Bombyx BLAST Result against human

BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= prgv0895
         (696 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC060857-1|AAH60857.1|  525|Homo sapiens cytochrome P450, family...    95   2e-19
AY422002-1|AAR31180.1|  525|Homo sapiens cytochrome P450 4V2 pro...    95   2e-19
AK126473-1|BAC86562.1|  503|Homo sapiens protein ( Homo sapiens ...    95   2e-19
AK122600-1|BAC85487.1|  525|Homo sapiens protein ( Homo sapiens ...    95   2e-19
D26480-1|BAA05490.1|  520|Homo sapiens leukotriene B4 omega-hydr...    86   1e-16
BC067439-1|AAH67439.1|  520|Homo sapiens cytochrome P450, family...    86   1e-16
BC067437-1|AAH67437.1|  520|Homo sapiens cytochrome P450, family...    86   1e-16
AF467894-1|AAL67578.1|  520|Homo sapiens cytochrome P450, subfam...    86   1e-16
AC005336-1|AAC27730.1|  520|Homo sapiens CYP4F2 protein.               86   1e-16
U02388-1|AAC50052.2|  520|Homo sapiens cytochrome P450 4F2 protein.    85   3e-16
BC067440-1|AAH67440.1|  520|Homo sapiens cytochrome P450, family...    85   3e-16
AB015306-1|BAA75823.1|  520|Homo sapiens Leukotriene B4 omega-hy...    85   3e-16
L04751-1|AAA58436.1|  519|Homo sapiens cytochrome P450 protein.        82   2e-15
D26481-1|BAA05491.1|  519|Homo sapiens fatty acids omega-hydroxy...    82   2e-15
AY369778-1|AAQ56847.1|  519|Homo sapiens cytochrome P450, family...    82   2e-15
AY280371-1|AAQ21367.1|  519|Homo sapiens cytochrome P450 4A22K p...    82   2e-15
AL731892-3|CAH72778.1|  519|Homo sapiens cytochrome P450, family...    82   2e-15
D13705-1|BAA02864.1|  521|Homo sapiens fatty acid omega-hydroxyl...    81   3e-15
AY792513-1|AAV40834.1|  520|Homo sapiens cytochrome P450, family...    81   4e-15
AF054821-1|AAC08589.1|  520|Homo sapiens cytochrome P-450 protein.     81   4e-15
D12620-1|BAA02144.1|  520|Homo sapiens cytochrome P-450LTBV prot...    81   5e-15
AL135960-9|CAI19737.1|  519|Homo sapiens cytochrome P450, family...    81   5e-15
AF208532-1|AAF76722.1|  519|Homo sapiens fatty acid omega-hydrox...    81   5e-15
AB002461-1|BAA25991.1|  520|Homo sapiens leukotriene B4 omega-hy...    81   5e-15
AB002454-1|BAA25990.1|  520|Homo sapiens leukotriene B4 omega-hy...    81   5e-15
AF525488-1|AAO16078.1|  519|Homo sapiens cytochrome P450, subfam...    80   6e-15
X16699-1|CAA34672.1|  511|Homo sapiens protein ( Human mRNA for ...    80   9e-15
J02871-1|AAA35712.1|  511|Homo sapiens protein ( Human lung cyto...    80   9e-15
DQ518907-1|ABF47106.1|  511|Homo sapiens cytochrome P450, family...    80   9e-15
BC017758-1|AAH17758.1|  512|Homo sapiens cytochrome P450, family...    80   9e-15
AY151049-1|AAN72312.1|  497|Homo sapiens pulmonary cytochrome P4...    80   9e-15
AY151048-1|AAN72311.1|  512|Homo sapiens pulmonary cytochrome P4...    80   9e-15
AY064486-1|AAL57721.1|  511|Homo sapiens cytochrome P450 protein.      80   9e-15
AY064485-1|AAL57720.1|  511|Homo sapiens cytochrome P450 protein.      80   9e-15
AL593856-7|CAI16982.1|  512|Homo sapiens cytochrome P450, family...    80   9e-15
AL593856-6|CAI16981.1|  511|Homo sapiens cytochrome P450, family...    80   9e-15
AL593856-5|CAI16983.1|  497|Homo sapiens cytochrome P450, family...    80   9e-15
AL356793-4|CAI22557.1|  512|Homo sapiens cytochrome P450, family...    80   9e-15
AL356793-3|CAI22559.1|  511|Homo sapiens cytochrome P450, family...    80   9e-15
AL356793-2|CAI22558.1|  497|Homo sapiens cytochrome P450, family...    80   9e-15
AF491285-1|AAM09532.1|  511|Homo sapiens cytochrome P450 protein.      80   9e-15
AF133298-1|AAD49566.1|  520|Homo sapiens cytochrome P450 protein.      79   1e-14
S67581-1|AAB29503.1|  591|Homo sapiens fatty acid omega-hydroxyl...    79   2e-14
S67580-1|AAB29502.1|  519|Homo sapiens fatty acid omega-hydroxyl...    79   2e-14
BC035350-1|AAH35350.1|  524|Homo sapiens cytochrome P450, family...    79   2e-14
AY358977-1|AAQ89336.1|  524|Homo sapiens CYP4F12 protein.              79   2e-14
AY008841-1|AAG33247.1|  524|Homo sapiens cytochrome P450 isoform...    79   2e-14
AC004523-1|AAC11543.1|  458|Homo sapiens F22329_1 protein.             79   2e-14
AB035131-1|BAB18270.1|  524|Homo sapiens cytochrome P450 protein.      79   2e-14
AB035130-1|BAB18269.1|  524|Homo sapiens cytochrome P450 protein.      79   2e-14
AY280372-1|AAQ21368.1|  519|Homo sapiens cytochrome P450 4A22 pr...    78   3e-14
BC093896-1|AAH93896.1|  531|Homo sapiens cytochrome P450, family...    75   2e-13
BC093894-1|AAH93894.1|  531|Homo sapiens cytochrome P450, family...    75   2e-13
BC069351-1|AAH69351.1|  531|Homo sapiens cytochrome P450, family...    75   2e-13
AK096820-1|BAC04868.1|  531|Homo sapiens protein ( Homo sapiens ...    75   2e-13
BC028102-1|AAH28102.1|  509|Homo sapiens cytochrome P450, family...    74   4e-13
AY358537-1|AAQ88901.1|  509|Homo sapiens EFSW1929 protein.             74   4e-13
AM040940-1|CAJ13826.1|  509|Homo sapiens cytochrome P450 protein.      74   4e-13
AL450996-1|CAH71035.1|  509|Homo sapiens cytochrome P450, family...    74   4e-13
AK131355-1|BAD18508.1|  508|Homo sapiens protein ( Homo sapiens ...    74   4e-13
AK098065-1|BAC05226.1|  509|Homo sapiens protein ( Homo sapiens ...    74   4e-13
AK091806-1|BAC03751.1|  444|Homo sapiens protein ( Homo sapiens ...    74   4e-13
AF280109-1|AAG33010.1|  504|Homo sapiens cytochrome P450 subfami...    74   4e-13
AC011904-5|AAS07394.1|  504|Homo sapiens unknown protein.              74   4e-13
AF236085-1|AAG15889.1|  524|Homo sapiens CYP4F11 protein.              74   6e-13
BC016853-1|AAH16853.1|  524|Homo sapiens CYP4F11 protein protein.      73   7e-13
AY390424-1|AAQ92352.1|  503|Homo sapiens cytochrome P450 CYP3A43...    73   7e-13
AL135960-10|CAI19736.1|  421|Homo sapiens cytochrome P450, famil...    73   7e-13
M18907-1|AAA35745.1|  503|Homo sapiens protein ( Human P450 mRNA...    73   1e-12
DQ924960-1|ABI96208.1|  503|Homo sapiens cytochrome P450 family ...    73   1e-12
DQ005611-1|AAY16980.1|  503|Homo sapiens cytochrome P450, family...    73   1e-12
BC101631-1|AAI01632.1|  503|Homo sapiens cytochrome P450, subfam...    73   1e-12
BC069418-1|AAH69418.1|  503|Homo sapiens cytochrome P450, family...    73   1e-12
AJ563377-1|CAD91345.1|  353|Homo sapiens cytochrome P450 protein.      73   1e-12
AJ563376-2|CAD91645.1|  430|Homo sapiens cytochrome P450 protein.      73   1e-12
AJ563375-1|CAD91343.1|  503|Homo sapiens cytochrome P450 protein.      73   1e-12
AF280107-2|AAG32290.1|  503|Homo sapiens cytochrome P450 polypep...    73   1e-12
AF209389-1|AAF21034.1|  503|Homo sapiens cytochrome P450 IIIA4 p...    73   1e-12
AF182273-1|AAF13598.1|  503|Homo sapiens cytochrome P450-3A4 pro...    73   1e-12
BC100981-1|AAI00982.1|  393|Homo sapiens CYP3A43 protein protein.      73   1e-12
AY390425-1|AAQ92353.1|  503|Homo sapiens cytochrome P450 CYP3A43...    73   1e-12
AF337813-1|AAK38841.1|  503|Homo sapiens cytochrome P450 subfami...    73   1e-12
AF319634-1|AAK00325.1|  503|Homo sapiens cytochrome P450 CYP3A43...    73   1e-12
AF280108-1|AAG33009.1|  503|Homo sapiens cytochrome P450 subfami...    73   1e-12
AC011904-4|AAS07395.1|  503|Homo sapiens unknown protein.              73   1e-12
X12387-1|CAA30944.1|  503|Homo sapiens protein ( Human mRNA for ...    72   2e-12
M14096-1|AAA35744.1|  503|Homo sapiens protein ( Human cytochrom...    72   2e-12
M13785-1|AAA35742.1|  504|Homo sapiens protein ( Human liver glu...    72   2e-12
J04449-1|AAA35747.1|  502|Homo sapiens cytochrome P450 nifedipin...    72   2e-12
D00003-1|BAA00001.1|  504|Homo sapiens cytochrome P-450 protein.       72   2e-12
J04813-1|AAA02993.1|  502|Homo sapiens cytochrome P450 PCN3 prot...    69   2e-11
BC033862-1|AAH33862.1|  502|Homo sapiens cytochrome P450, family...    69   2e-11
AC005020-1|AAS02016.1|  502|Homo sapiens unknown protein.              69   2e-11
X71480-1|CAA50586.1|  141|Homo sapiens cytochrome P450 protein.        69   2e-11
D00408-1|BAA00310.1|  503|Homo sapiens cytochrome P-450 HFLa pro...    69   2e-11
BC067436-1|AAH67436.1|  503|Homo sapiens cytochrome P450, family...    69   2e-11
AF315325-1|AAG48618.1|  535|Homo sapiens cytochrome P450 variant...    69   2e-11
AF280107-3|AAG32289.1|  503|Homo sapiens cytochrome P450 polypep...    69   2e-11
AK223008-1|BAD96728.1|  502|Homo sapiens cytochrome P450, family...    68   3e-11
AY358631-1|AAQ88994.1|  505|Homo sapiens EPSW3060 protein.             67   5e-11
AY262056-1|AAO89257.1|  505|Homo sapiens cytochrome P450 protein.      67   5e-11
AL450996-2|CAH71036.1|  505|Homo sapiens cytochrome P450, family...    67   5e-11
AL135960-6|CAI19734.1|  505|Homo sapiens cytochrome P450, family...    67   5e-11
BC041158-1|AAH41158.1|  455|Homo sapiens CYP4A11 protein protein.      66   9e-11
AL731892-4|CAH72779.1|  455|Homo sapiens cytochrome P450, family...    66   9e-11
BC142607-1|AAI42608.1|  455|Homo sapiens CYP4A22 protein protein.      66   1e-10
AL135960-11|CAI19738.1|  455|Homo sapiens cytochrome P450, famil...    66   1e-10
BC022539-1|AAH22539.1|  500|Homo sapiens cytochrome P450, family...    64   3e-10
AF094480-1|AAD41244.1|  500|Homo sapiens cholesterol 24-hydroxyl...    64   3e-10
AJ563378-3|CAD91347.1|  173|Homo sapiens hypothetical protein pr...    63   8e-10
AJ563378-2|CAD91647.1|  160|Homo sapiens cytochrome P450 protein.      63   8e-10
AF233624-1|AAF99278.1|  534|Homo sapiens thromboxane synthase pr...    62   1e-09
M80647-1|AAA60618.1|  534|Homo sapiens thromboxane synthase prot...    60   7e-09
BC041157-1|AAH41157.1|  534|Homo sapiens thromboxane A synthase ...    60   7e-09
BC014117-1|AAH14117.1|  466|Homo sapiens TBXAS1 protein protein.       60   7e-09
AK223466-1|BAD97186.1|  534|Homo sapiens thromboxane A synthase ...    60   7e-09
AF233625-1|AAF99279.1|  534|Homo sapiens thromboxane synthase pr...    60   7e-09
AF233623-1|AAF99277.1|  534|Homo sapiens thromboxane synthase pr...    60   7e-09
AF233621-1|AAF99275.1|  534|Homo sapiens thromboxane synthase pr...    60   7e-09
AF233620-1|AAF99274.1|  534|Homo sapiens thromboxane synthase pr...    60   7e-09
AF233619-1|AAF99273.1|  534|Homo sapiens thromboxane synthase pr...    60   7e-09
AF233618-1|AAF99272.1|  534|Homo sapiens thromboxane synthase pr...    60   7e-09
AF233617-1|AAF99271.1|  534|Homo sapiens thromboxane synthase pr...    60   7e-09
AF233616-1|AAF99270.1|  534|Homo sapiens thromboxane synthase pr...    60   7e-09
AF233615-1|AAF99269.1|  534|Homo sapiens thromboxane synthase pr...    60   7e-09
L13286-1|AAA62379.1|  513|Homo sapiens 1,25-dihydroxyvitamin D3 ...    59   2e-08
D34625-1|BAA07011.1|  533|Homo sapiens thromboxane synthase prot...    59   2e-08
AF233622-1|AAF99276.1|  534|Homo sapiens thromboxane synthase pr...    59   2e-08
BC142690-1|AAI42691.1|  357|Homo sapiens CYP4A22 protein protein.      58   2e-08
Y07508-1|CAA68807.1|  503|Homo sapiens protein ( Human mRNA for ...    58   4e-08
X13589-1|CAA31929.1|  503|Homo sapiens protein ( Human mRNA for ...    58   4e-08
M30804-1|AAA35728.1|  503|Homo sapiens protein ( Human aromatase...    58   4e-08
M28420-1|AAA52141.1|  419|Homo sapiens cytochrome P-450 aromatas...    58   4e-08
M22246-1|AAA35557.1|  503|Homo sapiens protein ( Human aromatase...    58   4e-08
M18856-1|AAA35556.1|  419|Homo sapiens protein ( Human aromatase...    58   4e-08
J04127-1|AAA52132.1|  503|Homo sapiens CYP19 protein.                  58   4e-08
DQ118405-1|AAZ23558.1|  503|Homo sapiens cytochrome P450 subfami...    58   4e-08
BC107785-1|AAI07786.1|  503|Homo sapiens cytochrome P450, family...    58   4e-08
BC035959-1|AAH35959.1|  503|Homo sapiens cytochrome P450, family...    58   4e-08
AY957953-1|AAX44046.1|  503|Homo sapiens cytochrome P450, family...    58   4e-08
BC100982-1|AAI00983.1|  280|Homo sapiens CYP3A43 protein protein.      57   5e-08
AF280110-1|AAG33011.1|  420|Homo sapiens cytochrome P450 subfami...    57   5e-08
S67623-1|AAB29308.1|  257|Homo sapiens 25-hydroxyvitamin D 24-hy...    56   9e-08
D12621-1|BAA02145.1|  389|Homo sapiens cytochrome P-450LTBV prot...    56   9e-08
AY858838-1|AAW50795.1|  372|Homo sapiens vitamin D 24-hydroxylas...    56   9e-08
AL138805-2|CAB91829.1|  514|Homo sapiens cytochrome P450, family...    56   9e-08
AL138805-1|CAM27342.1|  372|Homo sapiens cytochrome P450, family...    56   9e-08
X59812-1|CAA42481.1|  530|Homo sapiens Vitamin D3 25-hydroxylase...    55   2e-07
M63871-1|AAA59984.1|  508|Homo sapiens CYP17 protein.                  55   2e-07
M62401-1|AAA52142.1|  531|Homo sapiens sterol 27-hydroxylase pro...    55   2e-07
M31153-1|AAA52140.1|  508|Homo sapiens CYP17 protein.                  55   2e-07
M19489-1|AAA36405.1|  508|Homo sapiens CYP17 protein.                  55   2e-07
M14564-1|AAA52151.1|  508|Homo sapiens CYP17 protein.                  55   2e-07
DQ530598-1|ABF50972.1|  508|Homo sapiens cytochrome P450, family...    55   2e-07
BT020000-1|AAV38803.1|  508|Homo sapiens cytochrome P450, family...    55   2e-07
BC063388-1|AAH63388.1|  508|Homo sapiens cytochrome P450, family...    55   2e-07
BC062997-1|AAH62997.1|  508|Homo sapiens cytochrome P450, family...    55   2e-07
BC051851-1|AAH51851.1|  531|Homo sapiens cytochrome P450, family...    55   2e-07
BC040430-1|AAH40430.1|  531|Homo sapiens cytochrome P450, family...    55   2e-07
AY178622-1|AAO21126.1|  531|Homo sapiens steroid hydroxylase pro...    55   2e-07
AL358790-3|CAI52498.1|  508|Homo sapiens cytochrome P450, family...    55   2e-07
BC032322-1|AAH32322.1|  509|Homo sapiens cytochrome P450, family...    54   4e-07
U51692-1|AAC50951.1|  503|Homo sapiens lanosterol 14-alpha demet...    54   5e-07
U23942-1|AAB39951.1|  509|Homo sapiens lanosterol 14-demethylase...    54   5e-07
D55653-1|BAA09512.1|  509|Homo sapiens lanosterol 14-demethylase...    54   5e-07
AC000120-2|AAB46356.1|  509|Homo sapiens unknown protein.              54   5e-07
BC132767-1|AAI32768.1|  544|Homo sapiens cytochrome P450, family...    54   6e-07
AY343323-1|AAQ21380.1|  544|Homo sapiens cytochrome P450 protein.      54   6e-07
M32881-1|AAA35741.1|  503|Homo sapiens protein ( Human steroid 1...    51   5e-06
BC067429-1|AAH67429.1|  516|Homo sapiens cytochrome P450, family...    50   1e-05
X54741-1|CAA38539.1|  503|Homo sapiens aldosterone  synthase (P-...    49   2e-05
D13752-1|BAA02899.1|  503|Homo sapiens steroid 18-hydroxylase pr...    49   2e-05
M80646-1|AAA60617.1|  460|Homo sapiens thromboxane synthase prot...    47   6e-05
AL358613-3|CAH72804.1|  428|Homo sapiens cytochrome P450, family...    47   6e-05
AL358613-2|CAH72803.1|  497|Homo sapiens cytochrome P450, family...    47   6e-05
AF005418-1|AAB88881.1|  497|Homo sapiens retinoic acid hydroxyla...    47   6e-05
M24667-1|AAA52148.1|  256|Homo sapiens steroid 11-beta-hydroxyla...    47   7e-05
X55764-1|CAA39290.1|  503|Homo sapiens protein ( Human mRNA for ...    46   1e-04
U37143-1|AAC50370.2|  502|Homo sapiens cytochrome P450 monooxyge...    46   2e-04
BC039307-1|AAH39307.1|  372|Homo sapiens cytochrome P450, family...    46   2e-04
BC032594-1|AAH32594.1|  502|Homo sapiens cytochrome P450, family...    46   2e-04
AY426985-1|AAQ93356.1|  502|Homo sapiens cytochrome P450, family...    46   2e-04
AK131190-1|BAD18388.1|  372|Homo sapiens .-.-).  protein.              46   2e-04
AK090886-1|BAC03539.1|  337|Homo sapiens protein ( Homo sapiens ...    46   2e-04
AF272142-1|AAM44456.1|  502|Homo sapiens cytochrome P450 protein.      46   2e-04
AB080265-1|BAB85489.1|  502|Homo sapiens cytochrome P450 2J2 pro...    45   2e-04
X05367-1|CAA28965.1|  521|Homo sapiens desmolase protein.              45   3e-04
M32879-1|AAA52149.1|  503|Homo sapiens CYP11B1 protein.                45   3e-04
M28253-1|AAA36404.1|  239|Homo sapiens cytochrome P-450-scc prot...    45   3e-04
M14565-1|AAA52162.1|  521|Homo sapiens CYP11A protein.                 45   3e-04
BC096287-1|AAH96287.1|  503|Homo sapiens cytochrome P450, family...    45   3e-04
BC096285-1|AAH96285.1|  574|Homo sapiens CYP11B1 protein protein.      45   3e-04
BC032329-1|AAH32329.1|  521|Homo sapiens cytochrome P450, family...    45   3e-04
AF478474-1|AAL84813.1|  503|Homo sapiens mutated cytochrome P-45...    45   3e-04
AY288916-1|AAP31972.1|  508|Homo sapiens cytochrome P450, family...    44   5e-04
AF256213-1|AAG00416.1|  508|Homo sapiens 25- hydroxyvitamin D-1-...    44   5e-04
AF246895-1|AAF64299.1|  508|Homo sapiens 25-hydroxyvitamin D-1-a...    44   5e-04
AF027152-1|AAC51854.1|  508|Homo sapiens P450 25-hydroxyvitamin ...    44   5e-04
AF020192-1|AAC51853.1|  508|Homo sapiens 25-hydroxyvitamin D-1-a...    44   5e-04
AB006987-1|BAA23418.1|  508|Homo sapiens 25-hydroxyvitamin D3 1-...    44   5e-04
AB005990-1|BAA22657.1|  508|Homo sapiens 25-hydroxyvitamin D3 1a...    44   5e-04
AB005989-1|BAA22656.1|  508|Homo sapiens 25-hydroxyvitamin D3 1a...    44   5e-04
AB005038-1|BAA23416.1|  508|Homo sapiens 25-hydroxyvitamin D3 1-...    44   5e-04
X02612-1|CAA26458.1|  512|Homo sapiens cytochrome P(1)-450 protein.    43   0.001
X04300-1|CAA27843.1|  512|Homo sapiens P-450 c protein.                43   0.001
M12079-1|AAA52152.1|  191|Homo sapiens POR protein.                    43   0.001
K03191-1|AAA52139.1|  512|Homo sapiens CYP1A1 protein.                 43   0.001
EF094025-1|ABK41999.1|  512|Homo sapiens cytochrome P450, family...    43   0.001
BC023019-1|AAH23019.1|  512|Homo sapiens cytochrome P450, family...    43   0.001
AY310359-1|AAQ76692.1|  484|Homo sapiens cytochrome P450 1A1 var...    43   0.001
AM236047-1|CAJ84704.1|  251|Homo sapiens cytochrome P450 1A1 pro...    43   0.001
AK223113-1|BAD96833.1|  512|Homo sapiens cytochrome P450, family...    43   0.001
AK223108-1|BAD96828.1|  512|Homo sapiens cytochrome P450, family...    43   0.001
AF253322-1|AAK25727.1|  512|Homo sapiens cytochrome P450 protein.      43   0.001
M28548-1|AAA52065.1|  495|Homo sapiens protein ( Human mutant 21...    42   0.003
M26856-1|AAA52064.1|  495|Homo sapiens protein ( Human 21-hydrox...    42   0.003
M21550-1|AAA52063.1|  495|Homo sapiens CYP21 protein.                  42   0.003
M13936-1|AAA59695.1|  494|Homo sapiens CYP21P protein.                 42   0.003
BX679671-8|CAM26070.1|  494|Homo sapiens cytochrome P450, family...    42   0.003
BX679671-7|CAM26071.1|  464|Homo sapiens cytochrome P450, family...    42   0.003
BC125182-1|AAI25183.1|  494|Homo sapiens cytochrome P450, family...    42   0.003
BC125181-1|AAI25182.1|  495|Homo sapiens cytochrome P450, family...    42   0.003
BC010358-1|AAH10358.1|  469|Homo sapiens cytochrome P450, family...    42   0.003
AM183951-1|CAJ75805.1|  494|Homo sapiens steroid 21-hydroxylase,...    42   0.003
AM183949-1|CAJ75803.1|  494|Homo sapiens steroid 21-hydroxylase,...    42   0.003
AM183948-1|CAJ75802.1|  494|Homo sapiens steroid 21-hydroxylase ...    42   0.003
AM183947-1|CAJ75801.1|  494|Homo sapiens steroid 21-hydroxylase,...    42   0.003
AM183946-1|CAJ75800.1|  494|Homo sapiens steroid 21-hydroxylase,...    42   0.003
AM183945-1|CAJ75799.1|  494|Homo sapiens steroid 21-hydroxylase,...    42   0.003
AM086565-1|CAJ31104.1|  494|Homo sapiens steroid 21-hydroxylase,...    42   0.003
AM086564-1|CAJ31103.1|  494|Homo sapiens steroid 21-hydroxylase,...    42   0.003
AL929593-2|CAI41778.1|  465|Homo sapiens cytochrome P450, family...    42   0.003
AL929593-1|CAI41779.1|  495|Homo sapiens cytochrome P450, family...    42   0.003
AL662849-19|CAI17480.1|  465|Homo sapiens cytochrome P450, famil...    42   0.003
AL662849-18|CAI17479.1|  495|Homo sapiens cytochrome P450, famil...    42   0.003
AL645922-24|CAI41754.1|  495|Homo sapiens cytochrome P450, famil...    42   0.003
AL645922-23|CAI41755.1|  465|Homo sapiens cytochrome P450, famil...    42   0.003
AL591242-1|CAH73899.1|  469|Homo sapiens cytochrome P450, family...    42   0.003
AL049547-7|CAB89301.1|  495|Homo sapiens dJ34F7.3 (cytochrome P4...    42   0.003
AL035670-1|CAI20276.1|  469|Homo sapiens cytochrome P450, family...    42   0.003
AK054616-1|BAB70774.1|  465|Homo sapiens protein ( Homo sapiens ...    42   0.003
AF237982-1|AAF63329.1|  469|Homo sapiens oxysterol 7alpha-hydrox...    42   0.003
AF077974-1|AAD45405.1|  403|Homo sapiens cytochrome P450 21-hydr...    42   0.003
AF019413-2|AAB67982.1|  495|Homo sapiens cytochrome P450 21-hydr...    42   0.003
X58906-1|CAA41709.1|  495|Homo sapiens steroid 21-monooxygenase ...    41   0.004
L36085-1|AAC01761.1|  441|Homo sapiens thromboxane A2 synthase p...    41   0.004
BC109084-1|AAI09085.1|  448|Homo sapiens CYP24A1 protein protein.      41   0.005
BC109083-1|AAI09084.1|  448|Homo sapiens CYP24A1 protein protein.      41   0.005
AM183950-1|CAJ75804.1|  494|Homo sapiens steroid 21-hydroxylase,...    41   0.005
AL138805-3|CAM27343.1|  448|Homo sapiens cytochrome P450, family...    41   0.005
M17252-1|AAA59985.1|  230|Homo sapiens CYP21 protein.                  40   0.006
AM233518-1|CAJ80721.1|  157|Homo sapiens cytochrome P450 1A1 pro...    39   0.020
AM233517-1|CAJ80720.1|  175|Homo sapiens cytochrome P450 1A1 pro...    39   0.020
AF040259-1|AAD10199.1|  144|Homo sapiens cytochrome P450 1A1 pro...    39   0.020
M12792-1|AAB59440.1|  494|Homo sapiens steroid 21-hydroxylase pr...    38   0.034
BC093022-1|AAH93022.1|  416|Homo sapiens CYP20A1 protein protein.      38   0.034
BC033752-1|AAH33752.1|  462|Homo sapiens cytochrome P450, family...    38   0.034
BC020616-1|AAH20616.1|  462|Homo sapiens cytochrome P450, family...    38   0.034
AY359068-1|AAQ89427.1|  462|Homo sapiens P450-like protein protein.    38   0.034
AC011737-1|AAX88915.1|  382|Homo sapiens unknown protein.              38   0.034
X13930-1|CAA32118.1|  494|Homo sapiens protein ( Human CYP2A4 mR...    38   0.045
X13929-1|CAA32117.1|  448|Homo sapiens P-450 IIA3 protein (1 is ...    38   0.045
M33318-1|AAA52067.1|  494|Homo sapiens CYP2A protein.                  38   0.045
BC096256-1|AAH96256.1|  494|Homo sapiens cytochrome P450, family...    38   0.045
BC096255-1|AAH96255.1|  494|Homo sapiens cytochrome P450, family...    38   0.045
BC096254-1|AAH96254.1|  494|Homo sapiens cytochrome P450, family...    38   0.045
BC096253-1|AAH96253.3|  494|Homo sapiens cytochrome P450, family...    38   0.045
AF182275-1|AAF13600.1|  494|Homo sapiens cytochrome P450-2A6 pro...    38   0.045
U22029-1|AAB40520.1|  494|Homo sapiens cytochrome P450 protein.        36   0.10 
U22027-1|AAB40518.1|  494|Homo sapiens cytochrome P450 protein.        36   0.10 
M33317-1|AAA52138.1|  494|Homo sapiens CYP2A protein.                  36   0.10 
BC117165-1|AAI17166.1|  494|Homo sapiens cytochrome P450, family...    36   0.10 
X13897-1|CAA32097.1|  489|Homo sapiens protein ( Human mRNA for ...    36   0.14 
BC109205-1|AAI09206.1|  512|Homo sapiens cytochrome P450, family...    36   0.18 
BC069443-1|AAH69443.1|  512|Homo sapiens cytochrome P450, family...    36   0.18 
AF252297-1|AAF76003.1|  512|Homo sapiens cytochrome P450 retinoi...    36   0.18 
AC007002-1|AAY14690.1|  512|Homo sapiens unknown protein.              36   0.18 
AF183412-1|AAG09681.1|  435|Homo sapiens cytochrome P450 monooxy...    35   0.24 
Y00498-1|CAA68550.1|  490|Homo sapiens IIC2 protein.                   35   0.32 
X51535-1|CAA35915.1|  210|Homo sapiens cytochrome P-450 HPH (120...    35   0.32 
M21942-1|AAA52161.1|  462|Homo sapiens CYP2C protein.                  35   0.32 
M17397-1|AAA35739.1|  490|Homo sapiens protein ( Human cytochrom...    35   0.32 
K03192-1|AAA52147.1|  331|Homo sapiens CYP1A1 protein.                 35   0.32 
BC020596-1|AAH20596.1|  490|Homo sapiens cytochrome P450, family...    35   0.32 
AY514490-1|AAR89907.1|  490|Homo sapiens cytochrome P450, family...    35   0.32 
AL359672-5|CAH71307.1|  490|Homo sapiens cytochrome P450, family...    35   0.32 
S46963-1|AAB23864.2|  477|Homo sapiens cytochrome P-450 protein.       34   0.42 
M21940-1|AAA52159.1|  383|Homo sapiens CYP2C protein.                  34   0.42 
M21939-1|AAA52158.1|  485|Homo sapiens CYP2C protein.                  34   0.42 
M15331-1|AAA52157.1|  485|Homo sapiens CYP2C protein.                  34   0.42 
L16883-1|AAD13467.1|  169|Homo sapiens cytochrome P-450 2C protein.    34   0.42 
D00173-1|BAA00123.1|  487|Homo sapiens cytochrome P-450 protein.       34   0.42 
BC125054-1|AAI25055.1|  490|Homo sapiens cytochrome P450, family...    34   0.42 
AY871801-1|AAX62803.1|  483|Homo sapiens cytochrome P450 family ...    34   0.42 
AY702706-1|AAT94065.1|  490|Homo sapiens cytochrome P450, family...    34   0.42 
AY341248-1|AAP88931.1|  490|Homo sapiens cytochrome P450, family...    34   0.42 
AL359672-1|CAH71303.1|  490|Homo sapiens cytochrome P450, family...    34   0.42 
X65962-1|CAA46778.1|  356|Homo sapiens cytochrome P-450 II C pro...    34   0.56 
M61858-1|AAA52145.1|  370|Homo sapiens CYP2C17 protein.                34   0.56 
M61854-1|AAB59426.1|  490|Homo sapiens cytochrome protein.             34   0.56 
L39102-1|AAL31348.1|  217|Homo sapiens S-mephenytoin 4-hydroxyla...    34   0.56 
L07093-1|AAA36660.1|  468|Homo sapiens cytochrome P450 protein.        34   0.56 
AY796203-1|AAV41877.1|  490|Homo sapiens cytochrome P450, family...    34   0.56 
AL583836-2|CAH74068.1|  490|Homo sapiens cytochrome P450, family...    34   0.56 
AL133513-2|CAH73444.1|  490|Homo sapiens cytochrome P450, family...    34   0.56 
M21941-1|AAA52160.1|  480|Homo sapiens CYP2C protein.                  33   0.97 
BC096259-1|AAH96259.1|  443|Homo sapiens CYP2C18 protein protein.      33   0.97 
M61856-1|AAB59356.1|  490|Homo sapiens cytochrome protein.             33   1.3  
L16876-1|AAA02630.1|  490|Homo sapiens cytochrome P-4502C18 prot...    33   1.3  
BX538127-1|CAD98029.1|  310|Homo sapiens hypothetical protein pr...    33   1.3  
BC096260-1|AAH96260.1|  431|Homo sapiens CYP2C18 protein protein.      33   1.3  
BC096258-1|AAH96258.1|  490|Homo sapiens cytochrome P450, family...    33   1.3  
BC096257-1|AAH96257.1|  490|Homo sapiens cytochrome P450, family...    33   1.3  
BC069666-1|AAH69666.1|  490|Homo sapiens cytochrome P450, family...    33   1.3  
AL583836-1|CAH74067.1|  490|Homo sapiens cytochrome P450, family...    33   1.3  
AK223510-1|BAD97230.1|  490|Homo sapiens cytochrome P450, family...    33   1.3  
M29874-1|AAA52144.1|  491|Homo sapiens CYP2B protein.                  32   1.7  
DQ298753-1|ABB84469.1|  491|Homo sapiens cytochrome P450, family...    32   1.7  
BC067431-1|AAH67431.1|  491|Homo sapiens cytochrome P450, family...    32   1.7  
BC067430-1|AAH67430.1|  491|Homo sapiens cytochrome P450, family...    32   1.7  
AF182277-1|AAF13602.1|  491|Homo sapiens cytochrome P450-2B6 pro...    32   1.7  
AC023172-1|AAF32444.1|  491|Homo sapiens CYP2B6 protein.               32   1.7  
J02843-1|AAA52155.1|  493|Homo sapiens protein ( Human cytochrom...    32   2.2  
J02625-1|AAA35743.1|  493|Homo sapiens protein ( Human cytochrom...    32   2.2  
DQ515958-1|ABF47105.1|  493|Homo sapiens cytochrome P450, family...    32   2.2  
DQ149222-1|AAZ77710.1|  493|Homo sapiens cytochrome P450 2E1 pro...    32   2.2  
BC067435-1|AAH67435.1|  493|Homo sapiens cytochrome P450, family...    32   2.2  
BC067433-1|AAH67433.1|  493|Homo sapiens cytochrome P450, family...    32   2.2  
BC033691-1|AAH33691.1|  504|Homo sapiens cytochrome P450, family...    32   2.2  
AY358603-1|AAQ88966.1|  504|Homo sapiens Cytochrome p450 protein.      32   2.2  
AL161645-2|CAH70047.1|  493|Homo sapiens cytochrome P450, family...    32   2.2  
AK027605-1|BAB55227.1|  564|Homo sapiens protein ( Homo sapiens ...    32   2.2  
AJ877238-1|CAI47002.1|   97|Homo sapiens putative cytochrome P45...    32   2.2  
AF335278-1|AAK13498.1|  504|Homo sapiens cytochrome P450 2S1 pro...    32   2.2  
AF182276-1|AAF13601.1|  493|Homo sapiens cytochrome P450-2E1 pro...    32   2.2  
AF084225-1|AAD13753.1|  462|Homo sapiens cytochrome P450 2E1 pro...    32   2.2  
AB209700-1|BAD92937.1|  336|Homo sapiens cytochrome P450, family...    32   2.2  
BC041391-1|AAH41391.1|  731|Homo sapiens TACC1 protein protein.        31   3.0  
AY513609-1|AAR90940.1|  494|Homo sapiens cytochrome P450 2A13 va...    31   3.0  
AY513608-1|AAR90939.1|  494|Homo sapiens cytochrome P450 2A13 va...    31   3.0  
AY513606-1|AAR90937.1|  494|Homo sapiens cytochrome P450 2A13 va...    31   3.0  
AY513605-1|AAR90936.1|  494|Homo sapiens cytochrome P450 2A13 va...    31   3.0  
AY513604-1|AAR90935.1|  494|Homo sapiens cytochrome P450 2A13 va...    31   3.0  
AY072876-1|AAL62463.2|  348|Homo sapiens transforming, acidic co...    31   3.0  
AF209774-1|AAG35775.1|  494|Homo sapiens cytochrome P450 2A13 pr...    31   3.0  
AF049910-1|AAC32327.1|  805|Homo sapiens TACC1 protein.                31   3.0  
AB029026-1|BAA83055.1|  453|Homo sapiens KIAA1103 protein protein.     31   3.0  
X58904-1|CAA41707.1|  371|Homo sapiens steroid 21-monooxygenase ...    31   3.9  
X58902-1|CAA41706.1|  372|Homo sapiens steroid 21-monooxygenase ...    31   3.9  
X58900-1|CAA41704.1|  372|Homo sapiens steroid 21-monooxygenase ...    31   3.9  
X58899-1|CAA41703.1|  368|Homo sapiens steroid 21-monooxygenase ...    31   3.9  
X58898-1|CAA41702.1|  371|Homo sapiens steroid 21-monooxygenase ...    31   3.9  
J02906-1|AAA52156.1|  491|Homo sapiens CYP2F1 protein.                 31   3.9  
EF122241-1|ABO41976.1|  491|Homo sapiens cytochrome P450 2F1 var...    31   3.9  
AF372573-1|AAL69652.1|  495|Homo sapiens cytochrome P450 2F1 pro...    31   3.9  
AJ563379-2|CAD91649.1|   84|Homo sapiens cytochrome P450 protein.      31   5.2  
AK127151-1|BAC86855.1|  146|Homo sapiens protein ( Homo sapiens ...    30   6.9  
AY154464-1|AAO18160.1|  986|Homo sapiens NALP9 protein.                30   9.1  

