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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= prgv0526
         (560 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC009703-1|AAH09703.1|  192|Homo sapiens SEC11 homolog C (S. cer...   154   2e-37
AF212233-1|AAK14919.1|  192|Homo sapiens microsomal signal pepti...   154   2e-37
CR457127-1|CAG33408.1|  179|Homo sapiens SPC18 protein.               154   2e-37
BC014508-1|AAH14508.1|  179|Homo sapiens SEC11 homolog A (S. cer...   154   2e-37
BC000359-1|AAH00359.3|  179|Homo sapiens SEC11 homolog A (S. cer...   154   2e-37
AF108945-1|AAD19640.1|  179|Homo sapiens signal peptidase 18 kDa...   154   2e-37
AF090315-1|AAC36354.1|  167|Homo sapiens signal peptidase comple...   154   2e-37
AF087906-1|AAP97204.1|  188|Homo sapiens signal peptidase comple...   154   2e-37
AF061737-1|AAD17526.1|  179|Homo sapiens microsomal signal pepti...   154   2e-37
AK223224-1|BAD96944.1|  179|Homo sapiens signal peptidase comple...   153   5e-37
AF147791-1|AAD55679.1|  957|Homo sapiens mucin 11 protein.             32   1.2  
AY129010-1|AAM98753.1|  198|Homo sapiens unknown protein.              30   6.4  
BC030284-1|AAH30284.1|  410|Homo sapiens TMEM117 protein protein.      29   8.5  

>BC009703-1|AAH09703.1|  192|Homo sapiens SEC11 homolog C (S.
           cerevisiae) protein.
          Length = 192

 Score =  154 bits (374), Expect = 2e-37
 Identities = 69/84 (82%), Positives = 80/84 (95%)
 Frame = +3

Query: 6   RGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRVGEIVVFKVEGRDIPIVH 185
           +GL+V+TGSESPIVVVLSGSMEPAFHRGDLLFLTN+ E+P+R GEIVVFKVEGRDIPIVH
Sbjct: 49  KGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVH 108

Query: 186 RVLKLHEKNNGTVKFLTKGDNNSL 257
           RV+K+HEK+NG +KFLTKGDNN +
Sbjct: 109 RVIKVHEKDNGDIKFLTKGDNNEV 132



 Score =  101 bits (243), Expect = 1e-21
 Identities = 45/60 (75%), Positives = 52/60 (86%)
 Frame = +2

Query: 254 LDDRGLYAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHRE 433
           +DDRGLY +GQ WL KKDVVGRARGFLPYVGMVTI MN+YPKFK+A+LA +  YVL+ RE
Sbjct: 132 VDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191


>AF212233-1|AAK14919.1|  192|Homo sapiens microsomal signal
           peptidase subunit protein.
          Length = 192

 Score =  154 bits (374), Expect = 2e-37
 Identities = 69/84 (82%), Positives = 80/84 (95%)
 Frame = +3

Query: 6   RGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRVGEIVVFKVEGRDIPIVH 185
           +GL+V+TGSESPIVVVLSGSMEPAFHRGDLLFLTN+ E+P+R GEIVVFKVEGRDIPIVH
Sbjct: 49  KGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFLTNFREDPIRAGEIVVFKVEGRDIPIVH 108

Query: 186 RVLKLHEKNNGTVKFLTKGDNNSL 257
           RV+K+HEK+NG +KFLTKGDNN +
Sbjct: 109 RVIKVHEKDNGDIKFLTKGDNNEV 132



 Score =  101 bits (243), Expect = 1e-21
 Identities = 45/60 (75%), Positives = 52/60 (86%)
 Frame = +2

Query: 254 LDDRGLYAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFKFAVLACLAIYVLVHRE 433
           +DDRGLY +GQ WL KKDVVGRARGFLPYVGMVTI MN+YPKFK+A+LA +  YVL+ RE
Sbjct: 132 VDDRGLYKEGQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191


>CR457127-1|CAG33408.1|  179|Homo sapiens SPC18 protein.
          Length = 179

 Score =  154 bits (373), Expect = 2e-37
 Identities = 69/84 (82%), Positives = 80/84 (95%)
 Frame = +3

