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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= prgv0589
         (698 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9UJ83 Cluster: 2-hydroxyacyl-CoA lyase 1; n=40; Eukary...   138   2e-31
UniRef50_A6MJX0 Cluster: 2-hydroxyacyl-CoA lyase 1-like protein;...   122   8e-27
UniRef50_Q17474 Cluster: Putative uncharacterized protein; n=3; ...   119   6e-26
UniRef50_A0CTV7 Cluster: Chromosome undetermined scaffold_27, wh...   100   7e-20
UniRef50_Q9FNY6 Cluster: Oxalyl-CoA decarboxylase; n=13; Magnoli...    94   3e-18
UniRef50_Q54DA9 Cluster: Putative uncharacterized protein; n=1; ...    85   2e-15
UniRef50_Q9Y7M1 Cluster: Oxalyl-CoA decarboxylase; n=5; Fungi/Me...    83   6e-15
UniRef50_A7TJH4 Cluster: Putative uncharacterized protein; n=1; ...    79   8e-14
UniRef50_Q75PZ0 Cluster: Oxalyl-CoA decarboxylase; n=1; Bifidoba...    75   2e-12
UniRef50_Q757R7 Cluster: AEL055Cp; n=1; Eremothecium gossypii|Re...    71   2e-11
UniRef50_P39994 Cluster: Uncharacterized protein YEL020C; n=3; S...    71   3e-11
UniRef50_A4VE07 Cluster: 2-hydroxyphytanoyl-CoA lyase, putative;...    68   2e-10
UniRef50_P40149 Cluster: Oxalyl-CoA decarboxylase; n=60; Bacteri...    68   3e-10
UniRef50_Q96F08 Cluster: IlvB (Bacterial acetolactate synthase)-...    64   2e-09
UniRef50_A0LEZ5 Cluster: Thiamine pyrophosphate enzyme TPP bindi...    58   3e-07
UniRef50_Q0TZB1 Cluster: Putative uncharacterized protein; n=1; ...    56   6e-07
UniRef50_Q67QP4 Cluster: Acetolactate synthase-like TPP-requirin...    53   8e-06
UniRef50_UPI0000F347A9 Cluster: UPI0000F347A9 related cluster; n...    52   1e-05
UniRef50_Q54YW0 Cluster: Putative uncharacterized protein; n=3; ...    52   1e-05
UniRef50_Q6DDK5 Cluster: Ilvbl-prov protein; n=2; Bilateria|Rep:...    50   5e-05
UniRef50_P66947 Cluster: Probable acetolactate synthase; n=12; M...    48   2e-04
UniRef50_A2SP25 Cluster: Acetolactate synthase-like TPP-requirin...    48   2e-04
UniRef50_A7H9A1 Cluster: Thiamine pyrophosphate protein central ...    47   4e-04
UniRef50_Q1LF51 Cluster: Thiamine pyrophosphate enzyme-like TPP ...    45   0.002
UniRef50_Q6N658 Cluster: Possible benzaldehyde lyase; n=2; Rhodo...    44   0.004
UniRef50_A1SHD8 Cluster: Thiamine pyrophosphate enzyme domain pr...    44   0.005
UniRef50_A3PYZ1 Cluster: Thiamine pyrophosphate enzyme TPP bindi...    43   0.008
UniRef50_Q2SEE0 Cluster: Thiamine pyrophosphate-requiring enzyme...    42   0.019
UniRef50_Q6D0F1 Cluster: Acetolactate synthase isozyme I large s...    41   0.034
UniRef50_A5K231 Cluster: Bi-functional enzyme: long-chain fatty-...    40   0.044
UniRef50_Q2I6K8 Cluster: IlvB acetolactate synthase; n=1; uncult...    40   0.078
UniRef50_Q64QU8 Cluster: Pyruvate dehydrogenase; n=6; Bacteroide...    38   0.24 
UniRef50_A1SLX3 Cluster: Thiamine pyrophosphate enzyme domain pr...    38   0.31 
UniRef50_Q2AIK5 Cluster: Thiamine pyrophosphate enzyme, C-termin...    37   0.55 
UniRef50_A0BW02 Cluster: Chromosome undetermined scaffold_130, w...    37   0.55 
UniRef50_Q93PS3 Cluster: Sulfoacetaldehyde acetyltransferase; n=...    37   0.55 
UniRef50_Q88U88 Cluster: Pyruvate oxidase; n=5; Lactobacillaceae...    36   0.72 
UniRef50_Q01Q83 Cluster: Thiamine pyrophosphate enzyme domain pr...    36   0.72 
UniRef50_UPI000150A350 Cluster: Thiamine pyrophosphate enzyme, c...    36   1.3  
UniRef50_Q4SYZ1 Cluster: Chromosome 10 SCAF11883, whole genome s...    36   1.3  
UniRef50_Q5LKS2 Cluster: Sulphoacetaldehyde acetyltransferase, p...    36   1.3  
UniRef50_A4ABB6 Cluster: Pyruvate decarboxylase; n=2; Proteobact...    36   1.3  
UniRef50_Q6LF61 Cluster: Putative bi-functional enzyme: long-cha...    36   1.3  
UniRef50_P08142 Cluster: Acetolactate synthase isozyme 1 large s...    36   1.3  
UniRef50_Q6AJI2 Cluster: Acetolactate synthase; n=42; cellular o...    35   1.7  
UniRef50_A0C0T8 Cluster: Chromosome undetermined scaffold_140, w...    35   1.7  
UniRef50_Q5LKG3 Cluster: Acetolactate synthase, large subunit, p...    35   2.2  
UniRef50_Q1ARE6 Cluster: Acetolactate synthase; n=4; Bacteria|Re...    35   2.2  
UniRef50_A1ICC6 Cluster: Putative TPP-requiring enzyme; n=1; Can...    35   2.2  
UniRef50_Q5LQV0 Cluster: Benzaldehyde lyase, putative; n=1; Sili...    34   2.9  
UniRef50_Q2U8M9 Cluster: Thiamine pyrophosphate-requiring enzyme...    34   2.9  
UniRef50_Q18S72 Cluster: Thiamine pyrophosphate enzyme-like TPP ...    34   3.9  
UniRef50_A3VG64 Cluster: Acetolactate synthase large subunit; n=...    34   3.9  
UniRef50_Q8EN64 Cluster: Acetolactate synthase; n=24; cellular o...    33   5.1  
UniRef50_A5US79 Cluster: Thiamine pyrophosphate enzyme, central ...    33   5.1  
UniRef50_A4A7Q3 Cluster: Acetolactate synthase large subunit; n=...    33   5.1  
UniRef50_A0L5Q9 Cluster: Sensor protein; n=1; Magnetococcus sp. ...    33   5.1  
UniRef50_A2BLQ1 Cluster: Putative uncharacterized protein; n=1; ...    33   5.1  
UniRef50_Q9CFJ5 Cluster: 1-deoxyxylulose-5-phosphate synthase; n...    33   6.7  
UniRef50_A3VND4 Cluster: Sensor protein; n=1; Parvularcula bermu...    33   6.7  
UniRef50_Q5CR51 Cluster: DHHC family palmitoyl transferase with ...    33   6.7  
UniRef50_P07003 Cluster: Pyruvate dehydrogenase [cytochrome] (EC...    33   6.7  
UniRef50_Q186C0 Cluster: Acetolactate synthase; n=2; Clostridium...    33   8.9  
UniRef50_A0T1B7 Cluster: Acetohydroxy acid synthase; n=1; uncult...    33   8.9  
UniRef50_A2ESQ8 Cluster: Surface antigen BspA-like; n=3; Trichom...    33   8.9  
UniRef50_P42463 Cluster: Acetolactate synthase large subunit; n=...    33   8.9  
UniRef50_P51853 Cluster: Benzaldehyde lyase; n=3; Pseudomonas fl...    33   8.9  

>UniRef50_Q9UJ83 Cluster: 2-hydroxyacyl-CoA lyase 1; n=40;
           Eukaryota|Rep: 2-hydroxyacyl-CoA lyase 1 - Homo sapiens
           (Human)
          Length = 578

 Score =  138 bits (333), Expect = 2e-31
 Identities = 67/117 (57%), Positives = 83/117 (70%)
 Frame = +1

Query: 241 KSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHR 420
           KS     +  AS  ++P+NYYTVF  VQ+ +P+D  +VSEGANTMDIGR +L N  PRHR
Sbjct: 358 KSNEAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHR 417

Query: 421 LDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           LDAGTFGTMGVG GFAIAAA+  +D +PG     ++     GFSGME+ET+ RY LP
Sbjct: 418 LDAGTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLP 474



 Score = 81.0 bits (191), Expect = 3e-14
 Identities = 35/81 (43%), Positives = 53/81 (65%)
 Frame = +2

Query: 8   ARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERK 187
           AR+NW+LHFG PPRY PDVK IQV+I  EE  N+ K  + +  +I   T+ L++ L +  
Sbjct: 281 ARLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTP 340

Query: 188 FSLQPQNNSWWQGLKQKQKAN 250
           +   P+ + WW+ L++K K+N
Sbjct: 341 WQYPPE-SKWWKTLREKMKSN 360


>UniRef50_A6MJX0 Cluster: 2-hydroxyacyl-CoA lyase 1-like protein;
           n=2; Simiiformes|Rep: 2-hydroxyacyl-CoA lyase 1-like
           protein - Callithrix jacchus (Common marmoset)
          Length = 200

