Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= psV30308.Seq
(812 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000E49DF3 Cluster: PREDICTED: similar to serine hyd... 151 2e-35
UniRef50_P34896 Cluster: Serine hydroxymethyltransferase, cytoso... 150 5e-35
UniRef50_Q5BJF5 Cluster: Serine hydroxymethyltransferase; n=3; E... 137 4e-31
UniRef50_P34897 Cluster: Serine hydroxymethyltransferase, mitoch... 135 1e-30
UniRef50_Q5IWY0 Cluster: Plastid glycine hydroxymethyltransferas... 133 4e-30
UniRef50_O62585 Cluster: Serine hydroxymethyltransferase, cytoso... 131 2e-29
UniRef50_A4SBB9 Cluster: Serine hydroxymethyltransferase; n=11; ... 121 2e-26
UniRef50_Q9LM59 Cluster: Serine hydroxymethyltransferase; n=21; ... 114 2e-24
UniRef50_Q9U638 Cluster: SHMT; n=5; Aconoidasida|Rep: SHMT - Pla... 111 2e-23
UniRef50_Q7RQX7 Cluster: Serine hydroxymethyltransferase; n=4; P... 104 2e-21
UniRef50_A2EAE3 Cluster: Serine hydroxymethyltransferase; n=1; T... 103 4e-21
UniRef50_Q23KJ4 Cluster: Serine hydroxymethyltransferase family ... 102 9e-21
UniRef50_Q5CM80 Cluster: Serine hydroxymethyltransferase; n=2; C... 88 3e-16
UniRef50_Q98A81 Cluster: Serine hydroxymethyltransferase 2; n=4;... 85 2e-15
UniRef50_A0CF19 Cluster: Chromosome undetermined scaffold_174, w... 84 4e-15
UniRef50_Q89HS7 Cluster: Serine hydroxymethyltransferase; n=2; R... 82 1e-14
UniRef50_Q9RYB2 Cluster: Serine hydroxymethyltransferase; n=43; ... 77 5e-13
UniRef50_Q72IH2 Cluster: Serine hydroxymethyltransferase; n=6; B... 76 9e-13
UniRef50_Q8KC36 Cluster: Serine hydroxymethyltransferase; n=103;... 75 2e-12
UniRef50_A7D249 Cluster: Glycine hydroxymethyltransferase; n=1; ... 74 5e-12
UniRef50_Q8EWD1 Cluster: Serine hydroxymethyltransferase; n=14; ... 73 7e-12
UniRef50_Q9A8J6 Cluster: Serine hydroxymethyltransferase; n=42; ... 72 2e-11
UniRef50_Q9HPY5 Cluster: Serine hydroxymethyltransferase; n=79; ... 71 3e-11
UniRef50_Q6LHN7 Cluster: Serine hydroxymethyltransferase 2; n=27... 71 3e-11
UniRef50_A7R0L6 Cluster: Chromosome undetermined scaffold_311, w... 69 1e-10
UniRef50_Q8FQR1 Cluster: Serine hydroxymethyltransferase; n=37; ... 69 1e-10
UniRef50_Q183S3 Cluster: Serine hydroxymethyltransferase; n=1; C... 69 2e-10
UniRef50_Q057P9 Cluster: Serine hydroxymethyltransferase; n=3; G... 68 2e-10
UniRef50_A6PKY7 Cluster: Serine hydroxymethyltransferase; n=2; B... 67 6e-10
UniRef50_Q62I16 Cluster: Serine hydroxymethyltransferase 1; n=45... 66 8e-10
UniRef50_Q11NZ7 Cluster: Serine hydroxymethyltransferase; n=6; B... 66 1e-09
UniRef50_Q6G3L3 Cluster: Serine hydroxymethyltransferase; n=163;... 64 5e-09
UniRef50_Q05FV9 Cluster: Serine hydroxymethyltransferase; n=1; C... 60 7e-08
UniRef50_Q9UMD0 Cluster: 14 kDa protein; n=2; Homo sapiens|Rep: ... 55 2e-06
UniRef50_Q12RK5 Cluster: Glycine hydroxymethyltransferase; n=2; ... 54 3e-06
UniRef50_Q8TZ19 Cluster: Serine hydroxymethyltransferase; n=8; E... 54 4e-06
UniRef50_Q883D8 Cluster: Serine hydroxymethyltransferase, putati... 52 1e-05
UniRef50_O29406 Cluster: Serine hydroxymethyltransferase; n=6; E... 52 2e-05
UniRef50_Q5CM83 Cluster: Serine hydroxymethyltransferase 2; n=2;... 51 4e-05
UniRef50_Q1W396 Cluster: Glycine hydroxymethyltransferase; n=1; ... 48 2e-04
UniRef50_O83349 Cluster: Serine hydroxymethyltransferase; n=18; ... 45 3e-04
UniRef50_A0RYP2 Cluster: Glycine/serine hydroxymethyltransferase... 46 0.001
UniRef50_Q8ZYF9 Cluster: Serine hydroxymethyltransferase; n=5; T... 46 0.001
UniRef50_Q9PJW0 Cluster: Serine hydroxymethyltransferase; n=8; C... 45 0.003
UniRef50_Q9TSA5 Cluster: Serine hydroxymethyltransferase; n=1; O... 43 0.008
UniRef50_Q9YAH7 Cluster: Serine hydroxymethyltransferase; n=9; A... 41 0.043
UniRef50_A6TST7 Cluster: Glycine hydroxymethyltransferase; n=1; ... 40 0.075
UniRef50_Q9HI38 Cluster: Serine hydroxymethyltransferase; n=5; T... 38 0.23
UniRef50_Q6L0Q9 Cluster: Serine hydroxymethyltransferase; n=1; P... 38 0.30
UniRef50_Q5DH62 Cluster: SJCHGC03592 protein; n=1; Schistosoma j... 37 0.70
UniRef50_Q28QL6 Cluster: Glycine hydroxymethyltransferase; n=7; ... 36 1.6
>UniRef50_UPI0000E49DF3 Cluster: PREDICTED: similar to serine
hydroxymethyltransferase isoform 1; n=4; Coelomata|Rep:
PREDICTED: similar to serine hydroxymethyltransferase
isoform 1 - Strongylocentrotus purpuratus
Length = 496
Score = 151 bits (366), Expect = 2e-35
Identities = 65/83 (78%), Positives = 73/83 (87%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
RYYGG ++ DE+E+L Q R+L A+ LK EEWGVNVQPYSGSPANFAVYTG++ PHGRIMG
Sbjct: 133 RYYGGTQFFDEMELLTQKRALAAFGLKEEEWGVNVQPYSGSPANFAVYTGVIGPHGRIMG 192
Query: 439 LDLPDGGHLTHGFFTATKKISAT 507
LDLPDGGHLTHGF TA KKISAT
Sbjct: 193 LDLPDGGHLTHGFMTAKKKISAT 215
Score = 80.6 bits (190), Expect = 4e-14
Identities = 39/63 (61%), Positives = 46/63 (73%)
Frame = +2
Query: 86 NSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGT 265
+ +L E DPE++ II+KEKDRQR GLE+IASENF S VL+ L SCL NKY EG P N
Sbjct: 75 HQSLEENDPEMYAIILKEKDRQRKGLELIASENFPSRAVLEALGSCLQNKYCEGYPGNRY 134
Query: 266 MGG 274
GG
Sbjct: 135 YGG 137
Score = 68.9 bits (161), Expect = 1e-10
Identities = 37/79 (46%), Positives = 55/79 (69%)
Frame = +3
Query: 510 IFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXE 689
+FFESMPY+V+PK+GLIDY+ LA A+LF+P++IIAG + +++ YK +EI + +
Sbjct: 217 LFFESMPYRVNPKTGLIDYEALAVNARLFRPQMIIAGMSCYPRNLD-YKRFKEI-AVEND 274
Query: 690 LNLMADXGSRYLGLVAGQV 746
L+AD + GLVA V
Sbjct: 275 AYLLADM-AHVSGLVAAGV 292
>UniRef50_P34896 Cluster: Serine hydroxymethyltransferase,
cytosolic; n=86; root|Rep: Serine
hydroxymethyltransferase, cytosolic - Homo sapiens
(Human)
Length = 483
Score = 150 bits (363), Expect = 5e-35
Identities = 66/84 (78%), Positives = 73/84 (86%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 436 GLDLPDGGHLTHGFFTATKKISAT 507
GLDLPDGGHLTHGF T KKISAT
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISAT 163
Score = 75.8 bits (178), Expect = 1e-12
Identities = 37/70 (52%), Positives = 48/70 (68%)
Frame = +2
Query: 77 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPI 256
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 257 NGTMGGMNIL 286
GG +
Sbjct: 80 QRYYGGTEFI 89
Score = 66.1 bits (154), Expect = 1e-09
Identities = 38/79 (48%), Positives = 51/79 (64%)
Frame = +3
Query: 510 IFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXE 689
IFFESMPYKV+P +G I+YD+L E A+LF P+LIIAG +++++ Y R+I
Sbjct: 165 IFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLE-YARLRKIADENGA 223
