Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmmt12c13
(618 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 147 3e-35
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 147 3e-35
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 147 3e-35
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 147 3e-35
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 138 2e-32
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 137 3e-32
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 137 3e-32
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 137 3e-32
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 137 3e-32
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 133 5e-31
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 125 1e-28
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 92 2e-18
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 92 2e-18
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 92 2e-18
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 92 2e-18
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 91 2e-18
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 91 2e-18
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 91 2e-18
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 84 4e-16
BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein. 69 1e-11
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 68 2e-11
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 68 2e-11
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 68 2e-11
BC151241-1|AAI51242.1| 1718|Homo sapiens MON2 protein protein. 31 4.3
AK092646-1|BAC03935.1| 586|Homo sapiens protein ( Homo sapiens ... 31 4.3
AB028963-1|BAA82992.3| 1736|Homo sapiens KIAA1040 protein protein. 31 4.3
AB017814-1|BAC11707.1| 1717|Homo sapiens SF21 protein protein. 31 4.3
U75276-1|AAB38876.1| 677|Homo sapiens TFIIB related factor hBRF... 29 9.9
BC086856-1|AAH86856.1| 650|Homo sapiens BRF1 protein protein. 29 9.9
BC071637-1|AAH71637.1| 486|Homo sapiens BRF1 protein protein. 29 9.9
AJ297407-1|CAC04513.1| 473|Homo sapiens transcription factor II... 29 9.9
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 147 bits (356), Expect = 3e-35
Identities = 77/188 (40%), Positives = 111/188 (59%), Gaps = 1/188 (0%)
Frame = -3
Query: 586 SVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKDPS 407
S LP FT+EE IR T D + +N Y SR+V+ P + P + D + A E+DPS
Sbjct: 1184 SRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLN----PPSYEDDQEMAEEEDPS 1239
Query: 406 WVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGIS-TGPGLDDRMRVEYYRDHLK 230
W + ++ P R + W+KE+YGD+ ITENG+ T P +D R+ Y++ ++
Sbjct: 1240 WPS--TAMNRAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPNTEDTDRIFYHKTYIN 1297
Query: 229 ELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKS 50
E L A DG+++ G+ AW+LMDNFEW +G KFGLY V+F + R RT RASA YY
Sbjct: 1298 EALKAYRLDGIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTE 1357
Query: 49 IIDTHSIP 26
+I + +P
Sbjct: 1358 VITNNGMP 1365
Score = 145 bits (352), Expect = 1e-34
Identities = 76/193 (39%), Positives = 107/193 (55%), Gaps = 2/193 (1%)
Frame = -3
Query: 598 GFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFE 419
G NKS LP FT+ E I GTYD++G N YT+ L +I ++ D A
Sbjct: 1654 GLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA----DRGVASI 1709
Query: 418 KDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTGP--GLDDRMRVEYY 245
D SW S W +TP FR + WLKE+Y D +TENG+S L+D R+ Y
Sbjct: 1710 ADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYL 1769
Query: 244 RDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASA 65
R ++ E L A+ +D V++ G+T W+ MDNFEW G +FGL+ VN++ P R P+ASA
Sbjct: 1770 RTYINEALKAV-QDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASA 1828
Query: 64 HYYKSIIDTHSIP 26
+Y S++ + P
Sbjct: 1829 KFYASVVRCNGFP 1841
Score = 113 bits (272), Expect = 5e-25
Identities = 63/185 (34%), Positives = 101/185 (54%), Gaps = 5/185 (2%)
Frame = -3
Query: 580 LPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKDPSWV 401
LP FT+ E L++G+ D+ G++ YTSRL+ A I ++ G + + W
Sbjct: 663 LPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGG----FSQHVNHVWP 718
Query: 400 AGYSSWFYVTPEYFRPQIMWLKEKY--GDLKFLITENGISTGPG---LDDRMRVEYYRDH 236
SSW V P R + ++ +Y G + + NG+ G DD +RV+Y+ +
Sbjct: 719 QTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQY 778
Query: 235 LKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYY 56
+ E+L AI ED V+V + A +L+D FE G +FGL+ VNF+ ++RTPR SA+++
Sbjct: 779 INEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFF 838
Query: 55 KSIID 41