 Score =  122 bits (294), Expect = 8e-27
 Identities = 60/96 (62%), Positives = 70/96 (72%)
 Frame = +1

Query: 304 TVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAM 483
           TVF  VQ+ +P+D  +VSEGANTMDIGR +L N  PRHRLDAGTFGTMGVG GFAIAAAM
Sbjct: 1   TVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHRLDAGTFGTMGVGLGFAIAAAM 60

Query: 484 WCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
             +D  PG     ++     GFSGME+ET+ RY LP
Sbjct: 61  VAKDRHPGQRVICVEGDSAFGFSGMEVETICRYNLP 96


>UniRef50_Q17474 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 634

 Score =  119 bits (287), Expect = 6e-26
 Identities = 57/121 (47%), Positives = 81/121 (66%), Gaps = 2/121 (1%)
 Frame = +1

Query: 235 ETKSKHRF-VEAQASSTAVPLNYYTVFKTVQQGIPK-DSIIVSEGANTMDIGRGLLLNNH 408
           E   K+R  VE      + PLNYY  ++ +++ +   D I+++EGANTMDIGR ++ +  
Sbjct: 412 ENAEKNRAAVEKFVDDHSTPLNYYAAYQPIREFLANNDVIVINEGANTMDIGRTMMPSRL 471

Query: 409 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           P+ RLDAGTFGTMGVG GF++AAA+W RD++P     V++     GFS ME+ET+ RY L
Sbjct: 472 PKRRLDAGTFGTMGVGHGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNL 531

Query: 589 P 591
           P
Sbjct: 532 P 532



 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 31/81 (38%), Positives = 50/81 (61%)
 Frame = +2

Query: 8   ARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERK 187
           AR NW+LHFG PPR+  DVK++Q++I PEEFH + K+E+ +  DI      L  RL +  
Sbjct: 340 ARFNWILHFGLPPRFQKDVKVVQIDICPEEFHQNVKTEVPLLGDIGETLAELTPRLGDWT 399

Query: 188 FSLQPQNNSWWQGLKQKQKAN 250
           +    ++  W++ L++  + N
Sbjct: 400 YD---ESTEWFKKLRENAEKN 417


>UniRef50_A0CTV7 Cluster: Chromosome undetermined scaffold_27, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_27,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 552

 Score = 99.5 bits (237), Expect = 7e-20
 Identities = 48/102 (47%), Positives = 66/102 (64%)
 Frame = +1

Query: 286 VPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGF 465
           +PL YY+ F  ++Q +P+D + V EGANTMD+GR ++ ++ PR +LD+GTFGTMG+G  F
Sbjct: 359 LPLEYYSAFGIIKQYLPRDCVYVGEGANTMDVGRTIIEHDLPRRKLDSGTFGTMGIGLPF 418

Query: 466 AIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           AIA+ +  RD       F +      GFSG E ET  RY LP
Sbjct: 419 AIASKLVFRD----KQVFAILGDSAFGFSGFEFETSTRYNLP 456



 Score = 58.4 bits (135), Expect = 2e-07
 Identities = 29/82 (35%), Positives = 46/82 (56%)
 Frame = +2

Query: 8   ARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERK 187
           AR+NW+LHFG PPR+  + + IQ++  PEEF+N++++   +  D+    + L K     +
Sbjct: 271 ARLNWILHFGLPPRFDDNCQFIQIDNFPEEFNNNRRT-TTLFGDVSLVVDQLQKSFGNWQ 329

Query: 188 FSLQPQNNSWWQGLKQKQKANT 253
           FS    N  W   L  K+  NT
Sbjct: 330 FS----NKQWIDKLFDKRNKNT 347


>UniRef50_Q9FNY6 Cluster: Oxalyl-CoA decarboxylase; n=13;
           Magnoliophyta|Rep: Oxalyl-CoA decarboxylase -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 572

 Score = 93.9 bits (223), Expect = 3e-18
 Identities = 51/128 (39%), Positives = 72/128 (56%), Gaps = 4/128 (3%)
 Frame = +1

Query: 217 VAGTETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGI----PKDSIIVSEGANTMDIG 384
           V     + K     +E Q +   VP N+ T  + ++  I        ++VSEGANTMD+G
Sbjct: 352 VESISKKAKENGEKMEIQLAKDVVPFNFLTPMRIIRDAILAVEGPSPVVVSEGANTMDVG 411

Query: 385 RGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEI 564
           R +L+   PR RLDAGT+GTMGVG G+ IAAA+     +P  +   ++     GFS ME+
Sbjct: 412 RSVLVQKEPRTRLDAGTWGTMGVGLGYCIAAAV----ASPDRLVVAVEGDSGFGFSAMEV 467

Query: 565 ETMFRYKL 588
           ET+ RY L
Sbjct: 468 ETLVRYNL 475



 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 29/81 (35%), Positives = 47/81 (58%)
 Frame = +2

Query: 8   ARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERK 187
           AR+NW+LHFG+ P++  DVK I V++S EE    +K  L +  D +     L + + +  
Sbjct: 284 ARLNWLLHFGESPKWDKDVKFILVDVSEEEI-ELRKPHLGIVGDAKTVIGLLNREIKDDP 342

Query: 188 FSLQPQNNSWWQGLKQKQKAN 250
           F L  ++NSW + + +K K N
Sbjct: 343 FCL-GKSNSWVESISKKAKEN 362


>UniRef50_Q54DA9 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 580

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 50/123 (40%), Positives = 69/123 (56%), Gaps = 2/123 (1%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQG--IPKDSIIVSEGANTMDIGRGLLLN 402
           + +TKS    +    ++    L Y+ VF  ++ G    +D+I V+EGANTMDIGR  +  
Sbjct: 364 QVKTKSLATLMSEPQNNDQEYLTYHKVFNALRVGGLFQEDTIFVNEGANTMDIGRLCIPQ 423

Query: 403 NHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRY 582
             PR RLDAGT  TMGVG G+++AA + C    P      ++     GFS ME+E   RY
Sbjct: 424 TLPRSRLDAGTLATMGVGVGYSVAAQI-C---FPDRSVVCIQGDSAFGFSAMEMEVAVRY 479

Query: 583 KLP 591
           KLP
Sbjct: 480 KLP 482



 Score = 42.7 bits (96), Expect = 0.008
 Identities = 30/100 (30%), Positives = 47/100 (47%), Gaps = 16/100 (16%)
 Frame = +2

Query: 2   LQARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKK----SELAVHSDIRPFTEALVK 169
           L AR+NWM +FG+ P ++ DVK I V++   +   +K      E+A+  D R  + A ++
Sbjct: 269 LGARLNWMFNFGKAPTFSTDVKFIIVDVDENQASKTKNPNVVPEIAIVGDAR-LSIAEMR 327

Query: 170 RLSERKFSLQPQ------------NNSWWQGLKQKQKANT 253
           +L   +   QPQ              SWW  L Q  +  T
Sbjct: 328 KLFIGETDEQPQPPQDSLIKSMKMEESWWSNLNQDIQVKT 367


>UniRef50_Q9Y7M1 Cluster: Oxalyl-CoA decarboxylase; n=5;
           Fungi/Metazoa group|Rep: Oxalyl-CoA decarboxylase -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 568

 Score = 83.0 bits (196), Expect = 6e-15
 Identities = 56/126 (44%), Positives = 74/126 (58%), Gaps = 6/126 (4%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVPLNY--YTVFKTVQQGIPKDS---IIVSEGANTMDIGRGL 393
           ET +K++ + +E++ SS  + +NY  Y V + +Q    K       VSEGANTMD GR L
Sbjct: 345 ETRSKNEKKALESRKSSIPLQMNYALYVVNEELQSLSLKSKRNITWVSEGANTMDRGRQL 404

Query: 394 LLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKE-TLLLGFSGMEIET 570
           L   HPR RLDAGT  TMGVG G+AIA+A     +A  +   V+ E     GFS ME+ET
Sbjct: 405 LEVTHPRGRLDAGTMSTMGVGMGYAIASA-----FAHSSDKIVVVEGDSAFGFSAMELET 459

Query: 571 MFRYKL 588
             R +L
Sbjct: 460 AIRNQL 465



 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 20/64 (31%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
 Frame = +2

Query: 8   ARMNWMLHFGQPPRYAPDVKIIQVEISPEEF-HNSKKSELAVHSDIRPFTEALVKRLSER 184
           AR+NW+  +G PP+++P+ K IQ++ + E   +N+   +LA+ +D+    + L K +   
Sbjct: 270 ARLNWIFQYGLPPKWSPNAKFIQIDTNAETLGNNAADLDLAIWADVGLTIDCLFKLVQTW 329

Query: 185 KFSL 196
           K+S+
Sbjct: 330 KYSV 333


>UniRef50_A7TJH4 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 571

 Score = 79.4 bits (187), Expect = 8e-14
 Identities = 44/108 (40%), Positives = 66/108 (61%), Gaps = 1/108 (0%)
 Frame = +1

Query: 268 QASSTAVPLNYYTVFKTVQQGI-PKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGT 444
           +++ +   LNY  V+ ++++ +  +++IIV EGANTMDI R     ++P+HRLD G   T
Sbjct: 368 ESNHSTSQLNYNEVYGSLRKILNDRETIIVMEGANTMDIARISFKTDYPQHRLDCGNLAT 427

