Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= prgv0361
(699 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 130 4e-29
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 128 1e-28
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 117 2e-25
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 115 1e-24
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 113 3e-24
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 112 9e-24
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 111 2e-23
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 104 2e-21
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 104 2e-21
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 104 2e-21
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 104 2e-21
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 104 2e-21
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 103 4e-21
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 103 4e-21
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 103 6e-21
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 102 7e-21
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 102 7e-21
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 102 7e-21
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 101 2e-20
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 101 2e-20
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 100 3e-20
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 100 4e-20
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 100 4e-20
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 100 7e-20
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 99 1e-19
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 97 3e-19
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 97 5e-19
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 97 5e-19
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 96 6e-19
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos... 96 8e-19
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro... 95 2e-18
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 94 3e-18
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 94 3e-18
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 94 3e-18
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 93 4e-18
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 93 4e-18
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 93 6e-18
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 92 1e-17
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 92 1e-17
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 91 2e-17
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 91 2e-17
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al... 91 2e-17
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 91 3e-17
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 91 3e-17
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 90 4e-17
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase... 89 1e-16
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 85 1e-15
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant... 85 2e-15
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 85 2e-15
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph... 83 5e-15
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc... 83 5e-15
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 6e-15
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd... 82 1e-14
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa... 82 1e-14
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 82 1e-14
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 81 2e-14
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 3e-14
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 81 3e-14
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 3e-14
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 78 2e-13
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 77 3e-13
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 3e-13
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 77 4e-13
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 7e-13
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge... 76 7e-13
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 7e-13
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 75 1e-12
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 75 2e-12
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 74 3e-12
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 7e-12
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 7e-12
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21... 72 1e-11
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 72 2e-11
UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 2e-11
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 2e-11
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 71 2e-11
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 71 3e-11
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 70 5e-11
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 5e-11
UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia succinici... 69 8e-11
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 69 8e-11
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n... 69 1e-10
UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20; S... 69 1e-10
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 69 1e-10
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr... 69 1e-10
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 2e-10
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 2e-10
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte... 68 2e-10
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 3e-10
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh... 68 3e-10
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 3e-10
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 4e-10
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 67 4e-10
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ... 67 4e-10
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2... 66 6e-10
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 6e-10
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 66 1e-09
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr... 65 1e-09
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n... 65 1e-09
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 65 1e-09
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th... 65 1e-09
UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 1e-09
UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep: ... 65 2e-09
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe... 65 2e-09
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy... 64 2e-09
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE... 64 3e-09
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl... 64 3e-09
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put... 64 4e-09
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 4e-09
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 4e-09
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 4e-09
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu... 63 6e-09
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ... 63 6e-09
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 63 7e-09
UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08
UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 1e-08
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 62 1e-08
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi... 62 1e-08
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco... 62 2e-08
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 62 2e-08
UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 62 2e-08
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro... 61 2e-08
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge... 61 3e-08
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact... 61 3e-08
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace... 60 4e-08
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2... 60 4e-08
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 5e-08
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 60 5e-08
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 60 5e-08
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc... 60 7e-08
UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 60 7e-08
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put... 60 7e-08
UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 9e-08
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 9e-08
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 9e-08
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro... 59 9e-08
UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6; ... 59 9e-08
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria... 59 1e-07
UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-termi... 59 1e-07
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh... 59 1e-07
UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388... 59 1e-07
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba... 58 2e-07
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 58 2e-07
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R... 58 2e-07
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ... 58 2e-07
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro... 58 2e-07
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom... 58 2e-07
UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related dehyd... 58 3e-07
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es... 58 3e-07
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 58 3e-07
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 57 4e-07
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 57 5e-07
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 57 5e-07
UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to D-3-phosph... 56 8e-07
UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to 3-phosphog... 56 8e-07
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 56 8e-07
UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 56 8e-07
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 56 8e-07
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro... 56 8e-07
UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate dehydro... 56 1e-06
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 56 1e-06
UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1; ... 56 1e-06
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 56 1e-06
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or... 56 1e-06
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c... 55 1e-06
UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6; Bradyrhizobiaceae... 55 1e-06
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 1e-06
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 55 1e-06
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit... 55 1e-06
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n... 55 2e-06
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja... 55 2e-06
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia... 55 2e-06
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro... 55 2e-06
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela... 54 3e-06
UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan... 54 3e-06
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ... 54 3e-06
UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 54 3e-06
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge... 54 3e-06
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 3e-06
UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia ... 54 3e-06
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu... 54 3e-06
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba... 54 4e-06
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 54 4e-06
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci... 54 4e-06
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555... 54 4e-06
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ... 54 4e-06
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le... 53 6e-06
UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3; Gammaprot... 53 6e-06
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 53 6e-06
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 6e-06
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 6e-06
UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1; ... 53 8e-06
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 53 8e-06
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu... 53 8e-06
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 8e-06
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase... 53 8e-06
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 53 8e-06
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put... 53 8e-06
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap... 52 1e-05
UniRef50_Q1R7K3 Cluster: 2-hydroxyacid dehydrogenase; n=7; Enter... 52 1e-05
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 1e-05
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi... 52 1e-05
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ... 52 1e-05
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob... 52 1e-05
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu... 52 1e-05
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 52 1e-05
UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3; ... 52 1e-05
UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ... 52 2e-05
UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Re... 52 2e-05
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace... 52 2e-05
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost... 52 2e-05
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 52 2e-05
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 52 2e-05
UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Re... 52 2e-05
UniRef50_A4R4W0 Cluster: Formate dehydrogenase; n=1; Magnaporthe... 52 2e-05
UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3; Me... 51 2e-05
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re... 51 2e-05
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 51 2e-05
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n... 51 2e-05
UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98; Coe... 51 2e-05
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta... 51 3e-05
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 51 3e-05
UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;... 51 3e-05
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|... 50 4e-05
UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1; ... 50 4e-05
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n... 50 4e-05
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 4e-05
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady... 50 5e-05
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 50 5e-05
UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 5e-05
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 50 5e-05
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 5e-05
UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyac... 50 7e-05
UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase... 50 7e-05
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re... 50 7e-05
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro... 50 7e-05
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 7e-05
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 50 7e-05
UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 49 1e-04
UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 49 1e-04
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=... 49 1e-04
UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1; Flavobact... 49 1e-04
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1... 49 1e-04
UniRef50_Q7X9L3 Cluster: Formate dehydrogenase; n=4; Magnoliophy... 49 1e-04
UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 49 1e-04
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ... 48 2e-04
UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 48 2e-04
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 48 2e-04
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd... 48 2e-04
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba... 48 2e-04
UniRef50_A5VE25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter A... 48 2e-04
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 48 2e-04
UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1; Lacto... 48 2e-04
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 48 2e-04
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst... 48 2e-04
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 2e-04
UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n... 48 2e-04
UniRef50_Q9KEA4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 48 3e-04
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo... 48 3e-04
UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15; Pse... 48 3e-04
UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 3e-04
UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 3e-04
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 48 3e-04
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa... 48 3e-04
UniRef50_P52643 Cluster: D-lactate dehydrogenase; n=118; cellula... 48 3e-04
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 47 4e-04
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella... 47 4e-04
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 4e-04
UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23; Proteoba... 47 4e-04
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 5e-04
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 5e-04
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 5e-04
UniRef50_A1BC99 Cluster: D-isomer specific 2-hydroxyacid dehydro... 47 5e-04
UniRef50_Q0D7C9 Cluster: Os07g0264100 protein; n=5; Oryza sativa... 47 5e-04
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 46 7e-04
UniRef50_Q9C7T6 Cluster: Phosphoglycerate dehydrogenase, putativ... 46 7e-04
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 9e-04
UniRef50_A4AL46 Cluster: Putative dehydrogenase; n=1; marine act... 46 9e-04
UniRef50_UPI0000383A41 Cluster: COG1052: Lactate dehydrogenase a... 46 0.001
UniRef50_Q13ZE9 Cluster: Putative dehydrogenase, D-3-phosphoglyc... 46 0.001
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 46 0.001
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi... 46 0.001
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh... 46 0.001
UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 45 0.002
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col... 45 0.002
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2; ... 45 0.002
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy... 45 0.002
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus... 45 0.002
UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 45 0.002
UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_A4M784 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_A1GFX2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 45 0.002
UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 45 0.002
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu... 44 0.003
UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.003
UniRef50_A5VEE7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.003
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.003
UniRef50_A1WHT1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.003
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified... 44 0.003
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s... 44 0.003
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 44 0.003
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha... 44 0.004
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;... 44 0.004
UniRef50_Q1M6M5 Cluster: Putative glyoxylate reductase; n=1; Rhi... 44 0.004
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar... 44 0.004
UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23; Gammapro... 44 0.005
UniRef50_A6W9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.005
UniRef50_A4TXP1 Cluster: Glycolate reductase; n=1; Magnetospiril... 44 0.005
UniRef50_A1FCW9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.005
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ... 44 0.005
UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia a... 44 0.005
UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 44 0.005
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase... 43 0.006
UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular or... 43 0.006
UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.006
UniRef50_Q398N2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.006
UniRef50_A5IAP7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 43 0.006
UniRef50_A4BPX8 Cluster: Glycerate dehydrogenase; n=1; Nitrococc... 43 0.006
UniRef50_UPI000038E31A Cluster: hypothetical protein Faci_030017... 43 0.008
UniRef50_A5N6P2 Cluster: GyaR; n=1; Clostridium kluyveri DSM 555... 43 0.008
UniRef50_Q9HJV5 Cluster: Glycerate dehydrogenase related protein... 43 0.008
UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.011
UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.011
UniRef50_Q4LAE6 Cluster: Similar to glycerate dehydrogenase; n=1... 42 0.011
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord... 42 0.011
UniRef50_Q120R1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.011
UniRef50_A3JTB6 Cluster: Putative D-isomer specific 2-hydroxyaci... 42 0.011
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 42 0.011
UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep: A... 42 0.011
UniRef50_Q88VJ2 Cluster: D-lactate dehydrogenase; n=27; Lactobac... 42 0.011
UniRef50_Q3KE30 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.015
UniRef50_Q2NVC4 Cluster: Putative 2-hydroxyacid-family dehydroge... 42 0.015
UniRef50_A7STU0 Cluster: Predicted protein; n=5; Nematostella ve... 42 0.015
UniRef50_Q59642 Cluster: D-lactate dehydrogenase; n=5; Pediococc... 42 0.015
UniRef50_Q08911 Cluster: Formate dehydrogenase 1; n=71; Eukaryot... 42 0.015
UniRef50_Q9S2M5 Cluster: Putative D-lactate dehydrogenase; n=1; ... 42 0.019
UniRef50_Q8GC20 Cluster: 3-phosphoglycerate dehydrogenase; n=2; ... 42 0.019
UniRef50_Q126C0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.019
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga... 42 0.019
UniRef50_A6BZW2 Cluster: Putative dehydrogenase; n=1; Planctomyc... 42 0.019
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ... 42 0.019
UniRef50_A5ZA39 Cluster: Putative uncharacterized protein; n=1; ... 42 0.019
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p... 42 0.019
UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 42 0.019
UniRef50_Q47XK1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 42 0.019
UniRef50_Q4SJ39 Cluster: Chromosome 21 SCAF14577, whole genome s... 41 0.025
UniRef50_Q602T7 Cluster: PKD domain protein; n=1; Methylococcus ... 41 0.025
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba... 41 0.025
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto... 41 0.025
UniRef50_A6CXX0 Cluster: Dehydrogenase; n=1; Vibrio shilonii AK1... 41 0.025
UniRef50_A0QVE9 Cluster: Glyoxylate reductase; n=1; Mycobacteriu... 41 0.025
UniRef50_A1D255 Cluster: Glycerate dehydrogenase; n=1; Neosartor... 41 0.025
UniRef50_A5YST2 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha... 41 0.025
UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase C1... 41 0.025
UniRef50_Q87MN8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 41 0.025
UniRef50_Q63YS2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 41 0.034
UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 41 0.034