Query: 690 LNLMADXGSRYLGLVAGQV 746
LMAD + GLVA V
Sbjct: 224 Y-LMADM-AHISGLVAAGV 240
>UniRef50_Q5BJF5 Cluster: Serine hydroxymethyltransferase; n=3;
Euarchontoglires|Rep: Serine hydroxymethyltransferase -
Homo sapiens (Human)
Length = 480
Score = 137 bits (331), Expect = 4e-31
Identities = 59/84 (70%), Positives = 70/84 (83%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
QRYYGG E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIM
Sbjct: 79 QRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIM 138
Query: 436 GLDLPDGGHLTHGFFTATKKISAT 507
GLDLPDGGHLTHG+ + K+ISAT
Sbjct: 139 GLDLPDGGHLTHGYMSDVKRISAT 162
Score = 73.3 bits (172), Expect = 7e-12
Identities = 40/79 (50%), Positives = 57/79 (72%)
Frame = +3
Query: 510 IFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXE 689
IFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG + + + Y RE+ + +
Sbjct: 164 IFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLID-YARMREV-CDEVK 221
Query: 690 LNLMADXGSRYLGLVAGQV 746
+L+AD + GLVA +V
Sbjct: 222 AHLLADM-AHISGLVAAKV 239
>UniRef50_P34897 Cluster: Serine hydroxymethyltransferase,
mitochondrial precursor; n=160; Eukaryota|Rep: Serine
hydroxymethyltransferase, mitochondrial precursor - Homo
sapiens (Human)
Length = 504
Score = 135 bits (327), Expect = 1e-30
Identities = 58/84 (69%), Positives = 70/84 (83%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYYGG E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIM
Sbjct: 103 KRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIM 162
Query: 436 GLDLPDGGHLTHGFFTATKKISAT 507
GLDLPDGGHLTHG+ + K+ISAT
Sbjct: 163 GLDLPDGGHLTHGYMSDVKRISAT 186
Score = 73.3 bits (172), Expect = 7e-12
Identities = 33/65 (50%), Positives = 47/65 (72%)
Frame = +2
Query: 92 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGTMG 271
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P G
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 272 GMNIL 286
G ++
Sbjct: 108 GAEVV 112
Score = 73.3 bits (172), Expect = 7e-12
Identities = 40/79 (50%), Positives = 57/79 (72%)
Frame = +3
Query: 510 IFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXE 689
IFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG + + + Y RE+ + +
Sbjct: 188 IFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLID-YARMREV-CDEVK 245
Query: 690 LNLMADXGSRYLGLVAGQV 746
+L+AD + GLVA +V
Sbjct: 246 AHLLADM-AHISGLVAAKV 263
>UniRef50_Q5IWY0 Cluster: Plastid glycine hydroxymethyltransferase;
n=1; Prototheca wickerhamii|Rep: Plastid glycine
hydroxymethyltransferase - Prototheca wickerhamii
Length = 218
Score = 133 bits (322), Expect = 4e-30
Identities = 58/83 (69%), Positives = 68/83 (81%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
RYYGGNE+ID+ E L Q R+LEA+ L EWGVNVQP+SGSPANFAVYT ++ PH RIMG
Sbjct: 128 RYYGGNEFIDQAESLCQRRALEAFGLDPAEWGVNVQPHSGSPANFAVYTALLSPHDRIMG 187
Query: 439 LDLPDGGHLTHGFFTATKKISAT 507
LDLP GGHLTHGF T +++SAT
Sbjct: 188 LDLPHGGHLTHGFQTPKRRVSAT 210
Score = 69.3 bits (162), Expect = 1e-10
Identities = 35/63 (55%), Positives = 43/63 (68%)
Frame = +2
Query: 86 NSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGT 265
+ +L E DPE+ II KEK RQ GLE+IASENFTS V+ + SC+ NKYSEG+P
Sbjct: 70 DGSLDEVDPEIASIIRKEKVRQVTGLELIASENFTSRAVMTAVGSCMTNKYSEGLPGARY 129
Query: 266 MGG 274
GG
Sbjct: 130 YGG 132
>UniRef50_O62585 Cluster: Serine hydroxymethyltransferase,
cytosolic; n=1; Encephalitozoon cuniculi|Rep: Serine
hydroxymethyltransferase, cytosolic - Encephalitozoon
cuniculi
Length = 460
Score = 131 bits (317), Expect = 2e-29
Identities = 56/84 (66%), Positives = 68/84 (80%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYYGG ++D IE+L Q R+LE + L + WGVNVQPYSGSPANFA+YT +V P GRIM
Sbjct: 68 ERYYGGTHWVDRIELLCQKRALELFGLDPDVWGVNVQPYSGSPANFAIYTAVVPPGGRIM 127
Query: 436 GLDLPDGGHLTHGFFTATKKISAT 507
GLDLP GGHLTHG+ T T+KISA+
Sbjct: 128 GLDLPSGGHLTHGYKTKTRKISAS 151
Score = 47.2 bits (107), Expect = 5e-04
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +2
Query: 104 ADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEG 247
ADPEL +I E +RQ+ + +IASEN+ ++ S L NKYSEG
Sbjct: 17 ADPELHALICGEVERQKKTINLIASENYAHQSAMEACGSVLTNKYSEG 64
Score = 44.0 bits (99), Expect = 0.005
Identities = 24/66 (36%), Positives = 38/66 (57%)
Frame = +3
Query: 510 IFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXE 689
++F+S PY V +GLIDY+ L +T F P ++I G+ +++D+ YK + I R
Sbjct: 153 VYFDSRPYTVG-SNGLIDYEGLEKTFTDFLPHILICGYSAYSRDID-YKRLQSIAGRNGA 210
Query: 690 LNLMAD 707
L AD
Sbjct: 211 F-LFAD 215
>UniRef50_A4SBB9 Cluster: Serine hydroxymethyltransferase; n=11;
Viridiplantae|Rep: Serine hydroxymethyltransferase -
Ostreococcus lucimarinus CCE9901
Length = 525
Score = 121 bits (292), Expect = 2e-26
Identities = 53/83 (63%), Positives = 65/83 (78%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
RYYGGNE+ID E + Q R+L+A+ L +WGVNVQ SGSPANF VYT +++PH +IM
Sbjct: 118 RYYGGNEFIDMAESMCQERALKAFNLDPAKWGVNVQSLSGSPANFQVYTALLQPHDKIMA 177
Query: 439 LDLPDGGHLTHGFFTATKKISAT 507
LDLP GGHL+HG+ T TKKISAT
Sbjct: 178 LDLPHGGHLSHGYQTDTKKISAT 200
Score = 63.3 bits (147), Expect = 7e-09
Identities = 31/66 (46%), Positives = 42/66 (63%)
Frame = +2
Query: 77 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPI 256
+++N + E DPE+ +II +EK RQ GLE+I SENF S V+ + S + NKYSEG P
Sbjct: 57 EIINKPIEEVDPEMSEIIEREKARQWKGLELIPSENFVSKSVMDAVGSIMTNKYSEGYPG 116
Query: 257 NGTMGG 274
GG
Sbjct: 117 ARYYGG 122
Score = 54.0 bits (124), Expect = 4e-06
Identities = 33/80 (41%), Positives = 49/80 (61%), Gaps = 1/80 (1%)
Frame = +3
Query: 510 IFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXE 689
IFF S+PY++D +GLIDYD +TA L +P+LI+AG + + + Y R+I
Sbjct: 202 IFFTSVPYRLDESTGLIDYDACEKTAALVRPKLIVAGASAYAR-LYDYPRMRKIADNSNA 260
Query: 690 LNLMADXGSRYLGLV-AGQV 746
+ L+AD + GLV AG+V
Sbjct: 261 I-LLADM-AHISGLVAAGEV 278
>UniRef50_Q9LM59 Cluster: Serine hydroxymethyltransferase; n=21;
Eukaryota|Rep: Serine hydroxymethyltransferase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 599
Score = 114 bits (275), Expect = 2e-24
Identities = 51/82 (62%), Positives = 65/82 (79%), Gaps = 1/82 (1%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
RYY GN+YID+IEIL Q R+L A+ L E+WGVNVQPYS + ANFAV+TG++ P RIMG
Sbjct: 197 RYYTGNQYIDQIEILCQERALAAFGLNHEKWGVNVQPYSCTSANFAVFTGLLMPGERIMG 256
Query: 439 LDLPDGGHLTHGFFT-ATKKIS 501
LD P GGH++HG++T KK+S
Sbjct: 257 LDSPSGGHMSHGYYTPGGKKVS 278
Score = 66.5 bits (155), Expect = 8e-10
Identities = 31/56 (55%), Positives = 40/56 (71%)
Frame = +2