>BC060857-1|AAH60857.1|  525|Homo sapiens cytochrome P450, family 4,
           subfamily V, polypeptide 2 protein.
          Length = 525

 Score = 95.5 bits (227), Expect = 2e-19
 Identities = 51/138 (36%), Positives = 75/138 (54%)
 Frame = +3

Query: 240 GYSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQE 419
           G +  +Q KV  ELD +FG SDRP T +D  +++YLE  + ETLRL+P VP+ AR V+++
Sbjct: 346 GSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSED 405

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLG 599
             +   G ++  GT  VI  Y LHR P  +           F              F  G
Sbjct: 406 CEVA--GYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 463

Query: 600 PRSCVGRKYAMLKLKVIL 653
           PR+C+G+K+A+++ K IL
Sbjct: 464 PRNCIGQKFAVMEEKTIL 481



 Score = 56.8 bits (131), Expect = 7e-08
 Identities = 29/62 (46%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + KR AFLDLLL  +   G  +S E+I+E+VDT MFEGH  TAA  ++ L ++G + E +
Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352

Query: 262 TK 267
            K
Sbjct: 353 KK 354


>AY422002-1|AAR31180.1|  525|Homo sapiens cytochrome P450 4V2
           protein.
          Length = 525

 Score = 95.5 bits (227), Expect = 2e-19
 Identities = 51/138 (36%), Positives = 75/138 (54%)
 Frame = +3

Query: 240 GYSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQE 419
           G +  +Q KV  ELD +FG SDRP T +D  +++YLE  + ETLRL+P VP+ AR V+++
Sbjct: 346 GSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSED 405

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLG 599
             +   G ++  GT  VI  Y LHR P  +           F              F  G
Sbjct: 406 CEVA--GYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 463

Query: 600 PRSCVGRKYAMLKLKVIL 653
           PR+C+G+K+A+++ K IL
Sbjct: 464 PRNCIGQKFAVMEEKTIL 481



 Score = 56.8 bits (131), Expect = 7e-08
 Identities = 29/62 (46%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + KR AFLDLLL  +   G  +S E+I+E+VDT MFEGH  TAA  ++ L ++G + E +
Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352

Query: 262 TK 267
            K
Sbjct: 353 KK 354


>AK126473-1|BAC86562.1|  503|Homo sapiens protein ( Homo sapiens
           cDNA FLJ44509 fis, clone UTERU3001585, weakly  similar
           to Cytochrome P450 4c3 (EC 1.14.-.-). ).
          Length = 503

 Score = 95.5 bits (227), Expect = 2e-19
 Identities = 51/138 (36%), Positives = 75/138 (54%)
 Frame = +3

Query: 240 GYSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQE 419
           G +  +Q KV  ELD +FG SDRP T +D  +++YLE  + ETLRL+P VP+ AR V+++
Sbjct: 324 GSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSED 383

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLG 599
             +   G ++  GT  VI  Y LHR P  +           F              F  G
Sbjct: 384 CEVA--GYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 441

Query: 600 PRSCVGRKYAMLKLKVIL 653
           PR+C+G+K+A+++ K IL
Sbjct: 442 PRNCIGQKFAVMEEKTIL 459



 Score = 56.8 bits (131), Expect = 7e-08
 Identities = 29/62 (46%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + KR AFLDLLL  +   G  +S E+I+E+VDT MFEGH  TAA  ++ L ++G + E +
Sbjct: 271 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 330

Query: 262 TK 267
            K
Sbjct: 331 KK 332


>AK122600-1|BAC85487.1|  525|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16007 fis, clone KIDNE2006580, weakly  similar
           to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
          Length = 525

 Score = 95.5 bits (227), Expect = 2e-19
 Identities = 51/138 (36%), Positives = 75/138 (54%)
 Frame = +3

Query: 240 GYSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQE 419
           G +  +Q KV  ELD +FG SDRP T +D  +++YLE  + ETLRL+P VP+ AR V+++
Sbjct: 346 GSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSED 405

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLG 599
             +   G ++  GT  VI  Y LHR P  +           F              F  G
Sbjct: 406 CEVA--GYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 463

Query: 600 PRSCVGRKYAMLKLKVIL 653
           PR+C+G+K+A+++ K IL
Sbjct: 464 PRNCIGQKFAVMEEKTIL 481



 Score = 56.8 bits (131), Expect = 7e-08
 Identities = 29/62 (46%), Positives = 41/62 (66%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLDLLLE-SSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + KR AFLDLLL  +   G  +S E+I+E+VDT MFEGH  TAA  ++ L ++G + E +
Sbjct: 293 KNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQ 352

Query: 262 TK 267
            K
Sbjct: 353 KK 354


>D26480-1|BAA05490.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 48/144 (33%), Positives = 83/144 (57%), Gaps = 5/144 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D   + +L  C+ E+LRL+PPVP+I+R V Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P V+    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAVW---PDPEVYDPFR-FDPENIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+G+ +AM ++KV+L     +F
Sbjct: 466 RNCIGQTFAMAEMKVVLALTLLRF 489



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>BC067439-1|AAH67439.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 48/144 (33%), Positives = 83/144 (57%), Gaps = 5/144 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D   + +L  C+ E+LRL+PPVP+I+R V Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P V+    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAVW---PDPEVYDPFR-FDPENIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+G+ +AM ++KV+L     +F
Sbjct: 466 RNCIGQTFAMAEMKVVLALTLLRF 489