UniRef50_A3Y4H8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 41 0.034
UniRef50_Q8H423 Cluster: Putative phosphoglycerate dehydrogenase... 41 0.034
UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75; Proteo... 41 0.034
UniRef50_UPI000155367B Cluster: PREDICTED: hypothetical protein;... 40 0.044
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1... 40 0.044
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter... 40 0.044
UniRef50_Q1QXV7 Cluster: Erythronate-4-phosphate dehydrogenase; ... 40 0.044
UniRef50_A4X4V1 Cluster: Putative uncharacterized protein; n=1; ... 40 0.059
UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 40 0.059
UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.059
UniRef50_Q9UBQ7 Cluster: Glyoxylate reductase/hydroxypyruvate re... 40 0.059
UniRef50_A5P5Y8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 40 0.078
UniRef50_A5NPP1 Cluster: Extracellular ligand-binding receptor; ... 40 0.078
UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2; ... 40 0.078
UniRef50_Q99ZM2 Cluster: D-lactate dehydrogenase; n=7; Streptoco... 40 0.078
UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3; Cyanobact... 39 0.10
UniRef50_Q65DI8 Cluster: Putative uncharacterized protein; n=1; ... 39 0.10
UniRef50_Q5NR73 Cluster: 2-hydroxyacid dehydrogenase; n=1; Zymom... 39 0.10
UniRef50_A2SEV8 Cluster: Phosphoglycerate dehydrogenase-related ... 39 0.10
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ... 39 0.10
UniRef50_A7PQ72 Cluster: Chromosome chr18 scaffold_24, whole gen... 39 0.10
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr... 39 0.10
UniRef50_UPI0000D9E051 Cluster: PREDICTED: glyoxylate reductase/... 39 0.14
UniRef50_Q11BV4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.14
UniRef50_Q00TL2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 39 0.14
UniRef50_UPI000023F11E Cluster: hypothetical protein FG10680.1; ... 38 0.18
UniRef50_Q6NUX3 Cluster: Im:7137941 protein; n=3; Danio rerio|Re... 38 0.18
UniRef50_Q88TW9 Cluster: Phosphoglycerate dehydrogenase; n=1; La... 38 0.18
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a... 38 0.18
UniRef50_Q5IW39 Cluster: Putative PhpE; n=2; Actinomycetales|Rep... 38 0.18
UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans Y... 38 0.18
UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1; ... 38 0.18
UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 38 0.18
UniRef50_Q6MIG3 Cluster: Hxdroxypyruvate reductase; n=1; Bdellov... 38 0.24
UniRef50_Q1V300 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 38 0.24
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 38 0.24
UniRef50_A1ZAW3 Cluster: CG6477-PA, isoform A; n=3; Drosophila m... 38 0.24
UniRef50_Q8TFZ8 Cluster: Glycerate dehydrogenase, putative; n=1;... 38 0.24
UniRef50_Q7VRU9 Cluster: Erythronate-4-phosphate dehydrogenase; ... 38 0.24
UniRef50_Q8RC97 Cluster: Phosphoglycerate dehydrogenase and rela... 38 0.31
UniRef50_Q2BM60 Cluster: Erythronate-4-phosphate dehydrogenase; ... 38 0.31
UniRef50_Q76KF6 Cluster: D-glycerate dehydrogenase; n=4; Entamoe... 38 0.31
UniRef50_O14465 Cluster: D-mandelate dehydrogenase; n=1; Rhodoto... 38 0.31
UniRef50_Q8ECR2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 38 0.31
UniRef50_Q5PCV8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 38 0.31
UniRef50_A1SW94 Cluster: Erythronate-4-phosphate dehydrogenase; ... 38 0.31
UniRef50_Q98GE4 Cluster: Phosphoglycerate dehydrogenase; n=5; Rh... 37 0.41
UniRef50_Q62LP5 Cluster: Putative uncharacterized protein; n=2; ... 37 0.41
UniRef50_Q1LFJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.41
UniRef50_A5WBM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.41
UniRef50_A1WAF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.41
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.41
UniRef50_A0R5A8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.41
UniRef50_Q5KKJ8 Cluster: Glyoxylate reductase, putative; n=2; Fi... 37 0.41
UniRef50_Q4PER7 Cluster: Putative uncharacterized protein; n=1; ... 37 0.41
UniRef50_A1CP94 Cluster: Glycerate dehydrogenase; n=4; Trichocom... 37 0.41
UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3; Archaea... 37 0.41
UniRef50_Q8G427 Cluster: Possible 2-hydroxyacid dehydrogenase; n... 37 0.55
UniRef50_Q893I3 Cluster: D-lactate dehydrogenase; n=2; Firmicute... 37 0.55
UniRef50_Q2JEY9 Cluster: Putative uncharacterized protein precur... 37 0.55
UniRef50_Q11AM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 37 0.55
UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1; Prochloroc... 37 0.55
UniRef50_Q8VX85 Cluster: Putative NAD-dependent formate dehydrog... 37 0.55
UniRef50_Q8NIV8 Cluster: Putative uncharacterized protein B13H18... 37 0.55
UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1; ... 37 0.55
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 37 0.55
UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.72
UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;... 36 0.72
UniRef50_Q2CCV7 Cluster: Putative uncharacterized protein; n=1; ... 36 0.72
UniRef50_Q1N6E5 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 0.72
UniRef50_Q1ATD7 Cluster: Glycoside hydrolase 15-related; n=1; Ru... 36 0.72
UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1; ... 36 0.72
UniRef50_A6VXM3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.72
UniRef50_A4FQK7 Cluster: Putative uncharacterized protein; n=1; ... 36 0.72
UniRef50_A1GF52 Cluster: LigA precursor; n=1; Salinispora arenic... 36 0.72
UniRef50_A0NJK9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 36 0.72
UniRef50_Q22328 Cluster: Putative uncharacterized protein T07H6.... 36 0.72
UniRef50_Q5KJK5 Cluster: Glycerate-and formate-dehydrogenase, pu... 36 0.72
UniRef50_Q5K657 Cluster: Hydroxyacid dehydrogenase protein Ynl27... 36 0.72
UniRef50_Q9HSS1 Cluster: Phosphoglycerate dehydrogenase; n=1; Ha... 36 0.72
UniRef50_Q2S0U3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 0.72
UniRef50_Q98ST8 Cluster: Ff1c; n=6; Clupeocephala|Rep: Ff1c - Da... 36 0.96
UniRef50_Q1IPG3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.96
UniRef50_A6TVU1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 0.96
UniRef50_A4BI79 Cluster: D-lactate dehydrogenase; n=1; Reinekea ... 36 0.96
UniRef50_A1ZX42 Cluster: Glycerate dehydrogenase; n=1; Microscil... 36 0.96
UniRef50_Q6EP36 Cluster: Putative uncharacterized protein B1267B... 36 0.96
UniRef50_Q0E2I9 Cluster: Os02g0235200 protein; n=3; Oryza sativa... 36 0.96
UniRef50_A5BY55 Cluster: Putative uncharacterized protein; n=2; ... 36 0.96
UniRef50_A5BPF5 Cluster: Putative uncharacterized protein; n=1; ... 36 0.96
UniRef50_Q5AUK0 Cluster: Putative uncharacterized protein; n=1; ... 36 0.96
UniRef50_A1U1I8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 0.96
UniRef50_Q0VQC3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 0.96
UniRef50_O75112 Cluster: LIM domain-binding protein 3; n=36; Eut... 36 0.96
UniRef50_UPI0000384B5F Cluster: COG0111: Phosphoglycerate dehydr... 36 1.3
UniRef50_Q047V3 Cluster: Lactate dehydrogenase related 2-hydroxy... 36 1.3
UniRef50_Q036G7 Cluster: Lactate dehydrogenase related 2-hydroxy... 36 1.3
UniRef50_A4AK07 Cluster: Glycerate dehydrogenase; n=1; marine ac... 36 1.3
UniRef50_A1CFW0 Cluster: D-mandelate dehydrogenase, putative; n=... 36 1.3
UniRef50_A7I9X3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 36 1.3
UniRef50_Q8D2P6 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 1.3
UniRef50_Q3IF36 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 1.3
UniRef50_Q6LNU2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 1.3
UniRef50_Q5QUE2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 36 1.3
UniRef50_UPI0000F3188A Cluster: Plasma membrane calcium ATPase; ... 35 1.7
UniRef50_Q89Y67 Cluster: Oxidoreductase; n=14; Alphaproteobacter... 35 1.7
UniRef50_A6G855 Cluster: Erythronate-4-phosphate dehydrogenase; ... 35 1.7
UniRef50_A5V3Y8 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19489-PA - Nasonia vitripennis
Length = 511
Score = 130 bits (313), Expect = 4e-29
Identities = 61/107 (57%), Positives = 78/107 (72%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K+VGRAG GVDNID+ +A + G+ V+N PG N++SACELTC ++ LAR+VV A ++K
Sbjct: 70 KLVGRAGTGVDNIDIPAATRNGILVLNTPGGNSVSACELTCAVISALARNVVQAGQSMKE 129
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
GRWDR LY G EL+G+ R+GREVA RM AFGM II +DPF
Sbjct: 130 GRWDRKLYAGRELSGKALGVVGFGRIGREVAHRMKAFGMEIIAYDPF 176
Score = 72.5 bits (170), Expect = 9e-12
Identities = 33/65 (50%), Positives = 48/65 (73%)
Frame = +2
Query: 50 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 229
M V+++SVL+ D V +CA LL ++G+ TTK K+SKEEL+ E+ HD L+VRS T+VT
Sbjct: 1 MSVNLRSVLVSDPVDERCAALLTSHGVPVTTKYKLSKEELINELQKHDGLIVRSETKVTA 60
Query: 230 EVLDA 244
+V+ A
Sbjct: 61 DVIAA 65
>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase - Apis mellifera
Length = 478
Score = 128 bits (310), Expect = 1e-28
Identities = 61/106 (57%), Positives = 78/106 (73%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+VVGRAG GVDNID+++A +KGV V+N PG N++SACELTC L+ LAR+V A +LK
Sbjct: 70 RVVGRAGTGVDNIDLEAATRKGVIVLNTPGGNSISACELTCALISNLARNVTQAVQSLKD 129
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
GRWDR LY+G EL+G+ R+GREV RM A+GM +I FDP
Sbjct: 130 GRWDRKLYSGFELSGKTLAVLGMGRIGREVTRRMQAYGMRVIAFDP 175
Score = 67.7 bits (158), Expect = 3e-10
Identities = 33/62 (53%), Positives = 44/62 (70%)
Frame = +2
Query: 50 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 229
M ++SVLI D V A C ELL +GI TTK K+SKE+L+ E+ NH+ L+VRS T+VT
Sbjct: 1 MSTTLRSVLISDPVDACCGELLVRHGIPVTTKYKLSKEKLIKELQNHEGLIVRSETKVTA 60
Query: 230 EV 235
+V
Sbjct: 61 DV 62
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 117 bits (282), Expect = 2e-25
Identities = 53/113 (46%), Positives = 79/113 (69%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ + +VVGRAG GVDN+D+++A +KG+ V+N P N+LSA ELTC +++ LAR +
Sbjct: 64 INAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQ 123
Query: 415 ASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
A+ ++K G+W+R + G+EL G+ R+GREVATRM +FGM IG+DP
Sbjct: 124 ATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDP 176
Score = 53.6 bits (123), Expect = 4e-06
Identities = 25/65 (38%), Positives = 42/65 (64%)
Frame = +2
Query: 59 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 238
+++ VLI D + C ++L G+ K +SKEEL+ E+ + + L+VRSAT+VT +V+
Sbjct: 5 NLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVI 64
Query: 239 DAGVK 253
+A K
Sbjct: 65 NAAEK 69
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 115 bits (277), Expect = 1e-24
Identities = 55/114 (48%), Positives = 78/114 (68%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ + + KV+GRAG GVDNIDV++A +KG+ V+NAP A+++S ELT LML AR++
Sbjct: 58 IEKAEKLKVIGRAGVGVDNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQ 117
Query: 415 ASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
A+ +LK G WDR + G EL G+ R+G++V R AFGMNIIG+DP+
Sbjct: 118 ATASLKRGEWDRKRFKGIELYGKTLGVIGLGRIGQQVVKRAKAFGMNIIGYDPY 171
Score = 39.5 bits (88), Expect = 0.078
Identities = 21/61 (34%), Positives = 35/61 (57%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 250
+L+ D + ++L G ++KEELL +I + D LVVRS T+VT++V++
Sbjct: 4 ILVTDPLHEDAIKILEEVGEVEVATG-LTKEELLEKIKDADVLVVRSGTKVTRDVIEKAE 62
Query: 251 K 253
K
Sbjct: 63 K 63
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 113 bits (273), Expect = 3e-24
Identities = 53/113 (46%), Positives = 75/113 (66%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ + + +++GRAG GVDNID+++A ++G+ V++ PG NA+SA E TC ++L ARH+
Sbjct: 70 LAKATQLELIGRAGTGVDNIDLEAATRQGIVVMSTPGGNAVSAAEHTCAMLLAAARHIPQ 129
Query: 415 ASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
A LK G W++ LY G EL G+ RVGREVA RM AFGM I +DP
Sbjct: 130 AMADLKQGNWNKHLYAGIELEGKTLSLIGLGRVGREVAMRMQAFGMRTIAYDP 182
Score = 46.8 bits (106), Expect = 5e-04
Identities = 24/60 (40%), Positives = 35/60 (58%)
Frame = +2
Query: 59 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 238
++ VLI D V +C LL +G T K +S +EL I +++ L+VRSAT + EVL
Sbjct: 11 NVMKVLITDSVHPQCGRLLLQHGFEVTEKPSLSPKELHAIIADYNILIVRSATSLPAEVL 70
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 112 bits (269), Expect = 9e-24
Identities = 56/118 (47%), Positives = 73/118 (61%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D + R KV+ RAG G+DN+DV +A + GV V+NAP +N +SA EL LML AR
Sbjct: 64 DAEALAAARRLKVIARAGVGLDNVDVRAATQAGVMVVNAPTSNIVSAAELAVALMLAAAR 123
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
H+ PA ALK G W RA YTG+EL + R+G VA R+ AFGM I+ +DP+
Sbjct: 124 HISPAHAALKNGEWKRARYTGTELYEKTVGIVGLGRIGVLVAQRLSAFGMKIVAYDPY 181
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 111 bits (266), Expect = 2e-23
Identities = 53/109 (48%), Positives = 71/109 (65%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
+ K++GRAG GVDNID +A GV V+N PG N LSA E TC L+ LARH+ AS +
Sbjct: 68 KNLKIIGRAGTGVDNIDTVAASLHGVLVMNTPGGNTLSAAEHTCALISSLARHIPQASAS 127
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
K G+W+R + G+EL G+ R+GREVA RM ++G+ IG+DP
Sbjct: 128 TKEGKWERKQFMGNELFGKTLAIIGLGRIGREVALRMQSYGVKTIGYDP 176
Score = 64.9 bits (151), Expect = 2e-09
Identities = 29/64 (45%), Positives = 44/64 (68%)
Frame = +2
Query: 56 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 235
+++K VLI D V + C +L G+ K+SKEEL+ EIP +D L+VRSAT+V+++V
Sbjct: 4 LELKRVLISDSVDSCCKTILERNGVTVDVNTKLSKEELVSEIPKYDGLIVRSATKVSEDV 63
Query: 236 LDAG 247
+ AG
Sbjct: 64 IKAG 67
Score = 35.1 bits (77), Expect = 1.7
Identities = 22/57 (38%), Positives = 26/57 (45%)
Frame = +2
Query: 479 GKTLAILGLGGSAARWPLGCTPSA*TSSDSTLFVSADQCAQFHCTKMELEDIWPLAD 649
GKTLAI+GLG L + VS A+ + ME E IWPLAD
Sbjct: 145 GKTLAIIGLGRIGREVALRMQSYGVKTIGYDPLVSPQDAAESNIEWMETEKIWPLAD 201
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 104 bits (250), Expect = 2e-21
Identities = 50/110 (45%), Positives = 71/110 (64%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
++ +V+GRAG GVDNID+ +A G+ V+NAP N +SA E T LML +ARH+ A+ +
Sbjct: 62 KKLQVIGRAGVGVDNIDLKTATGNGIIVVNAPTGNTISATEHTLALMLAMARHIPRANAS 121
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
LK+G+W R + GSEL G+ +G E+A R A M +IG+DPF
Sbjct: 122 LKSGQWKRNEFVGSELKGKTLGIVGLGNIGSEIAKRALALEMRVIGYDPF 171
Score = 41.1 bits (92), Expect = 0.025
Identities = 24/64 (37%), Positives = 35/64 (54%)
Frame = +2
Query: 62 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 241
+K VL+ D + A L K + EEL+ I +DAL+VRS TQVT ++++
Sbjct: 1 MKKVLVSDALSATGLAPLKEIA-QVDVKTGLKPEELISIIGEYDALLVRSQTQVTADIIN 59
Query: 242 AGVK 253
AG K
Sbjct: 60 AGKK 63
>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus subtilis
Length = 525
Score = 104 bits (250), Expect = 2e-21
Identities = 52/107 (48%), Positives = 67/107 (62%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K+VGRAG GVDNID+D A K GV VINAP N +S E T ++ L RH+ A+ ++K+
Sbjct: 64 KIVGRAGVGVDNIDIDEATKHGVIVINAPNGNTISTAEHTFAMISSLMRHIPQANISVKS 123
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
W+R Y GSEL G+ R+G E+A R AFGM + FDPF
Sbjct: 124 REWNRTAYVGSELYGKTLGIVGLGRIGSEIAQRRGAFGMTVHVFDPF 170
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 104 bits (249), Expect = 2e-21
Identities = 50/109 (45%), Positives = 68/109 (62%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
+ K++ RAG G+DNIDV A +KG+ V+N PGA+A S EL LML ARH+ A+ +
Sbjct: 65 KNLKIIARAGIGLDNIDVQKAKEKGIKVLNTPGASAPSVAELAMGLMLACARHIARATVS 124
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
LK G+W++ G EL G+ +G+EVA R AFGM II +DP
Sbjct: 125 LKEGKWEKKALKGKELLGKTLGLIGFGNIGQEVAKRALAFGMKIIAYDP 173
Score = 41.5 bits (93), Expect = 0.019
Identities = 22/59 (37%), Positives = 34/59 (57%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 247
V + D + + +LL T + K+EL+ IP D LVVRSAT+VT ++++AG
Sbjct: 6 VHVNDPLDKEATQLLMNKEELEVTSEHLEKDELMKIIPEVDVLVVRSATKVTADIIEAG 64
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 104 bits (249), Expect = 2e-21
Identities = 51/110 (46%), Positives = 69/110 (62%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
++ KVVGRAG GVDNID+ A K+G+ V N P +N +SACELT L+L +R++
Sbjct: 66 KKLKVVGRAGNGVDNIDIPEATKRGIIVANTPDSNTISACELTIGLLLAQSRNIAKTDRF 125
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
LK G WDR + G+EL + R+G VATRM AF M +I +DP+
Sbjct: 126 LKEGNWDRDSFMGTELFNKTLGIIGLGRIGSLVATRMNAFDMKVIAYDPY 175
Score = 39.1 bits (87), Expect = 0.10
Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +2
Query: 56 VDIKSVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 232
+D +LIVD + K ELL + K + +E+LL I N+D L++RS T + E
Sbjct: 1 MDKAKILIVDKIDTKGIELLESEPNFEVDIKMGLEREKLLNIIENYDGLIIRSDTNIDIE 60
Query: 233 VLDAGVK 253
+++ K
Sbjct: 61 LMNMAKK 67
>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
dehydrogenase - Halothermothrix orenii H 168
Length = 527
Score = 104 bits (249), Expect = 2e-21
Identities = 51/118 (43%), Positives = 70/118 (59%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ + + R KV+GRAG G DNID++ A K+G+ V N P N +SA E T +ML L+R
Sbjct: 54 DKEALDKARNLKVIGRAGTGYDNIDIEEASKRGIIVFNTPTGNTISAVEHTIGMMLALSR 113
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
++ A+ AL G WDR Y G E+ G+ R+G VA R AFGM +I DP+
Sbjct: 114 NIPQANQALHEGIWDRKKYMGVEVKGKTLGIIGLGRIGSRVAVRAQAFGMKVIANDPY 171
Score = 39.9 bits (89), Expect = 0.059
Identities = 23/57 (40%), Positives = 31/57 (54%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 241
VL+ D + K E+L T +S+EE L I +D L+VRS T+V KE LD
Sbjct: 4 VLVSDNISPKGIEILEQEA-DVTFNPDLSREEFLDIIGEYDGLIVRSMTEVDKEALD 59
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 103 bits (247), Expect = 4e-21
Identities = 43/110 (39%), Positives = 74/110 (67%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
+ K++GRAG G+DN+DV +A +KG+ V NAP N ++ACE T ++ML ++R++ A+ +
Sbjct: 63 KNLKIIGRAGVGIDNVDVPAATEKGIIVANAPEGNTIAACEHTLSMMLAMSRNIPQANAS 122
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
LK+G+W+R+ + G E+ + R+G E+ R +FGM ++ +DPF
Sbjct: 123 LKSGKWERSKFMGVEVMNKTLGIIGLGRIGGEITKRARSFGMEVLAYDPF 172
Score = 48.4 bits (110), Expect = 2e-04
Identities = 22/60 (36%), Positives = 42/60 (70%), Gaps = 1/60 (1%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 247
VL+ D + + ++L + G+ + +++KE+L+ +I +++AL++RS TQVTKEV+ AG
Sbjct: 3 VLVTDPISEEGIKILKSEPGVQVDIETRLTKEQLIEKIKDYNALIIRSETQVTKEVIAAG 62
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 103 bits (247), Expect = 4e-21
Identities = 49/118 (41%), Positives = 71/118 (60%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D + + K++GRAG GVDNID+++A ++G+ V+NAPG N +S E LML AR
Sbjct: 54 DAEVIQAAKNLKIIGRAGVGVDNIDINAATQRGIVVVNAPGGNTISTAEHAIALMLAAAR 113
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ A ++K G+W+R + G EL G+ RVG EVA R A MN++ +DPF
Sbjct: 114 KIPQADRSVKEGKWERKKFMGIELRGKTAGVIGLGRVGFEVAKRCKALEMNVLAYDPF 171
Score = 47.6 bits (108), Expect = 3e-04
Identities = 20/58 (34%), Positives = 36/58 (62%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
VL+ + + + + + G+ K +S+EEL+ E+P ++A+VVRS T+V EV+ A
Sbjct: 3 VLVAEPISEEAIDYMRKNGLEVEVKTGMSREELIREVPKYEAIVVRSQTKVDAEVIQA 60
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 103 bits (246), Expect = 6e-21
Identities = 53/115 (46%), Positives = 72/115 (62%), Gaps = 1/115 (0%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ R KVVGRAG GVDNIDV +A ++GV V+N PGAN S E L++ +AR++
Sbjct: 56 LARGTRLKVVGRAGVGVDNIDVAAATERGVVVVNVPGANTYSTAEHAFGLLIAVARNIPQ 115
Query: 415 ASTAL-KAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
A AL + GRWDR + G+EL G+ R+G EVA R AFGM ++ +DP+
Sbjct: 116 AHHALAREGRWDRMSFVGTELHGKTLGIIGLGRIGSEVAVRARAFGMRVLAYDPY 170
Score = 41.1 bits (92), Expect = 0.025
Identities = 19/35 (54%), Positives = 25/35 (71%)
Frame = +2
Query: 149 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 253
K++ EELL IP +DAL+ RS T+VT EVL G +
Sbjct: 27 KVTSEELLEIIPEYDALITRSETKVTAEVLARGTR 61
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 102 bits (245), Expect = 7e-21
Identities = 47/109 (43%), Positives = 72/109 (66%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ +V+GRAG GVDNI++++A +KG+ V+N PGANA++ E T LML LAR + A+ +
Sbjct: 65 QLRVIGRAGVGVDNIELEAATRKGIAVMNTPGANAIAVAEHTIGLMLALARFIPRATETM 124
Query: 430 KAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
AG+W++ G+EL G+ R+G EVA R +FGM ++ DP+
Sbjct: 125 HAGKWEKKSLQGTELRGKTLGIVGLGRIGLEVARRAASFGMTLVAHDPY 173
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 102 bits (245), Expect = 7e-21
Identities = 48/107 (44%), Positives = 71/107 (66%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+ RAG GVDNIDVD+A +KG+ V+N+PG N +SA E T +ML L+R++ A + A
Sbjct: 67 RVIARAGVGVDNIDVDAATRKGIIVVNSPGGNTISATEHTLAMMLSLSRNIPQAHKSAAA 126
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G+W+R + G EL + ++G EVA R AFGM ++G+DP+
Sbjct: 127 GKWEREKFKGVELFKKTLGIIGTGKIGTEVAKRAKAFGMAVLGYDPY 173
Score = 33.9 bits (74), Expect = 3.9
Identities = 18/60 (30%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Frame = +2
Query: 68 SVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
++L+ D V + + L A+ + I+ E+L I +D L+VR+ T+VTK++++A
Sbjct: 3 NILVTDKVSEEGLKKLYAHKDFIVEHQPGIAPEDLKATIGQYDGLIVRNQTKVTKDIIEA 62
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 102 bits (245), Expect = 7e-21
Identities = 49/107 (45%), Positives = 71/107 (66%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+ RAG GVDN+D+D+A +KGV V+NAP A+++S EL LML AR++ A+ +LK
Sbjct: 65 KVIARAGVGVDNVDLDAATEKGVVVVNAPDASSISVAELMFGLMLSAARNIPQATASLKK 124
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G WDR + G E+ + R+G++VA R AF MNI+ +DP+
Sbjct: 125 GEWDRKSFKGMEVYAKTLGIVGLGRIGQQVAKRAQAFEMNIVAYDPY 171
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/58 (43%), Positives = 33/58 (56%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
+LI D + E+L G IS EE+ +I + DALVVRS T VTKE++DA
Sbjct: 4 ILITDPLHESAIEILKEAGEVEIATG-ISIEEIKQKIKDADALVVRSGTTVTKEIIDA 60
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 101 bits (242), Expect = 2e-20
Identities = 44/107 (41%), Positives = 71/107 (66%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+GRAG GVDN+D+ +A ++GV V+N PG ++++ EL +++L L+RHV A+ ++KA
Sbjct: 67 KVIGRAGVGVDNVDLAAATRRGVVVMNTPGGSSITVAELALSMILALSRHVAAATGSVKA 126
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G+W++ + G ELAG+ +G + R A GM ++ FDPF
Sbjct: 127 GKWEKKRFQGHELAGRTLGVVGIGNIGSVLVARAVALGMRVVAFDPF 173
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 101 bits (242), Expect = 2e-20
Identities = 50/117 (42%), Positives = 72/117 (61%)
Frame = +1
Query: 226 QRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARH 405
QR + K++GRAG GVDN+DVD+A KKG+ V NAP N +SA E T +M+ ++R+
Sbjct: 71 QRIIEAADNLKIIGRAGVGVDNVDVDAATKKGIIVANAPEGNMISAAEHTIAMMMSMSRN 130
Query: 406 VVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ A+ +LKA W R + G E+ G+ R+G EVA R MN++G+DPF
Sbjct: 131 IPQANASLKAREWKRNKFMGVEVKGKTLGVIGLGRIGSEVAKRAAGLEMNLMGYDPF 187
Score = 38.7 bits (86), Expect = 0.14
Identities = 21/63 (33%), Positives = 39/63 (61%)
Frame = +2
Query: 56 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 235
+D+K VL+ D + + E+L + + ++EL+ +I +DALV+RS TQVT+ +
Sbjct: 16 IDMK-VLVSDSLSNEGLEILKEH-FDIDVCTGLCEDELVEKIKGYDALVIRSGTQVTQRI 73
Query: 236 LDA 244
++A
Sbjct: 74 IEA 76
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 100 bits (240), Expect = 3e-20
Identities = 46/107 (42%), Positives = 68/107 (63%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+GRAG GVDN+D +A +KG+ V+N P NA++ EL TL + ARH+ A+ + KA
Sbjct: 66 KVIGRAGIGVDNVDTPAASQKGIIVMNTPFGNAITTAELGVTLAMAAARHIPAATASTKA 125
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G+W+++ + G ELAG+ VGR VA R+ M ++ +DPF
Sbjct: 126 GKWEKSRFMGRELAGKTAGVIGLGNVGRLVAQRLAGLDMKVVAYDPF 172
Score = 38.3 bits (85), Expect = 0.18
Identities = 19/58 (32%), Positives = 31/58 (53%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
VLI D + E+ A G+ K +S +ELL I +D + +RSAT++ + + A
Sbjct: 4 VLIADKMSPMAEEVFRARGLEVDVKVGMSPDELLACIDQYDGIAIRSATRLPAQAIAA 61
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 100 bits (239), Expect = 4e-20
Identities = 48/107 (44%), Positives = 69/107 (64%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+GRAG GVDNIDV +A +G V+N PGANA +A E T +ML LARH+ A+ +++
