BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= ps4M0206.Seq (840 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q1RKZ5 Cluster: IP15551p; n=1; Drosophila melanogaster|... 145 1e-33 UniRef50_P05990 Cluster: CAD protein (Protein rudimentary) [Incl... 145 1e-33 UniRef50_A7T4N0 Cluster: Predicted protein; n=1; Nematostella ve... 129 7e-29 UniRef50_P27708 Cluster: CAD protein [Includes: Glutamine-depend... 123 5e-27 UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspar... 120 3e-26 UniRef50_Q4SZL4 Cluster: Chromosome 14 SCAF11586, whole genome s... 120 6e-26 UniRef50_Q8U4A0 Cluster: Dihydroorotase; n=5; Thermococcaceae|Re... 77 4e-13 UniRef50_A6RFE1 Cluster: Bifunctional pyrimidine biosynthesis pr... 75 2e-12 UniRef50_A2SQD3 Cluster: Dihydroorotase, multifunctional complex... 70 6e-11 UniRef50_A1RZC7 Cluster: Dihydroorotase, multifunctional complex... 67 6e-10 UniRef50_Q8YUN6 Cluster: Dihydroorotase; n=4; Bacteria|Rep: Dihy... 66 1e-09 UniRef50_Q0W790 Cluster: Dihydroorotase; n=1; uncultured methano... 65 2e-09 UniRef50_UPI0000DAE5C6 Cluster: hypothetical protein Rgryl_01000... 64 3e-09 UniRef50_Q4JN07 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihy... 64 4e-09 UniRef50_Q58885 Cluster: Dihydroorotase; n=6; Methanococcales|Re... 63 7e-09 UniRef50_Q7NF57 Cluster: Dihydroorotase; n=12; Cyanobacteria|Rep... 63 1e-08 UniRef50_Q8ZZC7 Cluster: Dihydroorotase; n=4; Pyrobaculum|Rep: D... 62 1e-08 UniRef50_O28034 Cluster: Dihydroorotase; n=1; Archaeoglobus fulg... 61 3e-08 UniRef50_A0B872 Cluster: Dihydroorotase, multifunctional complex... 61 4e-08 UniRef50_Q9HMH9 Cluster: Dihydroorotase; n=6; Halobacteriaceae|R... 60 7e-08 UniRef50_Q2FLR3 Cluster: Dihydroorotase; n=3; Methanomicrobiales... 59 1e-07 UniRef50_P77884 Cluster: Dihydroorotase; n=25; Bacilli|Rep: Dihy... 58 3e-07 UniRef50_Q30X37 Cluster: Dihydroorotase, multifunctional complex... 58 4e-07 UniRef50_A3ZRV3 Cluster: Dihydroorotase; n=1; Blastopirellula ma... 57 5e-07 UniRef50_Q28JR7 Cluster: Allantoinase; n=1; Jannaschia sp. CCS1|... 57 6e-07 UniRef50_Q2NHZ6 Cluster: Dihydroorotase; n=1; Methanosphaera sta... 57 6e-07 UniRef50_Q5HGN1 Cluster: Dihydroorotase; n=14; Bacillales|Rep: D... 57 6e-07 UniRef50_A5ULX4 Cluster: Dihydroorotase, PyrC; n=1; Methanobrevi... 56 8e-07 UniRef50_A5UX77 Cluster: Dihydroorotase, multifunctional complex... 56 1e-06 UniRef50_Q984Y5 Cluster: Dihydroorotase; n=50; cellular organism... 56 1e-06 UniRef50_Q73ID8 Cluster: Dihydroorotase; n=15; Rickettsiales|Rep... 55 2e-06 UniRef50_Q5FPJ5 Cluster: Dihydroorotase; n=4; Proteobacteria|Rep... 55 2e-06 UniRef50_Q4QEW1 Cluster: Dihydroorotase, putative; n=9; Trypanos... 55 2e-06 UniRef50_Q74DP4 Cluster: Dihydroorotase, multifunctional complex... 55 3e-06 UniRef50_P25995 Cluster: Dihydroorotase; n=41; Bacteria|Rep: Dih... 55 3e-06 UniRef50_Q9PEP0 Cluster: Dihydroorotase; n=54; cellular organism... 54 3e-06 UniRef50_Q3AC01 Cluster: Dihydroorotase; n=1; Carboxydothermus h... 54 3e-06 UniRef50_Q2RGZ6 Cluster: D-hydantoinase; n=1; Moorella thermoace... 54 4e-06 UniRef50_P07259 Cluster: Protein URA1 [Includes: Glutamine-depen... 54 4e-06 UniRef50_Q0LDY3 Cluster: Dihydroorotase; n=2; Chloroflexi (class... 54 6e-06 UniRef50_A4GJR5 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihy... 54 6e-06 UniRef50_A4ECL5 Cluster: Dihydroorotase; n=1; Collinsella aerofa... 54 6e-06 UniRef50_Q8XL61 Cluster: Dihydroorotase; n=12; Bacteria|Rep: Dih... 53 8e-06 UniRef50_Q89PZ7 Cluster: D-hydantoinase; n=5; Alphaproteobacteri... 53 8e-06 UniRef50_Q6U5R7 Cluster: PyrC; n=6; Gammaproteobacteria|Rep: Pyr... 53 8e-06 UniRef50_Q1VNG2 Cluster: Dihydroorotase; n=2; Psychroflexus torq... 53 8e-06 UniRef50_A5NZP0 Cluster: Dihydropyrimidinase; n=5; Proteobacteri... 53 8e-06 UniRef50_Q7NEQ6 Cluster: Dihydroorotase; n=1; Gloeobacter violac... 53 1e-05 UniRef50_Q8KDK5 Cluster: Dihydroorotase; n=10; Chlorobiaceae|Rep... 53 1e-05 UniRef50_Q9KAH8 Cluster: Allantoinase; n=1; Bacillus halodurans|... 52 1e-05 UniRef50_Q8AB61 Cluster: Dihydroorotase; n=3; Bacteroides|Rep: D... 52 1e-05 UniRef50_Q2KXE6 Cluster: D-hydantoinase; n=2; Proteobacteria|Rep... 52 1e-05 UniRef50_A4XKT2 Cluster: Dihydroorotase, multifunctional complex... 52 1e-05 UniRef50_O27199 Cluster: Dihydroorotase; n=2; Methanothermobacte... 52 1e-05 UniRef50_Q0UHH4 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05 UniRef50_O66990 Cluster: Dihydroorotase; n=1; Aquifex aeolicus|R... 52 2e-05 UniRef50_A6TVS5 Cluster: Dihydroorotase; n=8; Clostridiales|Rep:... 51 3e-05 UniRef50_A7D6W5 Cluster: Amidohydrolase; n=1; Halorubrum lacuspr... 51 3e-05 UniRef50_A5DGE8 Cluster: Putative uncharacterized protein; n=1; ... 51 4e-05 UniRef50_Q6AF87 Cluster: Dihydroorotase; n=9; Actinobacteria (cl... 51 4e-05 UniRef50_Q1M4X9 Cluster: Putative D-hydantoinase; n=1; Rhizobium... 50 6e-05 UniRef50_Q18ZN3 Cluster: Dihydroorotase; n=3; Clostridiales|Rep:... 50 6e-05 UniRef50_Q9RVC3 Cluster: Dihydroorotase; n=5; Deinococci|Rep: Di... 50 6e-05 UniRef50_Q3AEA1 Cluster: Allantoinase; n=3; Clostridiales|Rep: A... 50 7e-05 UniRef50_A6P0Z6 Cluster: Dihydroorotase; n=1; Bacteroides capill... 50 7e-05 UniRef50_A3H6L5 Cluster: Amidohydrolase; n=1; Caldivirga maquili... 50 7e-05 UniRef50_Q8R9R6 Cluster: Dihydroorotase; n=5; Clostridia|Rep: Di... 50 7e-05 UniRef50_A7CWA7 Cluster: Dihydroorotase, multifunctional complex... 50 1e-04 UniRef50_Q97LN7 Cluster: Dihydroorotase; n=4; Clostridiales|Rep:... 50 1e-04 UniRef50_A4GK51 Cluster: Dihydroorotase; n=1; uncultured marine ... 49 1e-04 UniRef50_A0RQX7 Cluster: Dihydroorotase; n=4; Campylobacter|Rep:... 49 1e-04 UniRef50_UPI00015BB20A Cluster: dihydroorotase; n=1; Ignicoccus ... 49 2e-04 UniRef50_Q8F061 Cluster: Dihydroorotase; n=5; Bacteria|Rep: Dihy... 49 2e-04 UniRef50_Q83HU2 Cluster: Dihydroorotase; n=2; Tropheryma whipple... 49 2e-04 UniRef50_Q765R4 Cluster: Allantoinase; n=1; Klebsiella pneumonia... 49 2e-04 UniRef50_Q18S75 Cluster: Amidohydrolase; n=2; Desulfitobacterium... 49 2e-04 UniRef50_A6R6Y6 Cluster: Allantoinase; n=1; Ajellomyces capsulat... 49 2e-04 UniRef50_Q97QN4 Cluster: Dihydroorotase; n=47; Firmicutes|Rep: D... 49 2e-04 UniRef50_Q8TSA6 Cluster: Dihydroorotase; n=4; Methanosarcinaceae... 49 2e-04 UniRef50_Q64RK7 Cluster: Dihydroorotase; n=6; Bacteroidales|Rep:... 48 2e-04 UniRef50_Q1M4Y4 Cluster: Putative dihydroorotase; n=1; Rhizobium... 48 2e-04 UniRef50_A5ZPT0 Cluster: Dihydroorotase; n=1; Ruminococcus obeum... 48 2e-04 UniRef50_Q44184 Cluster: D-hydantoinase; n=5; Proteobacteria|Rep... 48 2e-04 UniRef50_Q1Q402 Cluster: Similar to dihydroorotase; n=1; Candida... 48 3e-04 UniRef50_P77671 Cluster: Allantoinase; n=25; Bacteria|Rep: Allan... 48 4e-04 UniRef50_A5NXH5 Cluster: Allantoinase; n=2; Proteobacteria|Rep: ... 47 5e-04 UniRef50_A0L3T8 Cluster: Dihydroorotase, multifunctional complex... 47 7e-04 UniRef50_P81006 Cluster: Non-ATP-dependent L-selective hydantoin... 47 7e-04 UniRef50_O69809 Cluster: D-hydantoinase; n=4; Bacteria|Rep: D-hy... 47 7e-04 UniRef50_O32137 Cluster: Allantoinase; n=1; Bacillus subtilis|Re... 47 7e-04 UniRef50_Q831D1 Cluster: D-hydantoinase; n=6; Firmicutes|Rep: D-... 46 9e-04 UniRef50_A4M847 Cluster: Dihydropyrimidinase; n=1; Petrotoga mob... 46 9e-04 UniRef50_Q6A916 Cluster: Dihydroorotase; n=1; Propionibacterium ... 46 0.001 UniRef50_Q3ZYB9 Cluster: Dihydroorotase, multifunctional complex... 46 0.001 UniRef50_A7HCE8 Cluster: Dihydroorotase, multifunctional complex... 46 0.001 UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic amido... 46 0.001 UniRef50_A2R282 Cluster: Contig An13c0120, complete genome; n=3;... 46 0.001 UniRef50_A3DKS9 Cluster: Amidohydrolase; n=1; Staphylothermus ma... 46 0.001 UniRef50_Q2JER9 Cluster: Allantoinase; n=5; Bacteria|Rep: Allant... 46 0.002 UniRef50_A6LUT2 Cluster: Dihydropyrimidinase; n=3; cellular orga... 46 0.002 UniRef50_Q9RKU5 Cluster: Probable allantoinase; n=8; Actinomycet... 46 0.002 UniRef50_UPI0001597BA8 Cluster: PucH; n=1; Bacillus amyloliquefa... 45 0.002 UniRef50_Q67Q00 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihy... 45 0.002 UniRef50_A3ESI6 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihy... 45 0.002 UniRef50_A1SH63 Cluster: Dihydropyrimidinase; n=1; Nocardioides ... 45 0.002 UniRef50_UPI00015BD532 Cluster: UPI00015BD532 related cluster; n... 45 0.003 UniRef50_Q89Q35 Cluster: D-hydantoinase; n=20; Proteobacteria|Re... 45 0.003 UniRef50_A6E6Y3 Cluster: Dihydroorotase; n=1; Pedobacter sp. BAL... 45 0.003 UniRef50_Q5KFL1 Cluster: Dihydropyrimidinase, putative; n=2; Fil... 45 0.003 UniRef50_UPI000038E4AB Cluster: hypothetical protein Faci_030004... 44 0.004 UniRef50_Q89K18 Cluster: Blr5100 protein; n=43; Alphaproteobacte... 44 0.004 UniRef50_A6PU21 Cluster: Dihydroorotase, multifunctional complex... 44 0.004 UniRef50_Q8NQ39 Cluster: Dihydroorotase; n=35; Actinomycetales|R... 44 0.004 UniRef50_Q1IJ01 Cluster: Dihydroorotase, multifunctional complex... 44 0.005 UniRef50_Q18WQ5 Cluster: Dihydroorotase, multifunctional complex... 44 0.005 UniRef50_A2U746 Cluster: Dihydropyrimidinase; n=3; Bacillus|Rep:... 44 0.005 UniRef50_Q9P903 Cluster: Dihydropyrimidinase; n=2; Saccharomycet... 44 0.005 UniRef50_A3LNF2 Cluster: Allantoinase; n=2; Saccharomycetales|Re... 44 0.005 UniRef50_A1C896 Cluster: Aminohydrolase; n=6; cellular organisms... 44 0.005 UniRef50_Q73KW0 Cluster: Dihydroorotase, putative; n=1; Treponem... 44 0.006 UniRef50_A5DY43 Cluster: Putative uncharacterized protein; n=1; ... 44 0.006 UniRef50_Q1VPD0 Cluster: Dihydroorotase; n=11; Bacteroidetes|Rep... 43 0.008 UniRef50_Q9RV76 Cluster: Probable allantoinase; n=4; Bacteria|Re... 43 0.008 UniRef50_Q2SMZ8 Cluster: Dihydroorotase and related cyclic amido... 43 0.011 UniRef50_A4EA66 Cluster: Putative uncharacterized protein; n=1; ... 43 0.011 UniRef50_A4C048 Cluster: Amidohydrolase family, putative; n=10; ... 43 0.011 UniRef50_Q64E81 Cluster: Dihydroorotase; n=1; uncultured archaeo... 43 0.011 UniRef50_A0RTM1 Cluster: Dihydroorotase; n=2; Thermoprotei|Rep: ... 43 0.011 UniRef50_Q51551 Cluster: Dihydroorotase-like protein; n=14; Gamm... 43 0.011 UniRef50_Q9WYH0 Cluster: Dihydroorotase; n=4; Thermotogaceae|Rep... 43 0.011 UniRef50_Q8YRV3 Cluster: Dihydroorotase; n=8; Cyanobacteria|Rep:... 42 0.015 UniRef50_Q5FRG9 Cluster: Dihydroorotase; n=4; Rhodospirillales|R... 42 0.015 UniRef50_A7B6D5 Cluster: Putative uncharacterized protein; n=1; ... 42 0.015 UniRef50_Q4AGB4 Cluster: Dihydropyrimidinase; n=1; Chlorobium ph... 42 0.025 UniRef50_Q6CUK0 Cluster: Similar to sp|P32375 Saccharomyces cere... 42 0.025 UniRef50_A1CFB0 Cluster: Allantoinase Dal1, putative; n=11; Pezi... 42 0.025 UniRef50_A2BJ21 Cluster: Dihydroorotase; n=1; Hyperthermus butyl... 42 0.025 UniRef50_Q2S0H8 Cluster: Dihydroorotase; n=1; Salinibacter ruber... 41 0.034 UniRef50_Q26E93 Cluster: Dihydroorotase; n=1; Flavobacteria bact... 41 0.034 UniRef50_Q9UX05 Cluster: Dihydroorotase; n=5; Sulfolobaceae|Rep:... 41 0.034 UniRef50_Q930B0 Cluster: Allantoinase, putative; n=1; Sinorhizob... 41 0.045 UniRef50_A6DRU9 Cluster: Dihydroorotase; n=1; Lentisphaera arane... 41 0.045 UniRef50_Q6C0N2 Cluster: Similar to sp|P32375 Saccharomyces cere... 41 0.045 UniRef50_Q8TXX9 Cluster: Dihydroorotase; n=1; Methanopyrus kandl... 41 0.045 UniRef50_Q1AVY7 Cluster: Dihydroorotase; n=1; Rubrobacter xylano... 40 0.059 UniRef50_Q4FLQ3 Cluster: Dihydroorotase; n=2; Candidatus Pelagib... 40 0.078 UniRef50_Q18S74 Cluster: Amidohydrolase; n=2; Desulfitobacterium... 40 0.078 UniRef50_A6CS57 Cluster: Dihydropyrimidinase; n=1; Bacillus sp. ... 40 0.078 UniRef50_Q6KZ43 Cluster: Dihydroorotase; n=2; Thermoplasmatales|... 40 0.078 UniRef50_Q2JMN8 Cluster: Dihydroorotase, putative; n=2; Synechoc... 39 0.14 UniRef50_Q24PA5 Cluster: Putative uncharacterized protein; n=1; ... 39 0.14 UniRef50_Q6BV31 Cluster: Similar to CA5801|CaDAL1 Candida albica... 39 0.14 UniRef50_P40757 Cluster: Allantoinase, mitochondrial precursor; ... 39 0.14 UniRef50_Q84FR6 Cluster: D-hydantoinase; n=1; Arthrobacter cryst... 39 0.18 UniRef50_A6CCA9 Cluster: Dihydroorotase, multifunctional complex... 39 0.18 UniRef50_Q972W9 Cluster: 413aa long hypothetical D-hydantoinase;... 39 0.18 UniRef50_P32375 Cluster: Allantoinase; n=3; Saccharomycetaceae|R... 39 0.18 UniRef50_Q5NPE4 Cluster: Dihydroorotase; n=8; Sphingomonadales|R... 38 0.24 UniRef50_Q31EK1 Cluster: Aspartate carbamoyltransferase, non-cat... 38 0.24 UniRef50_A1A2Z8 Cluster: Putative allantoinase; n=3; Bifidobacte... 38 0.24 UniRef50_Q2GR02 Cluster: Putative uncharacterized protein; n=4; ... 38 0.24 UniRef50_Q31R01 Cluster: Dihydroorotase and related cyclic amido... 38 0.31 UniRef50_A5KJ64 Cluster: Putative uncharacterized protein; n=1; ... 38 0.31 UniRef50_Q259B7 Cluster: H0901F07.3 protein; n=12; Magnoliophyta... 38 0.31 UniRef50_Q5PR45 Cluster: Zgc:103559; n=8; Eumetazoa|Rep: Zgc:103... 38 0.41 UniRef50_Q8EW20 Cluster: Dihydroorotase; n=1; Mycoplasma penetra... 38 0.41 UniRef50_A3DM45 Cluster: Amidohydrolase; n=1; Staphylothermus ma... 38 0.41 UniRef50_Q8G657 Cluster: Dihydroorotase; n=4; Bifidobacterium|Re... 37 0.55 UniRef50_A6NQ76 Cluster: Putative uncharacterized protein; n=1; ... 37 0.55 UniRef50_A6G7W0 Cluster: Dihydroorotase and related cyclic amido... 37 0.55 UniRef50_Q9YFI5 Cluster: Dihydroorotase; n=1; Aeropyrum pernix|R... 37 0.55 UniRef50_Q30S48 Cluster: Amidohydrolase; n=1; Thiomicrospira den... 37 0.72 UniRef50_Q08M50 Cluster: Allantoinase; n=1; Stigmatella aurantia... 37 0.72 UniRef50_A5ZUT5 Cluster: Putative uncharacterized protein; n=1; ... 37 0.72 UniRef50_Q1ERB5 Cluster: L-hydantoinase HyuH; n=1; uncultured cr... 37 0.72 UniRef50_Q2KUT6 Cluster: Dihydroorotase precursor; n=1; Bordetel... 36 0.96 UniRef50_A6LUW0 Cluster: Dihydropyrimidinase; n=1; Clostridium b... 36 0.96 UniRef50_Q97C35 Cluster: Dihydroorotase; n=2; Thermoplasma|Rep: ... 36 0.96 UniRef50_Q4T977 Cluster: Chromosome undetermined SCAF7631, whole... 36 1.3 UniRef50_Q7WMP7 Cluster: Dihydroorotase-like protein; n=3; Borde... 36 1.3 UniRef50_Q47RB7 Cluster: Allantoinase; n=1; Thermobifida fusca Y... 36 1.3 UniRef50_A4CLI6 Cluster: Dihydroorotase, multifunctional complex... 36 1.3 UniRef50_A0K2C1 Cluster: Dihydropyrimidinase; n=1; Arthrobacter ... 36 1.3 UniRef50_Q972L4 Cluster: 464aa long hypothetical D-hydantoinase;... 36 1.3 UniRef50_Q7UNR2 Cluster: Putative dihydroorotase; n=1; Pirellula... 36 1.3 UniRef50_Q59699 Cluster: D-hydantoinase; n=11; Proteobacteria|Re... 36 1.3 UniRef50_Q1AZI1 Cluster: D-hydantoinase; n=1; Rubrobacter xylano... 36 1.7 UniRef50_Q0VTM6 Cluster: Dihydroorotase, multifunctional complex... 36 1.7 UniRef50_A6VSQ0 Cluster: Dihydroorotase, multifunctional complex... 36 1.7 UniRef50_A3HYA6 Cluster: Dihydroorotase and related cyclic amido... 36 1.7 UniRef50_A4R534 Cluster: Putative uncharacterized protein; n=1; ... 36 1.7 UniRef50_Q972X8 Cluster: 433aa long hypothetical D-hydantoinase;... 36 1.7 UniRef50_Q45515 Cluster: D-hydantoinase; n=14; Bacteria|Rep: D-h... 36 1.7 UniRef50_UPI00015B49FE Cluster: PREDICTED: similar to alpha-gluc... 35 2.2 UniRef50_A6WFZ1 Cluster: Dihydropyrimidinase; n=1; Kineococcus r... 35 2.2 UniRef50_A5GXS3 Cluster: Faciata 1-like protein; n=6; Poaceae|Re... 35 2.2 UniRef50_Q2LWS0 Cluster: DNA polymerase III, delta subunit; n=1;... 35 2.9 UniRef50_A3PPE1 Cluster: Dihydropyrimidinase; n=3; Rhodobacter s... 35 2.9 UniRef50_Q7JZT9 Cluster: RE13129p; n=5; Diptera|Rep: RE13129p - ... 35 2.9 UniRef50_Q11EY4 Cluster: Dihydropyrimidinase; n=25; Proteobacter... 34 3.9 UniRef50_Q0BZU5 Cluster: Putative dihydroorotase; n=1; Hyphomona... 34 3.9 UniRef50_A3UJX0 Cluster: Aspartate transcarbamoylase, pyrC' subu... 34 3.9 UniRef50_UPI0001554813 Cluster: PREDICTED: hypothetical protein;... 34 5.1 UniRef50_Q12EE5 Cluster: Allantoinase; n=57; Betaproteobacteria|... 34 5.1 UniRef50_A3ZYR8 Cluster: Dihydroorotase; n=1; Blastopirellula ma... 34 5.1 UniRef50_Q18IV3 Cluster: Dihydroorotase; n=1; Haloquadratum wals... 34 5.1 UniRef50_Q8YF78 Cluster: D-HYDANTOINASE; n=41; Proteobacteria|Re... 33 6.8 UniRef50_P72934 Cluster: Probable dihydroorotase-like protein; n... 33 6.8 >UniRef50_Q1RKZ5 Cluster: IP15551p; n=1; Drosophila melanogaster|Rep: IP15551p - Drosophila melanogaster (Fruit fly) Length = 746 Score = 145 bits (352), Expect = 1e-33 Identities = 64/107 (59%), Positives = 79/107 (73%) Frame = -2 Query: 557 SASCSSKDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRP 378 S +C K L F L DMT WQ+H WPK+ P+ HAER+ TAAVI++A LLDR Sbjct: 331 SHACGLKMYLNDTFGTLKLSDMTSWQRHLSHWPKRSPIVCHAERQSTAAVIMLAHLLDRS 390 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKG 237 VHICHVARKEEI +I++AKE+GVKVTCEVCPHHLFL++ D+ +L G Sbjct: 391 VHICHVARKEEIQLIRSAKEKGVKVTCEVCPHHLFLSTKDVERLGHG 437 Score = 122 bits (294), Expect = 1e-26 Identities = 63/106 (59%), Positives = 71/106 (66%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 IVKLPGFIDVHVH+REPGA K F +T++CAMPNTNPSIVDR F Sbjct: 242 IVKLPGFIDVHVHLREPGATHKEDFASGTAAA-LAGGVTLVCAMPNTNPSIVDRETFTQF 300 Query: 646 STLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFTT 509 LA+ ARCDYALYVGAS N+ + ELA A LKMYLN+TF T Sbjct: 301 QELAKAGARCDYALYVGASDDNWAQVNELASHACGLKMYLNDTFGT 346 Score = 37.9 bits (84), Expect = 0.31 Identities = 14/25 (56%), Positives = 19/25 (76%) Frame = -1 Query: 252 KIGKGRAKVCPVLCSPEDQAELWRN 178 ++G G ++V P+LCSPEDQ LW N Sbjct: 433 RLGHGMSEVRPLLCSPEDQEALWEN 457 >UniRef50_P05990 Cluster: CAD protein (Protein rudimentary) [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]; n=206; cellular organisms|Rep: CAD protein (Protein rudimentary) [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] - Drosophila melanogaster (Fruit fly) Length = 2224 Score = 145 bits (352), Expect = 1e-33 Identities = 64/107 (59%), Positives = 79/107 (73%) Frame = -2 Query: 557 SASCSSKDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRP 378 S +C K L F L DMT WQ+H WPK+ P+ HAER+ TAAVI++A LLDR Sbjct: 1565 SHACGLKMYLNDTFGTLKLSDMTSWQRHLSHWPKRSPIVCHAERQSTAAVIMLAHLLDRS 1624 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKG 237 VHICHVARKEEI +I++AKE+GVKVTCEVCPHHLFL++ D+ +L G Sbjct: 1625 VHICHVARKEEIQLIRSAKEKGVKVTCEVCPHHLFLSTKDVERLGHG 1671 Score = 127 bits (306), Expect = 4e-28 Identities = 54/77 (70%), Positives = 65/77 (84%) Frame = -1 Query: 252 KIGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETIL 73 ++G G ++V P+LCSPEDQ LW NI IDVFATDHAPHT+ EK SE PPPG+PG+ETIL Sbjct: 1667 RLGHGMSEVRPLLCSPEDQEALWENIDYIDVFATDHAPHTLAEKRSERPPPGFPGVETIL 1726 Query: 72 PLLLNAVHQGRLTIEDL 22 PLLL AVH+GRLT+ED+ Sbjct: 1727 PLLLQAVHEGRLTMEDI 1743 Score = 122 bits (294), Expect = 1e-26 Identities = 63/106 (59%), Positives = 71/106 (66%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 IVKLPGFIDVHVH+REPGA K F +T++CAMPNTNPSIVDR F Sbjct: 1476 IVKLPGFIDVHVHLREPGATHKEDFASGTAAA-LAGGVTLVCAMPNTNPSIVDRETFTQF 1534 Query: 646 STLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFTT 509 LA+ ARCDYALYVGAS N+ + ELA A LKMYLN+TF T Sbjct: 1535 QELAKAGARCDYALYVGASDDNWAQVNELASHACGLKMYLNDTFGT 1580 >UniRef50_A7T4N0 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1362 Score = 129 bits (312), Expect = 7e-29 Identities = 55/98 (56%), Positives = 71/98 (72%) Frame = -2 Query: 539 KDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHV 360 K L F L+D+TIW KH ++WP MP+ HAE TAA++L+A L DRPVHI HV Sbjct: 992 KMYLNETFTTLRLDDLTIWMKHLENWPLHMPIVCHAEGRTTAAILLLAELADRPVHIAHV 1051 Query: 359 ARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246 ARKEEI++I+AAKERG+ VTCEV PHHLF+ +D ++ Sbjct: 1052 ARKEEIMVIRAAKERGLAVTCEVAPHHLFMTKDDAARI 1089 Score = 119 bits (286), Expect = 1e-25 Identities = 54/81 (66%), Positives = 64/81 (79%) Frame = -1 Query: 252 KIGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETIL 73 +IG+ +V P L + EDQ LW N+ ID FATDHAPHT+EEKNS N PPG+PGLET+L Sbjct: 1088 RIGESWIRVKPPLVTAEDQMALWDNMEYIDCFATDHAPHTIEEKNSTNSPPGFPGLETML 1147 Query: 72 PLLLNAVHQGRLTIEDLLCRI 10 PLLL AVHQGRLTIEDL+ R+ Sbjct: 1148 PLLLTAVHQGRLTIEDLVKRL 1168 Score = 117 bits (281), Expect = 4e-25 Identities = 59/106 (55%), Positives = 71/106 (66%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 IV+LPG IDVHVH+REPGA K F +TM+ AMPNTNP +VD +F+ A Sbjct: 897 IVRLPGLIDVHVHLREPGATHKEDFASGTAAA-LAGGITMVLAMPNTNPPLVDEESFNLA 955 Query: 646 STLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFTT 509 L ARCDYALY+GA TNY + ++A +AA LKMYLNETFTT Sbjct: 956 KKLGTAGARCDYALYLGAGPTNYTMLKDIAHRAAGLKMYLNETFTT 1001 >UniRef50_P27708 Cluster: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]; n=277; cellular organisms|Rep: CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)] - Homo sapiens (Human) Length = 2225 Score = 123 bits (297), Expect = 5e-27 Identities = 56/109 (51%), Positives = 76/109 (69%) Frame = -2 Query: 560 GSASCSSKDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDR 381 GSA+ K L F L+ + W +HF++WP +P+ HAE++ AAV+++A L R Sbjct: 1550 GSAA-GLKLYLNETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQR 1608 Query: 380 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKGE 234 VHICHVARKEEIL+IKAAK RG+ VTCEV PHHLFL+ +D+ +L G+ Sbjct: 1609 SVHICHVARKEEILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGK 1657 Score = 110 bits (264), Expect = 5e-23 Identities = 47/83 (56%), Positives = 64/83 (77%) Frame = -1 Query: 252 KIGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETIL 73 ++G G+ +V P L S +D LW N+++ID FA+DHAPHT+EEK PPPG+PGLET+L Sbjct: 1652 RLGPGKGEVRPELGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGSRPPPGFPGLETML 1711 Query: 72 PLLLNAVHQGRLTIEDLLCRIRH 4 PLLL AV +GRL+++DLL R+ H Sbjct: 1712 PLLLTAVSEGRLSLDDLLQRLHH 1734 Score = 105 bits (253), Expect = 1e-21 Identities = 54/105 (51%), Positives = 67/105 (63%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 +V+LPG IDVHVH+REPG K F +TM+CAMPNT P I+D A A Sbjct: 1461 LVRLPGLIDVHVHLREPGGTHKEDFASGTAAA-LAGGITMVCAMPNTRPPIIDAPALALA 1519 Query: 646 STLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFT 512 LA ARCD+AL++GASS N T+ +A AA LK+YLNETF+ Sbjct: 1520 QKLAEAGARCDFALFLGASSENAGTLGTVAGSAAGLKLYLNETFS 1564 >UniRef50_Q5RHG8 Cluster: Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; n=23; Coelomata|Rep: Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 2154 Score = 120 bits (290), Expect = 3e-26 Identities = 49/84 (58%), Positives = 68/84 (80%) Frame = -2 Query: 491 TIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG 312 T+ QKHF+ WPK +P+ HAE++ AA++L+A L RPVHICHVA+KEEILII+AAK++G Sbjct: 1523 TMAQKHFEKWPKHLPIVAHAEKQTVAAILLVAQLYQRPVHICHVAKKEEILIIRAAKQKG 1582 Query: 311 VKVTCEVCPHHLFLNSNDITKLEK 240 ++VTCEV PHHLFL +++ + K Sbjct: 1583 IQVTCEVAPHHLFLCEDNVPVIGK 1606 Score = 114 bits (274), Expect = 3e-24 Identities = 50/80 (62%), Positives = 63/80 (78%) Frame = -1 Query: 249 IGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILP 70 IGK +A+V P+L + ED LW N+ IID FATDHAPH+ EEK SE PPPGYPGLET+LP Sbjct: 1604 IGKDKAQVRPMLGTREDMEALWENLDIIDCFATDHAPHSAEEKISEKPPPGYPGLETMLP 1663 Query: 69 LLLNAVHQGRLTIEDLLCRI 10 LL AV +GRLT++D++ R+ Sbjct: 1664 LLFTAVSEGRLTVDDIIKRL 1683 Score = 62.1 bits (144), Expect = 2e-08 Identities = 30/60 (50%), Positives = 39/60 (65%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 +++LPG IDVHVH+REPGA K F +TM+CAMPNTNP+I+D +F A Sbjct: 1467 LIRLPGLIDVHVHLREPGATHKEDF-SSGTAAALAGGITMVCAMPNTNPAIIDPNSFTMA 1525 >UniRef50_Q4SZL4 Cluster: Chromosome 14 SCAF11586, whole genome shotgun sequence; n=2; cellular organisms|Rep: Chromosome 14 SCAF11586, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2178 Score = 120 bits (288), Expect = 6e-26 Identities = 53/81 (65%), Positives = 66/81 (81%) Frame = -1 Query: 252 KIGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETIL 73 +IG GRA+V P+L S ED LW N+ IID FATDHAPH++EEKNS +PPPGYPGLET+L Sbjct: 1573 EIGSGRAQVRPMLGSREDMEALWENLDIIDCFATDHAPHSLEEKNSGSPPPGYPGLETML 1632 Query: 72 PLLLNAVHQGRLTIEDLLCRI 10 PLLL AV GRLT++D++ R+ Sbjct: 1633 PLLLTAVSDGRLTLDDIIKRL 1653 Score = 101 bits (241), Expect = 3e-20 Identities = 50/126 (39%), Positives = 74/126 (58%), Gaps = 25/126 (19%) Frame = -2 Query: 539 KDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHV 360 K L F ++++++W +HF+ WP+ MP+ HAE++ AA++++A L RPVHICHV Sbjct: 1452 KMYLNDTFSTLKMDNVSLWMEHFEMWPRHMPIVAHAEKQTVAAILMVAQLYQRPVHICHV 1511 Query: 359 ARKEE-------------------------ILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 ARKEE I II+AAK +G++VTCEV PHHLFL +D+ Sbjct: 1512 ARKEEVNPHLLLLYFTSLVTNISDVLFSSQISIIRAAKLKGIQVTCEVAPHHLFLCEDDV 1571 Query: 254 TKLEKG 237 ++ G Sbjct: 1572 VEIGSG 1577 Score = 97.5 bits (232), Expect = 4e-19 Identities = 55/118 (46%), Positives = 70/118 (59%), Gaps = 12/118 (10%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 +V+LPG IDVHVH+REPGA K F +TM+CAMPNT+PS+ D T Sbjct: 1345 LVRLPGLIDVHVHLREPGATHKEDF-SSGTAAALAGGVTMVCAMPNTSPSVTDPTTLALV 1403 Query: 646 ST------------LARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFTT 509 LA+ +RCDYALY+GA+S N + +A QA ALKMYLN+TF+T Sbjct: 1404 QKEANREAACLGFQLAKAGSRCDYALYLGAASDNAAILPSIAGQAVALKMYLNDTFST 1461 >UniRef50_Q8U4A0 Cluster: Dihydroorotase; n=5; Thermococcaceae|Rep: Dihydroorotase - Pyrococcus furiosus Length = 414 Score = 77.4 bits (182), Expect = 4e-13 Identities = 37/71 (52%), Positives = 52/71 (73%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAV 52 KV P L S ED+ LW+NI + V A+DHAPHT+E+K E G PGLET +PLLL+AV Sbjct: 245 KVYPPLRSEEDRIALWKNIDKVPVIASDHAPHTLEDK--EAGAAGLPGLETEVPLLLDAV 302 Query: 51 HQGRLTIEDLL 19 ++G +T++D++ Sbjct: 303 NKGLITLQDIV 313 Score = 40.7 bits (91), Expect = 0.045 Identities = 23/74 (31%), Positives = 37/74 (50%) Frame = -2 Query: 470 QSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEV 291 Q +P++ P+ AE VI +P HICH++ + + ++ R ++ EV Sbjct: 172 QKYPERPPI---AEIRAIERVIEAVKTHKKPAHICHISTAKGLKLL--LDSRLEMLSFEV 226 Query: 290 CPHHLFLNSNDITK 249 PHHLFL +D K Sbjct: 227 TPHHLFLTRSDYDK 240 Score = 39.1 bits (87), Expect = 0.14 Identities = 25/73 (34%), Positives = 36/73 (49%) Frame = -3 Query: 823 VKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYAS 644 V LPG IDVHVH+R+ + K + + +T++ MPNT P I+D Sbjct: 48 VILPGLIDVHVHLRDFEESYKESI-ESGTKAAVHGGITVVFDMPNTKPPIMDEKTLKLRE 106 Query: 643 TLARVSARCDYAL 605 L + + DYAL Sbjct: 107 HLFKRKSYADYAL 119 >UniRef50_A6RFE1 Cluster: Bifunctional pyrimidine biosynthesis protein pyrABCN; n=4; Fungi/Metazoa group|Rep: Bifunctional pyrimidine biosynthesis protein pyrABCN - Ajellomyces capsulatus NAm1 Length = 2404 Score = 75.4 bits (177), Expect = 2e-12 Identities = 32/73 (43%), Positives = 51/73 (69%) Frame = -2 Query: 476 HFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTC 297 HF SWP P+ T A+ A+++L+ASL +R +H+ V KE+I +I +KE+G+KVTC Sbjct: 1796 HFASWPTNKPIITDAKATDLASILLLASLHNRNIHVMSVTSKEDIGLIALSKEKGLKVTC 1855 Query: 296 EVCPHHLFLNSND 258 +V + LFL+++D Sbjct: 1856 DVAIYSLFLSTDD 1868 Score = 52.8 bits (121), Expect = 1e-05 Identities = 28/72 (38%), Positives = 40/72 (55%) Frame = -1 Query: 225 CPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQ 46 C L S +DQ LW ++ ID+F+ P+ V KN+ P G++ LPLL AV Sbjct: 1872 CACLPSKKDQEALWEHLDSIDIFSIGSLPYQVAGKNAS---PAV-GIQDALPLLFTAVSD 1927 Query: 45 GRLTIEDLLCRI 10 RLT+ED+ R+ Sbjct: 1928 KRLTVEDITSRL 1939 >UniRef50_A2SQD3 Cluster: Dihydroorotase, multifunctional complex type; n=1; Methanocorpusculum labreanum Z|Rep: Dihydroorotase, multifunctional complex type - Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) Length = 421 Score = 70.1 bits (164), Expect = 6e-11 Identities = 34/74 (45%), Positives = 52/74 (70%), Gaps = 3/74 (4%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKN---SENPPPGYPGLETILPLLL 61 K+ P L S +++ L +N + I V A+DHAPHT++EK+ S + P G PG+ET+LPLL+ Sbjct: 254 KMNPPLRSKKERLHLIQNFAKIPVIASDHAPHTIQEKSQPFSASAPSGVPGVETMLPLLM 313 Query: 60 NAVHQGRLTIEDLL 19 NAV Q +T+ D++ Sbjct: 314 NAVTQRTITLNDVI 327 >UniRef50_A1RZC7 Cluster: Dihydroorotase, multifunctional complex type; n=1; Thermofilum pendens Hrk 5|Rep: Dihydroorotase, multifunctional complex type - Thermofilum pendens (strain Hrk 5) Length = 431 Score = 66.9 bits (156), Expect = 6e-10 Identities = 34/70 (48%), Positives = 46/70 (65%), Gaps = 2/70 (2%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLL 61 AKV P L D++ ++ ++ + D TDHAPH+ EEK SE+PPPG+PGLE L LLL Sbjct: 265 AKVNPPLRGEADRSAVYSALARGLPDALVTDHAPHSPEEKASEDPPPGFPGLELALHLLL 324 Query: 60 NAVHQGRLTI 31 + V GRL + Sbjct: 325 SEVLAGRLPL 334 Score = 39.9 bits (89), Expect = 0.078 Identities = 33/106 (31%), Positives = 44/106 (41%), Gaps = 4/106 (3%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644 LPG +D+HVH+REPG K D V +T + MPN P T A Sbjct: 56 LPGMVDIHVHMREPGQEYKE---DWRTGSRAAVKGGVTFVADMPNNKPPA--NTCERLAE 110 Query: 643 TLARVSAR--CDYALYVGASSTNYDTICELAPQAAALKMYLNETFT 512 L R + D+A Y G S N + + K+Y E F+ Sbjct: 111 KLRRAGEKSLVDFAFYAGFSE-NPEELLRCPELFVGGKLYPEELFS 155 Score = 33.9 bits (74), Expect = 5.1 Identities = 14/39 (35%), Positives = 22/39 (56%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261 VH+ HV+ + + +AK G+K T +V PHH L + Sbjct: 217 VHVTHVSTGAAVTELLSAKLSGLKATFDVTPHHALLTDS 255 >UniRef50_Q8YUN6 Cluster: Dihydroorotase; n=4; Bacteria|Rep: Dihydroorotase - Anabaena sp. (strain PCC 7120) Length = 439 Score = 65.7 bits (153), Expect = 1e-09 Identities = 34/72 (47%), Positives = 45/72 (62%), Gaps = 4/72 (5%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67 A++ P L SP D LW+ + +ID ATDHAPHT+EEK N P G PG+ET L + Sbjct: 275 AQMNPPLRSPHDNEVLWQALRDGVIDFIATDHAPHTLEEKAQPYPNSPSGMPGVETSLAV 334 Query: 66 LLNAVHQGRLTI 31 +L A +G+ TI Sbjct: 335 MLTAAMEGKCTI 346 Score = 40.7 bits (91), Expect = 0.045 Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 4/101 (3%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644 LPG ID VH REPG K DL +T MPNT P + A D Sbjct: 57 LPGVIDPQVHFREPGLEHKE---DLFTASCACAKGGVTSFLEMPNTRPLTTTQQALD--D 111 Query: 643 TLARVSARC--DYALYVGASSTNYDTICELAPQAAALKMYL 527 L R +++C +Y ++GA+ N + P +K+++ Sbjct: 112 KLQRAASKCLVNYGFFIGATGDNTPELLAAHP-TPGIKIFM 151 >UniRef50_Q0W790 Cluster: Dihydroorotase; n=1; uncultured methanogenic archaeon RC-I|Rep: Dihydroorotase - Uncultured methanogenic archaeon RC-I Length = 451 Score = 64.9 bits (151), Expect = 2e-09 Identities = 34/76 (44%), Positives = 48/76 (63%), Gaps = 4/76 (5%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67 AK+ P + D+ LW+ N I+V A+DHAPHT++EKN P G PG+ET+LPL Sbjct: 269 AKMNPPIRHDSDRNALWKAVNDGSIEVLASDHAPHTLDEKNLPVREAPSGVPGVETMLPL 328 Query: 66 LLNAVHQGRLTIEDLL 19 +L AV RL ++ L+ Sbjct: 329 MLKAVADKRLPLQRLI 344 Score = 35.5 bits (78), Expect = 1.7 Identities = 25/79 (31%), Positives = 38/79 (48%) Frame = -3 Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFD 653 G +V +PG ID HVH R+ K + + V T++ MPN++P D AF Sbjct: 46 GRLV-MPGVIDSHVHFRDMRQEEKEDWLSGSKAALYGGVTTVV-DMPNSDPPTFDAEAFK 103 Query: 652 YASTLARVSARCDYALYVG 596 T+A + D++L G Sbjct: 104 VKQTVAANRSMVDFSLNAG 122 >UniRef50_UPI0000DAE5C6 Cluster: hypothetical protein Rgryl_01000723; n=1; Rickettsiella grylli|Rep: hypothetical protein Rgryl_01000723 - Rickettsiella grylli Length = 409 Score = 64.5 bits (150), Expect = 3e-09 Identities = 37/78 (47%), Positives = 46/78 (58%), Gaps = 4/78 (5%) Frame = -1 Query: 240 GRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETIL 73 G+A + P L S E Q L+ I IID +DHAPHT EEK P G PG+ET L Sbjct: 262 GKAIMNPPLRSSEHQRALFSAIKLGIIDTIGSDHAPHTQEEKAKPYGLCPSGVPGIETAL 321 Query: 72 PLLLNAVHQGRLTIEDLL 19 PLLL A HQ +T+ D++ Sbjct: 322 PLLLEAYHQDLITLTDIV 339 Score = 50.4 bits (115), Expect = 6e-05 Identities = 28/71 (39%), Positives = 42/71 (59%), Gaps = 7/71 (9%) Frame = -2 Query: 437 HAE-REKTAAVIL------MASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 279 H+E R+++AA+I + L ++I HV+ ++EI +I AKE G+ + E PHH Sbjct: 190 HSEIRDESAAIIAVKKAIQLVRLYKTRLYILHVSTRQEIDLIAQAKEEGLPIFAETTPHH 249 Query: 278 LFLNSNDITKL 246 LFLN ND L Sbjct: 250 LFLNVNDYPDL 260 Score = 33.1 bits (72), Expect = 8.9 Identities = 25/106 (23%), Positives = 43/106 (40%), Gaps = 5/106 (4%) Frame = -3 Query: 829 NIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDY 650 +++ PG ID HVH R PG K + + T + MPNT P + + A Sbjct: 31 HLLVFPGLIDPHVHFRTPGLEYKENW-TTAAKASIKGGYTTVFDMPNTLPPTITKEALIE 89 Query: 649 AST-----LARVSARCDYALYVGASSTNYDTICELAPQAAALKMYL 527 L + Y L+ GA + I ++ + +K+++ Sbjct: 90 KKALIDKQLKAIGIPLRYHLFFGADKHHLHEIKKVNDKVIGIKVFM 135 >UniRef50_Q4JN07 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihydroorotase - uncultured bacterium BAC13K9BAC Length = 444 Score = 64.1 bits (149), Expect = 4e-09 Identities = 29/72 (40%), Positives = 48/72 (66%), Gaps = 4/72 (5%) Frame = -1 Query: 222 PVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPLLLNA 55 P + + Q LW N ++D+ A+DHAPHT++EK+ P P G PG++T++P++LN Sbjct: 281 PPIREKKHQDALWDALNSGVVDIVASDHAPHTLDEKSQIYPKSPSGTPGVQTLVPIMLNH 340 Query: 54 VHQGRLTIEDLL 19 V+ G+LT+ L+ Sbjct: 341 VNNGKLTLAKLV 352 Score = 44.0 bits (99), Expect = 0.005 Identities = 31/92 (33%), Positives = 41/92 (44%), Gaps = 3/92 (3%) Frame = -3 Query: 829 NIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV---LTMICAMPNTNPSIVDRTA 659 N+ LPG ID VH REPG ++G+ + L V +T I MPNTNP + Sbjct: 51 NLTVLPGVIDSQVHFREPG--LEGK--ENLESGMLAAVSGGVTSIFEMPNTNPLTITPET 106 Query: 658 FDYASTLARVSARCDYALYVGASSTNYDTICE 563 A A DYA Y+G + + E Sbjct: 107 IQDKLNRASKGAWTDYAFYLGGTMRTSSNLSE 138 >UniRef50_Q58885 Cluster: Dihydroorotase; n=6; Methanococcales|Rep: Dihydroorotase - Methanococcus jannaschii Length = 423 Score = 63.3 bits (147), Expect = 7e-09 Identities = 33/79 (41%), Positives = 49/79 (62%), Gaps = 4/79 (5%) Frame = -1 Query: 243 KGRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETI 76 KG K P L +D L + I +D+ A+DHAPH +E+K N +N P G PG+ETI Sbjct: 269 KGFGKFNPPLREKDDNIALIKGIVNKDVDIIASDHAPHLLEDKLKNVKNCPSGIPGIETI 328 Query: 75 LPLLLNAVHQGRLTIEDLL 19 +PL LN V++G +++ D + Sbjct: 329 VPLTLNLVNKGLISLFDAI 347 Score = 53.6 bits (123), Expect = 6e-06 Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 2/107 (1%) Frame = -2 Query: 539 KDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHV 360 KDV+ N + L W H + +K V E K +I S VH CH+ Sbjct: 172 KDVINENLKKYQLNS---WIDHCKIRDEKSEVEAVKEVIKNLKIIDRQSNKKPHVHFCHI 228 Query: 359 ARKEEILIIKAAKE--RGVKVTCEVCPHHLFLNSNDITKLEKGEQKY 225 + KE + +IK ++ + +K+T EV PHH++LN D+ + KG K+ Sbjct: 229 STKEALYLIKKVRQELKNIKITVEVTPHHIYLN-KDMAEELKGFGKF 274 >UniRef50_Q7NF57 Cluster: Dihydroorotase; n=12; Cyanobacteria|Rep: Dihydroorotase - Gloeobacter violaceus Length = 443 Score = 62.9 bits (146), Expect = 1e-08 Identities = 32/77 (41%), Positives = 46/77 (59%), Gaps = 4/77 (5%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 70 RAK P L S D+ +W + +ID ATDHAPH + EK+ + P G PG+ET LP Sbjct: 274 RAKQNPPLRSEADREAMWAGLRSGLIDFVATDHAPHLLSEKDRDYAEAPAGMPGVETSLP 333 Query: 69 LLLNAVHQGRLTIEDLL 19 L+L A+ +G + E ++ Sbjct: 334 LMLTALARGEVNFEQIV 350 Score = 50.4 bits (115), Expect = 6e-05 Identities = 34/107 (31%), Positives = 52/107 (48%), Gaps = 5/107 (4%) Frame = -3 Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV---LTMICAMPNTNPSIVDRT 662 G V LPG ID VH REPG K + L W +T MPNT+P T Sbjct: 51 GGRVLLPGVIDPQVHFREPGKEYK----EDLQTGSWACARGGVTSFLEMPNTSPPTT--T 104 Query: 661 AFDYASTLARVSARC--DYALYVGASSTNYDTICELAPQAAALKMYL 527 LAR +++C +Y +VGA++ N + + + A + +K+++ Sbjct: 105 VERLEDKLARAASKCVVNYGFFVGATADNIEQLQQAAGLSCGVKIFM 151 Score = 36.7 bits (81), Expect = 0.72 Identities = 19/55 (34%), Positives = 33/55 (60%) Frame = -2 Query: 428 REKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264 R TA + ++ R +HI H++ EE+ +++A ++ VT EV P HLFL++ Sbjct: 213 RLATAQALELSRRYRRRLHILHLSAAEELELLRA--DKPAWVTAEVIPQHLFLST 265 >UniRef50_Q8ZZC7 Cluster: Dihydroorotase; n=4; Pyrobaculum|Rep: Dihydroorotase - Pyrobaculum aerophilum Length = 383 Score = 62.5 bits (145), Expect = 1e-08 Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 2/81 (2%) Frame = -1 Query: 240 GRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPL 67 G V P L +PE + L + ++D++ATDHAPHT+EEK S PPPG L+ L L Sbjct: 232 GLCHVNPRLRTPEMRKRLLAAFASGLVDIYATDHAPHTLEEKRSGAPPPGICSLDVALSL 291 Query: 66 LLNAVHQGRLTIEDLLCRIRH 4 LL +G +T+ D++ H Sbjct: 292 LLTLWKRGVVTLSDVVRLYSH 312 >UniRef50_O28034 Cluster: Dihydroorotase; n=1; Archaeoglobus fulgidus|Rep: Dihydroorotase - Archaeoglobus fulgidus Length = 403 Score = 61.3 bits (142), Expect = 3e-08 Identities = 32/73 (43%), Positives = 46/73 (63%) Frame = -1 Query: 228 VCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVH 49 V P L ED L+RN IDV A+DHAPHT+E+K E G+PG+ET+ PL +N Sbjct: 251 VNPPLREREDVEWLFRNFHRIDVLASDHAPHTLEDK--EAGASGFPGVETMYPLFVNLAS 308 Query: 48 QGRLTIEDLLCRI 10 +G ++ + L+ +I Sbjct: 309 KGYISFKTLVEKI 321 Score = 35.9 bits (79), Expect = 1.3 Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 1/86 (1%) Frame = -3 Query: 823 VKLPGFIDVHVHVREPGANIKGRF*D-LLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 V LP IDVHVH+R+ K L H + L + PNT P + D + Sbjct: 39 VILPAGIDVHVHLRDFAEKRKETIETGTLSALHGGICL--VVDQPNTKPPVDDAETYFRR 96 Query: 646 STLARVSARCDYALYVGASSTNYDTI 569 A S DYAL + +++N+ I Sbjct: 97 MGKAEKSVYVDYALNLALTNSNHGKI 122 >UniRef50_A0B872 Cluster: Dihydroorotase, multifunctional complex type; n=1; Methanosaeta thermophila PT|Rep: Dihydroorotase, multifunctional complex type - Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrixthermophila (strain DSM 6194 / PT)) Length = 432 Score = 60.9 bits (141), Expect = 4e-08 Identities = 33/72 (45%), Positives = 43/72 (59%), Gaps = 4/72 (5%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64 K P L + D LW + IDV A+DHAPH EEK + + PPG PG+ET+LPL+ Sbjct: 260 KTNPPLRNTADCDALWDGLRRRDIDVIASDHAPHLPEEKRDDIWHAPPGVPGVETMLPLM 319 Query: 63 LNAVHQGRLTIE 28 L AV +T+E Sbjct: 320 LYAVKSNMITLE 331 Score = 48.4 bits (110), Expect = 2e-04 Identities = 19/44 (43%), Positives = 30/44 (68%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246 +HICH++ + + ++K + R KV+CEV PHHLFL+ D +L Sbjct: 214 IHICHISTADGLELVKRRRNR--KVSCEVAPHHLFLSRRDYRRL 255 Score = 37.5 bits (83), Expect = 0.41 Identities = 22/77 (28%), Positives = 39/77 (50%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 ++ +PG ID+HVH R+PG K + + +T + PNT+P ++D ++ Sbjct: 47 MIIIPGVIDMHVHFRDPGYTHKEDW-ESGSISAAAGGVTTVVDQPNTDPPVMDAESYKEK 105 Query: 646 STLARVSARCDYALYVG 596 LA+ + D+ L G Sbjct: 106 LNLAKRRSIVDFCLNGG 122 >UniRef50_Q9HMH9 Cluster: Dihydroorotase; n=6; Halobacteriaceae|Rep: Dihydroorotase - Halobacterium salinarium (Halobacterium halobium) Length = 422 Score = 60.1 bits (139), Expect = 7e-08 Identities = 29/49 (59%), Positives = 35/49 (71%), Gaps = 2/49 (4%) Frame = -1 Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIE 28 IDV ATDHAPHT EK ++ + P G PG+ET LPLLL A H+G L+ E Sbjct: 285 IDVVATDHAPHTRAEKAADIWDAPSGVPGVETALPLLLGAAHRGELSYE 333 Score = 34.3 bits (75), Expect = 3.9 Identities = 18/44 (40%), Positives = 24/44 (54%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246 +HI H + E + AA G TCE PHHLFL+ +D+ L Sbjct: 219 IHIAHTSTPEGV---DAAAAGGA--TCEATPHHLFLSRDDLDDL 257 Score = 33.9 bits (74), Expect = 5.1 Identities = 24/76 (31%), Positives = 33/76 (43%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638 LPG ID HVH R+PG K + V T++ PNT P V A D + Sbjct: 46 LPGMIDAHVHFRQPGFEHKETWASGSRSAAAGGVTTVV-DQPNTAPPTVTGDAVDEKAAH 104 Query: 637 ARVSARCDYALYVGAS 590 A + D+ + G + Sbjct: 105 AAADSVVDWGVNGGVT 120 >UniRef50_Q2FLR3 Cluster: Dihydroorotase; n=3; Methanomicrobiales|Rep: Dihydroorotase - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 431 Score = 59.3 bits (137), Expect = 1e-07 Identities = 30/77 (38%), Positives = 48/77 (62%), Gaps = 2/77 (2%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64 + KV P L S + + EL+ ID+ +DHAPHT EK E + P G PG+ET++PLL Sbjct: 260 QGKVNPPLRSEKVRRELFSCWDQIDIIGSDHAPHTRAEKGKEFEHAPSGIPGVETMIPLL 319 Query: 63 LNAVHQGRLTIEDLLCR 13 + V + +++I D++ + Sbjct: 320 MGRVLEKKVSIADVIAK 336 >UniRef50_P77884 Cluster: Dihydroorotase; n=25; Bacilli|Rep: Dihydroorotase - Lactobacillus plantarum Length = 430 Score = 58.0 bits (134), Expect = 3e-07 Identities = 25/61 (40%), Positives = 36/61 (59%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +E + A +++A H+CHV+ E + +I+ AK G+ VTCEV PHHL L DI Sbjct: 210 SEAAQVARDVMLAEASGVHYHVCHVSTAESLRVIRNAKAAGINVTCEVSPHHLLLCDEDI 269 Query: 254 T 252 T Sbjct: 270 T 270 Score = 39.9 bits (89), Expect = 0.078 Identities = 27/69 (39%), Positives = 37/69 (53%), Gaps = 4/69 (5%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 64 K+ P L S +D+A L + ID+ ATDHAPHT EK + + G G+ET L Sbjct: 277 KMNPPLRSAKDRAALVAGLLDGTIDMIATDHAPHTDAEKQGSMKTAAFGITGIETAFATL 336 Query: 63 LNAVHQGRL 37 A+ + RL Sbjct: 337 YTALVKTRL 345 Score = 36.7 bits (81), Expect = 0.72 Identities = 20/46 (43%), Positives = 25/46 (54%), Gaps = 1/46 (2%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF-*DLLPQXHWLVVLTMICAMPNTNP 680 PGF+DVHVH+R+PG K L H T + AMPN +P Sbjct: 55 PGFVDVHVHLRDPGQTAKETIATGTLAAAHG--GFTTVGAMPNVDP 98 >UniRef50_Q30X37 Cluster: Dihydroorotase, multifunctional complex type; n=4; Desulfovibrionaceae|Rep: Dihydroorotase, multifunctional complex type - Desulfovibrio desulfuricans (strain G20) Length = 426 Score = 57.6 bits (133), Expect = 4e-07 Identities = 25/56 (44%), Positives = 38/56 (67%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267 AE + A IL+A L PVH+ H++ ++ + +I AK+RGV+VT E CPH+L L+ Sbjct: 214 AESVQVARDILLAEYLGIPVHLAHISCRQSVELIAWAKQRGVRVTAETCPHYLLLD 269 Score = 54.4 bits (125), Expect = 3e-06 Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67 AKV P L +P+D A + R ++ ID+ TDHAPH EK++ + P G GL+T + L Sbjct: 280 AKVNPPLRTPDDVAAMRRAVADGTIDILVTDHAPHAAHEKDTPLDEAPNGISGLDTAVAL 339 Query: 66 LLNAVHQGRLTIEDLL 19 V +G LT D++ Sbjct: 340 TWRLVQEGLLTEADMV 355 >UniRef50_A3ZRV3 Cluster: Dihydroorotase; n=1; Blastopirellula marina DSM 3645|Rep: Dihydroorotase - Blastopirellula marina DSM 3645 Length = 444 Score = 57.2 bits (132), Expect = 5e-07 Identities = 32/76 (42%), Positives = 46/76 (60%), Gaps = 4/76 (5%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPL 67 A++ P L S D A L + + I + ATDHAPH E+K P P G PG+ET LPL Sbjct: 268 AQMNPALKSAADNAALLQALLDDQIQIVATDHAPHRYEDKCQRYPDSPSGVPGVETSLPL 327 Query: 66 LLNAVHQGRLTIEDLL 19 +L+ V + + T+ED++ Sbjct: 328 MLDLVAKEKCTLEDVV 343 Score = 53.6 bits (123), Expect = 6e-06 Identities = 34/102 (33%), Positives = 52/102 (50%), Gaps = 2/102 (1%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644 LPG ID HVH+R+PG K DL +T I MPNT+P+ V + + Sbjct: 51 LPGVIDAHVHMRDPGGTDKE---DLRTGSMAAAKGGVTTILDMPNTSPATVSQKLLEEKL 107 Query: 643 TLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNET 518 TLA V + +Y ++GA+ N + + A + +K+Y+ T Sbjct: 108 TLASVKSIVNYGFFMGATIDNIGEL-KKAKRTPGIKIYMGST 148 Score = 37.9 bits (84), Expect = 0.31 Identities = 26/92 (28%), Positives = 42/92 (45%), Gaps = 7/92 (7%) Frame = -2 Query: 500 EDMTIWQKHFQSWPKKMPVCTHA-----EREKTAA--VILMASLLDRPVHICHVARKEEI 342 ED I K+F+ + V H+ E E +A + +A +H+CH++ Sbjct: 176 EDENIITKNFEEFGLTRNVVDHSRIRTPEAEASAVRKAVALAKEYKHRLHLCHMS---SA 232 Query: 341 LIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246 L + ++ +T EV PHHL LN +D L Sbjct: 233 LALAEFEDHADLITAEVTPHHLLLNESDYMNL 264 >UniRef50_Q28JR7 Cluster: Allantoinase; n=1; Jannaschia sp. CCS1|Rep: Allantoinase - Jannaschia sp. (strain CCS1) Length = 462 Score = 56.8 bits (131), Expect = 6e-07 Identities = 33/83 (39%), Positives = 48/83 (57%), Gaps = 10/83 (12%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSEN-----PPPGYPGLETI 76 AKV P + DQ LW+ I +I+ TDHAP EK + PPG PG+E I Sbjct: 288 AKVNPPIRFQSDQDALWQAIEDGVINYVTTDHAPFAKAEKQASEGDFPGAPPGVPGIEFI 347 Query: 75 LPLLLNAVHQGRLTIE---DLLC 16 +P +L+AV +GRL+++ +L+C Sbjct: 348 VPAMLDAVSRGRLSLKRAHELIC 370 >UniRef50_Q2NHZ6 Cluster: Dihydroorotase; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Dihydroorotase - Methanosphaera stadtmanae (strain DSM 3091) Length = 429 Score = 56.8 bits (131), Expect = 6e-07 Identities = 28/56 (50%), Positives = 35/56 (62%), Gaps = 2/56 (3%) Frame = -1 Query: 180 NISIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILPLLLNAVHQGRLTIEDLL 19 N++ D TDHAPHT+EEK + G PGLET L LLL V+ RLT+E L+ Sbjct: 288 NLNEFDSIGTDHAPHTIEEKEKDTWKSAAGIPGLETALKLLLTEVNNKRLTLEQLV 343 Score = 47.2 bits (107), Expect = 5e-04 Identities = 31/102 (30%), Positives = 51/102 (50%) Frame = -3 Query: 829 NIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDY 650 NI+ +PG ID HVH+R+PG K + Q T I MPNT P+ + AF Sbjct: 49 NII-IPGLIDTHVHLRDPGMTQKETW-TTGTQAAAHGGYTTIIDMPNTLPATDTKKAFQE 106 Query: 649 ASTLARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLN 524 +A + D+ L+ G T D + ++ + A+ K++++ Sbjct: 107 KRNIATKKSYVDFGLHAGV-KTRQDVMDIMSEKPASYKIFMD 147 Score = 39.1 bits (87), Expect = 0.14 Identities = 13/38 (34%), Positives = 28/38 (73%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264 +H+CH++ ++ + +I AKE+ + ++ E PHH+FL++ Sbjct: 225 LHLCHISTRQTLELIHEAKEK-LNISIEATPHHIFLDN 261 >UniRef50_Q5HGN1 Cluster: Dihydroorotase; n=14; Bacillales|Rep: Dihydroorotase - Staphylococcus aureus (strain COL) Length = 424 Score = 56.8 bits (131), Expect = 6e-07 Identities = 25/59 (42%), Positives = 35/59 (59%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 E + A +L+A H+CHV+ KE + +I+ AK G+ VT EV PHHL L +DI Sbjct: 208 ESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDI 266 Score = 44.8 bits (101), Expect = 0.003 Identities = 31/76 (40%), Positives = 39/76 (51%), Gaps = 5/76 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 64 K+ P L S ED+ L + ID ATDHAPH +EK E P G G ET PLL Sbjct: 274 KMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLL 333 Query: 63 -LNAVHQGRLTIEDLL 19 + V G T++ L+ Sbjct: 334 YTHFVKNGDWTLQQLV 349 Score = 41.9 bits (94), Expect = 0.019 Identities = 20/45 (44%), Positives = 25/45 (55%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP 680 PGF+DVHVH+REPG K + + T +C MPNT P Sbjct: 52 PGFVDVHVHLREPGGEYKETI-ETGTKAAARGGFTTVCPMPNTRP 95 >UniRef50_A5ULX4 Cluster: Dihydroorotase, PyrC; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Dihydroorotase, PyrC - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 414 Score = 56.4 bits (130), Expect = 8e-07 Identities = 30/65 (46%), Positives = 42/65 (64%), Gaps = 5/65 (7%) Frame = -1 Query: 207 PEDQAELWRNISIID---VFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQG 43 P +A+ NIS ID + TDHAPHT+E+KN + PG P LET++PLLL V++G Sbjct: 272 PLREAKYKINISDIDENTIIGTDHAPHTLEDKNQGVWSSSPGIPALETVVPLLLTQVNRG 331 Query: 42 RLTIE 28 L ++ Sbjct: 332 NLDLK 336 Score = 39.9 bits (89), Expect = 0.078 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 1/110 (0%) Frame = -3 Query: 838 VHGNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTA 659 + GN++ LPGFID HVH R+PG K F + T + MPNT P A Sbjct: 42 IKGNLL-LPGFIDPHVHFRDPGLTQKEDF-KTGSESAANGGFTTVIDMPNTIPKTNTYDA 99 Query: 658 FDYASTLARVSARCDYALYVGASS-TNYDTICELAPQAAALKMYLNETFT 512 +A + +Y L G ++ + I L P A + M L + T Sbjct: 100 LKEKIAIADEKSIVNYELQAGWNTLEEMEKIISLNPIAFKVFMDLEDNET 149 >UniRef50_A5UX77 Cluster: Dihydroorotase, multifunctional complex type; n=3; Chloroflexaceae|Rep: Dihydroorotase, multifunctional complex type - Roseiflexus sp. RS-1 Length = 497 Score = 56.0 bits (129), Expect = 1e-06 Identities = 26/55 (47%), Positives = 34/55 (61%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 AE A I +A + +HICHV+ + +I+AAK RGV+VT EV PHHL L Sbjct: 217 AEEAMVARDIALAEMTGAHLHICHVSTAGSVALIRAAKARGVRVTAEVTPHHLTL 271 Score = 40.7 bits (91), Expect = 0.045 Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 4/77 (5%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILPLL 64 +V P L + +D L + ID A+DH P + +K E G LET L L Sbjct: 324 RVRPPLRTEQDVEALIEGLRDGTIDAIASDHEPQSAVDKECEYRLAASGISSLETALGLA 383 Query: 63 LNAVHQGRLTIEDLLCR 13 L VH+G+L + DL+ + Sbjct: 384 LTLVHRGKLDLVDLVAK 400 Score = 39.5 bits (88), Expect = 0.10 Identities = 19/47 (40%), Positives = 25/47 (53%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSI 674 PGF+D+H HVREPG K + + T +C MP+T P I Sbjct: 62 PGFLDLHAHVREPGEEHKETI-ETATKAAAAGGFTTLCVMPDTRPPI 107 >UniRef50_Q984Y5 Cluster: Dihydroorotase; n=50; cellular organisms|Rep: Dihydroorotase - Rhizobium loti (Mesorhizobium loti) Length = 489 Score = 55.6 bits (128), Expect = 1e-06 Identities = 25/58 (43%), Positives = 40/58 (68%), Gaps = 4/58 (6%) Frame = -1 Query: 189 LWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETILPLLLNAVHQGRLTIE 28 +W I+ I+DV +DHAPHT+ EK P P G G++T++P++L+ V+ GRLT++ Sbjct: 335 VWHGIAQGIVDVLGSDHAPHTLAEKAKPYPASPSGMTGVQTLVPIMLDHVNAGRLTLQ 392 Score = 50.0 bits (114), Expect = 7e-05 Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 4/104 (3%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638 LPG +D VH REPG K + + L +T + MPNTNP A + Sbjct: 101 LPGVVDSQVHFREPGLEHKEDL-ETGSRAAVLGGVTAVFEMPNTNPLTTSEATL--ADKV 157 Query: 637 ARVSAR--CDYALYVGASSTNYDTICEL--APQAAALKMYLNET 518 R S R CD+A +VG + N + EL P AA +K+++ + Sbjct: 158 RRGSGRMHCDFAFWVGGTRDNARDVGELERLPGAAGIKVFMGSS 201 Score = 41.1 bits (92), Expect = 0.034 Identities = 19/58 (32%), Positives = 34/58 (58%) Frame = -2 Query: 419 TAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246 T ++ +A + +H+ H++ EEIL ++ K+ TCE PHHL L+++D +L Sbjct: 262 TERLVRIARDVRARIHVLHISTAEEILFLEQHKD---VATCEATPHHLTLSADDYLRL 316 >UniRef50_Q73ID8 Cluster: Dihydroorotase; n=15; Rickettsiales|Rep: Dihydroorotase - Wolbachia pipientis wMel Length = 459 Score = 55.2 bits (127), Expect = 2e-06 Identities = 31/82 (37%), Positives = 47/82 (57%), Gaps = 4/82 (4%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67 AK+ P L + ED+ + + +ID ATDHAPH K+ EN G GLET+LPL Sbjct: 309 AKMNPPLRTEEDRLAMVEGLKTGVIDCIATDHAPHDRSSKDLPLENAAFGIVGLETMLPL 368 Query: 66 LLNAVHQGRLTIEDLLCRIRHE 1 L H G++ + D+L ++ ++ Sbjct: 369 SLELYHSGQMGLLDVLAKLTYK 390 Score = 50.0 bits (114), Expect = 7e-05 Identities = 24/54 (44%), Positives = 34/54 (62%) Frame = -2 Query: 410 VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITK 249 ++LM + + HI HV+ K+ + IK AK+ G+ VTCEV PHH F + DI K Sbjct: 251 ILLMKDMENVHYHILHVSSKDSLDAIKRAKDLGLNVTCEVTPHH-FTLTEDIVK 303 Score = 38.3 bits (85), Expect = 0.24 Identities = 27/90 (30%), Positives = 41/90 (45%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 +V +PG ID+HVH REPG K V T++C PNT P+I Y Sbjct: 85 LVLMPGLIDIHVHFREPGQEHKETIYTGSKSAAAGGVTTVVC-QPNTVPAIDSVILAKYL 143 Query: 646 STLARVSARCDYALYVGASSTNYDTICELA 557 A ++ + Y +T+ + + E+A Sbjct: 144 KYRALETSHVNVEFY-AKITTSEEHLTEMA 172 >UniRef50_Q5FPJ5 Cluster: Dihydroorotase; n=4; Proteobacteria|Rep: Dihydroorotase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 439 Score = 55.2 bits (127), Expect = 2e-06 Identities = 33/98 (33%), Positives = 49/98 (50%), Gaps = 2/98 (2%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638 LPG ID HVH+R+PG + + L + + MPNT+PS+ D T D+ Sbjct: 53 LPGLIDAHVHLRDPGKPEVETL-ETGTRAAALGGIATVFDMPNTSPSVTDVTMIDWKRDH 111 Query: 637 ARVSARCDYALYVGASSTNYDTIC--ELAPQAAALKMY 530 R +A D +YVGA+ N + E P A+K++ Sbjct: 112 IRKTAHVDVGIYVGATRENTPDLATLEQQPGVCAVKVF 149 Score = 48.8 bits (111), Expect = 2e-04 Identities = 30/82 (36%), Positives = 46/82 (56%), Gaps = 4/82 (4%) Frame = -1 Query: 252 KIGKGRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENP--PPGYPGL 85 K+G G A + P L WR + +DV ++DHAPH +E K P P G G Sbjct: 269 KLG-GLAVMNPPLRDRSHWEASWRAVRDGRVDVVSSDHAPHPLEAKKLPWPKCPAGLTGT 327 Query: 84 ETILPLLLNAVHQGRLTIEDLL 19 +TI+P++L+ V+ GRL++ L+ Sbjct: 328 QTIVPVMLDHVNAGRLSLARLV 349 >UniRef50_Q4QEW1 Cluster: Dihydroorotase, putative; n=9; Trypanosomatidae|Rep: Dihydroorotase, putative - Leishmania major Length = 405 Score = 55.2 bits (127), Expect = 2e-06 Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 6/74 (8%) Frame = -1 Query: 255 YKIGKGRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKN----SENPPPGY 94 Y R KV P + P+ LW + +D TDHAPHT+ EK+ + PP G Sbjct: 243 YSCCGARVKVNPPVRPPQHHEALWAGLLDGTVDCVGTDHAPHTIAEKDHCDAAAQPPSGM 302 Query: 93 PGLETILPLLLNAV 52 P +E ++PLLL V Sbjct: 303 PAIEVVVPLLLTVV 316 Score = 45.6 bits (103), Expect = 0.002 Identities = 20/61 (32%), Positives = 37/61 (60%), Gaps = 2/61 (3%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAK--ERGVKVTCEVCPHHLFLNSN 261 +E + I +A P+H+ HV+ + + +I+ A+ + +++TCEV PHHLFL ++ Sbjct: 182 SEAASVQSAIALARQCRTPLHLAHVSTAQSLDLIREARAADPTLQLTCEVTPHHLFLTTS 241 Query: 260 D 258 D Sbjct: 242 D 242 Score = 43.6 bits (98), Expect = 0.006 Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 2/82 (2%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP--SIVDRTAFD 653 +V+LP ID HVH REPG K ++ +T+ C MPNT+P V A Sbjct: 11 VVQLPPLIDCHVHFREPGLEHKADIASESTAAYY-GGITVACDMPNTSPPTQSVAALADK 69 Query: 652 YASTLARVSARCDYALYVGASS 587 A A A C + GA++ Sbjct: 70 VARAKATAHAHCQLFFFFGATA 91 >UniRef50_Q74DP4 Cluster: Dihydroorotase, multifunctional complex type; n=8; Bacteria|Rep: Dihydroorotase, multifunctional complex type - Geobacter sulfurreducens Length = 425 Score = 54.8 bits (126), Expect = 3e-06 Identities = 25/60 (41%), Positives = 35/60 (58%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE TA + +A + P+HI HV+ + II+ AK RGVKVTCE PH+ L + + Sbjct: 210 AEDAATARDVYLAEFTNSPLHIAHVSTMGSLRIIRNAKARGVKVTCETAPHYFSLTDDAV 269 Score = 48.4 bits (110), Expect = 2e-04 Identities = 33/76 (43%), Positives = 44/76 (57%), Gaps = 4/76 (5%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE-NPP-PGYPGLETILPL 67 AK+ P L + +D A + + ID ATDHAPH ++EK+ E N G GLET LPL Sbjct: 276 AKMNPPLRTADDLAAVKEALKDGTIDAIATDHAPHHLDEKDVEFNVALNGIIGLETSLPL 335 Query: 66 LLNAVHQGRLTIEDLL 19 L V +G LT+ L+ Sbjct: 336 SLKLVEEGVLTLPALV 351 Score = 35.9 bits (79), Expect = 1.3 Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 2/67 (2%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFD 653 ++ PG ID+HVH+R+PG K D++ T + MPNT P ++ Sbjct: 51 LIVTPGLIDMHVHLRDPGLEYKE---DIVTGTRAAAAGGFTSVACMPNTKPVNDNKAVTS 107 Query: 652 YASTLAR 632 Y A+ Sbjct: 108 YIVAKAK 114 >UniRef50_P25995 Cluster: Dihydroorotase; n=41; Bacteria|Rep: Dihydroorotase - Bacillus subtilis Length = 428 Score = 54.8 bits (126), Expect = 3e-06 Identities = 20/44 (45%), Positives = 31/44 (70%) Frame = -2 Query: 374 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLE 243 H+CH++ KE + +++ AK+ G++VT EV PHHL L DI L+ Sbjct: 227 HVCHISTKESVRVVRDAKKAGIRVTAEVSPHHLLLCDEDIPGLD 270 Score = 46.4 bits (105), Expect = 9e-04 Identities = 24/42 (57%), Positives = 28/42 (66%), Gaps = 2/42 (4%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE 112 K+ P L SPED+A L + ID ATDHAPHT EEKN+E Sbjct: 274 KMNPPLRSPEDRAALIEGLLDGTIDFIATDHAPHTEEEKNTE 315 Score = 37.5 bits (83), Expect = 0.41 Identities = 19/45 (42%), Positives = 24/45 (53%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP 680 PGF+D+HVH REPG K + + T + AMPNT P Sbjct: 53 PGFVDLHVHFREPGGEKKETI-ETGAKAAGRGGYTTVAAMPNTRP 96 >UniRef50_Q9PEP0 Cluster: Dihydroorotase; n=54; cellular organisms|Rep: Dihydroorotase - Xylella fastidiosa Length = 449 Score = 54.4 bits (125), Expect = 3e-06 Identities = 37/100 (37%), Positives = 49/100 (49%), Gaps = 3/100 (3%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644 LPG ID VH REPG KG D+ + V LT MPNTNP +D A Sbjct: 53 LPGMIDDQVHFREPGLTHKG---DIASESAAAVAGGLTSFMDMPNTNPPTLDVAALQAKY 109 Query: 643 TLARVSARCDYALYVGASSTNYDTICELAPQAA-ALKMYL 527 A A +Y Y+GAS+ N I L P+ + +K+++ Sbjct: 110 DAASGRAWGNYGFYLGASNDNLAAIQALDPKTSPGIKVFM 149 Score = 51.6 bits (118), Expect = 2e-05 Identities = 25/58 (43%), Positives = 34/58 (58%), Gaps = 2/58 (3%) Frame = -1 Query: 171 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRIRH 4 +IDV ATDHAPHT EEK P G P ++ L L VH GRL++ +++ + H Sbjct: 308 VIDVLATDHAPHTWEEKQQPYAQAPSGLPLVQYALVAALELVHAGRLSVTEIVRKFAH 365 >UniRef50_Q3AC01 Cluster: Dihydroorotase; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: Dihydroorotase - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 430 Score = 54.4 bits (125), Expect = 3e-06 Identities = 34/79 (43%), Positives = 46/79 (58%), Gaps = 5/79 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64 KV P L E+Q L + + +IDV ATDHAPH EKN E + P G GLET P+L Sbjct: 275 KVNPPLREAEEQKALLKGLLEGVIDVIATDHAPHASYEKNVEFNDAPFGIEGLETAFPVL 334 Query: 63 -LNAVHQGRLTIEDLLCRI 10 V + ++T+E LL ++ Sbjct: 335 YTELVLKKKITLEKLLLKM 353 Score = 45.6 bits (103), Expect = 0.002 Identities = 19/46 (41%), Positives = 30/46 (65%) Frame = -2 Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 I +A + +H+ H++ E + ++ AAK+ G+KVT EV PHHL L Sbjct: 217 IEIAKMTGAKLHVAHLSTAEGVRLVAAAKKLGLKVTAEVTPHHLVL 262 >UniRef50_Q2RGZ6 Cluster: D-hydantoinase; n=1; Moorella thermoacetica ATCC 39073|Rep: D-hydantoinase - Moorella thermoacetica (strain ATCC 39073) Length = 454 Score = 54.0 bits (124), Expect = 4e-06 Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 7/77 (9%) Frame = -1 Query: 228 VCPVLCSPEDQAELWRNISIID--VFATDHAPHTVEEKNSE----NPPPGYPGLETILPL 67 +CP L + +D LW++++ D V ATDH ++ E+K + N P G PG ET+LPL Sbjct: 283 MCPPLRTVKDNRILWQHLASGDLQVVATDHCSYSPEQKAAGTAFYNTPSGVPGTETLLPL 342 Query: 66 LLN-AVHQGRLTIEDLL 19 L + V QGRLT+ ++ Sbjct: 343 LYSYGVRQGRLTLPQMV 359 Score = 40.3 bits (90), Expect = 0.059 Identities = 22/55 (40%), Positives = 30/55 (54%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 AE + VI A+ PV+I HV+ +I AA+ RG +V E CPH+L L Sbjct: 214 AEVKAIEKVIRQAAAAGAPVYIVHVSTGGGAELIAAARARGQQVFGETCPHYLLL 268 >UniRef50_P07259 Cluster: Protein URA1 [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2)]; n=133; cellular organisms|Rep: Protein URA1 [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Aspartate carbamoyltransferase (EC 2.1.3.2)] - Saccharomyces cerevisiae (Baker's yeast) Length = 2214 Score = 54.0 bits (124), Expect = 4e-06 Identities = 24/69 (34%), Positives = 41/69 (59%) Frame = -2 Query: 464 WPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCP 285 WP + V A+ A+V+L+ SL +R +HI V+ KE++ +I K + +VTC+V Sbjct: 1623 WPTEKQVIAEAKTADLASVLLLTSLQNRSIHITGVSNKEDLALIMTVKAKDPRVTCDVNI 1682 Query: 284 HHLFLNSND 258 + LF+ +D Sbjct: 1683 YSLFIAQDD 1691 Score = 48.0 bits (109), Expect = 3e-04 Identities = 25/69 (36%), Positives = 37/69 (53%) Frame = -1 Query: 216 LCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRL 37 L + EDQ W N+ ID F+ P + G G++ LPLLL AV +G+L Sbjct: 1698 LPTKEDQEFFWNNLDSIDAFSVGALPVALANVTGNKVDVGM-GIKDSLPLLLAAVEEGKL 1756 Query: 36 TIEDLLCRI 10 TI+D++ R+ Sbjct: 1757 TIDDIVLRL 1765 >UniRef50_Q0LDY3 Cluster: Dihydroorotase; n=2; Chloroflexi (class)|Rep: Dihydroorotase - Herpetosiphon aurantiacus ATCC 23779 Length = 473 Score = 53.6 bits (123), Expect = 6e-06 Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 4/80 (5%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSEN--PPPGYPGLETILP 70 R +V P L + ED A L + ID ATDHAPHT +K E PG+ GLE LP Sbjct: 298 RTRVSPPLRTSEDVAALIAGLRDGTIDAVATDHAPHTHVDKECEYGFASPGFTGLELALP 357 Query: 69 LLLNAVHQGRLTIEDLLCRI 10 ++L V ++ I +L+ R+ Sbjct: 358 MVLTLVQTMQIDIVELISRM 377 Score = 47.6 bits (108), Expect = 4e-04 Identities = 24/52 (46%), Positives = 31/52 (59%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 276 E A I +A +HICHV+ + +I+AAK RGV+VT EV PHHL Sbjct: 216 EEVMIARDIALAEETGGRLHICHVSTAGGVELIRAAKARGVRVTGEVTPHHL 267 Score = 42.7 bits (96), Expect = 0.011 Identities = 33/97 (34%), Positives = 46/97 (47%), Gaps = 7/97 (7%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV---LTMICAMPNTNPSI----VDRTAF 656 PGFID+H H+REPG +G+ + + V T IC MPNTNPS+ + R F Sbjct: 60 PGFIDIHTHLREPG--FEGK--ETIATGMDAAVRGGYTTICPMPNTNPSLDSAPLIRQQF 115 Query: 655 DYASTLARVSARCDYALYVGASSTNYDTICELAPQAA 545 D A+ + A+ +G + ELA A Sbjct: 116 DIAARHGPIHVLPIGAVTLGREGKVLAPLVELAEAGA 152 >UniRef50_A4GJR5 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihydroorotase - uncultured marine bacterium HF10_45G01 Length = 435 Score = 53.6 bits (123), Expect = 6e-06 Identities = 25/76 (32%), Positives = 43/76 (56%), Gaps = 4/76 (5%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67 A++ P L LW + + D +DHAPH E K+ N P G PG++T++P+ Sbjct: 271 AQMNPPLRDKSHYDRLWYGVRNNFNDTIGSDHAPHLKENKDKVYPNTPSGMPGVQTLMPV 330 Query: 66 LLNAVHQGRLTIEDLL 19 +LN ++ G+L++ L+ Sbjct: 331 MLNHINNGKLSLNQLI 346 Score = 46.8 bits (106), Expect = 7e-04 Identities = 30/88 (34%), Positives = 40/88 (45%), Gaps = 2/88 (2%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644 LPG ID H REPG+ DL + +T + MPNTNP + F Sbjct: 51 LPGCIDTQTHFREPGSTDTE---DLHSGSRAAIAGGITSVFEMPNTNPPTSNMKEFQRKL 107 Query: 643 TLARVSARCDYALYVGASSTNYDTICEL 560 LA+ +YA Y GA++ N D + L Sbjct: 108 DLAKNRMYSNYAFYFGATADNADDLASL 135 >UniRef50_A4ECL5 Cluster: Dihydroorotase; n=1; Collinsella aerofaciens ATCC 25986|Rep: Dihydroorotase - Collinsella aerofaciens ATCC 25986 Length = 429 Score = 53.6 bits (123), Expect = 6e-06 Identities = 24/59 (40%), Positives = 35/59 (59%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 E + A I +A L +HI H++ + I++A K GV+VTCE PHH+FL ND+ Sbjct: 210 EELQIARDIEIAKLTGAKLHIQHISTAHGLEIVRAGKAAGVQVTCEATPHHMFLTENDL 268 Score = 44.0 bits (99), Expect = 0.005 Identities = 22/67 (32%), Positives = 35/67 (52%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638 +PG +D+HVH+REPG +K + + T +CAMPNT+P + T ++ + Sbjct: 53 VPGLVDMHVHLREPGYEVKEDI-ESGTRAAAKGGFTGVCAMPNTDPVTDNGTVVEFVKSR 111 Query: 637 ARVSARC 617 A C Sbjct: 112 AAEVGHC 118 Score = 40.7 bits (91), Expect = 0.045 Identities = 28/72 (38%), Positives = 39/72 (54%), Gaps = 5/72 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 64 KV P L + ED + + + +D TDHAPHT EK E P G GLET L L+ Sbjct: 277 KVNPPLRTEEDAEAIRQGVIDGTVDAIVTDHAPHTPWEKAREFELAPFGMIGLETSLSLV 336 Query: 63 L-NAVHQGRLTI 31 L V+ G++++ Sbjct: 337 LTELVNTGKMSM 348 >UniRef50_Q8XL61 Cluster: Dihydroorotase; n=12; Bacteria|Rep: Dihydroorotase - Clostridium perfringens Length = 399 Score = 53.2 bits (122), Expect = 8e-06 Identities = 26/57 (45%), Positives = 34/57 (59%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264 AE T I +A +D +H+ HV+ KE + I K GVKVTCE+ PHHL LN+ Sbjct: 191 AENMMTWRDITLAKFVDCRLHMSHVSTKEAMKYIIEGKNDGVKVTCEITPHHLALNN 247 Score = 34.3 bits (75), Expect = 3.9 Identities = 19/59 (32%), Positives = 26/59 (44%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDY 650 +V +P FID H H R+PG K + + T + MPNT P + DY Sbjct: 47 LVLMPAFIDTHAHFRDPGFEYKEDI-ESGSKAAVRGGYTTVTLMPNTKPVCSSKEILDY 104 >UniRef50_Q89PZ7 Cluster: D-hydantoinase; n=5; Alphaproteobacteria|Rep: D-hydantoinase - Bradyrhizobium japonicum Length = 489 Score = 53.2 bits (122), Expect = 8e-06 Identities = 24/62 (38%), Positives = 40/62 (64%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +E E +I MA+L+D+P+ I HV+ E +I+ ++ +G+KV E CP +LFL + D+ Sbjct: 220 SEAEAFTRLIGMAALIDQPIMIFHVSTAEGAKVIRDSRGQGLKVFAETCPQYLFLTAADL 279 Query: 254 TK 249 K Sbjct: 280 DK 281 Score = 41.5 bits (93), Expect = 0.025 Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 17/80 (21%) Frame = -1 Query: 216 LCSPE-----DQAELWRNISIIDV--FATDHAPHTVEE--KNSENPPP-------GYPGL 85 +CSP DQ LW+ +S+ D+ ++DHAP+ +E K P P G PGL Sbjct: 290 MCSPPPRTHADQEALWQALSLGDLQTISSDHAPYRFDETGKLRAGPNPNFKQVANGLPGL 349 Query: 84 ETILPLLLNA-VHQGRLTIE 28 E LPLL +A V +GRL +E Sbjct: 350 ELRLPLLFDAMVSKGRLGLE 369 >UniRef50_Q6U5R7 Cluster: PyrC; n=6; Gammaproteobacteria|Rep: PyrC - Klebsiella pneumoniae Length = 448 Score = 53.2 bits (122), Expect = 8e-06 Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 4/82 (4%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 70 + K P + + Q LW+ ++ IIDV ATDHAPH +EEK S+ P G P ++ LP Sbjct: 282 KLKCNPSVKTSFHQEALWKGVNEGIIDVIATDHAPHLLEEKQSDYFAAPSGLPLVQHALP 341 Query: 69 LLLNAVHQGRLTIEDLLCRIRH 4 LL+ +G T E ++ + H Sbjct: 342 ALLDMCSRGIFTPEMVVRKTSH 363 Score = 47.2 bits (107), Expect = 5e-04 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 3/100 (3%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644 +PG ID VH REPG KG + + V+ +T MPN P R A Sbjct: 53 IPGMIDDQVHFREPGLTHKG---TIATESAAAVMGGITSFMEMPNVTPPTTTRQALREKF 109 Query: 643 TLARVSARCDYALYVGASSTNYDTICEL-APQAAALKMYL 527 A S+ +++ Y GA++ N D + L A QA +K+++ Sbjct: 110 QRASRSSLANHSFYFGATNDNLDELKALTASQACGVKVFM 149 Score = 35.5 bits (78), Expect = 1.7 Identities = 16/48 (33%), Positives = 25/48 (52%), Gaps = 4/48 (8%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKE----RGVKVTCEVCPHHLFLNSNDITKL 246 +H+ H+ +E+++ AA R +T E C HHLF N +D L Sbjct: 232 LHVLHITTADELVLFDAAPTLEALRQKTITAEACVHHLFFNYDDYETL 279 >UniRef50_Q1VNG2 Cluster: Dihydroorotase; n=2; Psychroflexus torquis ATCC 700755|Rep: Dihydroorotase - Psychroflexus torquis ATCC 700755 Length = 441 Score = 53.2 bits (122), Expect = 8e-06 Identities = 28/77 (36%), Positives = 44/77 (57%), Gaps = 4/77 (5%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP--PPGYPGLETILP 70 R ++ P + +D+ LW+ + + ATDHAPHT+E K P P G PG+ET L Sbjct: 264 RLQMNPPVRYKKDRETLWKQLKSGTVQCIATDHAPHTLEAKALGFPKAPSGMPGVETSLA 323 Query: 69 LLLNAVHQGRLTIEDLL 19 ++L + G +IED++ Sbjct: 324 VMLTHANDGACSIEDVV 340 Score = 33.9 bits (74), Expect = 5.1 Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 2/81 (2%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644 LPG ID VH R+PG K DL V +T MPN PSI + Sbjct: 28 LPGMIDPQVHFRDPGQPEKE---DLGSGSAAAVSGGITSFLDMPNNKPSITTLEGMNMKL 84 Query: 643 TLARVSARCDYALYVGASSTN 581 A +Y ++GA+ N Sbjct: 85 KTASEKCVNNYGFFIGATPDN 105 >UniRef50_A5NZP0 Cluster: Dihydropyrimidinase; n=5; Proteobacteria|Rep: Dihydropyrimidinase - Methylobacterium sp. 4-46 Length = 503 Score = 53.2 bits (122), Expect = 8e-06 Identities = 26/61 (42%), Positives = 37/61 (60%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 ERE T I +A L+D+P+ I HV+ E I A+ RGVKV E CP +L L++ D+ Sbjct: 224 EREATHRAIALAELVDQPIQIFHVSCDEAAEEIARARARGVKVWGETCPQYLTLSTEDLA 283 Query: 251 K 249 + Sbjct: 284 R 284 >UniRef50_Q7NEQ6 Cluster: Dihydroorotase; n=1; Gloeobacter violaceus|Rep: Dihydroorotase - Gloeobacter violaceus Length = 407 Score = 52.8 bits (121), Expect = 1e-05 Identities = 31/67 (46%), Positives = 