Query: 445 MGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           MGVG G+AI+A +      P     +++     GFSGMEIET  R KL
Sbjct: 428 MGVGLGYAISAKL----SRPDKTVVLIQGDSAFGFSGMEIETAVRNKL 471



 Score = 36.7 bits (81), Expect = 0.55
 Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
 Frame = +2

Query: 11  RMNWMLHFGQPPRYAPDVKIIQVEISPEE--FHNSKKSELAVHSDIRPFTEALVKRLSER 184
           ++NW+LHFG   ++  +   IQ++ SP     +NSK  E ++  +I    + L + L + 
Sbjct: 279 KLNWILHFGSSSKWNENTLFIQIDNSPSNLGLNNSKGLEYSLFGNISVTLDKLSRSLIKF 338

Query: 185 KFSLQPQNNSWWQGLKQKQKAN 250
             + Q +     + +K K K N
Sbjct: 339 NKNKQWRYQGPTENIKIKIKEN 360


>UniRef50_Q75PZ0 Cluster: Oxalyl-CoA decarboxylase; n=1;
           Bifidobacterium animalis|Rep: Oxalyl-CoA decarboxylase -
           Bifidobacterium animalis subsp. lactis (Bifidobacterium
           lactis)
          Length = 590

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 42/111 (37%), Positives = 60/111 (54%), Gaps = 2/111 (1%)
 Frame = +1

Query: 265 AQASSTAVPLNYYTVFKTVQQGIP--KDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTF 438
           A+ +S  VP+ +Y     +++     KD I+ +EGANT+D  R ++    PRHRLD GT+
Sbjct: 370 ARVNSNTVPMGHYDALGAIKKVYDQHKDMILTNEGANTLDDCRNIIDIYQPRHRLDCGTW 429

Query: 439 GTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           G MG   G++I AA+     A G     +      GF GME+E   RY LP
Sbjct: 430 GVMGCAVGYSIGAAV-----ATGKPVLYVGGDSGFGFDGMEVEVACRYNLP 475



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 26/81 (32%), Positives = 40/81 (49%)
 Frame = +2

Query: 8   ARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERK 187
           AR+NWML+FG+   + P+VK IQ++I P E  N++     V  DI+   + +   L +  
Sbjct: 287 ARLNWMLNFGEGKEWNPNVKFIQIDIDPNEIENARSIACPVVGDIKSAMQMINAGLEKTP 346

Query: 188 FSLQPQNNSWWQGLKQKQKAN 250
                Q   W   LK   + N
Sbjct: 347 VKASAQ---WLDMLKADAEKN 364


>UniRef50_Q757R7 Cluster: AEL055Cp; n=1; Eremothecium gossypii|Rep:
           AEL055Cp - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 545

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 41/101 (40%), Positives = 61/101 (60%), Gaps = 1/101 (0%)
 Frame = +1

Query: 289 PLNYYTVFKTVQQGIP-KDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGF 465
           PLNY+ V+  +++ I  K++I+ +EGANTMD  R     ++P+ RLDAGT  TMG+G G+
Sbjct: 355 PLNYHAVYSLLRKLIDDKNTILSAEGANTMDNSRLWFGTDYPKRRLDAGTGATMGLGVGY 414

Query: 466 AIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           A++A +      P      L+     GFS ME+ET  R K+
Sbjct: 415 ALSAKL----ANPDKFVVALEGDSAFGFSCMELETAVRNKV 451



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 22/62 (35%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
 Frame = +2

Query: 2   LQARMNWMLHFGQPPRYAPDVKIIQVEISPEEF--HNSKKSELAVHSDIRPFTEALVKRL 175
           L AR+NW+LH+G  P++  D   IQV+  P     +NS     +V SD+  F  A+   L
Sbjct: 261 LGARLNWILHYGSAPKWNADATFIQVDRDPATLGHNNSSGVNYSVLSDVELFINAITAVL 320

Query: 176 SE 181
            +
Sbjct: 321 PQ 322


>UniRef50_P39994 Cluster: Uncharacterized protein YEL020C; n=3;
           Saccharomycetales|Rep: Uncharacterized protein YEL020C -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 560

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 44/100 (44%), Positives = 59/100 (59%), Gaps = 1/100 (1%)
 Frame = +1

Query: 292 LNYYTVFKTVQQGIPK-DSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFA 468
           LNY  V+ T++  I    +I+V+EGANTMDI R     + PR RLDAGT  TMG+G G+A
Sbjct: 369 LNYNQVYGTLRPLIDDYRTILVTEGANTMDIARISFPTDAPRRRLDAGTNATMGIGLGYA 428

Query: 469 IAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           +A    C+   P     +++     GFS MEIET  R +L
Sbjct: 429 LA----CKASHPELDVVLIQGDSAFGFSAMEIETAVRCQL 464



 Score = 43.2 bits (97), Expect = 0.006
 Identities = 28/90 (31%), Positives = 48/90 (53%), Gaps = 4/90 (4%)
 Frame = +2

Query: 2   LQARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKS---ELAVHSDIRPFTEALVKR 172
           L AR+NW+LHFG  P++  +   IQ + +PE   ++  S   +L++  DI     ALV+ 
Sbjct: 271 LGARLNWILHFGTSPKWNSESIFIQFDSNPETLGDNNVSPGADLSIWGDIGLSVTALVEE 330

Query: 173 LSERKFSLQPQNNSW-WQGLKQKQKANTDL 259
           L+        Q++ W + G+KQ+ +    L
Sbjct: 331 LTR-------QDSCWKYSGVKQEIREKIQL 353


>UniRef50_A4VE07 Cluster: 2-hydroxyphytanoyl-CoA lyase, putative;
           n=1; Tetrahymena thermophila SB210|Rep:
           2-hydroxyphytanoyl-CoA lyase, putative - Tetrahymena
           thermophila SB210
          Length = 405

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 33/67 (49%), Positives = 45/67 (67%)
 Frame = +2

Query: 8   ARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERK 187
           AR+NW+LHFG+PPR+  +VKII +EI PEEF  + K  + +  DI   T+ LV+ L  R 
Sbjct: 268 ARLNWILHFGEPPRFNKNVKIIHIEICPEEFDTNVKGSVNLFGDIGLITKQLVQELQGR- 326

Query: 188 FSLQPQN 208
           +SL  QN
Sbjct: 327 YSLFLQN 333


>UniRef50_P40149 Cluster: Oxalyl-CoA decarboxylase; n=60;
           Bacteria|Rep: Oxalyl-CoA decarboxylase - Oxalobacter
           formigenes
          Length = 568

 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 36/84 (42%), Positives = 50/84 (59%)
 Frame = +1

Query: 340 DSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSF 519
           D  +V+EGAN +D  R ++    PR RLD+GT+G MG+G G+ +AAA        G    
Sbjct: 393 DISLVNEGANALDNTRMIVDMLKPRKRLDSGTWGVMGIGMGYCVAAAA-----VTGKPVI 447

Query: 520 VLKETLLLGFSGMEIETMFRYKLP 591
            ++     GFSGME+ET+ RY LP
Sbjct: 448 AVEGDSAFGFSGMELETICRYNLP 471


>UniRef50_Q96F08 Cluster: IlvB (Bacterial acetolactate
           synthase)-like; n=36; cellular organisms|Rep: IlvB
           (Bacterial acetolactate synthase)-like - Homo sapiens
           (Human)
          Length = 632

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 40/121 (33%), Positives = 62/121 (51%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 408
           E + + +  F E  A   A  LN   V + V++ +P +SI+V +G + +     L+    
Sbjct: 424 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 483

Query: 409 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           P   LD G FGT+GVG GFA+ A + CR   P    + L      G+S +E +T  R+K+
Sbjct: 484 PLRWLDPGAFGTLGVGAGFALGAKL-CR---PDAEVWCLFGDGAFGYSLIEFDTFVRHKI 539

Query: 589 P 591
           P
Sbjct: 540 P 540


>UniRef50_A0LEZ5 Cluster: Thiamine pyrophosphate enzyme TPP binding
           domain protein; n=1; Syntrophobacter fumaroxidans
           MPOB|Rep: Thiamine pyrophosphate enzyme TPP binding
           domain protein - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 568

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 33/106 (31%), Positives = 55/106 (51%)
 Frame = +1

Query: 274 SSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGV 453
           SS AVP++   + + +   +  DSI++++G +T+ +   ++    P   LD G  GT+GV
Sbjct: 373 SSDAVPIHPLRLAREIDAFLRDDSILIADGGDTVTMSASVIRPRGPGQWLDPGPLGTLGV 432

Query: 454 GPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           G  FAIAA    +   P     VL      G +G + +T+ R+ LP
Sbjct: 433 GTPFAIAA----KAAMPARDVVVLFGDGAFGLTGFDYDTLIRFNLP 474


>UniRef50_Q0TZB1 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 478

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 8/90 (8%)
 Frame = +1

Query: 235 ETKSKH-RFVEAQASSTAVPLNY---YTVFKTVQQGIPKDS----IIVSEGANTMDIGRG 390
           + K K+ +     A   ++PL Y   + V KT    + + S      ++E  NTMDI R 
Sbjct: 232 QAKEKNEKIASLTAQGPSMPLKYARAFDVMKTTLHNLSQPSEGRICYMAESTNTMDISRS 291

