Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= rbmmt10k21
(706 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 165 2e-40
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 164 2e-40
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 164 2e-40
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 157 4e-38
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 154 3e-37
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 147 3e-35
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 147 3e-35
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 147 3e-35
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 147 3e-35
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 146 5e-35
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 143 5e-34
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 100 1e-20
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 100 1e-20
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 100 1e-20
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 97 4e-20
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 97 4e-20
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 97 4e-20
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 97 4e-20
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 85 4e-20
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 77 5e-14
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 77 5e-14
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 77 5e-14
BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein. 75 2e-13
BC028696-1|AAH28696.1| 281|Homo sapiens RAB40C, member RAS onco... 30 9.3
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 165 bits (400), Expect = 2e-40
Identities = 86/232 (37%), Positives = 132/232 (56%), Gaps = 2/232 (0%)
Frame = -1
Query: 703 EADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIE 524
+ D E A ++ G FA+PI+ K G + +K + + S G N +R+ +FT E
Sbjct: 1611 QEDVEAARRYVQFMGGWFAHPIF-KNGDYSEVMKTRIRDRSLAAGLNKSRLPEFTESEKR 1669
Query: 523 FVKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIY-- 350
+ GTYDF+ NHYT+ V A N A F ++ GV +W S F +
Sbjct: 1670 RINGTYDFFGFNHYTT--VLAYNLNYATAISSFD--ADRGVASIADRSWPDSGSFWLKMT 1725
Query: 349 PPGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKI 170
P G RR LNWLK Y D P +TE G + LND RI +++ Y+NE L A+ +DK+
Sbjct: 1726 PFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAV-QDKV 1784
Query: 169 NVTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
++ GYTVWS MD++EW +G++ ++GL+ V++ P+ R P+ SAK+YA +++
Sbjct: 1785 DLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 157 bits (381), Expect = 4e-38
Identities = 88/232 (37%), Positives = 124/232 (53%)
Frame = -1
Query: 697 DSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFV 518
D E A+ ++ G FA+PI+ + G +P +K + S + +R+ FT EE F+
Sbjct: 1139 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 1197
Query: 517 KGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPGL 338
+ T D + LN Y S +V+ P P S + + P+W +A P G
Sbjct: 1198 RATADVFCLNTYYSRIVQHKTPRLN----PPSYEDDQEMAEEEDPSWPSTAMNRAAPWGT 1253
Query: 337 RRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVTG 158
RR LNW+K YGDIP ITE G D RI + K Y+NE L A D I++ G
Sbjct: 1254 RRLLNWIKEEYGDIPIYITENG-VGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRG 1312
Query: 157 YTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNRAL 2
Y WSLMD++EW +GYT K+GLY VDF + N+ RT R SA+YY ++I N +
Sbjct: 1313 YVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGM 1364
Score = 120 bits (288), Expect = 7e-27
Identities = 71/231 (30%), Positives = 118/231 (51%), Gaps = 3/231 (1%)
Frame = -1
Query: 697 DSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFV 518
D +E + G FA+P++ +G +P L+ + + + ++ +FT E + +
Sbjct: 616 DLRASERFLHFMLGWFAHPVFV-DGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLL 674
Query: 517 KGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPGL 338
KG+ DF L+HYTS ++ N + G VN T S+ + P G+
Sbjct: 675 KGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQHVNHVWPQT--SSSWIRVVPWGI 732
Query: 337 RRQLNWLKNRY--GDIPFMITETGYASYPFHGLNDDG-RINFIKDYLNEVLLAIYEDKIN 167
RR L ++ Y G +P + G L DD R+++ Y+NEVL AI ED ++
Sbjct: 733 RRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVD 792