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>BC067437-1|AAH67437.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 48/144 (33%), Positives = 83/144 (57%), Gaps = 5/144 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D   + +L  C+ E+LRL+PPVP+I+R V Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P V+    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAVW---PDPEVYDPFR-FDPENIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+G+ +AM ++KV+L     +F
Sbjct: 466 RNCIGQTFAMAEMKVVLALTLLRF 489



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AF467894-1|AAL67578.1|  520|Homo sapiens cytochrome P450, subfamily
           IVF, polypeptide 2 protein.
          Length = 520

 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 48/144 (33%), Positives = 83/144 (57%), Gaps = 5/144 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D   + +L  C+ E+LRL+PPVP+I+R V Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P V+    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAVW---PDPEVYDPFR-FDPENIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+G+ +AM ++KV+L     +F
Sbjct: 466 RNCIGQTFAMAEMKVVLALTLLRF 489



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AC005336-1|AAC27730.1|  520|Homo sapiens CYP4F2 protein.
          Length = 520

 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 48/144 (33%), Positives = 83/144 (57%), Gaps = 5/144 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D   + +L  C+ E+LRL+PPVP+I+R V Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P V+    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAVW---PDPEVYDPFR-FDPENIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+G+ +AM ++KV+L     +F
Sbjct: 466 RNCIGQTFAMAEMKVVLALTLLRF 489



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>U02388-1|AAC50052.2|  520|Homo sapiens cytochrome P450 4F2 protein.
          Length = 520

 Score = 84.6 bits (200), Expect = 3e-16
 Identities = 47/144 (32%), Positives = 83/144 (57%), Gaps = 5/144 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D   + +L  C+ E+LR++PPVP+I+R V Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRVHPPVPVISRHVTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P V+    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAVW---PDPEVYDPFR-FDPENIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+G+ +AM ++KV+L     +F
Sbjct: 466 RNCIGQTFAMAEMKVVLALTLLRF 489



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 26/62 (41%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+  S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASVLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>BC067440-1|AAH67440.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score = 84.6 bits (200), Expect = 3e-16
 Identities = 47/144 (32%), Positives = 83/144 (57%), Gaps = 5/144 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D   + +L  C+ E+LRL+PPVP+I+R V Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P ++    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAMW---PDPEVYDPFR-FDPENIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+G+ +AM ++KV+L     +F
Sbjct: 466 RNCIGQTFAMAEMKVVLALTLLRF 489



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AB015306-1|BAA75823.1|  520|Homo sapiens Leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score = 84.6 bits (200), Expect = 3e-16
 Identities = 47/144 (32%), Positives = 83/144 (57%), Gaps = 5/144 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D   + +L  C+ E+LRL+PPVP+I+R V Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P ++    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAMW---PDPEVYDPFR-FDPENIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+G+ +AM ++KV+L     +F
Sbjct: 466 RNCIGQTFAMAEMKVVLALTLLRF 489



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>L04751-1|AAA58436.1|  519|Homo sapiens cytochrome P450 protein.
          Length = 519

 Score = 81.8 bits (193), Expect = 2e-15
 Identities = 48/144 (33%), Positives = 78/144 (54%), Gaps = 4/144 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    N  +   FR  P +     + L F  G R+C+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW---PNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCI 458

Query: 615 GRKYAMLKLKV---ILFYNFEKFP 677
           G+++AM +LKV   +    FE  P
Sbjct: 459 GKQFAMNELKVATALTLLRFELLP 482



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346


>D26481-1|BAA05491.1|  519|Homo sapiens fatty acids
           omega-hydroxylase protein.
          Length = 519

 Score = 81.8 bits (193), Expect = 2e-15
 Identities = 48/144 (33%), Positives = 78/144 (54%), Gaps = 4/144 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    N  +   FR  P +     + L F  G R+C+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW---PNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCI 458

Query: 615 GRKYAMLKLKV---ILFYNFEKFP 677
           G+++AM +LKV   +    FE  P
Sbjct: 459 GKQFAMNELKVATALTLLRFELLP 482



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346


>AY369778-1|AAQ56847.1|  519|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 11 protein.
          Length = 519

 Score = 81.8 bits (193), Expect = 2e-15
 Identities = 48/144 (33%), Positives = 78/144 (54%), Gaps = 4/144 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    N  +   FR  P +     + L F  G R+C+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW---PNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCI 458

Query: 615 GRKYAMLKLKV---ILFYNFEKFP 677
           G+++AM +LKV   +    FE  P
Sbjct: 459 GKQFAMNELKVATALTLLRFELLP 482



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346


>AY280371-1|AAQ21367.1|  519|Homo sapiens cytochrome P450 4A22K
           protein.
          Length = 519

 Score = 81.8 bits (193), Expect = 2e-15
 Identities = 48/144 (33%), Positives = 78/144 (54%), Gaps = 4/144 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    N  +   FR  P +     + L F  G R+C+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW---PNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCI 458

Query: 615 GRKYAMLKLKV---ILFYNFEKFP 677
           G+++AM +LKV   +    FE  P
Sbjct: 459 GKQFAMNQLKVARALTLLRFELLP 482



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346


>AL731892-3|CAH72778.1|  519|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 11 protein.
          Length = 519

 Score = 81.8 bits (193), Expect = 2e-15
 Identities = 48/144 (33%), Positives = 78/144 (54%), Gaps = 4/144 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    N  +   FR  P +     + L F  G R+C+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW---PNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCI 458

Query: 615 GRKYAMLKLKV---ILFYNFEKFP 677
           G+++AM +LKV   +    FE  P
Sbjct: 459 GKQFAMNELKVATALTLLRFELLP 482



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346


>D13705-1|BAA02864.1|  521|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 521

 Score = 81.4 bits (192), Expect = 3e-15
 Identities = 45/131 (34%), Positives = 74/131 (56%), Gaps = 1/131 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 345 QERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 402

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    N  +   FR  P +     + L F  G R+C+
Sbjct: 403 GRSLPKGIMVLLSIYGLHHNPKVW---PNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCI 459

Query: 615 GRKYAMLKLKV 647
           G+++AM +LKV
Sbjct: 460 GKQFAMNELKV 470



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 286 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 345

Query: 262 TK 267
            +
Sbjct: 346 ER 347


>AY792513-1|AAV40834.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 3 protein.
          Length = 520

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 46/144 (31%), Positives = 82/144 (56%), Gaps = 5/144 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D  ++ +L  C+ E+LRL+PPVP ++R   Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P V+    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAVW---PDPEVYDPFR-FDPKNIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+G+ +AM ++KV+L     +F
Sbjct: 466 RNCIGQAFAMAEMKVVLGLTLLRF 489



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AF054821-1|AAC08589.1|  520|Homo sapiens cytochrome P-450 protein.
          Length = 520

 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 46/144 (31%), Positives = 82/144 (56%), Gaps = 5/144 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D  ++ +L  C+ E+LRL+PPVP ++R   Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P V+    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAVW---PDPEVYDPFR-FDPKNIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+G+ +AM ++KV+L     +F
Sbjct: 466 RNCIGQAFAMAEMKVVLGLTLLRF 489



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>D12620-1|BAA02144.1|  520|Homo sapiens cytochrome P-450LTBV
           protein.
          Length = 520

 Score = 80.6 bits (190), Expect = 5e-15
 Identities = 45/137 (32%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D  ++ +L  C+ E+LRL+PPVP ++R   Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P V+    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAVW---PDPEVYDPFR-FDPKNIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVIL 653
           R+C+G+ +AM ++KV+L
Sbjct: 466 RNCIGQAFAMAEMKVVL 482



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AL135960-9|CAI19737.1|  519|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 22 protein.
          Length = 519

 Score = 80.6 bits (190), Expect = 5e-15
 Identities = 48/144 (33%), Positives = 78/144 (54%), Gaps = 4/144 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    NL +    R  P +     + L F  G R+C+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW---PNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCI 458

Query: 615 GRKYAMLKLKV---ILFYNFEKFP 677
           G+++AM +LKV   +    FE  P
Sbjct: 459 GKQFAMNQLKVARALTLLRFELLP 482



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346


>AF208532-1|AAF76722.1|  519|Homo sapiens fatty acid
           omega-hydroxylase CYP4A11 protein.
          Length = 519

 Score = 80.6 bits (190), Expect = 5e-15
 Identities = 48/144 (33%), Positives = 78/144 (54%), Gaps = 4/144 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    NL +    R  P +     + L F  G R+C+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW---PNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCI 458

Query: 615 GRKYAMLKLKV---ILFYNFEKFP 677
           G+++AM +LKV   +    FE  P
Sbjct: 459 GKQFAMNQLKVARALTLLRFELLP 482



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346


>AB002461-1|BAA25991.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score = 80.6 bits (190), Expect = 5e-15
 Identities = 45/137 (32%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D  ++ +L  C+ E+LRL+PPVP ++R   Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P V+    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAVW---PDPEVYDPFR-FDPKNIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVIL 653
           R+C+G+ +AM ++KV+L
Sbjct: 466 RNCIGQAFAMAEMKVVL 482



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AB002454-1|BAA25990.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score = 80.6 bits (190), Expect = 5e-15
 Identities = 45/137 (32%), Positives = 80/137 (58%), Gaps = 5/137 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D  ++ +L  C+ E+LRL+PPVP ++R   Q+I LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I+ +  H  P V+    +  +   FR   P +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIICLISVFGTHHNPAVW---PDPEVYDPFR-FDPKNIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVIL 653
           R+C+G+ +AM ++KV+L
Sbjct: 466 RNCIGQAFAMAEMKVVL 482



 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AF525488-1|AAO16078.1|  519|Homo sapiens cytochrome P450, subfamily
           IVA, polypeptide 11 protein.
          Length = 519

 Score = 80.2 bits (189), Expect = 6e-15
 Identities = 47/144 (32%), Positives = 78/144 (54%), Gaps = 4/144 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRL+PPVP I R+++  +T P +
Sbjct: 344 QERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    N  +   FR  P +     + L F  G R+C+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW---PNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCI 458

Query: 615 GRKYAMLKLKV---ILFYNFEKFP 677
           G+++AM +LKV   +    FE  P
Sbjct: 459 GKQFAMNELKVATALTLLRFELLP 482



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346


>X16699-1|CAA34672.1|  511|Homo sapiens protein ( Human mRNA for
           cytochrome P-450HP. ).
          Length = 511

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 338 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 395

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 396 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 452

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 453 CIGQQFAMSEMKVV 466



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 338


>J02871-1|AAA35712.1|  511|Homo sapiens protein ( Human lung
           cytochrome P450 (IV subfamily) BI protein, complete cds.
           ).
          Length = 511

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 338 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 395

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 396 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 452

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 453 CIGQQFAMSEMKVV 466



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 338


>DQ518907-1|ABF47106.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 338 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 395

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 396 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 452

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 453 CIGQQFAMSEMKVV 466



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 338


>BC017758-1|AAH17758.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 339 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 396

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 397 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 453

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 454 CIGQQFAMSEMKVV 467



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 281 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 339


>AY151049-1|AAN72312.1|  497|Homo sapiens pulmonary cytochrome P450
           4B1 variant protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 324 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 381

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 382 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 438

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 439 CIGQQFAMSEMKVV 452



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 266 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 324


>AY151048-1|AAN72311.1|  512|Homo sapiens pulmonary cytochrome P450
           4B1 protein.
          Length = 512

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 339 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 396

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 397 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 453

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 454 CIGQQFAMSEMKVV 467



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 281 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 339


>AY064486-1|AAL57721.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 338 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 395

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 396 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 452

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 453 CIGQQFAMSEMKVV 466



 Score = 52.8 bits (121), Expect = 1e-06
 Identities = 23/59 (38%), Positives = 39/59 (66%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T  G S+FL  M ++ E++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTGGISWFLYCMALYPEHQ 338


>AY064485-1|AAL57720.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 338 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 395

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 396 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 452

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 453 CIGQQFAMSEMKVV 466



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 338


>AL593856-7|CAI16982.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 339 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 396

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 397 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 453

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 454 CIGQQFAMSEMKVV 467



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 281 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 339


>AL593856-6|CAI16981.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 338 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 395

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 396 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 452

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 453 CIGQQFAMSEMKVV 466



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 338


>AL593856-5|CAI16983.1|  497|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 324 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 381

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 382 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 438

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 439 CIGQQFAMSEMKVV 452



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 266 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 324


>AL356793-4|CAI22557.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 339 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 396

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 397 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 453

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 454 CIGQQFAMSEMKVV 467



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 281 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 339


>AL356793-3|CAI22559.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 338 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 395

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 396 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 452

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 453 CIGQQFAMSEMKVV 466



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 338


>AL356793-2|CAI22558.1|  497|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 497

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 324 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 381

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 382 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 438

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 439 CIGQQFAMSEMKVV 452



 Score = 53.2 bits (122), Expect = 9e-07
 Identities = 23/59 (38%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  M ++ E++
Sbjct: 266 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQ 324


>AF491285-1|AAM09532.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 45/134 (33%), Positives = 77/134 (57%), Gaps = 3/134 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  EE+ +I GD D    + D  +M YL  C+ E+ RLYPPVP + RQ+++ +T   +
Sbjct: 338 QHRCREEVREILGDQDF-FQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTF-VD 395

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRS 608
           G+ +PAG+ + +  Y LHR   V+   ++  +L  +T   +       M    F  GPR+
Sbjct: 396 GRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMP---FSAGPRN 452

Query: 609 CVGRKYAMLKLKVI 650
           C+G+++AM ++KV+
Sbjct: 453 CIGQQFAMSEMKVV 466



 Score = 51.6 bits (118), Expect = 3e-06
 Identities = 22/59 (37%), Positives = 40/59 (67%), Gaps = 1/59 (1%)
 Frame = +1

Query: 88  KKRLAFLDLLLES-SQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++ L FLD+LL +  +  + +SD +++ +VDT MFEGH  T +G S+FL  + ++ E++
Sbjct: 280 RRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCIALYPEHQ 338


>AF133298-1|AAD49566.1|  520|Homo sapiens cytochrome P450 protein.
          Length = 520

 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 44/144 (30%), Positives = 79/144 (54%), Gaps = 5/144 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D + + + + D  ++ +L  CL E+LRL+PP+P  AR   Q++ LP 
Sbjct: 351 QERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           + + IP G    I  + +H  P V+    +  +   FR   P +   RS +    F  GP
Sbjct: 410 DSRVIPKGNVCNINIFAIHHNPSVW---PDPEVYDPFR-FDPENAQKRSPMAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+G+K+AM ++KV+L     +F
Sbjct: 466 RNCIGQKFAMAEMKVVLALTLLRF 489



 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 26/62 (41%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   ++G  +SDE+I+ + DT MF GH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>S67581-1|AAB29503.1|  591|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 591

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 47/144 (32%), Positives = 77/144 (53%), Gaps = 4/144 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    N  +    R  P +     + L F  G R+C+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW---PNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCI 458

Query: 615 GRKYAMLKLKV---ILFYNFEKFP 677
           G+++AM +LKV   +    FE  P
Sbjct: 459 GKQFAMNELKVATALTLLRFELLP 482



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346


>S67580-1|AAB29502.1|  519|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 519

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 47/144 (32%), Positives = 77/144 (53%), Gaps = 4/144 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    N  +    R  P +     + L F  G R+C+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW---PNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCI 458

Query: 615 GRKYAMLKLKV---ILFYNFEKFP 677
           G+++AM +LKV   +    FE  P
Sbjct: 459 GKQFAMNELKVATALTLLRFELLP 482



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346


>BC035350-1|AAH35350.1|  524|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 12 protein.
          Length = 524

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 46/137 (33%), Positives = 78/137 (56%), Gaps = 5/137 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D D + + + D  ++ +L  C+ E+LRL+PP P I+R   Q+I LP 
Sbjct: 351 QERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G T +I    +H  P V+    +  +   FR   P +   RS L    F  GP
Sbjct: 410 DGRVIPKGITCLIDIIGVHHNPTVW---PDPEVYDPFR-FDPENSKGRSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVIL 653
           R+C+G+ +AM ++KV+L
Sbjct: 466 RNCIGQAFAMAEMKVVL 482



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G A+SDE+I+ + DT MF GH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AY358977-1|AAQ89336.1|  524|Homo sapiens CYP4F12 protein.
          Length = 524

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 46/137 (33%), Positives = 78/137 (56%), Gaps = 5/137 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D D + + + D  ++ +L  C+ E+LRL+PP P I+R   Q+I LP 
Sbjct: 351 QERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G T +I    +H  P V+    +  +   FR   P +   RS L    F  GP
Sbjct: 410 DGRVIPKGITCLIDIIGVHHNPTVW---PDPEVYDPFR-FDPENSKGRSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVIL 653
           R+C+G+ +AM ++KV+L
Sbjct: 466 RNCIGQAFAMAEMKVVL 482



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G A+SDE+I+ + DT MF GH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AY008841-1|AAG33247.1|  524|Homo sapiens cytochrome P450 isoform
           4F12 protein.
          Length = 524

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 46/137 (33%), Positives = 78/137 (56%), Gaps = 5/137 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D D + + + D  ++ +L  C+ E+LRL+PP P I+R   Q+I LP 
Sbjct: 351 QERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G T +I    +H  P V+    +  +   FR   P +   RS L    F  GP
Sbjct: 410 DGRVIPKGITCLIDIIGVHHNPTVW---PDPEVYDPFR-FDPENSKGRSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVIL 653
           R+C+G+ +AM ++KV+L
Sbjct: 466 RNCIGQAFAMAEMKVVL 482



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G A+SDE+I+ + DT MF GH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AC004523-1|AAC11543.1|  458|Homo sapiens F22329_1 protein.
          Length = 458

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 46/137 (33%), Positives = 78/137 (56%), Gaps = 5/137 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D D + + + D  ++ +L  C+ E+LRL+PP P I+R   Q+I LP 
Sbjct: 285 QERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLP- 343

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G T +I    +H  P V+    +  +   FR   P +   RS L    F  GP
Sbjct: 344 DGRVIPKGITCLIDIIGVHHNPTVW---PDPEVYDPFR-FDPENSKGRSPLAFIPFSAGP 399

Query: 603 RSCVGRKYAMLKLKVIL 653
           R+C+G+ +AM ++KV+L
Sbjct: 400 RNCIGQAFAMAEMKVVL 416



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G A+SDE+I+ + DT MF GH  TA+G S+ L  +  H EY+
Sbjct: 226 KSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQ 285

Query: 262 TK 267
            +
Sbjct: 286 ER 287


>AB035131-1|BAB18270.1|  524|Homo sapiens cytochrome P450 protein.
          Length = 524

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 46/137 (33%), Positives = 78/137 (56%), Gaps = 5/137 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D D + + + D  ++ +L  C+ E+LRL+PP P I+R   Q+I LP 
Sbjct: 351 QERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G T +I    +H  P V+    +  +   FR   P +   RS L    F  GP
Sbjct: 410 DGRVIPKGITCLIDIIGVHHNPTVW---PDPEVYDPFR-FDPENSKGRSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVIL 653
           R+C+G+ +AM ++KV+L
Sbjct: 466 RNCIGQAFAMAEMKVVL 482



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G A+SDE+I+ + DT MF GH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AB035130-1|BAB18269.1|  524|Homo sapiens cytochrome P450 protein.
          Length = 524

 Score = 78.6 bits (185), Expect = 2e-14
 Identities = 46/137 (33%), Positives = 78/137 (56%), Gaps = 5/137 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSD-RPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D D + + + D  ++ +L  C+ E+LRL+PP P I+R   Q+I LP 
Sbjct: 351 QERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G T +I    +H  P V+    +  +   FR   P +   RS L    F  GP
Sbjct: 410 DGRVIPKGITCLIDIIGVHHNPTVW---PDPEVYDPFR-FDPENSKGRSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVIL 653
           R+C+G+ +AM ++KV+L
Sbjct: 466 RNCIGQAFAMAEMKVVL 482



 Score = 55.6 bits (128), Expect = 2e-07
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G A+SDE+I+ + DT MF GH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AY280372-1|AAQ21368.1|  519|Homo sapiens cytochrome P450 4A22
           protein.
          Length = 519

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 47/144 (32%), Positives = 77/144 (53%), Gaps = 4/144 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCV 614
           G+ +P G  ++++ Y LH  P V+    N  +    R  P +     + L F  G R+C+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW---PNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCI 458

Query: 615 GRKYAMLKLKV---ILFYNFEKFP 677
           G+++AM +LKV   +    FE  P
Sbjct: 459 GKQFAMNQLKVARALTLLRFELLP 482



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346


>BC093896-1|AAH93896.1|  531|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 22 protein.
          Length = 531

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 39/140 (27%), Positives = 72/140 (51%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K  EE+ ++  G     + + D  ++ +   C+ E+LR YPPV +++RQ  ++I LP 
Sbjct: 358 QEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLP- 416

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G+ IP G   +++ Y  H  P V+             + P     +    F  GPR+C+
Sbjct: 417 DGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCI 476

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+ +AM +L+V++     +F
Sbjct: 477 GQSFAMAELRVVVALTLLRF 496



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           Q K L F+D LLL   + G  +SDE+I+ + DT MFEGH  T++G S+ L  +  + EY+
Sbjct: 299 QGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQ 358

Query: 262 TK 267
            K
Sbjct: 359 EK 360


>BC093894-1|AAH93894.1|  531|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 22 protein.
          Length = 531

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 39/140 (27%), Positives = 72/140 (51%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K  EE+ ++  G     + + D  ++ +   C+ E+LR YPPV +++RQ  ++I LP 
Sbjct: 358 QEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLP- 416

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G+ IP G   +++ Y  H  P V+             + P     +    F  GPR+C+
Sbjct: 417 DGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCI 476

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+ +AM +L+V++     +F
Sbjct: 477 GQSFAMAELRVVVALTLLRF 496



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           Q K L F+D LLL   + G  +SDE+I+ + DT MFEGH  T++G S+ L  +  + EY+
Sbjct: 299 QGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQ 358

Query: 262 TK 267
            K
Sbjct: 359 EK 360


>BC069351-1|AAH69351.1|  531|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 22 protein.
          Length = 531