38/67 (56%), Gaps = 4/67 (5%) Frame = -1 Query: 222 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNA 55 P L +P D+A L + IID A+DH P T EEK PPG LE +LPL+ N Sbjct: 279 PPLGNPADRAALVAALEAGIIDAVASDHTPWTYEEKTLPFSQAPPGAIALELVLPLVWNL 338 Query: 54 VHQGRLT 34 V +GRLT Sbjct: 339 VREGRLT 345 >UniRef50_Q8KDK5 Cluster: Dihydroorotase; n=10; Chlorobiaceae|Rep: Dihydroorotase - Chlorobium tepidum Length = 439 Score = 52.8 bits (121), Expect = 1e-05 Identities = 20/47 (42%), Positives = 32/47 (68%), Gaps = 1/47 (2%) Frame = -2 Query: 374 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI-TKLEKG 237 H+ H++ E + +++ AK G+KVTCEV PHH L +D+ + +EKG Sbjct: 243 HVAHISTAESVALVRKAKAAGLKVTCEVTPHHFTLTEHDLSSSIEKG 289 Score = 39.1 bits (87), Expect = 0.14 Identities = 32/84 (38%), Positives = 41/84 (48%), Gaps = 7/84 (8%) Frame = -1 Query: 249 IGKGRAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENPPP----GYPG 88 I KG + P L S E++ L + ID ATDHAPH EK E PP G G Sbjct: 286 IEKGNFIMKPPLASVENRDALIEGLRDGTIDAIATDHAPHAKHEK--ECPPDQAAFGIIG 343 Query: 87 LETILPL-LLNAVHQGRLTIEDLL 19 LET L L + V +G +T+ + Sbjct: 344 LETSLGLTITELVDKGVITLSQAI 367 >UniRef50_Q9KAH8 Cluster: Allantoinase; n=1; Bacillus halodurans|Rep: Allantoinase - Bacillus halodurans Length = 438 Score = 52.4 bits (120), Expect = 1e-05 Identities = 22/63 (34%), Positives = 37/63 (58%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +E E ++ A L P+HICHV+ ++ + IK AK GV V+ E CPH+L + ++ Sbjct: 219 SELEAVERILRFAQLTCCPIHICHVSSRKVLKRIKQAKGEGVNVSVETCPHYLLFSLDEF 278 Query: 254 TKL 246 ++ Sbjct: 279 AEI 281 Score = 38.3 bits (85), Expect = 0.24 Identities = 26/85 (30%), Positives = 33/85 (38%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTLA 635 PG +DVHVH EPG F V T N+NP + R D LA Sbjct: 57 PGMVDVHVHFNEPGRTEWEGFASGSKSLAAGGVTTYFDMPLNSNPPTITREELDKKRQLA 116 Query: 634 RVSARCDYALYVGASSTNYDTICEL 560 + DY + G N D + +L Sbjct: 117 NEKSLVDYRFWGGLVPGNIDHLQDL 141 >UniRef50_Q8AB61 Cluster: Dihydroorotase; n=3; Bacteroides|Rep: Dihydroorotase - Bacteroides thetaiotaomicron Length = 445 Score = 52.4 bits (120), Expect = 1e-05 Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 3/103 (2%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644 LPG ID HVH R+PG K D+ + H +T I MPNTNP A + Sbjct: 55 LPGAIDEHVHFRDPGLTHKA---DITTESHAAAAGGVTSIMDMPNTNPQTTTLEALNDKL 111 Query: 643 TLARVSARCDYALYVGASSTNYDTICEL-APQAAALKMYLNET 518 L + +++ Y GA++ NY +L + +K+++ + Sbjct: 112 ALLAEKSSVNFSCYFGATNNNYPLFSQLDKNRVCGVKLFMGSS 154 Score = 43.6 bits (98), Expect = 0.006 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 4/88 (4%) Frame = -1 Query: 255 YKIGKGRAKVCPVLCSPEDQAELWR--NISIIDVFATDHAPHTVEEK--NSENPPPGYPG 88 Y+ R K P + + ED+ L N +ID ATDHAPH++ EK + G P Sbjct: 274 YQTLGARIKCNPAIKTAEDRKALQEAVNSGLIDAIATDHAPHSLSEKEGGALKVMSGMPT 333 Query: 87 LETILPLLLNAVHQGRLTIEDLLCRIRH 4 ++ L +L +G +IE ++ ++ H Sbjct: 334 IQFSLVSMLELADKGAFSIEKVVEKMSH 361 >UniRef50_Q2KXE6 Cluster: D-hydantoinase; n=2; Proteobacteria|Rep: D-hydantoinase - Bordetella avium (strain 197N) Length = 499 Score = 52.4 bits (120), Expect = 1e-05 Identities = 26/59 (44%), Positives = 36/59 (61%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 258 AE E T I ++ LLD PV I HVA + + II+ A++ G +V E CP +LFL + D Sbjct: 225 AESEATHRAIALSRLLDVPVLIVHVAGAQTVDIIRRARQLGAQVYAESCPQYLFLEATD 283 >UniRef50_A4XKT2 Cluster: Dihydroorotase, multifunctional complex type; n=1; Caldicellulosiruptor saccharolyticus DSM 8903|Rep: Dihydroorotase, multifunctional complex type - Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) Length = 430 Score = 52.4 bits (120), Expect = 1e-05 Identities = 25/60 (41%), Positives = 35/60 (58%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE A IL+A +HI HV+ KE + +IK AKE GV VT + CPH++ L ++ Sbjct: 210 AESVIIARDILLAKETKSHLHITHVSTKESVRLIKMAKEWGVNVTADTCPHYISLTEEEV 269 Score = 44.0 bits (99), Expect = 0.005 Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 2/66 (3%) Frame = -3 Query: 823 VKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDY 650 V +P F D+H H+REPG K D+ T IC MPNTNP + +R Y Sbjct: 52 VVMPSFTDIHCHLREPGFEYKE---DIKSGSRSAAAGGFTTICCMPNTNPPVDNRAMVAY 108 Query: 649 ASTLAR 632 AR Sbjct: 109 IKYRAR 114 Score = 37.1 bits (82), Expect = 0.55 Identities = 25/61 (40%), Positives = 31/61 (50%), Gaps = 4/61 (6%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67 AKV P L + ED L + +ID +TDHAPH +EKN E G G ET + Sbjct: 276 AKVNPPLRTQEDVEALIEGLKEGVIDCISTDHAPHHKDEKNVEFNLAASGTIGFETAFSV 335 Query: 66 L 64 L Sbjct: 336 L 336 >UniRef50_O27199 Cluster: Dihydroorotase; n=2; Methanothermobacter thermautotrophicus str. Delta H|Rep: Dihydroorotase - Methanobacterium thermoautotrophicum Length = 431 Score = 52.4 bits (120), Expect = 1e-05 Identities = 23/51 (45%), Positives = 33/51 (64%), Gaps = 2/51 (3%) Frame = -1 Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDL 22 I++ TDHAPH +EEK + PPG P LE +L LLL V +GR+++ + Sbjct: 284 INIIGTDHAPHGIEEKRKGIWDAPPGIPNLEVVLKLLLTLVSKGRMSLSTI 334 Score = 46.8 bits (106), Expect = 7e-04 Identities = 22/57 (38%), Positives = 35/57 (61%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264 AE A V+ ++ + PVHICH++ + + +++ +E VTCEV PHHL L+S Sbjct: 200 AEEVSVAEVLALSIHHEHPVHICHLSTVKALQLVEPFREY---VTCEVTPHHLLLDS 253 Score = 39.1 bits (87), Expect = 0.14 Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF-*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYAST 641 LPG ID HVH R+PG K F + H + + MPNT P + F+ Sbjct: 48 LPGLIDAHVHFRDPGLEYKEDFRTGSMAAAHG--GFSTVLDMPNTVPPADNAAEFERKIR 105 Query: 640 LARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNET 518 + + D+ L+ G S + D L A+ K++++ T Sbjct: 106 IGERKSVVDFGLHAGFRSVS-DVKGILRFMPASFKVFMDLT 145 >UniRef50_Q0UHH4 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 512 Score = 51.6 bits (118), Expect = 2e-05 Identities = 24/70 (34%), Positives = 41/70 (58%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE E + I +A L+D P+ I H++ + + ++AA+ R + V E CPH+LFL S +I Sbjct: 225 AEDEASYRAISLAELVDAPILIVHMSSEAAVEHVRAAQARLLPVHAETCPHYLFLLSEEI 284 Query: 254 TKLEKGEQKY 225 + G+ + Sbjct: 285 KQCHHGDNSH 294 >UniRef50_O66990 Cluster: Dihydroorotase; n=1; Aquifex aeolicus|Rep: Dihydroorotase - Aquifex aeolicus Length = 422 Score = 51.6 bits (118), Expect = 2e-05 Identities = 31/75 (41%), Positives = 43/75 (57%), Gaps = 3/75 (4%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPH-TVEEKNSENPPPGYPGLETILPLL 64 A+V P L ED+ L + IID FATDHAPH T E++ E PG GL+T LP Sbjct: 275 ARVNPPLRKKEDRLALIEGVKRGIIDCFATDHAPHQTFEKELVEFAMPGIIGLQTALPSA 334 Query: 63 LNAVHQGRLTIEDLL 19 L +G ++++ L+ Sbjct: 335 LELYRKGIISLKKLI 349 Score = 47.6 bits (108), Expect = 4e-04 Identities = 24/60 (40%), Positives = 35/60 (58%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE + A ++A VHI HV+ K + II+ KE+GVK+TCEV P+HL ++ Sbjct: 209 AEEIQIARDGILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGVKITCEVNPNHLLFTEREV 268 Score = 46.4 bits (105), Expect = 9e-04 Identities = 25/61 (40%), Positives = 33/61 (54%), Gaps = 2/61 (3%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFD 653 ++ PGFID+HVH+R+PG K D+ V T I MPNTNP I + T + Sbjct: 51 LIVCPGFIDIHVHLRDPGQTYKE---DIESGSRCAVAGGFTTIVCMPNTNPPIDNTTVVN 107 Query: 652 Y 650 Y Sbjct: 108 Y 108 >UniRef50_A6TVS5 Cluster: Dihydroorotase; n=8; Clostridiales|Rep: Dihydroorotase - Alkaliphilus metalliredigens QYMF Length = 429 Score = 51.2 bits (117), Expect = 3e-05 Identities = 24/62 (38%), Positives = 35/62 (56%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE A I++A +H+CHV+ K + + + AK+RG VT EVCPHH L + + Sbjct: 209 AEEVIIARDIILARNTGVKLHLCHVSTKGGVELTREAKQRGENVTAEVCPHHFALTEDIV 268 Query: 254 TK 249 K Sbjct: 269 EK 270 Score = 41.9 bits (94), Expect = 0.019 Identities = 23/50 (46%), Positives = 29/50 (58%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVD 668 +PG IDVHVH+REPG K + + + T IC MPNT P +VD Sbjct: 53 VPGLIDVHVHLREPGFEHKETI-ETGSKSAAMGGFTTICCMPNTQP-VVD 100 Score = 41.1 bits (92), Expect = 0.034 Identities = 25/60 (41%), Positives = 34/60 (56%), Gaps = 4/60 (6%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67 +K+ P L + ED + + + I+V ATDHAPH +EKN E P G GLET L + Sbjct: 275 SKMNPPLRTGEDVDAIKQGLVDGTIEVIATDHAPHHADEKNQEFHQAPFGIVGLETALSI 334 >UniRef50_A7D6W5 Cluster: Amidohydrolase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: Amidohydrolase - Halorubrum lacusprofundi ATCC 49239 Length = 463 Score = 51.2 bits (117), Expect = 3e-05 Identities = 28/76 (36%), Positives = 45/76 (59%), Gaps = 6/76 (7%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPP---PGYPGLETIL 73 R V P + S EDQ LW+ ++ I TDH + ++K E+ P PG+P T+L Sbjct: 293 RHNVNPPVRSKEDQETLWKRVADGTISCIGTDHCANLRDDKVGEDVPDSLPGFPSTATML 352 Query: 72 PLLLN-AVHQGRLTIE 28 PL+L+ V++GR+++E Sbjct: 353 PLILSEGVNEGRISLE 368 >UniRef50_A5DGE8 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 378 Score = 50.8 bits (116), Expect = 4e-05 Identities = 23/62 (37%), Positives = 35/62 (56%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 E E T I+M+ +D PV HV+ E I I+ A+ RG+ V E CP +L L + D+ Sbjct: 103 EGEATNRAIVMSEAMDSPVLFVHVSAPEAIRSIREARSRGLSVFAETCPQYLLLKAEDLK 162 Query: 251 KL 246 ++ Sbjct: 163 RI 164 >UniRef50_Q6AF87 Cluster: Dihydroorotase; n=9; Actinobacteria (class)|Rep: Dihydroorotase - Leifsonia xyli subsp. xyli Length = 438 Score = 50.8 bits (116), Expect = 4e-05 Identities = 23/55 (41%), Positives = 33/55 (60%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 AE A +L+A + +H+CHV+ + +I+ AK RG+ VT EV PHHL L Sbjct: 209 AEESIIARDVLLAEHVGSRLHVCHVSTAGSVDVIRWAKARGIDVTAEVTPHHLLL 263 Score = 39.1 bits (87), Expect = 0.14 Identities = 27/66 (40%), Positives = 36/66 (54%), Gaps = 4/66 (6%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPP--GYPGLETILP 70 R KV P L ED L ++ ID+ ATDHAPH VE K+ E G GLE+ L Sbjct: 274 RYKVNPPLRRSEDVEALRAGLADGTIDIVATDHAPHPVEAKDCEWDAAAFGMVGLESALS 333 Query: 69 LLLNAV 52 ++ ++V Sbjct: 334 VVQSSV 339 >UniRef50_Q1M4X9 Cluster: Putative D-hydantoinase; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative D-hydantoinase - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 477 Score = 50.4 bits (115), Expect = 6e-05 Identities = 22/59 (37%), Positives = 36/59 (61%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +RE T I ++ L++ P+ + HVA + I+ AK RG+ + E CP +LFL++ DI Sbjct: 222 DREATFRAISLSELIETPILVSHVAAGGAVEEIRRAKARGLPIYAETCPQYLFLSAEDI 280 Score = 35.1 bits (77), Expect = 2.2 Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 11/82 (13%) Frame = -1 Query: 240 GRAKVC-PVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSENP-------PPGYP 91 G VC P +Q +W I ++VF++DH+P +K + P P G P Sbjct: 287 GSKCVCTPPPRDKSNQPAIWAGILDGTLEVFSSDHSPWHYADKIAGGPGTPFHRIPNGIP 346 Query: 90 GLETILPLLLNA-VHQGRLTIE 28 G+ET L LL +A V+ G ++++ Sbjct: 347 GIETRLALLFSAGVNGGLISLQ 368 >UniRef50_Q18ZN3 Cluster: Dihydroorotase; n=3; Clostridiales|Rep: Dihydroorotase - Desulfitobacterium hafniense (strain DCB-2) Length = 434 Score = 50.4 bits (115), Expect = 6e-05 Identities = 23/66 (34%), Positives = 35/66 (53%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +E A IL+A +H+ H++ KE + +I+ K+RGV VT EV PHHL + Sbjct: 217 SESVMVARDILLAEESGGKLHLAHISAKESVALIREGKKRGVDVTAEVNPHHLLFTDEAV 276 Query: 254 TKLEKG 237 + G Sbjct: 277 ARTPYG 282 Score = 44.0 bits (99), Expect = 0.005 Identities = 32/76 (42%), Positives = 40/76 (52%), Gaps = 5/76 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 64 KV P L ED+ L + +D+ ATDHAPHT EEK + + P G GLET L + Sbjct: 286 KVNPPLRREEDRQALIEGLLDGTLDMLATDHAPHTWEEKTNPFDQAPFGISGLETALAAV 345 Query: 63 -LNAVHQGRLTIEDLL 19 V G L IE L+ Sbjct: 346 WQELVTTGILPIELLI 361 Score = 38.3 bits (85), Expect = 0.24 Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 2/57 (3%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLV--VLTMICAMPNTNPSIVDRTAFDY 650 PG IDVH H+REPG K D+ V T I AMPNT P + + +Y Sbjct: 62 PGLIDVHTHLREPGREDKE---DIASGSRAAVRGGFTTILAMPNTTPILDQKALVEY 115 >UniRef50_Q9RVC3 Cluster: Dihydroorotase; n=5; Deinococci|Rep: Dihydroorotase - Deinococcus radiodurans Length = 416 Score = 50.4 bits (115), Expect = 6e-05 Identities = 22/60 (36%), Positives = 35/60 (58%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 A + A + + +L +H+ H++ E+ I++ AK RG+ VTCEVCPHHL L + Sbjct: 202 AAAARVARDMEIVALTGARLHVQHLSTARELDIVRDAKRRGLPVTCEVCPHHLDLTDESL 261 Score = 35.9 bits (79), Expect = 1.3 Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 4/75 (5%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64 KV P L + D L + +D ATDHAPHT EK + + P G +E P++ Sbjct: 269 KVAPPLRTRADADYLLEGLLDGSVDCIATDHAPHTRAEKERDLLDAPSGIAYIEIAFPIM 328 Query: 63 LNAVHQGRLTIEDLL 19 + RL +E L+ Sbjct: 329 WTRFGE-RLGLEKLI 342 >UniRef50_Q3AEA1 Cluster: Allantoinase; n=3; Clostridiales|Rep: Allantoinase - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 471 Score = 50.0 bits (114), Expect = 7e-05 Identities = 28/81 (34%), Positives = 48/81 (59%), Gaps = 9/81 (11%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVE-EKNSENPP-----PGYPGLET 79 AK+ P L + D LW ++ +D ATDHAP+ + EK +E PG PG+ET Sbjct: 288 AKIAPPLRTTRDNEMLWEQLADGRVDFIATDHAPYEIATEKEAEGMDIWTAFPGIPGVET 347 Query: 78 ILPLLLN-AVHQGRLTIEDLL 19 ++P++++ ++GRL++ L+ Sbjct: 348 MVPIIISEGYNKGRLSLSRLV 368 Score = 40.7 bits (91), Expect = 0.045 Identities = 20/57 (35%), Positives = 31/57 (54%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264 AE+ I A +HI H++ +++ AK+RG+ VT E CPH+L LN+ Sbjct: 221 AEKVAIQMAISFAEETGARLHIVHMSTGIGGVLVGEAKKRGLDVTAETCPHYLVLNA 277 >UniRef50_A6P0Z6 Cluster: Dihydroorotase; n=1; Bacteroides capillosus ATCC 29799|Rep: Dihydroorotase - Bacteroides capillosus ATCC 29799 Length = 427 Score = 50.0 bits (114), Expect = 7e-05 Identities = 22/66 (33%), Positives = 37/66 (56%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE + ++A VHICH++ + + I++ K +GV++TCE CP + L ++I Sbjct: 209 AEELQVMRDAMLAEETGAAVHICHISTAKSVAIVRRYKRKGVQITCETCPQYFSLTEDEI 268 Query: 254 TKLEKG 237 L KG Sbjct: 269 --LTKG 272 Score = 47.2 bits (107), Expect = 5e-04 Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 3/53 (5%) Frame = -1 Query: 168 IDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLNAV-HQGRLTIEDLL 19 ID ATDHAPH+ EEK P G GLET L + L A+ H G + + D+L Sbjct: 299 IDAIATDHAPHSAEEKGRPLTEAPSGMVGLETALGVTLTALYHTGEMGLSDIL 351 >UniRef50_A3H6L5 Cluster: Amidohydrolase; n=1; Caldivirga maquilingensis IC-167|Rep: Amidohydrolase - Caldivirga maquilingensis IC-167 Length = 407 Score = 50.0 bits (114), Expect = 7e-05 Identities = 30/68 (44%), Positives = 40/68 (58%), Gaps = 5/68 (7%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK---NSENPPPGYPGLETILPL 67 KV P L S + EL R + I + A+DHAPHT+ EK N ++ PG+PGLET L Sbjct: 243 KVNPPLRSKSIRFELLRRLIDGSISIIASDHAPHTISEKFHNNYDDTSPGFPGLETTGLL 302 Query: 66 LLNAVHQG 43 LL+ +G Sbjct: 303 LLDLWRRG 310 >UniRef50_Q8R9R6 Cluster: Dihydroorotase; n=5; Clostridia|Rep: Dihydroorotase - Thermoanaerobacter tengcongensis Length = 431 Score = 50.0 bits (114), Expect = 7e-05 Identities = 23/53 (43%), Positives = 31/53 (58%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 276 AE A I++A +HI HV+ K + +I+ AKE GV +T EV PHHL Sbjct: 208 AEEVMLARNIILAKATGAKLHIAHVSTKGSVELIRRAKEEGVSITAEVTPHHL 260 Score = 41.9 bits (94), Expect = 0.019 Identities = 21/62 (33%), Positives = 30/62 (48%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638 LPGF+D+H H+R+PG K + T + MPNTNP I +Y + Sbjct: 52 LPGFVDMHTHLRQPGFEEKETI-RTGTESAAAGGFTTVACMPNTNPPIDSEVVVEYVKAV 110 Query: 637 AR 632 A+ Sbjct: 111 AQ 112 Score = 38.7 bits (86), Expect = 0.18 Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 5/76 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKN--SENPPPGYPGLETILPLL 64 KV P L + ED L + ID ATDHAPHT ++K + P G GLET ++ Sbjct: 275 KVFPPLRTREDVEALIEGLKDGTIDAIATDHAPHTKDDKKVPYDMAPFGISGLETAFSVI 334 Query: 63 LN-AVHQGRLTIEDLL 19 + G +T++ L+ Sbjct: 335 NTFLIQTGIITMKALV 350 >UniRef50_A7CWA7 Cluster: Dihydroorotase, multifunctional complex type; n=1; Opitutaceae bacterium TAV2|Rep: Dihydroorotase, multifunctional complex type - Opitutaceae bacterium TAV2 Length = 433 Score = 49.6 bits (113), Expect = 1e-04 Identities = 31/83 (37%), Positives = 46/83 (55%), Gaps = 8/83 (9%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 70 R K+ P L + +D+ + + +D+ ATDHAPHT +EK+ E P G GLET LP Sbjct: 276 RFKMNPPLRTEDDRLAIIEGLRDGTLDIIATDHAPHTDDEKDKEFDYAPNGIIGLETSLP 335 Query: 69 LLLNAVHQGR----LTIEDLLCR 13 + L +H+ T+ DL+ R Sbjct: 336 ISLEILHRQNKFKLATVIDLMTR 358 Score = 39.9 bits (89), Expect = 0.078 Identities = 17/46 (36%), Positives = 27/46 (58%) Frame = -2 Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 +++A+ +H+ H++ + II+ AK RGV VT E PHH L Sbjct: 220 VILATYTGARIHMQHISSHNAVDIIRRAKTRGVPVTAEGTPHHFAL 265 Score = 35.9 bits (79), Expect = 1.3 Identities = 18/49 (36%), Positives = 25/49 (51%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP 680 +V PG +D+HVH REPG K + + T + MPNT+P Sbjct: 51 LVAAPGLVDIHVHFREPGQTHKETI-ETGSRAAAAGGFTSVVCMPNTSP 98 >UniRef50_Q97LN7 Cluster: Dihydroorotase; n=4; Clostridiales|Rep: Dihydroorotase - Clostridium acetobutylicum Length = 424 Score = 49.6 bits (113), Expect = 1e-04 Identities = 33/80 (41%), Positives = 43/80 (53%), Gaps = 5/80 (6%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67 AKV P L +D+ + + I V ATDHAPHT +EK E P G GLET L L Sbjct: 274 AKVNPPLRREDDRKAIVAALKDDTIQVIATDHAPHTKDEKAREFKEAPSGMIGLETALSL 333 Query: 66 -LLNAVHQGRLTIEDLLCRI 10 + N V G LT D++ ++ Sbjct: 334 AVTNLVKTGDLTYRDMISKL 353 Score = 34.7 bits (76), Expect = 2.9 Identities = 20/66 (30%), Positives = 28/66 (42%) Frame = -2 Query: 452 MPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 273 M AE TA +A +I H++ K + IIK AKE G + E P H Sbjct: 202 MGALEEAETVLTARDAALAVSSGAKTNIQHISSKISLGIIKLAKEMGANIIAEATPQHFS 261 Query: 272 LNSNDI 255 + +I Sbjct: 262 ITEEEI 267 >UniRef50_A4GK51 Cluster: Dihydroorotase; n=1; uncultured marine bacterium HF130_81H07|Rep: Dihydroorotase - uncultured marine bacterium HF130_81H07 Length = 444 Score = 49.2 bits (112), Expect = 1e-04 Identities = 34/104 (32%), Positives = 48/104 (46%), Gaps = 2/104 (1%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*-DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638 PG ID VH R+PG KG + L H V T MPN NP+ + L Sbjct: 54 PGIIDDQVHFRDPGLTEKGDIRSESLAAVHGGVTSTF--DMPNVNPNTTTIELMSARNKL 111 Query: 637 ARVSARCDYALYVGASSTNYDTICELAP-QAAALKMYLNETFTT 509 + +YA Y GA+ TN + I +L P + LK+++ + T Sbjct: 112 GAEKSWTNYAYYFGATETNIEEIKKLDPKEICGLKVFMGTSTGT 155 Score = 42.7 bits (96), Expect = 0.011 Identities = 27/101 (26%), Positives = 44/101 (43%) Frame = -2 Query: 548 CSSKDVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHI 369 C + +K N LE+ I F K +C + K VI +A +H+ Sbjct: 179 CEDNETMKNNLERVKLENAEI-DASFHPIIKD-DICCYRSSSK---VINLAKKYSSDLHV 233 Query: 368 CHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246 H+ ++EI + + +TCEVC HHL+ + D +L Sbjct: 234 LHLTTEKEIELFTNDPVKDKNITCEVCVHHLWFDERDYKEL 274 Score = 37.9 bits (84), Expect = 0.31 Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 9/82 (10%) Frame = -1 Query: 219 VLCSPEDQAELWRNI-------SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67 ++C+P + E RN ID ATDHAPH EEK G P +E + Sbjct: 278 IVCNPAIKKESDRNALRKALKDGFIDYVATDHAPHVYEEKLRPYLQASAGIPLIEHSFHI 337 Query: 66 LLNAVHQGRLTIEDLLCRIRHE 1 ++ QG +IE+++ + H+ Sbjct: 338 MMELQKQGVYSIEEVVAFMSHK 359 >UniRef50_A0RQX7 Cluster: Dihydroorotase; n=4; Campylobacter|Rep: Dihydroorotase - Campylobacter fetus subsp. fetus (strain 82-40) Length = 426 Score = 49.2 bits (112), Expect = 1e-04 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 5/76 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRN---ISIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPL 67 K+ P L + D E RN +IDV TDHAPH +EK + P G GL+T++PL Sbjct: 273 KMSPPLRTNND-VEAMRNGLKNGLIDVICTDHAPHHTDEKFLEFDKAPFGILGLQTLVPL 331 Query: 66 LLNAVHQGRLTIEDLL 19 LN V +G + E ++ Sbjct: 332 TLNLVREGVIDYEQMV 347 Score = 48.0 bits (109), Expect = 3e-04 Identities = 18/51 (35%), Positives = 31/51 (60%) Frame = -2 Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +L+A L +H+ HV+ + +I+ AK GV +TCEV PHH + +++ Sbjct: 215 MLLAKLTGGHIHVAHVSSAYSLKLIEQAKNEGVNITCEVTPHHFTFSEDEL 265 Score = 38.3 bits (85), Expect = 0.24 Identities = 21/52 (40%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Frame = -3 Query: 829 NIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNP 680 N + +PG ID+HVH R+PG K D++ V +T C M NTNP Sbjct: 46 NKLVMPGLIDMHVHFRDPGLEYKD---DIITGSMSAVAGGVTTACPMANTNP 94 >UniRef50_UPI00015BB20A Cluster: dihydroorotase; n=1; Ignicoccus hospitalis KIN4/I|Rep: dihydroorotase - Ignicoccus hospitalis KIN4/I Length = 383 Score = 48.8 bits (111), Expect = 2e-04 Identities = 23/50 (46%), Positives = 32/50 (64%), Gaps = 2/50 (4%) Frame = -1 Query: 162 VFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLL 19 + TDHAPH V EK + PPG+PGLET LPLLL +G +++ ++ Sbjct: 254 MMVTDHAPHAVWEKELPFYDCPPGFPGLETALPLLLTLYKRGIISLNKVV 303 >UniRef50_Q8F061 Cluster: Dihydroorotase; n=5; Bacteria|Rep: Dihydroorotase - Leptospira interrogans Length = 424 Score = 48.8 bits (111), Expect = 2e-04 Identities = 29/87 (33%), Positives = 43/87 (49%) Frame = -2 Query: 512 NFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILII 333 +F ED I +KH + AE T + + + +CH + E + I Sbjct: 181 SFHCEDPEILEKHQNETFHEDRRPAEAETTATDFALYLIEKYNLRGKLCHYSTGEGLNKI 240 Query: 332 KAAKERGVKVTCEVCPHHLFLNSNDIT 252 K AK++GVKVTCEV P HLF + + +T Sbjct: 241 KFAKQKGVKVTCEVTPTHLFFDRSMLT 267 Score = 35.1 bits (77), Expect = 2.2 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%) Frame = -1 Query: 222 PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK 121 P L S ED+ + + ID ATDHAPH++EEK Sbjct: 278 PPLRSKEDRERMLEGVKQGWIDYLATDHAPHSIEEK 313 >UniRef50_Q83HU2 Cluster: Dihydroorotase; n=2; Tropheryma whipplei|Rep: Dihydroorotase - Tropheryma whipplei (strain TW08/27) (Whipple's bacillus) Length = 428 Score = 48.8 bits (111), Expect = 2e-04 Identities = 23/53 (43%), Positives = 31/53 (58%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 276 AE A IL+A + +H+CHV+ +E + I K GV+VT EV PHHL Sbjct: 215 AESTIVARDILLARAANARLHVCHVSSQESVYAIAWGKSLGVQVTAEVTPHHL 267 Score = 37.9 bits (84), Expect = 0.31 Identities = 29/75 (38%), Positives = 37/75 (49%), Gaps = 4/75 (5%) Frame = -1 Query: 246 GKGRAKVCPVLCSPEDQAELWRNI---SIIDVFATDHAPHTVEEKNSENPPPGYPGLETI 76 G R KV P L S E E R+ +IDV ATDHAPH + + P G GLE Sbjct: 277 GDTRFKVNPPLRSKES-VECLRDALIRGVIDVVATDHAPHRNKSPFWHSAPNGMTGLEFS 335 Query: 75 LPLLLNA-VHQGRLT 34 + ++ V+ G LT Sbjct: 336 VSVIQKIFVNSGHLT 350 >UniRef50_Q765R4 Cluster: Allantoinase; n=1; Klebsiella pneumoniae|Rep: Allantoinase - Klebsiella pneumoniae Length = 336 Score = 48.8 bits (111), Expect = 2e-04 Identities = 22/68 (32%), Positives = 38/68 (55%) Frame = -2 Query: 449 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 PV T E E V+ +A + +H+CHV+ E + + A++ G VTCE CPH+ L Sbjct: 229 PVFT--EVEAIRRVLYLAKVAGCRLHVCHVSSPEGVAEVTRARQEGQDVTCESCPHYFVL 286 Query: 269 NSNDITKL 246 +++ ++ Sbjct: 287 DTDQFAEI 294 Score = 34.3 bits (75), Expect = 3.9 Identities = 25/89 (28%), Positives = 35/89 (39%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 ++ PG +D H H+ EPG + + TMI N P+ VDR + Sbjct: 62 LIVSPGMVDAHTHISEPGRTHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRQTIELK 121 Query: 646 STLARVSARCDYALYVGASSTNYDTICEL 560 A+ D A G S N D + EL Sbjct: 122 FDAAKGKLTIDAAQLGGLVSYNLDRLHEL 150 >UniRef50_Q18S75 Cluster: Amidohydrolase; n=2; Desulfitobacterium hafniense|Rep: Amidohydrolase - Desulfitobacterium hafniense (strain DCB-2) Length = 452 Score = 48.8 bits (111), Expect = 2e-04 Identities = 29/84 (34%), Positives = 38/84 (45%) Frame = -2 Query: 500 EDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAK 321 +D WQ S P AE T +I +A + VHICHV+ II+ A+ Sbjct: 199 KDTNDWQDFLDSRP------VIAELIATQNIIDLAKEVGAKVHICHVSHPRVAEIIRQAQ 252 Query: 320 ERGVKVTCEVCPHHLFLNSNDITK 249 GV VT E C H+L D+ K Sbjct: 253 NEGVDVTAETCGHYLTFTDQDVVK 276 >UniRef50_A6R6Y6 Cluster: Allantoinase; n=1; Ajellomyces capsulatus NAm1|Rep: Allantoinase - Ajellomyces capsulatus NAm1 Length = 592 Score = 48.8 bits (111), Expect = 2e-04 Identities = 22/60 (36%), Positives = 37/60 (61%), Gaps = 1/60 (1%) Frame = -2 Query: 431 EREKTAAVILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 E +A++ +A L P+HI H++ E I ++KAA+ RGV +T E C H+L L + ++ Sbjct: 254 ETTAISAILSLAPLAPNLPLHIVHLSAMEAIPLLKAARRRGVNITAETCFHYLSLTAEEV 313 >UniRef50_Q97QN4 Cluster: Dihydroorotase; n=47; Firmicutes|Rep: Dihydroorotase - Streptococcus pneumoniae Length = 422 Score = 48.8 bits (111), Expect = 2e-04 Identities = 33/78 (42%), Positives = 43/78 (55%), Gaps = 6/78 (7%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSEN---PPPGYPGLETILP 70 AK+ P L D+ + + +I V ATDHAPH V+EKN E+ P G GLET L Sbjct: 273 AKMNPPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLS 332 Query: 69 LLLN-AVHQGRLTIEDLL 19 L L V G L++ +LL Sbjct: 333 LSLTYLVEAGELSLMELL 350 Score = 37.9 bits (84), Expect = 0.31 Identities = 17/52 (32%), Positives = 30/52 (57%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 279 AE A +++A VHI H++++E + +++ A+ G +VT EV P H Sbjct: 207 AEYAMMARDVMIAYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQH 258 Score = 33.1 bits (72), Expect = 8.9 Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVD 668 +V PG +D+HVH REPG K D+ T + M NT+P+I D Sbjct: 49 LVVAPGLVDIHVHFREPGQTHKE---DIHTGALAAAAGGFTTVVMMANTSPTISD 100 >UniRef50_Q8TSA6 Cluster: Dihydroorotase; n=4; Methanosarcinaceae|Rep: Dihydroorotase - Methanosarcina acetivorans Length = 467 Score = 48.8 bits (111), Expect = 2e-04 Identities = 23/56 (41%), Positives = 35/56 (62%), Gaps = 2/56 (3%) Frame = -1 Query: 180 NISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLL 19 N ID+ A+DHAPH EK+ + P G PG+ET++PL+L AV + L + ++ Sbjct: 303 NDGTIDMVASDHAPHLESEKDLDIRAAPSGVPGVETLMPLMLAAVRKNILPLSQMI 358 Score = 43.6 bits (98), Expect = 0.006 Identities = 30/86 (34%), Positives = 42/86 (48%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638 LP IDVHVH REPG +K + + T+I PNT P DR +F+ L Sbjct: 53 LPAGIDVHVHFREPGMTLKENWYTGSCAAAAGGIATVI-DQPNTIPPTTDRRSFEQKLKL 111 Query: 637 ARVSARCDYALYVGASSTNYDTICEL 560 AR + D+ + G + N + + EL Sbjct: 112 ARKKSIVDFGINGGVTG-NIEKLREL 136 Score = 39.1 bits (87), Expect = 0.14 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 6/68 (8%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKA----AKERGVK--VTCEVCPHHLFL 270 E + + + S L H CH++ E + +I+ AK K TCEV PHHLFL Sbjct: 212 EASAVQSALELISRLQVRAHFCHLSTLEAVGMIRKEKYLAKRENKKPLFTCEVTPHHLFL 271 Query: 269 NSNDITKL 246 ++ D +L Sbjct: 272 SAKDWERL 279 >UniRef50_Q64RK7 Cluster: Dihydroorotase; n=6; Bacteroidales|Rep: Dihydroorotase - Bacteroides fragilis Length = 459 Score = 48.4 bits (110), Expect = 2e-04 Identities = 30/103 (29%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644 +PG ID HVH R+PG K D+ + +T I MPNTNP A + Sbjct: 55 IPGVIDDHVHFRDPGLTHKA---DISTESRAAAAGGVTSIMDMPNTNPQTTTLDALNAKF 111 Query: 643 TLARVSARCDYALYVGASSTNYDTICEL-APQAAALKMYLNET 518 L +Y+ Y GA++ NY +L + +K+++ + Sbjct: 112 DLLAEKCSVNYSCYFGATNNNYTEFDKLDKNRVCGIKLFMGSS 154 Score = 43.6 bits (98), Expect = 0.006 Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 2/61 (3%) Frame = -1 Query: 180 NISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRIR 7 N ++IDV ATDHAPH ++EK G P ++ L +L V++G TIE ++ ++ Sbjct: 314 NSNLIDVIATDHAPHLLKEKEGGPLKAMSGMPMIQFSLVSMLELVNEGIFTIEKVVEKMC 373 Query: 6 H 4 H Sbjct: 374 H 374 Score = 35.1 bits (77), Expect = 2.2 Identities = 25/113 (22%), Positives = 52/113 (46%), Gaps = 9/113 (7%) Frame = -2 Query: 557 SASCSSKDVLK*NFYNFLLEDMTIW-QKHFQSWPKKMPVCTHAEREKTAA-------VIL 402 +A C + + +K N ++ E + + +++ + +P+ HA+ AA + Sbjct: 178 AAHCENHETIKKNTEKYVKEYIEKYPHQYYHVHHETLPMGYHAKIRSIAACYESSELAVR 237 Query: 401 MASLLDRPVHICHVARKEEI-LIIKAAKERGVKVTCEVCPHHLFLNSNDITKL 246 +A + D +HI H++ E+ L ++T E C HL +S+D +L Sbjct: 238 LARIADARLHILHISTARELSLFDNDIPLEEKRITAEACVSHLLFDSSDYPEL 290 >UniRef50_Q1M4Y4 Cluster: Putative dihydroorotase; n=1; Rhizobium leguminosarum bv. viciae 3841|Rep: Putative dihydroorotase - Rhizobium leguminosarum bv. viciae (strain 3841) Length = 444 Score = 48.4 bits (110), Expect = 2e-04 Identities = 38/128 (29%), Positives = 62/128 (48%), Gaps = 7/128 (5%) Frame = -1 Query: 381 ACTHLSRSTKRRNINYQSRKRKRC*SYL*SLPTSLIFE***HYKIGKGRAKVCPVLCSPE 202 A H+ + R + R R + + P +L F Y+ R K P + Sbjct: 227 ARVHVRQINSRLGVETWRRLRSMADVTVETTPQNLFFTSD-DYESEGARLKGSPPFRGRD 285 Query: 201 DQAELWRNIS--IIDVFATDHAPHTVEEKNS-----ENPPPGYPGLETILPLLLNAVHQG 43 D A L R +S +I + ATDHAPH+ EK++ + P G PGL+T+L ++L+ V + Sbjct: 286 DVAALRRAVSEGLITIMATDHAPHSPAEKSAVYGSFADIPGGMPGLQTLLSVMLDLVAEK 345 Query: 42 RLTIEDLL 19 + + DL+ Sbjct: 346 VIGLTDLV 353 Score = 35.5 bits (78), Expect = 1.7 Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 2/95 (2%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP--SIVDRTAFDYAS 644 LPG +D HVH+REPG K F + L +T I MP +P + + + AS Sbjct: 53 LPGLVDAHVHLREPGMTQKEDF-ESGTHAAALGGVTTILDMPTDDPWTATAQQLSDKMAS 111 Query: 643 TLARVSARCDYALYVGASSTNYDTICELAPQAAAL 539 + + V S + + + L+P + L Sbjct: 112 AAGGIHVDVGFQAVVSKSYDSLEDLLALSPVSLEL 146 >UniRef50_A5ZPT0 Cluster: Dihydroorotase; n=1; Ruminococcus obeum ATCC 29174|Rep: Dihydroorotase - Ruminococcus obeum ATCC 29174 Length = 430 Score = 48.4 bits (110), Expect = 2e-04 Identities = 31/77 (40%), Positives = 45/77 (58%), Gaps = 5/77 (6%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPL 67 AK+ P L + +D+ E+ + ID+ ATDHAPH+ EEK P G GLET L L Sbjct: 273 AKMNPPLRTEKDRQEIIHGLKDGTIDLIATDHAPHSEEEKAKPLTEAPSGITGLETSLGL 332 Query: 66 -LLNAVHQGRLTIEDLL 19 + + V +G L++ +LL Sbjct: 333 GITSLVKEGYLSLMELL 349 >UniRef50_Q44184 Cluster: D-hydantoinase; n=5; Proteobacteria|Rep: D-hydantoinase - Agrobacterium tumefaciens Length = 457 Score = 48.4 bits (110), Expect = 2e-04 Identities = 22/70 (31%), Positives = 38/70 (54%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 E E TA + +A +++ P++I H+ +E + AK RGV E C +L+L +D+ Sbjct: 215 EAEATARALALAEIVNAPIYIVHLTCEESFDELMRAKARGVHALAETCTQYLYLTKDDLE 274 Query: 251 KLEKGEQKYV 222 + + KYV Sbjct: 275 RPDFEGAKYV 284 >UniRef50_Q1Q402 Cluster: Similar to dihydroorotase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to dihydroorotase - Candidatus Kuenenia stuttgartiensis Length = 444 Score = 48.0 bits (109), Expect = 3e-04 Identities = 20/40 (50%), Positives = 30/40 (75%), Gaps = 1/40 (2%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGV-KVTCEVCPHHLFLNSN 261 +HI H++ K+ + I+ AKERG+ K TCEV PHHL L+++ Sbjct: 246 LHISHISLKDTLAAIQQAKERGIGKFTCEVTPHHLLLDNS 285 Score = 46.8 bits (106), Expect = 7e-04 Identities = 25/55 (45%), Positives = 36/55 (65%), Gaps = 1/55 (1%) Frame = -1 Query: 171 IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLL-NAVHQGRLTIEDLLCRI 10 IIDV ATDHAPHT + + + G+ GLET L +LL VH G +T ++L+ ++ Sbjct: 317 IIDVIATDHAPHT--DDDLKKGATGFVGLETALGVLLTKLVHTGIITFKELIIKM 369 Score = 33.5 bits (73), Expect = 6.8 Identities = 20/48 (41%), Positives = 23/48 (47%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSI 674 +PG I+ HVH REPG K T+IC PNTNP I Sbjct: 73 IPGLIECHVHFREPGLEYKEDIRTGSRAAAKGGYTTVICE-PNTNPPI 119 >UniRef50_P77671 Cluster: Allantoinase; n=25; Bacteria|Rep: Allantoinase - Escherichia coli (strain K12) Length = 453 Score = 47.6 bits (108), Expect = 4e-04 Identities = 22/68 (32%), Positives = 38/68 (55%) Frame = -2 Query: 449 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 PV T E E V+ +A + +H+CHV+ E + + A++ G VTCE CPH+ L Sbjct: 216 PVFT--EVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVL 273 Query: 269 NSNDITKL 246 +++ ++ Sbjct: 274 DTDQFEEI 281 Score = 35.9 bits (79), Expect = 1.3 Identities = 26/89 (29%), Positives = 37/89 (41%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 +V PG +D H H+ EPG + + + TMI N P+ VDR + + Sbjct: 49 LVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELK 108 Query: 646 STLARVSARCDYALYVGASSTNYDTICEL 560 A+ D A G S N D + EL Sbjct: 109 FDAAKGKLTIDAAQLGGLVSYNIDRLHEL 137 >UniRef50_A5NXH5 Cluster: Allantoinase; n=2; Proteobacteria|Rep: Allantoinase - Methylobacterium sp. 4-46 Length = 495 Score = 47.2 bits (107), Expect = 5e-04 Identities = 20/55 (36%), Positives = 38/55 (69%), Gaps = 5/55 (9%) Frame = -1 Query: 171 IIDVFATDHAPHTVEE-----KNSENPPPGYPGLETILPLLLNAVHQGRLTIEDL 22 + D+ +HAPH+VE+ +++ + P G G + +PL+LNAV++GR+T++D+ Sbjct: 314 VADMLVGEHAPHSVEDVEPGWEDNFSVPLGITGAQEFVPLMLNAVNEGRMTLQDI 368 >UniRef50_A0L3T8 Cluster: Dihydroorotase, multifunctional complex type; n=2; unclassified Proteobacteria|Rep: Dihydroorotase, multifunctional complex type - Magnetococcus sp. (strain MC-1) Length = 428 Score = 46.8 bits (106), Expect = 7e-04 Identities = 19/64 (29%), Positives = 32/64 (50%) Frame = -2 Query: 446 VCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267 +C AE I + L H+ H++ + + A+E+G++V+CE PHHL LN Sbjct: 209 ICNAAEDILVERDIRLVELTGGRYHVAHISSAGAVASVAKAREKGLRVSCEAAPHHLVLN 268 Query: 266 SNDI 255 + Sbjct: 269 DTHV 272 Score = 43.2 bits (97), Expect = 0.008 Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 4/79 (5%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67 AK+ P L + D + ++ +I V ATDHAPH + K G GLET+LP+ Sbjct: 279 AKMAPPLRNQRDVNAIQEALARGVISVIATDHAPHEEDSKRVPFCQAANGVVGLETLLPI 338 Query: 66 LLNAVHQGRLTIEDLLCRI 10 L V G L + L I Sbjct: 339 TLELVEAGVLPLAKALAAI 357 Score = 39.1 bits (87), Expect = 0.14 Identities = 23/67 (34%), Positives = 33/67 (49%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 ++ PG +D+HVH+REPG K + +T + AMPNT P D + Y Sbjct: 54 LIAAPGLVDMHVHLREPGYEYKETIAG-GTRAAAAGGVTSVAAMPNTKPVNDDPSVTGYM 112 Query: 646 STLARVS 626 ARV+ Sbjct: 113 LDKARVA 119 >UniRef50_P81006 Cluster: Non-ATP-dependent L-selective hydantoinase; n=3; Arthrobacter|Rep: Non-ATP-dependent L-selective hydantoinase - Arthrobacter aurescens Length = 458 Score = 46.8 bits (106), Expect = 7e-04 Identities = 30/79 (37%), Positives = 42/79 (53%), Gaps = 8/79 (10%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE-----NPPPGYPGLETIL 73 KV P + S E LW + +ID +DH H VE+K G GLET L Sbjct: 283 KVAPPVRSAEMNIRLWEQLENGLIDTLGSDHGGHPVEDKEPGWKDVWKAGNGALGLETSL 342 Query: 72 PLLL-NAVHQGRLTIEDLL 19 P++L N V++GRL++E L+ Sbjct: 343 PMMLTNGVNKGRLSLERLV 361 Score = 34.3 bits (75), Expect = 3.9 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 1/84 (1%) Frame = -3 Query: 817 LPGFIDVHVHVREPG-ANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYAST 641 +PG +D HVH+ + N GRF +L + + +T I MP T P AF Sbjct: 53 MPGVVDEHVHIIDMDLKNRYGRF-ELDSESAAVGGITTIIEMPITFPPTTTLDAFLEKKK 111 Query: 640 LARVSARCDYALYVGASSTNYDTI 569 A + D+ALY G N I Sbjct: 112 QAGQRLKVDFALYGGGVPGNLPEI 135 >UniRef50_O69809 Cluster: D-hydantoinase; n=4; Bacteria|Rep: D-hydantoinase - Streptomyces coelicolor Length = 467 Score = 46.8 bits (106), Expect = 7e-04 Identities = 21/70 (30%), Positives = 40/70 (57%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 E E T I +A + P+++ HV+ E + + A++ G+ V E CP +LFL+++++ Sbjct: 223 EAEATHRAIRLAQVAGAPLYVVHVSATEAVAELTRARDEGLPVFGETCPQYLFLSTDNLA 282 Query: 251 KLEKGEQKYV 222 + + KYV Sbjct: 283 EPDFEGAKYV 292 Score = 35.1 bits (77), Expect = 2.2 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 9/78 (11%) Frame = -1 Query: 243 KGRAKVCPVLCSP-EDQAELWRNISIID--VFATDHAPHTVEEKNS------ENPPPGYP 91 +G VC P E QA LWR + D V +TDH P + P G P Sbjct: 287 EGAKYVCSTPLRPKEHQAALWRGLRTNDLQVVSTDHCPFCFSGQKELGRGDFSRIPNGMP 346 Query: 90 GLETILPLLLNAVHQGRL 37 G+E + LL AV +G + Sbjct: 347 GVENRMDLLHQAVVEGHI 364 >UniRef50_O32137 Cluster: Allantoinase; n=1; Bacillus subtilis|Rep: Allantoinase - Bacillus subtilis Length = 446 Score = 46.8 bits (106), Expect = 7e-04 Identities = 19/60 (31%), Positives = 34/60 (56%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE E I A + PVH H++ + + +I+ AK+ G+ V+ E CPH++ + +D+ Sbjct: 216 AEVEAVYRTIQYAKVTGCPVHFVHISTAKAVRLIREAKQEGLDVSVETCPHYVLFSHDDL 275 >UniRef50_Q831D1 Cluster: D-hydantoinase; n=6; Firmicutes|Rep: D-hydantoinase - Enterococcus faecalis (Streptococcus faecalis) Length = 457 Score = 46.4 bits (105), Expect = 9e-04 Identities = 19/57 (33%), Positives = 34/57 (59%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261 E E A +++A + D PV+I H++ K + ++ A++RG V E CP +L L+ + Sbjct: 217 EAEAVARYLMIAEMADLPVNIVHLSTKRSLEAVERARQRGQSVYVETCPQYLLLDDH 273 >UniRef50_A4M847 Cluster: Dihydropyrimidinase; n=1; Petrotoga mobilis SJ95|Rep: Dihydropyrimidinase - Petrotoga mobilis SJ95 Length = 451 Score = 46.4 bits (105), Expect = 9e-04 Identities = 29/75 (38%), Positives = 41/75 (54%), Gaps = 7/75 (9%) Frame = -1 Query: 222 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEE----KNSENPPPGYPGLETILPLLL 61 P L +D LW I +IDV ATDH + E+ KNS + PG PG+ET+L L Sbjct: 286 PPLRESQDNEALWEGIQKGLIDVIATDHCAYNAEQKSMGKNSLDIFPGIPGVETLLALTY 345 Query: 60 N-AVHQGRLTIEDLL 19 V++G ++I L+ Sbjct: 346 TYGVNKGLISINRLV 360 >UniRef50_Q6A916 Cluster: Dihydroorotase; n=1; Propionibacterium acnes|Rep: Dihydroorotase - Propionibacterium acnes Length = 445 Score = 46.0 bits (104), Expect = 0.001 Identities = 20/65 (30%), Positives = 33/65 (50%) Frame = -2 Query: 449 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 P+ E + A +++A H+CH + ++ I ++ +E G VT E PHHL L Sbjct: 208 PMTRLTETVQVARDVMIAEETGAHYHLCHASTRQSIRTLRRGREDGANVTGEAAPHHLLL 267 Query: 269 NSNDI 255 +DI Sbjct: 268 ADDDI 272 Score = 38.7 bits (86), Expect = 0.18 Identities = 22/54 (40%), Positives = 27/54 (50%), Gaps = 3/54 (5%) Frame = -3 Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*D---LLPQXHWLVVLTMICAMPNTNP 680 G + PG +D+HVH+REPG K + W T ICAMPNT P Sbjct: 52 GGALVTPGMVDLHVHLREPGQEHKETIASGTAAAARGGW----TTICAMPNTVP 101 >UniRef50_Q3ZYB9 Cluster: Dihydroorotase, multifunctional complex type; n=4; Bacteria|Rep: Dihydroorotase, multifunctional complex type - Dehalococcoides sp. (strain CBDB1) Length = 428 Score = 46.0 bits (104), Expect = 0.001 Identities = 31/76 (40%), Positives = 39/76 (51%), Gaps = 4/76 (5%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67 AKV P L + D L + ID ATDHAPHT +K E G GLET L Sbjct: 276 AKVNPPLRTQTDIEALIAGLKDGTIDAIATDHAPHTRNDKLCEFGLAANGISGLETALAS 335 Query: 66 LLNAVHQGRLTIEDLL 19 L+ VH G+L++ L+ Sbjct: 336 LMGLVHSGKLSLSLLI 351 Score = 43.2 bits (97), Expect = 0.008 Identities = 14/41 (34%), Positives = 27/41 (65%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +H+CH++ + +++ AK G++V+ EV PHHL L ++ Sbjct: 229 LHLCHISTAGSVELVRQAKAAGIRVSAEVTPHHLTLTEAEV 269 Score = 42.7 bits (96), Expect = 0.011 Identities = 27/67 (40%), Positives = 35/67 (52%), Gaps = 1/67 (1%) Frame = -3 Query: 823 VKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDY-A 647 V PGFID+HVH+REPG K + + T IC MPNTNP+ D+ Sbjct: 52 VVCPGFIDLHVHLREPGFEGKETI-ESGCKAAAAGGFTSICPMPNTNPAADCLPVIDFIK 110 Query: 646 STLARVS 626 +T +VS Sbjct: 111 NTATKVS 117 >UniRef50_A7HCE8 Cluster: Dihydroorotase, multifunctional complex type; n=10; Deltaproteobacteria|Rep: Dihydroorotase, multifunctional complex type - Anaeromyxobacter sp. Fw109-5 Length = 433 Score = 46.0 bits (104), Expect = 0.001 Identities = 21/51 (41%), Positives = 29/51 (56%) Frame = -2 Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 I + L +H+ HV+ K + I+ AK RG+ VT EV PHHL L D+ Sbjct: 221 IALVELTGGRLHVAHVSTKGAVRAIRDAKARGLPVTGEVTPHHLALTDEDV 271 Score = 43.2 bits (97), Expect = 0.008 Identities = 32/77 (41%), Positives = 39/77 (50%), Gaps = 1/77 (1%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTLA 635 PGFID+HVH+REPG K + T +CAMPNT P V+ A LA Sbjct: 57 PGFIDLHVHLREPGQEYKETI-ATGARAAVAGGFTAVCAMPNTKP--VNDNASVTELVLA 113 Query: 634 RVSARCDYALY-VGASS 587 R +A +Y VGA S Sbjct: 114 RAAAAGLARVYPVGAIS 130 Score = 42.3 bits (95), Expect = 0.015 Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 4/70 (5%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64 K+ P L S ED ++ +D ATDHAPH+ EK+ E G GLET P+ Sbjct: 281 KMNPPLRSAEDVRACREGLADGTLDAIATDHAPHSAVEKDVEFDAAANGITGLETAFPVC 340 Query: 63 LNAVHQGRLT 34 L+ V G L+ Sbjct: 341 LDLVRAGALS 350 >UniRef50_A4AEE1 Cluster: Dihydroorotase and related cyclic amidohydrolase; n=1; marine actinobacterium PHSC20C1|Rep: Dihydroorotase and related cyclic amidohydrolase - marine actinobacterium PHSC20C1 Length = 470 Score = 46.0 bits (104), Expect = 0.001 Identities = 27/68 (39%), Positives = 42/68 (61%), Gaps = 8/68 (11%) Frame = -1 Query: 207 PED-QAELWRNI--SIIDVFATDHAPHTVEEKN---SE--NPPPGYPGLETILPLLLNAV 52 P+D +A +W + ID+ ++DHAPHT EEK +E G PG++ L+L+AV Sbjct: 296 PDDNRAAIWEGMRDGTIDIASSDHAPHTREEKEIGWTEMWKAHTGTPGIQYYYELMLDAV 355 Query: 51 HQGRLTIE 28 ++G LT+E Sbjct: 356 NRGELTLE 363 Score = 40.7 bits (91), Expect = 0.045 Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Frame = -2 Query: 410 VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS-NDITKL 246 V+ +A PVHI H+ + I ++ AK GV VTCEV FL++ ND+ L Sbjct: 231 VLRLAEASGCPVHIAHIQTRRSIEAVRRAKANGVDVTCEVNHWAPFLSTWNDVQTL 286 Score = 40.3 bits (90), Expect = 0.059 Identities = 25/57 (43%), Positives = 29/57 (50%), Gaps = 2/57 (3%) Frame = -3 Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVD 668 G +V LPG +DVHVH REPG K D+L +T I MPN P VD Sbjct: 50 GRLV-LPGMVDVHVHTREPGYEHKD---DILTTTRQAAAGGVTTIFGMPNLKPPTVD 102 >UniRef50_A2R282 Cluster: Contig An13c0120, complete genome; n=3; Trichocomaceae|Rep: Contig An13c0120, complete genome - Aspergillus niger Length = 502 Score = 46.0 bits (104), Expect = 0.001 Identities = 23/57 (40%), Positives = 33/57 (57%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264 AE E T VI ++ L D P+ I H++ K ++AA+ R + V E CPH+LF S Sbjct: 225 AEDEATYRVISLSELADVPILIVHMSSKLAAAHVRAAQTRLLPVHAETCPHYLFFTS 281 >UniRef50_A3DKS9 Cluster: Amidohydrolase; n=1; Staphylothermus marinus F1|Rep: Amidohydrolase - Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) Length = 447 Score = 46.0 bits (104), Expect = 0.001 Identities = 18/46 (39%), Positives = 26/46 (56%) Frame = -2 Query: 386 DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITK 249 + P+HI HV+ E I IK + +G ++T E CPH L+ D K Sbjct: 222 EAPLHIAHVSSSEGIEAIKFLRRKGTRITAETCPHFLYFTREDSKK 267 >UniRef50_Q2JER9 Cluster: Allantoinase; n=5; Bacteria|Rep: Allantoinase - Frankia sp. (strain CcI3) Length = 453 Score = 45.6 bits (103), Expect = 0.002 Identities = 21/73 (28%), Positives = 39/73 (53%) Frame = -2 Query: 473 FQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCE 294 F SW P AE E AA+ +++ +H+ H+A + + + AA++ G+ +T E Sbjct: 214 FASWLASRPPA--AETEAVAALAALSAASGARLHVLHLAAADALDDVLAARDAGLPMTVE 271 Query: 293 VCPHHLFLNSNDI 255 CPH+L + ++ Sbjct: 272 TCPHYLTFTAEEV 284 >UniRef50_A6LUT2 Cluster: Dihydropyrimidinase; n=3; cellular organisms|Rep: Dihydropyrimidinase - Clostridium beijerinckii NCIMB 8052 Length = 455 Score = 45.6 bits (103), Expect = 0.002 Identities = 30/82 (36%), Positives = 41/82 (50%), Gaps = 8/82 (9%) Frame = -1 Query: 255 YKIGKGRAKVC-PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK-----NSENPPP 100 YK GR VC P + E Q LW+ I ID ATDH P EK + P Sbjct: 276 YKREDGRNFVCSPPMKGQESQDALWKAIKSGDIDTVATDHCPFQSYEKDWGKDDFTKIPN 335 Query: 99 GYPGLETILPLLLNAVHQGRLT 34 G G+E + P +L+A ++G++T Sbjct: 336 GCAGVENLYPYMLSAANEGKIT 357 Score = 42.3 bits (95), Expect = 0.015 Identities = 31/100 (31%), Positives = 48/100 (48%) Frame = -2 Query: 536 DVLK*NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVA 357 D++ N NFL E T H+ S P+ + AE +K A + +A + P+++ H+A Sbjct: 189 DLIDLNIENFLKEGKTSAWYHYLSRPEFV----EAEADKRA--VHLAKSIGAPLYLVHMA 242 Query: 356 RKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKG 237 KE + AK G + E CP +L D+ K E G Sbjct: 243 DKEGLETAIEAKREGHDIYVETCPQYLEFTC-DVYKREDG 281 >UniRef50_Q9RKU5 Cluster: Probable allantoinase; n=8; Actinomycetales|Rep: Probable allantoinase - Streptomyces coelicolor Length = 445 Score = 45.6 bits (103), Expect = 0.002 Identities = 19/60 (31%), Positives = 34/60 (56%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE A ++ A + VH+ H++ + + +I A+ GV+VT E CPH+L L + ++ Sbjct: 215 