Query: 86 NSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMP 253
N ++ EADPE+ + + KEK RQ G+E+IASENF V++ L S L NKYSEGMP
Sbjct: 139 NQSIEEADPEIHEFMEKEKQRQFRGIELIASENFVCRAVMEALGSHLTNKYSEGMP 194
Score = 58.4 bits (135), Expect = 2e-07
Identities = 24/44 (54%), Positives = 33/44 (75%)
Frame = +3
Query: 510 IFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQD 641
IFFES PYKVDP++G IDYDKL E A ++P+++I G + +D
Sbjct: 282 IFFESFPYKVDPRTGYIDYDKLEEKALDYRPKILICGGSSYPRD 325
>UniRef50_Q9U638 Cluster: SHMT; n=5; Aconoidasida|Rep: SHMT -
Plasmodium falciparum
Length = 442
Score = 111 bits (267), Expect = 2e-23
Identities = 49/87 (56%), Positives = 61/87 (70%)
Frame = +1
Query: 247 HAHQRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHG 426
+ H+RYYGGN+Y+D+IE L R+LEA+ + EEWGVNVQP SGS AN +V G
Sbjct: 58 YPHKRYYGGNDYVDKIEELCYKRALEAFNVSEEEWGVNVQPLSGSAANVQALYALVGVKG 117
Query: 427 RIMGLDLPDGGHLTHGFFTATKKISAT 507
+IMG+ L GGHLTHGFF KK+S T
Sbjct: 118 KIMGMHLCSGGHLTHGFFDEKKKVSIT 144
Score = 62.1 bits (144), Expect = 2e-08
Identities = 31/69 (44%), Positives = 42/69 (60%)
Frame = +2
Query: 86 NSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGT 265
N L + D ELFD++ KEK+RQ + +IASEN T+ V +CL + NKYSEG P
Sbjct: 4 NDPLQKYDKELFDLLEKEKNRQIETINLIASENLTNTAVRECLGDRISNKYSEGYPHKRY 63
Query: 266 MGGMNILMK 292
GG + + K
Sbjct: 64 YGGNDYVDK 72
>UniRef50_Q7RQX7 Cluster: Serine hydroxymethyltransferase; n=4;
Plasmodium|Rep: Serine hydroxymethyltransferase -
Plasmodium yoelii yoelii
Length = 446
Score = 104 bits (250), Expect = 2e-21
Identities = 48/87 (55%), Positives = 59/87 (67%)
Frame = +1
Query: 247 HAHQRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHG 426
+ +RYYGGN+YID+IE L R+LE + L SEEWGVNVQ SGS AN +V G
Sbjct: 62 YPRKRYYGGNDYIDKIEELCCKRALETFNLNSEEWGVNVQSLSGSAANVQALYALVGIKG 121
Query: 427 RIMGLDLPDGGHLTHGFFTATKKISAT 507
+I+G+ L GGHLTHGFF KK+S T
Sbjct: 122 KILGMHLCSGGHLTHGFFDEKKKVSVT 148
Score = 56.4 bits (130), Expect = 8e-07
Identities = 27/69 (39%), Positives = 41/69 (59%)
Frame = +2
Query: 86 NSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGT 265
N L ++D EL+ I++ E+ RQ+ + +IASEN + V +CL + NKYSEG P
Sbjct: 8 NEPLEKSDKELYSILLDEEKRQKETINLIASENLINASVKECLGHVVSNKYSEGYPRKRY 67
Query: 266 MGGMNILMK 292
GG + + K
Sbjct: 68 YGGNDYIDK 76
>UniRef50_A2EAE3 Cluster: Serine hydroxymethyltransferase; n=1;
Trichomonas vaginalis G3|Rep: Serine
hydroxymethyltransferase - Trichomonas vaginalis G3
Length = 451
Score = 103 bits (248), Expect = 4e-21
Identities = 45/83 (54%), Positives = 58/83 (69%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
RYYGG +Y+DE+E + R+L+ + L +EWGVNVQ SGSPAN AVYT ++ P MG
Sbjct: 75 RYYGGTKYVDELENETKRRALDLFNLNPKEWGVNVQALSGSPANLAVYTALLNPGDTFMG 134
Query: 439 LDLPDGGHLTHGFFTATKKISAT 507
L L DGGHLTHG KK+S++
Sbjct: 135 LKLSDGGHLTHGHKLKAKKVSSS 157
Score = 50.4 bits (115), Expect = 5e-05
Identities = 28/76 (36%), Positives = 47/76 (61%)
Frame = +3
Query: 510 IFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXE 689
IF+ S Y ++PK+ LID++KL + AK P+LI+AG + + + +K R+I +
Sbjct: 159 IFWNSEQYTLNPKTSLIDFEKLEQKAKELHPKLIVAGASAYPRFID-FKEFRKICNQTNS 217
Query: 690 LNLMADXGSRYLGLVA 737
+ LM+D + Y GL+A
Sbjct: 218 I-LMSDV-AHYSGLIA 231
Score = 49.6 bits (113), Expect = 9e-05
Identities = 31/76 (40%), Positives = 44/76 (57%)
Frame = +2
Query: 47 RYISSTKMSAKLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCL 226
R+ SS +S K+L E D + +I + E RQ+ G+E+IASEN+ S L LS+
Sbjct: 8 RFSSSWILSEKVLA----EKDRVINEIHLNEVKRQKEGIELIASENYPSRACLAALSTHF 63
Query: 227 HNKYSEGMPINGTMGG 274
+NKY+EG P GG
Sbjct: 64 NNKYAEGYPGARYYGG 79
>UniRef50_Q23KJ4 Cluster: Serine hydroxymethyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep: Serine
hydroxymethyltransferase family protein - Tetrahymena
thermophila SB210
Length = 515
Score = 102 bits (245), Expect = 9e-21
Identities = 44/82 (53%), Positives = 61/82 (74%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
RYYGGN++ID++EIL QNR+LE + L EWG+NVQ +S +PANF V TG+++ H R+M
Sbjct: 116 RYYGGNQFIDKMEILCQNRALELFGLNPSEWGINVQAHSLTPANFHVLTGLLQNHDRVMS 175
Query: 439 LDLPDGGHLTHGFFTATKKISA 504
L + GGHL+HG +K+SA
Sbjct: 176 LSIEHGGHLSHGQNFKREKLSA 197
Score = 67.7 bits (158), Expect = 3e-10
Identities = 31/70 (44%), Positives = 47/70 (67%)
Frame = +2
Query: 83 LNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPING 262
LN + EADP+L +II KE RQ++ + +I SEN+TS+ Q + S +++KYSEG+P+N
Sbjct: 57 LNQGIKEADPQLNEIIQKEIQRQKSTINLIPSENYTSLSAKQAVGSIMNSKYSEGLPLNR 116
Query: 263 TMGGMNILMK 292
GG + K
Sbjct: 117 YYGGNQFIDK 126
Score = 54.4 bits (125), Expect = 3e-06
Identities = 30/79 (37%), Positives = 49/79 (62%)
Frame = +3
Query: 510 IFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXE 689
++FE + Y ++ KSGLIDYDKL E +K F P++I G +L+++ + Y+ R+I
Sbjct: 200 VYFEILNYGINEKSGLIDYDKLEEQSKYFLPKVIFGGADLYSRKID-YERLRKI-CDSIG 257
Query: 690 LNLMADXGSRYLGLVAGQV 746
L+ D G + GLVA ++
Sbjct: 258 ATLVVDLG-QVSGLVATKI 275
>UniRef50_Q5CM80 Cluster: Serine hydroxymethyltransferase; n=2;
Cryptosporidium|Rep: Serine hydroxymethyltransferase -
Cryptosporidium hominis
Length = 445
Score = 87.8 bits (208), Expect = 3e-16
Identities = 38/73 (52%), Positives = 52/73 (71%)
Frame = +1
Query: 289 EIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLPDGGHLT 468
E+ L R+L+AY L E WG NV+P+SGSPANFAV +++P+ RIMGL L GGHLT
Sbjct: 70 ELLELTNERALKAYGLDPEVWGANVKPHSGSPANFAVLNAVLKPNDRIMGLSLQHGGHLT 129
Query: 469 HGFFTATKKISAT 507
HG +T K+++ +
Sbjct: 130 HGHYTNLKRVNCS 142
Score = 53.2 bits (122), Expect = 7e-06
Identities = 33/78 (42%), Positives = 49/78 (62%)
Frame = +3
Query: 501 CYVIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRR 680
C +FES+PY D + G+IDYDKL E A LF+P++IIAG + + ++ +K R+I +
Sbjct: 141 CSSHYFESLPYVTDLE-GVIDYDKLEENAILFRPKMIIAGASGYPRMIN-FKRFRDICDK 198
Query: 681 QXELNLMADXGSRYLGLV 734
+ LM D + Y GLV
Sbjct: 199 -VKAYLMVDI-AHYSGLV 214
Score = 48.8 bits (111), Expect = 2e-04
Identities = 29/63 (46%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
Frame = +2
Query: 80 LLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHN-KYSEGMPI 256
L +L E DP ++++I +E DRQ GLEMIASENF S VL LSS + M +
Sbjct: 4 LQEKSLKELDPIMYELINEEYDRQINGLEMIASENFVSRGVLDSLSSTFSMFNNDKNMEL 63
Query: 257 NGT 265
N T
Sbjct: 64 NST 66
>UniRef50_Q98A81 Cluster: Serine hydroxymethyltransferase 2; n=4;
Bacteria|Rep: Serine hydroxymethyltransferase 2 -
Rhizobium loti (Mesorhizobium loti)
Length = 437
Score = 85.0 bits (201), Expect = 2e-15
Identities = 43/73 (58%), Positives = 52/73 (71%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