SII+
Sbjct: 839 TSIIE 843
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 147 bits (356), Expect = 3e-35
Identities = 77/188 (40%), Positives = 111/188 (59%), Gaps = 1/188 (0%)
Frame = -3
Query: 586 SVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKDPS 407
S LP FT+EE IR T D + +N Y SR+V+ P + P + D + A E+DPS
Sbjct: 1184 SRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLN----PPSYEDDQEMAEEEDPS 1239
Query: 406 WVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGIS-TGPGLDDRMRVEYYRDHLK 230
W + ++ P R + W+KE+YGD+ ITENG+ T P +D R+ Y++ ++
Sbjct: 1240 WPS--TAMNRAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPNTEDTDRIFYHKTYIN 1297
Query: 229 ELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKS 50
E L A DG+++ G+ AW+LMDNFEW +G KFGLY V+F + R RT RASA YY
Sbjct: 1298 EALKAYRLDGIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTE 1357
Query: 49 IIDTHSIP 26
+I + +P
Sbjct: 1358 VITNNGMP 1365
Score = 145 bits (352), Expect = 1e-34
Identities = 76/193 (39%), Positives = 107/193 (55%), Gaps = 2/193 (1%)
Frame = -3
Query: 598 GFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFE 419
G NKS LP FT+ E I GTYD++G N YT+ L +I ++ D A
Sbjct: 1654 GLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA----DRGVASI 1709
Query: 418 KDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTGP--GLDDRMRVEYY 245
D SW S W +TP FR + WLKE+Y D +TENG+S L+D R+ Y
Sbjct: 1710 ADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYL 1769
Query: 244 RDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASA 65
R ++ E L A+ +D V++ G+T W+ MDNFEW G +FGL+ VN++ P R P+ASA
Sbjct: 1770 RTYINEALKAV-QDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASA 1828
Query: 64 HYYKSIIDTHSIP 26
+Y S++ + P
Sbjct: 1829 KFYASVVRCNGFP 1841
Score = 113 bits (272), Expect = 5e-25
Identities = 63/185 (34%), Positives = 101/185 (54%), Gaps = 5/185 (2%)
Frame = -3
Query: 580 LPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKDPSWV 401
LP FT+ E L++G+ D+ G++ YTSRL+ A I ++ G + + W
Sbjct: 663 LPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGG----FSQHVNHVWP 718
Query: 400 AGYSSWFYVTPEYFRPQIMWLKEKY--GDLKFLITENGISTGPG---LDDRMRVEYYRDH 236
SSW V P R + ++ +Y G + + NG+ G DD +RV+Y+ +
Sbjct: 719 QTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQY 778
Query: 235 LKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYY 56
+ E+L AI ED V+V + A +L+D FE G +FGL+ VNF+ ++RTPR SA+++
Sbjct: 779 INEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFF 838
Query: 55 KSIID 41
SII+
Sbjct: 839 TSIIE 843
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 147 bits (356), Expect = 3e-35
Identities = 77/188 (40%), Positives = 111/188 (59%), Gaps = 1/188 (0%)
Frame = -3
Query: 586 SVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKDPS 407
S LP FT+EE IR T D + +N Y SR+V+ P + P + D + A E+DPS
Sbjct: 616 SRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLN----PPSYEDDQEMAEEEDPS 671
Query: 406 WVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGIS-TGPGLDDRMRVEYYRDHLK 230
W + ++ P R + W+KE+YGD+ ITENG+ T P +D R+ Y++ ++
Sbjct: 672 WPS--TAMNRAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPNTEDTDRIFYHKTYIN 729
Query: 229 ELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKS 50
E L A DG+++ G+ AW+LMDNFEW +G KFGLY V+F + R RT RASA YY
Sbjct: 730 EALKAYRLDGIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTE 789
Query: 49 IIDTHSIP 26
+I + +P
Sbjct: 790 VITNNGMP 797
Score = 113 bits (272), Expect = 5e-25
Identities = 63/185 (34%), Positives = 101/185 (54%), Gaps = 5/185 (2%)
Frame = -3
Query: 580 LPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKDPSWV 401
LP FT+ E L++G+ D+ G++ YTSRL+ A I ++ G + + W
Sbjct: 95 LPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGG----FSQHVNHVWP 150
Query: 400 AGYSSWFYVTPEYFRPQIMWLKEKY--GDLKFLITENGISTGPG---LDDRMRVEYYRDH 236
SSW V P R + ++ +Y G + + NG+ G DD +RV+Y+ +
Sbjct: 151 QTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQY 210
Query: 235 LKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYY 56
+ E+L AI ED V+V + A +L+D FE G +FGL+ VNF+ ++RTPR SA+++
Sbjct: 211 INEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFF 270
Query: 55 KSIID 41
SII+
Sbjct: 271 TSIIE 275
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 147 bits (356), Expect = 3e-35
Identities = 77/188 (40%), Positives = 111/188 (59%), Gaps = 1/188 (0%)
Frame = -3
Query: 586 SVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKDPS 407
S LP FT+EE IR T D + +N Y SR+V+ P + P + D + A E+DPS
Sbjct: 1184 SRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLN----PPSYEDDQEMAEEEDPS 1239