Query: 391 LLLNNHPRHRLDAGTFGTMGVGPGFAIAAA 480
           +    HPR RLDAGT+ TMG G  +AIAA+
Sbjct: 292 IFPLEHPRLRLDAGTYATMGFGLPYAIAAS 321



 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 1/84 (1%)
 Frame = +2

Query: 2   LQARMNWMLHFGQPPRYAPDVKIIQVEISPEEF-HNSKKSELAVHSDIRPFTEALVKRLS 178
           L AR+NW+ H G+ P++ P+ K IQV+IS EE   NS+ +E ++  D+      L+  L 
Sbjct: 156 LGARLNWIFHHGEAPKWNPEAKFIQVDISAEETGRNSESAEHSLLGDVGVVATQLLTWLG 215

Query: 179 ERKFSLQPQNNSWWQGLKQKQKAN 250
           +  F L   ++ +   ++Q ++ N
Sbjct: 216 DWTFDL--NSSEYMAKIRQAKEKN 237


>UniRef50_Q67QP4 Cluster: Acetolactate synthase-like TPP-requiring
           enzyme; n=1; Symbiobacterium thermophilum|Rep:
           Acetolactate synthase-like TPP-requiring enzyme -
           Symbiobacterium thermophilum
          Length = 551

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 32/122 (26%), Positives = 63/122 (51%), Gaps = 1/122 (0%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLL-LNN 405
           E E + +   ++   +S A+P+N   +   + + +P+D+I++ +G + +     ++ +  
Sbjct: 345 EAEEEKRLARMQPDLTSEAMPVNPLRLCAEIDRALPEDAILIGDGGDFVATAANVVRVRR 404

Query: 406 HPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYK 585
           +P   +D G  GT+G+G GFA+AA +   D     V  +L +    G + ME+E   R  
Sbjct: 405 YPAGWMDPGPLGTLGIGMGFAMAARLAHPDVP---VVLLLGDG-TAGLNLMEVEAAVRQN 460

Query: 586 LP 591
           LP
Sbjct: 461 LP 462


>UniRef50_UPI0000F347A9 Cluster: UPI0000F347A9 related cluster; n=1;
           Bos taurus|Rep: UPI0000F347A9 UniRef100 entry - Bos
           Taurus
          Length = 442

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 38/121 (31%), Positives = 58/121 (47%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 408
           + + + +  F E      A  LN   V + V+  +P + I+V +G N +     L+    
Sbjct: 319 QADQQKEQTFREKALMPVAQHLNPVRVLQLVEDTLPDNPILV-DGGNFVGTAAYLVQPRG 377

Query: 409 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           P   LD G FGT+GVG GFA+ A + CR  A     + L      G+S  E +T  R+K+
Sbjct: 378 PLCWLDPGAFGTLGVGAGFALGAKL-CRLDAE---VWCLFGDGAFGYSLFEFDTFVRHKI 433

Query: 589 P 591
           P
Sbjct: 434 P 434


>UniRef50_Q54YW0 Cluster: Putative uncharacterized protein; n=3;
            Eukaryota|Rep: Putative uncharacterized protein -
            Dictyostelium discoideum AX4
          Length = 904

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 31/99 (31%), Positives = 53/99 (53%)
 Frame = +1

Query: 292  LNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAI 471
            LN     +   + +P  +I+V++G + +     ++    P   LD G FGT+GVG GF+I
Sbjct: 718  LNPLKALQMFDEQLPHKTIMVADGGDFVGSASYIVRPRAPLSWLDPGVFGTLGVGAGFSI 777

Query: 472  AAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
            AA + CR   P +  + +      G+S  E++TM R+K+
Sbjct: 778  AAKL-CR---PDHQVWTIYGDGAFGYSIPELDTMVRHKI 812


>UniRef50_Q6DDK5 Cluster: Ilvbl-prov protein; n=2; Bilateria|Rep:
           Ilvbl-prov protein - Xenopus laevis (African clawed
           frog)
          Length = 649

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 41/126 (32%), Positives = 62/126 (49%), Gaps = 5/126 (3%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVP---LNYYTVFKTVQQG--IPKDSIIVSEGANTMDIGRGL 393
           E   +  HR  E + SS   P   +N  +V   ++      ++SIIV++G + +     +
Sbjct: 423 ELLAREHHRDEEIRQSSLTQPAERINPLSVLWQLEHNGLTDQESIIVADGGDFVGSAAYI 482

Query: 394 LLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETM 573
           L    P   LD G FGT+GVG GFA+ A + CR   P    +V+      G+S  E +TM
Sbjct: 483 LRPRGPLSWLDPGPFGTLGVGGGFALGAKL-CR---PQAHVWVVYGDGSAGYSLAEWDTM 538

Query: 574 FRYKLP 591
            R+K P
Sbjct: 539 ARHKAP 544


>UniRef50_P66947 Cluster: Probable acetolactate synthase; n=12;
           Mycobacterium|Rep: Probable acetolactate synthase -
           Mycobacterium bovis
          Length = 547

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 29/109 (26%), Positives = 56/109 (51%)
 Frame = +1

Query: 262 EAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFG 441
           +A+     +PL+   V+  +   + +D+++V +  +       ++ +  P   LD+G FG
Sbjct: 353 KAELVDDRIPLHPMRVYAELAALLERDALVVIDAGDFGSYAGRMIDSYLPGCWLDSGPFG 412

Query: 442 TMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
            +G GPG+A+AA +      P     +L+     GFSGME +T+ R+ +
Sbjct: 413 CLGSGPGYALAAKL----ARPQRQVVLLQGDGAFGFSGMEWDTLVRHNV 457


>UniRef50_A2SP25 Cluster: Acetolactate synthase-like TPP-requiring
           enzyme; n=3; Proteobacteria|Rep: Acetolactate
           synthase-like TPP-requiring enzyme - Methylibium
           petroleiphilum (strain PM1)
          Length = 586

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 31/92 (33%), Positives = 47/92 (51%), Gaps = 1/92 (1%)
 Frame = +1

Query: 319 VQQGIPKDSIIVSEGANTMDIGR-GLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRD 495
           VQ+ I  D+++V++G + +   R G+    +    LD G  G +GVG  F I AA+ C  
Sbjct: 382 VQRAIGDDAVVVADGGDFLAFARVGIRCGTY----LDPGPLGCIGVGTSFGIGAALAC-- 435

Query: 496 YAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
             P     VL      GF+ MEI+T  R+ +P
Sbjct: 436 --PQRTVAVLTGDGAFGFNAMEIDTAVRHGVP 465


>UniRef50_A7H9A1 Cluster: Thiamine pyrophosphate protein central
           region; n=1; Anaeromyxobacter sp. Fw109-5|Rep: Thiamine
           pyrophosphate protein central region - Anaeromyxobacter
           sp. Fw109-5
          Length = 550

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 36/123 (29%), Positives = 54/123 (43%), Gaps = 2/123 (1%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPK--DSIIVSEGANTMDIGRGLLLN 402
           ET    K R  E    S   P++++ + K +     +  D   V +G N + +   +L  
Sbjct: 343 ETSRAEKQRGYE---ESDQRPIHHFRLAKALDTVASRAGDVTFVGDGGNVVAVAAKVLKV 399

Query: 403 NHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRY 582
             P   LD G  G +GVG  FAIAA +     AP     V++     G +G + ET  R+
Sbjct: 400 KKPGRWLDPGPLGCLGVGAPFAIAAKL----LAPERPVCVIQGDGAFGLNGFDFETAVRF 455

Query: 583 KLP 591
            LP
Sbjct: 456 GLP 458



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 17/81 (20%), Positives = 39/81 (48%)
 Frame = +2

Query: 14  MNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERKFS 193
           +++ + +G  P +AP  +++QV++   E   ++  ++ +  D R   E L     E    
Sbjct: 273 LDFRVGYGTEPTFAPGARVVQVDVDGAEIGRNRPIDVGIVGDARSVLEQL-----EAGAR 327

Query: 194 LQPQNNSWWQGLKQKQKANTD 256
           L P   +W   L+Q++ +  +
Sbjct: 328 LAPAAEAWRAFLRQQETSRAE 348


>UniRef50_Q1LF51 Cluster: Thiamine pyrophosphate enzyme-like TPP
           binding region; n=3; Bacteria|Rep: Thiamine
           pyrophosphate enzyme-like TPP binding region - Ralstonia
           metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
          Length = 640

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 30/122 (24%), Positives = 54/122 (44%)
 Frame = +1

Query: 226 TETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNN 405
           TE E  +  + +    S    P++ Y V   + + +  ++I + +G + + I    +   
Sbjct: 426 TEAEAVATEKLMPLFKSENK-PIHPYRVAYELNEFLADNTIYIGDGGDVVTISAQAVRPR 484

Query: 406 HPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYK 585
            P   +D G  G++GVG GFAIAA +      PG            G +  ++ET  R+ 
Sbjct: 485 RPGQWMDPGALGSLGVGTGFAIAAGV----ANPGKEVLCYYGDGSFGMTAFDMETANRFG 540

Query: 586 LP 591
           +P
Sbjct: 541 VP 542


>UniRef50_Q6N658 Cluster: Possible benzaldehyde lyase; n=2;
           Rhodopseudomonas palustris|Rep: Possible benzaldehyde
           lyase - Rhodopseudomonas palustris
          Length = 600