RYY GNE +DE+E LA R L+A SE NVQPYSGSPAN AVY ++ P ++MG
Sbjct: 67 RYYAGNEIVDELETLAIER-LKAL-FGSEH--ANVQPYSGSPANQAVYRALLSPRDKVMG 122
Query: 439 LDLPDGGHLTHGF 477
L LP+GGHLTHG+
Sbjct: 123 LPLPEGGHLTHGW 135
Score = 48.4 bits (110), Expect = 2e-04
Identities = 21/55 (38%), Positives = 37/55 (67%)
Frame = +2
Query: 89 SNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMP 253
S+L + D + +++++++ ++R L++IASENF S VL+ S NKY+EG P
Sbjct: 10 SSLVQVDCRVHELLLRQRRQERTMLKLIASENFASSAVLEATGSIFANKYAEGYP 64
Score = 35.9 bits (79), Expect = 1.2
Identities = 15/35 (42%), Positives = 24/35 (68%)
Frame = +3
Query: 516 FESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAG 620
++ +PY + K+ IDYD+L ETA+ +P+LI G
Sbjct: 144 YQRVPYGLHDKTQQIDYDRLRETARRERPKLIWVG 178
>UniRef50_A0CF19 Cluster: Chromosome undetermined scaffold_174,
whole genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_174,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 439
Score = 84.2 bits (199), Expect = 4e-15
Identities = 37/76 (48%), Positives = 51/76 (67%)
Frame = +1
Query: 277 EYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLPDG 456
E DEIE L Q R+L A++L ++WGVN Q SGS AN A++ G++EP RIM ++ G
Sbjct: 73 ENYDEIEKLCQERALTAFQLDPQQWGVNAQMGSGSSANLAIFLGLLEPKDRIMSMEFQQG 132
Query: 457 GHLTHGFFTATKKISA 504
GH +HG+ KK+SA
Sbjct: 133 GHFSHGYQIGEKKLSA 148
Score = 41.9 bits (94), Expect = 0.018
Identities = 19/51 (37%), Positives = 32/51 (62%)
Frame = +2
Query: 95 LWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEG 247
L + D E++ +I KEK+ Q+ + +I SEN+TS V + LS ++Y+ G
Sbjct: 12 LQQQDIEIYQLIEKEKNLQQNSINLIPSENYTSRAVAEALSCVFSSRYAPG 62
Score = 39.5 bits (88), Expect = 0.099
Identities = 17/41 (41%), Positives = 29/41 (70%)
Frame = +3
Query: 516 FESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQ 638
FE + Y+++ K+ IDYDK+ AK +KP+LI+AG +++
Sbjct: 153 FEVLFYQLNEKTQEIDYDKVEILAKAYKPKLIVAGCSAYSK 193
>UniRef50_Q89HS7 Cluster: Serine hydroxymethyltransferase; n=2;
Rhizobiales|Rep: Serine hydroxymethyltransferase -
Bradyrhizobium japonicum
Length = 460
Score = 82.2 bits (194), Expect = 1e-14
Identities = 39/73 (53%), Positives = 49/73 (67%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYYGG +Y DEIE LA+ R+ +R + NVQP SGSP N AVY G++EP I+
Sbjct: 93 RRYYGGQQYTDEIERLARERACSLFRAEH----ANVQPLSGSPMNQAVYLGLLEPGDTIL 148
Query: 436 GLDLPDGGHLTHG 474
+DL GGHLTHG
Sbjct: 149 AMDLSHGGHLTHG 161
Score = 50.4 bits (115), Expect = 5e-05
Identities = 26/56 (46%), Positives = 34/56 (60%)
Frame = +2
Query: 107 DPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGTMGG 274
D E+ +V E+ RQ+ G+E+I SEN+T VL+ L S NKYSEG P GG
Sbjct: 43 DQEIAAALVGEERRQQDGVELIPSENYTYPEVLELLGSVFTNKYSEGYPGRRYYGG 98
>UniRef50_Q9RYB2 Cluster: Serine hydroxymethyltransferase; n=43;
Bacteria|Rep: Serine hydroxymethyltransferase -
Deinococcus radiodurans
Length = 408
Score = 77.0 bits (181), Expect = 5e-13
Identities = 35/73 (47%), Positives = 51/73 (69%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+R+YGG E +D++E LA +R + + + EW NVQP+SGS AN AVY +++P ++
Sbjct: 62 KRWYGGCEVVDQVEQLAIDRVKQLF---NAEWA-NVQPHSGSSANLAVYNALIQPGDTVL 117
Query: 436 GLDLPDGGHLTHG 474
G+DL GGHLTHG
Sbjct: 118 GMDLSHGGHLTHG 130
Score = 63.7 bits (148), Expect = 5e-09
Identities = 30/60 (50%), Positives = 39/60 (65%)
Frame = +2
Query: 107 DPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGTMGGMNIL 286
D +FD+I +E +RQR GLE+IASENFTS V + S L NKY+EG P GG ++
Sbjct: 12 DDAVFDLIAQEAERQRTGLELIASENFTSAAVREAQGSVLTNKYAEGYPGKRWYGGCEVV 71
>UniRef50_Q72IH2 Cluster: Serine hydroxymethyltransferase; n=6;
Bacteria|Rep: Serine hydroxymethyltransferase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 407
Score = 76.2 bits (179), Expect = 9e-13
Identities = 40/72 (55%), Positives = 46/72 (63%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
RYYGG E ID +E LA R A L W NVQP+SGS AN AVY ++EP +MG
Sbjct: 59 RYYGGCEAIDRVESLAIER---AKALFGAAWA-NVQPHSGSQANMAVYMALMEPGDTLMG 114
Query: 439 LDLPDGGHLTHG 474
+DL GGHLTHG
Sbjct: 115 MDLAAGGHLTHG 126
Score = 57.6 bits (133), Expect = 3e-07
Identities = 29/56 (51%), Positives = 36/56 (64%)
Frame = +2
Query: 107 DPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGTMGG 274
D LF++I E+ RQR GLE+IASENF S V + + S L NKY+EG P GG
Sbjct: 8 DEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGG 63
>UniRef50_Q8KC36 Cluster: Serine hydroxymethyltransferase; n=103;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Chlorobium tepidum
Length = 440
Score = 74.9 bits (176), Expect = 2e-12
Identities = 40/73 (54%), Positives = 51/73 (69%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYYGG E++D E LA++R A +L E+ VNVQP+SGS AN AV +++P IM
Sbjct: 60 KRYYGGCEFVDVAENLARDR---AKKLFGCEY-VNVQPHSGSSANMAVLFAVLKPGDAIM 115
Query: 436 GLDLPDGGHLTHG 474
GLDL GGHLTHG
Sbjct: 116 GLDLSHGGHLTHG 128
Score = 59.3 bits (137), Expect = 1e-07
Identities = 30/63 (47%), Positives = 37/63 (58%)
Frame = +2
Query: 86 NSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGT 265
N L DPE+F+ I E RQ LE+IASENFTS V++ S + NKY+EG P
Sbjct: 3 NDILKRLDPEVFEAIANETKRQTETLELIASENFTSKAVMEACGSVMTNKYAEGYPGKRY 62
Query: 266 MGG 274
GG
Sbjct: 63 YGG 65
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/75 (40%), Positives = 45/75 (60%)
Frame = +3
Query: 513 FFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXEL 692
FF++ Y VD ++G+ID +K+ E A+ KP+LII G ++Q +K RE+ + L
Sbjct: 137 FFDAHSYGVDKETGIIDMNKVEEMARRVKPKLIITGASAYSQGFD-FKAFREVADKVGAL 195
Query: 693 NLMADXGSRYLGLVA 737
LMAD + GLVA
Sbjct: 196 -LMADI-AHPAGLVA 208
>UniRef50_A7D249 Cluster: Glycine hydroxymethyltransferase; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: Glycine
hydroxymethyltransferase - Halorubrum lacusprofundi ATCC
49239
Length = 460
Score = 73.7 bits (173), Expect = 5e-12
Identities = 36/73 (49%), Positives = 49/73 (67%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYY G EY DE+E LA +R+ E + VNVQP+SG+ AN AVY +++P +I+
Sbjct: 105 ERYYAGCEYADEVETLAIDRAKELWGADH----VNVQPHSGTQANQAVYYAVLDPGDKIL 160
Query: 436 GLDLPDGGHLTHG 474
LDL GGHL+HG
Sbjct: 161 SLDLNHGGHLSHG 173
Score = 55.2 bits (127), Expect = 2e-06
Identities = 27/51 (52%), Positives = 32/51 (62%)
Frame = +2
Query: 101 EADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMP 253
E DPE+ D + E+DRQ L MIASEN S VL+ S L NKY+EG P
Sbjct: 53 EVDPEVADALAGERDRQEQTLAMIASENHVSEAVLEAQGSVLTNKYAEGYP 103
Score = 38.7 bits (86), Expect = 0.17
Identities = 15/43 (34%), Positives = 28/43 (65%)
Frame = +3