Query: 406 WVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGIS-TGPGLDDRMRVEYYRDHLK 230
W + ++ P R + W+KE+YGD+ ITENG+ T P +D R+ Y++ ++
Sbjct: 1240 WPS--TAMNRAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPNTEDTDRIFYHKTYIN 1297
Query: 229 ELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKS 50
E L A DG+++ G+ AW+LMDNFEW +G KFGLY V+F + R RT RASA YY
Sbjct: 1298 EALKAYRLDGIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTE 1357
Query: 49 IIDTHSIP 26
+I + +P
Sbjct: 1358 VITNNGMP 1365
Score = 145 bits (352), Expect = 1e-34
Identities = 76/193 (39%), Positives = 107/193 (55%), Gaps = 2/193 (1%)
Frame = -3
Query: 598 GFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFE 419
G NKS LP FT+ E I GTYD++G N YT+ L +I ++ D A
Sbjct: 1654 GLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA----DRGVASI 1709
Query: 418 KDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTGP--GLDDRMRVEYY 245
D SW S W +TP FR + WLKE+Y D +TENG+S L+D R+ Y
Sbjct: 1710 ADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYL 1769
Query: 244 RDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASA 65
R ++ E L A+ +D V++ G+T W+ MDNFEW G +FGL+ VN++ P R P+ASA
Sbjct: 1770 RTYINEALKAV-QDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASA 1828
Query: 64 HYYKSIIDTHSIP 26
+Y S++ + P
Sbjct: 1829 KFYASVVRCNGFP 1841
Score = 113 bits (272), Expect = 5e-25
Identities = 63/185 (34%), Positives = 101/185 (54%), Gaps = 5/185 (2%)
Frame = -3
Query: 580 LPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKDPSWV 401
LP FT+ E L++G+ D+ G++ YTSRL+ A I ++ G + + W
Sbjct: 663 LPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGG----FSQHVNHVWP 718
Query: 400 AGYSSWFYVTPEYFRPQIMWLKEKY--GDLKFLITENGISTGPG---LDDRMRVEYYRDH 236
SSW V P R + ++ +Y G + + NG+ G DD +RV+Y+ +
Sbjct: 719 QTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQY 778
Query: 235 LKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYY 56
+ E+L AI ED V+V + A +L+D FE G +FGL+ VNF+ ++RTPR SA+++
Sbjct: 779 INEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFF 838
Query: 55 KSIID 41
SII+
Sbjct: 839 TSIIE 843
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 138 bits (333), Expect = 2e-32
Identities = 75/199 (37%), Positives = 110/199 (55%), Gaps = 4/199 (2%)
Frame = -3
Query: 613 VGKRKGFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVR--KARPGESIGAWPMNGAP 440
+ +++G+ S LP FT+EE +I+GT D++ + +YT+RL++ + + GE +
Sbjct: 275 MSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGE------LGTLQ 328
Query: 439 DFDAAFEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGI--STGPGLDD 266
D + F DPSW W YV P + ++K+ Y + ITENG S LDD
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 265 RMRVEYYRDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRT 86
R EY+R +EL AI D VN+ + AW+L+DNFEWN G S+FGL+ V+F P R
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 85 RTPRASAHYYKSIIDTHSI 29
R P SA Y II + +
Sbjct: 447 RVPYTSAKEYAKIIRNNGL 465
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 137 bits (331), Expect = 3e-32
Identities = 75/199 (37%), Positives = 110/199 (55%), Gaps = 4/199 (2%)
Frame = -3
Query: 613 VGKRKGFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVR--KARPGESIGAWPMNGAP 440
+ +++G+ S LP FT+EE +I+GT D++ + +YT+RL++ + + GE +
Sbjct: 275 MSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGE------LGILQ 328
Query: 439 DFDAAFEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGI--STGPGLDD 266
D + F DPSW W YV P + ++K+ Y + ITENG S LDD
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 265 RMRVEYYRDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRT 86
R EY+R +EL AI D VN+ + AW+L+DNFEWN G S+FGL+ V+F P R
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 85 RTPRASAHYYKSIIDTHSI 29
R P SA Y II + +
Sbjct: 447 RVPYTSAKEYAKIIRNNGL 465
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 137 bits (331), Expect = 3e-32
Identities = 75/199 (37%), Positives = 110/199 (55%), Gaps = 4/199 (2%)
Frame = -3
Query: 613 VGKRKGFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVR--KARPGESIGAWPMNGAP 440
+ +++G+ S LP FT+EE +I+GT D++ + +YT+RL++ + + GE +
Sbjct: 275 MSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGE------LGILQ 328
Query: 439 DFDAAFEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGI--STGPGLDD 266
D + F DPSW W YV P + ++K+ Y + ITENG S LDD
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 265 RMRVEYYRDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRT 86
R EY+R +EL AI D VN+ + AW+L+DNFEWN G S+FGL+ V+F P R
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 85 RTPRASAHYYKSIIDTHSI 29