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 29/97 (29%), Positives = 42/97 (43%)
 Frame = +1

Query: 301 YTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAA 480
           Y   + V      ++  V +G      G    + + P   L  G  G +G+GPGFAI A 
Sbjct: 395 YHAARAVADAAGTEAAYVFDGGEAASWGAAAAVVDRPGALLGHGYLGCLGIGPGFAIGAQ 454

Query: 481 MWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           +     AP      L     LGF   E++TM R++LP
Sbjct: 455 L----AAPERRVIHLTGDGALGFHLQELDTMVRHRLP 487


>UniRef50_A1SHD8 Cluster: Thiamine pyrophosphate enzyme domain
           protein TPP-binding; n=4; Actinomycetales|Rep: Thiamine
           pyrophosphate enzyme domain protein TPP-binding -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 551

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 28/109 (25%), Positives = 52/109 (47%)
 Frame = +1

Query: 265 AQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGT 444
           A   + A P++   ++  +   + +D++++ +G + +      +    P   LD G +G 
Sbjct: 358 ALLGAEADPIHPARIYGDLVPRLAEDAVVIGDGGDFVSFAGKFVEPKRPGGWLDPGPYGC 417

Query: 445 MGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           +G G G AIAA    R   P     +L      GFS M+++T+ R+ LP
Sbjct: 418 LGAGLGAAIAA----RLARPSAQVVLLLGDGAAGFSLMDVDTLVRHHLP 462


>UniRef50_A3PYZ1 Cluster: Thiamine pyrophosphate enzyme TPP binding
           domain protein; n=3; Mycobacterium|Rep: Thiamine
           pyrophosphate enzyme TPP binding domain protein -
           Mycobacterium sp. (strain JLS)
          Length = 588

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 35/122 (28%), Positives = 53/122 (43%)
 Frame = +1

Query: 226 TETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNN 405
           T  + +  HR +   A++ +  ++ Y   + V +  P  +  V +GA             
Sbjct: 362 TAVQAQRFHRALYPDAATPSGRMHPYFAARAVVEACPPGTTFVLDGAEAPAWAEFFATTE 421

Query: 406 HPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYK 585
                L  G  GT+GVGPGFAI AA   R  AP  V  +  +    GF   E +TM R+ 
Sbjct: 422 TVGGVLRLGYLGTLGVGPGFAIGAAR-ARPAAP--VVLITGDG-AAGFHLGEFDTMARHG 477

Query: 586 LP 591
           +P
Sbjct: 478 MP 479


>UniRef50_Q2SEE0 Cluster: Thiamine pyrophosphate-requiring enzyme;
           n=3; Proteobacteria|Rep: Thiamine
           pyrophosphate-requiring enzyme - Hahella chejuensis
           (strain KCTC 2396)
          Length = 591

 Score = 41.5 bits (93), Expect = 0.019
 Identities = 21/80 (26%), Positives = 38/80 (47%)
 Frame = +1

Query: 241 KSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHR 420
           + + + +  QA +    +N   +   +   + + S I+++G + +      L    P   
Sbjct: 389 RQREKDIRTQALTEGGRINPLDLLLQIDTALDEKSAIIADGGDFVATAAYTLRPRSPLSW 448

Query: 421 LDAGTFGTMGVGPGFAIAAA 480
           LD G FGT+GVG GF + AA
Sbjct: 449 LDPGVFGTLGVGGGFVLGAA 468


>UniRef50_Q6D0F1 Cluster: Acetolactate synthase isozyme I large
           subunit; n=5; Bacteria|Rep: Acetolactate synthase
           isozyme I large subunit - Erwinia carotovora subsp.
           atroseptica (Pectobacterium atrosepticum)
          Length = 554

 Score = 40.7 bits (91), Expect = 0.034
 Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
 Frame = +1

Query: 289 PLNYYTVFKTVQQGIPKDSIIVSE-GANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGF 465
           PL++Y + +   Q +  D+II ++ G + M + +   L   PR  L +G FGTMG G   
Sbjct: 359 PLSHYGLVQATAQALTDDAIITTDVGQHQMWVAQSYPLRR-PRQWLTSGGFGTMGFGLPA 417

Query: 466 AIAAAM 483
           AI AA+
Sbjct: 418 AIGAAL 423


>UniRef50_A5K231 Cluster: Bi-functional enzyme: long-chain fatty-acid
            Co-A ligase and oxalyl Co- A decarboxylase, putative;
            n=1; Plasmodium vivax|Rep: Bi-functional enzyme:
            long-chain fatty-acid Co-A ligase and oxalyl Co- A
            decarboxylase, putative - Plasmodium vivax
          Length = 1314

 Score = 40.3 bits (90), Expect = 0.044
 Identities = 30/92 (32%), Positives = 45/92 (48%)
 Frame = +1

Query: 313  KTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCR 492
            K + Q I K  +I +EG+ T+ +G   L    P + +     G MGV    AI  A+  R
Sbjct: 1121 KFLNQEIKKRVVITNEGSITLHLGILFLPQLGPYNFVIPQINGMMGVSMNAAICGALNDR 1180

Query: 493  DYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
            +    NV F +      GF+  E+ET+ R+KL
Sbjct: 1181 E----NVVFAILGDSSFGFTSNEVETICRFKL 1208


>UniRef50_Q2I6K8 Cluster: IlvB acetolactate synthase; n=1;
           uncultured delta proteobacterium DeepAnt-32C6|Rep: IlvB
           acetolactate synthase - uncultured delta proteobacterium
           DeepAnt-32C6
          Length = 680

 Score = 39.5 bits (88), Expect = 0.078
 Identities = 35/120 (29%), Positives = 56/120 (46%), Gaps = 2/120 (1%)
 Frame = +1

Query: 238 TKSKHRFVEAQAS-STAVPLNYYTVFKTVQQGIPKDSIIVSE-GANTMDIGRGLLLNNHP 411
           T+   R++ A+   S AVPL        +QQ +P D+I+ S+ G + +   + L +    
Sbjct: 469 TQESTRYLNAELRVSDAVPLTPQRWRADLQQVLPADAIVFSDIGGHMLFNIQHLCIGREQ 528

Query: 412 RHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           R  L+ G FG+MG G   A+ AA+     AP      +        +GME+ T   Y +P
Sbjct: 529 RFMLNLG-FGSMGHGTSAAVGAAL----AAPERPVVSIIGDACFTMNGMELLTAREYGVP 583


>UniRef50_Q64QU8 Cluster: Pyruvate dehydrogenase; n=6;
           Bacteroidetes|Rep: Pyruvate dehydrogenase - Bacteroides
           fragilis
          Length = 579

 Score = 37.9 bits (84), Expect = 0.24
 Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
 Frame = +2

Query: 59  DVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERK-FSLQPQNNSWWQGLKQ 235
           D+KI+QV+I PE      K +L +  D+R    AL+  L ++K  S   +    ++G+K+
Sbjct: 285 DIKIVQVDIKPERLGRRAKVDLGLCGDVRSTLRALLPMLQQKKNDSFLRKQLKRYEGVKK 344

Query: 236 KQKANTD 256
              A T+
Sbjct: 345 DLAAYTE 351


>UniRef50_A1SLX3 Cluster: Thiamine pyrophosphate enzyme domain
           protein TPP-binding; n=2; Bacteria|Rep: Thiamine
           pyrophosphate enzyme domain protein TPP-binding -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 588

 Score = 37.5 bits (83), Expect = 0.31
 Identities = 33/109 (30%), Positives = 47/109 (43%)
 Frame = +1

Query: 265 AQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGT 444
           A+A     P++   V    QQ +P D++ V +G NT+         + PR  L    FG 
Sbjct: 368 AKAVKPGSPVHPGHVPSVAQQVMPDDTVWVFDGGNTVVWSNFHHSADVPRTILSTYKFGM 427

Query: 445 MGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           +G G G A+ AA+     AP     VL      G    E+E+  R  LP
Sbjct: 428 LGAGMGQALGAAV----AAPDQRVCVLIGDGAFGMHPTEVESAVRLGLP 472


>UniRef50_Q2AIK5 Cluster: Thiamine pyrophosphate enzyme, C-terminal
           TPP-binding:Thiamine pyrophosphate enzyme, central
           region:Thiamine pyrophosphate enzyme, N- terminal TPP
           binding region; n=1; Halothermothrix orenii H 168|Rep:
           Thiamine pyrophosphate enzyme, C-terminal
           TPP-binding:Thiamine pyrophosphate enzyme, central
           region:Thiamine pyrophosphate enzyme, N- terminal TPP
           binding region - Halothermothrix orenii H 168
          Length = 534

 Score = 36.7 bits (81), Expect = 0.55
 Identities = 33/107 (30%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
 Frame = +1

Query: 289 PLNYYTVFKTVQQGIPKDSII-VSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGF 465
           PL   T+ + + +    D II +  G N +  GR     N   H L +GT+ TM    GF
Sbjct: 354 PLPPQTIIRIISENTQPDEIICLDSGDNVIWFGR--YFGNKCAHTLISGTWRTM----GF 407