Query: 516 FESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDV 644
+E Y+VD +G IDY+ L E A+ F+P ++++G+ + + V
Sbjct: 183 YEVEQYEVDADTGYIDYEGLREAAEEFEPDIVVSGYSAYPRTV 225
>UniRef50_Q8EWD1 Cluster: Serine hydroxymethyltransferase; n=14;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Mycoplasma penetrans
Length = 412
Score = 73.3 bits (172), Expect = 7e-12
Identities = 33/76 (43%), Positives = 52/76 (68%)
Frame = +1
Query: 247 HAHQRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHG 426
+ ++RYYGG EY D+IE LA +++ E + K NVQP+SG+ AN A Y +++P+
Sbjct: 50 YPNRRYYGGCEYADQIEQLAIDKAKEIFNAKF----ANVQPHSGTQANVAAYLSVLKPND 105
Query: 427 RIMGLDLPDGGHLTHG 474
+I+ + L +GGHL+HG
Sbjct: 106 KILAMGLNEGGHLSHG 121
Score = 44.0 bits (99), Expect = 0.005
Identities = 22/53 (41%), Positives = 30/53 (56%)
Frame = +2
Query: 116 LFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGTMGG 274
L +I+ E RQ+ +E+IASEN+ S +L+ S NKY EG P GG
Sbjct: 6 LKEILNNELKRQQGYIELIASENYVSEQILEATGSVFTNKYCEGYPNRRYYGG 58
Score = 33.9 bits (74), Expect = 4.9
Identities = 15/47 (31%), Positives = 28/47 (59%)
Frame = +3
Query: 516 FESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYK 656
+E+ Y VD ++ +DYD + + A+ KP+LI+ G +++ V K
Sbjct: 131 YEADHYGVDKETQCLDYDAILKQAQEVKPKLIVCGASNYSRVVDFKK 177
>UniRef50_Q9A8J6 Cluster: Serine hydroxymethyltransferase; n=42;
Bacteria|Rep: Serine hydroxymethyltransferase -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 429
Score = 72.1 bits (169), Expect = 2e-11
Identities = 35/73 (47%), Positives = 47/73 (64%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYYGG EY+DEIE +A R+ + NVQP+SGS AN AV+ +++P +
Sbjct: 69 KRYYGGCEYVDEIETIAIERAKALFGAGF----ANVQPHSGSQANQAVFMALLQPGDTFL 124
Query: 436 GLDLPDGGHLTHG 474
G+DL GGHLTHG
Sbjct: 125 GMDLAAGGHLTHG 137
Score = 54.4 bits (125), Expect = 3e-06
Identities = 31/74 (41%), Positives = 44/74 (59%)
Frame = +2
Query: 53 ISSTKMSAKLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHN 232
++ T +SA ++L AD ++FD I +E RQ+ +E+IASEN S VL+ S L N
Sbjct: 2 MTQTDLSA-FFGADLATADRDIFDRIGRELGRQQNQIELIASENIVSKAVLEAQGSILTN 60
Query: 233 KYSEGMPINGTMGG 274
KY+EG P GG
Sbjct: 61 KYAEGYPGKRYYGG 74
Score = 48.4 bits (110), Expect = 2e-04
Identities = 30/76 (39%), Positives = 44/76 (57%)
Frame = +3
Query: 513 FFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXEL 692
+F+ + Y V + LIDYD +AE A+ KP+LIIAG +++++ K REI
Sbjct: 146 WFKPISYSVRQQDQLIDYDGVAEVAQREKPKLIIAGGSAYSREIDFAK-FREI-ADSIGA 203
Query: 693 NLMADXGSRYLGLVAG 740
LM D + Y GL+AG
Sbjct: 204 YLMVDM-AHYAGLIAG 218
>UniRef50_Q9HPY5 Cluster: Serine hydroxymethyltransferase; n=79;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Halobacterium salinarium (Halobacterium halobium)
Length = 415
Score = 71.3 bits (167), Expect = 3e-11
Identities = 36/72 (50%), Positives = 45/72 (62%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
RYYGG EY D++E LA R+ E + VNVQP+SGS AN VY + P +I+
Sbjct: 61 RYYGGCEYADDVEELAVARAKELFGADH----VNVQPHSGSSANMGVYFATLAPGDKILS 116
Query: 439 LDLPDGGHLTHG 474
LDL GGHL+HG
Sbjct: 117 LDLTHGGHLSHG 128
Score = 53.2 bits (122), Expect = 7e-06
Identities = 28/58 (48%), Positives = 35/58 (60%)
Frame = +2
Query: 101 EADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGTMGG 274
E DPE+ D + E+ RQ L MIASEN S V++ SS L NKY+EG P + GG
Sbjct: 8 EVDPEVADALTGERHRQNDTLAMIASENHVSEAVMEAQSSELTNKYAEGYPGSRYYGG 65
Score = 38.3 bits (85), Expect = 0.23
Identities = 15/43 (34%), Positives = 28/43 (65%)
Frame = +3
Query: 516 FESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDV 644
+E Y+VD ++G +DY+ L E A F+P +I++G + ++V
Sbjct: 138 YEVEQYEVDAETGRLDYEALREHADAFEPDMIVSGFSAYPREV 180
>UniRef50_Q6LHN7 Cluster: Serine hydroxymethyltransferase 2; n=27;
Bacteria|Rep: Serine hydroxymethyltransferase 2 -
Photobacterium profundum (Photobacterium sp. (strain
SS9))
Length = 431
Score = 70.9 bits (166), Expect = 3e-11
Identities = 34/76 (44%), Positives = 51/76 (67%)
Frame = +1
Query: 247 HAHQRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHG 426
+A RYYGG E++DE+E +A R+ + ++ + VNVQP+SG+ AN AV +++P
Sbjct: 69 YAGHRYYGGCEHVDEVEKIAIARAKQLFQCEY----VNVQPHSGAQANGAVMLALLQPGD 124
Query: 427 RIMGLDLPDGGHLTHG 474
I+G+ L GGHLTHG
Sbjct: 125 TILGMSLDAGGHLTHG 140
Score = 46.0 bits (104), Expect = 0.001
Identities = 25/63 (39%), Positives = 36/63 (57%)
Frame = +2
Query: 86 NSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGT 265
++NL + D + I E +RQ +E+IASEN S V+Q +CL NKY+EG +
Sbjct: 15 STNLAQVDGAVNAGIEAELNRQNQQIELIASENIVSKAVMQAQGTCLTNKYAEGYAGHRY 74
Query: 266 MGG 274
GG
Sbjct: 75 YGG 77
>UniRef50_A7R0L6 Cluster: Chromosome undetermined scaffold_311,
whole genome shotgun sequence; n=3; Vitis vinifera|Rep:
Chromosome undetermined scaffold_311, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 340
Score = 69.3 bits (162), Expect = 1e-10
Identities = 37/66 (56%), Positives = 43/66 (65%)
Frame = +2
Query: 77 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPI 256
K LN+ L DPE+ DII EK RQ GLE+I SENFTSV V+Q + S + NKYSEG P
Sbjct: 230 KQLNAPLGVVDPEIADIIELEKARQWKGLELIPSENFTSVSVMQAVGSIMTNKYSEGYPG 289
Query: 257 NGTMGG 274
GG
Sbjct: 290 ARYYGG 295
Score = 50.0 bits (114), Expect = 7e-05
Identities = 21/32 (65%), Positives = 24/32 (75%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWG 354
RYYGGNEYID E L Q R+LEA+RL +WG
Sbjct: 291 RYYGGNEYIDMAESLCQKRALEAFRLDPAKWG 322
>UniRef50_Q8FQR1 Cluster: Serine hydroxymethyltransferase; n=37;
Bacteria|Rep: Serine hydroxymethyltransferase -
Corynebacterium efficiens
Length = 434
Score = 68.9 bits (161), Expect = 1e-10
Identities = 38/73 (52%), Positives = 48/73 (65%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYYGG E +D IE LA++R A L E+ NVQP+SG+ AN AV + +P +IM
Sbjct: 69 RRYYGGCEQVDIIEDLARDR---AKALFDAEFA-NVQPHSGAQANAAVLMTLADPGDKIM 124
Query: 436 GLDLPDGGHLTHG 474
GL L GGHLTHG
Sbjct: 125 GLSLAHGGHLTHG 137
Score = 56.4 bits (130), Expect = 8e-07
Identities = 32/60 (53%), Positives = 34/60 (56%)
Frame = +2
Query: 95 LWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGTMGG 274
L E DPE+ I E RQR LEMIASENF VLQ S L NKY+EG P GG
Sbjct: 15 LSEIDPEVAQAIAGELSRQRDTLEMIASENFVPRSVLQAQGSVLTNKYAEGYPGRRYYGG 74
Score = 34.7 bits (76), Expect = 2.8
Identities = 24/74 (32%), Positives = 39/74 (52%)
Frame = +3
Query: 516 FESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXELN 695
+E Y VDP + L+D D++ E A +P++IIAG + + + + REI +
Sbjct: 147 YEVAAYGVDPDTMLVDMDQVREQAIKEQPKVIIAGWSAYPRHLD-FAAFREI-ADEVGAT 204
Query: 696 LMADXGSRYLGLVA 737