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 39/140 (27%), Positives = 72/140 (51%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K  EE+ ++  G     + + D  ++ +   C+ E+LR YPPV +++RQ  ++I LP 
Sbjct: 358 QEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLP- 416

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G+ IP G   +++ Y  H  P V+             + P     +    F  GPR+C+
Sbjct: 417 DGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCI 476

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+ +AM +L+V++     +F
Sbjct: 477 GQSFAMAELRVVVALTLLRF 496



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           Q K L F+D LLL   + G  +SDE+I+ + DT MFEGH  T++G S+ L  +  + EY+
Sbjct: 299 QGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQ 358

Query: 262 TK 267
            K
Sbjct: 359 EK 360


>AK096820-1|BAC04868.1|  531|Homo sapiens protein ( Homo sapiens
           cDNA FLJ39501 fis, clone PROST2016980, moderately
           similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
          Length = 531

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 39/140 (27%), Positives = 72/140 (51%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIF-GDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K  EE+ ++  G     + + D  ++ +   C+ E+LR YPPV +++RQ  ++I LP 
Sbjct: 358 QEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLP- 416

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G+ IP G   +++ Y  H  P V+             + P     +    F  GPR+C+
Sbjct: 417 DGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCI 476

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+ +AM +L+V++     +F
Sbjct: 477 GQSFAMAELRVVVALTLLRF 496



 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           Q K L F+D LLL   + G  +SDE+I+ + DT MFEGH  T++G S+ L  +  + EY+
Sbjct: 299 QGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQ 358

Query: 262 TK 267
            K
Sbjct: 359 EK 360


>BC028102-1|AAH28102.1|  509|Homo sapiens cytochrome P450, family 4,
           subfamily X, polypeptide 1 protein.
          Length = 509

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 42/132 (31%), Positives = 70/132 (53%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  I GD    +T+    EM Y   C+ ET RL P VP I+R +++ +T P +
Sbjct: 339 QERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP-D 396

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVG 617
           G  +PAG T+V++ + LH  P V++           +             F  G R+C+G
Sbjct: 397 GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 456

Query: 618 RKYAMLKLKVIL 653
           +++AM++LKV +
Sbjct: 457 QEFAMIELKVTI 468



 Score = 40.7 bits (91), Expect = 0.005
 Identities = 17/31 (54%), Positives = 21/31 (67%)
 Frame = +2

Query: 512 NPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           NP  FDP  F  E S  RH YA++PFSAG++
Sbjct: 422 NPKVFDPLRFSQENSDQRHPYAYLPFSAGSR 452



 Score = 38.3 bits (85), Expect = 0.026
 Identities = 18/62 (29%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++K   FLD++L +  +SG + SD ++  +V T +  GH   AA  S+ L  + ++ E++
Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339

Query: 262 TK 267
            +
Sbjct: 340 ER 341


>AY358537-1|AAQ88901.1|  509|Homo sapiens EFSW1929 protein.
          Length = 509

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 42/132 (31%), Positives = 70/132 (53%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  I GD    +T+    EM Y   C+ ET RL P VP I+R +++ +T P +
Sbjct: 339 QERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP-D 396

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVG 617
           G  +PAG T+V++ + LH  P V++           +             F  G R+C+G
Sbjct: 397 GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 456

Query: 618 RKYAMLKLKVIL 653
           +++AM++LKV +
Sbjct: 457 QEFAMIELKVTI 468



 Score = 40.7 bits (91), Expect = 0.005
 Identities = 17/31 (54%), Positives = 21/31 (67%)
 Frame = +2

Query: 512 NPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           NP  FDP  F  E S  RH YA++PFSAG++
Sbjct: 422 NPKVFDPLRFSQENSDQRHPYAYLPFSAGSR 452



 Score = 38.3 bits (85), Expect = 0.026
 Identities = 18/62 (29%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++K   FLD++L +  +SG + SD ++  +V T +  GH   AA  S+ L  + ++ E++
Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339

Query: 262 TK 267
            +
Sbjct: 340 ER 341


>AM040940-1|CAJ13826.1|  509|Homo sapiens cytochrome P450 protein.
          Length = 509

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 42/132 (31%), Positives = 70/132 (53%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  I GD    +T+    EM Y   C+ ET RL P VP I+R +++ +T P +
Sbjct: 339 QERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP-D 396

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVG 617
           G  +PAG T+V++ + LH  P V++           +             F  G R+C+G
Sbjct: 397 GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 456

Query: 618 RKYAMLKLKVIL 653
           +++AM++LKV +
Sbjct: 457 QEFAMIELKVTI 468



 Score = 40.7 bits (91), Expect = 0.005
 Identities = 17/31 (54%), Positives = 21/31 (67%)
 Frame = +2

Query: 512 NPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           NP  FDP  F  E S  RH YA++PFSAG++
Sbjct: 422 NPKVFDPLRFSQENSDQRHPYAYLPFSAGSR 452



 Score = 38.3 bits (85), Expect = 0.026
 Identities = 18/62 (29%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++K   FLD++L +  +SG + SD ++  +V T +  GH   AA  S+ L  + ++ E++
Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339

Query: 262 TK 267
            +
Sbjct: 340 ER 341


>AL450996-1|CAH71035.1|  509|Homo sapiens cytochrome P450, family 4,
           subfamily X, polypeptide 1 protein.
          Length = 509

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 42/132 (31%), Positives = 70/132 (53%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  I GD    +T+    EM Y   C+ ET RL P VP I+R +++ +T P +
Sbjct: 339 QERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP-D 396

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVG 617
           G  +PAG T+V++ + LH  P V++           +             F  G R+C+G
Sbjct: 397 GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 456

Query: 618 RKYAMLKLKVIL 653
           +++AM++LKV +
Sbjct: 457 QEFAMIELKVTI 468



 Score = 40.7 bits (91), Expect = 0.005
 Identities = 17/31 (54%), Positives = 21/31 (67%)
 Frame = +2

Query: 512 NPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           NP  FDP  F  E S  RH YA++PFSAG++
Sbjct: 422 NPKVFDPLRFSQENSDQRHPYAYLPFSAGSR 452



 Score = 38.3 bits (85), Expect = 0.026
 Identities = 18/62 (29%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++K   FLD++L +  +SG + SD ++  +V T +  GH   AA  S+ L  + ++ E++
Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339

Query: 262 TK 267
            +
Sbjct: 340 ER 341


>AK131355-1|BAD18508.1|  508|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16384 fis, clone TLIVE2007607, weakly  similar
           to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 508

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 42/132 (31%), Positives = 70/132 (53%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  I GD    +T+    EM Y   C+ ET RL P VP I+R +++ +T P +
Sbjct: 338 QERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP-D 395

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVG 617
           G  +PAG T+V++ + LH  P V++           +             F  G R+C+G
Sbjct: 396 GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 455

Query: 618 RKYAMLKLKVIL 653
           +++AM++LKV +
Sbjct: 456 QEFAMIELKVTI 467



 Score = 40.7 bits (91), Expect = 0.005
 Identities = 17/31 (54%), Positives = 21/31 (67%)
 Frame = +2

Query: 512 NPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           NP  FDP  F  E S  RH YA++PFSAG++
Sbjct: 421 NPKVFDPLRFSQENSDQRHPYAYLPFSAGSR 451



 Score = 38.3 bits (85), Expect = 0.026
 Identities = 18/62 (29%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++K   FLD++L +  +SG + SD ++  +V T +  GH   AA  S+ L  + ++ E++
Sbjct: 279 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 338

Query: 262 TK 267
            +
Sbjct: 339 ER 340


>AK098065-1|BAC05226.1|  509|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
           CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 509

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 42/132 (31%), Positives = 70/132 (53%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  I GD    +T+    EM Y   C+ ET RL P VP I+R +++ +T P +
Sbjct: 339 QERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP-D 396

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVG 617
           G  +PAG T+V++ + LH  P V++           +             F  G R+C+G
Sbjct: 397 GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 456

Query: 618 RKYAMLKLKVIL 653
           +++AM++LKV +
Sbjct: 457 QEFAMIELKVTI 468



 Score = 40.7 bits (91), Expect = 0.005
 Identities = 17/31 (54%), Positives = 21/31 (67%)
 Frame = +2

Query: 512 NPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           NP  FDP  F  E S  RH YA++PFSAG++
Sbjct: 422 NPKVFDPLRFSQENSDQRHPYAYLPFSAGSR 452



 Score = 38.3 bits (85), Expect = 0.026
 Identities = 18/62 (29%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++K   FLD++L +  +SG + SD ++  +V T +  GH   AA  S+ L  + ++ E++
Sbjct: 280 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 339

Query: 262 TK 267
            +
Sbjct: 340 ER 341


>AK091806-1|BAC03751.1|  444|Homo sapiens protein ( Homo sapiens
           cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
           CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 444

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 42/132 (31%), Positives = 70/132 (53%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  I GD    +T+    EM Y   C+ ET RL P VP I+R +++ +T P +
Sbjct: 274 QERCREEVRGILGDGSS-ITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFP-D 331

Query: 438 GKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVG 617
           G  +PAG T+V++ + LH  P V++           +             F  G R+C+G
Sbjct: 332 GCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 391

Query: 618 RKYAMLKLKVIL 653
           +++AM++LKV +
Sbjct: 392 QEFAMIELKVTI 403



 Score = 40.7 bits (91), Expect = 0.005
 Identities = 17/31 (54%), Positives = 21/31 (67%)
 Frame = +2

Query: 512 NPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           NP  FDP  F  E S  RH YA++PFSAG++
Sbjct: 357 NPKVFDPLRFSQENSDQRHPYAYLPFSAGSR 387



 Score = 38.3 bits (85), Expect = 0.026
 Identities = 18/62 (29%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLDLLLESS-QSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           ++K   FLD++L +  +SG + SD ++  +V T +  GH   AA  S+ L  + ++ E++
Sbjct: 215 KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALNPEHQ 274

Query: 262 TK 267
            +
Sbjct: 275 ER 276


>AF280109-1|AAG33010.1|  504|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 504

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 41/141 (29%), Positives = 72/141 (51%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDI-IMRSCLFQLGPRSC 611
           NG  IP G  +++  Y LH  P  +         + F       I + R   F  GPR+C
Sbjct: 384 NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNC 443

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A+  +K+ +    + F
Sbjct: 444 IGMRFALTNIKLAVIRALQNF 464


>AC011904-5|AAS07394.1|  504|Homo sapiens unknown protein.
          Length = 504

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 41/141 (29%), Positives = 72/141 (51%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDI-IMRSCLFQLGPRSC 611
           NG  IP G  +++  Y LH  P  +         + F       I + R   F  GPR+C
Sbjct: 384 NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNC 443

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A+  +K+ +    + F
Sbjct: 444 IGMRFALTNIKLAVIRALQNF 464


>AF236085-1|AAG15889.1|  524|Homo sapiens CYP4F11 protein.
          Length = 524

 Score = 73.7 bits (173), Expect = 6e-13
 Identities = 47/151 (31%), Positives = 83/151 (54%), Gaps = 8/151 (5%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDR-PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D +   + + D  ++ +L  C+ E+LRL+PPVP+I+R   Q+  LP 
Sbjct: 351 QEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I    +H  P V+    +  +   FR     +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIVCLINIIGIHYNPTVW---PDPEVYDPFR-FNQENIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVIL---FYNFEKFPSNI 686
           R+C+G+ +AM ++KV+L     +F   P++I
Sbjct: 466 RNCIGQAFAMAEMKVVLALTLLHFRILPTHI 496



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 27/60 (45%), Positives = 38/60 (63%), Gaps = 1/60 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351


>BC016853-1|AAH16853.1|  524|Homo sapiens CYP4F11 protein protein.
          Length = 524

 Score = 73.3 bits (172), Expect = 7e-13
 Identities = 44/137 (32%), Positives = 77/137 (56%), Gaps = 5/137 (3%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDR-PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q++  +E+ ++  D +   + + D  ++ +L  C+ E+LRL+PPVP+I+R   Q+  LP 
Sbjct: 351 QEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLP- 409

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL----FQLGP 602
           +G+ IP G   +I    +H  P V+    +  +   FR     +I  RS L    F  GP
Sbjct: 410 DGRVIPKGIVCLINIIGIHYNPTVW---PDPEVYDPFR-FNQENIKERSPLAFIPFSAGP 465

Query: 603 RSCVGRKYAMLKLKVIL 653
           R+C+G+ +AM ++KV+L
Sbjct: 466 RNCIGQAFAMAEMKVVL 482



 Score = 56.0 bits (129), Expect = 1e-07
 Identities = 27/60 (45%), Positives = 38/60 (63%), Gaps = 1/60 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351


>AY390424-1|AAQ92352.1|  503|Homo sapiens cytochrome P450 CYP3A43.3
           protein.
          Length = 503

 Score = 73.3 bits (172), Expect = 7e-13
 Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +  
Sbjct: 327 VQQKLQEEIDAVLANK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  +++  Y LH  P  + + +       S +N    D + R   F  GPR+C
Sbjct: 384 NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSID-LYRYIPFGAGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A+  +K+ +    + F
Sbjct: 443 IGMRFALTNIKLAVIRALQNF 463


>AL135960-10|CAI19736.1|  421|Homo sapiens cytochrome P450, family
           4, subfamily A, polypeptide 22 protein.
          Length = 421

 Score = 73.3 bits (172), Expect = 7e-13
 Identities = 42/119 (35%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
 Frame = +3

Query: 333 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQ 512
           +M Y   C+ E LRLYPPVP I R+++  +T P +G+ +P G  ++++ Y LH  P V+ 
Sbjct: 270 QMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-DGRSLPKGIMVLLSIYGLHHNPKVW- 327

Query: 513 IQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSCVGRKYAMLKLKV---ILFYNFEKFP 677
              NL +    R  P +     + L F  G R+C+G+++AM +LKV   +    FE  P
Sbjct: 328 --PNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLP 384


>M18907-1|AAA35745.1|  503|Homo sapiens protein ( Human P450 mRNA
           encoding nifedipine oxidase, complete cds. ).
          Length = 503

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALMNMKLALIRVLQNF 463


>DQ924960-1|ABI96208.1|  503|Homo sapiens cytochrome P450 family 3
           subfamily A polypeptide 4 protein.
          Length = 503

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALMNMKLALIRVLQNF 463


>DQ005611-1|AAY16980.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 4 protein.
          Length = 503

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALMNMKLALIRVLQNF 463


>BC101631-1|AAI01632.1|  503|Homo sapiens cytochrome P450, subfamily
           IIIA, polypeptide 4 protein.
          Length = 503

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALMNMKLALIRVLQNF 463


>BC069418-1|AAH69418.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 4 protein.
          Length = 503

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALMNMKLALIRVLQNF 463


>AJ563377-1|CAD91345.1|  353|Homo sapiens cytochrome P450 protein.
          Length = 353

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 177 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 233

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 234 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 292

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 293 IGMRFALMNMKLALIRVLQNF 313


>AJ563376-2|CAD91645.1|  430|Homo sapiens cytochrome P450 protein.
          Length = 430

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 254 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 310

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 311 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 369

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 370 IGMRFALMNMKLALIRVLQNF 390


>AJ563375-1|CAD91343.1|  503|Homo sapiens cytochrome P450 protein.
          Length = 503

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALMNMKLALIRVLQNF 463


>AF280107-2|AAG32290.1|  503|Homo sapiens cytochrome P450
           polypeptide 4 protein.
          Length = 503

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALMNMKLALIRVLQNF 463


>AF209389-1|AAF21034.1|  503|Homo sapiens cytochrome P450 IIIA4
           protein.
          Length = 503

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALMNMKLALIRVLQNF 463


>AF182273-1|AAF13598.1|  503|Homo sapiens cytochrome P450-3A4
           protein.
          Length = 503

 Score = 72.9 bits (171), Expect = 1e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALMNMKLALIRVLQNF 463


>BC100981-1|AAI00982.1|  393|Homo sapiens CYP3A43 protein protein.
          Length = 393

 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +  
Sbjct: 217 VQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-- 273

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  +++  Y LH  P  + + +       S +N    D + R   F  GPR+C
Sbjct: 274 NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSID-LYRYIPFGAGPRNC 332

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A+  +K+ +    + F
Sbjct: 333 IGMRFALTNIKLAVIRALQNF 353


>AY390425-1|AAQ92353.1|  503|Homo sapiens cytochrome P450 CYP3A43.1
           protein.
          Length = 503

 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  +++  Y LH  P  + + +       S +N    D + R   F  GPR+C
Sbjct: 384 NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSID-LYRYIPFGAGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A+  +K+ +    + F
Sbjct: 443 IGMRFALTNIKLAVIRALQNF 463


>AF337813-1|AAK38841.1|  503|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 503

 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  +++  Y LH  P  + + +       S +N    D + R   F  GPR+C
Sbjct: 384 NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSID-LYRYIPFGAGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A+  +K+ +    + F
Sbjct: 443 IGMRFALTNIKLAVIRALQNF 463


>AF319634-1|AAK00325.1|  503|Homo sapiens cytochrome P450 CYP3A43
           protein.
          Length = 503

 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  +++  Y LH  P  + + +       S +N    D + R   F  GPR+C
Sbjct: 384 NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSID-LYRYIPFGAGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A+  +K+ +    + F
Sbjct: 443 IGMRFALTNIKLAVIRALQNF 463


>AF280108-1|AAG33009.1|  503|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 503

 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  +++  Y LH  P  + + +       S +N    D + R   F  GPR+C
Sbjct: 384 NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSID-LYRYIPFGAGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A+  +K+ +    + F
Sbjct: 443 IGMRFALTNIKLAVIRALQNF 463


>AC011904-4|AAS07395.1|  503|Homo sapiens unknown protein.
          Length = 503

 Score = 72.5 bits (170), Expect = 1e-12
 Identities = 42/141 (29%), Positives = 75/141 (53%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  +++  Y LH  P  + + +       S +N    D + R   F  GPR+C
Sbjct: 384 NGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSID-LYRYIPFGAGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A+  +K+ +    + F
Sbjct: 443 IGMRFALTNIKLAVIRALQNF 463


>X12387-1|CAA30944.1|  503|Homo sapiens protein ( Human mRNA for
           cytochrome P-450 (cyp3 locus). ).
          Length = 503

 Score = 72.1 bits (169), Expect = 2e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALMNMKLALIRVLQNF 463


>M14096-1|AAA35744.1|  503|Homo sapiens protein ( Human cytochrome
           P-450 nifedipine oxidase mRNA, complet cds. ).
          Length = 503

 Score = 72.1 bits (169), Expect = 2e-12
 Identities = 43/141 (30%), Positives = 74/141 (52%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSC 611
           NG  IP G  ++I +Y LHR P  Y  +    L   F      +I   +   F  GPR+C
Sbjct: 384 NGMFIPKGWVVMIPSYALHRDPK-YWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALMNMKLALIRVLQNF 463


>M13785-1|AAA35742.1|  504|Homo sapiens protein ( Human liver
           glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
           complete cds. ).
          Length = 504

 Score = 72.1 bits (169), Expect = 2e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 328 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 384

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 385 NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 443

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 444 IGMRFALMNMKLALIRVLQNF 464


>J04449-1|AAA35747.1|  502|Homo sapiens cytochrome P450 nifedipine
           oxidase protein.
          Length = 502

 Score = 72.1 bits (169), Expect = 2e-12
 Identities = 43/141 (30%), Positives = 74/141 (52%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 326 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 382

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSC 611
           NG  IP G  ++I +Y LHR P  Y  +    L   F      +I   +   F  GPR+C
Sbjct: 383 NGMFIPKGWVVMIPSYALHRDPK-YWTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNC 441

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 442 IGMRFALMNMKLALIRVLQNF 462


>D00003-1|BAA00001.1|  504|Homo sapiens cytochrome P-450 protein.
          Length = 504

 Score = 72.1 bits (169), Expect = 2e-12
 Identities = 43/141 (30%), Positives = 77/141 (54%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   P T+   L+M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 328 VQQKLQEEIDAVLPNK-APPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEI-- 384

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LHR P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 385 NGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 443

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 444 IGMRFALMNMKLALIRVLQNF 464


>J04813-1|AAA02993.1|  502|Homo sapiens cytochrome P450 PCN3
           protein.
          Length = 502

 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 39/140 (27%), Positives = 72/140 (51%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ +E+D +  +   P T+   ++M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           NG  IP G+ +VI TY LH  P  +            +     D  + +  F  GPR+C+
Sbjct: 384 NGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYT-PFGTGPRNCI 442

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G ++A++ +K+ L    + F
Sbjct: 443 GMRFALMNMKLALIRVLQNF 462


>BC033862-1|AAH33862.1|  502|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 5 protein.
          Length = 502

 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 39/140 (27%), Positives = 72/140 (51%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ +E+D +  +   P T+   ++M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           NG  IP G+ +VI TY LH  P  +            +     D  + +  F  GPR+C+
Sbjct: 384 NGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYT-PFGTGPRNCI 442

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G ++A++ +K+ L    + F
Sbjct: 443 GMRFALMNMKLALIRVLQNF 462


>AC005020-1|AAS02016.1|  502|Homo sapiens unknown protein.
          Length = 502

 Score = 68.9 bits (161), Expect = 2e-11
 Identities = 39/140 (27%), Positives = 72/140 (51%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ +E+D +  +   P T+   ++M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           NG  IP G+ +VI TY LH  P  +            +     D  + +  F  GPR+C+
Sbjct: 384 NGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYT-PFGTGPRNCI 442

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G ++A++ +K+ L    + F
Sbjct: 443 GMRFALMNMKLALIRVLQNF 462


>X71480-1|CAA50586.1|  141|Homo sapiens cytochrome P450 protein.
          Length = 141

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 31/84 (36%), Positives = 52/84 (61%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I+R+++  +T P +
Sbjct: 28  QERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGISRELSTPVTFP-D 85

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY 509
           G+ +P G T++++ Y LH  P V+
Sbjct: 86  GRSLPKGITVMLSIYGLHHNPKVW 109



 Score = 36.7 bits (81), Expect = 0.079
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +2

Query: 509 PNPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           PNP  FDP  F P   + +H +AF+PFS G++
Sbjct: 110 PNPEVFDPSRFAP--GSAQHSHAFLPFSGGSR 139