Query: 466 AIAAAMWCRDYAPGNVSFVLKETLLLGFSGM-----EIETMFRYKLP 591
           ++ +A+  R   P N     + T ++G  G+     EI T  RY LP
Sbjct: 408 SLPSALAARINKPNN-----QVTSIIGDGGLSMVLAEISTAVRYNLP 449


>UniRef50_A0BW02 Cluster: Chromosome undetermined scaffold_130,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_130,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 298

 Score = 36.7 bits (81), Expect = 0.55
 Identities = 22/74 (29%), Positives = 39/74 (52%), Gaps = 1/74 (1%)
 Frame = +2

Query: 62  VKIIQVE-ISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERKFSLQPQNNSWWQGLKQK 238
           +K+I ++  S  EF N K ++    +++RPF E L++R  +    LQ      ++   Q 
Sbjct: 22  MKVIPIKPTSQSEFQNKKSADHLDPNELRPFLEDLMRRYDKMALELQAAQAKNYEYNDQN 81

Query: 239 QKANTDL*RLKQAA 280
           QK   +  +LK+AA
Sbjct: 82  QKLIRENDQLKEAA 95


>UniRef50_Q93PS3 Cluster: Sulfoacetaldehyde acetyltransferase; n=5;
           Peptococcaceae|Rep: Sulfoacetaldehyde acetyltransferase
           - Desulfonispora thiosulfatigenes
          Length = 584

 Score = 36.7 bits (81), Expect = 0.55
 Identities = 29/111 (26%), Positives = 45/111 (40%)
 Frame = +1

Query: 259 VEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTF 438
           +E  A     P+N   V   V + +P+D+I+ ++  N             P+  + A TF
Sbjct: 363 IEEMAMMPGNPINPRRVLFEVAKLMPEDAILTTDIGNVASTANSYFKFTKPKKHIAALTF 422

Query: 439 GTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           G      GFA  A +  +   P +    +      G S  EI T  +YKLP
Sbjct: 423 G----NTGFAYQAGLGAQMAEPDSPVVAIVGDGAWGQSLHEISTAVQYKLP 469


>UniRef50_Q88U88 Cluster: Pyruvate oxidase; n=5;
           Lactobacillaceae|Rep: Pyruvate oxidase - Lactobacillus
           plantarum
          Length = 585

 Score = 36.3 bits (80), Expect = 0.72
 Identities = 26/90 (28%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
 Frame = +1

Query: 253 RFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSE-GANTMDIGRGLLLNNHPRHRL-D 426
           ++++  +  T  PL Y  V++ + +    D++   + G NT++  R L +N  P+ +L  
Sbjct: 351 QYLKKLSERTTDPLEYEQVYQEINRVAADDAVFSMDVGDNTINSFRFLKMN--PKQKLLT 408

Query: 427 AGTFGTMGVGPGFAIAAAMWCRDYAPGNVS 516
           +  F TMG G   AIAA M   D    N++
Sbjct: 409 SALFATMGAGVPGAIAAKMSYPDRQAFNIA 438


>UniRef50_Q01Q83 Cluster: Thiamine pyrophosphate enzyme domain
           protein TPP-binding; n=1; Solibacter usitatus
           Ellin6076|Rep: Thiamine pyrophosphate enzyme domain
           protein TPP-binding - Solibacter usitatus (strain
           Ellin6076)
          Length = 548

 Score = 36.3 bits (80), Expect = 0.72
 Identities = 27/94 (28%), Positives = 41/94 (43%)
 Frame = +1

Query: 310 FKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWC 489
           F  ++  +P+D +   +G +    GR +L   H    L  G  GT+G     AIA  +  
Sbjct: 357 FHALRDALPEDVLFSWDGGDFAHWGRAILPARHAGGWLRLGPLGTIGSSLPNAIALQL-- 414

Query: 490 RDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
               PG     +     LGF   E++T  R+KLP
Sbjct: 415 --AHPGRRVVAITGDGALGFYLAEMDTAARFKLP 446



 Score = 35.5 bits (78), Expect = 1.3
 Identities = 17/53 (32%), Positives = 29/53 (54%)
 Frame = +2

Query: 11  RMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVK 169
           R+++ L  G P  +  D K IQV++ P+E   ++  + A+  D R   EAL +
Sbjct: 270 RIDYRLALGGPRLFPADAKFIQVDLHPQELGMNRPLDAAILGDARLALEALTE 322


>UniRef50_UPI000150A350 Cluster: Thiamine pyrophosphate enzyme,
           central domain containing protein; n=1; Tetrahymena
           thermophila SB210|Rep: Thiamine pyrophosphate enzyme,
           central domain containing protein - Tetrahymena
           thermophila SB210
          Length = 561

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 14/30 (46%), Positives = 21/30 (70%)
 Frame = +2

Query: 14  MNWMLHFGQPPRYAPDVKIIQVEISPEEFH 103
           +NW+L FGQ P++  D +IIQ+   PE F+
Sbjct: 285 LNWILDFGQYPQFNRDAQIIQIFNDPEYFN 314


>UniRef50_Q4SYZ1 Cluster: Chromosome 10 SCAF11883, whole genome
            shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 10
            SCAF11883, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1301

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 32/126 (25%), Positives = 58/126 (46%), Gaps = 5/126 (3%)
 Frame = +1

Query: 181  KEVLIATSKQQLVAGTETETKSKH-RFVEAQASSTAVPLNYYTV--FKTVQQGIPKDSII 351
            K++ +    +QLV  T TETK  + R+ E       + LN+ T+   +++ Q +   +I+
Sbjct: 792  KDLSLGQGLEQLVRNTATETKFHYRRYKELSGFLRGLMLNFPTITSLRSLSQSVEFRTIL 851

Query: 352  VSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAI-AAAMWCRDYAPG-NVSFVL 525
              E +N           + P+ R  AG  G   VG    +  AA  C +Y    N++ ++
Sbjct: 852  ALEISNKPQEPE----PSKPKIRFVAGIHGNAPVGTALLLELAAFLCINYGKNPNITRLI 907

Query: 526  KETLLL 543
             ET ++
Sbjct: 908  NETRIV 913


>UniRef50_Q5LKS2 Cluster: Sulphoacetaldehyde acetyltransferase,
           putative; n=1; Silicibacter pomeroyi|Rep:
           Sulphoacetaldehyde acetyltransferase, putative -
           Silicibacter pomeroyi
          Length = 559

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 25/108 (23%), Positives = 49/108 (45%)
 Frame = +1

Query: 268 QASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTM 447
           +A    +P++       ++  +P+D+I+  +  NT       L +  P   +    FG +
Sbjct: 358 EALVETLPMHPRRALGELRNTLPEDAIVTLDTGNTCLQAADRLAHYAPMSLITPLDFGLV 417

Query: 448 GVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           G    F +AAA+  +  AP      +     +G++ +EI+T   +KLP
Sbjct: 418 G----FGLAAAIGAKAAAPERPVVAIMGDGAVGYTMIEIQTAISHKLP 461


>UniRef50_A4ABB6 Cluster: Pyruvate decarboxylase; n=2;
           Proteobacteria|Rep: Pyruvate decarboxylase -
           Congregibacter litoralis KT71
          Length = 565

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 27/93 (29%), Positives = 43/93 (46%)
 Frame = +1

Query: 301 YTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAA 480
           Y++   V   + +++I V +G + +   R  +  +     LD G  G +GVG  FA AAA
Sbjct: 365 YSLIDAVNAHVDEETIAVIDGGDILSFARVAI--SDAAALLDPGALGCIGVGGAFANAAA 422

Query: 481 MWCRDYAPGNVSFVLKETLLLGFSGMEIETMFR 579
           + C+   P      +      GF+ MEI T  R
Sbjct: 423 L-CQ---PDKKVVAVIGDGSFGFNAMEIHTSSR 451


>UniRef50_Q6LF61 Cluster: Putative bi-functional enzyme: long-chain
            fatty-acid Co-A ligase and oxalyl Co-A decarboxylase;
            n=1; Plasmodium falciparum 3D7|Rep: Putative
            bi-functional enzyme: long-chain fatty-acid Co-A ligase
            and oxalyl Co-A decarboxylase - Plasmodium falciparum
            (isolate 3D7)
          Length = 1392

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 27/81 (33%), Positives = 40/81 (49%)
 Frame = +1

Query: 346  IIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVL 525
            II +EG+ T+++G   L    P   +     G MGV    +I+AA+      P N+ F +
Sbjct: 1204 IITNEGSITLNLGILYLPKFGPYSYVIPQINGMMGVSMNASISAAL----DNPNNIIFSI 1259

Query: 526  KETLLLGFSGMEIETMFRYKL 588
                  GF+  EIET+ R KL
Sbjct: 1260 LGDSSFGFTSNEIETICRLKL 1280


>UniRef50_P08142 Cluster: Acetolactate synthase isozyme 1 large
           subunit; n=49; Bacteria|Rep: Acetolactate synthase
           isozyme 1 large subunit - Escherichia coli (strain K12)
          Length = 562

 Score = 35.5 bits (78), Expect = 1.3
 Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
 Frame = +1

Query: 289 PLNYYTVFKTVQQGIPKDSIIVSE-GANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGF 465
           PL++Y +   V   +  ++II ++ G + M   +   LN  PR  L +G  GTMG G   
Sbjct: 367 PLSHYGLINAVAACVDDNAIITTDVGQHQMWTAQAYPLNR-PRQWLTSGGLGTMGFGLPA 425