L D + + GLVA
Sbjct: 205 LWVDM-AHFAGLVA 217
>UniRef50_Q183S3 Cluster: Serine hydroxymethyltransferase; n=1;
Clostridium difficile 630|Rep: Serine
hydroxymethyltransferase - Clostridium difficile (strain
630)
Length = 418
Score = 68.5 bits (160), Expect = 2e-10
Identities = 32/72 (44%), Positives = 47/72 (65%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
R+ G+E D++E LA R+ E + + VNVQPYSGS AN+ VY+ I++P+ ++
Sbjct: 60 RFQAGSEEADKLETLAIKRAKEVFGAEH----VNVQPYSGSTANYCVYSSILKPNDTVLS 115
Query: 439 LDLPDGGHLTHG 474
+ L GGHLTHG
Sbjct: 116 MRLDQGGHLTHG 127
Score = 42.7 bits (96), Expect = 0.011
Identities = 24/51 (47%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Frame = +2
Query: 104 ADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLH-NKYSEGMP 253
+DPEL+ I+ E RQ +EMIASE+ VL+ LS C+ NK EG P
Sbjct: 8 SDPELYKIVADELVRQEHNIEMIASESTAPTEVLE-LSGCVFTNKTEEGYP 57
Score = 40.3 bits (90), Expect = 0.056
Identities = 26/72 (36%), Positives = 39/72 (54%)
Frame = +3
Query: 531 YKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXELNLMADX 710
Y VDP +G IDYD L AK +P+LIIAG + + + Y+ ++ ++ M D
Sbjct: 142 YGVDPNTGRIDYDALEAKAKECRPKLIIAGASSYPRLID-YERISKV-AKEVGAYFMVDM 199
Query: 711 GSRYLGLVAGQV 746
+ GLVA +V
Sbjct: 200 -AHVAGLVAAKV 210
>UniRef50_Q057P9 Cluster: Serine hydroxymethyltransferase; n=3;
Gammaproteobacteria|Rep: Serine hydroxymethyltransferase
- Buchnera aphidicola subsp. Cinara cedri
Length = 417
Score = 68.1 bits (159), Expect = 2e-10
Identities = 32/72 (44%), Positives = 50/72 (69%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
R+Y G ID+IE +A R+ + + ++ VNVQP+SGS ANF+V+ +++P+ I+G
Sbjct: 61 RFYNGCNIIDKIEKIAIKRAKKLFNVEY----VNVQPHSGSQANFSVFNALLKPNDIILG 116
Query: 439 LDLPDGGHLTHG 474
++L GGHLTHG
Sbjct: 117 MNLNHGGHLTHG 128
Score = 67.7 bits (158), Expect = 3e-10
Identities = 31/71 (43%), Positives = 47/71 (66%)
Frame = +2
Query: 80 LLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPIN 259
++N+NL DP+++ +I+KEK RQ + + +IASEN+ S +L+ SCL NKY+EG N
Sbjct: 1 MINTNLKNYDPKIWKLIIKEKKRQESYINLIASENYVSSSILEAQGSCLTNKYAEGYIGN 60
Query: 260 GTMGGMNILMK 292
G NI+ K
Sbjct: 61 RFYNGCNIIDK 71
>UniRef50_A6PKY7 Cluster: Serine hydroxymethyltransferase; n=2;
Bacteria|Rep: Serine hydroxymethyltransferase -
Victivallis vadensis ATCC BAA-548
Length = 572
Score = 66.9 bits (156), Expect = 6e-10
Identities = 32/73 (43%), Positives = 47/73 (64%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYY G E++DEIE LA +R + + ++ NVQP++GS AN AVY + +P ++
Sbjct: 218 KRYYNGCEFVDEIEQLAIDRVKKLFGAEA----ANVQPHAGSSANQAVYMALCQPGDTVL 273
Query: 436 GLDLPDGGHLTHG 474
+ L GGHLTHG
Sbjct: 274 SMSLDHGGHLTHG 286
Score = 49.6 bits (113), Expect = 9e-05
Identities = 26/50 (52%), Positives = 30/50 (60%)
Frame = +2
Query: 104 ADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMP 253
ADP + II E RQ G+E+IASENF S V S L NKY+EG P
Sbjct: 167 ADPAVAAIIDHEAKRQADGIELIASENFASCAVRAAQGSVLTNKYAEGYP 216
Score = 34.7 bits (76), Expect = 2.8
Identities = 15/37 (40%), Positives = 25/37 (67%)
Frame = +3
Query: 510 IFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAG 620
+ + +PY V+ ++ +IDYD++ A KPR+IIAG
Sbjct: 294 MLYNIVPYGVNRETEMIDYDEVERLAVENKPRMIIAG 330
>UniRef50_Q62I16 Cluster: Serine hydroxymethyltransferase 1; n=454;
root|Rep: Serine hydroxymethyltransferase 1 -
Burkholderia mallei (Pseudomonas mallei)
Length = 415
Score = 66.5 bits (155), Expect = 8e-10
Identities = 34/73 (46%), Positives = 46/73 (63%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYYGG EY+D +E LA +R + ++ NVQP SGS AN V+ +++P IM
Sbjct: 63 KRYYGGCEYVDIVEQLAIDRVKALFGAEA----ANVQPNSGSQANQGVFFAMLKPGDTIM 118
Query: 436 GLDLPDGGHLTHG 474
G+ L GGHLTHG
Sbjct: 119 GMSLAHGGHLTHG 131
Score = 52.8 bits (121), Expect = 1e-05
Identities = 27/62 (43%), Positives = 36/62 (58%)
Frame = +2
Query: 89 SNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGTM 268
S + DPE++ I +E RQ +E+IASEN+TS V+ S L NKY+EG P
Sbjct: 7 STIANVDPEIWQAIQQENVRQEEHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYY 66
Query: 269 GG 274
GG
Sbjct: 67 GG 68
>UniRef50_Q11NZ7 Cluster: Serine hydroxymethyltransferase; n=6;
Bacteria|Rep: Serine hydroxymethyltransferase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 431
Score = 65.7 bits (153), Expect = 1e-09
Identities = 32/73 (43%), Positives = 46/73 (63%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYYGG + +D++E +A +R +L EW NVQP+SG+ AN A+ + P I+
Sbjct: 62 KRYYGGCQVVDQVEQIAIDR---LKKLFGAEWA-NVQPHSGAQANAAIMIACLNPGDSIL 117
Query: 436 GLDLPDGGHLTHG 474
G DL GGHL+HG
Sbjct: 118 GFDLSHGGHLSHG 130
Score = 65.3 bits (152), Expect = 2e-09
Identities = 29/60 (48%), Positives = 41/60 (68%)
Frame = +2
Query: 107 DPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGTMGGMNIL 286
D ++FD+I KE RQ G+E+IASENFTS V++ + S L NKY+EG+P GG ++
Sbjct: 12 DTQIFDLISKEAHRQEEGIELIASENFTSKQVMEAMGSVLTNKYAEGLPGKRYYGGCQVV 71
Score = 37.1 bits (82), Expect = 0.53
Identities = 26/75 (34%), Positives = 42/75 (56%)
Frame = +3
Query: 513 FFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXEL 692
+F++ Y V+ +SGLI+ D + TA KP++II G +++D Y R+I +
Sbjct: 139 YFKAHFYGVEKESGLINMDIVEATALKVKPKMIICGASAYSRDWD-YARFRKIADSVGAI 197
Query: 693 NLMADXGSRYLGLVA 737
L+AD S GL+A
Sbjct: 198 -LLADI-SHPAGLIA 210
>UniRef50_Q6G3L3 Cluster: Serine hydroxymethyltransferase; n=163;
cellular organisms|Rep: Serine hydroxymethyltransferase
- Bartonella henselae (Rochalimaea henselae)
Length = 437
Score = 63.7 bits (148), Expect = 5e-09
Identities = 35/73 (47%), Positives = 46/73 (63%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYYGG +++D IE LA R A +L ++ NVQ SGS N AV+ +++P M
Sbjct: 71 KRYYGGCQFVDVIENLAIER---AKKLFGADFA-NVQANSGSQMNQAVFLALLKPGDTFM 126
Query: 436 GLDLPDGGHLTHG 474
GLDL GGHLTHG
Sbjct: 127 GLDLNSGGHLTHG 139
Score = 54.4 bits (125), Expect = 3e-06
Identities = 29/66 (43%), Positives = 37/66 (56%)
Frame = +2
Query: 77 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPI 256
+ N NL D +FD I E +RQ+ +E+IASEN S VL+ S L NKY+EG P
Sbjct: 11 RFFNDNLQTVDVAIFDAIRGEFERQQHEIELIASENIVSRAVLEAQGSVLTNKYAEGYPG 70
Query: 257 NGTMGG 274
GG
Sbjct: 71 KRYYGG 76
Score = 37.9 bits (84), Expect = 0.30
Identities = 28/78 (35%), Positives = 43/78 (55%)
Frame = +3
Query: 513 FFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXEL 692
+F+S+ Y V + L+D + + AK KP+LIIAG +++ + +K REI +
Sbjct: 148 WFKSISYGVRKEDQLLDMEAVERLAKEHKPKLIIAGGSAYSR-LWDWKKFREI-ADEIGA 205
Query: 693 NLMADXGSRYLGLVAGQV 746
L+ D S GLVAG V
Sbjct: 206 YLLVDM-SHIAGLVAGGV 222
