Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= prgv0789
(649 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000E49F44 Cluster: PREDICTED: similar to Adaptor pr... 119 7e-26
UniRef50_O95782-2 Cluster: Isoform B of O95782 ; n=19; Bilateria... 114 2e-24
UniRef50_O95782 Cluster: AP-2 complex subunit alpha-1; n=74; Eum... 114 2e-24
UniRef50_Q2PIU2 Cluster: Vesicle coat complex AP-2; n=6; Trichoc... 73 5e-12
UniRef50_Q4PEU6 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_Q9P3H7 Cluster: Related to alpha-adaptin C; n=10; Peziz... 65 1e-09
UniRef50_Q5KEF7 Cluster: Vesicle-mediated transport-related prot... 60 3e-08
UniRef50_Q9C0W7 Cluster: AP-2 complex subunit alpha; n=1; Schizo... 51 3e-05
UniRef50_Q557K4 Cluster: Putative uncharacterized protein; n=3; ... 48 2e-04
UniRef50_Q4T3R5 Cluster: Chromosome undetermined SCAF9936, whole... 47 5e-04
UniRef50_Q9TS61 Cluster: 115 kDa alpha A-adaptin; n=2; Bos tauru... 47 5e-04
UniRef50_Q9FGT0 Cluster: Alpha-adaptin C homolog; n=8; Magnoliop... 34 3.4
UniRef50_UPI0000F1E14C Cluster: PREDICTED: hypothetical protein;... 33 7.9
UniRef50_Q55DP5 Cluster: Putative uncharacterized protein; n=1; ... 33 7.9
UniRef50_Q5RIV7 Cluster: Patched domain-containing protein 1; n=... 33 7.9
>UniRef50_UPI0000E49F44 Cluster: PREDICTED: similar to Adaptor protein
complex AP-2, alpha 2 subunit; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Adaptor protein
complex AP-2, alpha 2 subunit - Strongylocentrotus
purpuratus
Length = 1241
Score = 119 bits (286), Expect = 7e-26
Identities = 54/78 (69%), Positives = 64/78 (82%)
Frame = +1
Query: 10 DLTGTRTKLAGFGMQLLDGIDPNPDNFVCAGIVHTKMQQVGCLMRLEPNKQAQMYRLTIR 189
D RTKL G G+ LLDG+DPNP+NFV AGIVHTK QQVGCLMRLEPN+QA+MYRLT+R
Sbjct: 1164 DTAANRTKLMGTGIGLLDGVDPNPENFVGAGIVHTKTQQVGCLMRLEPNQQARMYRLTLR 1223
Query: 190 SSKESVSQEICNLLADQF 243
+SK VS+ +C+L A QF
Sbjct: 1224 TSKPDVSRVLCDLFATQF 1241
>UniRef50_O95782-2 Cluster: Isoform B of O95782 ; n=19; Bilateria|Rep:
Isoform B of O95782 - Homo sapiens (Human)
Length = 955
Score = 114 bits (274), Expect = 2e-24
Identities = 52/78 (66%), Positives = 61/78 (78%)
Frame = +1
Query: 10 DLTGTRTKLAGFGMQLLDGIDPNPDNFVCAGIVHTKMQQVGCLMRLEPNKQAQMYRLTIR 189
D T+ KL GFG LLD +DPNP+NFV AGI+ TK QVGCL+RLEPN QAQMYRLT+R
Sbjct: 878 DAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLR 937
Query: 190 SSKESVSQEICNLLADQF 243
+SKE VS+ +C LLA QF
Sbjct: 938 TSKEPVSRHLCELLAQQF 955
>UniRef50_O95782 Cluster: AP-2 complex subunit alpha-1; n=74;
Eumetazoa|Rep: AP-2 complex subunit alpha-1 - Homo
sapiens (Human)
Length = 977
Score = 114 bits (274), Expect = 2e-24
Identities = 52/78 (66%), Positives = 61/78 (78%)
Frame = +1
Query: 10 DLTGTRTKLAGFGMQLLDGIDPNPDNFVCAGIVHTKMQQVGCLMRLEPNKQAQMYRLTIR 189
D T+ KL GFG LLD +DPNP+NFV AGI+ TK QVGCL+RLEPN QAQMYRLT+R
Sbjct: 900 DAEVTKAKLLGFGSALLDNVDPNPENFVGAGIIQTKALQVGCLLRLEPNAQAQMYRLTLR 959
Query: 190 SSKESVSQEICNLLADQF 243
+SKE VS+ +C LLA QF
Sbjct: 960 TSKEPVSRHLCELLAQQF 977
>UniRef50_Q2PIU2 Cluster: Vesicle coat complex AP-2; n=6;
Trichocomaceae|Rep: Vesicle coat complex AP-2 -