AEDTAIATLLAQAKRFNARVHVLHLSSSDALPLIAEARADGVRVTVETCPHYLTLTAEEV 274 >UniRef50_UPI0001597BA8 Cluster: PucH; n=1; Bacillus amyloliquefaciens FZB42|Rep: PucH - Bacillus amyloliquefaciens FZB42 Length = 454 Score = 45.2 bits (102), Expect = 0.002 Identities = 22/62 (35%), Positives = 31/62 (50%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE E I A +H H++ K +L I+ AK+ G+ VT E CPH+L + D Sbjct: 216 AECEAVQRAIEYARATGCALHFVHISTKRAVLSIQQAKKDGLDVTVETCPHYLLFSFEDF 275 Query: 254 TK 249 K Sbjct: 276 LK 277 >UniRef50_Q67Q00 Cluster: Dihydroorotase; n=6; Bacteria|Rep: Dihydroorotase - Symbiobacterium thermophilum Length = 434 Score = 45.2 bits (102), Expect = 0.002 Identities = 30/76 (39%), Positives = 42/76 (55%), Gaps = 5/76 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPP--GYPGLETILPLL 64 K+ P L D+ + ++ IDV ATDHAPH V+EK+ E P G GLET + L Sbjct: 280 KMNPPLREEADRQAILEGLADGTIDVIATDHAPHHVDEKDVEYPLAAFGITGLETAVGLA 339 Query: 63 LN-AVHQGRLTIEDLL 19 L+ V G + +E L+ Sbjct: 340 LDRLVRPGLIRLEQLI 355 Score = 39.9 bits (89), Expect = 0.078 Identities = 18/63 (28%), Positives = 31/63 (49%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE A IL+A VH+ H++ + + +++ K +G +VT E PHH L + Sbjct: 211 AEEVHVARDILLALETGARVHLQHLSSRRSVELVRWGKAQGARVTAEATPHHFTLTDQAV 270 Query: 254 TKL 246 + Sbjct: 271 ADM 273 Score = 34.7 bits (76), Expect = 2.9 Identities = 21/50 (42%), Positives = 25/50 (50%) Frame = -3 Query: 823 VKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSI 674 V PGFIDVHVH+R PG K + ++C MPNT P I Sbjct: 53 VVAPGFIDVHVHLRVPGQEYKEDMRTGTAAAVRGGFVGVVC-MPNTRPVI 101 >UniRef50_A3ESI6 Cluster: Dihydroorotase; n=3; Bacteria|Rep: Dihydroorotase - Leptospirillum sp. Group II UBA Length = 438 Score = 45.2 bits (102), Expect = 0.002 Identities = 31/76 (40%), Positives = 39/76 (51%), Gaps = 4/76 (5%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67 AK+ P L + ED+ + + ID+ ATDHAPH EK E P G GLET L Sbjct: 283 AKMNPPLRTEEDRLAIIEGLRDGTIDMIATDHAPHAPFEKEREFDQAPFGIIGLETAFSL 342 Query: 66 LLNAVHQGRLTIEDLL 19 L V+ G L + LL Sbjct: 343 GLQLVNSGVLDLSMLL 358 Score = 35.9 bits (79), Expect = 1.3 Identities = 12/41 (29%), Positives = 24/41 (58%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +H+ H++ + +++ AK+R + VT E CPH+ L + Sbjct: 236 LHVAHLSTAGGVRLVREAKKRHLHVTAETCPHYFSLTDEAV 276 Score = 33.5 bits (73), Expect = 6.8 Identities = 17/45 (37%), Positives = 22/45 (48%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP 680 PG +DVH H REPG K + + T +C M NT+P Sbjct: 62 PGLVDVHAHFREPGFEYKETI-ESGSRAAVSGGFTAVCVMANTDP 105 >UniRef50_A1SH63 Cluster: Dihydropyrimidinase; n=1; Nocardioides sp. JS614|Rep: Dihydropyrimidinase - Nocardioides sp. (strain BAA-499 / JS614) Length = 467 Score = 45.2 bits (102), Expect = 0.002 Identities = 28/97 (28%), Positives = 49/97 (50%) Frame = -2 Query: 512 NFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILII 333 + ++E + +K + P P AE + AAV+ A+ D +++ H++ + + Sbjct: 198 SLVVEALAAGRKGPDAIPAVRPDSVEAEAIRRAAVLAAAA--DTSLYVVHLSSAAGLEAV 255 Query: 332 KAAKERGVKVTCEVCPHHLFLNSNDITKLEKGEQKYV 222 +AA+ G V E CPH+L+L D LE GE +V Sbjct: 256 RAARAVGADVHAETCPHYLYL---DQAHLEAGEPDFV 289 Score = 36.7 bits (81), Expect = 0.72 Identities = 28/88 (31%), Positives = 38/88 (43%), Gaps = 12/88 (13%) Frame = -1 Query: 258 HYKIGKGRAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNS---------- 115 H + G+ P L D+A LW I+ ++V ATDH P T ++ Sbjct: 280 HLEAGEPDFVCAPPLRGAADRAALWGAIAAGEVEVVATDHCPFTRADRRRGTGGDGWADF 339 Query: 114 ENPPPGYPGLETILPLLLNAVHQGRLTI 31 P G G+ET L L V GRLT+ Sbjct: 340 RQLPGGLSGVETRLALAYQGVVSGRLTL 367 >UniRef50_UPI00015BD532 Cluster: UPI00015BD532 related cluster; n=1; unknown|Rep: UPI00015BD532 UniRef100 entry - unknown Length = 424 Score = 44.8 bits (101), Expect = 0.003 Identities = 22/71 (30%), Positives = 35/71 (49%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 ++ GF+D+H H+R+PG K + + T++C MPNTNP I + + Y Sbjct: 52 LIACSGFVDIHAHLRDPGFTYKEDLESGMKAATFGGFTTIVC-MPNTNPPIDNESIISYI 110 Query: 646 STLARVSARCD 614 + A CD Sbjct: 111 LSKAEKIGICD 121 Score = 43.6 bits (98), Expect = 0.006 Identities = 21/59 (35%), Positives = 34/59 (57%) Frame = -2 Query: 440 THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNS 264 ++AE A +++ +HI H++ + I+K KE+G +TCEV P+HL LNS Sbjct: 209 SYAEDVMVARDCILSYKTGGKLHIQHLSSSLSVDIVKFFKEKGANITCEVNPNHLALNS 267 Score = 39.5 bits (88), Expect = 0.10 Identities = 19/52 (36%), Positives = 29/52 (55%), Gaps = 1/52 (1%) Frame = -1 Query: 171 IIDVFATDHAPHTVEEK-NSENPPPGYPGLETILPLLLNAVHQGRLTIEDLL 19 +ID ATDHAPH EK + G G + LP++++ V G + I+ L+ Sbjct: 300 VIDCIATDHAPHAKNEKLHPIKGAAGMLGFQVALPIIMSLVKDGVIDIKSLI 351 >UniRef50_Q89Q35 Cluster: D-hydantoinase; n=20; Proteobacteria|Rep: D-hydantoinase - Bradyrhizobium japonicum Length = 486 Score = 44.8 bits (101), Expect = 0.003 Identities = 21/62 (33%), Positives = 37/62 (59%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 ERE T I A ++ P+ I HV+ +E + ++ A++RG+ V E CP ++ L ++D+ Sbjct: 236 EREATHRAISHAEIVGVPIMIVHVSGREAMEQVRWAQQRGLPVHAETCPQYITLTADDMK 295 Query: 251 KL 246 L Sbjct: 296 GL 297 Score = 35.9 bits (79), Expect = 1.3 Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 18/81 (22%) Frame = -1 Query: 216 LCSP-----EDQAELWRNIS--IIDVFATDHAPHTVEE-KNSENP---------PPGYPG 88 +CSP E Q +W I+ + F++DH P ++ K P P G PG Sbjct: 307 VCSPPPRDAESQQAIWEGITSGVFQTFSSDHCPFRYDDPKGKLTPNSRTSFRWVPNGIPG 366 Query: 87 LETILPLLLN-AVHQGRLTIE 28 +ET LP+L + V +GR++++ Sbjct: 367 VETRLPILFSEGVSKGRISLQ 387 >UniRef50_A6E6Y3 Cluster: Dihydroorotase; n=1; Pedobacter sp. BAL39|Rep: Dihydroorotase - Pedobacter sp. BAL39 Length = 420 Score = 44.8 bits (101), Expect = 0.003 Identities = 19/53 (35%), Positives = 32/53 (60%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 276 AE + I +A+ D P+HI ++ + +IK AK+ G+K++C+V HHL Sbjct: 210 AEEMHISRDIFLAAYHDAPLHISNITTAGAVSLIKKAKKDGLKISCDVAAHHL 262 >UniRef50_Q5KFL1 Cluster: Dihydropyrimidinase, putative; n=2; Filobasidiella neoformans|Rep: Dihydropyrimidinase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 471 Score = 44.8 bits (101), Expect = 0.003 Identities = 21/61 (34%), Positives = 31/61 (50%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 E E T+ I++A ++ PV HV +I+ A+ RG V E CP +L L D+ Sbjct: 245 EMEATSRAIVLAEMIQNPVLFVHVGSASAAEVIRNAQTRGFPVFAETCPQYLHLTWEDLK 304 Query: 251 K 249 K Sbjct: 305 K 305 >UniRef50_UPI000038E4AB Cluster: hypothetical protein Faci_03000487; n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical protein Faci_03000487 - Ferroplasma acidarmanus fer1 Length = 457 Score = 44.4 bits (100), Expect = 0.004 Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 8/79 (10%) Frame = -1 Query: 240 GRAKVC-PVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENP----PPGYPGLE 82 G +C P L ED +W IS I +DH P +K P P G PG+E Sbjct: 283 GNLYLCSPPLRKKEDINAMWNAISSGKIQAVGSDHVPFLAYQKKKGIPFNKVPNGIPGIE 342 Query: 81 TILPLLLN-AVHQGRLTIE 28 T LPLL + V +GR+T+E Sbjct: 343 TRLPLLFSEGVQKGRITLE 361 >UniRef50_Q89K18 Cluster: Blr5100 protein; n=43; Alphaproteobacteria|Rep: Blr5100 protein - Bradyrhizobium japonicum Length = 436 Score = 44.4 bits (100), Expect = 0.004 Identities = 27/75 (36%), Positives = 40/75 (53%), Gaps = 4/75 (5%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64 K+ P L + +D+ L ++ +IDV +DH P VE K PG GLET+LP Sbjct: 288 KLSPPLRTEDDRRALVAAVASGLIDVIMSDHNPQDVEVKRLPFAEAAPGAVGLETMLPAG 347 Query: 63 LNAVHQGRLTIEDLL 19 L +H G L ++ L+ Sbjct: 348 LRLMHNGELDLKTLI 362 >UniRef50_A6PU21 Cluster: Dihydroorotase, multifunctional complex type; n=1; Victivallis vadensis ATCC BAA-548|Rep: Dihydroorotase, multifunctional complex type - Victivallis vadensis ATCC BAA-548 Length = 369 Score = 44.4 bits (100), Expect = 0.004 Identities = 21/64 (32%), Positives = 36/64 (56%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +E A I++A + +H+ HV+ KE + +++ A+ +G+ VT E PHHL L I Sbjct: 207 SEELMIARNIILARQIGWKIHMQHVSVKESVELLRNARAKGIPVTGEATPHHLTLTDECI 266 Query: 254 TKLE 243 K + Sbjct: 267 KKYD 270 Score = 40.3 bits (90), Expect = 0.059 Identities = 25/70 (35%), Positives = 32/70 (45%) Frame = -3 Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFD 653 G V PGFID+HVH+R+PG N+ T + AMPNTNP A + Sbjct: 46 GGKVLSPGFIDLHVHLRQPGNNMAETIASGTAAAA-AGGFTSVVAMPNTNPPADTAGAIE 104 Query: 652 YASTLARVSA 623 + A A Sbjct: 105 FLRQTAAKKA 114 Score = 39.1 bits (87), Expect = 0.14 Identities = 26/59 (44%), Positives = 32/59 (54%), Gaps = 4/59 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPL 67 K+ P L S ED+ L ++ I ATDHAPHT+ K E P G GLET LP+ Sbjct: 274 KMNPPLRSEEDRLALIAGVADGTITAIATDHAPHTMTAKMVEFDYAPFGIIGLETALPV 332 >UniRef50_Q8NQ39 Cluster: Dihydroorotase; n=35; Actinomycetales|Rep: Dihydroorotase - Corynebacterium glutamicum (Brevibacterium flavum) Length = 447 Score = 44.4 bits (100), Expect = 0.004 Identities = 20/55 (36%), Positives = 30/55 (54%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 AE +MA VHICH + + + +++ AK +G+ +T EV PHHL L Sbjct: 224 AEESIVVRDAIMARDYGNRVHICHASTEGTVELLRWAKSQGIPITAEVTPHHLTL 278 Score = 42.7 bits (96), Expect = 0.011 Identities = 27/62 (43%), Positives = 34/62 (54%), Gaps = 4/62 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEK--NSENPPPGYPGLETILPLL 64 KV P L D L + + IDV ATDHAPH E+K EN PG GLET L ++ Sbjct: 291 KVNPPLRESRDAEALKKALLDGTIDVVATDHAPHGSEDKCCEFENAKPGMLGLETSLSII 350 Query: 63 LN 58 ++ Sbjct: 351 VD 352 Score = 35.9 bits (79), Expect = 1.3 Identities = 13/17 (76%), Positives = 16/17 (94%) Frame = -3 Query: 823 VKLPGFIDVHVHVREPG 773 V LPGF+D+HVH+REPG Sbjct: 64 VLLPGFVDMHVHLREPG 80 >UniRef50_Q1IJ01 Cluster: Dihydroorotase, multifunctional complex type; n=1; Acidobacteria bacterium Ellin345|Rep: Dihydroorotase, multifunctional complex type - Acidobacteria bacterium (strain Ellin345) Length = 429 Score = 44.0 bits (99), Expect = 0.005 Identities = 21/43 (48%), Positives = 25/43 (58%), Gaps = 2/43 (4%) Frame = -1 Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQ 46 +D ATDHAPH EK E P G GLET LPL + +H+ Sbjct: 303 LDCIATDHAPHAYHEKEQEFDRAPFGIIGLETALPLAITVLHK 345 Score = 41.5 bits (93), Expect = 0.025 Identities = 22/50 (44%), Positives = 29/50 (58%) Frame = -3 Query: 829 NIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNP 680 ++V PGFID+HVH+REPG K + T +CAMPNT+P Sbjct: 54 HLVVAPGFIDLHVHLREPGQAHKETI-ASGTRSAAAGGFTSVCAMPNTSP 102 Score = 37.9 bits (84), Expect = 0.31 Identities = 14/41 (34%), Positives = 25/41 (60%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +H+ H++ E + ++ AK+ ++VT EV PHH L +I Sbjct: 232 LHVAHISTAEALDAVRRAKKENLRVTAEVTPHHFTLLDENI 272 >UniRef50_Q18WQ5 Cluster: Dihydroorotase, multifunctional complex type; n=2; Desulfitobacterium hafniense|Rep: Dihydroorotase, multifunctional complex type - Desulfitobacterium hafniense (strain DCB-2) Length = 444 Score = 44.0 bits (99), Expect = 0.005 Identities = 21/60 (35%), Positives = 32/60 (53%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE A V +A V I H++ + + I++ AKE G KV E+CP +L+L N + Sbjct: 211 AEAISVANVCFIAKETGAHVTIAHLSHPDVVGIVQEAKEAGAKVLAEICPQYLYLEENTL 270 >UniRef50_A2U746 Cluster: Dihydropyrimidinase; n=3; Bacillus|Rep: Dihydropyrimidinase - Bacillus coagulans 36D1 Length = 471 Score = 44.0 bits (99), Expect = 0.005 Identities = 24/71 (33%), Positives = 37/71 (52%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE E T I +A + D +++ HV E + I A+ +G KV E CP +L L+ + + Sbjct: 216 AEGEATHRAIELAHMADSQLYVVHVTCAEAVKQIAEARAKGYKVWGETCPQYLVLDQSYL 275 Query: 254 TKLEKGEQKYV 222 K + KYV Sbjct: 276 EKPDFEGAKYV 286 >UniRef50_Q9P903 Cluster: Dihydropyrimidinase; n=2; Saccharomycetaceae|Rep: Dihydropyrimidinase - Saccharomyces kluyveri (Yeast) (Saccharomyces silvestris) Length = 542 Score = 44.0 bits (99), Expect = 0.005 Identities = 22/61 (36%), Positives = 35/61 (57%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 E E T I +A+ +D P+ HV+ + +IK A+ +G+KV E CP + L S+ IT Sbjct: 233 EGEATNRAITLATTMDTPILFVHVSSPQAAEVIKQAQTKGLKVYAETCPQYALL-SDAIT 291 Query: 251 K 249 + Sbjct: 292 R 292 >UniRef50_A3LNF2 Cluster: Allantoinase; n=2; Saccharomycetales|Rep: Allantoinase - Pichia stipitis (Yeast) Length = 579 Score = 44.0 bits (99), Expect = 0.005 Identities = 18/42 (42%), Positives = 28/42 (66%) Frame = -2 Query: 380 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 P+HI H+A E + +I+AAK +G+ +T E C H+L L + I Sbjct: 357 PLHIVHLATHEAVPLIRAAKAKGLPITAETCFHYLSLYAESI 398 >UniRef50_A1C896 Cluster: Aminohydrolase; n=6; cellular organisms|Rep: Aminohydrolase - Aspergillus clavatus Length = 493 Score = 44.0 bits (99), Expect = 0.005 Identities = 21/61 (34%), Positives = 31/61 (50%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 E E T I + L+ P+ I HV+ II+ A+ G+ V E CP +LFL ++ Sbjct: 228 ESEATNRAIALGQLIQTPILIVHVSSPSAAEIIRQAQTNGLPVYAETCPQYLFLTRAELD 287 Query: 251 K 249 K Sbjct: 288 K 288 >UniRef50_Q73KW0 Cluster: Dihydroorotase, putative; n=1; Treponema denticola|Rep: Dihydroorotase, putative - Treponema denticola Length = 371 Score = 43.6 bits (98), Expect = 0.006 Identities = 18/67 (26%), Positives = 32/67 (47%) Frame = -2 Query: 449 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 P E K ++ + +H+CH++ KE I ++ AK+ G+ ++C HH L Sbjct: 163 PPIAETESIKDQIELMQSEDFKGHLHVCHISTKEGIRLVAEAKKSGLSISCGATAHHALL 222 Query: 269 NSNDITK 249 N + K Sbjct: 223 NIDSYKK 229 >UniRef50_A5DY43 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 617 Score = 43.6 bits (98), Expect = 0.006 Identities = 21/61 (34%), Positives = 37/61 (60%), Gaps = 1/61 (1%) Frame = -2 Query: 431 EREKTAAVILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 E A +I ++L+ P+HI H+A E + +++AAK +G+ +T E C H+L L + I Sbjct: 378 ETTAIAEIINCSTLIPSVPLHIVHLATHEAVPLLRAAKAKGLPITAETCFHYLSLCAEKI 437 Query: 254 T 252 + Sbjct: 438 S 438 >UniRef50_Q1VPD0 Cluster: Dihydroorotase; n=11; Bacteroidetes|Rep: Dihydroorotase - Psychroflexus torquis ATCC 700755 Length = 452 Score = 43.2 bits (97), Expect = 0.008 Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 2/87 (2%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAST 641 PG ID VH R+PG KG DL + + +T MPNT P+I+ + Sbjct: 54 PGIIDGQVHFRDPGLTHKG---DLYTESKAAIAGGVTSFIDMPNTVPNILTVESLKEKFD 110 Query: 640 LARVSARCDYALYVGASSTNYDTICEL 560 +A + +Y+ ++G + N D + ++ Sbjct: 111 IASKKSLANYSFFLGVNGDNIDEVVKM 137 Score = 39.5 bits (88), Expect = 0.10 Identities = 20/57 (35%), Positives = 32/57 (56%), Gaps = 2/57 (3%) Frame = -1 Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRIRH 4 ID+ TDHAPHT+EEK G P ++ L +L QG +++E ++ ++ H Sbjct: 306 IDLITTDHAPHTLEEKQQPYFQSMSGAPMVQHTLNCMLEFYKQGLISLEKIVEKMCH 362 >UniRef50_Q9RV76 Cluster: Probable allantoinase; n=4; Bacteria|Rep: Probable allantoinase - Deinococcus radiodurans Length = 448 Score = 43.2 bits (97), Expect = 0.008 Identities = 20/68 (29%), Positives = 34/68 (50%) Frame = -2 Query: 449 PVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 PV T E + A +L A +H+ HV+ + + K++G+ VT E CPH+L Sbjct: 213 PVVTELEAVQRA--LLFAQDTGAALHLVHVSSGAAVALAYEGKQKGIDVTIETCPHYLHF 270 Query: 269 NSNDITKL 246 D+ ++ Sbjct: 271 TGEDVERV 278 Score = 39.1 bits (87), Expect = 0.14 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 1/87 (1%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMP-NTNPSIVDRTAFDYASTL 638 PG +D HVH+ EPG F + Q T MP N++P ++ R F+ + L Sbjct: 54 PGVLDDHVHLNEPGRTHWEGF-ETGTQALAAGGATSFLDMPLNSSPPVLTRERFEDKARL 112 Query: 637 ARVSARCDYALYVGASSTNYDTICELA 557 + D+ L+ G + N D + +LA Sbjct: 113 GEEKSLIDFGLWGGLTPLNLDQLDDLA 139 >UniRef50_Q2SMZ8 Cluster: Dihydroorotase and related cyclic amidoHydrolase; n=3; Gammaproteobacteria|Rep: Dihydroorotase and related cyclic amidoHydrolase - Hahella chejuensis (strain KCTC 2396) Length = 455 Score = 42.7 bits (96), Expect = 0.011 Identities = 22/49 (44%), Positives = 28/49 (57%) Frame = -2 Query: 416 AAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 AA A +D VHI H++ E + I AAKE G+ T E CPH+L L Sbjct: 223 AARDFKAQGVDCKVHIVHLSSAEALAAIGAAKESGLTFTVETCPHYLTL 271 Score = 34.7 bits (76), Expect = 2.9 Identities = 12/20 (60%), Positives = 15/20 (75%) Frame = -3 Query: 832 GNIVKLPGFIDVHVHVREPG 773 GN V +PG +D HVH+ EPG Sbjct: 49 GNDVVMPGLVDTHVHINEPG 68 >UniRef50_A4EA66 Cluster: Putative uncharacterized protein; n=1; Collinsella aerofaciens ATCC 25986|Rep: Putative uncharacterized protein - Collinsella aerofaciens ATCC 25986 Length = 455 Score = 42.7 bits (96), Expect = 0.011 Identities = 26/71 (36%), Positives = 41/71 (57%), Gaps = 2/71 (2%) Frame = -2 Query: 431 EREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVK-VTCEVCPHHLFLNSND 258 E E + ++ +A L D PV++ H++ K + I+AAK RG K + E CP +L L +D Sbjct: 215 EGEAVSRLLYLAHLAGDAPVNVVHLSTKLGLEAIRAAKARGQKNIYVETCPQYLML--DD 272 Query: 257 ITKLEKGEQKY 225 LE+GE + Sbjct: 273 TCYLEQGEDGF 283 >UniRef50_A4C048 Cluster: Amidohydrolase family, putative; n=10; Bacteroidetes|Rep: Amidohydrolase family, putative - Polaribacter irgensii 23-P Length = 441 Score = 42.7 bits (96), Expect = 0.011 Identities = 18/64 (28%), Positives = 38/64 (59%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE + A+ +L+ +HI ++ + + +IK AK++G++V+C V HHL L +++ Sbjct: 232 AEELQIASNLLILEYTGGKLHIPTISTAKSVTLIKDAKKKGLQVSCSVAAHHLVLTDDEL 291 Query: 254 TKLE 243 + + Sbjct: 292 HEFD 295 >UniRef50_Q64E81 Cluster: Dihydroorotase; n=1; uncultured archaeon GZfos13E1|Rep: Dihydroorotase - uncultured archaeon GZfos13E1 Length = 456 Score = 42.7 bits (96), Expect = 0.011 Identities = 30/111 (27%), Positives = 52/111 (46%), Gaps = 5/111 (4%) Frame = -3 Query: 835 HGNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV---LTMICAMPNTNPSIVDR 665 HG ++ PGFID+H H+RE ++ K + + + +T + MPNT ++ Sbjct: 52 HGCLI-FPGFIDIHAHLREDSSH-KWDYKEDFGTGSAAAIHGGITTVVDMPNTPLPGINA 109 Query: 664 TAFDYASTLARVSAR--CDYALYVGASSTNYDTICELAPQAAALKMYLNET 518 LAR +++ D Y G + +N I ++ + K+YL ET Sbjct: 110 DRIRKKRELARSTSKGLIDVFFYGGVTESNLSAIADMQKEVVGYKIYLCET 160 Score = 38.7 bits (86), Expect = 0.18 Identities = 22/63 (34%), Positives = 36/63 (57%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKGEQKYVQYYVVLKT 198 ++I HV+ E + +IK K V CEV PHHLF N+ D+ +Q +++ L+T Sbjct: 254 INIAHVSVYETLSMIKQYKN----VHCEVTPHHLFFNTADVL----AKQAFLKMNPPLRT 305 Query: 197 KQN 189 ++N Sbjct: 306 EEN 308 Score = 36.7 bits (81), Expect = 0.72 Identities = 18/32 (56%), Positives = 21/32 (65%), Gaps = 2/32 (6%) Frame = -1 Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLET 79 ID ATDHAPHT EEK+ + P G P L+T Sbjct: 321 IDFLATDHAPHTREEKSLDFSVAPAGVPNLDT 352 >UniRef50_A0RTM1 Cluster: Dihydroorotase; n=2; Thermoprotei|Rep: Dihydroorotase - Cenarchaeum symbiosum Length = 482 Score = 42.7 bits (96), Expect = 0.011 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 6/77 (7%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSEN---PPPGYPGLETILP 70 AKV P + + D +W I+ ID TDH + + K ++ G+PG T+LP Sbjct: 314 AKVMPPIRTSSDVDAVWAAITAGEIDTIGTDHVANRLGRKLGDDVWDSLAGFPGAGTLLP 373 Query: 69 LLLN-AVHQGRLTIEDL 22 LLL+ V++ R+T+E L Sbjct: 374 LLLSEGVNKNRITLEGL 390 >UniRef50_Q51551 Cluster: Dihydroorotase-like protein; n=14; Gammaproteobacteria|Rep: Dihydroorotase-like protein - Pseudomonas aeruginosa Length = 423 Score = 42.7 bits (96), Expect = 0.011 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 2/58 (3%) Frame = -1 Query: 171 IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRIRH 4 ++ A+ H PH + KN+ PG G E +LPL + V G L + LL R+ H Sbjct: 299 VVQAIASHHQPHEADAKNAPFAATEPGISGAELLLPLAMTLVQDGLLDLPTLLARLSH 356 >UniRef50_Q9WYH0 Cluster: Dihydroorotase; n=4; Thermotogaceae|Rep: Dihydroorotase - Thermotoga maritima Length = 376 Score = 42.7 bits (96), Expect = 0.011 Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 2/72 (2%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLN 58 K+ P L SPED+ L + +IDV ATDHAPH + + P G +E P Sbjct: 228 KINPPLGSPEDRRALIEAVKKDVIDVLATDHAPHHEKPDDFLTAPYGSTSIEIAFPAYYT 287 Query: 57 AVHQGRLTIEDL 22 A+ L ++ L Sbjct: 288 ALGDLELVVKKL 299 Score = 37.9 bits (84), Expect = 0.31 Identities = 19/40 (47%), Positives = 22/40 (55%) Frame = -2 Query: 374 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 HI HV K + +I K KV+CEV PHHLF DI Sbjct: 184 HIQHVTTKYSVEVISFLKNLA-KVSCEVTPHHLFFCYEDI 222 >UniRef50_Q8YRV3 Cluster: Dihydroorotase; n=8; Cyanobacteria|Rep: Dihydroorotase - Anabaena sp. (strain PCC 7120) Length = 435 Score = 42.3 bits (95), Expect = 0.015 Identities = 25/53 (47%), Positives = 28/53 (52%), Gaps = 3/53 (5%) Frame = -1 Query: 171 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL-LNAVHQGRLTIEDL 22 +ID A DHAP+T EEK PPG G E LPLL N V G T +L Sbjct: 317 VIDAIAIDHAPYTYEEKVQAFAEAPPGAIGFELALPLLWQNLVETGEFTALEL 369 Score = 34.3 bits (75), Expect = 3.9 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 1/66 (1%) Frame = -2 Query: 449 PVCTHAEREKTAAVI-LMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 273 P+ AE AA++ L+A+ + VHI V+ + +I AAK +G+ +T HL Sbjct: 222 PIPPSAETSAIAALLELVAASGNTQVHIMRVSTARSVELIAAAKAQGLPITASTTWLHLL 281 Query: 272 LNSNDI 255 L++ + Sbjct: 282 LDTKAV 287 >UniRef50_Q5FRG9 Cluster: Dihydroorotase; n=4; Rhodospirillales|Rep: Dihydroorotase - Gluconobacter oxydans (Gluconobacter suboxydans) Length = 433 Score = 42.3 bits (95), Expect = 0.015 Identities = 19/64 (29%), Positives = 34/64 (53%) Frame = -2 Query: 446 VCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267 V AE A + + ++ +H HV+ E + +I+ AK RG++VTC+ P + + Sbjct: 206 VPAEAEAIMIARDLRLTAMTGARLHFAHVSTAEGLDLIREAKSRGIRVTCDTAPPYFAMT 265 Query: 266 SNDI 255 +DI Sbjct: 266 EDDI 269 >UniRef50_A7B6D5 Cluster: Putative uncharacterized protein; n=1; Ruminococcus gnavus ATCC 29149|Rep: Putative uncharacterized protein - Ruminococcus gnavus ATCC 29149 Length = 462 Score = 42.3 bits (95), Expect = 0.015 Identities = 29/82 (35%), Positives = 45/82 (54%), Gaps = 9/82 (10%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAP-HTVEEKNSENP-----PPGYPGLE 82 +A + P L EDQ LW+ + +IDV ATDH P H +EK + P G PG+E Sbjct: 284 KAIMSPPLRKKEDQDALWQALKDGVIDVVATDHCPFHFGKEKQAGAQDFTACPNGAPGVE 343 Query: 81 TILPLLLN-AVHQGRLTIEDLL 