Query: 466 AIAAAM 483
           AI AA+
Sbjct: 426 AIGAAL 431


>UniRef50_Q6AJI2 Cluster: Acetolactate synthase; n=42; cellular
           organisms|Rep: Acetolactate synthase - Desulfotalea
           psychrophila
          Length = 612

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
 Frame = +1

Query: 307 VFKTVQQGIPKDSIIVSE-GANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAM 483
           V +T+ +    ++II +E G N M   +    N HPRH + +G  GTMG G   AI A M
Sbjct: 423 VVETIDRLTKGEAIITTEVGQNQMWAAQFYKFN-HPRHFVTSGGLGTMGFGLPAAIGAQM 481


>UniRef50_A0C0T8 Cluster: Chromosome undetermined scaffold_140,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_140,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 769

 Score = 35.1 bits (77), Expect = 1.7
 Identities = 24/124 (19%), Positives = 55/124 (44%)
 Frame = +1

Query: 178 RKEVLIATSKQQLVAGTETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVS 357
           ++ ++I+  ++Q +AG++    S  + VE Q        NY    +++ + +   +  V+
Sbjct: 10  KQSIIISKKEKQFIAGSDVVYNSLKKLVEQQKEYGNKHSNYVLGIQSIIEDLSTKTFTVT 69

Query: 358 EGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETL 537
              +   I    +  + P+H++    F  + +  GF     +  R+  P N+ F  ++ L
Sbjct: 70  YNCDESAIPLSKIQYSSPKHKIQ--IFKYLYLIYGFLNKEKILHRNLKPNNIIFYNQQLL 127

Query: 538 LLGF 549
           L  F
Sbjct: 128 LTDF 131


>UniRef50_Q5LKG3 Cluster: Acetolactate synthase, large subunit,
           putative; n=11; Proteobacteria|Rep: Acetolactate
           synthase, large subunit, putative - Silicibacter
           pomeroyi
          Length = 563

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
 Frame = +1

Query: 220 AGTETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSE-GANTMDIGRGLL 396
           A  E +T+    F E  A S   P+    V + +   +P+D+ +VS+ G +         
Sbjct: 353 AVAEKKTRKFEAF-EVLARSDQAPIRPERVIRALMNTLPEDATVVSDPGTSCPYFSAYYQ 411

Query: 397 LNNHPRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMF 576
           L    RH +     G +G    ++++AA+      P + +  L     LGF+  E+ET+ 
Sbjct: 412 LPRPGRHFITNRAHGALG----YSLSAALGAWYGRPASKTVALMGDGSLGFTVGELETVC 467

Query: 577 RYKLP 591
           R + P
Sbjct: 468 RSRAP 472


>UniRef50_Q1ARE6 Cluster: Acetolactate synthase; n=4; Bacteria|Rep:
           Acetolactate synthase - Rubrobacter xylanophilus (strain
           DSM 9941 / NBRC 16129)
          Length = 564

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 2/87 (2%)
 Frame = +2

Query: 35  GQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERKFSLQPQNN- 211
           G P R+AP+ +++ ++I P E     K  + + +D R     +++ +       +PQ+N 
Sbjct: 291 GDPSRFAPNARVVHIDIDPSELGKVIKPAVGIAADARAALRGVLRHIG------RPQDNC 344

Query: 212 -SWWQGLKQKQKANTDL*RLKQAALQY 289
            +W   + + Q+   +  R ++A  +Y
Sbjct: 345 AAWRAEIAESQRPERE--RAERARPEY 369


>UniRef50_A1ICC6 Cluster: Putative TPP-requiring enzyme; n=1;
           Candidatus Desulfococcus oleovorans Hxd3|Rep: Putative
           TPP-requiring enzyme - Candidatus Desulfococcus
           oleovorans Hxd3
          Length = 557

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 16/58 (27%), Positives = 30/58 (51%)
 Frame = +2

Query: 11  RMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSER 184
           R NW+L  G      PD K+I+++I P E   ++ +++ +  D     E L+  + +R
Sbjct: 278 RFNWVLQSGS---LFPDAKVIRIDIDPAELDRNRAADVGLAGDAGRVLEQLLPLVEQR 332


>UniRef50_Q5LQV0 Cluster: Benzaldehyde lyase, putative; n=1;
           Silicibacter pomeroyi|Rep: Benzaldehyde lyase, putative
           - Silicibacter pomeroyi
          Length = 576

 Score = 34.3 bits (75), Expect = 2.9
 Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
 Frame = +2

Query: 11  RMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEAL--VKRLSER 184
           R++  ++FG PP   P+ K+I V  S EE   +  +++ + SD   F  AL  +K+  E 
Sbjct: 285 RLDNQMNFGNPPFIQPETKLICVNGSHEELDYNIGADVPLLSDPGAFLTALEGLKKTWEP 344

Query: 185 KFSLQPQNNSWW 220
              LQ Q    W
Sbjct: 345 WLDLQIQRRRDW 356


>UniRef50_Q2U8M9 Cluster: Thiamine pyrophosphate-requiring enzymes;
           n=2; Trichocomaceae|Rep: Thiamine
           pyrophosphate-requiring enzymes - Aspergillus oryzae
          Length = 597

 Score = 34.3 bits (75), Expect = 2.9
 Identities = 28/100 (28%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
 Frame = +1

Query: 292 LNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRL-DAGTFGTMGVGPGFA 468
           L+ Y   K +   +PK+SII+ +G         ++    P   +  +G  G +G G G+A
Sbjct: 384 LHPYHALKHLLTFVPKESIIILDGGEAPLWAGEMISTCSPSAIVKSSGGLGFLGNGFGYA 443

Query: 469 IAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           + AA+ C D    N    L      GF  M+++T  R+ L
Sbjct: 444 LGAAVACPDQTVIN----LHGDGSAGFHFMDLDTYKRHNL 479


>UniRef50_Q18S72 Cluster: Thiamine pyrophosphate enzyme-like TPP
           binding region; n=2; Desulfitobacterium hafniense|Rep:
           Thiamine pyrophosphate enzyme-like TPP binding region -
           Desulfitobacterium hafniense (strain DCB-2)
          Length = 591

 Score = 33.9 bits (74), Expect = 3.9
 Identities = 18/57 (31%), Positives = 27/57 (47%)
 Frame = +2

Query: 35  GQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERKFSLQPQ 205
           G   R+    K++ V +   E      +ELAV +DIR F E  +  L ++ F   PQ
Sbjct: 307 GDSQRFQSGRKVVHVNLDNRELSRHISTELAVAADIRDFLEHFLAFLRDKGFIPTPQ 363


>UniRef50_A3VG64 Cluster: Acetolactate synthase large subunit; n=1;
           Rhodobacterales bacterium HTCC2654|Rep: Acetolactate
           synthase large subunit - Rhodobacterales bacterium
           HTCC2654
          Length = 539

 Score = 33.9 bits (74), Expect = 3.9
 Identities = 16/64 (25%), Positives = 31/64 (48%)
 Frame = +1

Query: 292 LNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAI 471
           +++ T    +   +P D  +V++    M    GLL    PR  + + +FG +G+G   A+
Sbjct: 358 VDFLTTLARLNDILPSDRTLVTDAGRWMVKSYGLLTAPGPRDHVTSASFGAIGLGLATAV 417

Query: 472 AAAM 483
            A +
Sbjct: 418 GAGV 421


>UniRef50_Q8EN64 Cluster: Acetolactate synthase; n=24; cellular
           organisms|Rep: Acetolactate synthase - Oceanobacillus
           iheyensis
          Length = 573

 Score = 33.5 bits (73), Expect = 5.1
 Identities = 18/69 (26%), Positives = 34/69 (49%)
 Frame = +2

Query: 35  GQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERKFSLQPQNNS 214
           G    +AP+ KI+ ++I P E   + ++ + V +D +    AL+K  +E+       + +
Sbjct: 300 GNIKHFAPNAKIVHIDIDPAEIGKNIETNIPVVADAKRALTALLKNTTEK-----CDHQN 354

Query: 215 WWQGLKQKQ 241
           W   LK  Q
Sbjct: 355 WLHQLKHNQ 363


>UniRef50_A5US79 Cluster: Thiamine pyrophosphate enzyme, central
           region precursor; n=3; Chloroflexaceae|Rep: Thiamine
           pyrophosphate enzyme, central region precursor -
           Roseiflexus sp. RS-1
          Length = 847

 Score = 33.5 bits (73), Expect = 5.1
 Identities = 26/101 (25%), Positives = 45/101 (44%)
 Frame = +1

Query: 289 PLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFA 468
           P++   + + +   +P+++I V +G  +       L    P      G+ G +GVG GFA
Sbjct: 657 PMHSIQLMQALATCLPREAIKVVDGGYSAAFAIQYLDATVPGGVTWVGSTGHIGVGLGFA 716

Query: 469 IAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           I A    R   P +    +      G  G+E +T  R++LP
Sbjct: 717 IGA----RLAHPDSPVVAIMGDGAFGLCGLEFDTAVRHQLP 753


>UniRef50_A4A7Q3 Cluster: Acetolactate synthase large subunit; n=2;
           Proteobacteria|Rep: Acetolactate synthase large subunit
           - Congregibacter litoralis KT71
          Length = 514