 Score = 30.7 bits (66), Expect = 5.2
 Identities = 12/30 (40%), Positives = 19/30 (63%)
 Frame = +1

Query: 178 TIMFEGHXXTAAGSSFFLSMMGIHQEYKTK 267
           T MFEGH  TA+G S+ L  +  H +++ +
Sbjct: 1   TFMFEGHDTTASGISWILYALATHPKHQER 30


>D00408-1|BAA00310.1|  503|Homo sapiens cytochrome P-450 HFLa
           protein.
          Length = 503

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 41/141 (29%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q KV +E+D +  +   P T+   L+++YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKVQKEIDTVLPNK-APPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LH  P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALVNMKLALVRVLQNF 463


>BC067436-1|AAH67436.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 7 protein.
          Length = 503

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 41/141 (29%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q KV +E+D +  +   P T+   L+++YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKVQKEIDTVLPNK-APPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LH  P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALVNMKLALVRVLQNF 463


>AF315325-1|AAG48618.1|  535|Homo sapiens cytochrome P450 variant
           3A7 protein.
          Length = 535

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 41/141 (29%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q KV +E+D +  +   P T+   L+++YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKVQKEIDTVLPNK-APPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LH  P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALVNMKLALVRVLQNF 463


>AF280107-3|AAG32289.1|  503|Homo sapiens cytochrome P450
           polypeptide 7 protein.
          Length = 503

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 41/141 (29%), Positives = 76/141 (53%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q KV +E+D +  +   P T+   L+++YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKVQKEIDTVLPNK-APPTYDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY-QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
           NG  IP G  ++I +Y LH  P  + + +  L    S +N    D  + +  F  GPR+C
Sbjct: 384 NGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYT-PFGSGPRNC 442

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G ++A++ +K+ L    + F
Sbjct: 443 IGMRFALVNMKLALVRVLQNF 463


>AK223008-1|BAD96728.1|  502|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 5 variant protein.
          Length = 502

 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 39/140 (27%), Positives = 72/140 (51%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ +E+D +  +   P T+   ++M+YL+  + ETLRL+P    + R   +++ +  
Sbjct: 327 VQQKLQKEIDAVLPNK-APPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCMKDVEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           NG  IP G+ +VI TY LH  P  +            +     D  + +  F  GPR+C+
Sbjct: 384 NGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDSIDPYIYTP-FGTGPRNCI 442

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G ++A++ +K+ L    + F
Sbjct: 443 GMRFALMNMKLALIRVLQNF 462


>AY358631-1|AAQ88994.1|  505|Homo sapiens EPSW3060 protein.
          Length = 505

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 42/143 (29%), Positives = 75/143 (52%), Gaps = 4/143 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  +E+ ++ GD    +T++   +M Y   C+ E LRLY PV  I+R +++ IT P +
Sbjct: 337 QQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFP-D 394

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLT-TSFRNVPPTDIIMRSCLFQLGPR 605
           G+ +PAG T+ I  + LH  P  +   Q+   L  +  +   + P   I     F  G R
Sbjct: 395 GRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIP----FSAGLR 450

Query: 606 SCVGRKYAMLKLKVILFYNFEKF 674
           +C+G+ +A+++ KV +     +F
Sbjct: 451 NCIGQHFAIIECKVAVALTLLRF 473


>AY262056-1|AAO89257.1|  505|Homo sapiens cytochrome P450 protein.
          Length = 505

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 42/143 (29%), Positives = 75/143 (52%), Gaps = 4/143 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  +E+ ++ GD    +T++   +M Y   C+ E LRLY PV  I+R +++ IT P +
Sbjct: 337 QQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFP-D 394

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLT-TSFRNVPPTDIIMRSCLFQLGPR 605
           G+ +PAG T+ I  + LH  P  +   Q+   L  +  +   + P   I     F  G R
Sbjct: 395 GRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIP----FSAGLR 450

Query: 606 SCVGRKYAMLKLKVILFYNFEKF 674
           +C+G+ +A+++ KV +     +F
Sbjct: 451 NCIGQHFAIIECKVAVALTLLRF 473


>AL450996-2|CAH71036.1|  505|Homo sapiens cytochrome P450, family 4,
           subfamily Z, polypeptide 1 protein.
          Length = 505

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 42/143 (29%), Positives = 75/143 (52%), Gaps = 4/143 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  +E+ ++ GD    +T++   +M Y   C+ E LRLY PV  I+R +++ IT P +
Sbjct: 337 QQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFP-D 394

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLT-TSFRNVPPTDIIMRSCLFQLGPR 605
           G+ +PAG T+ I  + LH  P  +   Q+   L  +  +   + P   I     F  G R
Sbjct: 395 GRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIP----FSAGLR 450

Query: 606 SCVGRKYAMLKLKVILFYNFEKF 674
           +C+G+ +A+++ KV +     +F
Sbjct: 451 NCIGQHFAIIECKVAVALTLLRF 473


>AL135960-6|CAI19734.1|  505|Homo sapiens cytochrome P450, family 4,
           subfamily Z, polypeptide 1 protein.
          Length = 505

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 42/143 (29%), Positives = 75/143 (52%), Gaps = 4/143 (2%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q +  +E+ ++ GD    +T++   +M Y   C+ E LRLY PV  I+R +++ IT P +
Sbjct: 337 QQRCRDEIRELLGDGSS-ITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFP-D 394

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY---QIQTNLTLT-TSFRNVPPTDIIMRSCLFQLGPR 605
           G+ +PAG T+ I  + LH  P  +   Q+   L  +  +   + P   I     F  G R
Sbjct: 395 GRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIP----FSAGLR 450

Query: 606 SCVGRKYAMLKLKVILFYNFEKF 674
           +C+G+ +A+++ KV +     +F
Sbjct: 451 NCIGQHFAIIECKVAVALTLLRF 473


>BC041158-1|AAH41158.1|  455|Homo sapiens CYP4A11 protein protein.
          Length = 455

 Score = 66.5 bits (155), Expect = 9e-11
 Identities = 30/84 (35%), Positives = 50/84 (59%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY 509
           G+ +P G  ++++ Y LH  P V+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW 425



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346



 Score = 35.5 bits (78), Expect = 0.18
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +2

Query: 509 PNPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           PNP  FDP  F P   + +H +AF+PFS G++
Sbjct: 426 PNPEVFDPFRFAP--GSAQHSHAFLPFSGGSR 455


>AL731892-4|CAH72779.1|  455|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 11 protein.
          Length = 455

 Score = 66.5 bits (155), Expect = 9e-11
 Identities = 30/84 (35%), Positives = 50/84 (59%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY 509
           G+ +P G  ++++ Y LH  P V+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW 425



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346



 Score = 35.5 bits (78), Expect = 0.18
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +2

Query: 509 PNPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           PNP  FDP  F P   + +H +AF+PFS G++
Sbjct: 426 PNPEVFDPFRFAP--GSAQHSHAFLPFSGGSR 455


>BC142607-1|AAI42608.1|  455|Homo sapiens CYP4A22 protein protein.
          Length = 455

 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 30/84 (35%), Positives = 50/84 (59%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY 509
           G+ +P G  ++++ Y LH  P V+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW 425



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346



 Score = 36.7 bits (81), Expect = 0.079
 Identities = 15/32 (46%), Positives = 21/32 (65%)
 Frame = +2

Query: 509 PNPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           PNP  FDP  F P   + +H +AF+PFS G++
Sbjct: 426 PNPEVFDPSRFAP--GSAQHSHAFLPFSGGSR 455


>AL135960-11|CAI19738.1|  455|Homo sapiens cytochrome P450, family
           4, subfamily A, polypeptide 22 protein.
          Length = 455

 Score = 65.7 bits (153), Expect = 1e-10
 Identities = 30/84 (35%), Positives = 50/84 (59%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSN 437
           Q++  EE+  + GD    +T+    +M Y   C+ E LRLYPPVP I R+++  +T P +
Sbjct: 344 QERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-D 401

Query: 438 GKKIPAGTTLVIATYKLHRRPDVY 509
           G+ +P G  ++++ Y LH  P V+
Sbjct: 402 GRSLPKGIMVLLSIYGLHHNPKVW 425



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 25/62 (40%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           +K+ L FLD LLL   ++G  +SD++++ +VDT MFEGH  TA+G S+ L  +  H +++
Sbjct: 285 RKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQ 344

Query: 262 TK 267
            +
Sbjct: 345 ER 346



 Score = 32.7 bits (71), Expect = 1.3
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = +2

Query: 509 PNPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           PN   FDP  F P   + +H +AF+PFS G++
Sbjct: 426 PNLEVFDPSRFAP--GSAQHSHAFLPFSGGSR 455


>BC022539-1|AAH22539.1|  500|Homo sapiens cytochrome P450, family
           46, subfamily A, polypeptide 1 protein.
          Length = 500

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 40/126 (31%), Positives = 68/126 (53%)
 Frame = +3

Query: 276 ELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 455
           E+D++ G S R + F+D   ++YL + L E+LRLYPP     R + +E  +  +G ++P 
Sbjct: 331 EVDEVIG-SKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI--DGVRVPG 387

Query: 456 GTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAML 635
            T L+ +TY + R  D Y  +  LT                   F LG RSC+G+++A +
Sbjct: 388 NTPLLFSTYVMGRM-DTY-FEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQM 445

Query: 636 KLKVIL 653
           ++KV++
Sbjct: 446 EVKVVM 451


>AF094480-1|AAD41244.1|  500|Homo sapiens cholesterol 24-hydroxylase
           protein.
          Length = 500

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 40/126 (31%), Positives = 68/126 (53%)
 Frame = +3

Query: 276 ELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 455
           E+D++ G S R + F+D   ++YL + L E+LRLYPP     R + +E  +  +G ++P 
Sbjct: 331 EVDEVIG-SKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLI--DGVRVPG 387

Query: 456 GTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAML 635
            T L+ +TY + R  D Y  +  LT                   F LG RSC+G+++A +
Sbjct: 388 NTPLLFSTYVMGRM-DTY-FEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQM 445

Query: 636 KLKVIL 653
           ++KV++
Sbjct: 446 EVKVVM 451


>AJ563378-3|CAD91347.1|  173|Homo sapiens hypothetical protein
           protein.
          Length = 173

 Score = 63.3 bits (147), Expect = 8e-10
 Identities = 35/122 (28%), Positives = 62/122 (50%)
 Frame = +3

Query: 309 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 488
           P T+   ++M+YL+  + ETLRL+P    + R   +++ +  NG  IP G+ +VI TY L
Sbjct: 15  PPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYAL 72

Query: 489 HRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFYNFE 668
           H  P  +            +     D  + +  F  GPR+C+G ++A++ +K+ L    +
Sbjct: 73  HHDPKYWTEPEEFRPERFSKKKDSIDPYIYT-PFGTGPRNCIGMRFALMNMKLALIRVLQ 131

Query: 669 KF 674
            F
Sbjct: 132 NF 133


>AJ563378-2|CAD91647.1|  160|Homo sapiens cytochrome P450 protein.
          Length = 160

 Score = 63.3 bits (147), Expect = 8e-10
 Identities = 35/122 (28%), Positives = 62/122 (50%)
 Frame = +3

Query: 309 PVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKL 488
           P T+   ++M+YL+  + ETLRL+P    + R   +++ +  NG  IP G+ +VI TY L
Sbjct: 2   PPTYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEI--NGVFIPKGSMVVIPTYAL 59

Query: 489 HRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFYNFE 668
           H  P  +            +     D  + +  F  GPR+C+G ++A++ +K+ L    +
Sbjct: 60  HHDPKYWTEPEEFRPERFSKKKDSIDPYIYT-PFGTGPRNCIGMRFALMNMKLALIRVLQ 118

Query: 669 KF 674
            F
Sbjct: 119 NF 120


>AF233624-1|AAF99278.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 62.5 bits (145), Expect = 1e-09
 Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +    N                     F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPENFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501



 Score = 30.7 bits (66), Expect = 5.2
 Identities = 11/36 (30%), Positives = 18/36 (50%)
 Frame = +2

Query: 497 P*RLPNPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           P   P+P  F+P+ F  E       + ++PF AG +
Sbjct: 443 PEHWPSPENFNPERFTAEARQQHRPFTYLPFGAGPR 478


>M80647-1|AAA60618.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>BC041157-1|AAH41157.1|  534|Homo sapiens thromboxane A synthase 1
           (platelet, cytochrome P450, family 5, subfamily A)
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>BC014117-1|AAH14117.1|  466|Homo sapiens TBXAS1 protein protein.
          Length = 466

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 297 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 354

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 355 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 413

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 414 GVRLGLLEVKLTLLHVLHKF 433


>AK223466-1|BAD97186.1|  534|Homo sapiens thromboxane A synthase 1
           (platelet, cytochrome P450, family 5, subfamily A) iso
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>AF233625-1|AAF99279.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHQPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>AF233623-1|AAF99277.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPKTFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>AF233621-1|AAF99275.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>AF233620-1|AAF99274.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>AF233619-1|AAF99273.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>AF233618-1|AAF99272.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>AF233617-1|AAF99271.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>AF233616-1|AAF99270.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>AF233615-1|AAF99269.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>L13286-1|AAA62379.1|  513|Homo sapiens 1,25-dihydroxyvitamin D3
           24-hydroxylase protein.
          Length = 513

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 37/141 (26%), Positives = 68/141 (48%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 431
           ++Q K+++E+  +  ++ RP   +D   M YL+ CL E++RL P VP   R +++   L 
Sbjct: 346 QVQQKLLKEIQSVLPENQRPRE-EDLRNMPYLKACLKESMRLTPGVPFTTRTLDKATVLG 404

Query: 432 SNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
                +P GT L++ T  L    D ++  +        +     +       F +G R C
Sbjct: 405 EYA--LPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAH-LPFGVGKRMC 461

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +GR+ A L+L + L +   K+
Sbjct: 462 IGRRLAELQLHLALCWIVRKY 482


>D34625-1|BAA07011.1|  533|Homo sapiens thromboxane synthase
           protein.
          Length = 533

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 364 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVL- 421

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 422 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 480

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G    +L++K+ L +   KF
Sbjct: 481 GVHLGLLEVKLTLLHVLHKF 500



 Score = 30.3 bits (65), Expect = 6.9
 Identities = 11/36 (30%), Positives = 18/36 (50%)
 Frame = +2

Query: 497 P*RLPNPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           P   P+P  F+P+ F  E       + ++PF AG +
Sbjct: 442 PEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPR 477


>AF233622-1|AAF99276.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score = 58.8 bits (136), Expect = 2e-08
 Identities = 39/140 (27%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  ++  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAEDCEVL- 422

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G++IPAG  L +A   LH  P+ +                          F  GPRSC+
Sbjct: 423 -GQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCL 481

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G +  +L++K+ L +   KF
Sbjct: 482 GVRLGLLEVKLTLLHVLHKF 501


>BC142690-1|AAI42691.1|  357|Homo sapiens CYP4A22 protein protein.
          Length = 357

 Score = 58.4 bits (135), Expect = 2e-08
 Identities = 24/59 (40%), Positives = 38/59 (64%)
 Frame = +3

Query: 333 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVY 509
           +M Y   C+ E LRLYPPVP I R+++  +T P +G+ +P G  ++++ Y LH  P V+
Sbjct: 270 QMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP-DGRSLPKGIMVLLSIYGLHHNPKVW 327



 Score = 32.7 bits (71), Expect = 1.3
 Identities = 14/32 (43%), Positives = 20/32 (62%)
 Frame = +2

Query: 509 PNPNKFDPDNFLPERSANRHYYAFVPFSAGTK 604
           PN   FDP  F P   + +H +AF+PFS G++
Sbjct: 328 PNLEVFDPSRFAP--GSAQHSHAFLPFSGGSR 357


>Y07508-1|CAA68807.1|  503|Homo sapiens protein ( Human mRNA for
           aromatase P-450. ).
          Length = 503

 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 69/140 (49%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +++ +I+E+  + G+ D  +   D  ++K +E  + E++R  P V ++ R+  ++  +  
Sbjct: 328 VEEAIIKEIQTVIGERD--IKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G  +  GT +++   ++HR  + +      TL    +NVP          F  GPR C 
Sbjct: 384 DGYPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAKNVPYRYFQP----FGFGPRGCA 438

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+  AM+ +K IL     +F
Sbjct: 439 GKYIAMVMMKAILVTLLRRF 458


>X13589-1|CAA31929.1|  503|Homo sapiens protein ( Human mRNA for
           aromatase (estrogen synthetase). ).
          Length = 503

 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 69/140 (49%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +++ +I+E+  + G+ D  +   D  ++K +E  + E++R  P V ++ R+  ++  +  
Sbjct: 328 VEEAIIKEIQTVIGERD--IKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G  +  GT +++   ++HR  + +      TL    +NVP          F  GPR C 
Sbjct: 384 DGYPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAKNVPYRYFQP----FGFGPRGCA 438

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+  AM+ +K IL     +F
Sbjct: 439 GKYIAMVMMKAILVTLLRRF 458


>M30804-1|AAA35728.1|  503|Homo sapiens protein ( Human aromatase
           cytochrome P-450 gene, exon 10. ).
          Length = 503

 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 69/140 (49%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +++ +I+E+  + G+ D  +   D  ++K +E  + E++R  P V ++ R+  ++  +  
Sbjct: 328 VEEAIIKEIQTVIGERD--IKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G  +  GT +++   ++HR  + +      TL    +NVP          F  GPR C 
Sbjct: 384 DGYPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAKNVPYRYFQP----FGFGPRGCA 438

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+  AM+ +K IL     +F
Sbjct: 439 GKYIAMVMMKAILVTLLRRF 458


>M28420-1|AAA52141.1|  419|Homo sapiens cytochrome P-450 aromatase
           protein.
          Length = 419

 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 69/140 (49%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +++ +I+E+  + G+ D  +   D  ++K +E  + E++R  P V ++ R+  ++  +  
Sbjct: 244 VEEAIIKEIQTVIGERD--IKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI-- 299

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G  +  GT +++   ++HR  + +      TL    +NVP          F  GPR C 
Sbjct: 300 DGYPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAKNVPYRYFQP----FGFGPRGCA 354

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+  AM+ +K IL     +F
Sbjct: 355 GKYIAMVMMKAILVTLLRRF 374


>M22246-1|AAA35557.1|  503|Homo sapiens protein ( Human aromatase
           mRNA, complete cds. ).
          Length = 503

 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 69/140 (49%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +++ +I+E+  + G+ D  +   D  ++K +E  + E++R  P V ++ R+  ++  +  
Sbjct: 328 VEEAIIKEIQTVIGERD--IKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G  +  GT +++   ++HR  + +      TL    +NVP          F  GPR C 
Sbjct: 384 DGYPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAKNVPYRYFQP----FGFGPRGCA 438

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+  AM+ +K IL     +F
Sbjct: 439 GKYIAMVMMKAILVTLLRRF 458


>M18856-1|AAA35556.1|  419|Homo sapiens protein ( Human aromatase
           (Aro1) mRNA, complete cds. ).
          Length = 419

 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 69/140 (49%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +++ +I+E+  + G+ D  +   D  ++K +E  + E++R  P V ++ R+  ++  +  
Sbjct: 244 VEEAIIKEIQTVIGERD--IKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI-- 299

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G  +  GT +++   ++HR  + +      TL    +NVP          F  GPR C 
Sbjct: 300 DGYPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAKNVPYRYFQP----FGFGPRGCA 354

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+  AM+ +K IL     +F
Sbjct: 355 GKYIAMVMMKAILVTLLRRF 374


>J04127-1|AAA52132.1|  503|Homo sapiens CYP19 protein.
          Length = 503

 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 69/140 (49%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +++ +I+E+  + G+ D  +   D  ++K +E  + E++R  P V ++ R+  ++  +  
Sbjct: 328 VEEAIIKEIQTVIGERD--IKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G  +  GT +++   ++HR  + +      TL    +NVP          F  GPR C 
Sbjct: 384 DGYPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAKNVPYRYFQP----FGFGPRGCA 438

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+  AM+ +K IL     +F
Sbjct: 439 GKYIAMVMMKAILVTLLRRF 458


>DQ118405-1|AAZ23558.1|  503|Homo sapiens cytochrome P450 subfamily
           19 subfamily A polypeptide 1 protein.
          Length = 503

 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 69/140 (49%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +++ +I+E+  + G+ D  +   D  ++K +E  + E++R  P V ++ R+  ++  +  
Sbjct: 328 VEEAIIKEIQTVIGERD--IKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G  +  GT +++   ++HR  + +      TL    +NVP          F  GPR C 
Sbjct: 384 DGYPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAKNVPYRYFQP----FGFGPRGCA 438

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+  AM+ +K IL     +F
Sbjct: 439 GKYIAMVMMKAILVTLLRRF 458


>BC107785-1|AAI07786.1|  503|Homo sapiens cytochrome P450, family
           19, subfamily A, polypeptide 1 protein.
          Length = 503

 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 69/140 (49%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +++ +I+E+  + G+ D  +   D  ++K +E  + E++R  P V ++ R+  ++  +  
Sbjct: 328 VEEAIIKEIQTVIGERD--IKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G  +  GT +++   ++HR  + +      TL    +NVP          F  GPR C 
Sbjct: 384 DGYPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAKNVPYRYFQP----FGFGPRGCA 438

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+  AM+ +K IL     +F
Sbjct: 439 GKYIAMVMMKAILVTLLRRF 458


>BC035959-1|AAH35959.1|  503|Homo sapiens cytochrome P450, family
           19, subfamily A, polypeptide 1 protein.
          Length = 503

 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 69/140 (49%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +++ +I+E+  + G+ D  +   D  ++K +E  + E++R  P V ++ R+  ++  +  
Sbjct: 328 VEEAIIKEIQTVIGERD--IKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G  +  GT +++   ++HR  + +      TL    +NVP          F  GPR C 
Sbjct: 384 DGYPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAKNVPYRYFQP----FGFGPRGCA 438