>UniRef50_Q05FV9 Cluster: Serine hydroxymethyltransferase; n=1;
Candidatus Carsonella ruddii PV|Rep: Serine
hydroxymethyltransferase - Carsonella ruddii (strain PV)
Length = 398
Score = 60.1 bits (139), Expect = 7e-08
Identities = 31/77 (40%), Positives = 45/77 (58%)
Frame = +1
Query: 247 HAHQRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHG 426
+ +QRYY G ++ D IE +E L + + NVQ +SGS ANF+ ++ +
Sbjct: 50 YPNQRYYSGCKFFDIIE---NKTIIETQNLFNSNFA-NVQSHSGSQANFSGIQSLINKNE 105
Query: 427 RIMGLDLPDGGHLTHGF 477
+I+ LDL GGHLTHGF
Sbjct: 106 KILSLDLKSGGHLTHGF 122
Score = 43.6 bits (98), Expect = 0.006
Identities = 20/46 (43%), Positives = 29/46 (63%)
Frame = +2
Query: 116 LFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMP 253
+ + I E +Q L +IASEN++S+ + SSCL NKY+EG P
Sbjct: 6 ILNFIKIESKKQEKTLNLIASENYSSITSILYSSSCLTNKYTEGYP 51
>UniRef50_Q9UMD0 Cluster: 14 kDa protein; n=2; Homo sapiens|Rep: 14
kDa protein - Homo sapiens (Human)
Length = 129
Score = 55.2 bits (127), Expect = 2e-06
Identities = 22/37 (59%), Positives = 29/37 (78%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQP 369
RYYGG E+IDE+E L Q R+L+AY+L + WGV+V P
Sbjct: 65 RYYGGTEFIDELETLCQKRALQAYKLDPQCWGVDVHP 101
>UniRef50_Q12RK5 Cluster: Glycine hydroxymethyltransferase; n=2;
Gammaproteobacteria|Rep: Glycine
hydroxymethyltransferase - Shewanella denitrificans
(strain OS217 / ATCC BAA-1090 / DSM 15013)
Length = 451
Score = 54.4 bits (125), Expect = 3e-06
Identities = 27/73 (36%), Positives = 43/73 (58%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RY+ G E +D +E LA +R+ + + + VQ +S S AN+ V + +EP ++
Sbjct: 76 RRYHAGCENVDLVESLAISRARQLFDAQY----AGVQSHSASSANYQVLSAFLEPGDTLL 131
Query: 436 GLDLPDGGHLTHG 474
G+ L GGHLTHG
Sbjct: 132 GMSLDHGGHLTHG 144
Score = 41.9 bits (94), Expect = 0.018
Identities = 28/75 (37%), Positives = 45/75 (60%)
Frame = +3
Query: 513 FFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXEL 692
+++++ Y + GLIDYD++ + A+L KPRLII G +++ V ++ REI +
Sbjct: 153 YYQAIGYGTTSQ-GLIDYDEVLKLARLHKPRLIICGATAYSRIVD-FERFREIADEVGAI 210
Query: 693 NLMADXGSRYLGLVA 737
L+AD S GLVA
Sbjct: 211 -LLADI-SHIAGLVA 223
>UniRef50_Q8TZ19 Cluster: Serine hydroxymethyltransferase; n=8;
Euryarchaeota|Rep: Serine hydroxymethyltransferase -
Methanopyrus kandleri
Length = 428
Score = 54.0 bits (124), Expect = 4e-06
Identities = 28/72 (38%), Positives = 39/72 (54%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+R Y G EYIDE+E+ + E + + NVQP SG AN A + EP I+
Sbjct: 57 ERLYEGCEYIDEVELACVRLAKELFGAEH----ANVQPTSGVVANLAALFALTEPGDTIL 112
Query: 436 GLDLPDGGHLTH 471
GL + GGH++H
Sbjct: 113 GLRISHGGHISH 124
>UniRef50_Q883D8 Cluster: Serine hydroxymethyltransferase, putative;
n=1; Pseudomonas syringae pv. tomato|Rep: Serine
hydroxymethyltransferase, putative - Pseudomonas
syringae pv. tomato
Length = 364
Score = 52.4 bits (120), Expect = 1e-05
Identities = 31/75 (41%), Positives = 45/75 (60%)
Frame = +1
Query: 250 AHQRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGR 429
A +R + G + DEIE A +L A R+ + E N+QP+S S AN +VY ++EP
Sbjct: 2 AGKRPFAGARFHDEIERTA---ALIACRVFNAEHA-NLQPHSCSQANQSVYHALLEPGDN 57
Query: 430 IMGLDLPDGGHLTHG 474
++ L+ GGHLTHG
Sbjct: 58 VLALNFKAGGHLTHG 72
Score = 38.3 bits (85), Expect = 0.23
Identities = 28/76 (36%), Positives = 39/76 (51%)
Frame = +3
Query: 510 IFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXE 689
+FF Y VD + LIDYD + A FKP+LI+ G + + + + REI +
Sbjct: 80 MFFNFRHYGVDEATDLIDYDLAEQDAIRFKPKLIVCGSSSYPR-LFDARRLREISDKVGA 138
Query: 690 LNLMADXGSRYLGLVA 737
L LM D S GL+A
Sbjct: 139 L-LMFDL-SHEAGLIA 152
>UniRef50_O29406 Cluster: Serine hydroxymethyltransferase; n=6;
Euryarchaeota|Rep: Serine hydroxymethyltransferase -
Archaeoglobus fulgidus
Length = 438
Score = 52.0 bits (119), Expect = 2e-05
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+R+Y G +Y+D+IE +A +E R E NVQP SG AN A + + IM
Sbjct: 70 ERFYEGCKYVDQIESMA----IELTRKIFEAEHANVQPISGVVANLAAFFALTNVGDTIM 125
Query: 436 GLDLPDGGHLTH 471
+ +P GGH++H
Sbjct: 126 SISVPCGGHISH 137
Score = 37.9 bits (84), Expect = 0.30
Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Frame = +2
Query: 71 SAKLLNSNLWEADP-ELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEG 247
S K +S + +P ++F II R + +IASEN TS+ V +C S L ++Y+EG
Sbjct: 7 SLKYFSSVAEDMNPSDVFQIIEGHTKLMRDSIPLIASENLTSLSVRRCYVSDLGHRYAEG 66
>UniRef50_Q5CM83 Cluster: Serine hydroxymethyltransferase 2; n=2;
Cryptosporidium|Rep: Serine hydroxymethyltransferase 2 -
Cryptosporidium hominis
Length = 438
Score = 50.8 bits (116), Expect = 4e-05
Identities = 28/64 (43%), Positives = 36/64 (56%)
Frame = +2
Query: 101 EADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGTMGGMN 280
E+D ELF+II KEKD Q + L + EN + L S L NKYSEG P GG +
Sbjct: 6 ESDQELFNIINKEKDFQNSHLNLHPKENVMINAARKVLGSILTNKYSEGFPGTRYYGGTH 65
Query: 281 ILMK 292
++ K
Sbjct: 66 VIDK 69
Score = 49.2 bits (112), Expect = 1e-04
Identities = 25/62 (40%), Positives = 36/62 (58%), Gaps = 3/62 (4%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRL---KSEEWGVNVQPYSGSPANFAVYTGIVEPHGR 429
RYYGG ID+IE L +R + +L ++EW N+Q YSGS A A+ G++ R
Sbjct: 59 RYYGGTHVIDKIETLCASRLKQFLKLDKKSNDEWLFNIQCYSGSHAELAICMGLLNKGDR 118
Query: 430 IM 435
I+
Sbjct: 119 IL 120
>UniRef50_Q1W396 Cluster: Glycine hydroxymethyltransferase; n=1;
Striga asiatica|Rep: Glycine hydroxymethyltransferase -
Striga asiatica (Asiatic witchweed) (Striga lutea)
Length = 125
Score = 48.4 bits (110), Expect = 2e-04
Identities = 24/47 (51%), Positives = 33/47 (70%)
Frame = +2
Query: 74 AKLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCL 214
+ ++ L EADPE+ II KEK+RQ LE+IASENFTS V++ +
Sbjct: 78 SSFVDYGLSEADPEVHSIIDKEKNRQFRSLELIASENFTSRAVMEAV 124
>UniRef50_O83349 Cluster: Serine hydroxymethyltransferase; n=18;
Bacteria|Rep: Serine hydroxymethyltransferase -
Treponema pallidum
Length = 574
Score = 44.8 bits (101), Expect = 0.003
Identities = 26/77 (33%), Positives = 45/77 (58%)
Frame = +3
Query: 516 FESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXELN 695
F + Y VD +GL+DY + AK +P +++AG+ + + ++ ++ REI + +
Sbjct: 195 FRVVSYAVDRDTGLLDYAAIEAQAKRERPLILLAGYSAYPRSIN-FRIFREIADKVGAV- 252
Query: 696 LMADXGSRYLGLVAGQV 746
LMAD + + GLVAG V
Sbjct: 253 LMADM-AHFAGLVAGGV 268
Score = 44.0 bits (99), Expect = 0.005
Identities = 21/55 (38%), Positives = 37/55 (67%)
Frame = +2
Query: 110 PELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPINGTMGG 274
P++ IV+E QR+ +++IASEN++S+ V +++ L +KY+EG P + GG