19 + +L + V +GR+T+ ++ Sbjct: 344 ERMRILFSEGVMKGRITLPQMV 365 >UniRef50_Q4AGB4 Cluster: Dihydropyrimidinase; n=1; Chlorobium phaeobacteroides BS1|Rep: Dihydropyrimidinase - Chlorobium phaeobacteroides BS1 Length = 455 Score = 41.5 bits (93), Expect = 0.025 Identities = 20/67 (29%), Positives = 32/67 (47%) Frame = -2 Query: 461 PKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPH 282 P+ P H E E I +A P++I H++ K + +K A+ G V E CP Sbjct: 210 PQSRPA--HLETEAVEKAIQLAMQAHCPLYIVHLSAKSSLEAVKKARHNGANVLVETCPQ 267 Query: 281 HLFLNSN 261 +L L+ + Sbjct: 268 YLLLDES 274 >UniRef50_Q6CUK0 Cluster: Similar to sp|P32375 Saccharomyces cerevisiae YIR027c DAL1 allantoinase singleton; n=1; Kluyveromyces lactis|Rep: Similar to sp|P32375 Saccharomyces cerevisiae YIR027c DAL1 allantoinase singleton - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 532 Score = 41.5 bits (93), Expect = 0.025 Identities = 18/43 (41%), Positives = 27/43 (62%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITK 249 VHI H+A E + I+K AK+ G+ +T E C H+L L + + K Sbjct: 316 VHIVHLASMEALPILKRAKDMGLPITAETCFHYLSLAAERVPK 358 >UniRef50_A1CFB0 Cluster: Allantoinase Dal1, putative; n=11; Pezizomycotina|Rep: Allantoinase Dal1, putative - Aspergillus clavatus Length = 509 Score = 41.5 bits (93), Expect = 0.025 Identities = 17/42 (40%), Positives = 27/42 (64%) Frame = -2 Query: 380 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 P+HI H++ E I +++ A+ GVK+T E C H+L L + I Sbjct: 257 PLHIVHLSAMEVIPLLREARANGVKITAETCFHYLSLAAEQI 298 >UniRef50_A2BJ21 Cluster: Dihydroorotase; n=1; Hyperthermus butylicus DSM 5456|Rep: Dihydroorotase - Hyperthermus butylicus (strain DSM 5456 / JCM 9403) Length = 424 Score = 41.5 bits (93), Expect = 0.025 Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 1/80 (1%) Frame = -3 Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV-LTMICAMPNTNPSIVDRTAF 656 G IV LPG ID+HVH+R G + + + +T++ MPNT P + ++A Sbjct: 48 GGIV-LPGMIDLHVHLR--GLKLSYKEDEATSTRAAAASGITLVADMPNTMPPLRSKSAI 104 Query: 655 DYASTLARVSARCDYALYVG 596 D R + DYA+Y G Sbjct: 105 DAKLAALRRMSLVDYAVYAG 124 >UniRef50_Q2S0H8 Cluster: Dihydroorotase; n=1; Salinibacter ruber DSM 13855|Rep: Dihydroorotase - Salinibacter ruber (strain DSM 13855) Length = 430 Score = 41.1 bits (92), Expect = 0.034 Identities = 17/46 (36%), Positives = 27/46 (58%) Frame = -2 Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 I +A+ +H+ H++ + +++ AK GV VT EVC HHL L Sbjct: 220 IELAARTGGALHVAHISTARGVELVRRAKAHGVPVTAEVCTHHLTL 265 Score = 41.1 bits (92), Expect = 0.034 Identities = 29/74 (39%), Positives = 38/74 (51%), Gaps = 5/74 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64 K+ P L SP D A L ++ ID TDHAPH EK E + P G GLET L+ Sbjct: 280 KMHPPLRSPADVAALKEGLADGTIDAICTDHAPHASYEKQVEFAHAPFGILGLETAWGLI 339 Query: 63 -LNAVHQGRLTIED 25 + G L++E+ Sbjct: 340 GRELIEPGVLSVEE 353 Score = 33.5 bits (73), Expect = 6.8 Identities = 18/55 (32%), Positives = 28/55 (50%) Frame = -3 Query: 814 PGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDY 650 PG++D+HVH+REPG K + T + MPNT+P + R ++ Sbjct: 57 PGWMDMHVHLREPGYEHKETV-ATGSRAALAGGFTDVACMPNTDPPLHTRDVVEF 110 >UniRef50_Q26E93 Cluster: Dihydroorotase; n=1; Flavobacteria bacterium BBFL7|Rep: Dihydroorotase - Flavobacteria bacterium BBFL7 Length = 416 Score = 41.1 bits (92), Expect = 0.034 Identities = 22/69 (31%), Positives = 38/69 (55%) Frame = -2 Query: 458 KKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHH 279 K MP AE + A I +A+ +HI + + +IK AK++ ++C V +H Sbjct: 202 KTMPAI--AEEVQIARDIQVAAYTGARLHIPTITTAASVQLIKEAKKKYSNISCSVSTNH 259 Query: 278 LFLNSNDIT 252 LFL++ND++ Sbjct: 260 LFLDTNDLS 268 >UniRef50_Q9UX05 Cluster: Dihydroorotase; n=5; Sulfolobaceae|Rep: Dihydroorotase - Sulfolobus solfataricus Length = 390 Score = 41.1 bits (92), Expect = 0.034 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 2/70 (2%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLLLN 58 KV P + ++ L + I+ +D +DHAPH EK E PPG L +P +L Sbjct: 232 KVNPPIRDTNERLWLLQAINEVDTVVSDHAPHASFEKQQPYEICPPGIAALSFTVPFILT 291 Query: 57 AVHQGRLTIE 28 V +G ++I+ Sbjct: 292 LVSKGIISID 301 >UniRef50_Q930B0 Cluster: Allantoinase, putative; n=1; Sinorhizobium meliloti|Rep: Allantoinase, putative - Rhizobium meliloti (Sinorhizobium meliloti) Length = 195 Score = 40.7 bits (91), Expect = 0.045 Identities = 28/90 (31%), Positives = 40/90 (44%), Gaps = 1/90 (1%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMP-NTNPSIVDRTAFDY 650 ++ LPG +D HVH EPG F + + +T MP N P+ +D A Sbjct: 83 LLLLPGLVDAHVHFSEPGRGHWEGF-ETGSRAAAAGGITTFVEMPLNAQPATIDAAALVM 141 Query: 649 ASTLARVSARCDYALYVGASSTNYDTICEL 560 A+ S DYAL+ G N D + +L Sbjct: 142 KKAAAKQS-HIDYALWGGLVDDNLDDLADL 170 >UniRef50_A6DRU9 Cluster: Dihydroorotase; n=1; Lentisphaera araneosa HTCC2155|Rep: Dihydroorotase - Lentisphaera araneosa HTCC2155 Length = 460 Score = 40.7 bits (91), Expect = 0.045 Identities = 19/65 (29%), Positives = 34/65 (52%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 A TA + + + +CH + + + +++AAKERGV VT E P L+ +++ + Sbjct: 193 AANTATAFALYLIEKYELKGKLCHFSTGDGLELVRAAKERGVTVTVETTPQQLYWDTSSL 252 Query: 254 TKLEK 240 K K Sbjct: 253 DKNNK 257 >UniRef50_Q6C0N2 Cluster: Similar to sp|P32375 Saccharomyces cerevisiae Allantoinase; n=1; Yarrowia lipolytica|Rep: Similar to sp|P32375 Saccharomyces cerevisiae Allantoinase - Yarrowia lipolytica (Candida lipolytica) Length = 457 Score = 40.7 bits (91), Expect = 0.045 Identities = 19/44 (43%), Positives = 26/44 (59%) Frame = -2 Query: 386 DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 D +HI H+A E + IIK AKE GV ++ E C H+L + I Sbjct: 233 DVKLHIVHLATAEAVPIIKKAKEEGVPLSVETCFHYLHFAAESI 276 >UniRef50_Q8TXX9 Cluster: Dihydroorotase; n=1; Methanopyrus kandleri|Rep: Dihydroorotase - Methanopyrus kandleri Length = 426 Score = 40.7 bits (91), Expect = 0.045 Identities = 21/53 (39%), Positives = 31/53 (58%) Frame = -1 Query: 168 IDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRI 10 +DV A+DHAPH +E++ E+ P G G E ILP L + L++ D + I Sbjct: 291 VDVLASDHAPHILEDE-FEDVPSGVTGGEIILPAALTLHRRFGLSLRDAVAMI 342 Score = 33.9 bits (74), Expect = 5.1 Identities = 21/55 (38%), Positives = 29/55 (52%), Gaps = 3/55 (5%) Frame = -2 Query: 422 KTAAVILMASLLDR---PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267 +T AV L+A L R +H+ HV E + I K G +T +V PHHLF + Sbjct: 207 ETTAVGLLAGLKVRYPSRIHLSHVTLPESVKIAK-----GADITVDVTPHHLFFD 256 >UniRef50_Q1AVY7 Cluster: Dihydroorotase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: Dihydroorotase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 436 Score = 40.3 bits (90), Expect = 0.059 Identities = 24/54 (44%), Positives = 30/54 (55%), Gaps = 3/54 (5%) Frame = -1 Query: 171 IIDVFATDHAPHTVEEKN--SENPPPGYPGLETILPLLLNA-VHQGRLTIEDLL 19 I+D ATDHAPH EEK E PG+ G ET L V +GRL++ L+ Sbjct: 302 ILDFVATDHAPHAPEEKELPLEEAAPGFLGHETAFAALYTGLVLEGRLSLGRLV 355 >UniRef50_Q4FLQ3 Cluster: Dihydroorotase; n=2; Candidatus Pelagibacter ubique|Rep: Dihydroorotase - Pelagibacter ubique Length = 428 Score = 39.9 bits (89), Expect = 0.078 Identities = 24/75 (32%), Positives = 37/75 (49%), Gaps = 4/75 (5%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64 K+ P L + ED+ L + + IDV +DH P E+K G G+ET+L L Sbjct: 281 KLSPPLRTEEDRIALVQGLKDETIDVIVSDHKPEDEEQKRLTFAQASTGASGIETLLSLS 340 Query: 63 LNAVHQGRLTIEDLL 19 L H G + +E ++ Sbjct: 341 LELYHNGSVKLETII 355 >UniRef50_Q18S74 Cluster: Amidohydrolase; n=2; Desulfitobacterium hafniense|Rep: Amidohydrolase - Desulfitobacterium hafniense (strain DCB-2) Length = 449 Score = 39.9 bits (89), Expect = 0.078 Identities = 18/62 (29%), Positives = 33/62 (53%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 E E + +I A + I H++ + + ++ A+ RGV V CE H+L+L +D+ Sbjct: 218 EIENVSRMITFAEETGCKLIIAHISTAKAVELVAQARARGVDVYCETIGHYLYLTGDDVE 277 Query: 251 KL 246 +L Sbjct: 278 RL 279 >UniRef50_A6CS57 Cluster: Dihydropyrimidinase; n=1; Bacillus sp. SG-1|Rep: Dihydropyrimidinase - Bacillus sp. SG-1 Length = 475 Score = 39.9 bits (89), Expect = 0.078 Identities = 20/70 (28%), Positives = 35/70 (50%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 E E T + L D +++ HV+ E + I +A+ +G+ V E CP +L L+ + + Sbjct: 219 EGEATGRAAKLTGLADSQLYVVHVSCSEAVKQIASARSKGLNVWGETCPQYLVLDQSYLE 278 Query: 251 KLEKGEQKYV 222 + KYV Sbjct: 279 RPNFEGAKYV 288 >UniRef50_Q6KZ43 Cluster: Dihydroorotase; n=2; Thermoplasmatales|Rep: Dihydroorotase - Picrophilus torridus Length = 408 Score = 39.9 bits (89), Expect = 0.078 Identities = 27/71 (38%), Positives = 38/71 (53%), Gaps = 3/71 (4%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPHTVEEKNS-ENPPPGYPGLETILPLLL 61 KV P L S Q+ L + D+ ++DHAPH+ EK E PG G+ET +PL+L Sbjct: 244 KVNPPLRSRSAQSLLLNSYISGNFDILSSDHAPHSQNEKTDFEYALPGIIGVETRIPLML 303 Query: 60 NAVHQGRLTIE 28 V + L I+ Sbjct: 304 ALVSKKILPID 314 Score = 37.5 bits (83), Expect = 0.41 Identities = 29/103 (28%), Positives = 40/103 (38%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638 +P D HVH R+PG K F T I MPN I + AF + Sbjct: 44 MPAGTDSHVHFRDPGETYKEDF-STGTMSAIFGGTTTIIDMPNNKIRIDNYQAFSDKLAI 102 Query: 637 ARVSARCDYALYVGASSTNYDTICELAPQAAALKMYLNETFTT 509 A CD+ LY S D + ++ +K+Y+ T T Sbjct: 103 VSRKAYCDFGLY---SMFTGDNSLIIDKRSTGIKIYMGNTTNT 142 >UniRef50_Q2JMN8 Cluster: Dihydroorotase, putative; n=2; Synechococcus|Rep: Dihydroorotase, putative - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 448 Score = 39.1 bits (87), Expect = 0.14 Identities = 29/70 (41%), Positives = 37/70 (52%), Gaps = 4/70 (5%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNISIIDV-FATDHAPHTVEEKN--SENPPPGYPGLETILPLLL 61 ++ P L S D+ L I ++ ATDH P+T EEK + PPG GLE LPLL Sbjct: 301 RLLPPLPSAGDREALIAGIRSGNLGIATDHHPYTYEEKTLPFADAPPGAMGLELALPLLW 360 Query: 60 -NAVHQGRLT 34 + V G LT Sbjct: 361 HHLVETGSLT 370 >UniRef50_Q24PA5 Cluster: Putative uncharacterized protein; n=1; Desulfitobacterium hafniense Y51|Rep: Putative uncharacterized protein - Desulfitobacterium hafniense (strain Y51) Length = 446 Score = 39.1 bits (87), Expect = 0.14 Identities = 28/99 (28%), Positives = 46/99 (46%), Gaps = 2/99 (2%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638 +PG ID H+H ++PG + F + T + AMP TN +VD + + + Sbjct: 54 IPGAIDTHIHFQDPGRIYREDFEHATAACACGGITTGM-AMPTTN--LVDVEGYKFNTQT 110 Query: 637 ARVSARCDYALYVGASSTNYDTICELAPQA--AALKMYL 527 DYAL+ +N D + +L Q A+KM++ Sbjct: 111 YEGRGYIDYALHGAGRPSNVDQVEDLWTQTGITAIKMFM 149 Score = 38.3 bits (85), Expect = 0.24 Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 7/75 (9%) Frame = -1 Query: 222 PVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE-----NPPPGYPGLETILPLL 64 PV+ +++ ++W + IDV +DH P EK G PGLE LP L Sbjct: 280 PVMRGEDNRLKMWELLEKGYIDVIGSDHCPAEKWEKEVALNDIWKTHYGIPGLEVYLPSL 339 Query: 63 LNAVHQGRLTIEDLL 19 L+ V++G +++E ++ Sbjct: 340 LDGVNKGLVSLEKVV 354 >UniRef50_Q6BV31 Cluster: Similar to CA5801|CaDAL1 Candida albicans CaDAL1 allantoinase; n=2; Saccharomycetaceae|Rep: Similar to CA5801|CaDAL1 Candida albicans CaDAL1 allantoinase - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 648 Score = 39.1 bits (87), Expect = 0.14 Identities = 16/42 (38%), Positives = 27/42 (64%) Frame = -2 Query: 380 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 P+HI H+A E I +++AAK + + ++ E C H+L L + I Sbjct: 426 PLHIVHLATHEAIPLVRAAKAQNLPISAETCFHYLSLAAEKI 467 >UniRef50_P40757 Cluster: Allantoinase, mitochondrial precursor; n=1; Rana catesbeiana|Rep: Allantoinase, mitochondrial precursor - Rana catesbeiana (Bull frog) Length = 484 Score = 39.1 bits (87), Expect = 0.14 Identities = 28/84 (33%), Positives = 41/84 (48%), Gaps = 3/84 (3%) Frame = -2 Query: 497 DMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDR---PVHICHVARKEEILIIKA 327 D T++Q S P M + AAV L+A L + HI H++ + + II+ Sbjct: 213 DSTLYQTFLDSRPDDMEI---------AAVQLVADLCQQYKVRCHIVHLSSAQSLTIIRK 263 Query: 326 AKERGVKVTCEVCPHHLFLNSNDI 255 AKE G +T E H+L L+S I Sbjct: 264 AKEAGAPLTVETTHHYLSLSSEHI 287 >UniRef50_Q84FR6 Cluster: D-hydantoinase; n=1; Arthrobacter crystallopoietes|Rep: D-hydantoinase - Arthrobacter crystallopoietes Length = 457 Score = 38.7 bits (86), Expect = 0.18 Identities = 27/79 (34%), Positives = 41/79 (51%), Gaps = 9/79 (11%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK------NSENPPPGYPGLE 82 +A + P L + E Q LWR I+ + V ++DH P EEK + P G PG+E Sbjct: 286 KAVLTPPLRTQEHQDALWRGINTGALSVVSSDHCPFCFEEKQRMGADDFRQIPNGGPGVE 345 Query: 81 -TILPLLLNAVHQGRLTIE 28 +L + V +G++TIE Sbjct: 346 HRMLVMYETGVAEGKMTIE 364 >UniRef50_A6CCA9 Cluster: Dihydroorotase, multifunctional complex type; n=1; Planctomyces maris DSM 8797|Rep: Dihydroorotase, multifunctional complex type - Planctomyces maris DSM 8797 Length = 426 Score = 38.7 bits (86), Expect = 0.18 Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 5/79 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64 KV P L S E L + ID +DH PH E+K E G GLET+LP+ Sbjct: 276 KVLPPLRSQEHIDALIEGLKDGTIDAICSDHTPHAAEKKTDEILGADFGIIGLETLLPVC 335 Query: 63 LNA-VHQGRLTIEDLLCRI 10 L + + G L+ +L+ ++ Sbjct: 336 LQSLITPGHLSWPELIGKL 354 Score = 37.9 bits (84), Expect = 0.31 Identities = 23/84 (27%), Positives = 44/84 (52%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 ++ PGFID+HV + EPG + + +T + +PNT+P + DR++ ++ Sbjct: 50 LIVSPGFIDIHVSLCEPGFE-EDETIESGTAAALAGGVTSLGCLPNTSPVVDDRSSAEFI 108 Query: 646 STLARVSARCDYALYVGASSTNYD 575 A +A C + +GA + N++ Sbjct: 109 LLQAERAANC-HVYPLGAITKNHE 131 Score = 35.9 bits (79), Expect = 1.3 Identities = 15/46 (32%), Positives = 27/46 (58%) Frame = -2 Query: 407 ILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFL 270 I +A L +H+ ++ + + I+ AK G++V+ +V PHHL L Sbjct: 218 IALAELTRGRIHLMCISTQNSVSQIRRAKAAGIRVSADVTPHHLTL 263 >UniRef50_Q972W9 Cluster: 413aa long hypothetical D-hydantoinase; n=1; Sulfolobus tokodaii|Rep: 413aa long hypothetical D-hydantoinase - Sulfolobus tokodaii Length = 413 Score = 38.7 bits (86), Expect = 0.18 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 4/51 (7%) Frame = -1 Query: 201 DQAELWRNISIIDVFATDH--APHTVEEKNSENPP--PGYPGLETILPLLL 61 D E+W+ I+ + + ATDH V+E + E P PG PG+E +P++L Sbjct: 264 DPEEIWKRINKVSIIATDHNWFDKEVKENHKEFPDLVPGLPGVELRVPIIL 314 >UniRef50_P32375 Cluster: Allantoinase; n=3; Saccharomycetaceae|Rep: Allantoinase - Saccharomyces cerevisiae (Baker's yeast) Length = 460 Score = 38.7 bits (86), Expect = 0.18 Identities = 17/42 (40%), Positives = 26/42 (61%) Frame = -2 Query: 380 PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 PVHI H+A + I +I+ A+ G+ VT E C H+L + + I Sbjct: 245 PVHIVHLASMKAIPLIRKARASGLPVTTETCFHYLCIAAEQI 286 >UniRef50_Q5NPE4 Cluster: Dihydroorotase; n=8; Sphingomonadales|Rep: Dihydroorotase - Zymomonas mobilis Length = 408 Score = 38.3 bits (85), Expect = 0.24 Identities = 25/77 (32%), Positives = 39/77 (50%), Gaps = 5/77 (6%) Frame = -1 Query: 234 AKVCPVLCSPEDQ---AELWRNISIIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILP 70 A++ P L +D+ E R+ +ID+F + H P E+K + PG G ET+L Sbjct: 262 ARLSPPLRGEDDRLASVEALRD-GVIDMFCSAHDPRDAEDKRLPFIDAKPGMAGAETLLS 320 Query: 69 LLLNAVHQGRLTIEDLL 19 L VHQG + + L+ Sbjct: 321 ASLELVHQGVIDLSRLV 337 Score = 35.1 bits (77), Expect = 2.2 Identities = 18/56 (32%), Positives = 30/56 (53%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267 AE A +++A +H + K+ +I+ AKE+GVKVT + P +L L+ Sbjct: 196 AEAIVVARDLMLAEETGCKIHFAQLTTKKSFDLIRQAKEKGVKVTVGINPAYLLLS 251 >UniRef50_Q31EK1 Cluster: Aspartate carbamoyltransferase, non-catalytic chain; n=1; Thiomicrospira crunogena XCL-2|Rep: Aspartate carbamoyltransferase, non-catalytic chain - Thiomicrospira crunogena (strain XCL-2) Length = 428 Score = 38.3 bits (85), Expect = 0.24 Identities = 19/60 (31%), Positives = 30/60 (50%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE A +++A VH ++ + +I AK+RG+ VTC+V H L L D+ Sbjct: 211 AETAALARDLILAEETGARVHFSQISTARSLEMIADAKKRGMPVTCDVAIHQLHLTEYDV 270 Score = 37.1 bits (82), Expect = 0.55 Identities = 25/70 (35%), Positives = 34/70 (48%), Gaps = 4/70 (5%) Frame = -1 Query: 228 VCPVLCSPEDQAELWRNIS--IIDVFATDHAP--HTVEEKNSENPPPGYPGLETILPLLL 61 V P L + +D+ L + IID +DH P V+ PG GLET+LPL L Sbjct: 279 VTPPLRTHDDKEALRLGVKMGIIDAIVSDHTPLDRDVKLLPFGESEPGISGLETLLPLTL 338 Query: 60 NAVHQGRLTI 31 V +G L + Sbjct: 339 RLVEEGVLDL 348 Score = 36.3 bits (80), Expect = 0.96 Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 2/96 (2%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTAFDYAS 644 LPG +D+H + EPG+ +G ++ + V +T IC+ P+TNP + + Sbjct: 55 LPGLVDLHARLAEPGSRYEG---NIASETKAAVSGGITTICSPPDTNPVNDTQAVTELIQ 111 Query: 643 TLARVSARCDYALYVGASSTNYDTICELAPQAAALK 536 AR +A + L +GA + + ++ AALK Sbjct: 112 RRARQAATA-FVLPIGALTQGLEG--KMLSNMAALK 144 >UniRef50_A1A2Z8 Cluster: Putative allantoinase; n=3; Bifidobacterium adolescentis|Rep: Putative allantoinase - Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083) Length = 278 Score = 38.3 bits (85), Expect = 0.24 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Frame = -2 Query: 449 PVCTHAEREKTAA--VILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHL 276 P AE E A ++ + + HI HV+ + +++ AK G+ V+ E CPH+L Sbjct: 46 PASRPAECEANAVRKIVRLVARTGCRTHILHVSSGLSVDVLRRAKAEGLPVSAETCPHYL 105 Query: 275 FLNSNDI 255 L+ + I Sbjct: 106 TLDCDHI 112 >UniRef50_Q2GR02 Cluster: Putative uncharacterized protein; n=4; Sordariomycetes|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 593 Score = 38.3 bits (85), Expect = 0.24 Identities = 18/53 (33%), Positives = 34/53 (64%), Gaps = 1/53 (1%) Frame = -2 Query: 410 VILMASLLDR-PVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 ++ MA L + +HI H++ E + I++ A++ G+ +T E C H+L L S++I Sbjct: 253 ILSMAHLAPQLHLHIVHLSATECVPILRKARQDGINITAETCFHYLGLASDNI 305 >UniRef50_Q31R01 Cluster: Dihydroorotase and related cyclic amidohydrolases-like; n=2; Synechococcus elongatus|Rep: Dihydroorotase and related cyclic amidohydrolases-like - Synechococcus sp. (strain PCC 7942) (Anacystis nidulans R2) Length = 411 Score = 37.9 bits (84), Expect = 0.31 Identities = 20/63 (31%), Positives = 35/63 (55%), Gaps = 3/63 (4%) Frame = -2 Query: 431 EREKTAAVILMASLLD---RPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261 + +TAA+ L+ LL P+H+ V+ + +I A++RG+ +T V HL N+ Sbjct: 204 QSSETAALALLLELLADCLTPIHLMRVSTARSVELIAQAQQRGLPITASVTWLHLLGNTA 263 Query: 260 DIT 252 D+T Sbjct: 264 DLT 266 Score = 36.3 bits (80), Expect = 0.96 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 4/60 (6%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLL 64 ++ P L PE+Q L + + +I A DH+P+ EEK P G GLE LP L Sbjct: 273 RLAPPLPEPEEQLALQQAVQEGVITAIAVDHSPYLYEEKTVAFGEAPAGAIGLELALPQL 332 >UniRef50_A5KJ64 Cluster: Putative uncharacterized protein; n=1; Ruminococcus torques ATCC 27756|Rep: Putative uncharacterized protein - Ruminococcus torques ATCC 27756 Length = 455 Score = 37.9 bits (84), Expect = 0.31 Identities = 24/82 (29%), Positives = 36/82 (43%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE E ++ +A D PV I +++ I A+E G V E CP +L LN Sbjct: 215 AEAEAVGRILKIAKCADVPVIIVNLSTAAGYREILKAREIGQTVYVETCPEYLLLNEEKY 274 Query: 254 TKLEKGEQKYVQYYVVLKTKQN 189 + +KYV + K K + Sbjct: 275 ALAAEEARKYVTVPPLRKQKNS 296 >UniRef50_Q259B7 Cluster: H0901F07.3 protein; n=12; Magnoliophyta|Rep: H0901F07.3 protein - Oryza sativa (Rice) Length = 497 Score = 37.9 bits (84), Expect = 0.31 Identities = 14/42 (33%), Positives = 28/42 (66%), Gaps = 1/42 (2%) Frame = -2 Query: 377 VHICHVA-RKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +HI H++ K + ++K AK+ G +V+ E CPH+L ++ ++ Sbjct: 280 IHIVHLSDAKTSLGLLKDAKQNGARVSVETCPHYLAFSAEEV 321 >UniRef50_Q5PR45 Cluster: Zgc:103559; n=8; Eumetazoa|Rep: Zgc:103559 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 459 Score = 37.5 bits (83), Expect = 0.41 Identities = 16/40 (40%), Positives = 26/40 (65%) Frame = -2 Query: 374 HICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 HI H++ E + +I+AAK+ G +T E H+L L++ DI Sbjct: 238 HIVHLSSAEPLELIRAAKQAGAPLTVETTHHYLNLSAEDI 277 >UniRef50_Q8EW20 Cluster: Dihydroorotase; n=1; Mycoplasma penetrans|Rep: Dihydroorotase - Mycoplasma penetrans Length = 422 Score = 37.5 bits (83), Expect = 0.41 Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 3/55 (5%) Frame = -1 Query: 168 IDVFATDHAPHTVEEKNSENPPPGYPGLETILPLLLNAVHQGRLTI---EDLLCR 13 ID+ +DH P ++ EK E G P ET+ +L ++ + R+ I EDLLC+ Sbjct: 272 IDIITSDHTPVSLIEK-FETEQKGLPNFETMFSILFDSCYYKRIPITILEDLLCK 325 >UniRef50_A3DM45 Cluster: Amidohydrolase; n=1; Staphylothermus marinus F1|Rep: Amidohydrolase - Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / F1) Length = 430 Score = 37.5 bits (83), Expect = 0.41 Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 2/51 (3%) Frame = -1 Query: 168 IDVFATDHAPHTVEEKN--SENPPPGYPGLETILPLLLNAVHQGRLTIEDL 22 ID A+DHAPH+V EK + PPG G+E I + V +G ++++ + Sbjct: 287 IDALASDHAPHSVVEKMCCPKTCPPGINGVEVISVFAGDLVSKGIISLDQM 337 Score = 36.3 bits (80), Expect = 0.96 Identities = 21/84 (25%), Positives = 40/84 (47%) Frame = -3 Query: 826 IVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYA 647 ++ PGFID+HVH+R+ + K + + +T++ MPNT P I + + + Sbjct: 53 VIAFPGFIDMHVHLRDFKQSYKETI-ETGTKAALHGGITVVGEMPNTLPRIDNFSILEKR 111 Query: 646 STLARVSARCDYALYVGASSTNYD 575 + ++ DY +Y+ D Sbjct: 112 MKILENNSYTDYYVYIDVPENKSD 135 >UniRef50_Q8G657 Cluster: Dihydroorotase; n=4; Bifidobacterium|Rep: Dihydroorotase - Bifidobacterium longum Length = 498 Score = 37.1 bits (82), Expect = 0.55 Identities = 16/43 (37%), Positives = 23/43 (53%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITK 249 VH HV+ I+ AK G+ +TCE PH+L L+ + K Sbjct: 258 VHFQHVSTAISFEAIRRAKAEGLPITCETAPHYLALSDEALLK 300 Score = 34.3 bits (75), Expect = 3.9 Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 4/55 (7%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLE 82 AK+ P L S D+ I+ +D+ ATDHAPHT+ EK P G GLE Sbjct: 305 AKMNPPLRSEADRKATIAAIADGTVDLLATDHAPHTLAEKELGFLEAPNGIIGLE 359 >UniRef50_A6NQ76 Cluster: Putative uncharacterized protein; n=1; Bacteroides capillosus ATCC 29799|Rep: Putative uncharacterized protein - Bacteroides