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+  AM+ +K IL     +F
Sbjct: 439 GKYIAMVMMKAILVTLLRRF 458


>AY957953-1|AAX44046.1|  503|Homo sapiens cytochrome P450, family
           19, subfamily A, polypeptide 1 protein.
          Length = 503

 Score = 57.6 bits (133), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 69/140 (49%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +++ +I+E+  + G+ D  +   D  ++K +E  + E++R  P V ++ R+  ++  +  
Sbjct: 328 VEEAIIKEIQTVIGERD--IKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
           +G  +  GT +++   ++HR  + +      TL    +NVP          F  GPR C 
Sbjct: 384 DGYPVKKGTNIILNIGRMHRL-EFFPKPNEFTLENFAKNVPYRYFQP----FGFGPRGCA 438

Query: 615 GRKYAMLKLKVILFYNFEKF 674
           G+  AM+ +K IL     +F
Sbjct: 439 GKYIAMVMMKAILVTLLRRF 458


>BC100982-1|AAI00983.1|  280|Homo sapiens CYP3A43 protein protein.
          Length = 280

 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/82 (35%), Positives = 48/82 (58%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +  
Sbjct: 187 VQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-- 243

Query: 435 NGKKIPAGTTLVIATYKLHRRP 500
           NG  IP G  +++  Y LH  P
Sbjct: 244 NGVFIPKGLAVMVPIYALHHDP 265


>AF280110-1|AAG33011.1|  420|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 420

 Score = 57.2 bits (132), Expect = 5e-08
 Identities = 29/82 (35%), Positives = 48/82 (58%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K+ EE+D +  +   PVT+   ++M+YL+  + ETLRL+P V  + R   ++I +  
Sbjct: 327 VQQKLQEEIDAVLPNK-APVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI-- 383

Query: 435 NGKKIPAGTTLVIATYKLHRRP 500
           NG  IP G  +++  Y LH  P
Sbjct: 384 NGVFIPKGLAVMVPIYALHHDP 405


>S67623-1|AAB29308.1|  257|Homo sapiens 25-hydroxyvitamin D
           24-hydroxylase cytochrome P450 subunit protein.
          Length = 257

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 36/141 (25%), Positives = 67/141 (47%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 431
           ++Q K+++E+  +  ++  P   +D   M YL+ CL E++RL P VP   R +++   L 
Sbjct: 90  QVQQKLLKEIQSVLPENQVPRA-EDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLG 148

Query: 432 SNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
                +P GT L++ T  L    D ++  +        +     +       F +G R C
Sbjct: 149 EYA--LPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAH-LPFGVGKRMC 205

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +GR+ A L+L + L +   K+
Sbjct: 206 IGRRLAELQLHLALCWIVRKY 226


>D12621-1|BAA02145.1|  389|Homo sapiens cytochrome P-450LTBV
           protein.
          Length = 389

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 27/62 (43%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
 Frame = +1

Query: 85  QKKRLAFLD-LLLESSQSGVAISDEEIKEQVDTIMFEGHXXTAAGSSFFLSMMGIHQEYK 261
           + K L F+D LLL   + G  +SDE+I+ + DT MFEGH  TA+G S+ L  +  H EY+
Sbjct: 292 KSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQ 351

Query: 262 TK 267
            +
Sbjct: 352 ER 353


>AY858838-1|AAW50795.1|  372|Homo sapiens vitamin D 24-hydroxylase
           splice variant protein.
          Length = 372

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 36/141 (25%), Positives = 67/141 (47%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 431
           ++Q K+++E+  +  ++  P   +D   M YL+ CL E++RL P VP   R +++   L 
Sbjct: 205 QVQQKLLKEIQSVLPENQVPRA-EDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLG 263

Query: 432 SNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
                +P GT L++ T  L    D ++  +        +     +       F +G R C
Sbjct: 264 EYA--LPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAH-LPFGVGKRMC 320

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +GR+ A L+L + L +   K+
Sbjct: 321 IGRRLAELQLHLALCWIVRKY 341


>AL138805-2|CAB91829.1|  514|Homo sapiens cytochrome P450, family
           24, subfamily A, polypeptide 1 protein.
          Length = 514

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 36/141 (25%), Positives = 67/141 (47%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 431
           ++Q K+++E+  +  ++  P   +D   M YL+ CL E++RL P VP   R +++   L 
Sbjct: 347 QVQQKLLKEIQSVLPENQVPRA-EDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLG 405

Query: 432 SNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
                +P GT L++ T  L    D ++  +        +     +       F +G R C
Sbjct: 406 EYA--LPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAH-LPFGVGKRMC 462

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +GR+ A L+L + L +   K+
Sbjct: 463 IGRRLAELQLHLALCWIVRKY 483


>AL138805-1|CAM27342.1|  372|Homo sapiens cytochrome P450, family
           24, subfamily A, polypeptide 1 protein.
          Length = 372

 Score = 56.4 bits (130), Expect = 9e-08
 Identities = 36/141 (25%), Positives = 67/141 (47%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLP 431
           ++Q K+++E+  +  ++  P   +D   M YL+ CL E++RL P VP   R +++   L 
Sbjct: 205 QVQQKLLKEIQSVLPENQVPRA-EDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLG 263

Query: 432 SNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSC 611
                +P GT L++ T  L    D ++  +        +     +       F +G R C
Sbjct: 264 EYA--LPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKEKINPFAH-LPFGVGKRMC 320

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +GR+ A L+L + L +   K+
Sbjct: 321 IGRRLAELQLHLALCWIVRKY 341


>X59812-1|CAA42481.1|  530|Homo sapiens Vitamin D3 25-hydroxylase
           protein.
          Length = 530

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 4/144 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           IQ+ + EE+  +      P   +D   M  L+  L ETLRLYP VP  +R + +EI +  
Sbjct: 356 IQEALHEEVVGVVPAGQVP-QHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV-- 412

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY----QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           +G   P  T  V   Y + R P  +      Q +  L  S    P       S  F  G 
Sbjct: 413 DGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGV 472

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+GR+ A L+++++L    +K+
Sbjct: 473 RACLGRRIAELEMQLLLARLIQKY 496


>M63871-1|AAA59984.1|  508|Homo sapiens CYP17 protein.
          Length = 508

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 4/148 (2%)
 Frame = +3

Query: 243 YSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVP-IIARQVNQE 419
           ++ +++ K+ EE+DQ  G S  P T  D   +  LE  + E LRL P  P +I  + N +
Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL---F 590
            ++      +  GT ++I  + LH     +  Q +  +   F N   T +I  S     F
Sbjct: 379 SSIGEFA--VDKGTEVIINLWALHHNEKEWH-QPDQFMPERFLNPAGTQLISPSVSYLPF 435

Query: 591 QLGPRSCVGRKYAMLKLKVILFYNFEKF 674
             GPRSC+G   A  +L +I+ +  ++F
Sbjct: 436 GAGPRSCIGEILARQELFLIMAWLLQRF 463


>M62401-1|AAA52142.1|  531|Homo sapiens sterol 27-hydroxylase
           protein.
          Length = 531

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 4/144 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           IQ+ + EE+  +      P   +D   M  L+  L ETLRLYP VP  +R + +EI +  
Sbjct: 357 IQEALHEEVVGVVPAGQVP-QHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV-- 413

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY----QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           +G   P  T  V   Y + R P  +      Q +  L  S    P       S  F  G 
Sbjct: 414 DGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGV 473

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+GR+ A L+++++L    +K+
Sbjct: 474 RACLGRRIAELEMQLLLARLIQKY 497


>M31153-1|AAA52140.1|  508|Homo sapiens CYP17 protein.
          Length = 508

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 4/148 (2%)
 Frame = +3

Query: 243 YSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVP-IIARQVNQE 419
           ++ +++ K+ EE+DQ  G S  P T  D   +  LE  + E LRL P  P +I  + N +
Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL---F 590
            ++      +  GT ++I  + LH     +  Q +  +   F N   T +I  S     F
Sbjct: 379 SSIGEFA--VDKGTEVIINLWALHHNEKEWH-QPDQFMPERFLNPAGTQLISPSVSYLPF 435

Query: 591 QLGPRSCVGRKYAMLKLKVILFYNFEKF 674
             GPRSC+G   A  +L +I+ +  ++F
Sbjct: 436 GAGPRSCIGEILARQELFLIMAWLLQRF 463


>M19489-1|AAA36405.1|  508|Homo sapiens CYP17 protein.
          Length = 508

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 4/148 (2%)
 Frame = +3

Query: 243 YSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVP-IIARQVNQE 419
           ++ +++ K+ EE+DQ  G S  P T  D   +  LE  + E LRL P  P +I  + N +
Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL---F 590
            ++      +  GT ++I  + LH     +  Q +  +   F N   T +I  S     F
Sbjct: 379 SSIGEFA--VDKGTEVIINLWALHHNEKEWH-QPDQFMPERFLNPAGTQLISPSVSYLPF 435

Query: 591 QLGPRSCVGRKYAMLKLKVILFYNFEKF 674
             GPRSC+G   A  +L +I+ +  ++F
Sbjct: 436 GAGPRSCIGEILARQELFLIMAWLLQRF 463


>M14564-1|AAA52151.1|  508|Homo sapiens CYP17 protein.
          Length = 508

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 4/148 (2%)
 Frame = +3

Query: 243 YSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVP-IIARQVNQE 419
           ++ +++ K+ EE+DQ  G S  P T  D   +  LE  + E LRL P  P +I  + N +
Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL---F 590
            ++      +  GT ++I  + LH     +  Q +  +   F N   T +I  S     F
Sbjct: 379 SSIGEFA--VDKGTEVIINLWALHHNEKEWH-QPDQFMPERFLNPAGTQLISPSVSYLPF 435

Query: 591 QLGPRSCVGRKYAMLKLKVILFYNFEKF 674
             GPRSC+G   A  +L +I+ +  ++F
Sbjct: 436 GAGPRSCIGEILARQELFLIMAWLLQRF 463


>DQ530598-1|ABF50972.1|  508|Homo sapiens cytochrome P450, family
           17, subfamily A, polypeptide 1 protein.
          Length = 508

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 4/148 (2%)
 Frame = +3

Query: 243 YSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVP-IIARQVNQE 419
           ++ +++ K+ EE+DQ  G S  P T  D   +  LE  + E LRL P  P +I  + N +
Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL---F 590
            ++      +  GT ++I  + LH     +  Q +  +   F N   T +I  S     F
Sbjct: 379 SSIGEFA--VDKGTEVIINLWALHHNEKEWH-QPDQFMPERFLNPAGTQLISPSVSYLPF 435

Query: 591 QLGPRSCVGRKYAMLKLKVILFYNFEKF 674
             GPRSC+G   A  +L +I+ +  ++F
Sbjct: 436 GAGPRSCIGEILARQELFLIMAWLLQRF 463


>BT020000-1|AAV38803.1|  508|Homo sapiens cytochrome P450, family
           17, subfamily A, polypeptide 1 protein.
          Length = 508

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 4/148 (2%)
 Frame = +3

Query: 243 YSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVP-IIARQVNQE 419
           ++ +++ K+ EE+DQ  G S  P T  D   +  LE  + E LRL P  P +I  + N +
Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL---F 590
            ++      +  GT ++I  + LH     +  Q +  +   F N   T +I  S     F
Sbjct: 379 SSIGEFA--VDKGTEVIINLWALHHNEKEWH-QPDQFMPERFLNPAGTQLISPSVSYLPF 435

Query: 591 QLGPRSCVGRKYAMLKLKVILFYNFEKF 674
             GPRSC+G   A  +L +I+ +  ++F
Sbjct: 436 GAGPRSCIGEILARQELFLIMAWLLQRF 463


>BC063388-1|AAH63388.1|  508|Homo sapiens cytochrome P450, family
           17, subfamily A, polypeptide 1 protein.
          Length = 508

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 4/148 (2%)
 Frame = +3

Query: 243 YSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVP-IIARQVNQE 419
           ++ +++ K+ EE+DQ  G S  P T  D   +  LE  + E LRL P  P +I  + N +
Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL---F 590
            ++      +  GT ++I  + LH     +  Q +  +   F N   T +I  S     F
Sbjct: 379 SSIGEFA--VDKGTEVIINLWALHHNEKEWH-QPDQFMPERFLNPAGTQLISPSVSYLPF 435

Query: 591 QLGPRSCVGRKYAMLKLKVILFYNFEKF 674
             GPRSC+G   A  +L +I+ +  ++F
Sbjct: 436 GAGPRSCIGEILARQELFLIMAWLLQRF 463


>BC062997-1|AAH62997.1|  508|Homo sapiens cytochrome P450, family
           17, subfamily A, polypeptide 1 protein.
          Length = 508

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 4/148 (2%)
 Frame = +3

Query: 243 YSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVP-IIARQVNQE 419
           ++ +++ K+ EE+DQ  G S  P T  D   +  LE  + E LRL P  P +I  + N +
Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL---F 590
            ++      +  GT ++I  + LH     +  Q +  +   F N   T +I  S     F
Sbjct: 379 SSIGEFA--VDKGTEVIINLWALHHNEKEWH-QPDQFMPERFLNPAGTQLISPSVSYLPF 435

Query: 591 QLGPRSCVGRKYAMLKLKVILFYNFEKF 674
             GPRSC+G   A  +L +I+ +  ++F
Sbjct: 436 GAGPRSCIGEILARQELFLIMAWLLQRF 463


>BC051851-1|AAH51851.1|  531|Homo sapiens cytochrome P450, family
           27, subfamily A, polypeptide 1 protein.
          Length = 531

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 4/144 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           IQ+ + EE+  +      P   +D   M  L+  L ETLRLYP VP  +R + +EI +  
Sbjct: 357 IQEALHEEVVGVVPAGQVP-QHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV-- 413

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY----QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           +G   P  T  V   Y + R P  +      Q +  L  S    P       S  F  G 
Sbjct: 414 DGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGV 473

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+GR+ A L+++++L    +K+
Sbjct: 474 RACLGRRIAELEMQLLLARLIQKY 497


>BC040430-1|AAH40430.1|  531|Homo sapiens cytochrome P450, family
           27, subfamily A, polypeptide 1 protein.
          Length = 531

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 4/144 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           IQ+ + EE+  +      P   +D   M  L+  L ETLRLYP VP  +R + +EI +  
Sbjct: 357 IQEALHEEVVGVVPAGQVP-QHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV-- 413

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVY----QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           +G   P  T  V   Y + R P  +      Q +  L  S    P       S  F  G 
Sbjct: 414 DGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGV 473

Query: 603 RSCVGRKYAMLKLKVILFYNFEKF 674
           R+C+GR+ A L+++++L    +K+
Sbjct: 474 RACLGRRIAELEMQLLLARLIQKY 497


>AY178622-1|AAO21126.1|  531|Homo sapiens steroid hydroxylase
           protein.
          Length = 531

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 38/122 (31%), Positives = 59/122 (48%), Gaps = 4/122 (3%)
 Frame = +3

Query: 321 QDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRP 500
           +D   M  L+  L ETLRLYP VP  +R + +EI +  +G   P  T  V   Y++ R P
Sbjct: 378 KDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEV--DGFLFPKNTQFVFCHYEVSRDP 435

Query: 501 DVY----QIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFYNFE 668
             +      Q +  L  S    P       S  F  G R+C+GR+ A L+++++L    +
Sbjct: 436 TAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQ 495

Query: 669 KF 674
           K+
Sbjct: 496 KY 497


>AL358790-3|CAI52498.1|  508|Homo sapiens cytochrome P450, family
           17, subfamily A, polypeptide 1 protein.
          Length = 508

 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 4/148 (2%)
 Frame = +3

Query: 243 YSSRIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVP-IIARQVNQE 419
           ++ +++ K+ EE+DQ  G S  P T  D   +  LE  + E LRL P  P +I  + N +
Sbjct: 320 HNPQVKKKLYEEIDQNVGFSRTP-TISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVD 378

Query: 420 ITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL---F 590
            ++      +  GT ++I  + LH     +  Q +  +   F N   T +I  S     F
Sbjct: 379 SSIGEFA--VDKGTEVIINLWALHHNEKEWH-QPDQFMPERFLNPAGTQLISPSVSYLPF 435

Query: 591 QLGPRSCVGRKYAMLKLKVILFYNFEKF 674
             GPRSC+G   A  +L +I+ +  ++F
Sbjct: 436 GAGPRSCIGEILARQELFLIMAWLLQRF 463


>BC032322-1|AAH32322.1|  509|Homo sapiens cytochrome P450, family
           51, subfamily A, polypeptide 1 protein.
          Length = 509

 Score = 54.4 bits (125), Expect = 4e-07
 Identities = 34/132 (25%), Positives = 60/132 (45%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K   E   + G++  P+T+    ++  L+RC+ ETLRL PPV I+ R      T+  
Sbjct: 339 LQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPVMIMMRMARTPQTVA- 397

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G  IP G  + ++     R  D +  + +       ++ P +        F  G   C+
Sbjct: 398 -GYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI 456

Query: 615 GRKYAMLKLKVI 650
           G  +A +++K I
Sbjct: 457 GENFAYVQIKTI 468


>U51692-1|AAC50951.1|  503|Homo sapiens lanosterol 14-alpha
           demethylase protein.
          Length = 503

 Score = 54.0 bits (124), Expect = 5e-07
 Identities = 33/132 (25%), Positives = 60/132 (45%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K   E   + G++  P+T+    ++  L+RC+ ETLRL PP+ I+ R      T+  
Sbjct: 333 LQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIRETLRLRPPIMIMMRMARTPQTVA- 391

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G  IP G  + ++     R  D +  + +       ++ P +        F  G   C+
Sbjct: 392 -GYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI 450

Query: 615 GRKYAMLKLKVI 650
           G  +A +++K I
Sbjct: 451 GENFAYVQIKTI 462


>U23942-1|AAB39951.1|  509|Homo sapiens lanosterol 14-demethylase
           cytochrome P450 protein.
          Length = 509

 Score = 54.0 bits (124), Expect = 5e-07
 Identities = 33/132 (25%), Positives = 60/132 (45%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K   E   + G++  P+T+    ++  L+RC+ ETLRL PP+ I+ R      T+  
Sbjct: 339 LQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVA- 397

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G  IP G  + ++     R  D +  + +       ++ P +        F  G   C+
Sbjct: 398 -GYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI 456

Query: 615 GRKYAMLKLKVI 650
           G  +A +++K I
Sbjct: 457 GENFAYVQIKTI 468


>D55653-1|BAA09512.1|  509|Homo sapiens lanosterol 14-demethylase
           protein.
          Length = 509

 Score = 54.0 bits (124), Expect = 5e-07
 Identities = 33/132 (25%), Positives = 60/132 (45%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K   E   + G++  P+T+    ++  L+RC+ ETLRL PP+ I+ R      T+  
Sbjct: 339 LQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVA- 397

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G  IP G  + ++     R  D +  + +       ++ P +        F  G   C+
Sbjct: 398 -GYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI 456

Query: 615 GRKYAMLKLKVI 650
           G  +A +++K I
Sbjct: 457 GENFAYVQIKTI 468


>AC000120-2|AAB46356.1|  509|Homo sapiens unknown protein.
          Length = 509

 Score = 54.0 bits (124), Expect = 5e-07
 Identities = 33/132 (25%), Positives = 60/132 (45%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q K   E   + G++  P+T+    ++  L+RC+ ETLRL PP+ I+ R      T+  
Sbjct: 339 LQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTVA- 397

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCV 614
            G  IP G  + ++     R  D +  + +       ++ P +        F  G   C+
Sbjct: 398 -GYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCI 456

Query: 615 GRKYAMLKLKVI 650
           G  +A +++K I
Sbjct: 457 GENFAYVQIKTI 468


>BC132767-1|AAI32768.1|  544|Homo sapiens cytochrome P450, family 2,
           subfamily U, polypeptide 1 protein.
          Length = 544

 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 37/141 (26%), Positives = 70/141 (49%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q+KV EE++++ G ++R  +  D  +M Y E  +ME  RL   VP+    +  E T+  
Sbjct: 374 VQEKVHEEIERVIG-ANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTV-L 431

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSC 611
            G  IP GT ++   + +HR P +++   +      F +     I   + + F +G R C
Sbjct: 432 QGYTIPKGTLILPNLWSVHRDPAIWEKPEDF-YPNRFLDDQGQLIKKETFIPFGIGKRVC 490

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G + A ++L ++     + F
Sbjct: 491 MGEQLAKMELFLMFVSLMQSF 511


>AY343323-1|AAQ21380.1|  544|Homo sapiens cytochrome P450 protein.
          Length = 544

 Score = 53.6 bits (123), Expect = 6e-07
 Identities = 37/141 (26%), Positives = 70/141 (49%), Gaps = 1/141 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q+KV EE++++ G ++R  +  D  +M Y E  +ME  RL   VP+    +  E T+  
Sbjct: 374 VQEKVHEEIERVIG-ANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTV-L 431

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCL-FQLGPRSC 611
            G  IP GT ++   + +HR P +++   +      F +     I   + + F +G R C
Sbjct: 432 QGYTIPKGTLILPNLWSVHRDPAIWEKPEDF-YPNRFLDDQGQLIKKETFIPFGIGKRVC 490

Query: 612 VGRKYAMLKLKVILFYNFEKF 674
           +G + A ++L ++     + F
Sbjct: 491 MGEQLAKMELFLMFVSLMQSF 511


>M32881-1|AAA35741.1|  503|Homo sapiens protein ( Human steroid
           11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
           ).
          Length = 503

 Score = 50.8 bits (116), Expect = 5e-06
 Identities = 39/122 (31%), Positives = 58/122 (47%), Gaps = 6/122 (4%)
 Frame = +3

Query: 327 TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR---- 494
           T E+  L   L ETLRLYP    + R V+ ++ L      IPAGT + +  Y L R    
Sbjct: 359 TTELPLLRAALKETLRLYPVGLFLERVVSSDLVL--QNYHIPAGTLVQVFLYSLGRNAAL 416