R P SA Y II + +
Sbjct: 447 RVPYTSAKEYAKIIRNNGL 465
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 137 bits (331), Expect = 3e-32
Identities = 75/199 (37%), Positives = 110/199 (55%), Gaps = 4/199 (2%)
Frame = -3
Query: 613 VGKRKGFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVR--KARPGESIGAWPMNGAP 440
+ +++G+ S LP FT+EE +I+GT D++ + +YT+RL++ + + GE +
Sbjct: 275 MSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGE------LGILQ 328
Query: 439 DFDAAFEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGI--STGPGLDD 266
D + F DPSW W YV P + ++K+ Y + ITENG S LDD
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 265 RMRVEYYRDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRT 86
R EY+R +EL AI D VN+ + AW+L+DNFEWN G S+FGL+ V+F P R
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 85 RTPRASAHYYKSIIDTHSI 29
R P SA Y II + +
Sbjct: 447 RVPYTSAKEYAKIIRNNGL 465
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 137 bits (331), Expect = 3e-32
Identities = 75/199 (37%), Positives = 110/199 (55%), Gaps = 4/199 (2%)
Frame = -3
Query: 613 VGKRKGFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVR--KARPGESIGAWPMNGAP 440
+ +++G+ S LP FT+EE +I+GT D++ + +YT+RL++ + + GE +
Sbjct: 275 MSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQENKKGE------LGILQ 328
Query: 439 DFDAAFEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGI--STGPGLDD 266
D + F DPSW W YV P + ++K+ Y + ITENG S LDD
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 265 RMRVEYYRDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRT 86
R EY+R +EL AI D VN+ + AW+L+DNFEWN G S+FGL+ V+F P R
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 85 RTPRASAHYYKSIIDTHSI 29
R P SA Y II + +
Sbjct: 447 RVPYTSAKEYAKIIRNNGL 465
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 133 bits (321), Expect = 5e-31
Identities = 74/199 (37%), Positives = 109/199 (54%), Gaps = 4/199 (2%)
Frame = -3
Query: 613 VGKRKGFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVR--KARPGESIGAWPMNGAP 440
+ +++G+ S LP FT+EE +I+GT D++ + + T+RL++ + + GE +
Sbjct: 275 MSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYCTTRLIKYQENKRGE------LGILQ 328
Query: 439 DFDAAFEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGI--STGPGLDD 266
D + F DPSW W YV P + ++K+ Y + ITENG S LDD
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 265 RMRVEYYRDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRT 86
R EY+R +EL AI D VN+ + AW+L+DNFEWN G S+FGL+ V+F P R
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 85 RTPRASAHYYKSIIDTHSI 29
R P SA Y II + +
Sbjct: 447 RVPYTSAKEYAKIIRNNGL 465
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 125 bits (302), Expect = 1e-28
Identities = 67/195 (34%), Positives = 100/195 (51%), Gaps = 3/195 (1%)
Frame = -3
Query: 601 KGFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAF 422
+G S LP F+ +E I+GT D+ G+ +T+R + + G N D D
Sbjct: 314 QGLEMSRLPVFSLQEKSYIKGTSDFLGLGHFTTRYITERNYPSRQGPSYQN---DRDLIE 370
Query: 421 EKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTG---PGLDDRMRVE 251
DP+W S W Y P FR + + + +YGD + ENG S L D R++
Sbjct: 371 LVDPNWPDLGSKWLYSVPWGFRRLLNFAQTQYGDPPIYVMENGASQKFHCTQLCDEWRIQ 430
Query: 250 YYRDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRA 71
Y + ++ E+L AI +DG N+ G+T+W+L+D FEW G ++G Y V F + R P+A
Sbjct: 431 YLKGYINEMLKAI-KDGANIKGYTSWSLLDKFEWEKGYSDRYGFYYVEFNDRNKPRYPKA 489
Query: 70 SAHYYKSIIDTHSIP 26
S YYK II + P
Sbjct: 490 SVQYYKKIIIANGFP 504
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 91.9 bits (218), Expect = 2e-18
Identities = 63/190 (33%), Positives = 97/190 (51%), Gaps = 1/190 (0%)
Frame = -3
Query: 592 NKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKD 413
N +LP FT++E LI+GT+D+ ++ YT+ LV + P+ + D
Sbjct: 509 NNFLLPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKED------PIKYNDYLEVQEMTD 562
Query: 412 PSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTG-PGLDDRMRVEYYRDH 236
+W+ S V P R + WLK KYGDL I NGI G DD++RV Y +++
Sbjct: 563 ITWLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAEDDQLRVYYMQNY 621
Query: 235 LKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYY 56
+ E L A DG+N+ G+ A + +ND +FGLY + + Q P+AS +Y
Sbjct: 622 INEALKAHILDGINLCGYFA------YSFNDRTAPRFGLY--RYAADQ--FEPKASMKHY 671
Query: 55 KSIIDTHSIP 26
+ IID++ P
Sbjct: 672 RKIIDSNGFP 681
Score = 83.8 bits (198), Expect = 4e-16
Identities = 40/113 (35%), Positives = 65/113 (57%), Gaps = 2/113 (1%)
Frame = -3
Query: 358 RPQIMWLKEKYGDLKFLITENG--ISTGPGLDDRMRVEYYRDHLKELLLAIHEDGVNVVG 185
R + W+ ++ + I ENG +S DD + Y + + E L AI DGV+V+G
Sbjct: 122 RQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIG 181