Sbjct: 66 KVIGRAGTGVDNIDVKAASARGALVMNTPGANATAAAEHTIAMMLALARHIPQATQSMRE 125
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
GRWD+ + G+EL Q ++G VA R + M+++G DP+
Sbjct: 126 GRWDKKRFMGTELFHQTLGIIGLGKIGSIVADRALSMKMDVLGHDPY 172
Score = 36.7 bits (81), Expect = 0.55
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 241
VLI DG+ +L A GI + EE+ +P++DA++VRS T++T E+++
Sbjct: 3 VLICDGMHEVGLSILRAAEGIDVDVPDQPGAEEIKAMLPDYDAVIVRSRTRITAELIE 60
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 100 bits (239), Expect = 4e-20
Identities = 54/143 (37%), Positives = 80/143 (55%)
Frame = +1
Query: 148 QDLQGRTSYGDTQPRRSGCAFSNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVG 327
+DL+ + + D RSG + + GR KVVGRAG G+DN+D+ +A + G
Sbjct: 114 EDLKKKVAESDALIVRSGTKVTREVFEAAKGR---LKVVGRAGVGIDNVDLQAATEHGCL 170
Query: 328 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGQDPRHPWPW 507
V+NAP AN ++A E L+ +AR+V A ++KAG+W+R+ Y G L G+
Sbjct: 171 VVNAPTANTVAAAEHGIALLASMARNVAQADASIKAGKWERSKYVGVSLVGKTLAVMGFG 230
Query: 508 RVGREVATRMYAFGMNIIGFDPF 576
+VG EVA R GM +I DP+
Sbjct: 231 KVGTEVARRAKGLGMTVISHDPY 253
Score = 40.3 bits (90), Expect = 0.044
Identities = 24/67 (35%), Positives = 38/67 (56%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 250
+L+ + +G LL +G + +S E+L ++ DAL+VRS T+VT+EV +A
Sbjct: 85 ILVTEKLGEAGVNLLREFGDVDCSY-DLSPEDLKKKVAESDALIVRSGTKVTREVFEA-A 142
Query: 251 KRRWSVV 271
K R VV
Sbjct: 143 KGRLKVV 149
>UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2;
Planctomycetaceae|Rep: Phosphoglycerate dehydrogenase -
Rhodopirellula baltica
Length = 540
Score = 99.5 bits (237), Expect = 7e-20
Identities = 53/145 (36%), Positives = 85/145 (58%)
Frame = +1
Query: 142 QGQDLQGRTSYGDTQPRRSGCAFSNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKG 321
+G++L+ + D RSG + S + G R +V RAG G DNID +A ++G
Sbjct: 33 KGEELRQSLNEFDAAILRSGVTITPESLE---GNTRLRALV-RAGVGTDNIDKPAATRRG 88
Query: 322 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGQDPRHPW 501
+ V+N P N +S E T ++L ++R++ A+ +L GRWDR + G+++AG+
Sbjct: 89 IVVMNTPAGNTVSTAEHTFAMLLAMSRNIAAANQSLVEGRWDRKKFMGTQVAGKTLGIVG 148
Query: 502 PWRVGREVATRMYAFGMNIIGFDPF 576
R+GREVA+R AF M+++ FDPF
Sbjct: 149 MGRIGREVASRAQAFDMDVVAFDPF 173
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 98.7 bits (235), Expect = 1e-19
Identities = 47/109 (43%), Positives = 71/109 (65%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ KVVGRAG GVDN+DV++A ++GV V+N P N ++ ELT T +L +R V A+ ++
Sbjct: 64 QLKVVGRAGVGVDNVDVEAATERGVVVMNTPAGNTIATAELTFTHILCGSRPVSQAAASM 123
Query: 430 KAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ G+WDR ++G EL + R+G EVA R AFGM ++ +DP+
Sbjct: 124 REGKWDRKSFSGVELFKKTLGVIGMGRIGGEVARRAVAFGMKVLAYDPY 172
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 97.5 bits (232), Expect = 3e-19
Identities = 48/112 (42%), Positives = 68/112 (60%)
Frame = +1
Query: 241 RRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 420
+ + K + RAG GVDNIDV +A KKG+ V+N P N +S E T L+ L+R V A
Sbjct: 69 KSEKLKAICRAGVGVDNIDVPAATKKGIVVMNTPAGNIISTAEHTIALLCSLSRFVPQAC 128
Query: 421 TALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
++K G+W++ +TG +L G+ RVGR+VA R A M +IG+DPF
Sbjct: 129 ASVKEGKWEKKKFTGQQLTGKTFGIIGLGRVGRQVAKRAAALEMKVIGYDPF 180
Score = 35.5 bits (78), Expect = 1.3
Identities = 21/61 (34%), Positives = 30/61 (49%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 250
VLI D + C E+L G+ K + EL I D ++VRS T++T VL+
Sbjct: 12 VLIADDLPDVCNEILQNAGVEVLKKTGLKPPELDAVIKMCDGVIVRSNTKLTAPVLEKSE 71
Query: 251 K 253
K
Sbjct: 72 K 72
>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
- Aquifex aeolicus
Length = 533
Score = 96.7 bits (230), Expect = 5e-19
Identities = 47/112 (41%), Positives = 68/112 (60%)
Frame = +1
Query: 241 RRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 420
R + KVVGRAG GVDN+D++ A K+G+ V+N PGAN + A ELT ML + R+ A
Sbjct: 62 RAEKLKVVGRAGVGVDNVDIEEATKRGILVVNTPGANTIGATELTMMHMLTIMRNGHKAH 121
Query: 421 TALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
++ +WDR + G EL G+ +G +VA R AFGM ++ +DP+
Sbjct: 122 ESMLNYKWDRKKFMGEELYGRILGIIGLGNIGSQVAIRAKAFGMKVMAYDPY 173
Score = 39.1 bits (87), Expect = 0.10
Identities = 25/62 (40%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 247
VLI D + + ELL + + IS EELL I + DA++ RS T VTKE+L+
Sbjct: 4 VLITDPIAPEGIELLQKDPEVEVYNEPDISYEELLEIIKDFDAIITRSRTPVTKELLERA 63
Query: 248 VK 253
K
Sbjct: 64 EK 65
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 96.7 bits (230), Expect = 5e-19
Identities = 44/106 (41%), Positives = 71/106 (66%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+VVGRAG GVDNID+++A ++G+ V+NAP +N+++ ELT L+L LARH+ A +++ A
Sbjct: 65 RVVGRAGTGVDNIDLEAATRQGIMVVNAPASNSVAVAELTIALILSLARHIPQAHSSVVA 124
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G+W+R + G E+ + R+G EVA R M+++ +DP
Sbjct: 125 GKWERNRFMGFEVRNKTLGLVGLGRIGAEVARRARGLEMHVVAYDP 170
Score = 41.1 bits (92), Expect = 0.025
Identities = 19/39 (48%), Positives = 27/39 (69%)
Frame = +2
Query: 143 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKRR 259
+ + K L+ +P +DAL+VRSAT+VT EVL AG + R
Sbjct: 27 RTDLDKAGLIAILPEYDALIVRSATRVTAEVLAAGTRLR 65
>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 316
Score = 96.3 bits (229), Expect = 6e-19
Identities = 51/118 (43%), Positives = 68/118 (57%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ + E K++ RAGAG+DN+D + A +KG+ V P AN+LS ELT LML L R
Sbjct: 56 DRELIDAAPELKIIARAGAGLDNVDTEYAHEKGIVVCFTPDANSLSVAELTIGLMLALMR 115
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ A G W+R +TG+EL G+ R+G ATR AFGMNI+ DPF
Sbjct: 116 KIPEARQDTLTGGWNRLKFTGTELYGKSFGLIGLGRIGSFTATRAKAFGMNILAADPF 173
>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
Predicted dehydrogenase related to phosphoglycerate
dehydrogenase - Methanopyrus kandleri
Length = 522
Score = 95.9 bits (228), Expect = 8e-19
Identities = 46/110 (41%), Positives = 70/110 (63%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
+ KV+ RAG GVDNIDV +A ++G+ V+NAP ++++S E T L+L LAR + A +
Sbjct: 62 KNLKVIARAGVGVDNIDVKAATERGIIVVNAPESSSISVAEHTMGLILALARKIPQADRS 121
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
++ G WDR + G ELAG+ R+G++VA R AF M + +DP+
Sbjct: 122 VRRGEWDRKRFMGVELAGKTLGLIGLGRIGQQVAKRAKAFEMEVTAYDPY 171
>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Bacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 304
Score = 94.7 bits (225), Expect = 2e-18
Identities = 45/106 (42%), Positives = 66/106 (62%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KVVGRAG G+DN+DV +A KKGV V+NAP NA +A E ++M+ L R++ A+ ++KA
Sbjct: 65 KVVGRAGIGLDNVDVPAASKKGVVVMNAPDGNATTAAEHAVSMMMALTRNIPQATASMKA 124
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G+W++ + G E+ + R+GR A R M +I FDP
Sbjct: 125 GKWEKKKFQGHEVTAKVAGVVGIGRIGRIFAERAMGLRMKVIAFDP 170
Score = 45.2 bits (102), Expect = 0.002
Identities = 22/58 (37%), Positives = 36/58 (62%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
VLI D + +++ G+ + +S EEL+ IP +D LV+RSA++VT E+L+A
Sbjct: 3 VLISDNLAPVGEKIMRDAGLEVDVRTGLSPEELVKIIPAYDGLVIRSASKVTAEILEA 60
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 93.9 bits (223), Expect = 3e-18
Identities = 48/118 (40%), Positives = 73/118 (61%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ + + + KV+GRAG GVDNIDV++A ++G+ V+N P N ++A ELT LML +AR
Sbjct: 53 DRELIEKGEKLKVIGRAGNGVDNIDVEAATQRGILVVNTPAGNTIAAAELTIGLMLAIAR 112
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
++ A A G + R + G EL G+ R+G VA+R+ AF M +I +DP+
Sbjct: 113 NIPQAYHAALNGDFRRDRFKGVELNGKTVGIIGLGRIGSLVASRLAAFNMRVIAYDPY 170
Score = 44.0 bits (99), Expect = 0.004
Identities = 21/61 (34%), Positives = 37/61 (60%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 250
+++ + + + L Y K IS+EELL I ++DA++VRSAT+V +E+++ G
Sbjct: 3 IIVTEKISENGIDYLKKYA-DVDVKTNISREELLEVIKDYDAIIVRSATKVDRELIEKGE 61
Query: 251 K 253
K
Sbjct: 62 K 62
>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 528
Score = 93.9 bits (223), Expect = 3e-18
Identities = 47/107 (43%), Positives = 66/107 (61%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K++GRAG GVDNID+++A + GV V+NAP N SA E T +++ L+R++ A ALK
Sbjct: 68 KIIGRAGVGVDNIDLEAATENGVIVVNAPNGNTNSAAEHTMAMIMALSRNIPQAYHALKQ 127
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+WDR + G EL + R+G EVA R MN+I +DPF
Sbjct: 128 KQWDRKRFVGVELKQKTLGIVGLGRIGAEVAARAKGQRMNVIAYDPF 174
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 93.9 bits (223), Expect = 3e-18
Identities = 54/152 (35%), Positives = 79/152 (51%)
Frame = +1
Query: 148 QDLQGRTSYGDTQPRRSGCAFSNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVG 327
++L + S D RSG S + GR KVVGRAG G+DN+D+ +A + G
Sbjct: 143 EELCTKISLCDALIVRSGTKVSREVFEASSGR---LKVVGRAGVGIDNVDLAAATEHGCL 199
Query: 328 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGQDPRHPWPW 507
V+NAP AN ++A E L+ +AR+V A ++K+G+W R Y G L G+
Sbjct: 200 VVNAPTANTVAAAEHGIALLTAMARNVAQADASVKSGKWQRNKYVGVSLVGKTLAVMGFG 259
Query: 508 RVGREVATRMYAFGMNIIGFDPFRVC*SVRPV 603
+VG EV R GM++I DP+ R +
Sbjct: 260 KVGSEVTRRAKGLGMHVIAHDPYAAADRARAI 291
Score = 38.3 bits (85), Expect = 0.18
Identities = 23/63 (36%), Positives = 36/63 (57%)
Frame = +2
Query: 68 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 247
+VL+ + +GA +LL + +S EEL +I DAL+VRS T+V++EV +A
Sbjct: 113 TVLVAEKLGAAGLDLLKDFANVDCAY-NLSPEELCTKISLCDALIVRSGTKVSREVFEAS 171
Query: 248 VKR 256
R
Sbjct: 172 SGR 174
>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 541
Score = 93.5 bits (222), Expect = 4e-18
Identities = 45/107 (42%), Positives = 64/107 (59%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K + RAG GVDNID +A ++G+ V+N P N S E T LM+ LAR++ PA +K
Sbjct: 67 KAIVRAGVGVDNIDRAAATREGIVVMNTPAGNTTSTAEQTIALMMALARNIGPAYATMKE 126
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G+W+R TG+++AG+ R+G VA R M +IG+DPF
Sbjct: 127 GKWERKKLTGTQVAGKTLAIIGLGRIGLSVAHRAQGLEMKVIGYDPF 173
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 93.5 bits (222), Expect = 4e-18
Identities = 44/107 (41%), Positives = 69/107 (64%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K+V RAG G+DN+DVD+A +GV V+NAP +N SA E L+L +R + A +L+A
Sbjct: 67 KIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRA 126
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
W R+ ++G+E+ G+ R+G+ VA R+ AFG ++I +DP+
Sbjct: 127 HIWKRSSFSGTEIFGKTVGVVGLGRIGQLVAARIAAFGAHVIAYDPY 173
Score = 33.1 bits (72), Expect = 6.7
Identities = 17/32 (53%), Positives = 21/32 (65%)
Frame = +2
Query: 158 KEELLMEIPNHDALVVRSATQVTKEVLDAGVK 253
+ +LL +P DAL+VRSAT V EVL A K
Sbjct: 34 RTKLLAAVPEADALLVRSATTVDAEVLAAAPK 65
>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 532
Score = 93.1 bits (221), Expect = 6e-18
Identities = 45/117 (38%), Positives = 71/117 (60%)
Frame = +1
Query: 226 QRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARH 405
Q+ + + KV+ RAG GVDNID+D+A +G+ VINAP N +SA E + ++L +AR+
Sbjct: 58 QQVIEKASNLKVIARAGVGVDNIDIDAATLQGILVINAPDGNTISATEHSVAMILAMARN 117
Query: 406 VVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ A +LK W+R + G EL + R+G VA R+ +FGM ++ +DP+
Sbjct: 118 IPQAHASLKNKEWNRKAFKGVELYQKTLGVIGAGRIGIGVAQRLQSFGMKVLAYDPY 174
Score = 33.9 bits (74), Expect = 3.9
Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
Frame = +2
Query: 68 SVLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 241
++L+ D + + LLN K + ++ LL I +++ L+VRS TQVT++V++
Sbjct: 4 NILVSDPISTDGLQSLLNHSDFNVDIKTDLDEQSLLDIIGDYEGLIVRSQTQVTQQVIE 62
>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 316
Score = 92.3 bits (219), Expect = 1e-17
Identities = 48/107 (44%), Positives = 69/107 (64%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+ + G GVDNID+D+A +G+ V+ APG+N+ + ELT LM+ AR + A TA+ A
Sbjct: 72 RVIAKHGVGVDNIDLDAARARGIPVVFAPGSNSRAVAELTFGLMIAAARRIAAAHTAVVA 131
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G W + LY G ELAG+ R+GR +A AFGM ++G+DPF
Sbjct: 132 GDWPK-LY-GPELAGRTLGVIGFGRIGRLLAGYAQAFGMTVVGYDPF 176
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 92.3 bits (219), Expect = 1e-17
Identities = 41/107 (38%), Positives = 70/107 (65%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+GRAGAG+DN+D+++A ++G+ V+N PG N ++ E T +L++ +AR + A+ + KA
Sbjct: 69 KVIGRAGAGLDNVDLEAATERGIVVMNTPGGNTVTTAEHTMSLLMSMARRIPQANASNKA 128
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G+W+++ + G EL + ++G+ VA MNII FDP+
Sbjct: 129 GKWEKSKFMGVELFQKTLGIVGMGKIGQHVAQIARGIAMNIIAFDPY 175
Score = 46.8 bits (106), Expect = 5e-04
Identities = 24/63 (38%), Positives = 35/63 (55%)
Frame = +2
Query: 50 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 229
M DI+ +LI D + + G K K+S +EL EI +D LV+RS T+VT+
Sbjct: 1 MSSDIR-ILISDAISEDGVRIFQKAGFHVDMKTKLSPQELAQEISQYDGLVIRSGTKVTR 59
Query: 230 EVL 238
E+L
Sbjct: 60 EIL 62
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 91.5 bits (217), Expect = 2e-17
Identities = 43/110 (39%), Positives = 68/110 (61%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
++ KVV RAG GVDN+DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++
Sbjct: 69 KQLKVVARAGVGVDNVDVEEATKLGIVVVNSPSGNIGAAAEHTIALLIAMARNIPEACSS 128
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
LK+G+W+R+ + G E+ G+ +VG VA GMN+ DP+
Sbjct: 129 LKSGKWERSKFVGVEVKGKTLSIIGLGKVGLTVARLAKGLGMNVNALDPY 178
Score = 33.9 bits (74), Expect = 3.9
Identities = 21/58 (36%), Positives = 32/58 (55%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTGNLLRA 67
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 91.1 bits (216), Expect = 2e-17
Identities = 41/114 (35%), Positives = 68/114 (59%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ ++ KVVGRAG GVDN+D+ +A ++G+ V+N P N+++ E LM +AR +
Sbjct: 67 IAAAKKLKVVGRAGIGVDNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFAVARQLPE 126
Query: 415 ASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
A T+ +AG+W++ + G E+ G+ +G VATR M+++ FDPF
Sbjct: 127 ADTSTRAGKWEKNRFMGVEITGKTLGVVGCGNIGSIVATRGIGLKMHVVAFDPF 180
>UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3;
Alphaproteobacteria|Rep: Phosphoglycerate dehydrogenase
- Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 354
Score = 91.1 bits (216), Expect = 2e-17
Identities = 42/107 (39%), Positives = 65/107 (60%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+ + G GVDNIDVD+A ++ + V+ A GANALS E TL+ + + +VP + ++A
Sbjct: 95 RVLSKHGVGVDNIDVDAASRREIPVVVAAGANALSVAEHAITLLFAVVKRIVPLDSGIRA 154
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
GRW++A Y+G ELAG + R+ A FG+ + +DPF
Sbjct: 155 GRWEKAGYSGKELAGMIIGLVGFGAIARQTAVFARGFGLKVQAYDPF 201
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 90.6 bits (215), Expect = 3e-17
Identities = 44/107 (41%), Positives = 65/107 (60%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K +GRAG GVDNID+++A K+G+ V NAP +N ++A E T LML +AR + A +L+
Sbjct: 64 KAIGRAGIGVDNIDIEAATKRGILVANAPESNTVAAAEHTLGLMLAVARRIPAADASLRR 123
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G W+RA + G E+A + VG VA GM ++ +DP+
Sbjct: 124 GEWNRAAFKGVEVAEKTLGLVGLGHVGSIVARGALGMGMRVLAYDPY 170
Score = 36.7 bits (81), Expect = 0.55
Identities = 22/58 (37%), Positives = 32/58 (55%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
VL+ + + + ELL +S ELL I +D L+VRSAT+VT EV++A
Sbjct: 3 VLVTEKLAERGVELLRRE-FEVDVLLGLSPGELLERIGEYDGLIVRSATKVTAEVIEA 59
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 90.6 bits (215), Expect = 3e-17
Identities = 40/109 (36%), Positives = 68/109 (62%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ K++GRAG GVDNIDV +A ++G+ V+N+P N ++A E +M+ LARH+ A+ ++
Sbjct: 91 QLKIIGRAGVGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSV 150
Query: 430 KAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
K +W+R + G+E+ + ++G VA A GM ++ +DPF
Sbjct: 151 KESKWERKQFIGTEVYKKTLGVVGLGKIGSHVAGVAKAMGMKLLAYDPF 199
Score = 38.7 bits (86), Expect = 0.14
Identities = 18/59 (30%), Positives = 36/59 (61%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 247
VL+ D + ++L K +S+ E++ +P +DA+++RSAT+VT++++ AG
Sbjct: 32 VLVSDSIDQVGIDILKQVA-QVDVKTGLSEAEIIDIVPEYDAIMLRSATKVTEKIIQAG 89
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 90.2 bits (214), Expect = 4e-17
Identities = 44/106 (41%), Positives = 65/106 (61%)
Frame = +1
Query: 259 VVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG 438
+VGRAG GVDNID+D+A + GV V NAP N +A E T + AR + A L+ G
Sbjct: 70 IVGRAGIGVDNIDIDAATEHGVIVANAPEGNVRAAAEHTVAMTFAGARSIPQAHARLRTG 129
Query: 439 RWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
W ++ Y G+E+ G+ RVG+EVA R+ + GM+++ +DP+
Sbjct: 130 EWAKSEYLGTEVNGKTLGVVGLGRVGQEVAKRLESLGMDLVAYDPY 175
Score = 36.7 bits (81), Expect = 0.55
Identities = 23/58 (39%), Positives = 30/58 (51%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
VL+ D + E L A G + T I E LL I + +ALVVRS T V + V +A
Sbjct: 7 VLVTDPIDDAGLERLRAAGHSVETAYDIGDEALLNTITDVNALVVRSGTDVNEAVFEA 64
>UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase;
n=4; Amniota|Rep: 3-phosphoglycerate dehydrogenase -
Rattus norvegicus
Length = 316
Score = 88.6 bits (210), Expect = 1e-16
Identities = 44/106 (41%), Positives = 67/106 (63%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
++VGRAG G+DN+++++A K + V+N P +LSA ELTC +++ L R + P
Sbjct: 65 QLVGRAGTGMDNVNLEAAMTKSILVMNTPNGKSLSASELTCGMIVCLTRQIPP------- 117
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G+WD+ + G+EL G+ R+GREV T+M AF M +GFDP
Sbjct: 118 GKWDQEEFMGTELNGKTLGILGLGRIGREVTTQMQAFRMKAVGFDP 163
Score = 33.5 bits (73), Expect = 5.1
Identities = 20/60 (33%), Positives = 31/60 (51%)
Frame = +2
Query: 59 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 238
++ VLI D + C +LL G+ K +SKEEL++EI + + V + T E L
Sbjct: 5 NLHKVLISDILDPGCWKLLKDGGLQVVEKQNLSKEELIVEIQDCETTKVTADVTNTAEKL 64
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 85.4 bits (202), Expect = 1e-15
Identities = 45/105 (42%), Positives = 66/105 (62%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+ RAG+G+DNID+++A +KG+ V+NAP A + EL +M+VLAR + L
Sbjct: 67 KVIARAGSGLDNIDLEAAKEKGIKVVNAPDALKNAVAELVIGMMVVLARRAHYSYRKLLE 126
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
G W++ + G ELAG+ R+GREVA + A GMN+I +D
Sbjct: 127 GEWEKVM--GFELAGKTLGVVGFGRIGREVAKKAKALGMNVIAYD 169
>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 666
Score = 85.0 bits (201), Expect = 2e-15
Identities = 56/154 (36%), Positives = 78/154 (50%), Gaps = 12/154 (7%)
Frame = +1
Query: 151 DLQGRTSYGDTQPRRSGCAFSNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGV 330
+L + + D RSG + + G GR R VVGRAG G+DN+D+ +A + G V
Sbjct: 110 ELLAKVAQFDALIVRSGTKVTREVLEAGRGRLR---VVGRAGVGIDNVDLQAATEAGCLV 166
Query: 331 INAPGANALSACELTCTLMLVLARHVVPASTALKA------------GRWDRALYTGSEL 474
+NAP AN ++A E L+ +AR+V A ALKA G+W R Y G L
Sbjct: 167 VNAPTANTVAAAEHGIALLASMARNVSQADAALKAVYSRTLTVFTAQGKWQRTKYVGVSL 226
Query: 475 AGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G+ +VG EVA R GM++I DP+
Sbjct: 227 VGKTLAVMGFGKVGSEVARRAKGLGMHVIAHDPY 260
Score = 39.9 bits (89), Expect = 0.059
Identities = 18/32 (56%), Positives = 25/32 (78%)
Frame = +2
Query: 152 ISKEELLMEIPNHDALVVRSATQVTKEVLDAG 247
+S ELL ++ DAL+VRS T+VT+EVL+AG
Sbjct: 106 MSPAELLAKVAQFDALIVRSGTKVTREVLEAG 137
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 84.6 bits (200), Expect = 2e-15
Identities = 48/125 (38%), Positives = 69/125 (55%), Gaps = 5/125 (4%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K++ R G G+DN+DV+ A KKG+ V++AP A + S ELT L+ +AR + + +KA
Sbjct: 65 KILARYGVGLDNVDVEYAVKKGIAVVSAPNAPSQSVAELTIGLLFSVARRIPLLNAKVKA 124
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFRVC*SV-----RP 600
G W + Y G E+AG+ R+GR VA + GMNI+ D V V R
Sbjct: 125 GEWPKGKYIGIEIAGKTMGIVGFGRIGRFVAQMAKSLGMNILASDVIDVSKEVAKIGGRQ 184
Query: 601 VPLHQ 615
VPL +
Sbjct: 185 VPLEE 189
Score = 43.2 bits (97), Expect = 0.006
Identities = 22/60 (36%), Positives = 33/60 (55%)
Frame = +2
Query: 68 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 247
S LIVD V E L GI ISK++L+ I N++ L+ R ++ K+++DAG
Sbjct: 2 SALIVDKVDETLKERLERIGIKVDLAPGISKDDLIKIIKNYNILIFRGRLKIDKDIMDAG 61
>UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase - Strongylocentrotus
purpuratus
Length = 493
Score = 83.4 bits (197), Expect = 5e-15
Identities = 44/94 (46%), Positives = 54/94 (57%)
Frame = +1
Query: 292 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 471
IDV + G PG N LSA E TC ++ L+R + A LKAG+WDR + GSE
Sbjct: 46 IDVYDYLRMAWGSTYTPGGNTLSAAEHTCAMVCCLSRSLPQAHATLKAGKWDRKAFMGSE 105
Query: 472 LAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
L G+ R+GREVA RM +FGM IGFDP
Sbjct: 106 LYGKTLGIVGLGRIGREVAQRMQSFGMTTIGFDP 139
Score = 48.4 bits (110), Expect = 2e-04
Identities = 23/45 (51%), Positives = 27/45 (60%)
Frame = +2
Query: 50 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIP 184
M +K VLI D V +CAE+L GI K+SKEELL EIP
Sbjct: 1 MAFSLKKVLISDSVSPRCAEILRENGIEVDNNTKLSKEELLAEIP 45
>UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 319
Score = 83.4 bits (197), Expect = 5e-15
Identities = 48/117 (41%), Positives = 64/117 (54%), Gaps = 2/117 (1%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K++ R G GVDNIDV +A K G+ V N P AN + EL T ML RH++P A++A
Sbjct: 66 KIIARHGIGVDNIDVKAATKYGIKVTNTPSANINAVAELVLTFMLASTRHLLPIDEAVRA 125
Query: 436 GRWD-RALYTGSELAGQDPRHPWPWRVGREVATR-MYAFGMNIIGFDPFRVC*SVRP 600
G +D R G EL G+ +GR +A + GMNI+ FDP+ SV P
Sbjct: 126 GNFDIRNQLFGYELNGKTVGIIGFGNIGRLIAEKCRLGLGMNIVVFDPYVTAESVEP 182
>UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Comamonadaceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Delftia acidovorans SPH-1
Length = 354
Score = 83.0 bits (196), Expect = 6e-15
Identities = 45/106 (42%), Positives = 60/106 (56%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+ + G GV NIDV +A ++G+ V PGANA S E+T LM AR + L+A
Sbjct: 96 KVISKHGVGVSNIDVAAASQRGIPVYVTPGANAQSVAEMTLGLMFAAARRIAWMDAELRA 155
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
GRW RA G EL+G+ +VG+ VA A GM ++ FDP
Sbjct: 156 GRWSRA-QDGLELSGRTLGLLGFGQVGQRVARVALALGMQVVAFDP 200
>UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Phosphoglycerate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 328
Score = 82.2 bits (194), Expect = 1e-14
Identities = 42/119 (35%), Positives = 70/119 (58%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ + + R+ +++ +G D+ID+++ K GV V++ P AN SA +LT L+L
Sbjct: 56 DEELLKKARQLQLIVTCTSGFDHIDLEATQKWGVTVMHTPTANIESAAQLTWGLVLSCVN 115
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFR 579
++ A +KAG W+R TG ELAG++ R+G VA AFGMN++ +DP++
Sbjct: 116 NIQAAHKMVKAGEWNRDQITGIELAGRNYGIVGLGRIGSRVAELAQAFGMNVVAYDPYQ 174
>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 317
Score = 81.8 bits (193), Expect = 1e-14
Identities = 41/107 (38%), Positives = 60/107 (56%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K + R G GVDNID+D+A + G+ V NAPG NA + ELT L+L R + AL+
Sbjct: 73 KAIARFGVGVDNIDIDAAHRHGIAVTNAPGGNANAVAELTLGLILSAMRRIPYLHDALRG 132
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G WDR + G EL G+ + R++A ++ F + +I +D F
Sbjct: 133 GAWDR--FVGQELIGRRVGLLGFGNIARKIARKLCGFDVEVIAYDKF 177
>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 524
Score = 81.8 bits (193), Expect = 1e-14
Identities = 36/108 (33%), Positives = 63/108 (58%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ K++ RAGAG + ID+ A K + V+N PGAN+ + E +ML +RH++PA +
Sbjct: 63 QLKLIVRAGAGFNTIDIKYARKHDIDVMNTPGANSNAVAEEVVAMMLAASRHLIPADIST 122
Query: 430 KAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
+ G W+++ + G EL G+ +G+ + R+ F M ++G+DP
Sbjct: 123 RKGDWEKSKFMGRELTGKTVGILGLGHIGQLLVKRLAGFEMKVLGYDP 170
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 81.4 bits (192), Expect = 2e-14
Identities = 41/107 (38%), Positives = 62/107 (57%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+GR G GVDNID++ A ++G+ V+NAP +N +SA EL ++ AR + + +A
Sbjct: 82 KVIGRGGVGVDNIDLEYASRRGLLVLNAPESNNVSAAELAVMHLMAAARGLTRSDRKTRA 141
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G WDR + G EL + R+G VA R MN++ +DP+
Sbjct: 142 GEWDRK-FLGLELTDKTLGIVGLGRIGSIVADRAQGLHMNVVAYDPY 187
Score = 39.5 bits (88), Expect = 0.078
Identities = 18/48 (37%), Positives = 29/48 (60%)
Frame = +2
Query: 113 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKR 256
L+ G + + +EE L +P++DAL+ RS T+V +E+LDA R
Sbjct: 33 LDHEGFQIDYQGNLEREETLRRLPDYDALITRSRTKVDRELLDAAGPR 80
>UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Arthrobacter sp.