Query: 166 VTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
V Y SL+D +E SGY+ ++GL+ V+F +K+RTPRKSA ++ +I+
Sbjct: 793 VRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIE 843
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 164 bits (399), Expect = 2e-40
Identities = 86/232 (37%), Positives = 132/232 (56%), Gaps = 2/232 (0%)
Frame = -1
Query: 703 EADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIE 524
+ D E A ++ G FA+PI+ K G + +K + + S G N +R+ +FT E
Sbjct: 1611 QEDVEAARRYVQFMGGWFAHPIF-KNGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKR 1669
Query: 523 FVKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIY-- 350
+ GTYDF+ NHYT+ V A N A F ++ GV +W S F +
Sbjct: 1670 RINGTYDFFGFNHYTT--VLAYNLNYATAISSFD--ADRGVASIADRSWPDSGSFWLKMT 1725
Query: 349 PPGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKI 170
P G RR LNWLK Y D P +TE G + LND RI +++ Y+NE L A+ +DK+
Sbjct: 1726 PFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAV-QDKV 1784
Query: 169 NVTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
++ GYTVWS MD++EW +G++ ++GL+ V++ P+ R P+ SAK+YA +++
Sbjct: 1785 DLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 157 bits (381), Expect = 4e-38
Identities = 88/232 (37%), Positives = 124/232 (53%)
Frame = -1
Query: 697 DSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFV 518
D E A+ ++ G FA+PI+ + G +P +K + S + +R+ FT EE F+
Sbjct: 1139 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 1197
Query: 517 KGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPGL 338
+ T D + LN Y S +V+ P P S + + P+W +A P G
Sbjct: 1198 RATADVFCLNTYYSRIVQHKTPRLN----PPSYEDDQEMAEEEDPSWPSTAMNRAAPWGT 1253
Query: 337 RRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVTG 158
RR LNW+K YGDIP ITE G D RI + K Y+NE L A D I++ G
Sbjct: 1254 RRLLNWIKEEYGDIPIYITENG-VGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRG 1312
Query: 157 YTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNRAL 2
Y WSLMD++EW +GYT K+GLY VDF + N+ RT R SA+YY ++I N +
Sbjct: 1313 YVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGM 1364
Score = 120 bits (288), Expect = 7e-27
Identities = 71/231 (30%), Positives = 118/231 (51%), Gaps = 3/231 (1%)
Frame = -1
Query: 697 DSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFV 518
D +E + G FA+P++ +G +P L+ + + + ++ +FT E + +
Sbjct: 616 DLRASERFLHFMLGWFAHPVFV-DGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLL 674
Query: 517 KGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPGL 338
KG+ DF L+HYTS ++ N + G VN T S+ + P G+
Sbjct: 675 KGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQHVNHVWPQT--SSSWIRVVPWGI 732
Query: 337 RRQLNWLKNRY--GDIPFMITETGYASYPFHGLNDDG-RINFIKDYLNEVLLAIYEDKIN 167
RR L ++ Y G +P + G L DD R+++ Y+NEVL AI ED ++
Sbjct: 733 RRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVD 792
Query: 166 VTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
V Y SL+D +E SGY+ ++GL+ V+F +K+RTPRKSA ++ +I+
Sbjct: 793 VRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIE 843
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 164 bits (399), Expect = 2e-40
Identities = 86/232 (37%), Positives = 132/232 (56%), Gaps = 2/232 (0%)
Frame = -1
Query: 703 EADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIE 524
+ D E A ++ G FA+PI+ K G + +K + + S G N +R+ +FT E
Sbjct: 1611 QEDVEAARRYVQFMGGWFAHPIF-KNGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKR 1669
Query: 523 FVKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIY-- 350
+ GTYDF+ NHYT+ V A N A F ++ GV +W S F +
Sbjct: 1670 RINGTYDFFGFNHYTT--VLAYNLNYATAISSFD--ADRGVASIADRSWPDSGSFWLKMT 1725
Query: 349 PPGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKI 170
P G RR LNWLK Y D P +TE G + LND RI +++ Y+NE L A+ +DK+
Sbjct: 1726 PFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAV-QDKV 1784
Query: 169 NVTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
++ GYTVWS MD++EW +G++ ++GL+ V++ P+ R P+ SAK+YA +++
Sbjct: 1785 DLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 157 bits (381), Expect = 4e-38
Identities = 88/232 (37%), Positives = 124/232 (53%)
Frame = -1
Query: 697 DSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFV 518
D E A+ ++ G FA+PI+ + G +P +K + S + +R+ FT EE F+
