
Sbjct: 361 RFGDMLPMGLAHRVNKDTKFRDFFLPKGTEV 391
Score = 32.7 bits (71), Expect = 1.2
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ F P+ +LD +AF FS GKR C G+ A M + +++ +R
Sbjct: 402 PRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFR 461
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETM 340
AG +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + + Y EA I E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQ 360
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
R + P+ ++ + D K R+ +P G V
Sbjct: 361 RFGDMLPMGLAHRVNKDTKFRDFFLPKGTEV 391
Score = 32.7 bits (71), Expect = 1.2
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ F P+ +LD +AF FS GKR C G+ A M + +++ +R
Sbjct: 402 PRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFR 461
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETM 340
AG +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + + Y EA I E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQ 360
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
R + P+ ++ + D K R+ +P G V
Sbjct: 361 RFGDMLPMGLAHRVNKDTKFRDFFLPKGTEV 391
Score = 32.7 bits (71), Expect = 1.2
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ F P+ +LD +AF FS GKR C G+ A M + +++ +R
Sbjct: 402 PRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFR 461
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/91 (30%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETM 340
AG +TV TL Y + + HP V+ +++EE+ +V+G + K ++ + + Y EA I E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQ 360
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
R + P+ ++ + D K R+ +P G V
Sbjct: 361 RFGDMLPMGLAHRVNKDTKFRDFFLPKGTEV 391
Score = 32.7 bits (71), Expect = 1.2
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ F P+ +LD +AF FS GKR C G+ A M + +++ +R
Sbjct: 402 PRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFR 461
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 50.8 bits (116), Expect = 4e-06
Identities = 27/91 (29%), Positives = 50/91 (54%), Gaps = 2/91 (2%)
Frame = -1
Query: 516 AGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK-QNLSSLVYLEATIKETM 340
AG +TV TL Y + + HP ++ +++EE+ +V+G + K ++ + + Y EA I E
Sbjct: 301 AGTETVSTTLRYGFLLLMKHPELEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQ 360
Query: 339 RLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
R + P+ ++ + D K R+ +P G V
Sbjct: 361 RFGDMLPMGLAHRVNKDTKFRDFFLPKGTEV 391
Score = 32.7 bits (71), Expect = 1.2
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Frame = -2
Query: 230 PVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQYR 57
P + S+ F P+ +LD +AF FS GKR C G+ A M + +++ +R
Sbjct: 402 PRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFR 461
>AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens
cDNA FLJ36771 fis, clone ADRGL1000147, moderately
similar to CYTOCHROME P450 11B1 PRECURSOR (EC
1.14.15.4). ).
Length = 153
Score = 50.4 bits (115), Expect = 6e-06
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Frame = -1
Query: 495 YTLLYTLMCVGSHPPVQQRIYEE-LQQVLGSDDVTKQNLSSLVYLEATIKETMRLYPIAP 319
+ LL TL + +P VQQ + +E L + ++ + L L A +KET+RLYP+
Sbjct: 37 FPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGL 96
Query: 318 VVSRVTDCDVKLRNSTIPSG 259
+ RV D+ L+N IP+G
Sbjct: 97 FLERVASSDLVLQNYHIPAG 116
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 50.0 bits (114), Expect = 7e-06
Identities = 30/109 (27%), Positives = 56/109 (51%), Gaps = 2/109 (1%)
Frame = -1
Query: 570 EKGLSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSDDVTK 391
E +D + +A +AG T TL + L+ + HP VQ+R+ +E+ +V+G +
Sbjct: 287 ESSFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDEVIGQVRRPE 346
Query: 390 Q-NLSSLVYLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIPSGASV 250
+ + + Y A I E R I P+ V+ +T D++++ IP G ++
Sbjct: 347 MGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTL 395
Score = 33.5 bits (73), Expect = 0.69
Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Frame = -2
Query: 254 VSLCLHHHPVWGSDVEHFKPERWLDPTT--LPENAFAGFSTGKRNCIGKTFAMMSMKTTL 81
+S L VW F PE +LD + AF FS G+R C+G+ A M +
Sbjct: 399 LSSVLKDEAVWEKPFR-FHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFF 457
Query: 80 AHLLRQY 60
LL+ +
Sbjct: 458 TSLLQHF 464
>M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrome
P-450 1 mRNA, complete cds, clone Hp1-2. ).
Length = 393
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 2/96 (2%)
Frame = -1
Query: 546 VIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEELQQVLGSD-DVTKQNLSSLV 370
++ +A AG +T TL Y L+ + HP V ++ EE+ V+G Q+ S +
Sbjct: 287 LVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMP 346
Query: 369 YLEATIKETMRLYPIAPV-VSRVTDCDVKLRNSTIP 265
Y +A + E R + P V D K RN IP
Sbjct: 347 YTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIP 382
>D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV
protein.