Query: 6   RGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRVGEIVVFKVEGRDIPIVH 185
           +GLMV+TGSESPIVVVLSGSMEPAFHRGDLLFLTN  E+P+RVGEIVVF++EGR+IPIVH
Sbjct: 37  KGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVH 96

Query: 186 RVLKLHEKNNGTVKFLTKGDNNSL 257
           RVLK+HEK NG +KFLTKGDNN++
Sbjct: 97  RVLKIHEKQNGHIKFLTKGDNNAV 120



 Score =  105 bits (251), Expect = 1e-22
 Identities = 48/76 (63%), Positives = 59/76 (77%)
 Frame = +2

Query: 206 KEQWHSKVLNQR*Q**LDDRGLYAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFK 385
           K+  H K L +     +DDRGLY QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK
Sbjct: 104 KQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFK 163

Query: 386 FAVLACLAIYVLVHRE 433
           +AVL  L ++VLVHR+
Sbjct: 164 YAVLFLLGLFVLVHRD 179


>BC014508-1|AAH14508.1|  179|Homo sapiens SEC11 homolog A (S.
           cerevisiae) protein.
          Length = 179

 Score =  154 bits (373), Expect = 2e-37
 Identities = 69/84 (82%), Positives = 80/84 (95%)
 Frame = +3

Query: 6   RGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRVGEIVVFKVEGRDIPIVH 185
           +GLMV+TGSESPIVVVLSGSMEPAFHRGDLLFLTN  E+P+RVGEIVVF++EGR+IPIVH
Sbjct: 37  KGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVH 96

Query: 186 RVLKLHEKNNGTVKFLTKGDNNSL 257
           RVLK+HEK NG +KFLTKGDNN++
Sbjct: 97  RVLKIHEKQNGHIKFLTKGDNNAV 120



 Score =  106 bits (254), Expect = 6e-23
 Identities = 49/76 (64%), Positives = 59/76 (77%)
 Frame = +2

Query: 206 KEQWHSKVLNQR*Q**LDDRGLYAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFK 385
           K+  H K L +     +DDRGLY QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK
Sbjct: 104 KQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFK 163

Query: 386 FAVLACLAIYVLVHRE 433
           +AVL  L ++VLVHRE
Sbjct: 164 YAVLFLLGLFVLVHRE 179


>BC000359-1|AAH00359.3|  179|Homo sapiens SEC11 homolog A (S.
           cerevisiae) protein.
          Length = 179

 Score =  154 bits (373), Expect = 2e-37
 Identities = 69/84 (82%), Positives = 80/84 (95%)
 Frame = +3

Query: 6   RGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRVGEIVVFKVEGRDIPIVH 185
           +GLMV+TGSESPIVVVLSGSMEPAFHRGDLLFLTN  E+P+RVGEIVVF++EGR+IPIVH
Sbjct: 37  KGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVH 96

Query: 186 RVLKLHEKNNGTVKFLTKGDNNSL 257
           RVLK+HEK NG +KFLTKGDNN++
Sbjct: 97  RVLKIHEKQNGHIKFLTKGDNNAV 120



 Score =  106 bits (254), Expect = 6e-23
 Identities = 49/76 (64%), Positives = 59/76 (77%)
 Frame = +2

Query: 206 KEQWHSKVLNQR*Q**LDDRGLYAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFK 385
           K+  H K L +     +DDRGLY QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK
Sbjct: 104 KQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFK 163

Query: 386 FAVLACLAIYVLVHRE 433
           +AVL  L ++VLVHRE
Sbjct: 164 YAVLFLLGLFVLVHRE 179


>AF108945-1|AAD19640.1|  179|Homo sapiens signal peptidase 18 kDa
           subunit protein.
          Length = 179

 Score =  154 bits (373), Expect = 2e-37
 Identities = 69/84 (82%), Positives = 80/84 (95%)
 Frame = +3

Query: 6   RGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRVGEIVVFKVEGRDIPIVH 185
           +GLMV+TGSESPIVVVLSGSMEPAFHRGDLLFLTN  E+P+RVGEIVVF++EGR+IPIVH
Sbjct: 37  KGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVH 96