Query: 184 FTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKSIIDTHSIP 26
+TAW+LMD FEW+ G + GL+ V+F S + P++SA +Y+ +I+ + P
Sbjct: 182 YTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFP 234
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 91.9 bits (218), Expect = 2e-18
Identities = 63/190 (33%), Positives = 97/190 (51%), Gaps = 1/190 (0%)
Frame = -3
Query: 592 NKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKD 413
N +LP FT++E LI+GT+D+ ++ YT+ LV + P+ + D
Sbjct: 782 NNFLLPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKED------PIKYNDYLEVQEMTD 835
Query: 412 PSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTG-PGLDDRMRVEYYRDH 236
+W+ S V P R + WLK KYGDL I NGI G DD++RV Y +++
Sbjct: 836 ITWLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAEDDQLRVYYMQNY 894
Query: 235 LKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYY 56
+ E L A DG+N+ G+ A + +ND +FGLY + + Q P+AS +Y
Sbjct: 895 INEALKAHILDGINLCGYFA------YSFNDRTAPRFGLY--RYAADQ--FEPKASMKHY 944
Query: 55 KSIIDTHSIP 26
+ IID++ P
Sbjct: 945 RKIIDSNGFP 954
Score = 83.8 bits (198), Expect = 4e-16
Identities = 40/113 (35%), Positives = 65/113 (57%), Gaps = 2/113 (1%)
Frame = -3
Query: 358 RPQIMWLKEKYGDLKFLITENG--ISTGPGLDDRMRVEYYRDHLKELLLAIHEDGVNVVG 185
R + W+ ++ + I ENG +S DD + Y + + E L AI DGV+V+G
Sbjct: 395 RQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIG 454
Query: 184 FTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKSIIDTHSIP 26
+TAW+LMD FEW+ G + GL+ V+F S + P++SA +Y+ +I+ + P
Sbjct: 455 YTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFP 507
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) protein.
Length = 1012
Score = 91.9 bits (218), Expect = 2e-18
Identities = 63/190 (33%), Positives = 97/190 (51%), Gaps = 1/190 (0%)
Frame = -3
Query: 592 NKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKD 413
N +LP FT++E LI+GT+D+ ++ YT+ LV + P+ + D
Sbjct: 782 NNFLLPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKED------PIKYNDYLEVQEMTD 835
Query: 412 PSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTG-PGLDDRMRVEYYRDH 236
+W+ S V P R + WLK KYGDL I NGI G DD++RV Y +++
Sbjct: 836 ITWLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAEDDQLRVYYMQNY 894
Query: 235 LKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYY 56
+ E L A DG+N+ G+ A + +ND +FGLY + + Q P+AS +Y
Sbjct: 895 INEALKAHILDGINLCGYFA------YSFNDRTAPRFGLY--RYAADQ--FEPKASMKHY 944
Query: 55 KSIIDTHSIP 26
+ IID++ P
Sbjct: 945 RKIIDSNGFP 954
Score = 83.8 bits (198), Expect = 4e-16
Identities = 40/113 (35%), Positives = 65/113 (57%), Gaps = 2/113 (1%)
Frame = -3
Query: 358 RPQIMWLKEKYGDLKFLITENG--ISTGPGLDDRMRVEYYRDHLKELLLAIHEDGVNVVG 185
R + W+ ++ + I ENG +S DD + Y + + E L AI DGV+V+G
Sbjct: 395 RQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIG 454
Query: 184 FTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKSIIDTHSIP 26
+TAW+LMD FEW+ G + GL+ V+F S + P++SA +Y+ +I+ + P
Sbjct: 455 YTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFP 507
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 91.9 bits (218), Expect = 2e-18
Identities = 63/190 (33%), Positives = 97/190 (51%), Gaps = 1/190 (0%)
Frame = -3
Query: 592 NKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAAFEKD 413
N +LP FT++E LI+GT+D+ ++ YT+ LV + P+ + D
Sbjct: 782 NNFLLPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKED------PIKYNDYLEVQEMTD 835
Query: 412 PSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTG-PGLDDRMRVEYYRDH 236
+W+ S V P R + WLK KYGDL I NGI G DD++RV Y +++
Sbjct: 836 ITWLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAEDDQLRVYYMQNY 894
Query: 235 LKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYY 56
+ E L A DG+N+ G+ A + +ND +FGLY + + Q P+AS +Y
Sbjct: 895 INEALKAHILDGINLCGYFA------YSFNDRTAPRFGLY--RYAADQ--FEPKASMKHY 944
Query: 55 KSIIDTHSIP 26
+ IID++ P
Sbjct: 945 RKIIDSNGFP 954
Score = 83.8 bits (198), Expect = 4e-16
Identities = 40/113 (35%), Positives = 65/113 (57%), Gaps = 2/113 (1%)
Frame = -3
Query: 358 RPQIMWLKEKYGDLKFLITENG--ISTGPGLDDRMRVEYYRDHLKELLLAIHEDGVNVVG 185
R + W+ ++ + I ENG +S DD + Y + + E L AI DGV+V+G
Sbjct: 395 RQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIG 454
Query: 184 FTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKSIIDTHSIP 26
+TAW+LMD FEW+ G + GL+ V+F S + P++SA +Y+ +I+ + P
Sbjct: 455 YTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFP 507
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 91.5 bits (217), Expect = 2e-18
Identities = 43/107 (40%), Positives = 65/107 (60%), Gaps = 2/107 (1%)