FB24|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Arthrobacter sp. (strain FB24)
Length = 319
Score = 81.0 bits (191), Expect = 3e-14
Identities = 45/117 (38%), Positives = 67/117 (57%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K + R G GVD+IDV++A + G+ V+ APGAN+ ELT L+L +R + LK+
Sbjct: 85 KAISRNGVGVDSIDVEAAERLGINVLTAPGANSQGVAELTIALILAGSRSIPWHDAQLKS 144
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFRVC*SVRPVP 606
G+W+R G+E++G+ ++GR VAT GM +I FD + V S P P
Sbjct: 145 GQWNRR--PGNEVSGKVLGLIGCGQIGRRVATMALGLGMKVIAFDEYPVT-SFAPSP 198
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 80.6 bits (190), Expect = 3e-14
Identities = 46/142 (32%), Positives = 71/142 (50%)
Frame = +1
Query: 136 HHQGQDLQGRTSYGDTQPRRSGCAFSNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGK 315
H+ +L + D RS + + + K++ RAG GVDNIDV A
Sbjct: 29 HYDKDELLVKIKEFDVLVVRSATKVTKEVIDAATVKGAKLKLIIRAGVGVDNIDVTYARD 88
Query: 316 KGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGQDPRH 495
KG+ V N P A++ S EL M ++R + A+ ++ G+W++ YTG+E+ G+
Sbjct: 89 KGLTVNNTPNASSASVAELAIGHMFAVSRFINTANVTMRQGKWEKKAYTGTEIFGKTLGL 148
Query: 496 PWPWRVGREVATRMYAFGMNII 561
R+ REVA R A GM +I
Sbjct: 149 IGFGRIAREVAKRAEALGMKVI 170
>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
ethanolicus|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 320
Score = 80.6 bits (190), Expect = 3e-14
Identities = 41/110 (37%), Positives = 66/110 (60%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
++ KV+ R G G DN+D+++A KKG+ V N P AN S +L LMLVLAR+++
Sbjct: 71 KKLKVISRYGVGYDNVDLNAAKKKGIVVTNTPNANNNSVADLVIGLMLVLARNLLAVDRI 130
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+K+G W R + G+E+ G+ ++G+ VA R F MN++ +D +
Sbjct: 131 VKSGGWKRIM--GTEIYGKTLGIIGLGKIGKGVAKRAKGFDMNVLCYDVY 178
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 78.2 bits (184), Expect = 2e-13
Identities = 40/109 (36%), Positives = 62/109 (56%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K+V RAG G+DNIDVD+A KG+ V+N PG N+LS EL ++L + RH+ + LK
Sbjct: 66 KIVARAGMGLDNIDVDTAKLKGITVLNTPGQNSLSVAELVIGMVLDIYRHITRGTIGLKN 125
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFRV 582
+W++ G EL+ + VG+ +A + F N + +D F +
Sbjct: 126 EQWEKKQLEGFELSQKTFGIIGFGYVGKNLAQLLKGFQTNTLVYDVFEI 174
Score = 33.9 bits (74), Expect = 3.9
Identities = 16/34 (47%), Positives = 23/34 (67%)
Frame = +2
Query: 140 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 241
T + K+ L +I D L+VRSAT+VTKE+L+
Sbjct: 27 TSEHLEKDVLKDKIKEIDVLIVRSATKVTKEILE 60
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 77.4 bits (182), Expect = 3e-13
Identities = 48/146 (32%), Positives = 72/146 (49%)
Frame = +1
Query: 133 HHHQGQDLQGRTSYGDTQPRRSGCAFSNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAG 312
+H+ +DL+ + D RS + + + K++ R G GVDNIDV A
Sbjct: 28 NHYDIEDLKEKIKKVDCIVIRSATKIRRELIDEAI-KGGKLKLIIRGGVGVDNIDVQYAE 86
Query: 313 KKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGQDPR 492
+ G+ V N P A++ S E+ M LAR + ++ +KAG W + Y G EL G+
Sbjct: 87 QNGIKVRNTPNASSSSVAEIILAHMFSLARFLNQSNITMKAGLWKKKDYVGVELEGKTLG 146
Query: 493 HPWPWRVGREVATRMYAFGMNIIGFD 570
R+G E+A + A GM II FD
Sbjct: 147 IIGMGRIGSELAKKCTALGMKIIYFD 172
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 77.4 bits (182), Expect = 3e-13
Identities = 43/105 (40%), Positives = 58/105 (55%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K++ + G G + IDV +A G+ V PGAN +S EL LML +ARH+ ++
Sbjct: 72 KIIAKHGVGYNTIDVAAAAAYGIPVTITPGANNISVAELAIGLMLAVARHIPQMDGIVRR 131
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
G W R TGSEL G+ +G EVA R +AFGM II +D
Sbjct: 132 GGWSR--MTGSELYGKVLGIIGMGSIGCEVAKRAHAFGMKIIAYD 174
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 77.0 bits (181), Expect = 4e-13
Identities = 37/106 (34%), Positives = 60/106 (56%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K V RAG G+DN+D+ +A K GV V+N P N ++ E T +M+ L R++ + +L++
Sbjct: 69 KAVARAGIGLDNVDIPAATKHGVAVMNTPEGNVVTTAEHTIAMMMALTRNIPQGTLSLRS 128
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G+W++ G E+ + ++G VA R MN+I FDP
Sbjct: 129 GQWEKKKLQGREVFNKTLGVIGFGKIGSIVADRARQLKMNVIVFDP 174
Score = 46.4 bits (105), Expect = 7e-04
Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
Frame = +2
Query: 71 VLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 247
VL+ D + A + L N G A K + EEL I +DAL++RSAT+VT ++L+AG
Sbjct: 5 VLVSDTIDASGVSRLENESGFAVDVKTGLPPEELKSIIGQYDALIIRSATKVTADILEAG 64
Query: 248 VKR 256
+
Sbjct: 65 APK 67
>UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Sinorhizobium medicae
WSM419|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Sinorhizobium medicae WSM419
Length = 328
Score = 76.2 bits (179), Expect = 7e-13
Identities = 40/106 (37%), Positives = 61/106 (57%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+ R G G +N+D++SA ++GV V+ A GAN S EL L L +AR + +++A
Sbjct: 69 RVISRHGVGYNNVDIESATRRGVPVLIADGANGKSVAELAVGLALSVARKITTQDASIRA 128
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
+W+R+ Y G + AG+ +GR VA + A M II FDP
Sbjct: 129 RQWNRSAY-GLQFAGKTAGIVAFGAIGRRVAEILRAMDMRIIAFDP 173
>UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Bradyrhizobium sp. ORS278|Rep:
Putative D-3-phosphoglycerate dehydrogenase -
Bradyrhizobium sp. (strain ORS278)
Length = 335
Score = 76.2 bits (179), Expect = 7e-13
Identities = 38/118 (32%), Positives = 62/118 (52%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D + +G ++ K + + G G DNIDV++A ++G+ V A GAN+ S EL LM +AR
Sbjct: 68 DDQVIGASQKLKAIAKHGVGYDNIDVEAADRRGIPVFVARGANSQSVAELAFALMFAVAR 127
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ +K G WD+A G++L G+ +GR + + M + FDP+
Sbjct: 128 EIPHLDARIKTGHWDKATTKGAQLLGRSLGVIGFGEIGRILVGLVQPLHMEVRIFDPY 185
>UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia multivorans ATCC 17616
Length = 452
Score = 76.2 bits (179), Expect = 7e-13
Identities = 39/107 (36%), Positives = 58/107 (54%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+ + G+G+D ID D+A +G+ V A GANA + E L+L A+ V ++
Sbjct: 210 QVISKHGSGIDVIDQDAAAARGIAVRAAVGANAAAVAEHAWALILACAKSVPQLDMRMRE 269
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G WD+A + EL G+ +GR VA AFGM ++ FDPF
Sbjct: 270 GHWDKATHKSVELDGRTLGLVGLGAIGRRVAAIGVAFGMKVLAFDPF 316
>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus clausii (strain KSM-K16)
Length = 316
Score = 75.4 bits (177), Expect = 1e-12
Identities = 39/109 (35%), Positives = 62/109 (56%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ K++ + G GVDNIDVD+A K GV V N P AN + + +L+L LAR + +
Sbjct: 67 DLKIIAKHGVGVDNIDVDAAKKHGVTVTNVPNANKHAVADFAFSLLLSLARQIPTGNEKT 126
Query: 430 KAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
K G+W +L+ G+++ Q +G+EVA R F M ++ +DP+
Sbjct: 127 KKGKWP-SLF-GADVYQQTLGIIGLGAIGKEVARRASGFSMTVLAYDPY 173
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 75.4 bits (177), Expect = 1e-12
Identities = 39/104 (37%), Positives = 62/104 (59%), Gaps = 1/104 (0%)
Frame = +1
Query: 259 VVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG 438
+V RAGAGV+ IDV +A ++GV V N PG N+++ EL L++ L R + L+AG
Sbjct: 65 LVVRAGAGVNTIDVAAASRRGVYVANCPGQNSIAVAELAIGLVVALDRRIPDNVALLRAG 124
Query: 439 RWDRALYTGSE-LAGQDPRHPWPWRVGREVATRMYAFGMNIIGF 567
+WD+ ++ ++ L G+ +GREVA R A GM ++ +
Sbjct: 125 KWDKKTFSEAQGLYGRTLGVAGVGSIGREVARRAQALGMRVVAW 168
>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
dehydrogenase - Rhizobium sp. (strain NGR234)
Length = 327
Score = 74.9 bits (176), Expect = 2e-12
Identities = 42/109 (38%), Positives = 60/109 (55%), Gaps = 1/109 (0%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
R KV+ R G G D+ID D+A + GVG+ PG NA + + T ++L L R VV A
Sbjct: 69 RNLKVIARVGVGTDSIDHDAAKEFGVGISVTPGMNAETVADQTLAMILGLMRRVVTQDQA 128
Query: 427 LKAGRWDR-ALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
+KAGRWDR T +EL + +G+ V R+ FG+ ++ FD
Sbjct: 129 VKAGRWDRVGEATPTELYRKTVGLIGAGIIGKAVIRRLLGFGVRVLYFD 177
>UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Thermotoga|Rep: Phosphoglycerate dehydrogenase,
putative - Thermotoga maritima
Length = 327
Score = 74.1 bits (174), Expect = 3e-12
Identities = 43/115 (37%), Positives = 65/115 (56%), Gaps = 1/115 (0%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-K 432
K++ + G GVDNID+++A KKG+ V GAN+LS ELT + L+R +V A L
Sbjct: 64 KIIAKHGVGVDNIDLEAATKKGIPVTITAGANSLSVAELTIAFIFALSRGLVWAHNKLFL 123
Query: 433 AGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFRVC*SVR 597
RW+ + G E++G+ +GREV + GMN++ +DP+ SVR
Sbjct: 124 ERRWEGTV--GQEVSGKTLGVVGFGSIGREVVKKAVCLGMNVLVYDPYVSKDSVR 176
>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=6;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 312
Score = 72.9 bits (171), Expect = 7e-12
Identities = 42/107 (39%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+VVGR G G+DNIDV + +G+ VI A GANA S E T +L R S +
Sbjct: 68 RVVGRLGVGLDNIDVAACRDRGIRVIPASGANARSVAEYVVTTAALLLRGAYLGSAEVAG 127
Query: 436 GRWDRA-LYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G+W RA L G E G+ +GR+ A AFGM ++ DP
Sbjct: 128 GKWPRARLSEGREALGKTLGLIGFGDIGRQAAALAQAFGMRVVAHDP 174
>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Arthrobacter
aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Arthrobacter aurescens
(strain TC1)
Length = 329
Score = 72.9 bits (171), Expect = 7e-12
Identities = 37/108 (34%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K++ R G G DN+D+ +A + V V + PG+N+ + E +L+L L R ++PA+ + A
Sbjct: 64 KIIARHGVGTDNVDIPAASEHSVWVTSTPGSNSNAVAEHVFSLLLSLTRRIIPAANRVLA 123
Query: 436 GRW--DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G W R G EL+G+ +G+ VAT FGM ++ DP
Sbjct: 124 GTWAEGRGDLVGFELSGRTLGIVGFGAIGKRVATIANGFGMRVLASDP 171
>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
Length = 522
Score = 72.1 bits (169), Expect = 1e-11
Identities = 37/107 (34%), Positives = 58/107 (54%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K V RAGAG + ID+ A K + V+N PGAN+ + E +M+ AR + + +A
Sbjct: 66 KAVVRAGAGYNTIDIQYARSKDITVMNTPGANSNAVAEEAVGMMISCARFFIEGDRSTRA 125
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G W +A G EL G+ +G+ +A R+ F ++I+ +DPF
Sbjct: 126 GEWKKAQLQGFELTGKTVGIAGFGNIGQLLAKRLSGFEVDILVYDPF 172
>UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase;
n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
Dimethylmenaquinone methyltransferase - Rhodobacter
sphaeroides ATCC 17025
Length = 334
Score = 71.7 bits (168), Expect = 2e-11
Identities = 35/114 (30%), Positives = 59/114 (51%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+G KV+ + G GVDNID+ +A +G+ V+ + G+N+ + E L L+L + + P
Sbjct: 72 IGASPGLKVIVKHGVGVDNIDLAAAEARGIPVLRSMGSNSRAVAEHAIALALMLVKEIQP 131
Query: 415 ASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ A+K G W + + G + G +GRE A A GM ++ DP+
Sbjct: 132 LNAAVKGGAWPKPTFIGKDFQGAMLGLVGYGGIGRETARMAEALGMEVVVHDPY 185
>UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Rhodopseudomonas
palustris BisB18|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 321
Score = 71.3 bits (167), Expect = 2e-11
Identities = 47/134 (35%), Positives = 63/134 (47%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KVV + GAG ++ID+ +A GV V+ A GANA S E LML L + V ++
Sbjct: 71 KVVAKHGAGTNDIDLAAAKALGVPVLAAVGANAHSVAEHAFMLMLALIKDVRNQDAYVRG 130
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFRVC*SVRPVPLHQ 615
G WD+ Y G EL G+ +GR +A + GM I +DPF + P
Sbjct: 131 GGWDKKGYRGRELRGRVLGLVGIGMIGRALAAMVQPIGMTTIAYDPFAPAAAFGPHARRV 190
Query: 616 DGAGGHLASSGSTS 657
D LA S S
Sbjct: 191 DSLDELLAQSDVVS 204
>UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Sinorhizobium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Sinorhizobium medicae WSM419
Length = 310
Score = 71.3 bits (167), Expect = 2e-11
Identities = 39/109 (35%), Positives = 62/109 (56%), Gaps = 1/109 (0%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA-LK 432
+ + R G G+DN+ + ++G+G++ A GANA+ EL+ LML RH +PA TA ++
Sbjct: 72 RAISRNGTGIDNLPLPLLKERGIGILKAEGANAVGVAELSVGLMLAALRH-IPAETAGIR 130
Query: 433 AGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFR 579
AG W R+ G E+A + +G+ VA + A ++I DPFR
Sbjct: 131 AGGWPRS--RGREIAERTVGIIGCGAIGKRVARAVSAMRASVIACDPFR 177
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 71.3 bits (167), Expect = 2e-11
Identities = 39/109 (35%), Positives = 60/109 (55%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K++ RAG G+DNID + A K+ + ++ APGA+ SA ELT L++ AR + + K
Sbjct: 82 KIIARAGIGLDNIDTEEASKRNIKIVYAPGASTDSAAELTIGLLIAAARKLYDSMNMAKG 141
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFRV 582
G + + G ELAG+ R+G +VA A MN+I +D +
Sbjct: 142 GIFKK--IEGIELAGKTIGIVGFGRIGTKVAKVCKALDMNVIAYDVINI 188
Score = 43.6 bits (98), Expect = 0.005
Identities = 26/65 (40%), Positives = 36/65 (55%)
Frame = +2
Query: 56 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 235
+D K VLI D V L G+ K +I++EELL I + L+VRS T+V KE+
Sbjct: 16 LDFK-VLITDPVDQYMIRTLQNNGLIVDYKPEITREELLKIIDQYQVLIVRSRTKVDKEI 74
Query: 236 LDAGV 250
+ GV
Sbjct: 75 IRYGV 79
>UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=27;
Epsilonproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 529
Score = 70.9 bits (166), Expect = 3e-11
Identities = 39/111 (35%), Positives = 59/111 (53%), Gaps = 1/111 (0%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
++ + RAG GVDN+D+ + K+G+ V+N P AN ++A ELT ML R A
Sbjct: 67 KKITAIVRAGVGVDNVDIPGSSKQGIVVMNVPTANTIAAVELTLAHMLSCVRQFPYAHNN 126
Query: 427 LKAGR-WDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
LK R W R + G+EL + +G V R AF M+++ +DP+
Sbjct: 127 LKLDRVWRRQDWYGTELKDKKLGIIGFGNIGSRVGKRAKAFEMDVLAYDPY 177
>UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2;
Lactobacillus|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 392
Score = 70.1 bits (164), Expect = 5e-11
Identities = 41/116 (35%), Positives = 62/116 (53%), Gaps = 9/116 (7%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST---- 423
KV+ RAGAGV+NI +D A G V N PG+NA + EL L+++ +R+++ A+T
Sbjct: 50 KVIVRAGAGVNNIPIDQATANGTAVFNTPGSNANAVKELIIGLLIMASRNLIAATTYSAQ 109
Query: 424 -----ALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ D+ + G EL G+ VG VA + GMN+IG+DP+
Sbjct: 110 HTEADISQRTEHDKTQFNGIELTGKTLAVIGLGHVGALVANAALSLGMNVIGYDPY 165
>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Desulfitobacterium
hafniense|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Desulfitobacterium
hafniense (strain DCB-2)
Length = 320
Score = 70.1 bits (164), Expect = 5e-11
Identities = 38/105 (36%), Positives = 58/105 (55%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K++ + G GVD+ID+ +A +G+ V NAPG NA S +L ML LAR +V A +
Sbjct: 74 KLIIKHGTGVDSIDLKAAAARGITVANAPGTNANSVADLAFGFMLSLARQIVSADKRTRD 133
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
G W + G ++ G+ ++G+ V R F MNI+G+D
Sbjct: 134 GFWGTVM--GKDVYGKTLGVLGLGQIGKGVIRRASGFDMNILGYD 176
>UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: SerA protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 326
Score = 69.3 bits (162), Expect = 8e-11
Identities = 40/121 (33%), Positives = 64/121 (52%), Gaps = 1/121 (0%)
Frame = +1
Query: 217 SSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 396
S D+ + + + KV+GR G GVD++DV +A + G+ V+ APG+N S E LM
Sbjct: 53 SIDRETMLQAKNLKVIGRPGVGVDDVDVKTATELGIPVVIAPGSNTRSVAEHAFALMFAC 112
Query: 397 ARHVVPASTALKAGRWD-RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
A+ +V + ++ G + R+ Y EL + R+G +A A GMN+ +DP
Sbjct: 113 AKDIVRSDNEMRKGNFAIRSSYKAYELNHKTLALIGYGRIGSILAQMSKAIGMNVKVYDP 172
Query: 574 F 576
F
Sbjct: 173 F 173
>UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 336
Score = 69.3 bits (162), Expect = 8e-11
Identities = 39/102 (38%), Positives = 57/102 (55%), Gaps = 1/102 (0%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
++V RAG+G + ID +SA ++GV V N PG NA++ EL LML L R V L+A
Sbjct: 64 RLVIRAGSGTNTIDCESAAERGVHVCNVPGRNAIAVAELAFALMLALDRSVCDNVDDLRA 123
Query: 436 GRWDRALYTGSE-LAGQDPRHPWPWRVGREVATRMYAFGMNI 558
GRWD+ Y+ + + G+ ++G A R AFG +
Sbjct: 124 GRWDKKRYSRARGIHGRRVGVVGLGQIGLAFAERAAAFGATV 165
>UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Pseudomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas fluorescens (strain PfO-1)
Length = 324
Score = 68.9 bits (161), Expect = 1e-10
Identities = 42/108 (38%), Positives = 56/108 (51%), Gaps = 2/108 (1%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
++V R GAG DN+D +A + GV V N PGAN S E L+L ++R V A+ +
Sbjct: 64 RIVARHGAGYDNVDYKAAAELGVWVTNTPGANRRSVVEHVFALLLGISRKVQLATDQTRN 123
Query: 436 GRW--DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
W DR TG EL G+ +GR VA AFGM ++ DP
Sbjct: 124 NIWAQDRLSLTGIELEGRTLGLIGFGDIGRHVAPVAEAFGMKVLATDP 171
>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Lactate dehydrogenase related enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 314
Score = 68.9 bits (161), Expect = 1e-10
Identities = 34/108 (31%), Positives = 62/108 (57%), Gaps = 1/108 (0%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+ R G G D +DVD+A ++G+ V+N P A + S E + +L +++++ S A+
Sbjct: 66 KVIARNGVGYDAVDVDAATQRGIYVVNTPKALSGSVAETAVSELLAISKNLYQDSKAIHD 125
Query: 436 GRWD-RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
W+ R + G ++ G+ R+G++VA ++ F + +I FDPF
Sbjct: 126 DNWNYRKAHPGRDIEGKTVGILGFGRIGQQVAKKLSGFDVKVIAFDPF 173
>UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20;
Streptococcaceae|Rep: Phosphoglycerate dehydrogenase -
Lactococcus lactis subsp. cremoris (strain SK11)
Length = 398
Score = 68.9 bits (161), Expect = 1e-10
Identities = 40/121 (33%), Positives = 66/121 (54%), Gaps = 11/121 (9%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
+E +GRAGAG +NI ++ KG+ V NAPG NA + EL ++M+ R++ PA+
Sbjct: 51 KELLAIGRAGAGFNNIPIEKCASKGIVVFNAPGGNANAVKELVLSMMIFGTRNLKPANKW 110
Query: 427 LKAGRW-DRAL----------YTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
L + D+A+ ++GSE++G+ +G +VA GM +IG+DP
Sbjct: 111 LTGQKGNDKAIDVAVENGKKAFSGSEISGKTLGVIGLGNIGSKVANDAQRLGMKVIGYDP 170
Query: 574 F 576
+
Sbjct: 171 Y 171
>UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 318
Score = 68.9 bits (161), Expect = 1e-10
Identities = 38/105 (36%), Positives = 58/105 (55%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+ + G G+D IDV A K + V+ PG N + E T L+L L ++++ + + ++
Sbjct: 71 KVISKYGIGLDKIDVAHATSKKIPVLFTPGVNHTTVAEHTFLLLLALEKNILFHTDSTRS 130
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
G W R TG EL + R+G+EVA R AFGM +I +D
Sbjct: 131 GGWKRK--TGHELLAKTIGIVGLGRIGKEVAIRARAFGMEVIAYD 173
>UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2;
Bordetella|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 330
Score = 68.5 bits (160), Expect = 1e-10
Identities = 38/119 (31%), Positives = 60/119 (50%), Gaps = 2/119 (1%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D R + R +V+G G G + ID+ +A + G+ V+N PGANA S EL + + L +
Sbjct: 58 DTRAIEAGRRLRVIGNHGTGTNMIDLAAAERLGIPVVNTPGANARSVAELALAMAMALLK 117
Query: 403 HVVPASTALKAGRWDRALYTG-SELAGQDPRHPWPWRVGREVAT-RMYAFGMNIIGFDP 573
VP A++ G W+ G EL+G ++GR +A + FGM + + P
Sbjct: 118 RTVPLDQAVRQGNWNIRYEAGLRELSGMSLGIVGFGQIGRALAAMAIGGFGMRVHVYSP 176
>UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3;
Crenarchaeota|Rep: Phosphoglycerate dehydrogenase -
Cenarchaeum symbiosum
Length = 310
Score = 68.5 bits (160), Expect = 1e-10
Identities = 36/108 (33%), Positives = 55/108 (50%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
++ K++ R G G+DNID+ +A GV VINA + EL +ML +AR + A
Sbjct: 66 KDCKIIARVGVGLDNIDLAAAESAGVRVINAVEGATTAVSELVLGMMLCMARQIPRADRG 125
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
++ G+W + G+EL G+ +GR + MNIIG D
Sbjct: 126 IRGGKWLKGELGGTELKGKYLGIVGLGNIGRRLGRLARGMNMNIIGHD 173
Score = 40.7 bits (91), Expect = 0.034
Identities = 19/58 (32%), Positives = 32/58 (55%)
Frame = +2
Query: 65 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 238
++VLI D +L G+ + K +I+ EEL E P + ++VRS T +T E++
Sbjct: 5 ETVLICDKADPVLGRILQQNGLRVSYKPEITPEELAAEAPGYSIIIVRSRTTITGEII 62
>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=41; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Bacillus anthracis
Length = 323
Score = 68.1 bits (159), Expect = 2e-10
Identities = 40/111 (36%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K+V GAG DNID AG+KG+ V N P + + ELT L+L AR + T +
Sbjct: 67 KIVANYGAGYDNIDYTYAGEKGIAVTNTPKVSTEATAELTFALLLAAARRIPEGDTLCRT 126
Query: 436 ---GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFR 579
W + G E+ G+ +G+ VA R AFGMNI+ P R
Sbjct: 127 TGFNGWAPLFFLGREVHGKTIGIIGLGEIGKAVAKRAKAFGMNILYTGPNR 177
Score = 32.7 bits (71), Expect = 8.9
Identities = 19/47 (40%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Frame = +2
Query: 107 ELLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
ELL + + K + IS +EL + + DAL+ +T+VTKEV+DA
Sbjct: 16 ELLKDHDVEMYDKEELISLDELTERVKDKDALLSLLSTKVTKEVIDA 62
>UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermoanaerobacter
ethanolicus X514|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 324
Score = 68.1 bits (159), Expect = 2e-10
Identities = 38/109 (34%), Positives = 60/109 (55%), Gaps = 2/109 (1%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K++ R GAGVDNIDV++A +KG+ V N P N LS E T ++L L++ + A+++
Sbjct: 65 KIISRTGAGVDNIDVNAATEKGILVCNLPAVNNLSVAEHTIAMILNLSKQLSLMDKAVRS 124
Query: 436 GRWD-RALYTGSELAGQDPRHPWPWRVGREVATRMY-AFGMNIIGFDPF 576
G W R E+ G+ +G VA + + GM I+ +DP+
Sbjct: 125 GNWGARNSNISVEIEGKVLGIVGMGNIGSLVAKKCHDGLGMKIVAYDPY 173
>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
reductase - Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 68.1 bits (159), Expect = 2e-10
Identities = 35/123 (28%), Positives = 67/123 (54%), Gaps = 3/123 (2%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ + ++AK++ G +NID+++A ++G+ V N PG + ++ L+L +AR
Sbjct: 56 DKEFIYSLKKAKIIANYAVGYNNIDIEAAKERGIYVTNTPGVLTEATADIAFALILAVAR 115
Query: 403 HVVPASTALKAGR---WDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
+V + ++ G+ W L+ G +L G+ R+G+ VA R FGMNI+ ++
Sbjct: 116 RIVESDKFVREGKFVGWKPKLFLGYDLYGKTLGVIGMGRIGQAVARRALGFGMNIVYYNR 175
Query: 574 FRV 582
R+
Sbjct: 176 NRL 178
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 67.7 bits (158), Expect = 3e-10
Identities = 37/108 (34%), Positives = 60/108 (55%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
+ K++ + G GVD+IDV +A + G+ V NAPG N+ +L L+ +LAR + A+T
Sbjct: 71 KRLKIIAKHGVGVDSIDVKTANQLGIVVTNAPGTNSEEVADLAFGLLHMLARGLYQANTD 130
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
K G+W + + G L+ + +G VA R + MNI+G+D
Sbjct: 131 TKNGKWIKPV--GISLSKKTIGIIGVGTIGTAVAKRATGYDMNILGYD 176
>UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Phosphoglycerate dehydrogenase
- Rhodococcus sp. (strain RHA1)
Length = 325
Score = 67.7 bits (158), Expect = 3e-10
Identities = 40/107 (37%), Positives = 53/107 (49%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+ RAG G+DNIDV A + GV V+ GANA+S E T + L R V +
Sbjct: 73 RVIARAGVGLDNIDVKCANEAGVVVVAPLGANAISVAEHTIGMALAAVRRTVELDADCRR 132
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G W+R G EL G GR A + GM+I+ +DPF
Sbjct: 133 GGWERT--PGRELHGGVWGLLGAGATGRACARLARSLGMSIVAYDPF 177
>UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Roseiflexus sp.