capillosus ATCC 29799 Length = 472 Score = 37.1 bits (82), Expect = 0.55 Identities = 16/57 (28%), Positives = 30/57 (52%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261 E E + ++ + PV++ H++ + +I+AA+ RG K E CP + LN + Sbjct: 228 EAEAVNRWLALSEMAGYPVNVVHLSTLRGLEVIRAARARGQKCYVESCPQYFLLNED 284 >UniRef50_A6G7W0 Cluster: Dihydroorotase and related cyclic amidoHydrolase; n=1; Plesiocystis pacifica SIR-1|Rep: Dihydroorotase and related cyclic amidoHydrolase - Plesiocystis pacifica SIR-1 Length = 438 Score = 37.1 bits (82), Expect = 0.55 Identities = 16/41 (39%), Positives = 24/41 (58%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 VHI H++ I +I A+ G+ V+ E CPH+L L + I Sbjct: 221 VHIVHLSAASAIPVIAQARAEGLGVSVETCPHYLSLAAESI 261 >UniRef50_Q9YFI5 Cluster: Dihydroorotase; n=1; Aeropyrum pernix|Rep: Dihydroorotase - Aeropyrum pernix Length = 425 Score = 37.1 bits (82), Expect = 0.55 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 2/98 (2%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLV-VLTMICAMPNTNPSIVDRTAFDYAST 641 LPG ID+HVH+R G + + ++ +T++ MPNT P + A Sbjct: 54 LPGVIDMHVHLR--GLKLSYKEDEVSGTAAAASGCVTLVADMPNTQPPLRTPEALREKLA 111 Query: 640 LARVSARCDYALYVGASSTNYDTICELAPQA-AALKMY 530 A+ DY +Y G +Y E+A A K+Y Sbjct: 112 SLEAGAKVDYTVYAGV-PRSYGEAVEMASMGIAGFKIY 148 Score = 34.7 bits (76), Expect = 2.9 Identities = 15/32 (46%), Positives = 21/32 (65%), Gaps = 2/32 (6%) Frame = -1 Query: 171 IIDVFATDHAPHTVEEK--NSENPPPGYPGLE 82 ++D A+DHAPH+ EK + PPG+P LE Sbjct: 286 LVDAIASDHAPHSTWEKWMHPAIAPPGFPWLE 317 >UniRef50_Q30S48 Cluster: Amidohydrolase; n=1; Thiomicrospira denitrificans ATCC 33889|Rep: Amidohydrolase - Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1351) Length = 399 Score = 36.7 bits (81), Expect = 0.72 Identities = 18/38 (47%), Positives = 23/38 (60%) Frame = -2 Query: 362 VARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDITK 249 +A I +I AK GV VTCEV HH+ LNS++ K Sbjct: 222 IASPRSIYLINKAKSEGVNVTCEVSIHHI-LNSDESCK 258 >UniRef50_Q08M50 Cluster: Allantoinase; n=1; Stigmatella aurantiaca DW4/3-1|Rep: Allantoinase - Stigmatella aurantiaca DW4/3-1 Length = 311 Score = 36.7 bits (81), Expect = 0.72 Identities = 17/61 (27%), Positives = 31/61 (50%) Frame = -2 Query: 437 HAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 258 H E + ++ + L VHI H++ + + I AA+ G+ + E CPH+L ++ Sbjct: 73 HWEDDAIRMMVELCRLHRTRVHIVHLSSSDALPDIAAARREGLPFSVETCPHYLTFDAEH 132 Query: 257 I 255 I Sbjct: 133 I 133 >UniRef50_A5ZUT5 Cluster: Putative uncharacterized protein; n=1; Ruminococcus obeum ATCC 29174|Rep: Putative uncharacterized protein - Ruminococcus obeum ATCC 29174 Length = 457 Score = 36.7 bits (81), Expect = 0.72 Identities = 17/61 (27%), Positives = 30/61 (49%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 E E ++++A D PV + H+ K+ + A+ G +V E CP +L L+ + Sbjct: 216 EAEAVHRLLVIAKEADAPVMVVHLTNKKAFEEVMRARANGQEVYAETCPQYLLLDDSVYA 275 Query: 251 K 249 K Sbjct: 276 K 276 >UniRef50_Q1ERB5 Cluster: L-hydantoinase HyuH; n=1; uncultured crenarchaeote 31-F-01|Rep: L-hydantoinase HyuH - uncultured crenarchaeote 31-F-01 Length = 486 Score = 36.7 bits (81), Expect = 0.72 Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 26/99 (26%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEK------------NSENPPP 100 R KV P L S +D A +W IS +ID +DH + ++ K +S N Sbjct: 295 RGKVVPPLRSKDDVAMVWDAISNGLIDCIGSDHVANRLDMKLGSGSCGGSSIGSSSNDGD 354 Query: 99 G-----------YPGLETILPLLLN-AVHQGRLTIEDLL 19 G +PG+ TILP++L+ V++GR+T+E L+ Sbjct: 355 GSDGDVWSALAGFPGIATILPVMLSEGVNKGRITLERLV 393 >UniRef50_Q2KUT6 Cluster: Dihydroorotase precursor; n=1; Bordetella avium 197N|Rep: Dihydroorotase precursor - Bordetella avium (strain 197N) Length = 390 Score = 36.3 bits (80), Expect = 0.96 Identities = 13/41 (31%), Positives = 25/41 (60%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 +H+C ++ + +++AA+ G+ VT ++ HHL L DI Sbjct: 193 LHLCRLSSAAGVALLRAARAEGLPVTADISIHHLHLTDLDI 233 >UniRef50_A6LUW0 Cluster: Dihydropyrimidinase; n=1; Clostridium beijerinckii NCIMB 8052|Rep: Dihydropyrimidinase - Clostridium beijerinckii NCIMB 8052 Length = 458 Score = 36.3 bits (80), Expect = 0.96 Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Frame = -2 Query: 437 HAEREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVK-VTCEVCPHHLFLNS 264 H E E + V+ +A+L D P++I H++ ++ + I+ A+ +G K + E C +L + Sbjct: 212 HCEAEAISRVLHLAALAGDAPIYIVHISTEKGLDEIRKARAQGQKNIFSETCTQYLTMTE 271 Query: 263 NDITKLEKGEQKYV 222 + + KYV Sbjct: 272 KKYLEPDNNGLKYV 285 >UniRef50_Q97C35 Cluster: Dihydroorotase; n=2; Thermoplasma|Rep: Dihydroorotase - Thermoplasma volcanium Length = 415 Score = 36.3 bits (80), Expect = 0.96 Identities = 19/49 (38%), Positives = 30/49 (61%), Gaps = 1/49 (2%) Frame = -1 Query: 165 DVFATDHAPHTVEEK-NSENPPPGYPGLETILPLLLNAVHQGRLTIEDL 22 D+ ++DHAPHT ++K E G G+ET +PL+L V + L ++ L Sbjct: 273 DILSSDHAPHTEKDKAEFEYAKSGIIGVETRIPLMLALVKKKILFLDVL 321 Score = 33.5 bits (73), Expect = 6.8 Identities = 29/97 (29%), Positives = 42/97 (43%) Frame = -3 Query: 817 LPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVVLTMICAMPNTNPSIVDRTAFDYASTL 638 LP D+HVH R PG K F T++ MPN I D AF + Sbjct: 47 LPAATDIHVHFRTPGETDKEDF-STGSLSAIFGGTTLVMDMPNNIIPIKDYNAFSDKLGV 105 Query: 637 ARVSARCDYALYVGASSTNYDTICELAPQAAALKMYL 527 ++ D+ALY + +N I + ++ LK+YL Sbjct: 106 INGTSYSDFALYSMETGSN-SLIVD--SRSIGLKVYL 139 >UniRef50_Q4T977 Cluster: Chromosome undetermined SCAF7631, whole genome shotgun sequence; n=9; Euteleostomi|Rep: Chromosome undetermined SCAF7631, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 258 Score = 35.9 bits (79), Expect = 1.3 Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 2/52 (3%) Frame = -1 Query: 258 HYKIGKGRAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSEN 109 H G + K CP + +QA+LW + ID+ +DH+P T + KN E+ Sbjct: 74 HIPAGATQFKCCPPIRDSINQAQLWSALKAGHIDMVVSDHSPCTPDLKNLES 125 >UniRef50_Q7WMP7 Cluster: Dihydroorotase-like protein; n=3; Bordetella|Rep: Dihydroorotase-like protein - Bordetella bronchiseptica (Alcaligenes bronchisepticus) Length = 457 Score = 35.9 bits (79), Expect = 1.3 Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 5/77 (6%) Frame = -1 Query: 234 AKVCPVLCSPEDQAELWRNI--SIIDVFATDHAPH--TVEEKNSENPPPGYPGLETILPL 67 AKV P + S D +W + I +DH P ++K+ G+PG ILP+ Sbjct: 288 AKVNPPVRSAADIDAMWEGVCDGAITTIGSDHVPRKRATKDKDIWAASNGFPGTGMILPI 347 Query: 66 LLN-AVHQGRLTIEDLL 19 LL+ H+ ++ +E L+ Sbjct: 348 LLHEGYHRRQVPLETLM 364 Score = 35.5 bits (78), Expect = 1.7 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 2/69 (2%) Frame = -2 Query: 467 SWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERG--VKVTCE 294 +W ++ P E E V A PV+I H++ +E + ++ + G + E Sbjct: 213 AWNEQSP--DFLEAENVHRVCYFAGKTGTPVNIVHLSSREALREVRRHRHEGRAAPIYVE 270 Query: 293 VCPHHLFLN 267 CPH+LFL+ Sbjct: 271 TCPHYLFLD 279 >UniRef50_Q47RB7 Cluster: Allantoinase; n=1; Thermobifida fusca YX|Rep: Allantoinase - Thermobifida fusca (strain YX) Length = 474 Score = 35.9 bits (79), Expect = 1.3 Identities = 19/60 (31%), Positives = 29/60 (48%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AER V+ A VHI E I+ AA++ G+ V+ + CPH+L L + + Sbjct: 254 AERRGLERVLAAARSSGARVHISPFVAAECAAILAAARDIGIPVSAQTCPHYLCLPAEHV 313 >UniRef50_A4CLI6 Cluster: Dihydroorotase, multifunctional complex type; n=3; Flavobacteriaceae|Rep: Dihydroorotase, multifunctional complex type - Robiginitalea biformata HTCC2501 Length = 417 Score = 35.9 bits (79), Expect = 1.3 Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPPPGYP--GLETILPLL 64 KV P L + +D+ L + ++ IID TDH P +EEK E Y GLE+ +L Sbjct: 278 KVLPPLRTKKDRKALQKALAENIIDFVTTDHNPMDIEEKRQEFDRAAYGTLGLESAFGIL 337 Query: 63 LNAVHQGRLTIEDLLCRIR 7 R D LCR R Sbjct: 338 NKLFGTDRAV--DFLCRGR 354 >UniRef50_A0K2C1 Cluster: Dihydropyrimidinase; n=1; Arthrobacter sp. FB24|Rep: Dihydropyrimidinase - Arthrobacter sp. (strain FB24) Length = 479 Score = 35.9 bits (79), Expect = 1.3 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 7/76 (9%) Frame = -1 Query: 225 CPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENP-----PPGYPGLETILPL 67 CP + SPE A L ++ I ++DH+ + + +K P G PG+ET +P+ Sbjct: 291 CPPMRSPETVAALKERLADGAIHTVSSDHSCYDLSQKRERTDDIRAMPHGLPGVETRMPV 350 Query: 66 LLNAVHQGRLTIEDLL 19 A+ ++ED + Sbjct: 351 TFTAMASAGSSVEDFV 366 Score = 34.7 bits (76), Expect = 2.9 Identities = 16/56 (28%), Positives = 26/56 (46%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLN 267 AE + MA PV+ H + + ++ A+ RG + E CPH+L L+ Sbjct: 221 AEEISVKETLAMAEYTKAPVYFVHQSTPGAVDLVTEARARGQEAFSETCPHYLTLD 276 >UniRef50_Q972L4 Cluster: 464aa long hypothetical D-hydantoinase; n=1; Sulfolobus tokodaii|Rep: 464aa long hypothetical D-hydantoinase - Sulfolobus tokodaii Length = 464 Score = 35.9 bits (79), Expect = 1.3 Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 10/68 (14%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNISIIDVFA--TDHAPHTVEEKNS--ENPPP------GYPG 88 R + P L S E + +LW ++ D+F +DH ++ +K E PP G PG Sbjct: 285 RYVMSPPLRSDEQRTKLWMRLASGDIFTVGSDHCVYSDAQKKRYREEVPPFHEIPNGVPG 344 Query: 87 LETILPLL 64 ETILP+L Sbjct: 345 TETILPIL 352 >UniRef50_Q7UNR2 Cluster: Putative dihydroorotase; n=1; Pirellula sp.|Rep: Putative dihydroorotase - Rhodopirellula baltica Length = 456 Score = 35.9 bits (79), Expect = 1.3 Identities = 18/56 (32%), Positives = 28/56 (50%) Frame = -2 Query: 440 THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLF 273 T AE A + +A +H+ V+ I +I K RG+ ++ VCPH+LF Sbjct: 230 TEAEDLAVARDVRLAEATKGRLHVGPVSTMGSIDMIGRVKSRGIHISASVCPHNLF 285 >UniRef50_Q59699 Cluster: D-hydantoinase; n=11; Proteobacteria|Rep: D-hydantoinase - Pseudomonas putida Length = 495 Score = 35.9 bits (79), Expect = 1.3 Identities = 17/60 (28%), Positives = 32/60 (53%) Frame = -2 Query: 440 THAEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261 + E E + I +A + P+++ H++ +E + I A+ +G V EV P HL L+ + Sbjct: 214 SQVEGEAASRAIRIAETIGTPLYVVHISSREALDEITYARAKGQPVYGEVLPGHLLLDDS 273 >UniRef50_Q1AZI1 Cluster: D-hydantoinase; n=1; Rubrobacter xylanophilus DSM 9941|Rep: D-hydantoinase - Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129) Length = 467 Score = 35.5 bits (78), Expect = 1.7 Identities = 22/70 (31%), Positives = 33/70 (47%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 E E T I +A + P+ + HV+ + I A E G V E CP +L L+ +D+ Sbjct: 218 EAEATNRAIQLAEVAGCPLLVVHVSCAAALEEIHRAHELGQTVYAETCPQYLALSYDDLC 277 Query: 251 KLEKGEQKYV 222 + KYV Sbjct: 278 REGFEGAKYV 287 >UniRef50_Q0VTM6 Cluster: Dihydroorotase, multifunctional complex type; n=1; Alcanivorax borkumensis SK2|Rep: Dihydroorotase, multifunctional complex type - Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM 11573) Length = 443 Score = 35.5 bits (78), Expect = 1.7 Identities = 23/70 (32%), Positives = 34/70 (48%), Gaps = 4/70 (5%) Frame = -1 Query: 228 VCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSENPP--PGYPGLETILPLLL 61 V P L S ED+ L ++ ID + H P K + P PG GL+ +L L+L Sbjct: 297 VIPPLRSAEDRQALLEAVADGTIDAICSQHTPIGSSSKAAPFPTTKPGMAGLDVLLSLVL 356 Query: 60 NAVHQGRLTI 31 V +G+L + Sbjct: 357 QLVDEGKLDL 366 Score = 34.3 bits (75), Expect = 3.9 Identities = 16/58 (27%), Positives = 30/58 (51%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261 AE + +L+ H ++ ++ + ++KAAK RG+ VT +V HL L+ + Sbjct: 229 AESVDLSRDLLLVEATGVRAHFQQISSRDSLRLLKAAKRRGLPVTADVSIQHLLLDES 286 >UniRef50_A6VSQ0 Cluster: Dihydroorotase, multifunctional complex type; n=4; Gammaproteobacteria|Rep: Dihydroorotase, multifunctional complex type - Marinomonas sp. MWYL1 Length = 425 Score = 35.5 bits (78), Expect = 1.7 Identities = 24/78 (30%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Frame = -1 Query: 240 GRAKVCPVLCSPEDQAELWRNIS--IIDVFATDHAPHTVEEKNSE--NPPPGYPGLETIL 73 G V P L S ED+ L I +I +DH PH K + PG +E +L Sbjct: 274 GHFHVLPPLRSDEDRLTLIEGIKAGVISAICSDHQPHEKMAKIAPFAATEPGMANVEILL 333 Query: 72 PLLLNAVHQGRLTIEDLL 19 PL + + +G L +L Sbjct: 334 PLAMQLMDEGDLDFSTVL 351 >UniRef50_A3HYA6 Cluster: Dihydroorotase and related cyclic amidohydrolase; n=1; Algoriphagus sp. PR1|Rep: Dihydroorotase and related cyclic amidohydrolase - Algoriphagus sp. PR1 Length = 413 Score = 35.5 bits (78), Expect = 1.7 Identities = 14/41 (34%), Positives = 24/41 (58%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 VH ++ + + +I+ AKE G+ VTC+V + L ND+ Sbjct: 227 VHFQTISSAKAVSLIRQAKEEGLNVTCDVSIYQLLFTDNDL 267 >UniRef50_A4R534 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 297 Score = 35.5 bits (78), Expect = 1.7 Identities = 18/55 (32%), Positives = 32/55 (58%), Gaps = 1/55 (1%) Frame = -2 Query: 521 NFYNFLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPV-HICHV 360 ++YN L + W+K FQ+WP+K+ V +HA + K V S + P+ H+ ++ Sbjct: 127 SYYNVLFAIIAFWRK-FQTWPEKLTVVSHAFK-KARIVEAHCSAIGFPIEHVNYI 179 >UniRef50_Q972X8 Cluster: 433aa long hypothetical D-hydantoinase; n=1; Sulfolobus tokodaii|Rep: 433aa long hypothetical D-hydantoinase - Sulfolobus tokodaii Length = 433 Score = 35.5 bits (78), Expect = 1.7 Identities = 15/57 (26%), Positives = 28/57 (49%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSN 261 E E ++A L +I H++ + II +++G K+ E CPH+L + + Sbjct: 210 EEEAVNRASMLAYLTGAKTYIVHISSPTSLDIISYWRKKGAKIFSETCPHYLLFDDS 266 >UniRef50_Q45515 Cluster: D-hydantoinase; n=14; Bacteria|Rep: D-hydantoinase - Bacillus stearothermophilus (Geobacillus stearothermophilus) Length = 471 Score = 35.5 bits (78), Expect = 1.7 Identities = 19/70 (27%), Positives = 33/70 (47%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDIT 252 E E T + L +++ HV+ + + I A+ +G+ V E CP +L L+ + + Sbjct: 217 EGEATGRACQLTELAGSQLYVVHVSCAQAVEKIAEARNKGLNVWGETCPQYLVLDQSYLE 276 Query: 251 KLEKGEQKYV 222 K KYV Sbjct: 277 KPNFEGAKYV 286 >UniRef50_UPI00015B49FE Cluster: PREDICTED: similar to alpha-glucosidase isozyme I; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to alpha-glucosidase isozyme I - Nasonia vitripennis Length = 590 Score = 35.1 bits (77), Expect = 2.2 Identities = 16/49 (32%), Positives = 25/49 (51%) Frame = -2 Query: 338 IIKAAKERGVKVTCEVCPHHLFLNSNDITKLEKGEQKYVQYYVVLKTKQ 192 + K AKE G+K+ ++ P+H KG KY QYY+ + K+ Sbjct: 105 LTKKAKELGIKIIMDLVPNHTSDKHQWFVDSLKGNTKYAQYYIWREGKE 153 >UniRef50_A6WFZ1 Cluster: Dihydropyrimidinase; n=1; Kineococcus radiotolerans SRS30216|Rep: Dihydropyrimidinase - Kineococcus radiotolerans SRS30216 Length = 472 Score = 35.1 bits (77), Expect = 2.2 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 1/59 (1%) Frame = -2 Query: 431 EREKTAAVILMASLL-DRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 258 E E I +A + D P+++ HV+ + I +A+ G V E CP +L+L D Sbjct: 221 EGEAVNRAIALAEVAGDTPLYVVHVSSSPALDRIASARSEGRNVFAETCPQYLYLTLED 279 >UniRef50_A5GXS3 Cluster: Faciata 1-like protein; n=6; Poaceae|Rep: Faciata 1-like protein - Zea mays (Maize) Length = 348 Score = 35.1 bits (77), Expect = 2.2 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 5/63 (7%) Frame = -1 Query: 174 SIIDVFATDHAPHTVEEKNSENPPPGYPGL-----ETILPLLLNAVHQGRLTIEDLLCRI 10 +++DV TD + TVEE N NP G PG ET LP ++ + R I ++ + Sbjct: 187 AVVDVPLTDSSSATVEEINQPNPKDGSPGAASAIPETDLPEIVQVIRSCRDGIHKVVELL 246 Query: 9 RHE 1 +H+ Sbjct: 247 QHK 249 >UniRef50_Q2LWS0 Cluster: DNA polymerase III, delta subunit; n=1; Syntrophus aciditrophicus SB|Rep: DNA polymerase III, delta subunit - Syntrophus aciditrophicus (strain SB) Length = 460 Score = 34.7 bits (76), Expect = 2.9 Identities = 26/85 (30%), Positives = 41/85 (48%) Frame = -1 Query: 255 YKIGKGRAKVCPVLCSPEDQAELWRNISIIDVFATDHAPHTVEEKNSENPPPGYPGLETI 76 Y+I K+ L SPEDQA N+ ++D D P + E + PP PG + Sbjct: 36 YEISDAFTKIIDALLSPEDQA---LNLFVLD--GEDEDPERIGE--NLMTPPLLPG-RKV 87 Query: 75 LPLLLNAVHQGRLTIEDLLCRIRHE 1 + + + R T++DL+ RIR + Sbjct: 88 VAVRRTQLFSSRKTLKDLVKRIREQ 112 >UniRef50_A3PPE1 Cluster: Dihydropyrimidinase; n=3; Rhodobacter sphaeroides|Rep: Dihydropyrimidinase - Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) Length = 485 Score = 34.7 bits (76), Expect = 2.9 Identities = 19/71 (26%), Positives = 32/71 (45%) Frame = -2 Query: 434 AEREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 AE E I +A L+ + I HV+ E ++ A+ G+ + E CP +L D+ Sbjct: 217 AEAEAINRAISLARLVGAGLFIVHVSTPEGADLVARAQASGLPIHAETCPQYLAFTRADL 276 Query: 254 TKLEKGEQKYV 222 + KY+ Sbjct: 277 DRPGMEGAKYI 287 >UniRef50_Q7JZT9 Cluster: RE13129p; n=5; Diptera|Rep: RE13129p - Drosophila melanogaster (Fruit fly) Length = 492 Score = 34.7 bits (76), Expect = 2.9 Identities = 12/43 (27%), Positives = 26/43 (60%) Frame = -2 Query: 383 RPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 R +HI + + E + +++ + +G +T + CPH+L L + D+ Sbjct: 255 RCIHILNCSSGESLPLVEECRRQGGNLTVDTCPHYLALAAEDV 297 >UniRef50_Q11EY4 Cluster: Dihydropyrimidinase; n=25; Proteobacteria|Rep: Dihydropyrimidinase - Mesorhizobium sp. (strain BNC1) Length = 485 Score = 34.3 bits (75), Expect = 3.9 Identities = 23/84 (27%), Positives = 43/84 (51%) Frame = -2 Query: 509 FLLEDMTIWQKHFQSWPKKMPVCTHAEREKTAAVILMASLLDRPVHICHVARKEEILIIK 330 +L E M+ + H S P ++ E E T I++A PV+I H + ++ I+ Sbjct: 193 YLQEGMSGPEAHAYSRPPEV------EGEATNRAIMIADAAGVPVYIVHTSCEQSHEAIR 246 Query: 329 AAKERGVKVTCEVCPHHLFLNSND 258 A+++G++V E HL L+ ++ Sbjct: 247 RARQKGMRVYGEPLIQHLLLDESE 270 Score = 34.3 bits (75), Expect = 3.9 Identities = 27/76 (35%), Positives = 34/76 (44%), Gaps = 8/76 (10%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEK-----NSENPPPGYPGLET 79 R + P Q LW ++ + V ATDHA T E+K + P G GLE Sbjct: 281 RRVMSPPFRDKRHQDSLWAGLAAGSLQVVATDHAAFTTEQKRLGLNDFTKIPNGTGGLED 340 Query: 78 ILPLLLN-AVHQGRLT 34 +PLL V GRLT Sbjct: 341 RMPLLWTYGVKTGRLT 356 >UniRef50_Q0BZU5 Cluster: Putative dihydroorotase; n=1; Hyphomonas neptunium ATCC 15444|Rep: Putative dihydroorotase - Hyphomonas neptunium (strain ATCC 15444) Length = 426 Score = 34.3 bits (75), Expect = 3.9 Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 2/55 (3%) Frame = -1 Query: 168 IDVFATDHAPHTVEEKNSE--NPPPGYPGLETILPLLLNAVHQGRLTIEDLLCRI 10 ID + H P EEK G GLET+L LLN H G LT+ + L + Sbjct: 302 IDAVVSAHDPQPPEEKRLPFGEAAFGAAGLETVLSALLNLHHDGPLTLLEALAPV 356 >UniRef50_A3UJX0 Cluster: Aspartate transcarbamoylase, pyrC' subunit; n=1; Oceanicaulis alexandrii HTCC2633|Rep: Aspartate transcarbamoylase, pyrC' subunit - Oceanicaulis alexandrii HTCC2633 Length = 421 Score = 34.3 bits (75), Expect = 3.9 Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 4/77 (5%) Frame = -1 Query: 237 RAKVCPVLCSPEDQAELWRNISI--IDVFATDHAPHTVEEKNSENPP--PGYPGLETILP 70 R ++ P L S D+ L +S ID +DH T E K P PG LE +LP Sbjct: 270 RYRLEPPLRSENDRQALIDALSDGRIDAVVSDHIALTNESKAHPFPEAAPGSATLEALLP 329 Query: 69 LLLNAVHQGRLTIEDLL 19 +L +GR+++ + L Sbjct: 330 VLCGLAEEGRMSLAEAL 346 >UniRef50_UPI0001554813 Cluster: PREDICTED: hypothetical protein; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: hypothetical protein - Ornithorhynchus anatinus Length = 554 Score = 33.9 bits (74), Expect = 5.1 Identities = 11/20 (55%), Positives = 16/20 (80%) Frame = -3 Query: 832 GNIVKLPGFIDVHVHVREPG 773 G++V +PG +D HVH+ EPG Sbjct: 76 GDLVVMPGVVDCHVHINEPG 95 >UniRef50_Q12EE5 Cluster: Allantoinase; n=57; Betaproteobacteria|Rep: Allantoinase - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 446 Score = 33.9 bits (74), Expect = 5.1 Identities = 14/41 (34%), Positives = 23/41 (56%) Frame = -2 Query: 377 VHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSNDI 255 VH+C ++ + ++ AK G+ VTC+V + L L DI Sbjct: 242 VHLCRISSAAGVALVGKAKAEGLDVTCDVSINSLHLTDVDI 282 >UniRef50_A3ZYR8 Cluster: Dihydroorotase; n=1; Blastopirellula marina DSM 3645|Rep: Dihydroorotase - Blastopirellula marina DSM 3645 Length = 422 Score = 33.9 bits (74), Expect = 5.1 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 2/84 (2%) Frame = -3 Query: 832 GNIVKLPGFIDVHVHVREPGANIKGRF*DLLPQXHWLVV--LTMICAMPNTNPSIVDRTA 659 G IV PG ID+HV +REPG + +V T I +PNT P + + Sbjct: 49 GKIVA-PGLIDMHVQLREPGWEEDE---TIASGAAAAIVGGFTSIACIPNTEPPLDSPAS 104 Query: 658 FDYASTLARVSARCDYALYVGASS 587 +Y A + +C+ + ASS Sbjct: 105 IEYVRHKAARADKCNVFVIACASS 128 >UniRef50_Q18IV3 Cluster: Dihydroorotase; n=1; Haloquadratum walsbyi DSM 16790|Rep: Dihydroorotase - Haloquadratum walsbyi (strain DSM 16790) Length = 474 Score = 33.9 bits (74), Expect = 5.1 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 12/83 (14%) Frame = -1 Query: 231 KVCPVLCSPEDQAELWRNI--SIIDVFATDHAPH--TVEEKNS-------ENPPPGYPGL 85 K+ P L + + +LW + +ID TDH PH + +EK+ E P G+ Sbjct: 293 KISPPLRGEQSRQKLWHGLRDGVIDYAGTDHCPHKKSFKEKDEGKFGDIWEAIPGDNNGI 352 Query: 84 ETILPLLLN-AVHQGRLTIEDLL 19 E LP++++ V++ +++E L+ Sbjct: 353 EYFLPVMMSEGVNKNNISMERLV 375 >UniRef50_Q8YF78 Cluster: D-HYDANTOINASE; n=41; Proteobacteria|Rep: D-HYDANTOINASE - Brucella melitensis Length = 489 Score = 33.5 bits (73), Expect = 6.8 Identities = 16/58 (27%), Positives = 33/58 (56%) Frame = -2 Query: 431 EREKTAAVILMASLLDRPVHICHVARKEEILIIKAAKERGVKVTCEVCPHHLFLNSND 258 E E T I++A P+++ HV+ ++ I+ A+++G++V E HL L+ ++ Sbjct: 218 EGEATNRAIMIADQAGVPLYVVHVSCEQSHEAIRRARQKGIRVFGEPLIQHLTLDESE 275 >UniRef50_P72934 Cluster: Probable dihydroorotase-like protein; n=1; Synechocystis sp. PCC 6803|Rep: Probable dihydroorotase-like protein - Synechocystis sp. (strain PCC 6803) Length = 441 Score = 33.5 bits (73), Expect = 6.8 Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 2/38 (5%) Frame = -1 Query: 171 IIDVFATDHAPHTVEEKNS--ENPPPGYPGLETILPLL 64 +ID A DH T EEK PPG G E +LP L Sbjct: 329 VIDAIAVDHQAFTYEEKTQTFAETPPGAIGYELVLPCL 366 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 806,311,785 Number of Sequences: 1657284 Number of extensions: 15715575 Number of successful extensions: 39082 Number of sequences better than 10.0: 208 Number of HSP's better than 10.0 without gapping: 37282 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 38932 length of database: 575,637,011 effective HSP length: 100 effective length of database: 409,908,611 effective search space used: 73373641369 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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