Sbjct: 1139 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 1197
Query: 517 KGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPGL 338
+ T D + LN Y S +V+ P P S + + P+W +A P G
Sbjct: 1198 RATADVFCLNTYYSRIVQHKTPRLN----PPSYEDDQEMAEEEDPSWPSTAMNRAAPWGT 1253
Query: 337 RRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVTG 158
RR LNW+K YGDIP ITE G D RI + K Y+NE L A D I++ G
Sbjct: 1254 RRLLNWIKEEYGDIPIYITENG-VGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRG 1312
Query: 157 YTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNRAL 2
Y WSLMD++EW +GYT K+GLY VDF + N+ RT R SA+YY ++I N +
Sbjct: 1313 YVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGM 1364
Score = 120 bits (288), Expect = 7e-27
Identities = 71/231 (30%), Positives = 118/231 (51%), Gaps = 3/231 (1%)
Frame = -1
Query: 697 DSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFV 518
D +E + G FA+P++ +G +P L+ + + + ++ +FT E + +
Sbjct: 616 DLRASERFLHFMLGWFAHPVFV-DGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLL 674
Query: 517 KGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPGL 338
KG+ DF L+HYTS ++ N + G VN T S+ + P G+
Sbjct: 675 KGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQHVNHVWPQT--SSSWIRVVPWGI 732
Query: 337 RRQLNWLKNRY--GDIPFMITETGYASYPFHGLNDDG-RINFIKDYLNEVLLAIYEDKIN 167
RR L ++ Y G +P + G L DD R+++ Y+NEVL AI ED ++
Sbjct: 733 RRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVD 792
Query: 166 VTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
V Y SL+D +E SGY+ ++GL+ V+F +K+RTPRKSA ++ +I+
Sbjct: 793 VRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIE 843
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 157 bits (381), Expect = 4e-38
Identities = 88/232 (37%), Positives = 124/232 (53%)
Frame = -1
Query: 697 DSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFV 518
D E A+ ++ G FA+PI+ + G +P +K + S + +R+ FT EE F+
Sbjct: 571 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 629
Query: 517 KGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPGL 338
+ T D + LN Y S +V+ P P S + + P+W +A P G
Sbjct: 630 RATADVFCLNTYYSRIVQHKTPRLN----PPSYEDDQEMAEEEDPSWPSTAMNRAAPWGT 685
Query: 337 RRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVTG 158
RR LNW+K YGDIP ITE G D RI + K Y+NE L A D I++ G
Sbjct: 686 RRLLNWIKEEYGDIPIYITENG-VGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRG 744
Query: 157 YTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNRAL 2
Y WSLMD++EW +GYT K+GLY VDF + N+ RT R SA+YY ++I N +
Sbjct: 745 YVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGM 796
Score = 120 bits (288), Expect = 7e-27
Identities = 71/231 (30%), Positives = 118/231 (51%), Gaps = 3/231 (1%)
Frame = -1
Query: 697 DSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFV 518
D +E + G FA+P++ +G +P L+ + + + ++ +FT E + +
Sbjct: 48 DLRASERFLHFMLGWFAHPVFV-DGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLL 106
Query: 517 KGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPGL 338
KG+ DF L+HYTS ++ N + G VN T S+ + P G+
Sbjct: 107 KGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQHVNHVWPQT--SSSWIRVVPWGI 164
Query: 337 RRQLNWLKNRY--GDIPFMITETGYASYPFHGLNDDG-RINFIKDYLNEVLLAIYEDKIN 167
RR L ++ Y G +P + G L DD R+++ Y+NEVL AI ED ++
Sbjct: 165 RRLLQFVSLEYTRGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVD 224
Query: 166 VTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
V Y SL+D +E SGY+ ++GL+ V+F +K+RTPRKSA ++ +I+
Sbjct: 225 VRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIE 275
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 154 bits (373), Expect = 3e-37
Identities = 88/231 (38%), Positives = 129/231 (55%), Gaps = 4/231 (1%)
Frame = -1
Query: 697 DSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFV 518
D E AE ++C G FA PIY+ G +P +K+ + S +G +R+ F+ +E ++
Sbjct: 275 DLEAAERYLQFCLGWFANPIYA--GDYPQVMKDYIGRKSAEQGLEMSRLPVFSLQEKSYI 332
Query: 517 KGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIY--PP 344
KGT DF L H+T+ + E N + P S ++ + P W +Y P
Sbjct: 333 KGTSDFLGLGHFTTRYIT--ERNYPSRQGP-SYQNDRDLIELVDPNWPDLGSKWLYSVPW 389
Query: 343 GLRRQLNWLKNRYGDIPFMITETGYASYPFH--GLNDDGRINFIKDYLNEVLLAIYEDKI 170
G RR LN+ + +YGD P + E G AS FH L D+ RI ++K Y+NE+L AI +D