Query: 495 --RPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFYNFE 668
             RP+ Y  Q  L +  S RN       +    F  G R C+GR+ A  ++ ++L +  +
Sbjct: 417 FPRPERYNPQRWLDIRGSGRN-------LHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLK 469

Query: 669 KF 674
           +F
Sbjct: 470 RF 471


>BC067429-1|AAH67429.1|  516|Homo sapiens cytochrome P450, family 1,
           subfamily A, polypeptide 2 protein.
          Length = 516

 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 40/141 (28%), Positives = 70/141 (49%), Gaps = 7/141 (4%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLP 431
           IQ K+ +ELD + G   RP    D  ++ YLE  ++ET R  P +P  I     ++ TL 
Sbjct: 339 IQRKIQKELDTVIGRERRP-RLSDRPQLPYLEAFILETFRHSPFLPFTIPHSTTRDTTL- 396

Query: 432 SNGKKIPAGTTLVIATYKLHRRPDVYQIQTN------LTLTTSFRNVPPTDIIMRSCLFQ 593
            NG  IP    + +  ++++  P++++  +       LT   +  N P ++ +M   LF 
Sbjct: 397 -NGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMM---LFG 452

Query: 594 LGPRSCVGRKYAMLKLKVILF 656
           +G R C+G    + K ++ LF
Sbjct: 453 MGKRRCIGE--VLAKWEIFLF 471


>X54741-1|CAA38539.1|  503|Homo sapiens aldosterone  synthase
           (P-450aldo) protein.
          Length = 503

 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 39/122 (31%), Positives = 56/122 (45%), Gaps = 6/122 (4%)
 Frame = +3

Query: 327 TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR---- 494
           T E+  L   L ETLRLYP    + R V+ ++ L      IPAGT + +  Y L R    
Sbjct: 359 TTELPLLRAALKETLRLYPVGLFLERVVSSDLVL--QNYHIPAGTLVQVFLYSLGRNAAL 416

Query: 495 --RPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFYNFE 668
             RP+ Y  Q  L +  S RN            F  G R C+GR+ A  ++ ++L +  +
Sbjct: 417 FPRPERYNPQRWLDIRGSGRN-------FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLK 469

Query: 669 KF 674
            F
Sbjct: 470 HF 471


>D13752-1|BAA02899.1|  503|Homo sapiens steroid 18-hydroxylase
           protein.
          Length = 503

 Score = 48.8 bits (111), Expect = 2e-05
 Identities = 39/122 (31%), Positives = 56/122 (45%), Gaps = 6/122 (4%)
 Frame = +3

Query: 327 TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR---- 494
           T E+  L   L ETLRLYP    + R V+ ++ L      IPAGT + +  Y L R    
Sbjct: 359 TTELPLLRAALKETLRLYPVGLFLERVVSSDLVL--QNYHIPAGTLVQVFLYSLGRNAAL 416

Query: 495 --RPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFYNFE 668
             RP+ Y  Q  L +  S RN            F  G R C+GR+ A  ++ ++L +  +
Sbjct: 417 FPRPERYNPQRWLDIRGSGRN-------FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLK 469

Query: 669 KF 674
            F
Sbjct: 470 HF 471


>M80646-1|AAA60617.1|  460|Homo sapiens thromboxane synthase
           protein.
          Length = 460

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 28/83 (33%), Positives = 45/83 (54%), Gaps = 1/83 (1%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEV-- 421

Query: 435 NGKKIPAGTTLVIATYKLHRRPD 503
            G++IPAG  L +A   LH  P+
Sbjct: 422 LGQRIPAGAVLEMAVGALHHDPE 444


>AL358613-3|CAH72804.1|  428|Homo sapiens cytochrome P450, family
           26, subfamily A, polypeptide 1 protein.
          Length = 428

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 7/143 (4%)
 Frame = +3

Query: 240 GYSSRIQDKVIEELDQ----IFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQ 407
           G    +  KV EEL         + D  +  +   ++KY+   + ETLRL PPVP   R 
Sbjct: 248 GLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRV 307

Query: 408 VNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFR-NVP-PTDIIMRS 581
             +  T   NG +IP G  ++ +    H   DV +I TN       R  +P P D    S
Sbjct: 308 ALK--TFELNGYQIPKGWNVIYSICDTH---DVAEIFTNKEEFNPDRFMLPHPEDASRFS 362

Query: 582 CL-FQLGPRSCVGRKYAMLKLKV 647
            + F  G RSCVG+++A + LK+
Sbjct: 363 FIPFGGGLRSCVGKEFAKILLKI 385


>AL358613-2|CAH72803.1|  497|Homo sapiens cytochrome P450, family
           26, subfamily A, polypeptide 1 protein.
          Length = 497

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 7/143 (4%)
 Frame = +3

Query: 240 GYSSRIQDKVIEELDQ----IFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQ 407
           G    +  KV EEL         + D  +  +   ++KY+   + ETLRL PPVP   R 
Sbjct: 317 GLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRV 376

Query: 408 VNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFR-NVP-PTDIIMRS 581
             +  T   NG +IP G  ++ +    H   DV +I TN       R  +P P D    S
Sbjct: 377 ALK--TFELNGYQIPKGWNVIYSICDTH---DVAEIFTNKEEFNPDRFMLPHPEDASRFS 431

Query: 582 CL-FQLGPRSCVGRKYAMLKLKV 647
            + F  G RSCVG+++A + LK+
Sbjct: 432 FIPFGGGLRSCVGKEFAKILLKI 454


>AF005418-1|AAB88881.1|  497|Homo sapiens retinoic acid hydroxylase
           protein.
          Length = 497

 Score = 47.2 bits (107), Expect = 6e-05
 Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 7/143 (4%)
 Frame = +3

Query: 240 GYSSRIQDKVIEELDQ----IFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQ 407
           G    +  KV EEL         + D  +  +   ++KY+   + ETLRL PPVP   R 
Sbjct: 317 GLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPPVPGGFRV 376

Query: 408 VNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFR-NVP-PTDIIMRS 581
             +  T   NG +IP G  ++ +    H   DV +I TN       R  +P P D    S
Sbjct: 377 ALK--TFELNGYQIPKGWNVIYSICDTH---DVAEIFTNKEEFNPDRFMLPHPEDASRFS 431

Query: 582 CL-FQLGPRSCVGRKYAMLKLKV 647
            + F  G RSCVG+++A + LK+
Sbjct: 432 FIPFGGGLRSCVGKEFAKILLKI 454


>M24667-1|AAA52148.1|  256|Homo sapiens steroid 11-beta-hydroxylase
           protein.
          Length = 256

 Score = 46.8 bits (106), Expect = 7e-05
 Identities = 39/115 (33%), Positives = 53/115 (46%), Gaps = 6/115 (5%)
 Frame = +3

Query: 327 TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR---- 494
           T E+  L   L ETLRLYP   I+ R V+ ++ L      IPAGT + +  Y L R    
Sbjct: 149 TTELPLLRAALKETLRLYPVGLILERVVSSDLVL--QNYHIPAGTLVRVFLYSLGRNPAL 206

Query: 495 --RPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVIL 653
             RP+ Y  Q  L +  S RN            F  G R C+GR+ A   + ++L
Sbjct: 207 FPRPERYNPQRWLDIKGSGRN-------FYHVPFGFGMRQCLGRRLAEADMLLLL 254


>X55764-1|CAA39290.1|  503|Homo sapiens protein ( Human mRNA for
           cytochrome P-450 (11 Beta). ).
          Length = 503

 Score = 46.4 bits (105), Expect = 1e-04
 Identities = 38/117 (32%), Positives = 54/117 (46%), Gaps = 6/117 (5%)
 Frame = +3

Query: 327 TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR---- 494
           T E+  L   L ETLRLYP    + R V+ ++ L      IPAGT + +  Y L R    
Sbjct: 359 TTELPLLRAALKETLRLYPVGLFLERVVSSDLVL--QNYHIPAGTLVRVFLYSLGRNPAL 416

Query: 495 --RPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFY 659
             RP+ Y  Q  L +  S RN            F  G R C+GR+ A  ++ ++L +
Sbjct: 417 FPRPERYNPQRWLDIRGSGRN-------FYHVPFGFGMRQCLGRRLAEAEMLLLLHH 466


>U37143-1|AAC50370.2|  502|Homo sapiens cytochrome P450
           monooxygenase CYP2J2 protein.
          Length = 502

 Score = 45.6 bits (103), Expect = 2e-04
 Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 3/143 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLP 431
           IQ+KV  E+D++ G   +P T      M Y    + E  R+   +P+ + R+V  + TL 
Sbjct: 333 IQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLA 391

Query: 432 SNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRN--VPPTDIIMRSCLFQLGPR 605
             G  +P GT ++     LHR P  +             N      +  M    F +G R
Sbjct: 392 --GYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMP---FSIGKR 446

Query: 606 SCVGRKYAMLKLKVILFYNFEKF 674
           +C+G + A  +L +      +KF
Sbjct: 447 ACLGEQLARTELFIFFTSLMQKF 469


>BC039307-1|AAH39307.1|  372|Homo sapiens cytochrome P450, family
           27, subfamily C, polypeptide 1 protein.
          Length = 372

 Score = 45.6 bits (103), Expect = 2e-04
 Identities = 37/147 (25%), Positives = 63/147 (42%), Gaps = 1/147 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q  V  E+ +  G+   P T  D  ++  +   L ETLRL+P +P   R   +++ +  
Sbjct: 202 VQQTVYREIVKNLGERHVP-TAADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVI-- 258

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDII-MRSCLFQLGPRSC 611
            G  IP GT L +  Y    + + +            R      +    S  F  G RSC
Sbjct: 259 GGYLIPKGTQLALCHYATSYQDENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSC 318

Query: 612 VGRKYAMLKLKVILFYNFEKFPSNISS 692
           +GR+ A L++ +++    + F    SS
Sbjct: 319 IGRRIAELEIHLVVIQLLQHFEIKTSS 345


>BC032594-1|AAH32594.1|  502|Homo sapiens cytochrome P450, family 2,
           subfamily J, polypeptide 2 protein.
          Length = 502

 Score = 45.6 bits (103), Expect = 2e-04
 Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 3/143 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLP 431
           IQ+KV  E+D++ G   +P T      M Y    + E  R+   +P+ + R+V  + TL 
Sbjct: 333 IQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLA 391

Query: 432 SNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRN--VPPTDIIMRSCLFQLGPR 605
             G  +P GT ++     LHR P  +             N      +  M    F +G R
Sbjct: 392 --GYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMP---FSIGKR 446

Query: 606 SCVGRKYAMLKLKVILFYNFEKF 674
           +C+G + A  +L +      +KF
Sbjct: 447 ACLGEQLARTELFIFFTSLMQKF 469


>AY426985-1|AAQ93356.1|  502|Homo sapiens cytochrome P450, family 2,
           subfamily J, polypeptide 2 protein.
          Length = 502

 Score = 45.6 bits (103), Expect = 2e-04
 Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 3/143 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLP 431
           IQ+KV  E+D++ G   +P T      M Y    + E  R+   +P+ + R+V  + TL 
Sbjct: 333 IQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLA 391

Query: 432 SNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRN--VPPTDIIMRSCLFQLGPR 605
             G  +P GT ++     LHR P  +             N      +  M    F +G R
Sbjct: 392 --GYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMP---FSIGKR 446

Query: 606 SCVGRKYAMLKLKVILFYNFEKF 674
           +C+G + A  +L +      +KF
Sbjct: 447 ACLGEQLARTELFIFFTSLMQKF 469


>AK131190-1|BAD18388.1|  372|Homo sapiens .-.-).  protein.
          Length = 372

 Score = 45.6 bits (103), Expect = 2e-04
 Identities = 37/147 (25%), Positives = 63/147 (42%), Gaps = 1/147 (0%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           +Q  V  E+ +  G+   P T  D  ++  +   L ETLRL+P +P   R   +++ +  
Sbjct: 202 VQQTVYREIVKNLGERHVP-TAADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVI-- 258

Query: 435 NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDII-MRSCLFQLGPRSC 611
            G  IP GT L +  Y    + + +            R      +    S  F  G RSC
Sbjct: 259 GGYLIPKGTQLALCHYATSYQDENFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSC 318

Query: 612 VGRKYAMLKLKVILFYNFEKFPSNISS 692
           +GR+ A L++ +++    + F    SS
Sbjct: 319 IGRRIAELEIHLVVIQLLQHFEIKTSS 345


>AK090886-1|BAC03539.1|  337|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
           Homo sapiens cholesterol 24-hydroxylase mRNA. ).
          Length = 337

 Score = 45.6 bits (103), Expect = 2e-04
 Identities = 36/126 (28%), Positives = 60/126 (47%)
 Frame = +3

Query: 276 ELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPA 455
           E+D++ G S R + F+D   ++YL + L E+LRLYPP     R + +E  +         
Sbjct: 178 EVDEVIG-SKRYLDFEDLGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDG------- 229

Query: 456 GTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAML 635
                 +TY + R  D Y  +  LT                   F LG RSC+G+++A +
Sbjct: 230 -----FSTYVMGRM-DTY-FEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQM 282

Query: 636 KLKVIL 653
           ++KV++
Sbjct: 283 EVKVVM 288


>AF272142-1|AAM44456.1|  502|Homo sapiens cytochrome P450 protein.
          Length = 502

 Score = 45.6 bits (103), Expect = 2e-04
 Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 3/143 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLP 431
           IQ+KV  E+D++ G   +P T      M Y    + E  R+   +P+ + R+V  + TL 
Sbjct: 333 IQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLA 391

Query: 432 SNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRN--VPPTDIIMRSCLFQLGPR 605
             G  +P GT ++     LHR P  +             N      +  M    F +G R
Sbjct: 392 --GYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMP---FSIGKR 446

Query: 606 SCVGRKYAMLKLKVILFYNFEKF 674
           +C+G + A  +L +      +KF
Sbjct: 447 ACLGEQLARTELFIFFTSLMQKF 469


>AB080265-1|BAB85489.1|  502|Homo sapiens cytochrome P450 2J2
           protein.
          Length = 502

 Score = 45.2 bits (102), Expect = 2e-04
 Identities = 37/143 (25%), Positives = 61/143 (42%), Gaps = 3/143 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITLP 431
           IQ+KV  E+D++ G   +P T      M Y    + E  R+   +P+ + R+V  + TL 
Sbjct: 333 IQEKVQVEIDRVIGQGQQPSTAARE-SMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLA 391

Query: 432 SNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRN--VPPTDIIMRSCLFQLGPR 605
             G  +P GT ++     LHR P  +             N      +  M    F +G R
Sbjct: 392 --GYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMP---FSIGKR 446

Query: 606 SCVGRKYAMLKLKVILFYNFEKF 674
           +C+G + A  +L +      +KF
Sbjct: 447 ACLGEQLARTELFIFFTSLMQKF 469


>X05367-1|CAA28965.1|  521|Homo sapiens desmolase protein.
          Length = 521

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 32/110 (29%), Positives = 50/110 (45%)
 Frame = +3

Query: 345 LERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTN 524
           L+  + ETLRL+P    + R +  ++ L      IPA T + +A Y L R P  +    N
Sbjct: 377 LKASIKETLRLHPISVTLQRYLVNDLVL--RDYMIPAKTLVQVAIYALGREPTFFFDPEN 434

Query: 525 LTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFYNFEKF 674
               T + +        R+  F  G R C+GR+ A L++ + L    E F
Sbjct: 435 FD-PTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENF 483


>M32879-1|AAA52149.1|  503|Homo sapiens CYP11B1 protein.
          Length = 503

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
 Frame = +3

Query: 327 TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR---- 494
           T E+  L   L ETLRLYP    + R  + ++ L      IPAGT + +  Y L R    
Sbjct: 359 TTELPLLRAALKETLRLYPVGLFLERVASSDLVL--QNYHIPAGTLVRVFLYSLGRNPAL 416

Query: 495 --RPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFY 659
             RP+ Y  Q  L +  S RN            F  G R C+GR+ A  ++ ++L +
Sbjct: 417 FPRPERYNPQRWLDIRGSGRN-------FYHVPFGFGMRQCLGRRLAEAEMLLLLHH 466


>M28253-1|AAA36404.1|  239|Homo sapiens cytochrome P-450-scc
           protein.
          Length = 239

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 32/110 (29%), Positives = 50/110 (45%)
 Frame = +3

Query: 345 LERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTN 524
           L+  + ETLRL+P    + R +  ++ L      IPA T + +A Y L R P  +    N
Sbjct: 95  LKASIKETLRLHPISVTLQRYLVNDLVL--RDYMIPAKTLVQVAIYALGREPTFFFDPEN 152

Query: 525 LTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFYNFEKF 674
               T + +        R+  F  G R C+GR+ A L++ + L    E F
Sbjct: 153 FD-PTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENF 201


>M14565-1|AAA52162.1|  521|Homo sapiens CYP11A protein.
          Length = 521

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 32/110 (29%), Positives = 50/110 (45%)
 Frame = +3

Query: 345 LERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTN 524
           L+  + ETLRL+P    + R +  ++ L      IPA T + +A Y L R P  +    N
Sbjct: 377 LKASIKETLRLHPISVTLQRYLVNDLVL--RDYMIPAKTLVQVAIYALGREPTFFFDPEN 434

Query: 525 LTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFYNFEKF 674
               T + +        R+  F  G R C+GR+ A L++ + L    E F
Sbjct: 435 FD-PTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENF 483


>BC096287-1|AAH96287.1|  503|Homo sapiens cytochrome P450, family
           11, subfamily B, polypeptide 1 protein.
          Length = 503

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
 Frame = +3

Query: 327 TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR---- 494
           T E+  L   L ETLRLYP    + R  + ++ L      IPAGT + +  Y L R    
Sbjct: 359 TTELPLLRAALKETLRLYPVGLFLERVASSDLVL--QNYHIPAGTLVRVFLYSLGRNPAL 416

Query: 495 --RPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFY 659
             RP+ Y  Q  L +  S RN            F  G R C+GR+ A  ++ ++L +
Sbjct: 417 FPRPERYNPQRWLDIRGSGRN-------FYHVPFGFGMRQCLGRRLAEAEMLLLLHH 466


>BC096285-1|AAH96285.1|  574|Homo sapiens CYP11B1 protein protein.
          Length = 574

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
 Frame = +3

Query: 327 TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR---- 494
           T E+  L   L ETLRLYP    + R  + ++ L      IPAGT + +  Y L R    
Sbjct: 430 TTELPLLRAALKETLRLYPVGLFLERVASSDLVL--QNYHIPAGTLVRVFLYSLGRNPAL 487

Query: 495 --RPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFY 659
             RP+ Y  Q  L +  S RN            F  G R C+GR+ A  ++ ++L +
Sbjct: 488 FPRPERYNPQRWLDIRGSGRN-------FYHVPFGFGMRQCLGRRLAEAEMLLLLHH 537


>BC032329-1|AAH32329.1|  521|Homo sapiens cytochrome P450, family
           11, subfamily A, polypeptide 1 protein.
          Length = 521

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 32/110 (29%), Positives = 50/110 (45%)
 Frame = +3

Query: 345 LERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTN 524
           L+  + ETLRL+P    + R +  ++ L      IPA T + +A Y L R P  +    N
Sbjct: 377 LKASIKETLRLHPISVTLQRYLVNDLVL--RDYMIPAKTLVQVAIYALGREPTFFFDPEN 434

Query: 525 LTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFYNFEKF 674
               T + +        R+  F  G R C+GR+ A L++ + L    E F
Sbjct: 435 FD-PTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENF 483


>AF478474-1|AAL84813.1|  503|Homo sapiens mutated cytochrome
           P-450c11 protein protein.
          Length = 503

 Score = 44.8 bits (101), Expect = 3e-04
 Identities = 37/117 (31%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
 Frame = +3

Query: 327 TLEMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHR---- 494
           T E+  L   L ETLRLYP    + R  + ++ L      IPAGT + +  Y L R    
Sbjct: 359 TTELPLLRAALKETLRLYPVGLFLERVASSDLVL--QNYHIPAGTLVRVFLYSLGRNPAL 416

Query: 495 --RPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVILFY 659
             RP+ Y  Q  L +  S RN            F  G R C+GR+ A  ++ ++L +
Sbjct: 417 FPRPERYNPQRWLDIRGSGRN-------FYHVPFGFGMRQCLGRRLAEAEMLLLLHH 466


>AY288916-1|AAP31972.1|  508|Homo sapiens cytochrome P450, family
           27, subfamily B, polypeptide 1 protein.
          Length = 508

 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 51/107 (47%)
 Frame = +3

Query: 333 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQ 512
           ++  L+  + E LRLYP VP  +R  +++I +      IP  T + +  Y   R P  + 
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFP 423

Query: 513 IQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVIL 653
            + N      +    PT     S  F  G RSC+GR+ A L+L++ L
Sbjct: 424 -EPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMAL 469


>AF256213-1|AAG00416.1|  508|Homo sapiens 25- hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 51/107 (47%)
 Frame = +3

Query: 333 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQ 512
           ++  L+  + E LRLYP VP  +R  +++I +      IP  T + +  Y   R P  + 
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFP 423

Query: 513 IQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVIL 653
            + N      +    PT     S  F  G RSC+GR+ A L+L++ L
Sbjct: 424 -EPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMAL 469


>AF246895-1|AAF64299.1|  508|Homo sapiens 25-hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 51/107 (47%)
 Frame = +3

Query: 333 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQ 512
           ++  L+  + E LRLYP VP  +R  +++I +      IP  T + +  Y   R P  + 
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFP 423

Query: 513 IQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVIL 653
            + N      +    PT     S  F  G RSC+GR+ A L+L++ L
Sbjct: 424 -EPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMAL 469


>AF027152-1|AAC51854.1|  508|Homo sapiens P450 25-hydroxyvitamin D-1
           alpha hydroxylase protein.
          Length = 508

 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 51/107 (47%)
 Frame = +3

Query: 333 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQ 512
           ++  L+  + E LRLYP VP  +R  +++I +      IP  T + +  Y   R P  + 
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFP 423