Length = 389
Score = 49.6 bits (113), Expect = 1e-05
Identities = 30/92 (32%), Positives = 50/92 (54%), Gaps = 5/92 (5%)
Frame = -1
Query: 600 FIDLXIEIAEEKG--LSDMEVIHELATFIAAGHDTVPYTLLYTLMCVGSHPPVQQRIYEE 427
FID+ + +E G LSD ++ E TF+ GHDT L + L + HP Q+R +E
Sbjct: 298 FIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQE 357
Query: 426 LQQVLGS---DDVTKQNLSSLVYLEATIKETM 340
+Q++L ++ +L+ L +L IKE++
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCIKESL 389
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/136 (29%), Positives = 67/136 (49%), Gaps = 8/136 (5%)
Frame = -1
Query: 633 GTQDYSGEQKPFID-LXIEIAEEKGLSDMEVIHE--LATFIA---AGHDTVPYTLLYTLM 472
G D SG + +D +++A+E+ E ++ L T I AG TV T+ YTL+
Sbjct: 257 GNLDASGPARDLVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLL 316
Query: 471 CVGSHPPVQQRIYEELQQVLGSDDV-TKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTD 298
+ +P VQ+ + EEL + LG+ + + + L Y +A + E RL + P+ + R
Sbjct: 317 LLMKYPHVQKWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLM 376
Query: 297 CDVKLRNSTIPSGASV 250
+ R T+P G V
Sbjct: 377 RTTRFRGYTLPQGTEV 392
Score = 31.5 bits (68), Expect = 2.8
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 2/61 (3%)
Frame = -2
Query: 236 HHPVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
H P E F P+R+LD AF FS GKR C+G+ A + +L+
Sbjct: 401 HDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQA 460
Query: 62 Y 60
+
Sbjct: 461 F 461
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/136 (29%), Positives = 67/136 (49%), Gaps = 8/136 (5%)
Frame = -1
Query: 633 GTQDYSGEQKPFID-LXIEIAEEKGLSDMEVIHE--LATFIA---AGHDTVPYTLLYTLM 472
G D SG + +D +++A+E+ E ++ L T I AG TV T+ YTL+
Sbjct: 257 GNLDASGPARDLVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLL 316
Query: 471 CVGSHPPVQQRIYEELQQVLGSDDV-TKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTD 298
+ +P VQ+ + EEL + LG+ + + + L Y +A + E RL + P+ + R
Sbjct: 317 LLMKYPHVQKWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLM 376
Query: 297 CDVKLRNSTIPSGASV 250
+ R T+P G V
Sbjct: 377 RTTRFRGYTLPQGTEV 392
Score = 31.5 bits (68), Expect = 2.8
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 2/61 (3%)
Frame = -2
Query: 236 HHPVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
H P E F P+R+LD AF FS GKR C+G+ A + +L+
Sbjct: 401 HDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQA 460
Query: 62 Y 60
+
Sbjct: 461 F 461
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/136 (29%), Positives = 67/136 (49%), Gaps = 8/136 (5%)
Frame = -1
Query: 633 GTQDYSGEQKPFID-LXIEIAEEKGLSDMEVIHE--LATFIA---AGHDTVPYTLLYTLM 472
G D SG + +D +++A+E+ E ++ L T I AG TV T+ YTL+
Sbjct: 257 GNLDASGPARDLVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLL 316
Query: 471 CVGSHPPVQQRIYEELQQVLGSDDV-TKQNLSSLVYLEATIKETMRLYPIAPV-VSRVTD 298
+ +P VQ+ + EEL + LG+ + + + L Y +A + E RL + P+ + R
Sbjct: 317 LLMKYPHVQKWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLM 376
Query: 297 CDVKLRNSTIPSGASV 250
+ R T+P G V
Sbjct: 377 RTTRFRGYTLPQGTEV 392
Score = 31.5 bits (68), Expect = 2.8
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 2/61 (3%)
Frame = -2
Query: 236 HHPVWGSDVEHFKPERWLDPTTL--PENAFAGFSTGKRNCIGKTFAMMSMKTTLAHLLRQ 63
H P E F P+R+LD AF FS GKR C+G+ A + +L+
Sbjct: 401 HDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQA 460
Query: 62 Y 60
+
Sbjct: 461 F 461
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,329,991
Number of Sequences: 237096
Number of extensions: 2040662
Number of successful extensions: 6599
Number of sequences better than 10.0: 430
Number of HSP's better than 10.0 without gapping: 5646
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6349
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7535049140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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