Sbjct: 390 GFRRLLNFAQTQYGDPPIYVMENG-ASQKFHCTQLCDEWRIQYLKGYINEMLKAI-KDGA 447
Query: 169 NVTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLI 17
N+ GYT WSL+D +EWE GY+ +YG Y V+F NK R P+ S +YY +I
Sbjct: 448 NIKGYTSWSLLDKFEWEKGYSDRYGFYYVEFNDRNKPRYPKASVQYYKKII 498
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 147 bits (357), Expect = 3e-35
Identities = 77/233 (33%), Positives = 131/233 (56%)
Frame = -1
Query: 700 ADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEF 521
+D E A+ + FA PI+ +G +P +K+ + S +G+ ++R+ +FT EE +
Sbjct: 238 SDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKM 296
Query: 520 VKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPG 341
+KGT DF+A+ +YT+ ++K E + G+ +E + F P P+W+ + P G
Sbjct: 297 IKGTADFFAVQYYTTRLIKYQENKK--GELGILQDAE--IEFFPDPSWKNVDWIYVVPWG 352
Query: 340 LRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVT 161
+ + L ++K+ Y + ITE G+ L+D R + + E+ AI DK+N+
Sbjct: 353 VCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQ 412
Query: 160 GYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNRAL 2
Y WSL+D++EW GY++++GL+ VDFE P + R P SAK YA +I+N L
Sbjct: 413 VYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 147 bits (357), Expect = 3e-35
Identities = 77/233 (33%), Positives = 131/233 (56%)
Frame = -1
Query: 700 ADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEF 521
+D E A+ + FA PI+ +G +P +K+ + S +G+ ++R+ +FT EE +
Sbjct: 238 SDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKM 296
Query: 520 VKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPG 341
+KGT DF+A+ +YT+ ++K E + G+ +E + F P P+W+ + P G
Sbjct: 297 IKGTADFFAVQYYTTRLIKYQENKK--GELGILQDAE--IEFFPDPSWKNVDWIYVVPWG 352
Query: 340 LRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVT 161
+ + L ++K+ Y + ITE G+ L+D R + + E+ AI DK+N+
Sbjct: 353 VCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQ 412
Query: 160 GYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNRAL 2
Y WSL+D++EW GY++++GL+ VDFE P + R P SAK YA +I+N L
Sbjct: 413 VYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 147 bits (357), Expect = 3e-35
Identities = 77/233 (33%), Positives = 131/233 (56%)
Frame = -1
Query: 700 ADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEF 521
+D E A+ + FA PI+ +G +P +K+ + S +G+ ++R+ +FT EE +
Sbjct: 238 SDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKM 296
Query: 520 VKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPG 341
+KGT DF+A+ +YT+ ++K E + G+ +E + F P P+W+ + P G
Sbjct: 297 IKGTADFFAVQYYTTRLIKYQENKK--GELGILQDAE--IEFFPDPSWKNVDWIYVVPWG 352
Query: 340 LRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVT 161
+ + L ++K+ Y + ITE G+ L+D R + + E+ AI DK+N+
Sbjct: 353 VCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQ 412
Query: 160 GYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNRAL 2
Y WSL+D++EW GY++++GL+ VDFE P + R P SAK YA +I+N L
Sbjct: 413 VYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 147 bits (357), Expect = 3e-35
Identities = 77/233 (33%), Positives = 131/233 (56%)
Frame = -1
Query: 700 ADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEF 521
+D E A+ + FA PI+ +G +P +K+ + S +G+ ++R+ +FT EE +
Sbjct: 238 SDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKM 296
Query: 520 VKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPG 341
+KGT DF+A+ +YT+ ++K E + G+ +E + F P P+W+ + P G
Sbjct: 297 IKGTADFFAVQYYTTRLIKYQENKK--GELGILQDAE--IEFFPDPSWKNVDWIYVVPWG 352
Query: 340 LRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVT 161
+ + L ++K+ Y + ITE G+ L+D R + + E+ AI DK+N+
Sbjct: 353 VCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQ 412
Query: 160 GYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNRAL 2
Y WSL+D++EW GY++++GL+ VDFE P + R P SAK YA +I+N L
Sbjct: 413 VYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 146 bits (355), Expect = 5e-35
Identities = 77/233 (33%), Positives = 131/233 (56%)
Frame = -1
Query: 700 ADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEF 521
+D E A+ + FA PI+ +G +P +K+ + S +G+ ++R+ +FT EE +
Sbjct: 238 SDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKM 296
Query: 520 VKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPG 341
+KGT DF+A+ +YT+ ++K E + G+ +E + F P P+W+ + P G