Aspergillus oryzae
Length = 951
Score = 73.3 bits (172), Expect = 5e-12
Identities = 30/66 (45%), Positives = 45/66 (68%)
Frame = +1
Query: 22 TRTKLAGFGMQLLDGIDPNPDNFVCAGIVHTKMQQVGCLMRLEPNKQAQMYRLTIRSSKE 201
TR + GFG +++D +DPNP N V + H + GCL+RLEPN + MYR+TIR+++E
Sbjct: 853 TRQTVEGFGWRIVDNVDPNPKNIVGCAVFHFGTGKTGCLLRLEPNYEKMMYRITIRATQE 912
Query: 202 SVSQEI 219
+V Q +
Sbjct: 913 AVPQAL 918
>UniRef50_Q4PEU6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 989
Score = 68.9 bits (161), Expect = 1e-10
Identities = 33/75 (44%), Positives = 49/75 (65%), Gaps = 1/75 (1%)
Frame = +1
Query: 10 DLTGTRTKLAGFGMQLLDGIDPNPDNFVCAGIVH-TKMQQVGCLMRLEPNKQAQMYRLTI 186
D+ R L G MQ+L+G+D N N V AG++H +VGCL+RLEPNK A++ RLT+
Sbjct: 904 DVARQRRILEGARMQVLEGVDANATNSVAAGVLHMADAGKVGCLLRLEPNKDAKLARLTV 963
Query: 187 RSSKESVSQEICNLL 231
R++ + S E+ +L
Sbjct: 964 RTTNDLASAEMLRIL 978
>UniRef50_Q9P3H7 Cluster: Related to alpha-adaptin C; n=10;
Pezizomycotina|Rep: Related to alpha-adaptin C -
Neurospora crassa
Length = 988
Score = 65.3 bits (152), Expect = 1e-09
Identities = 34/73 (46%), Positives = 45/73 (61%), Gaps = 1/73 (1%)
Frame = +1
Query: 25 RTKLAGFGMQLLDGIDPNPDNFVCAGIVHTKMQ-QVGCLMRLEPNKQAQMYRLTIRSSKE 201
R L GF LL +DPN NFV A +VHT + GCLMRLEPN QM RLTIR++ E
Sbjct: 886 RQVLEGFRWGLLYNVDPNSKNFVGASVVHTSEGGKFGCLMRLEPNYGTQMVRLTIRATDE 945
Query: 202 SVSQEICNLLADQ 240
+V + ++ ++
Sbjct: 946 TVPPVLLKMMEER 958
>UniRef50_Q5KEF7 Cluster: Vesicle-mediated transport-related protein,
putative; n=2; Filobasidiella neoformans|Rep:
Vesicle-mediated transport-related protein, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 1063
Score = 60.5 bits (140), Expect = 3e-08
Identities = 31/74 (41%), Positives = 47/74 (63%), Gaps = 1/74 (1%)
Frame = +1
Query: 10 DLTGTRTKLAGFGMQLLDGIDPNPDNFVCAGIVH-TKMQQVGCLMRLEPNKQAQMYRLTI 186
D+ + + G + +L ID P+N V AG++H + +VG L R+EPNK A++ RLT+
Sbjct: 977 DIGRNQRVITGNKLSVLPDIDHKPENIVFAGVLHMSSAGKVGILGRVEPNKDAKLCRLTV 1036
Query: 187 RSSKESVSQEICNL 228
RS+ E VS EI +L
Sbjct: 1037 RSTNEHVSAEILSL 1050
>UniRef50_Q9C0W7 Cluster: AP-2 complex subunit alpha; n=1;
Schizosaccharomyces pombe|Rep: AP-2 complex subunit
alpha - Schizosaccharomyces pombe (Fission yeast)
Length = 878
Score = 50.8 bits (116), Expect = 3e-05
Identities = 23/62 (37%), Positives = 37/62 (59%)
Frame = +1
Query: 34 LAGFGMQLLDGIDPNPDNFVCAGIVHTKMQQVGCLMRLEPNKQAQMYRLTIRSSKESVSQ 213
++GF + +D N V AGI+ Q VGCL+R+EPN + + RL+IRS+ S++
Sbjct: 805 VSGFHWGICQNVDSIALNIVGAGIIRFGTQNVGCLLRIEPNYEQNLIRLSIRSTNTSIAN 864
Query: 214 EI 219
+
Sbjct: 865 TL 866
>UniRef50_Q557K4 Cluster: Putative uncharacterized protein; n=3;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum AX4
Length = 989
Score = 48.0 bits (109), Expect = 2e-04
Identities = 26/66 (39%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
Frame = +1
Query: 40 GFGMQLLDGIDPNPDNFV--CAGIVHTKMQQVGCLMRLEPNKQAQMYRLTIRSSKESVSQ 213
G + +L +DPNP+N V C + Q + +R+E N QA M RLTIRS +++
Sbjct: 919 GLNITVLKQVDPNPNNIVASCLFPFGSNGQPINSYIRIETNPQANMCRLTIRSQSATLTN 978
Query: 214 EICNLL 231
I NLL