Frame = -3
Query: 358 RPQIMWLKEKYGDLKFLITENGISTGPGL--DDRMRVEYYRDHLKELLLAIHEDGVNVVG 185
R + W+K +Y + + LI ENG T + +D + ++ L ++L AI D + V G
Sbjct: 397 REALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFG 456
Query: 184 FTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKSII 44
+TAW+L+D FEW D + GL+ V+F S Q+ R P++SAHYYK II
Sbjct: 457 YTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQII 503
Score = 69.3 bits (162), Expect = 1e-11
Identities = 52/193 (26%), Positives = 90/193 (46%)
Frame = -3
Query: 604 RKGFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAA 425
R+G + S LP T+ E L++GT D+ +N +T+R V + S D D
Sbjct: 795 RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGS------RYDSDRDIQ 848
Query: 424 FEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTGPGLDDRMRVEYY 245
F +D + ++ + V P R + W++ YGD+ IT +GI DDR+R Y
Sbjct: 849 FLQDITRLSSPTR-LAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDDRLRKYYL 907
Query: 244 RDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASA 65
+L+E+L A D V + G+ A+ L + + +FG + +F + ++S
Sbjct: 908 GKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDFKA-------KSSI 955
Query: 64 HYYKSIIDTHSIP 26
+Y +I + P
Sbjct: 956 QFYNKVISSRGFP 968
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 91.5 bits (217), Expect = 2e-18
Identities = 43/107 (40%), Positives = 65/107 (60%), Gaps = 2/107 (1%)
Frame = -3
Query: 358 RPQIMWLKEKYGDLKFLITENGISTGPGL--DDRMRVEYYRDHLKELLLAIHEDGVNVVG 185
R + W+K +Y + + LI ENG T + +D + ++ L ++L AI D + V G
Sbjct: 397 REALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFG 456
Query: 184 FTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKSII 44
+TAW+L+D FEW D + GL+ V+F S Q+ R P++SAHYYK II
Sbjct: 457 YTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQII 503
Score = 69.3 bits (162), Expect = 1e-11
Identities = 52/193 (26%), Positives = 90/193 (46%)
Frame = -3
Query: 604 RKGFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAA 425
R+G + S LP T+ E L++GT D+ +N +T+R V + S D D
Sbjct: 795 RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGS------RYDSDRDIQ 848
Query: 424 FEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTGPGLDDRMRVEYY 245
F +D + ++ + V P R + W++ YGD+ IT +GI DDR+R Y
Sbjct: 849 FLQDITRLSSPTR-LAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDDRLRKYYL 907
Query: 244 RDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASA 65
+L+E+L A D V + G+ A+ L + + +FG + +F + ++S
Sbjct: 908 GKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDFKA-------KSSI 955
Query: 64 HYYKSIIDTHSIP 26
+Y +I + P
Sbjct: 956 QFYNKVISSRGFP 968
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 91.5 bits (217), Expect = 2e-18
Identities = 43/107 (40%), Positives = 65/107 (60%), Gaps = 2/107 (1%)
Frame = -3
Query: 358 RPQIMWLKEKYGDLKFLITENGISTGPGL--DDRMRVEYYRDHLKELLLAIHEDGVNVVG 185
R + W+K +Y + + LI ENG T + +D + ++ L ++L AI D + V G
Sbjct: 397 REALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFG 456
Query: 184 FTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKSII 44
+TAW+L+D FEW D + GL+ V+F S Q+ R P++SAHYYK II
Sbjct: 457 YTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQII 503
Score = 69.3 bits (162), Expect = 1e-11
Identities = 52/193 (26%), Positives = 90/193 (46%)
Frame = -3
Query: 604 RKGFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAA 425
R+G + S LP T+ E L++GT D+ +N +T+R V + S D D
Sbjct: 795 RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGS------RYDSDRDIQ 848
Query: 424 FEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTGPGLDDRMRVEYY 245
F +D + ++ + V P R + W++ YGD+ IT +GI DDR+R Y
Sbjct: 849 FLQDITRLSSPTR-LAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDDRLRKYYL 907
Query: 244 RDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASA 65
+L+E+L A D V + G+ A+ L + + +FG + +F + ++S
Sbjct: 908 GKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDFKA-------KSSI 955
Query: 64 HYYKSIIDTHSIP 26
+Y +I + P
Sbjct: 956 QFYNKVISSRGFP 968
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 83.8 bits (198), Expect = 4e-16
Identities = 40/113 (35%), Positives = 65/113 (57%), Gaps = 2/113 (1%)
Frame = -3
Query: 358 RPQIMWLKEKYGDLKFLITENG--ISTGPGLDDRMRVEYYRDHLKELLLAIHEDGVNVVG 185
R + W+ ++ + I ENG +S DD + Y + + E L AI DGV+V+G
Sbjct: 395 RQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIG 454
Query: 184 FTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKSIIDTHSIP 26
+TAW+LMD FEW+ G + GL+ V+F S + P++SA +Y+ +I+ + P
Sbjct: 455 YTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFP 507
>BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein.