RS-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Roseiflexus sp. RS-1
Length = 323
Score = 67.7 bits (158), Expect = 3e-10
Identities = 38/107 (35%), Positives = 55/107 (51%), Gaps = 1/107 (0%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+ + R G GVDNID+ +A K+G+ VIN P S E L+L LA+ VV + L+
Sbjct: 70 RAICRPGIGVDNIDIAAATKRGILVINTPDGPTESTAEHAVALLLALAKQVVASDRVLRT 129
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVA-TRMYAFGMNIIGFDP 573
W A G E+ G+ R+GR VA GM+++ +DP
Sbjct: 130 EGWRAARLRGIEVRGKTLGIVGLGRIGRRVAQICRQGLGMHVVAYDP 176
>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative D-3- phosphoglycerate
dehydrogenase; n=1; Propionibacterium acnes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase, putative
D-3- phosphoglycerate dehydrogenase - Propionibacterium
acnes
Length = 321
Score = 66.9 bits (156), Expect = 4e-10
Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 3/122 (2%)
Frame = +1
Query: 205 AFSNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTL 384
+ S+ D +G+ + KV+G+ AG +NID+D+A + GV V + PG + +L TL
Sbjct: 49 SLSDPLDAEMIGQGKNLKVIGQCAAGFNNIDLDAAKQAGVVVTSTPGVLHEATADLAFTL 108
Query: 385 MLVLARHVVPASTALKAG---RWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMN 555
+L + R A ++AG R+D G+ L G ++G +A R AFGMN
Sbjct: 109 LLEVTRRTGEAERWVRAGRAWRYDHTFMLGAGLQGATLGIVGLGQIGEAMARRGAAFGMN 168
Query: 556 II 561
+I
Sbjct: 169 VI 170
>UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=2; Burkholderia|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 312
Score = 66.9 bits (156), Expect = 4e-10
Identities = 37/112 (33%), Positives = 57/112 (50%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D + R ++V GAG +N+DV +A ++G+ V +APG NA + + ++L LAR
Sbjct: 56 DDARMARLPALEIVCAFGAGYENVDVAAAARRGIVVAHAPGTNASTVADHAIGMLLALAR 115
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNI 558
P + A++AGRW + L G R+GR VA R F M +
Sbjct: 116 GYAPLTGAVRAGRWHASRAARPTLTGAALGVIGMGRIGRLVAARAQGFDMTL 167
>UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. SG-1|Rep: Putative uncharacterized protein
- Bacillus sp. SG-1
Length = 322
Score = 66.9 bits (156), Expect = 4e-10
Identities = 39/116 (33%), Positives = 66/116 (56%), Gaps = 2/116 (1%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ + + KV+ R G GVDNID+++A +G+ V NAP AN + E TL+L +R ++
Sbjct: 59 IEKASKLKVIARHGIGVDNIDLEAASDRGILVTNAPFANVNAVAEHVLTLILSGSRQLIQ 118
Query: 415 ASTALKAGRWD-RALYTGSELAGQDPRHPWPWRVGREVATRM-YAFGMNIIGFDPF 576
+AL+ G ++ R G EL G+ +G+ VA + Y GM+++ +DP+
Sbjct: 119 VDSALRNGDFEVRNRKFGIELKGKTLGVVGFGNIGQLVAEKCHYGLGMDVLVYDPY 174
>UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2;
Burkholderiales|Rep: D-3-Phosphoglycerate dehydrogenase
- Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428
/ Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 360
Score = 66.5 bits (155), Expect = 6e-10
Identities = 39/105 (37%), Positives = 54/105 (51%), Gaps = 1/105 (0%)
Frame = +1
Query: 262 VGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR 441
V +G+G D ID+D+ + GV V+N G NA S E+T LML + R + + +L+A
Sbjct: 88 VSSSGSGCDTIDIDACTEAGVAVLNQAGGNADSVAEMTLGLMLAVLRRIAESDRSLRAHN 147
Query: 442 WD-RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
+ R G EL G+ GR VA A GM +IG DP
Sbjct: 148 CESREDLMGHELRGRTLGLVGVGHAGRRVAALGRALGMRVIGCDP 192
>UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pelobacter propionicus
DSM 2379|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pelobacter propionicus
(strain DSM 2379)
Length = 357
Score = 66.5 bits (155), Expect = 6e-10
Identities = 38/116 (32%), Positives = 64/116 (55%)
Frame = +1
Query: 217 SSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 396
S+D G R K++ RAG+G+DN+DV+ A K+GV ++ P +A + E+ ML L
Sbjct: 76 SADLMGCAPR--LKLLVRAGSGMDNLDVEYARKRGVQLVRIPQPSARAVAEMAFAFMLAL 133
Query: 397 ARHVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIG 564
+R ++ A +++ GRW++ ++G L + G VA A+GM +IG
Sbjct: 134 SRRLLEADRSMRNGRWEKHEFSGYLLRDKTLGVVGIGNTGSCVAQMGVAWGMRVIG 189
>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Thermoplasmatales|Rep: D-3-phosphoglycerate
dehydrogenase - Picrophilus torridus
Length = 299
Score = 65.7 bits (153), Expect = 1e-09
Identities = 36/120 (30%), Positives = 60/120 (50%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ + + K++ RAG G D+IDVD A +KG+ ++ APG++ S ELT ++ AR
Sbjct: 55 DRDIIDNAKRLKIIARAGIGTDSIDVDYAQEKGIKIVYAPGSSTESVVELTVAFAVIAAR 114
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFRV 582
++ + D G EL+G+ R+GR +A F + I +D + V
Sbjct: 115 QIIKGVENTRKN--DFTKLKGIELSGKTLGIIGYGRIGRAIANAFSVFNVRSIAYDAYPV 172
Score = 33.5 bits (73), Expect = 5.1
Identities = 17/57 (29%), Positives = 33/57 (57%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 241
+LI D V E L+ I+++ELL +I ++D ++VRS T++ ++++D
Sbjct: 5 ILICDPVDGIMIEKLSK-DFDIDNSPDITRDELLKKIGDYDIIIVRSRTKIDRDIID 60
>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Brevibacterium linens BL2
Length = 314
Score = 65.3 bits (152), Expect = 1e-09
Identities = 36/102 (35%), Positives = 51/102 (50%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+ RAG G DN+D+D+A + G+ V N PG N + EL LML AR + +
Sbjct: 72 KVIARAGVGYDNVDIDAAAELGIRVCNTPGVNHHAVAELALALMLACARRLNTVLAGVDD 131
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
G W R G+EL G+ G+ +A A GM ++
Sbjct: 132 GGWPRE--AGTELRGKSLGVIGYGPSGKAIAALGVALGMRVL 171
>UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n=1;
Oenococcus oeni PSU-1|Rep: Lactate dehydrogenase related
enzyme - Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 311
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/119 (31%), Positives = 64/119 (53%), Gaps = 1/119 (0%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D + + + K++ R G G DN+D AG+ GV V P ANA + E T +L L++
Sbjct: 53 DNQTLTKFTNLKIIARHGVGFDNVDEKFAGEHGVYVTITPMANASTVAETTIAEILDLSK 112
Query: 403 HVVPASTALKAGRWDRAL-YTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
++ S ++ G + L + G +L+ + R+GR+VA + A GM+++ FDPF
Sbjct: 113 NLTKISDEMRQGNFAYKLDHMGFDLSHKKIGVMGYGRIGRQVAEKANALGMDVLIFDPF 171
>UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Flexibacteraceae|Rep: D-3-phosphoglycerate dehydrogenase
- Microscilla marina ATCC 23134
Length = 316
Score = 65.3 bits (152), Expect = 1e-09
Identities = 39/117 (33%), Positives = 61/117 (52%), Gaps = 1/117 (0%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ +GR KV+ RAGAG+D ID+ +A +G+ V+NAP N + E T ++L L
Sbjct: 56 DEDLIGRASRLKVIARAGAGLDKIDLSAANARGIKVLNAPEGNRDAVGEQTIGMLLSLLH 115
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFG-MNIIGFD 570
+V A +K W R G EL + +G+ A R+ +FG ++I +D
Sbjct: 116 NVQRADWEVKNFAWKREANRGVELMDKVVGVIGYGNMGKAFAKRLSSFGCKDVIAYD 172
>UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Phosphoglycerate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 326
Score = 65.3 bits (152), Expect = 1e-09
Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 2/117 (1%)
Frame = +1
Query: 226 QRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARH 405
Q + + + K++ + G GVDNID+ +A G+ V N PG NA S ELT +++ L R
Sbjct: 58 QELIQKAPKLKMIQKTGVGVDNIDLAAAKTLGIPVANTPGGNATSVAELTLGMIINLYRK 117
Query: 406 VVPASTALKAGRWDRALYTGS--ELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
+ K G W + S E+ G+ +GREVA AFG N+I +D
Sbjct: 118 INILDRETKKGNWMSWEFRPSSYEVKGKTHGIIGFGNIGREVARLSQAFGTNVIYYD 174
>UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Metallosphaera sedula
DSM 5348|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Metallosphaera sedula DSM
5348
Length = 324
Score = 65.3 bits (152), Expect = 1e-09
Identities = 35/115 (30%), Positives = 62/115 (53%), Gaps = 5/115 (4%)
Frame = +1
Query: 247 REAKVVGRAGAGVDN--IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 420
R K++ R GAGVD +D+ +A ++ + + PG N+++ ELT L + L R V+P +
Sbjct: 68 RNLKLIARTGAGVDETRVDLKAAKERDIIITYNPGGNSVAVAELTIMLAIALYRKVIPLA 127
Query: 421 TALKAGRWDRAL---YTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
++KAG+W G EL G+ +G+ VA + + ++G+DP+
Sbjct: 128 LSVKAGKWSELKPKDTMGHELEGKAWGILGFGNIGKRVAQLVTSLNCKVLGYDPY 182
>UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep:
Lmo2824 protein - Listeria monocytogenes
Length = 395
Score = 64.9 bits (151), Expect = 2e-09
Identities = 40/117 (34%), Positives = 61/117 (52%), Gaps = 10/117 (8%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK- 432
K V RAGAGV+NI V++ +KG+ V N PGANA + EL + V AR ++ + +K
Sbjct: 51 KAVARAGAGVNNIPVENCSEKGIVVFNTPGANANAVKELVLASLFVSARPILEGTEWVKE 110
Query: 433 ---------AGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ + G+ELAG+ +G VA + GM+++G+DPF
Sbjct: 111 LPAEDDVEQKVEAGKKAFAGTELAGKKLGIIGLGAIGALVANDALSLGMDVVGYDPF 167
>UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 391
Score = 64.9 bits (151), Expect = 2e-09
Identities = 41/115 (35%), Positives = 58/115 (50%), Gaps = 11/115 (9%)
Frame = +1
Query: 262 VGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA-------- 417
+GRAGAG +NI V ++G+ V NAPGANA + EL ML+ AR++VPA
Sbjct: 56 IGRAGAGTNNIPVKKMSERGLPVFNAPGANANAVKELVIAGMLMGARNLVPALKFVESLD 115
Query: 418 ---STALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
KA + + G EL G+ +G +A GMN++G+DP
Sbjct: 116 GTDEAMHKATEAGKKQFAGMELPGRTLGVIGLGAIGSHIAEAAIRLGMNVVGYDP 170
>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
- Pedobacter sp. BAL39
Length = 309
Score = 64.9 bits (151), Expect = 2e-09
Identities = 37/119 (31%), Positives = 61/119 (51%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ + + K + RAGAG+DNID A ++ + +INAP N + E LML L
Sbjct: 57 DRELIDAGTKLKFIARAGAGLDNIDEAVALERNIHLINAPEGNMDAVGEHAVGLMLSLMN 116
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFR 579
+ A ++ G+WDR G EL G+ +G +A ++ FG+ +I +D ++
Sbjct: 117 NFRNADMEIRKGKWDREGNRGYELKGKTVGIIGYGFMGSSLARKLSGFGVQVIAYDKYK 175
>UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep: Phosphoglycerate
dehydrogenase - Cytophaga hutchinsonii (strain ATCC
33406 / NCIMB 9469)
Length = 314
Score = 64.5 bits (150), Expect = 2e-09
Identities = 37/119 (31%), Positives = 61/119 (51%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D++ + + + + RAGAGVDNID + +K + + +A N ++ E T L+L L
Sbjct: 57 DKKIIDSCTKLQFIARAGAGVDNIDKEYLKEKNIALFHASEGNRVAVGEHTLGLILALIN 116
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFR 579
++V + T +K W R G EL +G+E + R+ AFG II +D +R
Sbjct: 117 NIVRSDTEVKDAIWLREENRGYELESLTVGLIGYGNMGKETSKRLAAFGCKIIAYDKYR 175
Score = 40.3 bits (90), Expect = 0.044
Identities = 22/60 (36%), Positives = 34/60 (56%)
Frame = +2
Query: 74 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 253
LIVD V +LL+ IA K SKE + +P ++ LV+RS +V K+++D+ K
Sbjct: 7 LIVDDVDTALFQLLDKAAIAYDYKPDWSKETCIEALPAYEGLVIRSKFRVDKKIIDSCTK 66
>UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 403
Score = 64.1 bits (149), Expect = 3e-09
Identities = 38/115 (33%), Positives = 61/115 (53%), Gaps = 11/115 (9%)
Frame = +1
Query: 262 VGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR 441
+GRAGAG +NI V+ +G+ V N PGANA + EL ML+ +R+++PA ++
Sbjct: 61 IGRAGAGTNNIPVNQMSARGIPVFNTPGANANAVRELVLAGMLMASRNLIPALRFVETLE 120
Query: 442 WD-----------RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
D + ++G EL G+ ++GR+VA GM ++G+DP
Sbjct: 121 GDDQSFNLQVEAGKKQFSGLELPGRTLGVIGLGKIGRQVADIAIKLGMKVLGYDP 175
>UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=3; Nitrosomonadaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 311
Score = 64.1 bits (149), Expect = 3e-09
Identities = 36/106 (33%), Positives = 54/106 (50%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+ R G G+DN+D+++A + + V N P A A + ELT LML R + +++
Sbjct: 73 RVIARCGTGMDNVDLEAARRLNIQVSNTPEAPAQAVAELTLGLMLDCLRQINRIDRSVRQ 132
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G W R+ G LA + +GR VA AFG +I DP
Sbjct: 133 GEWPRS--QGRLLAARTVGIVGLGHIGRRVAKLCQAFGAQVIAHDP 176
>UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE
DEHYDROGENASE SERA2; n=11; Mycobacterium|Rep: POSSIBLE
D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA2 - Mycobacterium
tuberculosis
Length = 326
Score = 64.1 bits (149), Expect = 3e-09
Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
R +VV N+D+ A G+ V++ P NA + E+T L+L +ARH++PA
Sbjct: 72 RGLRVVAATRGDPSNVDIPGATAAGIPVLHTPARNADAVAEMTVALLLAVARHLIPADAD 131
Query: 427 LKAGRWDR------ALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFR 579
+++G R + G+E+AG VGR V R+ G+ +I DP+R
Sbjct: 132 VRSGNIFRDGTIPYQRFRGAEIAGLTAGLVGLGAVGRAVRWRLSGLGLRVIAHDPYR 188
>UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=8; Yersinia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Yersinia pestis (biovar Antiqua strain
Nepal516)
Length = 316
Score = 64.1 bits (149), Expect = 3e-09
Identities = 37/108 (34%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +1
Query: 259 VVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG 438
V+ R G GVDNID+ +A K+G+ + N P + + L LAR + +++G
Sbjct: 68 VIVRYGVGVDNIDLSAARKRGMRICNVPDYGIEEVADHAAAMTLALARKLGRYEAGIRSG 127
Query: 439 RW--DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
RW D+ + L R+ R ATRM FG IIGFDP+
Sbjct: 128 RWEIDQMVDGVRSLRDTTVGLIGLGRIARAYATRMAVFGCRIIGFDPY 175
>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidovorax sp.
JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 339
Score = 64.1 bits (149), Expect = 3e-09
Identities = 35/115 (30%), Positives = 57/115 (49%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
++V AG D+ID+++ K+G+ V + P + S E L+L + RH+ A +
Sbjct: 73 RLVATRSAGFDHIDLEACRKRGIAVCHVPDYGSASVAEHAFALLLGVTRHLTQAHERARQ 132
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFRVC*SVRP 600
G + TG EL G+ R+GR VA FGM+++ +DP + RP
Sbjct: 133 GSFAYRGLTGFELEGRTLGIVGLGRIGRHVARIAVGFGMDVLAYDPAFAASAARP 187
>UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15;
Viridiplantae|Rep: Glycerate dehydrogenase - Cucumis
sativus (Cucumber)
Length = 382
Score = 64.1 bits (149), Expect = 3e-09
Identities = 41/116 (35%), Positives = 57/116 (49%), Gaps = 4/116 (3%)
Frame = +1
Query: 244 RREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 423
R K G +N+DV++A K GV V N PG + EL +L L AR +V A
Sbjct: 84 RAGGKAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLTETTAELAASLSLAAARRIVEADE 143
Query: 424 ALKAGRWD---RALYTGSELAGQDPRHPWPWRVGREVATRMY-AFGMNIIGFDPFR 579
++AGR+D L+ G+ L GQ R+G A M F MN+I FD ++
Sbjct: 144 FMRAGRYDGWLPNLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQ 199
>UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=19; Bacteria|Rep: D-3-phosphoglycerate
dehydrogenase, putative - Bacillus anthracis
Length = 390
Score = 63.7 bits (148), Expect = 4e-09
Identities = 37/119 (31%), Positives = 64/119 (53%), Gaps = 9/119 (7%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
++ K + RAGAGV+NI V+ +KG+ V N PGANA + EL +++ +R+++ +
Sbjct: 49 KDLKAIARAGAGVNNIPVERCTEKGIVVFNTPGANANAVKELIIASLIMSSRNIINGVSW 108
Query: 427 LKAGRWD---------RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
K + + + GSE+AG+ +G VA A GM+++G+DP+
Sbjct: 109 TKNLEGEEVPQLVESGKKQFVGSEIAGKRLGVIGLGAIGALVANDALALGMDVVGYDPY 167
>UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit; n=3;
Rhodobacteraceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit - Roseovarius sp.
HTCC2601
Length = 326
Score = 63.7 bits (148), Expect = 4e-09
Identities = 34/107 (31%), Positives = 55/107 (51%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+ V + G GVDNID+ + + G+ V N P ANA + EL LM +AR + ++ A
Sbjct: 74 RAVIKHGVGVDNIDIPACTEAGLPVCNTPAANADAVAELAVGLMFSMARWIPQGHASVTA 133
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G WDR + G++L G+ +G+ +A GM ++ D +
Sbjct: 134 GGWDRRI--GTQLGGKTLGIVGLGNIGKRLAKLARGLGMQVVATDKY 178
>UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Roseiflexus castenholzii
DSM 13941|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Roseiflexus castenholzii DSM
13941
Length = 345
Score = 63.7 bits (148), Expect = 4e-09
Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
Frame = +1
Query: 262 VGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR 441
+ R G GVDNID+ +A ++G+ VIN P S E L+L LA+ VV A +
Sbjct: 73 IARPGIGVDNIDLAAATERGILVINTPDGPTESTAEHAVALVLALAKQVVAADHRFRTAG 132
Query: 442 WDRALYTGSELAGQDPRHPWPWRVGREVA-TRMYAFGMNIIGFDP 573
W A G E+ G+ R+GR VA GM + +DP
Sbjct: 133 WSAARLRGVEVRGKTLGVVGLGRIGRRVAQICRQGLGMRVAAYDP 177
>UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein; n=1; Sagittula
stellata E-37|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein - Sagittula stellata
E-37
Length = 320
Score = 63.7 bits (148), Expect = 4e-09
Identities = 35/115 (30%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ R K+V R G G D +DV + +G+ + AN+ S E C L+L + +
Sbjct: 59 IDRADRLKIVSRHGVGYDAVDVAALNARGIALAVCGDANSTSVAEHACMLILAAFKRALR 118
Query: 415 ASTALKAGRWD-RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
A A++ G W R ++ G++ R+G+ AT M FGMNI DP+
Sbjct: 119 ADVAVRRGPWGWRNQLESQDIRGRNLLILGFGRIGQHTATMMSGFGMNIRAHDPY 173
>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
reductase; n=2; Thermus thermophilus|Rep: Glycerate
dehydrogenase/glyoxylate reductase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 338
Score = 63.3 bits (147), Expect = 6e-09
Identities = 36/116 (31%), Positives = 59/116 (50%), Gaps = 3/116 (2%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D + R + KV+ GVD++D+++A ++G+ V + PG + +LT L+L +AR
Sbjct: 83 DAEVMDRAKGLKVIACYSVGVDHVDLEAARERGIRVTHTPGVLTEATADLTLALLLAVAR 142
Query: 403 HVVPASTALKAG---RWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
VV + + G W L G +L G R+G+ VA R AFGM ++
Sbjct: 143 RVVEGAAYARDGLWRAWHPELLLGLDLQGLTLGLVGMGRIGQAVAKRALAFGMRVV 198
>UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putative;
n=1; Blastopirellula marina DSM 3645|Rep:
Phosphoglycerate dehydrogenase, putative -
Blastopirellula marina DSM 3645
Length = 320
Score = 63.3 bits (147), Expect = 6e-09
Identities = 34/110 (30%), Positives = 56/110 (50%)
Frame = +1
Query: 244 RREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 423
R + +VV R G G D+++V +A ++ + V PG S E T ++L + R+V+ +
Sbjct: 63 RTQVRVVSRVGVGYDSVNVPAATEQNIAVCRTPGTLHQSVVEHTIGMILAIYRNVISQNK 122
Query: 424 ALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
++AG WDR G G+ +G+EVA GM +I +DP
Sbjct: 123 QVRAGDWDRT--AGPRAYGKTLGIIGYGVIGKEVAKAAVLLGMQVIAYDP 170
>UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=3; Desulfovibrio|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Desulfovibrio desulfuricans (strain G20)
Length = 305
Score = 62.9 bits (146), Expect = 7e-09
Identities = 37/120 (30%), Positives = 58/120 (48%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+ R G G+DN+D+++A +G+ V N P + ELT L L L R V L++
Sbjct: 71 KVISRCGTGMDNVDMEAARARGIAVRNTPDGPTQAVAELTLGLALDLMRQVSRMDRELRS 130
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFRVC*SVRPVPLHQ 615
G W + + G+ L G+ R+GR VA G+ + DP C +P+ +
Sbjct: 131 GVWKKRM--GNLLGGKRLGIVGMGRIGRAVADIFTPLGVQVAFNDPVSCCGDYPCMPVEE 188
>UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 387
Score = 62.5 bits (145), Expect = 1e-08
Identities = 41/130 (31%), Positives = 64/130 (49%), Gaps = 10/130 (7%)
Frame = +1
Query: 217 SSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 396
S+D G + + R GAGV+NI V+ KKGV V N+PGAN+ + EL ++++
Sbjct: 38 STDLHGYELPEGIRAIARCGAGVNNIPVEEYAKKGVVVFNSPGANSNAVKELVLGMLVLS 97
Query: 397 ARHVVPASTALKAGRWD----------RALYTGSELAGQDPRHPWPWRVGREVATRMYAF 546
+R VV + ++ D + + G EL G+ VG +VA
Sbjct: 98 SRGVVQSMNWVRDNADDPEIQVDAEKAKKAFVGRELKGKRIGVIGLGNVGSKVANACVDL 157
Query: 547 GMNIIGFDPF 576
GM++ G+DPF
Sbjct: 158 GMDVYGYDPF 167
>UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=11; Bacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Coxiella burnetii
Length = 388
Score = 62.1 bits (144), Expect = 1e-08
Identities = 41/117 (35%), Positives = 59/117 (50%), Gaps = 11/117 (9%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA------ 417
+V+GRAG GV+NI V GV V+N PGANA + EL T +L+ +RH+ PA
Sbjct: 53 QVIGRAGVGVNNIPVRPLTLSGVPVLNTPGANANAVKELVITGILLASRHIYPALDYARH 112
Query: 418 -----STALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
T ++ ++G EL G+ ++G +VA GM IG+DP
Sbjct: 113 IEGDDETITHQVEKNKKRFSGFELPGKTLGIIGLGQIGVKVANAAIRLGMKAIGYDP 169
>UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: D-3-phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 328
Score = 62.1 bits (144), Expect = 1e-08
Identities = 34/109 (31%), Positives = 55/109 (50%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ KV+ R G G D +D+ +A + + V PG N S E L++ +AR A+
Sbjct: 70 DLKVISRYGVGFDAVDLAAADAQNIVVTITPGVNHHSVAEQAFALLMGIARMTRTQDRAV 129
Query: 430 KAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
++G W+R L + G R+G+ VATR GM+++ +DPF
Sbjct: 130 RSGEWEREL--TPRVWGSTIGIVGLGRIGQAVATRAIGMGMHVLAYDPF 176
>UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14;
Bacteroidetes|Rep: Predicted dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 337
Score = 62.1 bits (144), Expect = 1e-08
Identities = 34/116 (29%), Positives = 61/116 (52%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ + + + K +GR GAG++NIDV A KK + + AP N + E T ++L L
Sbjct: 79 DKEFIKKAKNLKFIGRVGAGLENIDVAYAKKKNIFLAAAPEGNRNAVGEHTLGMLLSLFN 138
Query: 403 HVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
++ A+ ++ G+WDR G EL G+ +G+ A ++ F + ++ +D
Sbjct: 139 NLNKANLEVRNGKWDREGNRGVELDGKTVGIIGYGNMGKAFAKKLRGFDVEVLCYD 194
>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative dehydrogenase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 318
Score = 61.7 bits (143), Expect = 2e-08
Identities = 37/124 (29%), Positives = 58/124 (46%), Gaps = 3/124 (2%)
Frame = +1
Query: 211 SNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLML 390
S S D+ + K++ GAG +N+D+D A ++ + V N P A+ S ELT L+L
Sbjct: 54 STSVDKEVIDAANNLKIITNYGAGFNNVDIDYARQQNIDVTNTPKASTNSTAELTFALVL 113
Query: 391 VLARHVVPASTALKA---GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
+AR + + W + G E++G+ +G VA R AF MNI+
Sbjct: 114 AVARRIPEGDKLCRTTGFDGWAPLFFRGREVSGKTIGIIGLGEIGSAVARRAKAFDMNIL 173
Query: 562 GFDP 573
P
Sbjct: 174 YTGP 177
>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
D-3-phosphoglycerate dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 528
Score = 61.7 bits (143), Expect = 2e-08
Identities = 31/110 (28%), Positives = 56/110 (50%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
+ K++ RAG GV+NI +D+A KG+ V N P + + E +M+ LAR + A +
Sbjct: 63 KRLKIIARAGIGVENIAMDAANIKGIVVTNTPLGSTTTIAEHAIAMMMSLARLIPQAHES 122
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ G+W + GS++ + ++GR V M++ +DP+
Sbjct: 123 MSQGKWQSTEFLGSDINDKTLGVIGGGKIGRRVIEYARGLHMHVNLYDPY 172
Score = 35.5 bits (78), Expect = 1.3
Identities = 22/59 (37%), Positives = 34/59 (57%), Gaps = 1/59 (1%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLN-AYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
VLI D + +L + A GI + I+ + LL I N+DAL+VR T V++E++ A
Sbjct: 3 VLISDNFSSAGLKLFDEAEGITADYQPGITHDNLLKIINNYDALIVRGGTTVSEELIFA 61
>UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Dinoroseobacter shibae
DFL 12|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Dinoroseobacter shibae DFL
12
Length = 316
Score = 61.7 bits (143), Expect = 2e-08
Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+G G G+DNID+ + +G+ V A GAN S E T L+L R ++ ++
Sbjct: 68 RVIGLLGTGLDNIDMAACAARGISVHPATGANTRSVAEYVITAALMLTRRAFMSTPEMQE 127
Query: 436 GRWDRA-LYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G W R L G E+AG+ V + VA M I+G DP
Sbjct: 128 GAWPRGPLGEGGEIAGRKLGLYGCGAVAQAVARLAKPLSMTILGHDP 174
>UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 355
Score = 61.3 bits (142), Expect = 2e-08
Identities = 33/113 (29%), Positives = 53/113 (46%)
Frame = +1
Query: 238 GRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 417
G+ K + G GVDN+D + + G+ + N PG ++ ++ LAR
Sbjct: 109 GKAGRLKAAVKWGVGVDNVDFAACQRLGLPISNTPGMFGREVADVAVGYVIALARQTFAI 168
Query: 418 STALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+KAG W ++ G LAG+ +GR A R++A M I+ +DPF
Sbjct: 169 DRTVKAGGWIKS--AGISLAGKTVALAGFGDIGRNTARRLFAAEMKIVAYDPF 219
>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermosinus carboxydivorans Nor1
Length = 365
Score = 61.3 bits (142), Expect = 2e-08
Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 3/110 (2%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
++VG + AG++N++V A K+G+ V N G NA + + T LML R++ A ++K
Sbjct: 97 RIVGVSRAGLENVNVKEATKRGILVFNIEGRNAEAVSDFTVGLMLAECRNIARAHYSIKN 156
Query: 436 GRWDRALYTGS---ELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G W + EL G+ +GR VA ++ FG+ + +DPF
Sbjct: 157 GGWRKEFSNSDWVPELKGKKVGLVGFGYIGRLVAQKLSGFGVTRLVYDPF 206
>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
related dehydrogenase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 312
Score = 60.9 bits (141), Expect = 3e-08
Identities = 29/61 (47%), Positives = 40/61 (65%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K++ R G G DNI V+SA K GV V N PGANA++ EL TL+L + R V A+ +++
Sbjct: 67 KLIARRGVGYDNIPVESATKHGVWVTNTPGANAIAVAELAVTLILTVLRKVNQATNSVQK 126
Query: 436 G 438
G
Sbjct: 127 G 127
>UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6;
Cyanobacteria|Rep: Predicted dehydrogenase - Nodularia
spumigena CCY 9414
Length = 341
Score = 60.9 bits (141), Expect = 3e-08
Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 2/120 (1%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D + +G ++ KV+ +G G D ID+ A K GV V+N PG + + E T ++L LA+
Sbjct: 69 DAQAIGLAKKLKVISTSGFGTDAIDISVATKHGVVVVNNPGLSTTAVAEHTICMILALAK 128
Query: 403 HVVPASTALKAGRW-DRALYTGSELAGQDPRHPWPWRVGREVATR-MYAFGMNIIGFDPF 576
+ + +K G + R +L G+ R+G VA++ AF M ++ +DP+
Sbjct: 129 KLTFLNQCVKTGNYLIRNQVQPMQLEGKTLGIVGLGRIGSAVASKCSAAFQMRVLAYDPY 188
>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
Bacillaceae|Rep: Glycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 314
Score = 60.5 bits (140), Expect = 4e-08
Identities = 35/108 (32%), Positives = 55/108 (50%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K + + GAG DNID A +KG+ V N PG NA + +L LML AR++ + L+
Sbjct: 71 KYIMKFGAGYDNIDFKYAREKGIPVTNTPGQNADAVADLAIGLMLATARNIPAKNEELRN 130
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFR 579
G W+ L G E+ + +G+ +A R F M ++ + F+
Sbjct: 131 GNWE--LSMGIEIFQKKLGIIGFGAIGQAIAQRATGFQMEVLAYGTFQ 176
>UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp.
SK209-2-6|Rep: Dehydrogenase - Roseobacter sp. SK209-2-6
Length = 343
Score = 60.5 bits (140), Expect = 4e-08
Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 1/115 (0%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ R + +V+ R G GVD +DV++A KG+ V N + L L LAR +
Sbjct: 73 ITRMQRCEVIARYGVGVDIVDVNAATAKGILVTNVQNYCTEEVADHAIALWLALARKLPD 132
Query: 415 ASTALKAGRWD-RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
A AG W ++ L G+ ++G+ +A R AFG+N+I +DPF
Sbjct: 133 YDRATHAGLWQWQSGQPVHRLRGRTMGVVSLGKIGQAIAARARAFGVNVIAYDPF 187
>UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Chlorobium limicola DSM 245|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Chlorobium limicola DSM 245
Length = 305
Score = 60.1 bits (139), Expect = 5e-08
Identities = 32/105 (30%), Positives = 55/105 (52%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+ + R G G+D++D+D A +KG+ V N P S ELT + L L R V A +K
Sbjct: 72 RCISRVGVGMDSVDLDYAKQKGIVVTNTPDGPTRSVAELTIAMTLALLRKVPQAHMNIKQ 131
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
G W + + G+ + + ++G+ A++ AFG +++ FD
Sbjct: 132 GVWKKEI--GNLMYEKKVGLIGLGKIGKLAASQFQAFGCSVMAFD 174
>UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Xanthobacter sp. (strain Py2)
Length = 359
Score = 60.1 bits (139), Expect = 5e-08
Identities = 36/104 (34%), Positives = 55/104 (52%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ KV+ R G G D +DVD+A G V A GAN + + T LML + R + + A+
Sbjct: 104 QLKVIARRGVGYDRVDVDAARDLGRVVTIAAGANDPAVADHTIALMLAVLRRLKASQAAI 163
Query: 430 KAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
G W R L G++L G+ R+GR+VA R+ F + ++
Sbjct: 164 ARGDW-RVL-VGADLTGKTVGLIGFGRIGRQVARRLSGFDVTVL 205
>UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2,
putative; n=2; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase 2, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 508
Score = 60.1 bits (139), Expect = 5e-08
Identities = 32/115 (27%), Positives = 61/115 (53%), Gaps = 2/115 (1%)
Frame = +1
Query: 280 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 459
G + +D++ A K+G+ V N+P +N+ S EL + ++ L+R ++ + ++AG W++
Sbjct: 172 GTNQVDLEHAAKRGIAVFNSPFSNSRSVAELVISEIIALSRQIIDRTHEMRAGIWNKLSK 231
Query: 460 TGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD--PFRVC*SVRPVPLHQD 618
E+ G+ +G +++ AFGM++I FD P S R V +D
Sbjct: 232 NCWEIRGKTLGIVGYGHIGSQLSVLAEAFGMSVIYFDVVPIMPLGSARQVDTLED 286
Score = 41.9 bits (94), Expect = 0.015
Identities = 20/60 (33%), Positives = 40/60 (66%), Gaps = 2/60 (3%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
+L+++ + A+ L + G + TKA ++EEL+ ++PN+ A+ +RS T++T +V+DA
Sbjct: 101 ILLLENINLDAADYLKSQGYEVDHVTKA-YTEEELIAKLPNYHAIGIRSKTKITAKVIDA 159
>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
Staphylococcus|Rep: Glycerate dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 323
Score = 59.7 bits (138), Expect = 7e-08
Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Frame = +1
Query: 211 SNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLML 390
S D+ R ++ KV+ G DNID+ A K GV V N P + EL TLML
Sbjct: 54 SEHIDEEVFLRAQQLKVIANMAVGFDNIDISLAKKHGVVVTNTPHVLTETTAELGFTLML 113
Query: 391 VLARHVVPASTALKAGRWDR---ALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
+AR ++ A++ ++ G+W L +G ++ G +G+ A R+ F II
Sbjct: 114 TVARRIIEATSYIQEGKWKSWGPYLLSGKDVYGATVGIFGMGDIGKAFARRLQGFDARII 173
>UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
D-3-phosphoglycerate dehydrogenase - Lactobacillus
salivarius subsp. salivarius (strain UCC118)
Length = 394
Score = 59.7 bits (138), Expect = 7e-08
Identities = 40/114 (35%), Positives = 57/114 (50%), Gaps = 9/114 (7%)
Frame = +1
Query: 262 VGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV-VPASTALKAG 438
+ RAGAGV+NI ++ A +G V N PG+NA + EL T++L+ R V A K
Sbjct: 53 IARAGAGVNNIPLEKATSQGTAVFNTPGSNANAVKELIITMLLLSVRPVFASVKWAQKLA 112
Query: 439 RWDRALYT--------GSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
D +L T G+EL G+ +G VA GM +IG+DP+
Sbjct: 113 GADVSLQTEKGKNHFAGTELYGKKIGIIGLGNIGSRVAKACMDLGMKVIGYDPY 166
>UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: D-3-phosphoglycerate dehydrogenase, putative -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 352
Score = 59.7 bits (138), Expect = 7e-08
Identities = 38/113 (33%), Positives = 54/113 (47%), Gaps = 4/113 (3%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ + VG G N+D+ +A + GV V APG NA +A E L+L R + + L
Sbjct: 87 DLRFVGVCRGGPVNVDLQAATEAGVVVSYAPGRNAAAAAEFAVGLVLAALRRIPASDAEL 146
Query: 430 KAGRWDRALY----TGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
K+G W Y G EL G +GR VA + AFG +++ DPF
Sbjct: 147 KSGNWRGDYYAYENAGIELEGSTVGLVGYGAIGRIVARVLAAFGAHVLVADPF 199
>UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor; n=2;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor - Rhodopseudomonas
palustris (strain BisB18)
Length = 336
Score = 59.3 bits (137), Expect = 9e-08
Identities = 38/112 (33%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
++ KV+ R G+G D +D+ +A K GV V+NAP AN+ S EL ML +R+
Sbjct: 83 KKLKVLVRHGSGYDTVDLAAAKKHGVTVLNAPLANSTSVAELALFYMLHCSRNFRLVQQT 142
Query: 427 LKAGRWDRALYT-GSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFR 579
+ + L T SE+A + +G VA F M +IGFDP++
Sbjct: 143 MLVDYYKAKLDTPKSEIACKKLGLIGVGNIGSRVAKMARGFDMQVIGFDPYK 194
>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Clostridium phytofermentans ISDg|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Clostridium phytofermentans ISDg
Length = 316
Score = 59.3 bits (137), Expect = 9e-08
Identities = 37/106 (34%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+GR G G DNID+ A +G+ V P ANA S E T L+L A+++V A L+
Sbjct: 66 KVIGRHGVGYDNIDIAEATAQGIKVCYTPLANANSVAEHTIMLLLACAKNIVIADKELRQ 125
Query: 436 GRWD-RALYTGSELAGQDPRHPWPWRVGREVATR-MYAFGMNIIGF 567
G ++ R G ++ G+ R+G+ VA + GM I+ +
Sbjct: 126 GNYEIRNQMPGIDVFGKTLGIIGFGRIGKSVAKKAALGLGMKILAY 171
>UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 342
Score = 59.3 bits (137), Expect = 9e-08
Identities = 38/131 (29%), Positives = 67/131 (51%), Gaps = 5/131 (3%)
Frame = +1
Query: 202 CAFSNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCT 381
C + + ++ + + ++V + G G+D ID++ A ++GV V G+NA + E T
Sbjct: 56 CLVTTAITEKLLQESPKLRLVHKWGIGIDKIDLEGAERQGVYVAITAGSNAGAVAEHTIM 115
Query: 382 LMLVLARHVVPASTALKAGRWDRALYTG-----SELAGQDPRHPWPWRVGREVATRMYAF 546
L+L R + A +++ G+W +YT +L+G+ +GR VA R+ F
Sbjct: 116 LILAALRRLALADQSMREGKW---IYTELRPLCRKLSGKTVGILGFGNIGRNVAQRLQGF 172
Query: 547 GMNIIGFDPFR 579
+ II DPFR
Sbjct: 173 DVEIIYHDPFR 183
>UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mycobacterium gilvum
PYR-GCK|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Mycobacterium gilvum
PYR-GCK
Length = 298
Score = 59.3 bits (137), Expect = 9e-08
Identities = 35/107 (32%), Positives = 51/107 (47%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K V R G G+D++D ++A + GV V N PG + +L LAR + A++
Sbjct: 64 KTVIRWGIGMDSVDHEAARRHGVTVRNTPGVFGYEVADSAFGYILNLARGYMAVDAAVRR 123
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G W + G L G +GRE+A R FG ++ FDPF
Sbjct: 124 GEWPKV--EGITLDGSRLGIVGFGAIGREIAKRGAGFGQEVVAFDPF 168
>UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6;
Alphaproteobacteria|Rep: Putative uncharacterized
protein - Roseobacter sp. SK209-2-6
Length = 166
Score = 59.3 bits (137), Expect = 9e-08
Identities = 34/72 (47%), Positives = 38/72 (52%)
Frame = -2
Query: 473 SSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALITPTPFLPAESTS 294
SS+P+ SHLPA+ EA WRA NI S + L G IT TP L A S S
Sbjct: 13 SSVPMNLDFSHLPAWVEAEASGIWRATANIIAMACSAVVIILPNGVFITITPRLEAASLS 72
Query: 293 MLSTPAPARPTT 258
MLS P PAR T
Sbjct: 73 MLSVPMPARAMT 84
>UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12;
Bacteria|Rep: Glycerate dehydrogenase - Geobacter
sulfurreducens
Length = 327
Score = 58.8 bits (136), Expect = 1e-07
Identities = 43/135 (31%), Positives = 66/135 (48%), Gaps = 6/135 (4%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ + + + + G +N+DV++AGK+G+ V N P + S + T L+L LA
Sbjct: 60 DEATLAALPKLRYISMLATGYNNVDVEAAGKRGIPVANIPAYSTESVVQTTFALLLELAV 119
Query: 403 HVVPASTALKAGRW----DRALYTGS--ELAGQDPRHPWPWRVGREVATRMYAFGMNIIG 564
HV +A+KA W D + + EL G +GR VA AFGM I+
Sbjct: 120 HVGIHDSAVKAREWVRSPDHSFWKTPIVELDGLTLGIVGYGTIGRAVARVGAAFGMKIMA 179
Query: 565 FDPFRVC*SVRPVPL 609
+ P RV + PVP+
Sbjct: 180 YAP-RVPADLGPVPV 193
>UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-terminal
domain; n=1; Symbiobacterium thermophilum|Rep:
Phosphoglycerate dehydrogenase, N-terminal domain -
Symbiobacterium thermophilum
Length = 140
Score = 58.8 bits (136), Expect = 1e-07
Identities = 27/65 (41%), Positives = 41/65 (63%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ +V+ + G GVDNIDV +A ++G+ V+N P ANA+S E + LA+ VV A+
Sbjct: 65 DLRVIAKHGVGVDNIDVAAATERGILVLNTPEANAVSVAEHAIAAIAALAKRVVFMDRAV 124
Query: 430 KAGRW 444
+ GRW
Sbjct: 125 RDGRW 129
>UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep:
Dehydrogenase - Geobacillus kaustophilus
Length = 334
Score = 58.8 bits (136), Expect = 1e-07
Identities = 33/118 (27%), Positives = 62/118 (52%), Gaps = 4/118 (3%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ + + K++ R G GV+ +DVD+A +KG+ V N + + L+L LAR +V
Sbjct: 63 IAQLEKCKIISRYGVGVNTVDVDAATEKGIIVANVTDYSIDEVSDHALALLLSLARKIVK 122
Query: 415 ASTALKAGRWD----RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ +K+G W+ + +Y L G+ R+ + +A + AFG+ +I +DP+
Sbjct: 123 LNHEVKSGTWNFNVGKPIY---RLRGRTLGLVGLGRIPQALAKKAQAFGLRVIAYDPY 177
>UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388;
n=1; Pyrococcus horikoshii|Rep: Putative uncharacterized
protein PH1388 - Pyrococcus horikoshii
Length = 119
Score = 58.8 bits (136), Expect = 1e-07
Identities = 39/91 (42%), Positives = 48/91 (52%), Gaps = 1/91 (1%)
Frame = -2
Query: 479 PASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALITPTPFLPAES 300
P+SS+P+ +H P+ + A + A NIN SS L LA GAL T PF A S
Sbjct: 7 PSSSIPIASFFAHTPSLIFLSAKAIFLATENINPTASSATLLELAAGALTTSIPFSLAAS 66
Query: 299 TSMLSTPAPARPTTFA-SRLRPTPLWSLELL 210
TSMLS P PA T + L T L +L LL
Sbjct: 67 TSMLSKPTPALAITLSFGALSITLLVTLGLL 97
>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
Bacilli|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 324
Score = 58.4 bits (135), Expect = 2e-07
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 3/120 (2%)
Frame = +1
Query: 211 SNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLML 390
S DQ + K++ GAG +NID+ +A K+ + V N P +A++ E T L++
Sbjct: 54 STQVDQDVLDHAPHLKLIANFGAGTNNIDIAAAAKRQIPVTNTPNVSAVATAESTVGLII 113
Query: 391 VLARHVVPASTALKA---GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
LA +V ++ W + G L G+ ++G+ VA R++AF M I+
Sbjct: 114 SLAHRIVEGDHLMRTSGFNGWAPLFFLGHNLQGKTLGILGLGQIGQAVAKRLHAFDMPIL 173
>UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein; n=2; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein - Salinibacter
ruber (strain DSM 13855)
Length = 321
Score = 58.4 bits (135), Expect = 2e-07
Identities = 44/138 (31%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
++V + GVDNID+++A V V + PG + + L+L ARHV A ++
Sbjct: 70 QMVSQYAVGVDNIDLEAAEAHDVAVTHTPGVLTDATADQAWALLLAAARHVPAADRYVRD 129
Query: 436 G---RWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFRVC*SV-RPV 603
G RW+ G ELA + R+G VA R FGM +I + R +V R V
Sbjct: 130 GRFERWETTHLMGMELARKTIGIVGMGRIGTAVARRALGFGMEVIYHNRTRANPTVERQV 189
Query: 604 PLHQDGAGGHLASSGSTS 657
G G L +S S
Sbjct: 190 SARHVGLGELLTTSDVVS 207
>UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Enterococcus faecium DO|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Enterococcus faecium DO
Length = 386
Score = 58.4 bits (135), Expect = 2e-07
Identities = 35/111 (31%), Positives = 57/111 (51%), Gaps = 9/111 (8%)
Frame = +1
Query: 262 VGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS------- 420
+ RAG GV+ I+V+ A + G V+N PG NA + EL +L+ +R ++ AS
Sbjct: 53 ISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPIIEASRMVQTLT 112
Query: 421 --TALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGF 567
L+ R+ Y G EL G+ +G +VA Y+ GM+++G+
Sbjct: 113 GPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDVLGY 163
>UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Aspergillus fumigatus|Rep: D-3-phosphoglycerate
dehydrogenase - Aspergillus fumigatus (Sartorya
fumigata)
Length = 635
Score = 58.4 bits (135), Expect = 2e-07
Identities = 24/63 (38%), Positives = 43/63 (68%)
Frame = +1
Query: 295 DVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSEL 474
DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++LK+G+W+R+ + G E+
Sbjct: 109 DVEEATKLGIVVVNSPSGNIGAAAEHTIALLMAMARNIPEACSSLKSGKWERSKFVGVEV 168
Query: 475 AGQ 483
G+
Sbjct: 169 KGK 171
Score = 34.3 bits (75), Expect = 2.9
Identities = 21/58 (36%), Positives = 32/58 (55%)
Frame = +2
Query: 71 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 244
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTANLLRA 67
>UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|Rep:
Glycerate dehydrogenase - Uncultured methanogenic
archaeon RC-I
Length = 319
Score = 58.4 bits (135), Expect = 2e-07
Identities = 32/105 (30%), Positives = 53/105 (50%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K+V G D++D+D+A KGV V NAPG + + E ++L R + A ++
Sbjct: 67 KLVALTRTGYDDVDLDAATLKGVAVANAPGYSNEAVAEHVFAMLLSFIRRISEADFWIRE 126
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
++D + G EL G+ ++G VA FGM++I +D
Sbjct: 127 EKFDCTAFEGRELRGKTMGIIGTGQIGLRVAEIARCFGMDVIAYD 171
>UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative glycerate
dehydrogenase - Streptomyces avermitilis
Length = 325
Score = 58.0 bits (134), Expect = 2e-07
Identities = 39/108 (36%), Positives = 57/108 (52%), Gaps = 4/108 (3%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVIN--APGANALSACELTCTLMLVLARHVVPAST 423
E +++ A G D +D+D+A +G+ V N + GA + E T LML LA+ +VPA T
Sbjct: 70 ELQLIQCASHGFDYVDLDAARARGLPVCNIGSSGAEQQNVAEQTFALMLALAKQLVPAHT 129
Query: 424 ALKAGRW--DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
AL W R + +EL+G+ +G EVA R AF M I+
Sbjct: 130 ALVDADWALPRLQRSITELSGKTLGIVGLGHIGEEVARRAVAFDMRIV 177
>UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding precursor; n=1;
Chlorobium phaeobacteroides BS1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding
precursor - Chlorobium phaeobacteroides BS1
Length = 312
Score = 58.0 bits (134), Expect = 2e-07
Identities = 31/110 (28%), Positives = 53/110 (48%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ + + R GAG++NID+ SA K V +NAP N + E ++L L ++ A +
Sbjct: 66 QLRFIARVGAGMENIDIQSADKHQVVCLNAPEGNRDAVAEQAVGMILTLFNRLLIADAEV 125
Query: 430 KAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFR 579
+ G W R G EL G+ G A ++ F + I+ +D ++
Sbjct: 126 RKGIWLREQNRGIELGGKTVGIIGYGNTGSAFARKLQGFDVRILAYDKYK 175
>UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Rhodobacteraceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Rhodobacter sphaeroides (strain ATCC 17029
/ ATH 2.4.9)
Length = 331
Score = 58.0 bits (134), Expect = 2e-07
Identities = 44/114 (38%), Positives = 56/114 (49%), Gaps = 2/114 (1%)
Frame = +1
Query: 238 GRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 417
G R A VV GAG D +D ++A +KGV V N PGANA S EL L L +AR + A
Sbjct: 60 GDRLRAVVVH--GAGHDPVDKEAAARKGVVVANTPGANARSVAELAVGLALAVARRIPAA 117
Query: 418 STALKAGRWD-RALYTGSELAGQDPRHPWPWRVGREVATRM-YAFGMNIIGFDP 573
AL+ G+ R SEL G+ GRE + AF M ++ P
Sbjct: 118 DRALREGKTGFRESARFSELRGRTALVVGWGASGRETGRMLAQAFDMRLLVHSP 171
>UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 317
Score = 58.0 bits (134), Expect = 2e-07
Identities = 38/107 (35%), Positives = 56/107 (52%), Gaps = 2/107 (1%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+GR G G+D ID+ A ++GV V+ P AN S E + ++LA+ + AL+
Sbjct: 68 KVIGRHGVGLDAIDLRCAKERGVKVVFTPTANTESVAEHFVGMAIMLAKMIRTGDIALRT 127
Query: 436 GRW-DRALYTGSELAGQDPRHPWPWRVGREVA-TRMYAFGMNIIGFD 570
G W R G+EL G+ R+GR+ A F MN+I +D
Sbjct: 128 GDWAARNRLIGTELHGKALGVLGFGRIGRQTARICRNGFAMNVIYYD 174
>UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr3 scaffold_8, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 418
Score = 58.0 bits (134), Expect = 2e-07
Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 4/116 (3%)
Frame = +1
Query: 244 RREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 423
R + G +N+DV++A K GV V N PG + EL +L + AR +V A
Sbjct: 84 RAGGRAFSNMAVGYNNVDVNAANKYGVAVGNTPGVLTETTAELAASLSMAAARRIVEADE 143
Query: 424 ALKAGRWD---RALYTGSELAGQDPRHPWPWRVGREVATRMY-AFGMNIIGFDPFR 579
++AG +D L+ G+ L GQ R+G A M F MN+I +D ++
Sbjct: 144 FMRAGLYDGWLPHLFVGNLLRGQTVGVIGAGRIGSAYARMMVEGFKMNLIYYDLYQ 199
>UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related
dehydrogenases; n=8; cellular organisms|Rep: Lactate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 358
Score = 57.6 bits (133), Expect = 3e-07
Identities = 38/111 (34%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPG-ANALSACELTCTLMLVLARHVVPASTA 426
E ++ R G G D ID++SA KKG V G + E L+L + R V AS
Sbjct: 94 ETLLIARHGIGYDAIDIESATKKGTIVTIVEGIVEREAVAENAVALLLDVMRKVREASIK 153
Query: 427 LKAGRW-DRALYTGSELAGQDPRHPWPWRVGREVATRM-YAFGMNIIGFDP 573
+K G+W +RA + G E+ G+ +G VA + Y FG +I +DP
Sbjct: 154 VKEGKWHERANFIGYEIKGKTAGIIGIGNIGSRVAEILKYGFGAEVIAYDP 204
>UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3;
Escherichia coli|Rep: Phosphoglycerate dehydrogenase -
Escherichia coli
Length = 306
Score = 57.6 bits (133), Expect = 3e-07
Identities = 36/113 (31%), Positives = 58/113 (51%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ + + KV+ + G G+DNIDVD A K + V A AN++S E+T +ML +R V
Sbjct: 65 IDQAKNLKVISKYGVGLDNIDVDYANSKDIVVHKALNANSISVAEMTILMMLSSSRKYVE 124
Query: 415 ASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
+ + G+ R + G EL ++ +G+ VA ++ GM I DP
Sbjct: 125 IESQARNGKDIRLV--GYELYQKNLGLIGLGAIGQHVAHIAHSMGMTITAHDP 175
>UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative;
n=4; Archaea|Rep: 2-hydroxyacid dehydrogenase, putative
- Archaeoglobus fulgidus
Length = 323
Score = 57.6 bits (133), Expect = 3e-07
Identities = 37/110 (33%), Positives = 56/110 (50%), Gaps = 3/110 (2%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ K++ + G +NIDV++A K + V N G NALS E T L L R ++ A ++
Sbjct: 70 KVKLIQQPSTGYNNIDVEAAKKLSITVANVGGVNALSVAEHTVMFALALLRRLIYAHNSV 129
Query: 430 KAGRWDR---ALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
+GRW++ A EL G+ GREV R+ +G+ II D
Sbjct: 130 LSGRWEQDEMANLGVYELHGKTWGIIGMGAQGREVTKRLQGWGVKIIYHD 179
>UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Comamonas testosteroni
KF-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 320
Score = 57.2 bits (132), Expect = 4e-07
Identities = 32/106 (30%), Positives = 51/106 (48%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
++V + GAGVD++D+++A +GV V A ANA + E LML L R + ++A
Sbjct: 76 RIVAKNGAGVDSVDMEAARTQGVAVAVAQAANAPAVAEHALALMLALVRQLPQLDQQVRA 135
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G W + + G + G +GR A A G ++ P
Sbjct: 136 GGWAGSNWQGRDFRGSTVGIVGYGAIGRATAQLAAALGAKVLVLRP 181
>UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 322
Score = 56.8 bits (131), Expect = 5e-07
Identities = 32/107 (29%), Positives = 49/107 (45%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+++ G D +D +A ++G+ V N PG NA + + T ML L RH ++
Sbjct: 75 RLIQSVAVGFDGVDHVAAAERGIPVANLPGFNADAVADWTVGAMLHLLRHYAAGHRKVEQ 134
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G W G +L+ +GR VA R+ FG I+ DPF
Sbjct: 135 GGWGPEGLRGRDLSALTVAILGFGNIGRAVARRLDGFGAEIVVHDPF 181
>UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Haloarcula marismortui|Rep: D-3-phosphoglycerate
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 323
Score = 56.8 bits (131), Expect = 5e-07
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KVVGRAG G+DNI V +A GV V+N P + T LML R + ++K
Sbjct: 70 KVVGRAGIGMDNIAVRAAVAAGVTVVNVPDYSVEEVSTHTFALMLACLRRIPTFDRSVKR 129
Query: 436 GRWDRAL-YTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G W A+ LAG ++ A ++ F +++I +DP+
Sbjct: 130 GEWKWAVGQPIRRLAGSTVGLVAFGKLASRFAAKLRGFDIDVIAYDPY 177
>UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH); n=2; Rattus
norvegicus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH) - Rattus
norvegicus
Length = 155
Score = 56.0 bits (129), Expect = 8e-07
Identities = 34/99 (34%), Positives = 54/99 (54%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
V ++ +VVG AG G+DN+D+++A +K + V+N N+LS ELTC + L A P
Sbjct: 59 VNAAQKLQVVGSAGTGMDNVDLEAAMRKSILVMNTSNGNSLSPVELTCGMNLCQAD--FP 116
Query: 415 ASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVAT 531
+ + + G+ L G+ + R+GREVAT
Sbjct: 117 GNNFNERWQMGPEEVHGATLTGKTLGNLGLGRIGREVAT 155
Score = 37.1 bits (82), Expect = 0.41
Identities = 21/65 (32%), Positives = 38/65 (58%)
Frame = +2
Query: 59 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 238
+I VLI D + C ++L G+ ++KEEL+ E+ + + L ++SAT+VT + +
Sbjct: 5 NICKVLISDSLDPCCQKILQDGGLQN-----LNKEELITELQDCEGLTIQSATKVTADAV 59
Query: 239 DAGVK 253
+A K
Sbjct: 60 NAAQK 64
>UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase, partial - Macaca mulatta
Length = 333
Score = 56.0 bits (129), Expect = 8e-07
Identities = 28/71 (39%), Positives = 42/71 (59%)
Frame = +1
Query: 211 SNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLML 390
S+ D+ R + K+V RAGAGVD ID+D+A K V V N PG NA + E+ L++
Sbjct: 113 SDKLDEEFFNRAKNLKIVVRAGAGVDTIDLDAASKHHVVVENTPGQNANAVAEMVFALLI 172
Query: 391 VLARHVVPAST 423
+ R+ A++
Sbjct: 173 AMKRNHFDATS 183
>UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Bacteroides fragilis
Length = 306
Score = 56.0 bits (129), Expect = 8e-07
Identities = 39/122 (31%), Positives = 59/122 (48%)
Frame = +1
Query: 211 SNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLML 390
S+ D + +E K+V RAGAG DN+D+++A GV V+N PG N+ + EL L++
Sbjct: 56 SDIIDAEVLDAAKELKIVVRAGAGYDNVDLNAATAHGVCVMNTPGQNSNAVAELVFGLLV 115
Query: 391 VLARHVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
R+ + +G+EL G+ VGR VA FGM + +D
Sbjct: 116 YAVRNFYNGT-------------SGTELMGKKLGIHAYGNVGRNVARIAKGFGMELYAYD 162
Query: 571 PF 576
F
Sbjct: 163 AF 164
>UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=1; Endoriftia persephone
'Hot96_1+Hot96_2'|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase - Endoriftia persephone 'Hot96_1+Hot96_2'
Length = 204
Score = 56.0 bits (129), Expect = 8e-07
Identities = 26/54 (48%), Positives = 36/54 (66%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 408
+ + +GRAGAGV+NI VD +G+ V NAPGANA + EL ML+ AR++
Sbjct: 49 KTVQAIGRAGAGVNNIPVDKMTARGISVFNAPGANANAVKELVVAGMLLAARNI 102
>UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 380
Score = 56.0 bits (129), Expect = 8e-07
Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
R K++ AG DN+D + A ++G+ V+ P + LS E +M+ L RH+ +
Sbjct: 101 RGVKLILLRCAGFDNVDCERARERGISVLRVPAYDPLSISEHAVAMMMSLNRHLCASRDR 160
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRM-YAFGMNIIGFDPF 576
L+ G + GS + G+ ++GR VA + F M ++G+D F
Sbjct: 161 LRMGNFTLDGLVGSSMRGKTVGVVGTGKIGRGVAEILKNGFQMRVLGYDKF 211
>UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative; n=5;
Eurotiomycetidae|Rep: NAD-dependant D-isomer specific
2-hydroxyacid dehydrogenase, putative - Aspergillus
fumigatus (Sartorya fumigata)
Length = 335
Score = 56.0 bits (129), Expect = 8e-07
Identities = 33/104 (31%), Positives = 51/104 (49%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
+ K + GAG DNID+ + +KG+ V + P A + ++ LM+ R +A
Sbjct: 75 KSLKYICHNGAGYDNIDIPACSEKGIAVSSTPVAVNHATADVGIFLMIGALRQAYIPLSA 134
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNI 558
L+AG+W G + G+ +GRE+A R AFGM I
Sbjct: 135 LRAGQWQGKTTLGHDPQGKVLGILGMGGIGREMANRARAFGMKI 178
>UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate
dehydrogenase; n=1; Desulfotalea psychrophila|Rep:
Related to D-3-phosphoglycerate dehydrogenase -
Desulfotalea psychrophila
Length = 393
Score = 55.6 bits (128), Expect = 1e-06
Identities = 38/116 (32%), Positives = 61/116 (52%), Gaps = 12/116 (10%)
Frame = +1
Query: 262 VGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV------VPAST 423
V RAGAG +N++V+ A KKG+ V N PGANA + +L ++ V R++ + T
Sbjct: 54 VARAGAGTNNVNVERATKKGICVFNTPGANANAVVDLVFPMLGVWKRNIFNGINFCKSLT 113
Query: 424 ALKAGRWD------RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
A+ + D ++ Y G E+AG++ ++G +A MN+ GFDP
Sbjct: 114 AVDPDKVDSVVEAQKSAYKGEEIAGKNLTVVGLGQIGVRLANGGIQRLMNVKGFDP 169
>UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: Probable 2-hydroxyacid
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 327
Score = 55.6 bits (128), Expect = 1e-06
Identities = 35/107 (32%), Positives = 51/107 (47%), Gaps = 3/107 (2%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
E +VV G DN+DV + + + V N PG + +L L+L AR++ AS
Sbjct: 73 ELRVVSNMAVGFDNVDVPACTARSIRVGNTPGVLTDATADLAMALLLSAARNLPAASLDA 132
Query: 430 KAGRWDR---ALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
+ GRW + G EL G ++G VA R AFGM+I+
Sbjct: 133 REGRWQTWSPTGWLGLELRGATLGVVGLGKIGLAVAQRARAFGMDIL 179
>UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 387
Score = 55.6 bits (128), Expect = 1e-06
Identities = 37/115 (32%), Positives = 55/115 (47%), Gaps = 10/115 (8%)
Frame = +1
Query: 262 VGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR 441
+ RAGAGV+NI +D KGV V N PGANA EL ML+ +R ++ + +
Sbjct: 53 IARAGAGVNNIPLDKCADKGVVVFNTPGANANGVKELVLCGMLLASRDIIGGNKWVANNT 112
Query: 442 WDRAL----------YTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
+ + + G+E+ G+ +GR VA + GM + G DPF
Sbjct: 113 DNENISKDMEKAKKNFAGNEIKGKKLGVIGLGAIGRLVANAAESMGMEVYGNDPF 167
>UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacteroidetes|Rep: D-3-phosphoglycerate dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 329
Score = 55.6 bits (128), Expect = 1e-06
Identities = 39/113 (34%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLM------LVLARHVVPA 417
K++GR G G+DNIDV A +KG+ VIN P A++ S EL + L A +P
Sbjct: 79 KLIGRGGVGMDNIDVAYAKEKGLHVINTPAASSESVAELVFAHLFGGVRFLYDANRNMPL 138
Query: 418 STALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
K + ++ GSEL G+ R+G+ A GM +I DPF
Sbjct: 139 EGDSKFKQLKKSYAGGSELRGKTLGVIGFGRIGQATAKIALGIGMKVIYSDPF 191
Score = 34.3 bits (75), Expect = 2.9
Identities = 26/65 (40%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Frame = +2
Query: 56 VDIKSVLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDA-LVVRSATQVT 226
V+ +L DG+ L A G I+TTT A+ +E + E N A L+VRSATQV
Sbjct: 11 VNSMKILANDGISQTGINELEAAGFEISTTTVAQEQLKEFINE--NQIAGLLVRSATQVR 68
Query: 227 KEVLD 241
K+++D
Sbjct: 69 KDIID 73
>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
organisms|Rep: Glyoxylate reductase - Pyrococcus
horikoshii
Length = 334
Score = 55.6 bits (128), Expect = 1e-06
Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 7/115 (6%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
++V G DNID++ A K+G+ V N P + +L L+L ARHVV +++
Sbjct: 69 RIVANYAVGYDNIDIEEATKRGIYVTNTPDVLTDATADLAFALLLATARHVVKGDRFVRS 128
Query: 436 GRWDR-------ALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFR 579
G W + + G ++ G+ R+G+ +A R F M I+ + R
Sbjct: 129 GEWKKRGVAWHPKWFLGYDVYGKTIGIIGLGRIGQAIAKRAKGFNMRILYYSRTR 183
>UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14;
cellular organisms|Rep: Phosphoglycerate dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 330
Score = 55.2 bits (127), Expect = 1e-06
Identities = 35/111 (31%), Positives = 53/111 (47%), Gaps = 4/111 (3%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K+V + G NID+ +A G+ V+N PG NA + E T +L R + AL+
Sbjct: 79 KLVAVSRGGPINIDMAAARAHGITVVNVPGRNATAVAEFTLGAILAETRLIRVGHEALRK 138
Query: 436 GRWDRALY----TGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G W LY TG EL+ +G +V + AFG +++ DP+
Sbjct: 139 GEWRGDLYRADRTGRELSEMTVGVIGYGNIGTKVVRLLRAFGCHVLVSDPY 189
>UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4558 protein - Bradyrhizobium
japonicum
Length = 329
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/112 (30%), Positives = 55/112 (49%), Gaps = 1/112 (0%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
++ KVV R G G D +DV + ++ V ++ A AN+ S E +ML LA+ +
Sbjct: 71 KDMKVVTRIGVGYDAVDVPALSRRKVPLMVAGSANSPSVAEQALFMMLTLAKRAQEMHSC 130
Query: 427 LKAGRW-DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFR 579
+K G+W DR +L G+ R+G A R A M + +DP++
Sbjct: 131 VKDGKWADRLGMLPFDLYGKTVLIIGFGRIGTRTAKRCLAMEMRVQVYDPYK 182
>UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Polaromonas sp.
JS666|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Polaromonas sp. (strain
JS666 / ATCC BAA-500)
Length = 309
Score = 55.2 bits (127), Expect = 1e-06
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+ G G D I V A +G+ V + PG + CEL L+L L R + + ++
Sbjct: 63 QVISTCGVGYDGIPVAYAQARGIAVTHTPGVLDDAVCELGVGLLLGLLRDIPASDRFVRD 122
Query: 436 GRW-DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGM 552
GRW D A + LAG+ R+GR +A R+ FG+
Sbjct: 123 GRWSDSAYPLTTSLAGKAVGIVGLGRIGRGIAARLQPFGV 162
>UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 316
Score = 55.2 bits (127), Expect = 1e-06
Identities = 35/103 (33%), Positives = 50/103 (48%), Gaps = 1/103 (0%)
Frame = +1
Query: 259 VVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG 438
V+ R G G DNI++ A +KG+ N PGA S E ++L+ AR + A+ + G
Sbjct: 68 VIARFGIGCDNINLPRAAEKGIYCTNTPGALEQSVAECAIGMILLAARQFIAAADDCRNG 127
Query: 439 RWDRALYTGSELAGQDPRHPWPWRVGREVAT-RMYAFGMNIIG 564
W TG ELAG+ +G VA FGM++ G
Sbjct: 128 LWQP--QTGCELAGKTLAVIGCGAIGSRVAAIAKNGFGMSVTG 168
>UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1;
Sagittula stellata E-37|Rep: 2-hydroxyacid dehydrogenase
- Sagittula stellata E-37
Length = 314
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 2/106 (1%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ +++ G G D +DV++A + GV V N P E+T LML LA V + +
Sbjct: 67 DLEIISSFGVGYDAVDVEAAKEHGVRVTNTPDVLNDCVAEVTLALMLALAHRVPESHAYV 126
Query: 430 KAGRWDR--ALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
+ GRW+ A+ +EL G R+G+ +A AF M ++
Sbjct: 127 RDGRWETEGAMPLTAELTGATVGIIGLGRIGKAIARLAQAFSMRVV 172
>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
Length = 332
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/107 (30%), Positives = 49/107 (45%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ K++ G D+IDV A KG+ V N P S E LML LAR + +
Sbjct: 65 DLKLIATRSTGFDHIDVAYANSKGITVCNVPSYGEESVSEYAIMLMLALARKLRETIDNV 124
Query: 430 KAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
+ G + + G ELAG+ R+G A FGM+++ +D
Sbjct: 125 EKGVYKTSNLRGIELAGKTLGVIGTGRIGARTALLARCFGMDVVCYD 171
>UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr7063 protein - Bradyrhizobium
japonicum
Length = 387
Score = 54.8 bits (126), Expect = 2e-06
Identities = 35/110 (31%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KV+ GVD++DV +A +G+ V N P + L+L R +V +++
Sbjct: 114 KVITLGSVGVDSVDVKAATARGIPVTNIPDTFIEEVADHAMMLLLAGFRRLVEQDRMVRS 173
Query: 436 GRWDR---ALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
GRW AL L GQ RV R VA R FG+ ++ +DPF
Sbjct: 174 GRWAEGRPALLKIPRLMGQTLGFISFGRVARAVAKRAAPFGLRMMAYDPF 223
>UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2;
Sclerotiniaceae|Rep: Formate dehydrogenase - Sclerotinia
sclerotiorum 1980
Length = 436
Score = 54.8 bits (126), Expect = 2e-06
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 4/108 (3%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKK--GVGVINAPGANALSACELTCTLMLVLARHV 408
+ + + K+ AG G D++D+++A K G+ V G+N +S E +LVL R+
Sbjct: 142 LAKAKNLKIAITAGIGSDHVDLNAANKTNGGITVAEVTGSNVVSVAEHVVMTILVLVRNF 201
Query: 409 VPASTALKAGRWDRALYTGSE--LAGQDPRHPWPWRVGREVATRMYAF 546
VPA ++AG WD A +E L G+ R+G V R+ F
Sbjct: 202 VPAHEQIQAGEWDVAAAAKNEFDLEGKVVGTVAVGRIGERVLRRLKPF 249
>UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2;
Thermoprotei|Rep: 2 lactate dehydrogenase - Cenarchaeum
symbiosum
Length = 348
Score = 54.8 bits (126), Expect = 2e-06
Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 4/108 (3%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ + + G D+IDV A +G+ V P + +LT LML L R V +
Sbjct: 101 DLETIATYSVGYDHIDVAHARGRGITVGYTPDVLTDATADLTMALMLDLLRRVTEGDRII 160
Query: 430 KAGRWDRAL----YTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
+AGRW + Y G+++ G+ R+G VA R AFGM +I
Sbjct: 161 RAGRWRQIYGADDYLGTDVGGKTLGILGMGRIGSRVAKRAAAFGMKVI 208
>UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family; n=2; Cyanobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase family -
Synechocystis sp. (strain PCC 6803)
Length = 318
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/113 (24%), Positives = 57/113 (50%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+G++ + K + + G GVD ID+ +A + G+ N P ++ +++LAR +
Sbjct: 68 IGKQGKLKALAKWGIGVDAIDLAAAKQLGILTSNTPNVFGDEVADVAIGYLILLARELHC 127
Query: 415 ASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
A++ G W + G L G+ +G+ +A R+ + G+ ++G+DP
Sbjct: 128 IDQAVRQGEWLK--IRGHSLRGKTAGIIGVGSIGQAIAVRLQSMGLKLLGYDP 178
>UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=1; Lawsonia intracellularis
PHE/MN1-00|Rep: Phosphoglycerate dehydrogenase and
related dehydrogenases - Lawsonia intracellularis
(strain PHE/MN1-00)
Length = 302
Score = 54.4 bits (125), Expect = 3e-06
Identities = 33/106 (31%), Positives = 55/106 (51%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K + G +DNIDV+ A +K + + N P A++ E T L+L L R + +++
Sbjct: 71 KTIACCGKHLDNIDVEYAQEKNIIIYNPPKGYAIAVAEFTVGLILSLIRQIPYQDKEVRS 130
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G W + + G+ L G+ +VG+ VA R+ FG++I DP
Sbjct: 131 GVWHKRI--GNLLHGKRVGIIGLGQVGKAVAERLLPFGVDIAYNDP 174
>UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Sphingomonas wittichii
RW1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Sphingomonas wittichii RW1
Length = 317
Score = 54.4 bits (125), Expect = 3e-06
Identities = 31/97 (31%), Positives = 50/97 (51%), Gaps = 3/97 (3%)
Frame = +1
Query: 280 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD---R 450
G+D+ID+D+ +G+ + N PG + + + L+L R + A+ L+ GRW
Sbjct: 78 GLDHIDLDAVRARGLPMFNTPGILSNAVADQAMLLLLAATRRMAEATALLREGRWTDLWS 137
Query: 451 ALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
+ G ELAG+ +GR VA R AFGM ++
Sbjct: 138 SHILGVELAGRTLGIYGLGDIGRRVARRATAFGMRLV 174
>UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 337
Score = 54.4 bits (125), Expect = 3e-06
Identities = 30/107 (28%), Positives = 49/107 (45%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+++ G D+ID+D G+ V N P + E L+L ++RH+V + +
Sbjct: 66 RLIATRSTGYDHIDLDYCRAHGIAVSNVPDYGDATVAEHAFALLLAVSRHIVTGAERTRR 125
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
G + + G EL G+ R+GR V FGM I+ +D F
Sbjct: 126 GDFSQHGLRGFELRGKTLGVLGTGRIGRRVIEIGKGFGMKIVAYDLF 172
>UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 322
Score = 54.4 bits (125), Expect = 3e-06
Identities = 36/108 (33%), Positives = 57/108 (52%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ K++ G +ID+ +A + G+ V+ G + +A ELT L+L LAR + L
Sbjct: 71 DLKLLVTTGMANQSIDLRAAEELGI-VVCGTGGSPTAAPELTWGLLLALARSISFEDRNL 129
Query: 430 KAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
+ GRW + G ELAG+ ++GR VA AFGM++I + P
Sbjct: 130 REGRWQSTV--GFELAGKTLGVLGLGKIGRRVAAYGQAFGMDVIAWSP 175
>UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1;
Acanthamoeba castellanii|Rep: Beta xylosidase-like
protein - Acanthamoeba castellanii (Amoeba)
Length = 222
Score = 54.4 bits (125), Expect = 3e-06
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 5/125 (4%)
Frame = +1
Query: 202 CAFSNSSDQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCT 381
C + +D V + + KV+ GAG D +DV +A ++ + V N PGA + ++
Sbjct: 28 CHGKDKADAELVAKGSKLKVISNFGAGYDTVDVKAATERNIWVCNTPGAVTNATADVALY 87
Query: 382 LMLVLARHVVPASTALKAGRWDR-----ALYTGSELAGQDPRHPWPWRVGREVATRMYAF 546
L+L R A L+ G W+R + G+ G+ +G+ +A R A
Sbjct: 88 LLLAACRRATEAERFLRDGSWERQGSDILAFWGNNPEGKTLGIIGMGNIGKALAKRAAAL 147
Query: 547 GMNII 561
M +I
Sbjct: 148 DMRVI 152
>UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 339
Score = 54.4 bits (125), Expect = 3e-06
Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+++ R G GVDN+ + + +G+ V N PG+NA + EL LML + R VV ++
Sbjct: 80 RIISRNGTGVDNVPLPTCLSRGIAVTNIPGSNAFAVAELAIALMLTVLRRVVEVDKRIRG 139
Query: 436 G-RWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G R L G+ + E+A + AFG ++ P
Sbjct: 140 GERVPSIEALAPGLGGKKVGLVGMGDIAYELAKLLRAFGCEVLIHSP 186
>UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=51;
Bacteria|Rep: 2-hydroxyacid dehydrogenase homolog -
Haemophilus influenzae
Length = 331
Score = 54.4 bits (125), Expect = 3e-06
Identities = 35/129 (27%), Positives = 59/129 (45%), Gaps = 3/129 (2%)
Frame = +1
Query: 202 CAFSNSSDQRGVGRRREA---KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 372
C F N + R V + A K+V AG +N+D+ +A + G+ V+ P + + E
Sbjct: 49 CIFVNDNGSRKVLEKLAALGVKIVALRCAGFNNVDLKAAQELGIQVVRVPAYSPEAVAEH 108
Query: 373 TCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGM 552
T LM+ L R + A + + G + G+ ++G V + FGM
Sbjct: 109 TIGLMMTLNRRIHRAYQRTREANFSLEGLIGFNMYGRTVGVIGTGKIGIAVMRILKGFGM 168
Query: 553 NIIGFDPFR 579
NI+ +DPF+
Sbjct: 169 NILAYDPFK 177
>UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=7;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Silicibacter pomeroyi
Length = 313
Score = 54.0 bits (124), Expect = 3e-06
Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 1/101 (0%)
Frame = +1
Query: 259 VVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG 438
V+ G G D IDV +A +G+ V N PG +L T++L+ R + ++ G
Sbjct: 68 VIANFGVGYDAIDVAAATARGITVTNTPGVLNDDVADLAVTMLLMQCRRMEQGGAWVREG 127
Query: 439 RWDRALY-TGSELAGQDPRHPWPWRVGREVATRMYAFGMNI 558
W+ A + + +G R+GRE+A R+ AF M+I
Sbjct: 128 HWETANFPLNRKASGGVAGVVGLGRIGREIADRLAAFKMDI 168
>UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 315
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/102 (28%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+++ G G D +DV +A ++ + V + PG +L LML +AR + A +++
Sbjct: 68 EMISIMGVGYDGVDVTAALERNIRVTHTPGVLNDDVADLAIGLMLSVARRIPQADQYVRS 127
Query: 436 GRW-DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNI 558
GRW + + +++G+ R+G+ +ATR AFGM++
Sbjct: 128 GRWPEGPMPLARKVSGERLGIVGLGRIGQAIATRAEAFGMSV 169
>UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Burkholderia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia cepacia (strain ATCC 53795 /
AMMD)
Length = 320
Score = 54.0 bits (124), Expect = 3e-06
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 4/109 (3%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K++ A AG D++DV +A ++G+ V NAP A + T LML R ++A
Sbjct: 74 KIIANASAGYDHLDVAAARERGIVVSNAPDALTDCTADFTMLLMLAACRRASEYERIVRA 133
Query: 436 GRWDRAL----YTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
G W ++ G+ + G+ R+GR VA R FGM I+ D
Sbjct: 134 G-WGKSFGMTDMLGTRVNGKTLGIVGFGRIGRAVAQRARGFGMKIVYTD 181
>UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Solibacter usitatus
Ellin6076|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Solibacter usitatus (strain
Ellin6076)
Length = 312
Score = 54.0 bits (124), Expect = 3e-06
Identities = 33/102 (32%), Positives = 48/102 (47%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
++V G G D++D+ +A + GV V N PG A S E T L+ +AR + A +
Sbjct: 73 RMVSIWGTGTDHVDLAAAARHGVTVANTPGVAARSIAEHTLALLFAVARQIPHMDAATRR 132
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
G W+R EL G+ VGR A A GM ++
Sbjct: 133 GAWERG--QSMELYGKTCGVIGYGAVGRHFARLATAIGMRVM 172
>UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Klebsiella pneumoniae subsp.