Query: 186 RVLKLHEKNNGTVKFLTKGDNNSL 257
           RVLK+HEK NG +KFLTKGDNN++
Sbjct: 97  RVLKIHEKQNGHIKFLTKGDNNAV 120



 Score =  105 bits (251), Expect = 1e-22
 Identities = 48/76 (63%), Positives = 59/76 (77%)
 Frame = +2

Query: 206 KEQWHSKVLNQR*Q**LDDRGLYAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFK 385
           K+  H K L +     +DDRGLY QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKF+
Sbjct: 104 KQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFR 163

Query: 386 FAVLACLAIYVLVHRE 433
           +AVL  L ++VLVHRE
Sbjct: 164 YAVLFLLGLFVLVHRE 179


>AF090315-1|AAC36354.1|  167|Homo sapiens signal peptidase complex
           18 kDa subunit protein.
          Length = 167

 Score =  154 bits (373), Expect = 2e-37
 Identities = 69/84 (82%), Positives = 80/84 (95%)
 Frame = +3

Query: 6   RGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRVGEIVVFKVEGRDIPIVH 185
           +GLMV+TGSESPIVVVLSGSMEPAFHRGDLLFLTN  E+P+RVGEIVVF++EGR+IPIVH
Sbjct: 25  KGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVH 84

Query: 186 RVLKLHEKNNGTVKFLTKGDNNSL 257
           RVLK+HEK NG +KFLTKGDNN++
Sbjct: 85  RVLKIHEKQNGHIKFLTKGDNNAV 108



 Score =  105 bits (251), Expect = 1e-22
 Identities = 48/76 (63%), Positives = 59/76 (77%)
 Frame = +2

Query: 206 KEQWHSKVLNQR*Q**LDDRGLYAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFK 385
           K+  H K L +     +DDRGLY QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKF+
Sbjct: 92  KQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFR 151

Query: 386 FAVLACLAIYVLVHRE 433
           +AVL  L ++VLVHRE
Sbjct: 152 YAVLFLLGLFVLVHRE 167


>AF087906-1|AAP97204.1|  188|Homo sapiens signal peptidase complex
           SPC-18 protein.
          Length = 188

 Score =  154 bits (373), Expect = 2e-37
 Identities = 69/84 (82%), Positives = 80/84 (95%)
 Frame = +3

Query: 6   RGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRVGEIVVFKVEGRDIPIVH 185
           +GLMV+TGSESPIVVVLSGSMEPAFHRGDLLFLTN  E+P+RVGEIVVF++EGR+IPIVH
Sbjct: 46  KGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVH 105

Query: 186 RVLKLHEKNNGTVKFLTKGDNNSL 257
           RVLK+HEK NG +KFLTKGDNN++
Sbjct: 106 RVLKIHEKQNGHIKFLTKGDNNAV 129



 Score =  106 bits (254), Expect = 6e-23
 Identities = 49/76 (64%), Positives = 59/76 (77%)
 Frame = +2

Query: 206 KEQWHSKVLNQR*Q**LDDRGLYAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFK 385
           K+  H K L +     +DDRGLY QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK
Sbjct: 113 KQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFK 172

Query: 386 FAVLACLAIYVLVHRE 433
           +AVL  L ++VLVHRE
Sbjct: 173 YAVLFLLGLFVLVHRE 188


>AF061737-1|AAD17526.1|  179|Homo sapiens microsomal signal
           peptidase protein.
          Length = 179

 Score =  154 bits (373), Expect = 2e-37
 Identities = 69/84 (82%), Positives = 80/84 (95%)
 Frame = +3

Query: 6   RGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRVGEIVVFKVEGRDIPIVH 185
           +GLMV+TGSESPIVVVLSGSMEPAFHRGDLLFLTN  E+P+RVGEIVVF++EGR+IPIVH
Sbjct: 37  KGLMVITGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVH 96