Sbjct: 37 PQIASDIVQELIDQRSYVKLIASENYSSLAVQAAMANLLTDKYAEGFPHHRYYGG 91
Score = 36.7 bits (81), Expect(2) = 3e-04
Identities = 22/54 (40%), Positives = 29/54 (53%)
Frame = +1
Query: 253 HQRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIV 414
H RYYGG + +D IE A + EA L E VQP+SG+ AN + I+
Sbjct: 85 HHRYYGGCQNVDSIESAA---AAEACALFGAEHAY-VQPHSGADANLVAFWAIL 134
Score = 30.7 bits (66), Expect(2) = 3e-04
Identities = 11/17 (64%), Positives = 14/17 (82%)
Frame = +1
Query: 427 RIMGLDLPDGGHLTHGF 477
++MGLD GGHLTHG+
Sbjct: 170 KLMGLDYFSGGHLTHGY 186
>UniRef50_A0RYP2 Cluster: Glycine/serine hydroxymethyltransferase;
n=2; Thermoprotei|Rep: Glycine/serine
hydroxymethyltransferase - Cenarchaeum symbiosum
Length = 441
Score = 46.0 bits (104), Expect = 0.001
Identities = 22/73 (30%), Positives = 39/73 (53%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+R Y G YID +E + + ++ + + V+P SG AN A+Y+ +P ++
Sbjct: 61 ERVYAGCTYIDMVETECMKLAKKLFKAEFAD----VRPVSGVVANLAIYSAFSDPGDVMI 116
Query: 436 GLDLPDGGHLTHG 474
+P GGH++HG
Sbjct: 117 APSIPAGGHISHG 129
>UniRef50_Q8ZYF9 Cluster: Serine hydroxymethyltransferase; n=5;
Thermoproteaceae|Rep: Serine hydroxymethyltransferase -
Pyrobaculum aerophilum
Length = 430
Score = 46.0 bits (104), Expect = 0.001
Identities = 25/71 (35%), Positives = 37/71 (52%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
RYY G +Y+D +E R + K V+V+P SG+ AN A Y +V G +
Sbjct: 58 RYYQGTKYVDILEDSLSKRFAKVLDAKF----VDVRPISGTIANLATYHALVPEGGIVAS 113
Query: 439 LDLPDGGHLTH 471
L + GGH++H
Sbjct: 114 LPVKYGGHISH 124
>UniRef50_Q9PJW0 Cluster: Serine hydroxymethyltransferase; n=8;
Chlamydiaceae|Rep: Serine hydroxymethyltransferase -
Chlamydia muridarum
Length = 497
Score = 44.8 bits (101), Expect = 0.003
Identities = 23/54 (42%), Positives = 34/54 (62%)
Frame = +2
Query: 92 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMP 253
+L + P + IV+E QR+ L+MIASENF+S+ V + + L +KY EG P
Sbjct: 31 HLLHSFPSIGQSIVQELKSQRSRLKMIASENFSSLSVQLAMGNLLTDKYCEGSP 84
Score = 37.9 bits (84), Expect = 0.30
Identities = 23/74 (31%), Positives = 44/74 (59%)
Frame = +3
Query: 525 MPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXELNLMA 704
+PY+V+ + L DYD +A+ AK +P ++IAG+ +++ ++ + ++I + L
Sbjct: 199 LPYEVNLDTELFDYDVIAKIAKEHRPTVLIAGYSSYSRRLN-FATLKQIAEDCGAV-LWV 256
Query: 705 DXGSRYLGLVAGQV 746
D + + GLVAG V
Sbjct: 257 DM-AHFAGLVAGGV 269
>UniRef50_Q9TSA5 Cluster: Serine hydroxymethyltransferase; n=1; Ovis
aries|Rep: Serine hydroxymethyltransferase - Ovis aries
(Sheep)
Length = 150
Score = 43.2 bits (97), Expect = 0.008
Identities = 18/34 (52%), Positives = 26/34 (76%)
Frame = +3
Query: 537 VDPKSGLIDYDKLAETAKLFKPRLIIAGHELFTQ 638
V+P +G IDYD+L E A+LF P+LIIAG +++
Sbjct: 54 VNPDTGYIDYDQLEENARLFHPKLIIAGTSCYSR 87
Score = 33.5 bits (73), Expect = 6.5
Identities = 16/26 (61%), Positives = 17/26 (65%)
Frame = +1
Query: 388 NFAVYTGIVEPHGRIMGLDLPDGGHL 465
NFA P RIMGLDLPDGGH+
Sbjct: 29 NFASRYSEGYPGQRIMGLDLPDGGHV 54
>UniRef50_Q9YAH7 Cluster: Serine hydroxymethyltransferase; n=9;
Archaea|Rep: Serine hydroxymethyltransferase - Aeropyrum
pernix
Length = 439
Score = 40.7 bits (91), Expect = 0.043
Identities = 24/75 (32%), Positives = 40/75 (53%)
Frame = +1
Query: 256 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 435
+RYY G YIDE+E+L L + + V ++P SG+ AN +V+ + EP + +
Sbjct: 64 KRYYQGTRYIDELEVLTGE--LMGSMMGTNL--VELRPVSGTIANASVFRVLAEPGDKAV 119
Query: 436 GLDLPDGGHLTHGFF 480
+ G H++H F
Sbjct: 120 IAPVQAGAHVSHTKF 134
>UniRef50_A6TST7 Cluster: Glycine hydroxymethyltransferase; n=1;
Alkaliphilus metalliredigens QYMF|Rep: Glycine
hydroxymethyltransferase - Alkaliphilus metalliredigens
QYMF
Length = 368
Score = 39.9 bits (89), Expect = 0.075
Identities = 21/68 (30%), Positives = 35/68 (51%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
R Y GN+YI E E+ + ++ K V+++P G A +V G++EP ++
Sbjct: 20 REYTGNQYIHEFEMATHELVKDIFKAKY----VDLRPIGGHMAGMSVVLGMLEPGDLVIE 75
Query: 439 LDLPDGGH 462
+ L D GH
Sbjct: 76 VSLSDWGH 83
>UniRef50_Q9HI38 Cluster: Serine hydroxymethyltransferase; n=5;
Thermoplasmatales|Rep: Serine hydroxymethyltransferase -
Thermoplasma acidophilum
Length = 426
Score = 38.3 bits (85), Expect = 0.23
Identities = 23/76 (30%), Positives = 33/76 (43%)
Frame = +1
Query: 253 HQRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRI 432
H RYY GN Y+D IE + +R + +P SG+ AN A + P +
Sbjct: 55 HHRYYQGNYYVDLIEDRTNELLSKLFRTSQ----TDPRPISGTNANSAAIYALAGPGDLV 110
Query: 433 MGLDLPDGGHLTHGFF 480
L GGH++ F
Sbjct: 111 ATPSLSGGGHISAAEF 126
>UniRef50_Q6L0Q9 Cluster: Serine hydroxymethyltransferase; n=1;
Picrophilus torridus|Rep: Serine
hydroxymethyltransferase - Picrophilus torridus
Length = 377
Score = 37.9 bits (84), Expect = 0.30
Identities = 24/66 (36%), Positives = 37/66 (56%)
Frame = +3
Query: 546 KSGLIDYDKLAETAKLFKPRLIIAGHELFTQDVSIYKXXREIRRRQXELNLMADXGSRYL 725
KSG IDYD + + A+ +P +II G FT I K ++ R+ + ++ D S L
Sbjct: 132 KSGSIDYDAMEKIARSERPSVIILGQSEFTMPYDI-KRVYDL-SREIDSRIIYD-ASHVL 188
Query: 726 GLVAGQ 743
GL+AG+
Sbjct: 189 GLIAGR 194
>UniRef50_Q5DH62 Cluster: SJCHGC03592 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03592 protein - Schistosoma
japonicum (Blood fluke)
Length = 107
Score = 36.7 bits (81), Expect = 0.70
Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Frame = +2
Query: 35 FAAKRYISSTKMSAKLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASE-NFTSVPVLQC 211
F++ S +AK L D EL+++I KE+ RQ++ L +IASE F + P C
Sbjct: 14 FSSNSSSSRVSTAAKCATGGLQTKDTELWELIQKERYRQKSSLTLIASEVRFFTCP---C 70
Query: 212 LSSCLHNKYS 241
L+ K S
Sbjct: 71 YFRTLYRKVS 80
>UniRef50_Q28QL6 Cluster: Glycine hydroxymethyltransferase; n=7;
Rhodobacteraceae|Rep: Glycine hydroxymethyltransferase -
Jannaschia sp. (strain CCS1)
Length = 445
Score = 35.5 bits (78), Expect = 1.6
Identities = 20/71 (28%), Positives = 35/71 (49%)
Frame = +1
Query: 259 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMG 438
+Y G E ++E E++A + E +R + E ++ SG+ AN + +P I+
Sbjct: 85 KYEMGLEAVEEAEVIAAELAAEVFRARFAE----IRVASGAMANLYAFMATCQPGDTIIV 140
Query: 439 LDLPDGGHLTH 471
GGH+TH
Sbjct: 141 PPASIGGHVTH 151
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 804,299,368
Number of Sequences: 1657284
Number of extensions: 16650546
Number of successful extensions: 37521
Number of sequences better than 10.0: 51
Number of HSP's better than 10.0 without gapping: 36350
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37497
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 70377768045
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -