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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= prgv0589
         (698 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AJ131753-1|CAB60200.1|  578|Homo sapiens 2-hydroxyphytanoyl-CoA ...   138   2e-32
BC001627-1|AAH01627.1|  578|Homo sapiens 2-hydroxyacyl-CoA lyase...   138   2e-32
AK125241-1|BAC86096.1|  569|Homo sapiens protein ( Homo sapiens ...    91   3e-18
U61263-1|AAC50934.1|  632|Homo sapiens acetolactate synthase hom...    64   3e-10
BC011761-1|AAH11761.1|  632|Homo sapiens ilvB (bacterial acetola...    64   3e-10
BC011722-1|AAH11722.1|  632|Homo sapiens ilvB (bacterial acetola...    64   3e-10
AC004794-3|AAC18916.1|  393|Homo sapiens Acetolactate synthase p...    64   3e-10
AC003956-1|AAB94632.1|  632|Homo sapiens acetolactate synthase p...    64   3e-10

>AJ131753-1|CAB60200.1|  578|Homo sapiens 2-hydroxyphytanoyl-CoA
           lyase protein.
          Length = 578

 Score =  138 bits (334), Expect = 2e-32
 Identities = 67/117 (57%), Positives = 84/117 (71%)
 Frame = +1

Query: 241 KSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHR 420
           KS     +  AS  ++P+NYYTVF  VQ+ +P+D  +VSEGANTMDIGR +L N  PRHR
Sbjct: 358 KSNEAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHR 417

Query: 421 LDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           LDAGTFGTMGVG GFAIAAA+  +D +PG+    ++     GFSGME+ET+ RY LP
Sbjct: 418 LDAGTFGTMGVGLGFAIAAAVVAKDRSPGHWIICVEGDSAFGFSGMEVETICRYNLP 474



 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/81 (43%), Positives = 53/81 (65%)
 Frame = +2

Query: 8   ARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERK 187
           AR+NW+LHFG PPRY PDVK IQV+I  EE  N+ K  + +  +I   T+ L++ L +  
Sbjct: 281 ARLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTP 340

Query: 188 FSLQPQNNSWWQGLKQKQKAN 250
           +   P+ + WW+ L++K K+N
Sbjct: 341 WQYPPE-SKWWKTLREKMKSN 360


>BC001627-1|AAH01627.1|  578|Homo sapiens 2-hydroxyacyl-CoA lyase 1
           protein.
          Length = 578

 Score =  138 bits (333), Expect = 2e-32
 Identities = 67/117 (57%), Positives = 83/117 (70%)
 Frame = +1

Query: 241 KSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNHPRHR 420
           KS     +  AS  ++P+NYYTVF  VQ+ +P+D  +VSEGANTMDIGR +L N  PRHR
Sbjct: 358 KSNEAASKELASKKSLPMNYYTVFYHVQEQLPRDCFVVSEGANTMDIGRTVLQNYLPRHR 417

Query: 421 LDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           LDAGTFGTMGVG GFAIAAA+  +D +PG     ++     GFSGME+ET+ RY LP
Sbjct: 418 LDAGTFGTMGVGLGFAIAAAVVAKDRSPGQWIICVEGDSAFGFSGMEVETICRYNLP 474



 Score = 81.0 bits (191), Expect = 4e-15
 Identities = 35/81 (43%), Positives = 53/81 (65%)
 Frame = +2

Query: 8   ARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERK 187
           AR+NW+LHFG PPRY PDVK IQV+I  EE  N+ K  + +  +I   T+ L++ L +  
Sbjct: 281 ARLNWILHFGLPPRYQPDVKFIQVDICAEELGNNVKPAVTLLGNIHAVTKQLLEELDKTP 340

Query: 188 FSLQPQNNSWWQGLKQKQKAN 250
           +   P+ + WW+ L++K K+N
Sbjct: 341 WQYPPE-SKWWKTLREKMKSN 360


>AK125241-1|BAC86096.1|  569|Homo sapiens protein ( Homo sapiens
           cDNA FLJ43251 fis, clone HEART2006131, weakly  similar
           to Mus musculus 2-hydroxyphytanoyl-CoA lyase
           (Hpcl-pending). ).
          Length = 569

 Score = 91.5 bits (217), Expect = 3e-18
 Identities = 55/116 (47%), Positives = 71/116 (61%), Gaps = 1/116 (0%)
 Frame = +1

Query: 247 KHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSII-VSEGANTMDIGRGLLLNNHPRHRL 423
           K +   ++ S +A+ LNY T F  ++  +P++ I+ VSEGANTMDIGR     + PRHRL
Sbjct: 356 KTKTAGSKGSDSAI-LNYSTAFTVIKSLLPENDIVYVSEGANTMDIGRSYFDVHEPRHRL 414

Query: 424 DAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKLP 591
           DAGT  TMGVG G+AI A  +  D A   VS V       GFS ME+ET  R +LP
Sbjct: 415 DAGTGATMGVGMGYAIGAQSYYGD-AKRVVSIVGDSA--FGFSAMELETAIRSRLP 467



 Score = 60.1 bits (139), Expect = 7e-09
 Identities = 36/124 (29%), Positives = 67/124 (54%)
 Frame = +2

Query: 8   ARMNWMLHFGQPPRYAPDVKIIQVEISPEEFHNSKKSELAVHSDIRPFTEALVKRLSERK 187
           AR+NW+LH+G  PR++  V+ IQ++I+PEE  N+++  L +  DI+     + + L+ + 
Sbjct: 276 ARLNWILHYGHSPRWSNKVRFIQIDIAPEELGNNRQDTLPLLGDIQLVVSQITQALTGKL 335

Query: 188 FSLQPQNNSWWQGLKQKQKANTDL*RLKQAALQYH*TTTLFSKQFNKAFQKIQSLSAKER 367
            ++ P    +  GL  K K N +  + K A  +   +  L    ++ AF  I+SL  +  
Sbjct: 336 SNINP---DYVSGLVNKVKQNVE--KTKTAGSKGSDSAIL---NYSTAFTVIKSLLPEND 387

Query: 368 IPWI 379
           I ++
Sbjct: 388 IVYV 391


>U61263-1|AAC50934.1|  632|Homo sapiens acetolactate synthase
           homolog protein.
          Length = 632

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 40/121 (33%), Positives = 62/121 (51%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 408
           E + + +  F E  A   A  LN   V + V++ +P +SI+V +G + +     L+    
Sbjct: 424 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 483

Query: 409 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           P   LD G FGT+GVG GFA+ A + CR   P    + L      G+S +E +T  R+K+
Sbjct: 484 PLRWLDPGAFGTLGVGAGFALGAKL-CR---PDAEVWCLFGDGAFGYSLIEFDTFVRHKI 539

Query: 589 P 591
           P
Sbjct: 540 P 540


>BC011761-1|AAH11761.1|  632|Homo sapiens ilvB (bacterial
           acetolactate synthase)-like protein.
          Length = 632

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 40/121 (33%), Positives = 62/121 (51%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 408
           E + + +  F E  A   A  LN   V + V++ +P +SI+V +G + +     L+    
Sbjct: 424 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 483

Query: 409 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           P   LD G FGT+GVG GFA+ A + CR   P    + L      G+S +E +T  R+K+
Sbjct: 484 PLRWLDPGAFGTLGVGAGFALGAKL-CR---PDAEVWCLFGDGAFGYSLIEFDTFVRHKI 539

Query: 589 P 591
           P
Sbjct: 540 P 540


>BC011722-1|AAH11722.1|  632|Homo sapiens ilvB (bacterial
           acetolactate synthase)-like protein.
          Length = 632

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 40/121 (33%), Positives = 62/121 (51%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 408
           E + + +  F E  A   A  LN   V + V++ +P +SI+V +G + +     L+    
Sbjct: 424 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 483

Query: 409 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           P   LD G FGT+GVG GFA+ A + CR   P    + L      G+S +E +T  R+K+
Sbjct: 484 PLRWLDPGAFGTLGVGAGFALGAKL-CR---PDAEVWCLFGDGAFGYSLIEFDTFVRHKI 539

Query: 589 P 591
           P
Sbjct: 540 P 540


>AC004794-3|AAC18916.1|  393|Homo sapiens Acetolactate synthase
           protein.
          Length = 393

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 40/121 (33%), Positives = 62/121 (51%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 408
           E + + +  F E  A   A  LN   V + V++ +P +SI+V +G + +     L+    
Sbjct: 185 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 244

Query: 409 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           P   LD G FGT+GVG GFA+ A + CR   P    + L      G+S +E +T  R+K+
Sbjct: 245 PLRWLDPGAFGTLGVGAGFALGAKL-CR---PDAEVWCLFGDGAFGYSLIEFDTFVRHKI 300

Query: 589 P 591
           P
Sbjct: 301 P 301


>AC003956-1|AAB94632.1|  632|Homo sapiens acetolactate synthase
           protein.
          Length = 632

 Score = 64.5 bits (150), Expect = 3e-10
 Identities = 40/121 (33%), Positives = 62/121 (51%)
 Frame = +1

Query: 229 ETETKSKHRFVEAQASSTAVPLNYYTVFKTVQQGIPKDSIIVSEGANTMDIGRGLLLNNH 408
           E + + +  F E  A   A  LN   V + V++ +P +SI+V +G + +     L+    
Sbjct: 424 EADRQKEQTFREKAAMPVAQHLNPVQVLQLVEETLPDNSILVVDGGDFVGTAAHLVQPRG 483

Query: 409 PRHRLDAGTFGTMGVGPGFAIAAAMWCRDYAPGNVSFVLKETLLLGFSGMEIETMFRYKL 588
           P   LD G FGT+GVG GFA+ A + CR   P    + L      G+S +E +T  R+K+
Sbjct: 484 PLRWLDPGAFGTLGVGAGFALGAKL-CR---PDAEVWCLFGDGAFGYSLIEFDTFVRHKI 539

Query: 589 P 591
           P
Sbjct: 540 P 540


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,036,360
Number of Sequences: 237096
Number of extensions: 2353821
Number of successful extensions: 9267
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 9016
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9256
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8063224416
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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