Query: 186 RVLKLHEKNNGTVKFLTKGDNNSL 257
           RVLK+HEK NG +KFLTKGDNN++
Sbjct: 97  RVLKIHEKQNGHIKFLTKGDNNAV 120



 Score =  106 bits (254), Expect = 6e-23
 Identities = 49/76 (64%), Positives = 59/76 (77%)
 Frame = +2

Query: 206 KEQWHSKVLNQR*Q**LDDRGLYAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFK 385
           K+  H K L +     +DDRGLY QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK
Sbjct: 104 KQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFK 163

Query: 386 FAVLACLAIYVLVHRE 433
           +AVL  L ++VLVHRE
Sbjct: 164 YAVLFLLGLFVLVHRE 179


>AK223224-1|BAD96944.1|  179|Homo sapiens signal peptidase complex
           (18kD) variant protein.
          Length = 179

 Score =  153 bits (370), Expect = 5e-37
 Identities = 69/84 (82%), Positives = 79/84 (94%)
 Frame = +3

Query: 6   RGLMVVTGSESPIVVVLSGSMEPAFHRGDLLFLTNYPEEPVRVGEIVVFKVEGRDIPIVH 185
           +GLMV TGSESPIVVVLSGSMEPAFHRGDLLFLTN  E+P+RVGEIVVF++EGR+IPIVH
Sbjct: 37  KGLMVTTGSESPIVVVLSGSMEPAFHRGDLLFLTNRVEDPIRVGEIVVFRIEGREIPIVH 96

Query: 186 RVLKLHEKNNGTVKFLTKGDNNSL 257
           RVLK+HEK NG +KFLTKGDNN++
Sbjct: 97  RVLKIHEKQNGHIKFLTKGDNNAV 120



 Score =  106 bits (254), Expect = 6e-23
 Identities = 49/76 (64%), Positives = 59/76 (77%)
 Frame = +2

Query: 206 KEQWHSKVLNQR*Q**LDDRGLYAQGQLWLTKKDVVGRARGFLPYVGMVTIYMNEYPKFK 385
           K+  H K L +     +DDRGLY QGQ WL KKDVVGRARGF+PY+G+VTI MN+YPKFK
Sbjct: 104 KQNGHIKFLTKGDNNAVDDRGLYKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFK 163

Query: 386 FAVLACLAIYVLVHRE 433
           +AVL  L ++VLVHRE
Sbjct: 164 YAVLFLLGLFVLVHRE 179


>AF147791-1|AAD55679.1|  957|Homo sapiens mucin 11 protein.
          Length = 957

 Score = 32.3 bits (70), Expect = 1.2
 Identities = 24/55 (43%), Positives = 30/55 (54%), Gaps = 4/55 (7%)
 Frame = -2

Query: 169 SRPSTLKTTISPTRTGSSG*LVKNSKSPL*KAGSI----LPDSTTTIGLSLPVTT 17
           S P +  TT+SP  T SSG + + S +   + GS      PDSTTT GLS   TT
Sbjct: 329 SSPRSPATTLSPASTTSSG-VSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 382


>AY129010-1|AAM98753.1|  198|Homo sapiens unknown protein.
          Length = 198

 Score = 29.9 bits (64), Expect = 6.4
 Identities = 17/41 (41%), Positives = 19/41 (46%)
 Frame = -3

Query: 315 PTTSFLVSHSWPWAYKPLSSSYYCHLWLRTLLCHCSFHVVS 193
           P  S   SHS PW+ +  S S  CH W R  L H S    S
Sbjct: 53  PPCSLHRSHSPPWSPQK-SHSPLCHSWSRNRLAHGSTRACS 92


>BC030284-1|AAH30284.1|  410|Homo sapiens TMEM117 protein protein.
          Length = 410

 Score = 29.5 bits (63), Expect = 8.5
 Identities = 12/22 (54%), Positives = 14/22 (63%)
 Frame = -2

Query: 397 QHSKLKLRIFIHIYGDHSNIWQ 332
           QH+ L L IF HI  D SN W+
Sbjct: 43  QHNSLSLHIFSHIQHDSSNGWE 64


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 87,012,335
Number of Sequences: 237096
Number of extensions: 1948594
Number of successful extensions: 7642
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7446
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7641
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5646880600
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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