Sbjct: 297 IKGTADFFAVQYYTTRLIKYQENKK--GELGTLQDAE--IEFFPDPSWKNVDWIYVVPWG 352
Query: 340 LRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVT 161
+ + L ++K+ Y + ITE G+ L+D R + + E+ AI DK+N+
Sbjct: 353 VCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQ 412
Query: 160 GYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNRAL 2
Y WSL+D++EW GY++++GL+ VDFE P + R P SAK YA +I+N L
Sbjct: 413 VYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 143 bits (347), Expect = 5e-34
Identities = 76/233 (32%), Positives = 129/233 (55%)
Frame = -1
Query: 700 ADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEF 521
+D E A+ + FA PI+ +G +P +K+ + S +G+ ++R+ +FT EE +
Sbjct: 238 SDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKM 296
Query: 520 VKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAGFGIYPPG 341
+KGT DF+A+ + T+ ++K E G+ +E + F P P+W+ + P G
Sbjct: 297 IKGTADFFAVQYCTTRLIKYQENKR--GELGILQDAE--IEFFPDPSWKNVDWIYVVPWG 352
Query: 340 LRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVT 161
+ + L ++K+ Y + ITE G+ L+D R + + E+ AI DK+N+
Sbjct: 353 VCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQ 412
Query: 160 GYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNRAL 2
Y WSL+D++EW GY++++GL+ VDFE P + R P SAK YA +I+N L
Sbjct: 413 VYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGL 465
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 99.5 bits (237), Expect = 1e-20
Identities = 46/109 (42%), Positives = 65/109 (59%)
Frame = -1
Query: 340 LRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVT 161
LR LNW+K Y + +I E G+ + D I +K++L++VL AI D+I V
Sbjct: 396 LREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVF 455
Query: 160 GYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
GYT WSL+D +EW+ YT + GL+ VDF S K R P+ SA YY +I+
Sbjct: 456 GYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 75.4 bits (177), Expect = 2e-13
Identities = 60/217 (27%), Positives = 104/217 (47%), Gaps = 2/217 (0%)
Frame = -1
Query: 652 FAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFVKGTYDFYALNHYTSF 473
FA P++ K G +P A++ + + + +G +++ + + T E +KGT DF ALNH+T+
Sbjct: 772 FAEPLF-KTGDYPAAMREYI-ASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTT- 828
Query: 472 VVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVS-AGFGIYPPGLRRQLNWLKNRYGDI 296
+ + + AG S+ + F T S + P G+R+ L W++ YGD+
Sbjct: 829 --RFVMHEQLAGS---RYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDM 883
Query: 295 PFMITETGYASYPFHGLNDDG-RINFIKDYLNEVLLAIYEDKINVTGYTVWSLMDSYEWE 119
IT +G L DD R ++ YL EVL A DK+ + GY + L E
Sbjct: 884 DIYITASGIDD---QALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLA-----E 935
Query: 118 SGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNR 8
++G + DF++ + S ++Y +I +R
Sbjct: 936 EKSKPRFGFFTSDFKA-------KSSIQFYNKVISSR 965
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 99.5 bits (237), Expect = 1e-20
Identities = 46/109 (42%), Positives = 65/109 (59%)
Frame = -1
Query: 340 LRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVT 161
LR LNW+K Y + +I E G+ + D I +K++L++VL AI D+I V
Sbjct: 396 LREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVF 455
Query: 160 GYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
GYT WSL+D +EW+ YT + GL+ VDF S K R P+ SA YY +I+
Sbjct: 456 GYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 75.4 bits (177), Expect = 2e-13
Identities = 60/217 (27%), Positives = 104/217 (47%), Gaps = 2/217 (0%)
Frame = -1
Query: 652 FAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFVKGTYDFYALNHYTSF 473
FA P++ K G +P A++ + + + +G +++ + + T E +KGT DF ALNH+T+
Sbjct: 772 FAEPLF-KTGDYPAAMREYI-ASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTT- 828
Query: 472 VVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVS-AGFGIYPPGLRRQLNWLKNRYGDI 296
+ + + AG S+ + F T S + P G+R+ L W++ YGD+
Sbjct: 829 --RFVMHEQLAGS---RYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDM 883
Query: 295 PFMITETGYASYPFHGLNDDG-RINFIKDYLNEVLLAIYEDKINVTGYTVWSLMDSYEWE 119
IT +G L DD R ++ YL EVL A DK+ + GY + L E
Sbjct: 884 DIYITASGIDD---QALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLA-----E 935
Query: 118 SGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNR 8
++G + DF++ + S ++Y +I +R