Sbjct: 979 TIKNLL 984
>UniRef50_Q4T3R5 Cluster: Chromosome undetermined SCAF9936, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF9936,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 276
Score = 46.8 bits (106), Expect = 5e-04
Identities = 23/44 (52%), Positives = 31/44 (70%), Gaps = 1/44 (2%)
Frame = +1
Query: 115 KMQQVGCLMRLE-PNKQAQMYRLTIRSSKESVSQEICNLLADQF 243
+M Q G L + P + QMYRLT+R SK+SVS+ +C LLA+QF
Sbjct: 233 RMPQKGKLAEAKKPPARTQMYRLTLRCSKDSVSKRLCELLAEQF 276
>UniRef50_Q9TS61 Cluster: 115 kDa alpha A-adaptin; n=2; Bos
taurus|Rep: 115 kDa alpha A-adaptin - Bos taurus
(Bovine)
Length = 63
Score = 46.8 bits (106), Expect = 5e-04
Identities = 20/26 (76%), Positives = 23/26 (88%)
Frame = +1
Query: 115 KMQQVGCLMRLEPNKQAQMYRLTIRS 192
K QVGCL+RLEPN QAQMYRLT+R+
Sbjct: 37 KYLQVGCLLRLEPNAQAQMYRLTLRT 62
>UniRef50_Q9FGT0 Cluster: Alpha-adaptin C homolog; n=8;
Magnoliophyta|Rep: Alpha-adaptin C homolog - Arabidopsis
thaliana (Mouse-ear cress)
Length = 1037
Score = 33.9 bits (74), Expect = 3.4
Identities = 20/69 (28%), Positives = 39/69 (56%), Gaps = 3/69 (4%)
Frame = +1
Query: 43 FGMQLLDGIDPNPDNFVCAGIVHTKMQ-QVGCLMRLE--PNKQAQMYRLTIRSSKESVSQ 213
F + + G+DPNP+N V + +++ + CL R+E P + Q+ RLT+ S +++
Sbjct: 927 FHVTICPGLDPNPNNLVASTTFYSETTGAMLCLARIETDPADRTQL-RLTVGSGDPTLTF 985
Query: 214 EICNLLADQ 240
E+ + +Q
Sbjct: 986 ELKEFIKEQ 994
>UniRef50_UPI0000F1E14C Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1207
Score = 32.7 bits (71), Expect = 7.9
Identities = 24/82 (29%), Positives = 46/82 (56%)
Frame = +1
Query: 115 KMQQVGCLMRLEPNKQAQMYRLTIRSSKESVSQEICNLLADQF*KYDRITHKIVDKHLNG 294
++Q++ L+ + P A+ + L++ S+ ES+ E L D+ K + +++K L+
Sbjct: 170 ELQKLALLLSIPP--PAKPHCLSVSSALESIVTEFG--LNDEDLKQRQNILALIEKVLHP 225
Query: 295 VIDA*QFRL*SSYTTKYNFEQS 360
V+ QFRL S +TK+ F+ S
Sbjct: 226 VLPECQFRLYGSSSTKFGFKDS 247
>UniRef50_Q55DP5 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 460
Score = 32.7 bits (71), Expect = 7.9
Identities = 14/40 (35%), Positives = 23/40 (57%)
Frame = -3
Query: 521 RNHYDNKHKPVLISQYESNTNYSELEKYYNKTKINSLLYL 402
+NHY K + L++ + + NY ++E Y NK IN Y+
Sbjct: 79 KNHYGFKDEISLLNYFLTYKNYYDIEDYNNKIYINQTKYI 118
>UniRef50_Q5RIV7 Cluster: Patched domain-containing protein 1; n=33;
Euteleostomi|Rep: Patched domain-containing protein 1 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 897
Score = 32.7 bits (71), Expect = 7.9
Identities = 15/43 (34%), Positives = 22/43 (51%)
Frame = -1
Query: 151 VPVSLNIQLVASLYGQCRHIQSYLD*DRYHLIIACQIQPILFL 23
V V +N V S YG C L+ +RYH + C+I + +L
Sbjct: 414 VAVLVNYFYVFSFYGSCLVFAGQLEQNRYHSVFCCKIPSVEYL 456
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 611,925,235
Number of Sequences: 1657284
Number of extensions: 11662796
Number of successful extensions: 26948
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 25951
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 26929
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48955894634
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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