Query: 513 IQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVIL 653
            + N      +    PT     S  F  G RSC+GR+ A L+L++ L
Sbjct: 424 -EPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMAL 469


>AF020192-1|AAC51853.1|  508|Homo sapiens 25-hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 51/107 (47%)
 Frame = +3

Query: 333 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQ 512
           ++  L+  + E LRLYP VP  +R  +++I +      IP  T + +  Y   R P  + 
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFP 423

Query: 513 IQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVIL 653
            + N      +    PT     S  F  G RSC+GR+ A L+L++ L
Sbjct: 424 -EPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMAL 469


>AB006987-1|BAA23418.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1-alpha-hydroxylase protein.
          Length = 508

 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 51/107 (47%)
 Frame = +3

Query: 333 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQ 512
           ++  L+  + E LRLYP VP  +R  +++I +      IP  T + +  Y   R P  + 
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFP 423

Query: 513 IQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVIL 653
            + N      +    PT     S  F  G RSC+GR+ A L+L++ L
Sbjct: 424 -EPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMAL 469


>AB005990-1|BAA22657.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1alpha-hydroxylase protein.
          Length = 508

 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 51/107 (47%)
 Frame = +3

Query: 333 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQ 512
           ++  L+  + E LRLYP VP  +R  +++I +      IP  T + +  Y   R P  + 
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFP 423

Query: 513 IQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVIL 653
            + N      +    PT     S  F  G RSC+GR+ A L+L++ L
Sbjct: 424 -EPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMAL 469


>AB005989-1|BAA22656.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1alpha-hydroxylase protein.
          Length = 508

 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 51/107 (47%)
 Frame = +3

Query: 333 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQ 512
           ++  L+  + E LRLYP VP  +R  +++I +      IP  T + +  Y   R P  + 
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFP 423

Query: 513 IQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVIL 653
            + N      +    PT     S  F  G RSC+GR+ A L+L++ L
Sbjct: 424 -EPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMAL 469


>AB005038-1|BAA23416.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1-alpha-hydroxylase protein.
          Length = 508

 Score = 44.0 bits (99), Expect = 5e-04
 Identities = 32/107 (29%), Positives = 51/107 (47%)
 Frame = +3

Query: 333 EMKYLERCLMETLRLYPPVPIIARQVNQEITLPSNGKKIPAGTTLVIATYKLHRRPDVYQ 512
           ++  L+  + E LRLYP VP  +R  +++I +      IP  T + +  Y   R P  + 
Sbjct: 366 QLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHV--GDYIIPKNTLVTLCHYATSRDPAQFP 423

Query: 513 IQTNLTLTTSFRNVPPTDIIMRSCLFQLGPRSCVGRKYAMLKLKVIL 653
            + N      +    PT     S  F  G RSC+GR+ A L+L++ L
Sbjct: 424 -EPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMAL 469


>X02612-1|CAA26458.1|  512|Homo sapiens cytochrome P(1)-450 protein.
          Length = 512

 Score = 43.2 bits (97), Expect = 0.001
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITL 428
           R+Q K+ EELD + G S RP    D   + Y+E  ++ET R    VP  I     ++ +L
Sbjct: 338 RVQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSLVPFTIPHSTTRDTSL 396

Query: 429 PSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIM--RSCLFQLGP 602
              G  IP G  + +  ++++    ++   +              D ++  +  +F +G 
Sbjct: 397 --KGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGK 454

Query: 603 RSCVGRKYAMLKLKVILF 656
           R C+G   A  + +V LF
Sbjct: 455 RKCIGETVA--RWEVFLF 470


>X04300-1|CAA27843.1|  512|Homo sapiens P-450 c protein.
          Length = 512

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITL 428
           R+Q K+ EELD + G S RP    D   + Y+E  ++ET R    VP  I     ++ +L
Sbjct: 338 RVQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSL 396

Query: 429 PSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIM--RSCLFQLGP 602
              G  IP G  + +  ++++    ++   +              D ++  +  +F +G 
Sbjct: 397 --KGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGK 454

Query: 603 RSCVGRKYAMLKLKVILF 656
           R C+G   A  + +V LF
Sbjct: 455 RKCIGETIA--RWEVFLF 470


>M12079-1|AAA52152.1|  191|Homo sapiens POR protein.
          Length = 191

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITL 428
           R+Q K+ EELD + G S RP    D   + Y+E  ++ET R    VP  I     ++ +L
Sbjct: 44  RVQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSL 102

Query: 429 PSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIM--RSCLFQLGP 602
              G  IP G  + +  ++++    ++   +              D ++  +  +F +G 
Sbjct: 103 --KGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGK 160

Query: 603 RSCVGRKYAMLKLKVILF 656
           R C+G   A  + +V LF
Sbjct: 161 RKCIGETVA--RWEVFLF 176


>K03191-1|AAA52139.1|  512|Homo sapiens CYP1A1 protein.
          Length = 512

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITL 428
           R+Q K+ EELD + G S RP    D   + Y+E  ++ET R    VP  I     ++ +L
Sbjct: 338 RVQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSL 396

Query: 429 PSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIM--RSCLFQLGP 602
              G  IP G  + +  ++++    ++   +              D ++  +  +F +G 
Sbjct: 397 --KGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGK 454

Query: 603 RSCVGRKYAMLKLKVILF 656
           R C+G   A  + +V LF
Sbjct: 455 RKCIGETVA--RWEVFLF 470


>EF094025-1|ABK41999.1|  512|Homo sapiens cytochrome P450, family 1,
           subfamily A, polypeptide 1 protein.
          Length = 512

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITL 428
           R+Q K+ EELD + G S RP    D   + Y+E  ++ET R    VP  I     ++ +L
Sbjct: 338 RVQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSL 396

Query: 429 PSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIM--RSCLFQLGP 602
              G  IP G  + +  ++++    ++   +              D ++  +  +F +G 
Sbjct: 397 --KGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGK 454

Query: 603 RSCVGRKYAMLKLKVILF 656
           R C+G   A  + +V LF
Sbjct: 455 RKCIGETIA--RWEVFLF 470


>BC023019-1|AAH23019.1|  512|Homo sapiens cytochrome P450, family 1,
           subfamily A, polypeptide 1 protein.
          Length = 512

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITL 428
           R+Q K+ EELD + G S RP    D   + Y+E  ++ET R    VP  I     ++ +L
Sbjct: 338 RVQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSL 396

Query: 429 PSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIM--RSCLFQLGP 602
              G  IP G  + +  ++++    ++   +              D ++  +  +F +G 
Sbjct: 397 --KGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGK 454

Query: 603 RSCVGRKYAMLKLKVILF 656
           R C+G   A  + +V LF
Sbjct: 455 RKCIGETIA--RWEVFLF 470


>AY310359-1|AAQ76692.1|  484|Homo sapiens cytochrome P450 1A1
           variant protein.
          Length = 484

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITL 428
           R+Q K+ EELD + G S RP    D   + Y+E  ++ET R    VP  I     ++ +L
Sbjct: 310 RVQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSL 368

Query: 429 PSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIM--RSCLFQLGP 602
              G  IP G  + +  ++++    ++   +              D ++  +  +F +G 
Sbjct: 369 --KGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGK 426

Query: 603 RSCVGRKYAMLKLKVILF 656
           R C+G   A  + +V LF
Sbjct: 427 RKCIGETIA--RWEVFLF 442


>AM236047-1|CAJ84704.1|  251|Homo sapiens cytochrome P450 1A1
           protein.
          Length = 251

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITL 428
           R+Q K+ EELD + G S RP    D   + Y+E  ++ET R    VP  I     ++ +L
Sbjct: 77  RVQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSL 135

Query: 429 PSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIM--RSCLFQLGP 602
              G  IP G  + +  ++++    ++   +              D ++  +  +F +G 
Sbjct: 136 --KGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGK 193

Query: 603 RSCVGRKYAMLKLKVILF 656
           R C+G   A  + +V LF
Sbjct: 194 RKCIGETIA--RWEVFLF 209


>AK223113-1|BAD96833.1|  512|Homo sapiens cytochrome P450, family 1,
           subfamily A, polypeptide 1 variant protein.
          Length = 512

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITL 428
           R+Q K+ EELD + G S RP    D   + Y+E  ++ET R    VP  I     ++ +L
Sbjct: 338 RVQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSL 396

Query: 429 PSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIM--RSCLFQLGP 602
              G  IP G  + +  ++++    ++   +              D ++  +  +F +G 
Sbjct: 397 --KGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGK 454

Query: 603 RSCVGRKYAMLKLKVILF 656
           R C+G   A  + +V LF
Sbjct: 455 RKCIGETIA--RWEVFLF 470


>AK223108-1|BAD96828.1|  512|Homo sapiens cytochrome P450, family 1,
           subfamily A, polypeptide 1 variant protein.
          Length = 512

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 41/142 (28%), Positives = 63/142 (44%), Gaps = 7/142 (4%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITL 428
           R+Q K+ EELD + G S RP    D   + Y+E  ++ET R    VP  I     ++ +L
Sbjct: 338 RVQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSL 396

Query: 429 PSNGKKIPAGTTLVIATY------KLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLF 590
              G  IP G  + +  +      KL   P  +  +  LT   +   V    +I    +F
Sbjct: 397 --KGFYIPKGRCVFVNQWQIDHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVI----IF 450

Query: 591 QLGPRSCVGRKYAMLKLKVILF 656
            +G R C+G   A  + +V LF
Sbjct: 451 GMGKRKCIGETIA--RWEVFLF 470


>AF253322-1|AAK25727.1|  512|Homo sapiens cytochrome P450 protein.
          Length = 512

 Score = 42.7 bits (96), Expect = 0.001
 Identities = 35/138 (25%), Positives = 62/138 (44%), Gaps = 3/138 (2%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPI-IARQVNQEITL 428
           R+Q K+ EELD + G S RP    D   + Y+E  ++ET R    VP  I     ++ +L
Sbjct: 338 RVQRKIQEELDTVIGRSRRP-RLSDRSHLPYMEAFILETFRHSSFVPFTIPHSTTRDTSL 396

Query: 429 PSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIM--RSCLFQLGP 602
              G  IP G  + +  ++++    ++   +              D ++  +  +F +G 
Sbjct: 397 --KGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGAIDKVLSEKVIIFGMGK 454

Query: 603 RSCVGRKYAMLKLKVILF 656
           R C+G   A  + +V LF
Sbjct: 455 RKCIGETIA--RWEVFLF 470


>M28548-1|AAA52065.1|  495|Homo sapiens protein ( Human mutant
           21-hydroxylase B gene, complete cds. ).
          Length = 495

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 314 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 370

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 371 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 426

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 427 RVCLGEPLARLELFVVL 443


>M26856-1|AAA52064.1|  495|Homo sapiens protein ( Human
           21-hydroxylase B gene, complete cds. ).
          Length = 495

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 314 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 370

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 371 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 426

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 427 RVCLGEPLARLELFVVL 443


>M21550-1|AAA52063.1|  495|Homo sapiens CYP21 protein.
          Length = 495

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 314 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 370

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 371 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 426

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 427 RVCLGEPLARLELFVVL 443


>M13936-1|AAA59695.1|  494|Homo sapiens CYP21P protein.
          Length = 494

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>BX679671-8|CAM26070.1|  494|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 494

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>BX679671-7|CAM26071.1|  464|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 464

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 283 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 339

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 340 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 395

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 396 RVCLGEPLARLELFVVL 412


>BC125182-1|AAI25183.1|  494|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 494

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>BC125181-1|AAI25182.1|  495|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 495

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 314 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 370

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 371 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 426

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 427 RVCLGEPLARLELFVVL 443


>BC010358-1|AAH10358.1|  469|Homo sapiens cytochrome P450, family
           39, subfamily A, polypeptide 1 protein.
          Length = 469

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 35/149 (23%), Positives = 74/149 (49%), Gaps = 5/149 (3%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDS--DRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEIT 425
           I   ++E +  +FG +  D+    +D LE +  ++ C++ET+RL  P  +I R+V + + 
Sbjct: 295 IHKAIMEGISSVFGKAGKDKIKVSEDDLENLLLIKWCVLETIRLKAP-GVITRKVVKPVE 353

Query: 426 LPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFR--NVPPTDIIMRSCLFQLG 599
           + +    IP+G  L+++ + LHR P  Y  +  L     ++  N+     +     F  G
Sbjct: 354 ILNY--IIPSGDLLMLSPFWLHRNPK-YFPEPELFKPERWKKANLEKHSFLDCFMAFGSG 410

Query: 600 PRSCVGRKYAMLKLKVILFYNFEKFPSNI 686
              C  R +A+L++++ +     K+  ++
Sbjct: 411 KFQCPARWFALLEVQMCIILILYKYDCSL 439


>AM183951-1|CAJ75805.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>AM183949-1|CAJ75803.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>AM183948-1|CAJ75802.1|  494|Homo sapiens steroid 21-hydroxylase
           protein.
          Length = 494

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>AM183947-1|CAJ75801.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>AM183946-1|CAJ75800.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>AM183945-1|CAJ75799.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>AM086565-1|CAJ31104.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGTHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>AM086564-1|CAJ31103.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>AL929593-2|CAI41778.1|  465|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 465

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 284 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 340

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 341 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 396

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 397 RVCLGEPLARLELFVVL 413


>AL929593-1|CAI41779.1|  495|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 495

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 314 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 370

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 371 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 426

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 427 RVCLGEPLARLELFVVL 443


>AL662849-19|CAI17480.1|  465|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 465

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 284 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 340

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 341 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 396

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 397 RVCLGEPLARLELFVVL 413


>AL662849-18|CAI17479.1|  495|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 495

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 314 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 370

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 371 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 426

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 427 RVCLGEPLARLELFVVL 443


>AL645922-24|CAI41754.1|  495|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 495

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 314 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 370

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 371 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 426

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 427 RVCLGEPLARLELFVVL 443


>AL645922-23|CAI41755.1|  465|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 465

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 284 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 340

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 341 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 396

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 397 RVCLGEPLARLELFVVL 413


>AL591242-1|CAH73899.1|  469|Homo sapiens cytochrome P450, family
           39, subfamily A, polypeptide 1 protein.
          Length = 469

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 35/149 (23%), Positives = 74/149 (49%), Gaps = 5/149 (3%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDS--DRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEIT 425
           I   ++E +  +FG +  D+    +D LE +  ++ C++ET+RL  P  +I R+V + + 
Sbjct: 295 IHKAIMEGISSVFGKAGKDKIKVSEDDLENLLLIKWCVLETIRLKAP-GVITRKVVKPVE 353

Query: 426 LPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFR--NVPPTDIIMRSCLFQLG 599
           + +    IP+G  L+++ + LHR P  Y  +  L     ++  N+     +     F  G
Sbjct: 354 ILNY--IIPSGDLLMLSPFWLHRNPK-YFPEPELFKPERWKKANLEKHSFLDCFMAFGSG 410

Query: 600 PRSCVGRKYAMLKLKVILFYNFEKFPSNI 686
              C  R +A+L++++ +     K+  ++
Sbjct: 411 KFQCPARWFALLEVQMCIILILYKYDCSL 439


>AL049547-7|CAB89301.1|  495|Homo sapiens dJ34F7.3 (cytochrome P450,
           subfamily XXIA (steroid 21-hydroxylase, congenital a
           protein.
          Length = 495

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 314 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 370

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 371 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 426

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 427 RVCLGEPLARLELFVVL 443


>AL035670-1|CAI20276.1|  469|Homo sapiens cytochrome P450, family
           39, subfamily A, polypeptide 1 protein.
          Length = 469

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 35/149 (23%), Positives = 74/149 (49%), Gaps = 5/149 (3%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDS--DRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEIT 425
           I   ++E +  +FG +  D+    +D LE +  ++ C++ET+RL  P  +I R+V + + 
Sbjct: 295 IHKAIMEGISSVFGKAGKDKIKVSEDDLENLLLIKWCVLETIRLKAP-GVITRKVVKPVE 353

Query: 426 LPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFR--NVPPTDIIMRSCLFQLG 599
           + +    IP+G  L+++ + LHR P  Y  +  L     ++  N+     +     F  G
Sbjct: 354 ILNY--IIPSGDLLMLSPFWLHRNPK-YFPEPELFKPERWKKANLEKHSFLDCFMAFGSG 410

Query: 600 PRSCVGRKYAMLKLKVILFYNFEKFPSNI 686
              C  R +A+L++++ +     K+  ++
Sbjct: 411 KFQCPARWFALLEVQMCIILILYKYDCSL 439


>AK054616-1|BAB70774.1|  465|Homo sapiens protein ( Homo sapiens
           cDNA FLJ30054 fis, clone ADRGL1000160, highly similar to
           CYTOCHROME P450 XXIB (EC 1.14.99.10). ).
          Length = 465

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 284 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 340

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 341 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 396

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 397 RVCLGEPLARLELFVVL 413


>AF237982-1|AAF63329.1|  469|Homo sapiens oxysterol
           7alpha-hydroxylase protein.
          Length = 469

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 36/149 (24%), Positives = 73/149 (48%), Gaps = 5/149 (3%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGDS--DRPVTFQDTLEMKYLER-CLMETLRLYPPVPIIARQVNQEIT 425
           I   ++E +  +FG +  D+    +D LE   L + C++ET+RL  P  +I R+V + + 
Sbjct: 295 IHKAIMEGISSVFGKAGKDKIKVSEDDLEKLLLIKWCVLETIRLKAP-GVITRKVVKPVE 353

Query: 426 LPSNGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFR--NVPPTDIIMRSCLFQLG 599
           + +    IP+G  L+++ + LHR P  Y  +  L     ++  N+     +     F  G
Sbjct: 354 ILNY--IIPSGDLLMLSPFWLHRNPK-YFPEPELFKPERWKKANLEKHSFLDCFMAFGSG 410

Query: 600 PRSCVGRKYAMLKLKVILFYNFEKFPSNI 686
              C  R +A+L++++ +     K+  ++
Sbjct: 411 KFQCPARWFALLEVQMCIILILYKYDCSL 439


>AF077974-1|AAD45405.1|  403|Homo sapiens cytochrome P450
           21-hydroxylase protein.
          Length = 403

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 222 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 278

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 279 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 334

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 335 RVCLGEPLARLELFVVL 351


>AF019413-2|AAB67982.1|  495|Homo sapiens cytochrome P450
           21-hydroxylase protein.
          Length = 495

 Score = 41.5 bits (93), Expect = 0.003
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 314 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 370

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 371 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 426

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 427 RVCLGEPLARLELFVVL 443


>X58906-1|CAA41709.1|  495|Homo sapiens steroid 21-monooxygenase
           protein.
          Length = 495

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+    +    T 
Sbjct: 314 IQQRLQEELDHELGPGASSSRVPYKDHARLPLLNATIAEVLRLRPVVPL---ALPHRTTR 370

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 371 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 426

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 427 RVCLGEPLARLELFVVL 443


>L36085-1|AAC01761.1|  441|Homo sapiens thromboxane A2 synthase
           protein.
          Length = 441

 Score = 41.1 bits (92), Expect = 0.004
 Identities = 25/74 (33%), Positives = 41/74 (55%), Gaps = 1/74 (1%)
 Frame = +3

Query: 258 QDKVIEELDQIFGDSDRPVTFQDTLE-MKYLERCLMETLRLYPPVPIIARQVNQEITLPS 434
           Q+K++ E+D +F +      F    E + YL+  + ETLR+YPP     R+  Q+  +  
Sbjct: 365 QEKLLREVD-VFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEV-- 421

Query: 435 NGKKIPAGTTLVIA 476
            G++IPAG  L +A
Sbjct: 422 LGQRIPAGAVLEMA 435


>BC109084-1|AAI09085.1|  448|Homo sapiens CYP24A1 protein protein.
          Length = 448

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 18/59 (30%), Positives = 34/59 (57%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           ++Q K+++E+  +  ++  P   +D   M YL+ CL E++RL P VP   R +++   L
Sbjct: 347 QVQQKLLKEIQSVLPENQVPRA-EDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVL 404


>BC109083-1|AAI09084.1|  448|Homo sapiens CYP24A1 protein protein.
          Length = 448

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 18/59 (30%), Positives = 34/59 (57%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           ++Q K+++E+  +  ++  P   +D   M YL+ CL E++RL P VP   R +++   L
Sbjct: 347 QVQQKLLKEIQSVLPENQVPRA-EDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVL 404


>AM183950-1|CAJ75804.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 41/137 (29%), Positives = 58/137 (42%), Gaps = 4/137 (2%)
 Frame = +3

Query: 255 IQDKVIEELDQIFGD--SDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           IQ ++ EELD   G   S   V ++D   +  L   + E LRL P VP+         T 
Sbjct: 313 IQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHCT---TR 369

Query: 429 PS--NGKKIPAGTTLVIATYKLHRRPDVYQIQTNLTLTTSFRNVPPTDIIMRSCLFQLGP 602
           PS  +G  IP GT ++      H    V++           R + P     R+  F  G 
Sbjct: 370 PSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF---WPDRFLEPGK-NSRALAFGCGA 425

Query: 603 RSCVGRKYAMLKLKVIL 653
           R C+G   A L+L V+L
Sbjct: 426 RVCLGEPLARLELFVVL 442


>AL138805-3|CAM27343.1|  448|Homo sapiens cytochrome P450, family
           24, subfamily A, polypeptide 1 protein.
          Length = 448

 Score = 40.7 bits (91), Expect = 0.005
 Identities = 18/59 (30%), Positives = 34/59 (57%)
 Frame = +3

Query: 252 RIQDKVIEELDQIFGDSDRPVTFQDTLEMKYLERCLMETLRLYPPVPIIARQVNQEITL 428
           ++Q K+++E+  +  ++  P   +D   M YL+ CL E++RL P VP   R +++   L
Sbjct: 347 QVQQKLLKEIQSVLPENQVPRA-EDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVL 404


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 107,156,471
Number of Sequences: 237096
Number of extensions: 2451719
Number of successful extensions: 5232
Number of sequences better than 10.0: 358
Number of HSP's better than 10.0 without gapping: 4495
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4800
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8007229802
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)