Sbjct: 936 EKSKPRFGFFTSDFKA-------KSSIQFYNKVISSR 965
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 99.5 bits (237), Expect = 1e-20
Identities = 46/109 (42%), Positives = 65/109 (59%)
Frame = -1
Query: 340 LRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKINVT 161
LR LNW+K Y + +I E G+ + D I +K++L++VL AI D+I V
Sbjct: 396 LREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVF 455
Query: 160 GYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
GYT WSL+D +EW+ YT + GL+ VDF S K R P+ SA YY +I+
Sbjct: 456 GYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 75.4 bits (177), Expect = 2e-13
Identities = 60/217 (27%), Positives = 104/217 (47%), Gaps = 2/217 (0%)
Frame = -1
Query: 652 FAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFVKGTYDFYALNHYTSF 473
FA P++ K G +P A++ + + + +G +++ + + T E +KGT DF ALNH+T+
Sbjct: 772 FAEPLF-KTGDYPAAMREYI-ASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTT- 828
Query: 472 VVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVS-AGFGIYPPGLRRQLNWLKNRYGDI 296
+ + + AG S+ + F T S + P G+R+ L W++ YGD+
Sbjct: 829 --RFVMHEQLAGS---RYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDM 883
Query: 295 PFMITETGYASYPFHGLNDDG-RINFIKDYLNEVLLAIYEDKINVTGYTVWSLMDSYEWE 119
IT +G L DD R ++ YL EVL A DK+ + GY + L E
Sbjct: 884 DIYITASGIDD---QALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLA-----E 935
Query: 118 SGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNR 8
++G + DF++ + S ++Y +I +R
Sbjct: 936 EKSKPRFGFFTSDFKA-------KSSIQFYNKVISSR 965
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 97.5 bits (232), Expect = 4e-20
Identities = 71/231 (30%), Positives = 115/231 (49%), Gaps = 1/231 (0%)
Frame = -1
Query: 706 TEADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEI 527
++ D E+AE E+ G A PI+ G +P +++ L++ NN + FT +E
Sbjct: 742 SQKDKEVAERVLEFDIGWLAEPIFGS-GDYPWVMRDWLNQR------NNFLLPYFTEDEK 794
Query: 526 EFVKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAG-FGIY 350
+ ++GT+DF AL+HYT+ +V + + + P + L V TW S +
Sbjct: 795 KLIQGTFDFLALSHYTTILVDSEKED------PIKYNDYLEVQEMTDITWLNSPSQVAVV 848
Query: 349 PPGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKI 170
P GLR+ LNWLK +YGD+P I G H +D R+ ++++Y+NE L A D I
Sbjct: 849 PWGLRKVLNWLKFKYGDLPMYIISNGIDD-GLHAEDDQLRVYYMQNYINEALKAHILDGI 907
Query: 169 NVTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLI 17
N+ GY +S D ++GLY+ + P+ S K+Y +I
Sbjct: 908 NLCGYFAYSFNDR------TAPRFGLYRYAADQ----FEPKASMKHYRKII 948
Score = 85.4 bits (202), Expect(2) = 4e-20
Identities = 41/111 (36%), Positives = 62/111 (55%)
Frame = -1
Query: 346 PGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKIN 167
P LR+ L+W+ + I E G+ +D + ++K ++ E L AI D ++
Sbjct: 392 PNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVD 451
Query: 166 VTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
V GYT WSLMD +EW GY+ + GL+ VDF S +K P+ SA +Y LI+
Sbjct: 452 VIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIE 502
Score = 32.7 bits (71), Expect(2) = 4e-20
Identities = 21/74 (28%), Positives = 40/74 (54%)
Frame = -1
Query: 670 EYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFVKGTYDFYAL 491
++ G FA P++ +G +P ++KN L ++ + FT E +F+KGT DF+AL
Sbjct: 321 DFVLGWFAKPVFI-DGDYPESMKNNL----------SSILPDFTESEKKFIKGTADFFAL 369
Query: 490 NHYTSFVVKAIEPN 449
+ + ++P+
Sbjct: 370 CFGPTLSFQLLDPH 383
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) protein.
Length = 1012
Score = 97.5 bits (232), Expect = 4e-20
Identities = 71/231 (30%), Positives = 115/231 (49%), Gaps = 1/231 (0%)
Frame = -1
Query: 706 TEADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEI 527
++ D E+AE E+ G A PI+ G +P +++ L++ NN + FT +E
Sbjct: 742 SQKDKEVAERVLEFDIGWLAEPIFGS-GDYPWVMRDWLNQR------NNFLLPYFTEDEK 794
Query: 526 EFVKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAG-FGIY 350
+ ++GT+DF AL+HYT+ +V + + + P + L V TW S +
Sbjct: 795 KLIQGTFDFLALSHYTTILVDSEKED------PIKYNDYLEVQEMTDITWLNSPSQVAVV 848
Query: 349 PPGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKI 170
P GLR+ LNWLK +YGD+P I G H +D R+ ++++Y+NE L A D I
Sbjct: 849 PWGLRKVLNWLKFKYGDLPMYIISNGIDD-GLHAEDDQLRVYYMQNYINEALKAHILDGI 907
Query: 169 NVTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLI 17