 Score = 33.5 bits (73), Expect = 5.1
 Identities = 20/68 (29%), Positives = 33/68 (48%)
 Frame = +1

Query: 292 LNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTMGVGPGFAI 471
           LN  T+ + +   +P+ +++  EGA T  +   +   N P H     T G +G G   A+
Sbjct: 337 LNPLTIGQIMSNEMPEHAVVSDEGA-TCGLAMFMCTENAPAHDWLTLTGGAIGQGLPVAL 395

Query: 472 AAAMWCRD 495
            AA+ C D
Sbjct: 396 GAALACPD 403


>UniRef50_A0L5Q9 Cluster: Sensor protein; n=1; Magnetococcus sp.
           MC-1|Rep: Sensor protein - Magnetococcus sp. (strain
           MC-1)
          Length = 1101

 Score = 33.5 bits (73), Expect = 5.1
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
 Frame = -2

Query: 691 VH*VTSPPRLN--ICPLLLYQTHXKFHYCXXXXXLQVTCTGTLSLFPCLRSPKAESPSTQ 518
           VH + SP +LN  +  +L +  H +          QV     L+LFP L   K + P+  
Sbjct: 83  VHSLKSPKQLNDTLTQVLKFSPHLR-QVIIADKEGQVIADSALALFPTLPRVKLDLPALG 141

Query: 517 MTRYQVHSLGTTLLL 473
           +++ ++ SLG  +LL
Sbjct: 142 LSQERLRSLGDRMLL 156


>UniRef50_A2BLQ1 Cluster: Putative uncharacterized protein; n=1;
           Hyperthermus butylicus DSM 5456|Rep: Putative
           uncharacterized protein - Hyperthermus butylicus (strain
           DSM 5456 / JCM 9403)
          Length = 145

 Score = 33.5 bits (73), Expect = 5.1
 Identities = 14/34 (41%), Positives = 24/34 (70%)
 Frame = -1

Query: 698 GWCTLSNIAAQIEYLPITSLSNPLXIPLLFTMII 597
           GW TL+ I+  +E +PIT +S P+ +P + T++I
Sbjct: 97  GWLTLTGISETVEPIPITLISRPV-LPDMLTIVI 129


>UniRef50_Q9CFJ5 Cluster: 1-deoxyxylulose-5-phosphate synthase; n=2;
           Lactococcus lactis|Rep: 1-deoxyxylulose-5-phosphate
           synthase - Lactococcus lactis subsp. lactis
           (Streptococcus lactis)
          Length = 599

 Score = 33.1 bits (72), Expect = 6.7
 Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
 Frame = +1

Query: 274 SSTAVPLNYYTVFKT-VQQGIPK-DSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGTM 447
           SST +  +Y  VF   +++ + K D++I    A  M  G      NHP++ +D G     
Sbjct: 277 SSTNIVRSYNNVFLDFMEEKLAKGDNLIAINAAIPMFFGLSQFAKNHPKNYVDGGIAEQY 336

Query: 448 GVGPGFAIAAA 480
            V  G AIAAA
Sbjct: 337 TVTLGGAIAAA 347


>UniRef50_A3VND4 Cluster: Sensor protein; n=1; Parvularcula
           bermudensis HTCC2503|Rep: Sensor protein - Parvularcula
           bermudensis HTCC2503
          Length = 1044

 Score = 33.1 bits (72), Expect = 6.7
 Identities = 12/30 (40%), Positives = 19/30 (63%)
 Frame = +3

Query: 363 SEYHGYWPRFIAQQSSETQARCWYIWHYGG 452
           + ++GYW  FIA++  ET  + W +  YGG
Sbjct: 275 ANHNGYWEWFIAEEVEETSDQFWRLIGYGG 304


>UniRef50_Q5CR51 Cluster: DHHC family palmitoyl transferase with 4
           transmembrane regions; n=2; Cryptosporidium|Rep: DHHC
           family palmitoyl transferase with 4 transmembrane
           regions - Cryptosporidium parvum Iowa II
          Length = 359

 Score = 33.1 bits (72), Expect = 6.7
 Identities = 13/39 (33%), Positives = 21/39 (53%)
 Frame = +3

Query: 267 SSKQHCSTTELLHCFQNSSTRHSKRFNHCQRRSEYHGYW 383
           SS  +CS  ++ H F   +++H K  N C  R ++H  W
Sbjct: 122 SSNLNCSECKICHLFFEENSKHCKLCNKCIPRYDHHCKW 160


>UniRef50_P07003 Cluster: Pyruvate dehydrogenase [cytochrome] (EC
           1.2.2.2) (Pyruvate oxidase) (POX) (Pyruvate
           dehydrogenase [Ubiquinone]) [Contains: Alpha-peptide];
           n=91; Bacteria|Rep: Pyruvate dehydrogenase [cytochrome]
           (EC 1.2.2.2) (Pyruvate oxidase) (POX) (Pyruvate
           dehydrogenase [Ubiquinone]) [Contains: Alpha-peptide] -
           Escherichia coli (strain K12)
          Length = 572

 Score = 33.1 bits (72), Expect = 6.7
 Identities = 18/50 (36%), Positives = 28/50 (56%), Gaps = 3/50 (6%)
 Frame = +2

Query: 50  YAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEA---LVKRLSERKF 190
           Y  D KIIQ++I+P       K ++A+  DI+    A   LV+  ++RKF
Sbjct: 282 YPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKADRKF 331


>UniRef50_Q186C0 Cluster: Acetolactate synthase; n=2; Clostridium
           difficile|Rep: Acetolactate synthase - Clostridium
           difficile (strain 630)
          Length = 564

 Score = 32.7 bits (71), Expect = 8.9
 Identities = 15/66 (22%), Positives = 37/66 (56%)
 Frame = +2

Query: 50  YAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERKFSLQPQNNSWWQGL 229
           +A + KII ++I P E   + +S +++  D++     L++R+  +       N++W + +
Sbjct: 301 FAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLSLLIERVESK------NNSNWKEEI 354

Query: 230 KQKQKA 247
           K+ +K+
Sbjct: 355 KRFRKS 360


>UniRef50_A0T1B7 Cluster: Acetohydroxy acid synthase; n=1;
           uncultured soil bacterium|Rep: Acetohydroxy acid
           synthase - uncultured soil bacterium
          Length = 110

 Score = 32.7 bits (71), Expect = 8.9
 Identities = 16/63 (25%), Positives = 32/63 (50%)
 Frame = +2

Query: 35  GQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERKFSLQPQNNS 214
           G+   +APD KII  +I P E    ++ ++ +  D+R   E L+   + ++  L+  +  
Sbjct: 3   GRVGAFAPDAKIIHADIDPAEMGKVRRPDVPLVGDVRLTIEDLI--AATKQLGLKQADRK 60

Query: 215 WWQ 223
            W+
Sbjct: 61  AWK 63


>UniRef50_A2ESQ8 Cluster: Surface antigen BspA-like; n=3;
           Trichomonas vaginalis G3|Rep: Surface antigen BspA-like
           - Trichomonas vaginalis G3
          Length = 744

 Score = 32.7 bits (71), Expect = 8.9
 Identities = 17/35 (48%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
 Frame = +3

Query: 267 SSKQHCSTTELLHCFQNSSTR-HSKRFNHCQRRSE 368
           SS  HCS  E +  F NSSTR +S+ F+HC++ S+
Sbjct: 194 SSFSHCSQLEKVR-FLNSSTRLNSQAFSHCEKLSD 227


>UniRef50_P42463 Cluster: Acetolactate synthase large subunit; n=69;
           cellular organisms|Rep: Acetolactate synthase large
           subunit - Corynebacterium glutamicum (Brevibacterium
           flavum)
          Length = 626

 Score = 32.7 bits (71), Expect = 8.9
 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
 Frame = +2

Query: 35  GQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERKFS-LQPQNN 211
           G    +APD KII  +I P E    K+ E+ +  D R   E L + L   K S  + ++ 
Sbjct: 309 GDVDTFAPDAKIIHADIDPAEIGKIKQVEVPIVGDAR---EVLARLLETTKASKAETEDI 365

Query: 212 SWW 220
           S W
Sbjct: 366 SEW 368


>UniRef50_P51853 Cluster: Benzaldehyde lyase; n=3; Pseudomonas
           fluorescens|Rep: Benzaldehyde lyase - Pseudomonas
           fluorescens
          Length = 563

 Score = 32.7 bits (71), Expect = 8.9
 Identities = 28/109 (25%), Positives = 51/109 (46%)
 Frame = +1

Query: 265 AQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHRLDAGTFGT 444
           A  SS+   L+ +   + + + +     +V++GA T      ++    P   L  G  G+
Sbjct: 361 AAKSSSEHALHPFHASQVIAKHVDAGVTVVADGALTYLWLSEVMSRVKPGGFLCHGYLGS 420

Query: 445 MGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           MGVG G A+ A +   D   G  + ++     +G+S  E +T+ R +LP
Sbjct: 421 MGVGFGTALGAQV--ADLEAGRRTILVTGDGSVGYSIGEFDTLVRKQLP 467


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 703,150,010
Number of Sequences: 1657284
Number of extensions: 14358184
Number of successful extensions: 39230
Number of sequences better than 10.0: 67
Number of HSP's better than 10.0 without gapping: 37686
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39184
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 55371905986
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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