Length = 305
Score = 69.3 bits (162), Expect = 1e-11
Identities = 52/193 (26%), Positives = 90/193 (46%)
Frame = -3
Query: 604 RKGFNKSVLPPFTKEEIDLIRGTYDYYGMNFYTSRLVRKARPGESIGAWPMNGAPDFDAA 425
R+G + S LP T+ E L++GT D+ +N +T+R V + S D D
Sbjct: 56 RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGS------RYDSDRDIQ 109
Query: 424 FEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDLKFLITENGISTGPGLDDRMRVEYY 245
F +D + ++ + V P R + W++ YGD+ IT +GI DDR+R Y
Sbjct: 110 FLQDITRLSSPTR-LAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDDRLRKYYL 168
Query: 244 RDHLKELLLAIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASA 65
+L+E+L A D V + G+ A+ L + + +FG + +F + ++S
Sbjct: 169 GKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFTSDFKA-------KSSI 216
Query: 64 HYYKSIIDTHSIP 26
+Y +I + P
Sbjct: 217 QFYNKVISSRGFP 229
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 68.1 bits (159), Expect = 2e-11
Identities = 30/63 (47%), Positives = 39/63 (61%)
Frame = -3
Query: 217 AIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKSIIDT 38
AI D VN+ + AW+L+DNFEWN G S+FGL+ V+F P R R P SA Y II
Sbjct: 96 AIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 155
Query: 37 HSI 29
+ +
Sbjct: 156 NGL 158
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 68.1 bits (159), Expect = 2e-11
Identities = 30/63 (47%), Positives = 39/63 (61%)
Frame = -3
Query: 217 AIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKSIIDT 38
AI D VN+ + AW+L+DNFEWN G S+FGL+ V+F P R R P SA Y II
Sbjct: 96 AIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 155
Query: 37 HSI 29
+ +
Sbjct: 156 NGL 158
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 68.1 bits (159), Expect = 2e-11
Identities = 30/63 (47%), Positives = 39/63 (61%)
Frame = -3
Query: 217 AIHEDGVNVVGFTAWTLMDNFEWNDGLGSKFGLYEVNFTSPQRTRTPRASAHYYKSIIDT 38
AI D VN+ + AW+L+DNFEWN G S+FGL+ V+F P R R P SA Y II
Sbjct: 96 AIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 155
Query: 37 HSI 29
+ +
Sbjct: 156 NGL 158
>BC151241-1|AAI51242.1| 1718|Homo sapiens MON2 protein protein.
Length = 1718
Score = 30.7 bits (66), Expect = 4.3
Identities = 22/96 (22%), Positives = 42/96 (43%)
Frame = -3
Query: 496 VRKARPGESIGAWPMNGAPDFDAAFEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDL 317
VR GE +G + + P E W A +++W+ + E +P I + K +
Sbjct: 1211 VRTDSIGEKLGRYSSSEPPIVTDELEDLNLWWAAWNTWYRIGSESTKPPITFDKLTFIPS 1270
Query: 316 KFLITENGISTGPGLDDRMRVEYYRDHLKELLLAIH 209
+ +T I P L ++ + D L++L + +H
Sbjct: 1271 QPFLTAL-IQIFPALYQHIKTGFNMDDLQKLGVILH 1305
>AK092646-1|BAC03935.1| 586|Homo sapiens protein ( Homo sapiens
cDNA FLJ35327 fis, clone PROST2013032. ).