N+ GY +S D ++GLY+ + P+ S K+Y +I
Sbjct: 908 NLCGYFAYSFNDR------TAPRFGLYRYAADQ----FEPKASMKHYRKII 948
Score = 85.4 bits (202), Expect(2) = 4e-20
Identities = 41/111 (36%), Positives = 62/111 (55%)
Frame = -1
Query: 346 PGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKIN 167
P LR+ L+W+ + I E G+ +D + ++K ++ E L AI D ++
Sbjct: 392 PNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVD 451
Query: 166 VTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
V GYT WSLMD +EW GY+ + GL+ VDF S +K P+ SA +Y LI+
Sbjct: 452 VIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIE 502
Score = 32.7 bits (71), Expect(2) = 4e-20
Identities = 21/74 (28%), Positives = 40/74 (54%)
Frame = -1
Query: 670 EYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFVKGTYDFYAL 491
++ G FA P++ +G +P ++KN L ++ + FT E +F+KGT DF+AL
Sbjct: 321 DFVLGWFAKPVFI-DGDYPESMKNNL----------SSILPDFTESEKKFIKGTADFFAL 369
Query: 490 NHYTSFVVKAIEPN 449
+ + ++P+
Sbjct: 370 CFGPTLSFQLLDPH 383
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 97.5 bits (232), Expect = 4e-20
Identities = 71/231 (30%), Positives = 115/231 (49%), Gaps = 1/231 (0%)
Frame = -1
Query: 706 TEADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEI 527
++ D E+AE E+ G A PI+ G +P +++ L++ NN + FT +E
Sbjct: 742 SQKDKEVAERVLEFDIGWLAEPIFGS-GDYPWVMRDWLNQR------NNFLLPYFTEDEK 794
Query: 526 EFVKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAG-FGIY 350
+ ++GT+DF AL+HYT+ +V + + + P + L V TW S +
Sbjct: 795 KLIQGTFDFLALSHYTTILVDSEKED------PIKYNDYLEVQEMTDITWLNSPSQVAVV 848
Query: 349 PPGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKI 170
P GLR+ LNWLK +YGD+P I G H +D R+ ++++Y+NE L A D I
Sbjct: 849 PWGLRKVLNWLKFKYGDLPMYIISNGIDD-GLHAEDDQLRVYYMQNYINEALKAHILDGI 907
Query: 169 NVTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLI 17
N+ GY +S D ++GLY+ + P+ S K+Y +I
Sbjct: 908 NLCGYFAYSFNDR------TAPRFGLYRYAADQ----FEPKASMKHYRKII 948
Score = 85.4 bits (202), Expect(2) = 4e-20
Identities = 41/111 (36%), Positives = 62/111 (55%)
Frame = -1
Query: 346 PGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKIN 167
P LR+ L+W+ + I E G+ +D + ++K ++ E L AI D ++
Sbjct: 392 PNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVD 451
Query: 166 VTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
V GYT WSLMD +EW GY+ + GL+ VDF S +K P+ SA +Y LI+
Sbjct: 452 VIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIE 502
Score = 32.7 bits (71), Expect(2) = 4e-20
Identities = 21/74 (28%), Positives = 40/74 (54%)
Frame = -1
Query: 670 EYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFVKGTYDFYAL 491
++ G FA P++ +G +P ++KN L ++ + FT E +F+KGT DF+AL
Sbjct: 321 DFVLGWFAKPVFI-DGDYPESMKNNL----------SSILPDFTESEKKFIKGTADFFAL 369
Query: 490 NHYTSFVVKAIEPN 449
+ + ++P+
Sbjct: 370 CFGPTLSFQLLDPH 383
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 97.5 bits (232), Expect = 4e-20
Identities = 71/231 (30%), Positives = 115/231 (49%), Gaps = 1/231 (0%)
Frame = -1
Query: 706 TEADSELAELTNEYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEI 527
++ D E+AE E+ G A PI+ G +P +++ L++ NN + FT +E
Sbjct: 469 SQKDKEVAERVLEFDIGWLAEPIFGS-GDYPWVMRDWLNQR------NNFLLPYFTEDEK 521
Query: 526 EFVKGTYDFYALNHYTSFVVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVSAG-FGIY 350
+ ++GT+DF AL+HYT+ +V + + + P + L V TW S +
Sbjct: 522 KLIQGTFDFLALSHYTTILVDSEKED------PIKYNDYLEVQEMTDITWLNSPSQVAVV 575
Query: 349 PPGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKI 170
P GLR+ LNWLK +YGD+P I G H +D R+ ++++Y+NE L A D I
Sbjct: 576 PWGLRKVLNWLKFKYGDLPMYIISNGIDD-GLHAEDDQLRVYYMQNYINEALKAHILDGI 634
Query: 169 NVTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLI 17
N+ GY +S D ++GLY+ + P+ S K+Y +I
Sbjct: 635 NLCGYFAYSFNDR------TAPRFGLYRYAADQ----FEPKASMKHYRKII 675
Score = 85.4 bits (202), Expect(2) = 4e-20
Identities = 41/111 (36%), Positives = 62/111 (55%)
Frame = -1
Query: 346 PGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKIN 167
P LR+ L+W+ + I E G+ +D + ++K ++ E L AI D ++
Sbjct: 119 PNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVD 178
Query: 166 VTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
V GYT WSLMD +EW GY+ + GL+ VDF S +K P+ SA +Y LI+
Sbjct: 179 VIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIE 229
Score = 32.7 bits (71), Expect(2) = 4e-20
Identities = 21/74 (28%), Positives = 40/74 (54%)
Frame = -1
Query: 670 EYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFVKGTYDFYAL 491
++ G FA P++ +G +P ++KN L ++ + FT E +F+KGT DF+AL
Sbjct: 48 DFVLGWFAKPVFI-DGDYPESMKNNL----------SSILPDFTESEKKFIKGTADFFAL 96
Query: 490 NHYTSFVVKAIEPN 449
+ + ++P+
Sbjct: 97 CFGPTLSFQLLDPH 110
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 85.4 bits (202), Expect(2) = 4e-20
Identities = 41/111 (36%), Positives = 62/111 (55%)
Frame = -1
Query: 346 PGLRRQLNWLKNRYGDIPFMITETGYASYPFHGLNDDGRINFIKDYLNEVLLAIYEDKIN 167
P LR+ L+W+ + I E G+ +D + ++K ++ E L AI D ++
Sbjct: 392 PNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVD 451
Query: 166 VTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIK 14
V GYT WSLMD +EW GY+ + GL+ VDF S +K P+ SA +Y LI+
Sbjct: 452 VIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIE 502
Score = 32.7 bits (71), Expect(2) = 4e-20
Identities = 21/74 (28%), Positives = 40/74 (54%)
Frame = -1
Query: 670 EYCEGRFAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFVKGTYDFYAL 491
++ G FA P++ +G +P ++KN L ++ + FT E +F+KGT DF+AL
Sbjct: 321 DFVLGWFAKPVFI-DGDYPESMKNNL----------SSILPDFTESEKKFIKGTADFFAL 369
Query: 490 NHYTSFVVKAIEPN 449
+ + ++P+
Sbjct: 370 CFGPTLSFQLLDPH 383
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 77.4 bits (182), Expect = 5e-14
Identities = 31/63 (49%), Positives = 44/63 (69%)
Frame = -1
Query: 190 AIYEDKINVTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKN 11
AI DK+N+ Y WSL+D++EW GY++++GL+ VDFE P + R P SAK YA +I+N
Sbjct: 96 AIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 155
Query: 10 RAL 2
L
Sbjct: 156 NGL 158
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 77.4 bits (182), Expect = 5e-14
Identities = 31/63 (49%), Positives = 44/63 (69%)
Frame = -1
Query: 190 AIYEDKINVTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKN 11
AI DK+N+ Y WSL+D++EW GY++++GL+ VDFE P + R P SAK YA +I+N
Sbjct: 96 AIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 155
Query: 10 RAL 2
L
Sbjct: 156 NGL 158
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 77.4 bits (182), Expect = 5e-14
Identities = 31/63 (49%), Positives = 44/63 (69%)
Frame = -1
Query: 190 AIYEDKINVTGYTVWSLMDSYEWESGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKN 11
AI DK+N+ Y WSL+D++EW GY++++GL+ VDFE P + R P SAK YA +I+N
Sbjct: 96 AIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRN 155
Query: 10 RAL 2
L
Sbjct: 156 NGL 158
>BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein.
Length = 305
Score = 75.4 bits (177), Expect = 2e-13
Identities = 60/217 (27%), Positives = 104/217 (47%), Gaps = 2/217 (0%)
Frame = -1
Query: 652 FAYPIYSKEGGWPPALKNILDENSYNKGFNNTRVLQFTPEEIEFVKGTYDFYALNHYTSF 473
FA P++ K G +P A++ + + + +G +++ + + T E +KGT DF ALNH+T+
Sbjct: 33 FAEPLF-KTGDYPAAMREYI-ASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTT- 89
Query: 472 VVKAIEPNEAAGDWPFSGSSELGVNFGPHPTWEVS-AGFGIYPPGLRRQLNWLKNRYGDI 296
+ + + AG S+ + F T S + P G+R+ L W++ YGD+
Sbjct: 90 --RFVMHEQLAGS---RYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDM 144
Query: 295 PFMITETGYASYPFHGLNDDG-RINFIKDYLNEVLLAIYEDKINVTGYTVWSLMDSYEWE 119
IT +G L DD R ++ YL EVL A DK+ + GY + L E
Sbjct: 145 DIYITASGIDD---QALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLA-----E 196
Query: 118 SGYTAKYGLYQVDFESPNKTRTPRKSAKYYADLIKNR 8
++G + DF++ + S ++Y +I +R
Sbjct: 197 EKSKPRFGFFTSDFKA-------KSSIQFYNKVISSR 226
>BC028696-1|AAH28696.1| 281|Homo sapiens RAB40C, member RAS
oncogene family protein.
Length = 281
Score = 29.9 bits (64), Expect = 9.3
Identities = 11/20 (55%), Positives = 14/20 (70%)
Frame = -3
Query: 416 KRVRCELWTTSNMGGFCWVW 357
+RVR ELW TS G FC ++
Sbjct: 61 RRVRLELWDTSGQGRFCTIF 80
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 108,760,745
Number of Sequences: 237096
Number of extensions: 2540609
Number of successful extensions: 5367
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 5122
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5329
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8175213644
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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