Length = 586
Score = 30.7 bits (66), Expect = 4.3
Identities = 22/96 (22%), Positives = 42/96 (43%)
Frame = -3
Query: 496 VRKARPGESIGAWPMNGAPDFDAAFEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDL 317
VR GE +G + + P E W A +++W+ + E +P I + K +
Sbjct: 85 VRTDSIGEKLGRYSSSEPPIVTDELEDLNLWWAAWNTWYRIGSESTKPPITFDKLTFIPS 144
Query: 316 KFLITENGISTGPGLDDRMRVEYYRDHLKELLLAIH 209
+ +T I P L ++ + D L++L + +H
Sbjct: 145 QPFLTAL-IQIFPALYQHIKTGFNMDDLQKLGVILH 179
>AB028963-1|BAA82992.3| 1736|Homo sapiens KIAA1040 protein protein.
Length = 1736
Score = 30.7 bits (66), Expect = 4.3
Identities = 22/96 (22%), Positives = 42/96 (43%)
Frame = -3
Query: 496 VRKARPGESIGAWPMNGAPDFDAAFEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDL 317
VR GE +G + + P E W A +++W+ + E +P I + K +
Sbjct: 1229 VRTDSIGEKLGRYSSSEPPIVTDELEDLNLWWAAWNTWYRIGSESTKPPITFDKLTFIPS 1288
Query: 316 KFLITENGISTGPGLDDRMRVEYYRDHLKELLLAIH 209
+ +T I P L ++ + D L++L + +H
Sbjct: 1289 QPFLTAL-IQIFPALYQHIKTGFNMDDLQKLGVILH 1323
>AB017814-1|BAC11707.1| 1717|Homo sapiens SF21 protein protein.
Length = 1717
Score = 30.7 bits (66), Expect = 4.3
Identities = 22/96 (22%), Positives = 42/96 (43%)
Frame = -3
Query: 496 VRKARPGESIGAWPMNGAPDFDAAFEKDPSWVAGYSSWFYVTPEYFRPQIMWLKEKYGDL 317
VR GE +G + + P E W A +++W+ + E +P I + K +
Sbjct: 1210 VRTDSIGEKLGRYSSSEPPIVTDELEDLNLWWAAWNTWYRIGSESTKPPITFDKLTFIPS 1269
Query: 316 KFLITENGISTGPGLDDRMRVEYYRDHLKELLLAIH 209
+ +T I P L ++ + D L++L + +H
Sbjct: 1270 QPFLTAL-IQIFPALYQHIKTGFNMDDLQKLGVILH 1304
>U75276-1|AAB38876.1| 677|Homo sapiens TFIIB related factor hBRF
protein.
Length = 677
Score = 29.5 bits (63), Expect = 9.9
Identities = 16/53 (30%), Positives = 27/53 (50%)
Frame = -1
Query: 537 HTTTTE*ISTRVVWCGRRGPANLSEPGQ*TEPLILTQPSRKIQAGSPAILAGS 379
H+ + +S R R G ++ G+ PL+ TQP++K+ G A+L S
Sbjct: 563 HSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGE-ALLPSS 614
>BC086856-1|AAH86856.1| 650|Homo sapiens BRF1 protein protein.
Length = 650
Score = 29.5 bits (63), Expect = 9.9
Identities = 16/53 (30%), Positives = 27/53 (50%)
Frame = -1
Query: 537 HTTTTE*ISTRVVWCGRRGPANLSEPGQ*TEPLILTQPSRKIQAGSPAILAGS 379
H+ + +S R R G ++ G+ PL+ TQP++K+ G A+L S
Sbjct: 536 HSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGE-ALLPSS 587
>BC071637-1|AAH71637.1| 486|Homo sapiens BRF1 protein protein.
Length = 486
Score = 29.5 bits (63), Expect = 9.9
Identities = 16/53 (30%), Positives = 27/53 (50%)
Frame = -1
Query: 537 HTTTTE*ISTRVVWCGRRGPANLSEPGQ*TEPLILTQPSRKIQAGSPAILAGS 379
H+ + +S R R G ++ G+ PL+ TQP++K+ G A+L S
Sbjct: 372 HSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGE-ALLPSS 423
>AJ297407-1|CAC04513.1| 473|Homo sapiens transcription factor II
B-related factor protein.
Length = 473
Score = 29.5 bits (63), Expect = 9.9
Identities = 16/53 (30%), Positives = 27/53 (50%)
Frame = -1
Query: 537 HTTTTE*ISTRVVWCGRRGPANLSEPGQ*TEPLILTQPSRKIQAGSPAILAGS 379
H+ + +S R R G ++ G+ PL+ TQP++K+ G A+L S
Sbjct: 359 HSASARKLSRRRTPASRSGADPVTSVGKRLRPLVSTQPAKKVATGE-ALLPSS 410
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,377,236
Number of Sequences: 237096
Number of extensions: 1971548
Number of successful extensions: 4424
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 4067
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4375
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6635341780
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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