pneumoniae MGH 78578|Rep: Putative D-3-phosphoglycerate
dehydrogenase - Klebsiella pneumoniae subsp. pneumoniae
MGH 78578
Length = 342
Score = 54.0 bits (124), Expect = 3e-06
Identities = 34/89 (38%), Positives = 45/89 (50%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+ A NID +A +G+ V+ PG NA +A ELT LML LARH+ + ALK
Sbjct: 68 QVIACTRANPVNIDTQAAQARGIRVLYTPGRNADAAAELTLGLMLSLARHIPQSHAALKR 127
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGRE 522
G + +A S Q R W V E
Sbjct: 128 GEFTQA-DNASAATQQGLRRDVVWDVSPE 155
>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mycobacterium sp. (strain KMS)
Length = 321
Score = 54.0 bits (124), Expect = 3e-06
Identities = 37/106 (34%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+VV G DNIDV +A GV V N PG + + T L+L + R VV L++
Sbjct: 73 RVVANVAVGYDNIDVAAAHAAGVTVTNTPGVLDNATADHTFALILAVTRRVVDGDRFLRS 132
Query: 436 GR---WDRALYTGSEL-AGQDPRHPWPWRVGREVATRMYAFGMNII 561
R W + TG ++ AG R+GR VA R AF M ++
Sbjct: 133 RRPWIWGPRMLTGLDVSAGATLGILGYGRIGRAVARRARAFDMTVL 178
>UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia
enterocolitica subsp. enterocolitica 8081|Rep: Putative
oxidoreductase - Yersinia enterocolitica serotype O:8 /
biotype 1B (strain 8081)
Length = 338
Score = 54.0 bits (124), Expect = 3e-06
Identities = 27/61 (44%), Positives = 40/61 (65%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ K++ A NIDV++A ++G+ V+ PG N+ +A ELT LML LARH+ A +AL
Sbjct: 66 QLKLIACTRANPVNIDVNAATERGIPVVYTPGRNSDAAAELTIALMLNLARHIPQAHSAL 125
Query: 430 K 432
K
Sbjct: 126 K 126
>UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4;
Mycobacterium|Rep: Glyoxylate reductase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 322
Score = 54.0 bits (124), Expect = 3e-06
Identities = 29/69 (42%), Positives = 40/69 (57%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ R ++V + GAGV+ IDV++A + G+ V N PGANA S E T LML R +
Sbjct: 66 LNRAPRLRLVHKLGAGVNTIDVETATQLGILVANMPGANAPSVAEGTVLLMLAALRRLPQ 125
Query: 415 ASTALKAGR 441
A +AGR
Sbjct: 126 LDRATRAGR 134
>UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Gloeobacter violaceus
Length = 310
Score = 53.6 bits (123), Expect = 4e-06
Identities = 31/112 (27%), Positives = 49/112 (43%)
Frame = +1
Query: 238 GRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 417
G R K + G GVDN+D +A G+ + N P ++ + + LAR
Sbjct: 67 GVRGRLKAAVKWGVGVDNVDFAAARALGIPIANTPAMFGAEVADVAVSYVTALARETFSV 126
Query: 418 STALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
++AG W + G LAG+ +G+ A R+ A M +I +DP
Sbjct: 127 DREVRAGGWPKP--CGVSLAGKTVALVGFGDIGKATARRLVAAEMRVIAYDP 176
>UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Anaeromyxobacter|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 313
Score = 53.6 bits (123), Expect = 4e-06
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 3/107 (2%)
Frame = +1
Query: 262 VGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR 441
V G GV+++D+D+ ++GV V N PG + + L+L AR VV ++AG
Sbjct: 70 VASYGVGVNHLDLDACRRRGVLVTNTPGVVTDATADHAMALLLAAARRVVEGDRVVRAGG 129
Query: 442 W---DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
W D A G+E+ G+ R+G+ A R F ++ P
Sbjct: 130 WTEVDPAWMLGTEVTGKTVGVVGFGRIGQAFARRARGFDTRVLYTSP 176
>UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15;
Bacillales|Rep: 2-hydroxyacid dehydrogenase - Bacillus
sp. SG-1
Length = 351
Score = 53.6 bits (123), Expect = 4e-06
Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
KVV G DNID+ +A +K V V N P + +LT LM+ AR ++ A ++
Sbjct: 96 KVVANLAVGFDNIDLKAANEKDVAVCNTPDVLTDTTADLTFGLMMAAARRLIEADKYVRE 155
Query: 436 GRWDRALYTGSELAGQDPRHP-----WPWRVGREVATRMYAFGMNII 561
G+W ++ +AG D H +G A R F MNI+
Sbjct: 156 GKWKS--WSPLLMAGTDIHHKTVGIIGMGSIGEAFARRAKGFDMNIL 200
>UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM
555|Rep: SerA - Clostridium kluyveri DSM 555
Length = 320
Score = 53.6 bits (123), Expect = 4e-06
Identities = 31/108 (28%), Positives = 55/108 (50%), Gaps = 1/108 (0%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
++ KV+ R G GV+N+D+ +A + + + NAP +N + E T L++ LA+
Sbjct: 63 KKLKVISRFGVGVNNVDIKTASELSIQITNAPESNKNTVAEYTMGLIIALAKKFFLYDRG 122
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATR-MYAFGMNIIGF 567
L+ G + G +L G+ +G+ +A + FGM +IGF
Sbjct: 123 LRKGNFKVRDILGIDLEGKVLGIVGLGSIGKLLALKASKGFGMKVIGF 170
>UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Glyoxylate reductase -
Thermosinus carboxydivorans Nor1
Length = 324
Score = 53.6 bits (123), Expect = 4e-06
Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+ +A G DN+D+ + ++G+ N PG + +LT L+L AR + + +
Sbjct: 70 RVIAQASVGYDNVDIAACTRRGIPFGNTPGVLVEATADLTFGLLLCAARRIHEGWNQVAS 129
Query: 436 GRW--DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
GRW + + G +L G+ R+G VA R A GM +I
Sbjct: 130 GRWLNNHDVPFGIDLYGKTLGIVGMGRIGAAVARRAKACGMKVI 173
>UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4;
Leptospira|Rep: Phosphoglycerate dehydrogenase -
Leptospira interrogans
Length = 332
Score = 53.2 bits (122), Expect = 6e-06
Identities = 26/80 (32%), Positives = 42/80 (52%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 414
+ + R K++ R G G+D++ ++ ++G+ V P A ++ ELT LM+ R V
Sbjct: 66 IHKNRNLKIISRVGIGLDSVPLNLCKERGIAVAYTPDAVTMAVAELTIGLMISSTRKVFL 125
Query: 415 ASTALKAGRWDRALYTGSEL 474
A LK G W R +TG L
Sbjct: 126 AHQELKTGGWSR--FTGKRL 143
>UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3;
Gammaproteobacteria|Rep: Glycerate dehydrogenase -
Acinetobacter sp. (strain ADP1)
Length = 318
Score = 53.2 bits (122), Expect = 6e-06
Identities = 36/113 (31%), Positives = 56/113 (49%), Gaps = 6/113 (5%)
Frame = +1
Query: 241 RRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 420
R + K++ + G +N+D+ +A +G+ V N G S + T TLML LA ++
Sbjct: 63 RLPKLKLILVSATGTNNVDLRAAKAQGIVVCNCQGYGTASVAQHTLTLMLALATSLLRYD 122
Query: 421 TALKAGRWDRAL------YTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
A+ GRW +A Y EL+G+ +G+EVA AFGM I+
Sbjct: 123 HAVAQGRWQQASQFCFLDYPIIELSGKTLGIVGYGELGKEVARLAQAFGMKIL 175
>UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=55;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 416
Score = 53.2 bits (122), Expect = 6e-06
Identities = 28/97 (28%), Positives = 49/97 (50%)
Frame = +1
Query: 280 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 459
G + +D+++A G+ V NAP +N S EL +++L R + S A G WD++
Sbjct: 86 GTNQVDLNAARMLGIPVFNAPFSNTRSVAELVMGEIVMLLRRIPSRSEACHKGGWDKSAT 145
Query: 460 TGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
E+ G+ +G +++ AFGM ++ FD
Sbjct: 146 NAWEVRGKTLGIVGYGSIGSQLSVLAEAFGMRVLYFD 182
>UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=2;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Hyphomonas neptunium
(strain ATCC 15444)
Length = 337
Score = 53.2 bits (122), Expect = 6e-06
Identities = 31/101 (30%), Positives = 51/101 (50%)
Frame = +1
Query: 259 VVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG 438
V+ R G G + +DV++A G V A G N S + +M+ + R A +A+KAG
Sbjct: 79 VISRRGVGYEKVDVEAARDLGRVVAIAAGGNDASVADQVIGMMISIGRRFQEAQSAMKAG 138
Query: 439 RWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
+W+ + G+EL + R+GR +A R+ F I+
Sbjct: 139 KWN--ILVGTELYRRKVGIVGFGRIGRSLARRLSGFEAEIL 177
>UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Salinispora arenicola
CNS205|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Salinispora arenicola
CNS205
Length = 345
Score = 53.2 bits (122), Expect = 6e-06
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Frame = +1
Query: 271 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR 450
+G GVDNID+ +A + GV V N PG E L++++ R + + G W++
Sbjct: 72 SGRGVDNIDIPAASRAGVVVANNPGLGGKPVSEHALGLLIMITRDLTAVARDAMTGAWEK 131
Query: 451 ALYTGS-ELAGQDPRHPWPWRVGREVATRMYA-FGMNIIGFDPF 576
L T EL G VG +A R A F M ++ +DP+
Sbjct: 132 RLTTRRVELTGGTLGIVGCGNVGGWMARRASAGFQMRVLAYDPY 175
>UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium efficiens|Rep: Putative uncharacterized
protein - Corynebacterium efficiens
Length = 161
Score = 52.8 bits (121), Expect = 8e-06
Identities = 38/101 (37%), Positives = 42/101 (41%)
Frame = -2
Query: 479 PASSLPVYRARSHLPAFSAVEAGTTWRARTNINVQVSSHALSALAPGALITPTPFLPAES 300
P S P+ R H P+ A WRA S A L GAL T TP A
Sbjct: 12 PKISTPLKEERFHSPSRRVASAAGIWRAVDRSRETACSQAEWMLEVGALATMTPASVAAG 71
Query: 299 TSMLSTPAPARPTTFASRLRPTPLWSLELLNAQPERRGWVS 177
S LS P PARPT F RL + S L A+ RR S
Sbjct: 72 MSTLSRPTPARPTIF--RLGAAAMTSASTLVAERTRRASAS 110
>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
- Rhodopirellula baltica
Length = 406
Score = 52.8 bits (121), Expect = 8e-06
Identities = 32/105 (30%), Positives = 53/105 (50%), Gaps = 4/105 (3%)
Frame = +1
Query: 259 VVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG 438
VV G +NIDVD+A +GV V N P + +L +L+ +RHV+PA ++ G
Sbjct: 156 VVSNYAVGFNNIDVDAAKTRGVVVGNTPDVLTDATADLAVSLLFAASRHVLPAGNQVREG 215
Query: 439 R---WDRALYTGSELAGQDPRHPWPWRVGREVATRMY-AFGMNII 561
W+ + G E + + R+G+ A R+ +GMN++
Sbjct: 216 EWKTWEPTGWLGVEPSDKTLGIVGMGRIGKATAKRLVGGWGMNLL 260
>UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillus
subtilis
Length = 344
Score = 52.8 bits (121), Expect = 8e-06
Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 6/115 (5%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
E VG N+DV +A K+G+ V PG NA + E+ ++ RH ++ L
Sbjct: 81 ELSFVGVCRGMPSNVDVAAASKRGIPVFYTPGRNAQAVAEMFIGNVISFLRHTSASNQWL 140
Query: 430 KAGRWDR------ALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
K G WD + G+EL G+ VG+ +A + AF I +DP+
Sbjct: 141 KDGEWDSDYLQAYVKFKGNELTGKTVGMIGFGAVGQRIAKLLTAFDCKIKYYDPY 195
>UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic domain:D- isomer specific
2-hydroxyacid dehydrogenase, NAD binding domain; n=1;
Azotobacter vinelandii AvOP|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic domain:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD binding domain
- Azotobacter vinelandii AvOP
Length = 319
Score = 52.8 bits (121), Expect = 8e-06
Identities = 24/57 (42%), Positives = 36/57 (63%)
Frame = +1
Query: 274 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW 444
G+G D ID+D A ++G+ V N+P ANA S +L L++ R++ A L+AGRW
Sbjct: 77 GSGYDGIDLDHARQRGIVVTNSPAANAASVADLAMGLLISSVRNLPAARQYLEAGRW 133
>UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase
protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
phosphoglycerate dehydrogenase protein - Fulvimarina
pelagi HTCC2506
Length = 322
Score = 52.8 bits (121), Expect = 8e-06
Identities = 35/102 (34%), Positives = 51/102 (50%), Gaps = 4/102 (3%)
Frame = +1
Query: 268 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 447
R GAG+D I V +A + G+ V N P NA S E L++ LAR +V ++ W
Sbjct: 64 RHGAGLDFIPVQAASRLGIAVTNTPSVNAKSVAEHVFGLIICLARRIVENDAGIRRNEWH 123
Query: 448 --RALYTGS-ELAGQDPRHPWPWRVGREVA-TRMYAFGMNII 561
RA GS E+AG+ +G+ +A FGMN++
Sbjct: 124 ALRAAAPGSCEIAGKALGLIGYGGIGQAIAQIGKLGFGMNVL 165
>UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidiphilium cryptum
JF-5|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidiphilium cryptum (strain JF-5)
Length = 328
Score = 52.8 bits (121), Expect = 8e-06
Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 2/138 (1%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ ++V R G G D++DV + + + + N+ S E ++L LAR + A
Sbjct: 64 QLRIVSRHGVGYDSVDVPALNARRIPLSLVGDVNSRSVAEHALMMILALARRLPDYDRAT 123
Query: 430 KAGRWDRA-LYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPFRVC*SVRPV- 603
+AG W R ++AG+ R+GR VA AF M ++ DP ++R
Sbjct: 124 RAGEWHRRDSREAGDIAGKSLLVIGFGRIGRIVAKMAQAFEMQVMVRDPMADPAAIRDAG 183
Query: 604 PLHQDGAGGHLASSGSTS 657
+ D GG LA++ S
Sbjct: 184 AVPADDLGGALAAADFVS 201
>UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=3; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 594
Score = 52.8 bits (121), Expect = 8e-06
Identities = 37/111 (33%), Positives = 55/111 (49%), Gaps = 4/111 (3%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K + + G GVD ID+ +A K G+ V+N PG NA + EL +ML LAR ++
Sbjct: 100 KYISKQGTGVDKIDIVNAKKLGIPVMNTPGVNAQAVAELAFGMMLSLARQTPSIDRKIRK 159
Query: 436 GRWDRAL--YTGSELAGQDPRHPWPWRVGREVATRMY--AFGMNIIGFDPF 576
G L + G L G+ +G VA +M+ AF I+ +DP+
Sbjct: 160 GASVTKLDGWKGQMLYGKTLGVIGGGNIGLLVA-KMFAGAFSGKIVLYDPY 209
>UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72;
Alphaproteobacteria|Rep: Gluconate 2-dehydrogenase -
Brucella melitensis
Length = 360
Score = 52.4 bits (120), Expect = 1e-05
Identities = 32/106 (30%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL-- 429
K++ G GVDNIDV +A ++G+ V N P ++T L+L + R +V + +
Sbjct: 100 KLIANFGNGVDNIDVAAAARRGITVTNTPNVLTEDTADMTLALLLSVPRRLVEGANVINE 159
Query: 430 KAGR---WDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNI 558
+ G+ W G + G+ R+G VA R AFG++I
Sbjct: 160 RHGQWPGWSPTWMLGRRIWGKRLGIVGMGRIGTAVARRAKAFGLSI 205
>UniRef50_Q1R7K3 Cluster: 2-hydroxyacid dehydrogenase; n=7;
Enterobacteriaceae|Rep: 2-hydroxyacid dehydrogenase -
Escherichia coli (strain UTI89 / UPEC)
Length = 318
Score = 52.4 bits (120), Expect = 1e-05
Identities = 29/105 (27%), Positives = 54/105 (51%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+++ R G G+DNID+ +A + G+ V NA G N+ + E L+ R++ + A++
Sbjct: 75 RIISRFGTGIDNIDLRAAQQSGIVVNNAVGINSNAVAEFIIGLIFASMRNIPGSYHAMQN 134
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
G W + EL G+ +G+ +A R+ F + ++ FD
Sbjct: 135 GYWGESHV--CELQGKRIGLVGYGNIGKTLAKRLSGFDVELLAFD 177
>UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Clostridium
beijerinckii NCIMB 8052
Length = 320
Score = 52.4 bits (120), Expect = 1e-05
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 1/106 (0%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
++ K+V + GAG DN+D+D+ + G+ NA G NA + E L+L +++ +
Sbjct: 68 KKLKLV-QTGAGFDNVDIDACTQYGIWAANAAGVNAQAVAEHVMALILSYYKNIPFLDSF 126
Query: 427 LKAGRWDRAL-YTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
+K + L YTGSEL G+ VG++VA F MNI+
Sbjct: 127 IKNKIDENELQYTGSELKGKTIGIIGFGAVGKKVAEFCRVFDMNIL 172
>UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2;
Filobasidiella neoformans|Rep: Phosphoglycerate
dehydrogenase - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 316
Score = 52.4 bits (120), Expect = 1e-05
Identities = 27/66 (40%), Positives = 39/66 (59%), Gaps = 2/66 (3%)
Frame = +1
Query: 247 REAKVVGRA--GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 420
+E K++G A G G D+ID++ +KGV ++N PG N+ ELT +L L L R V
Sbjct: 97 KEGKLMGLAIVGVGYDSIDIEGCKEKGVTLMNCPGENSQVVAELTLSLTLALLRRVPELD 156
Query: 421 TALKAG 438
L+AG
Sbjct: 157 RRLRAG 162
>UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG08018.1 - Gibberella zeae PH-1
Length = 901
Score = 52.0 bits (119), Expect = 1e-05
Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 2/107 (1%)
Frame = +1
Query: 262 VGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG- 438
+G+ G G+D IDVD+ +G+ + N PG NA + EL TL AR V +G
Sbjct: 82 IGKQGVGLDKIDVDACASRGIKIFNTPGVNARAVAELVLTLATASARQVGSIIAKQSSGI 141
Query: 439 RWDRALYTGSELAGQDPRHPWPWRVGREVATRMY-AFGMNIIGFDPF 576
+ +G L + +G+ VA AF N+I +DPF
Sbjct: 142 LVPKEKCSGLILHEKTIGILGMGNIGKCVAKIFRGAFDANVIAYDPF 188
>UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1;
Oceanobacillus iheyensis|Rep: 2-ketogluconate reductase
- Oceanobacillus iheyensis
Length = 324
Score = 52.0 bits (119), Expect = 1e-05
Identities = 40/158 (25%), Positives = 64/158 (40%), Gaps = 9/158 (5%)
Frame = +1
Query: 115 QRLRNR---HHHQGQDLQGRTSYGDTQPRRSGCAFSNSSDQRGVGRRREAKVVGRAGAGV 285
++L+NR H HQ + + + D Q D + + K+V G
Sbjct: 17 EQLKNRFIVHQHQLKSEMDDSFFSDLQRVEGIIGSKLRVDGHLLDQAPHLKIVTNISVGY 76
Query: 286 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 465
DN++++ K+G+ N P + + L+L +R + +K GRWD + G
Sbjct: 77 DNLEIEELTKRGIMATNTPDVLTDTVADTVFGLLLATSRRICELDQYVKLGRWDENI--G 134
Query: 466 SELAGQDPRHP-----WPWRVGREVATRM-YAFGMNII 561
L G D H R+G VA R Y F M I+
Sbjct: 135 EHLFGVDVHHKTLGIIGMGRIGLAVAERAHYGFKMKIV 172
>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
acidophilus|Rep: Glyoxylate reductase - Lactobacillus
acidophilus
Length = 321
Score = 52.0 bits (119), Expect = 1e-05
Identities = 35/116 (30%), Positives = 55/116 (47%), Gaps = 3/116 (2%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ + + KV+ G G D+ID+D A +KG+ V N P + EL T+++ AR
Sbjct: 60 DKEIIDAAKNLKVISTYGVGFDHIDIDYAREKGIVVTNCPNSVLRPTAELALTMIMASAR 119
Query: 403 HVVPASTALKAGRW---DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
+ AL+ G + D G + G+ R+G++VA A GM II
Sbjct: 120 RIRYYDHALREGVFLNVDEYDSQGYTIEGKTLGILGMGRIGQQVARFAKALGMKII 175
>UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer
specific; n=1; Syntrophus aciditrophicus SB|Rep:
2-hydroxyacid dehydrogenase, D-isomer specific -
Syntrophus aciditrophicus (strain SB)
Length = 326
Score = 52.0 bits (119), Expect = 1e-05
Identities = 28/105 (26%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+G G++++ + S +G+ ++N G + +L TL+L L R V +++
Sbjct: 83 RVIGTYSVGINHLPITSCQSRGIRIVNTQGVLTDATADLALTLLLSLTRRVREGEALVRS 142
Query: 436 GRWD---RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
G W L G+ L G+ +GR A R++A GM +I
Sbjct: 143 GHWKGWAPDLLLGTGLTGKTCGILGSGPIGRAFARRVWAIGMKVI 187
>UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 727
Score = 52.0 bits (119), Expect = 1e-05
Identities = 43/114 (37%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR----HVVPAST 423
KVV R G G+DNIDV +A + G+ V +APG + T +L+L L R H S
Sbjct: 244 KVVFRIGYGIDNIDVKAATELGIAVCHAPGDYVEDVADSTLSLILDLFRRTYWHAKSYSE 303
Query: 424 ALKAGRWD--RALYTGS-ELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
K D R GS ++ G RVG V R AFG++II +DPF
Sbjct: 304 TRKTIGADQVRENAVGSKKVRGSVLGILGCGRVGTAVGLRARAFGLHIIFYDPF 357
>UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 743
Score = 52.0 bits (119), Expect = 1e-05
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 1/106 (0%)
Frame = +1
Query: 262 VGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR 441
+G+ G G++ ID D+ K+G+ ++N PGANA EL TL L +AR + +T +
Sbjct: 501 IGKHGVGIEKIDQDACVKRGIKILNTPGANARDVAELVVTLALSVARGIRSITTRQMSKP 560
Query: 442 WDRALYTGSELAGQDPRHPWPWRVGREVATRMY-AFGMNIIGFDPF 576
+ G L + +GR VA F +I+ +D +
Sbjct: 561 VPKETCNGLTLYQKTIGIIGMGNIGRTVAEIFRGGFAADIVAYDAY 606
>UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; n=1;
Gibberella zeae PH-1|Rep: hypothetical protein FG00146.1
- Gibberella zeae PH-1
Length = 1068
Score = 51.6 bits (118), Expect = 2e-05
Identities = 34/113 (30%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV--VPAST 423
+ +V+G+ G G+D IDV++ + V V N PG NA + E+T L L +AR V V
Sbjct: 812 QLRVIGKQGVGLDKIDVEACKRHNVKVCNTPGVNASAVAEMTLCLALTVAREVPDVVIRQ 871
Query: 424 ALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGM--NIIGFDPF 576
++ + G L+ + +G+ +A +M+ G+ II FDP+
Sbjct: 872 KIQGEAIRKETVAGMLLSRKIIGVVGMGHIGQAIA-QMFVGGLQAEIIAFDPY 923
>UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Rep:
Ribeye a protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 1147
Score = 51.6 bits (118), Expect = 2e-05
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 7/114 (6%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+++ R G+G DNID+ +AG+ G+ V N P A + T +L L R A++
Sbjct: 842 RIIIRIGSGYDNIDIKAAGEMGIAVCNIPSAAVEETADSTLCHILNLYRRNTWLYQAMRE 901
Query: 436 GRWDRALYTGSELAGQDPRHPWP-------WRVGREVATRMYAFGMNIIGFDPF 576
G +++ E+A R R G+ VA R AFG N+I +DP+
Sbjct: 902 GTRVQSVEQIREVASGAARIRGETLGLIGFGRSGQAVAVRAKAFGFNVIFYDPY 955
>UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8;
Bacillaceae|Rep: Glycerate dehydrogenase - Bacillus
halodurans
Length = 324
Score = 51.6 bits (118), Expect = 2e-05
Identities = 35/124 (28%), Positives = 57/124 (45%), Gaps = 6/124 (4%)
Frame = +1
Query: 208 FSNSSDQRGVG---RRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 378
F+N +D+ V R + KVV G DNID+ A K+GV V + PG + +LT
Sbjct: 49 FTNLTDRFDVEAFERAKRLKVVSTMAVGYDNIDIKEATKRGVSVGHTPGVLTEATADLTF 108
Query: 379 TLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGQDPRHPWPWRVGREVATRMYAFG 549
L++ R + + ++ +W + TG + G R+G+ VA R F
Sbjct: 109 ALLMATGRRLRESIDYVRNDQWKSWGPFMLTGQAIYGTTLGIIGMGRIGQAVAKRAKGFN 168
Query: 550 MNII 561
M ++
Sbjct: 169 MTLL 172
>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Clostridium|Rep: 2-hydroxyacid dehydrogenase -
Clostridium tetani
Length = 357
Score = 51.6 bits (118), Expect = 2e-05
Identities = 31/105 (29%), Positives = 57/105 (54%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K++ A G+D+I++++ K + V N+ G + S ELT L+L L R++VP + ++
Sbjct: 112 KMISVAFTGIDHINMETCRKNNIMVCNSAGYSTSSVVELTFGLILSLLRNIVPLNDEVRN 171
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
G + Y+ +LAG+ +G EV AFG N++ ++
Sbjct: 172 GNTKQG-YSQYDLAGKTLGVIGAGDIGTEVIRIGKAFGCNVLVYN 215
>UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=1; Lactobacillus delbrueckii subsp.
bulgaricus ATCC 11842|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Lactobacillus delbrueckii
subsp. bulgaricus (strain ATCC 11842 / DSM20081)
Length = 322
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/119 (31%), Positives = 58/119 (48%), Gaps = 6/119 (5%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
DQ + ++ K+V G G D+IDVD A +G+ V N P + E+ TL+L L+R
Sbjct: 61 DQELLDAGKKLKIVSATGVGYDHIDVDYASSQGIIVSNCPASVMQPTAEMAFTLLLALSR 120
Query: 403 HVVPASTALKAGRWDRALYTG-SELAGQDPRHP-----WPWRVGREVATRMYAFGMNII 561
+ + + R + L TG E GQ P R+G+ +A+ FGMNI+
Sbjct: 121 KLALYNQEM---RQENFLDTGLLENQGQSPVGKTLGIFGMGRIGKTLASYARTFGMNIL 176
>UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Oceanicaulis alexandrii HTCC2633
Length = 407
Score = 51.6 bits (118), Expect = 2e-05
Identities = 29/108 (26%), Positives = 54/108 (50%)
Frame = +1
Query: 247 REAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 426
+E + VG G + +D+ +A ++GV V NAP AN S ELT +++L R + A
Sbjct: 70 KELQAVGCFCIGTNQVDLVAAAERGVPVFNAPFANTRSVAELTMASVIMLMRRIPEKMFA 129
Query: 427 LKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
++ G W + +E+ + +G +++ A GM++ +D
Sbjct: 130 IQRGEWLKTADGANEVRKKKLGIIGYGNIGAQLSVIASALGMHVYYYD 177
>UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 454
Score = 51.6 bits (118), Expect = 2e-05
Identities = 37/118 (31%), Positives = 55/118 (46%), Gaps = 16/118 (13%)
Frame = +1
Query: 268 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT-CTLMLVLA------RHVVPASTA 426
R GAG +NI V + G+ V N PGANA + EL C+L+L +HV
Sbjct: 87 RCGAGTNNIPVKEMSELGIPVFNTPGANANAVKELVVCSLLLASRGIIEGNKHVNDVINV 146
Query: 427 LKAGRW---------DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
+ G + D+A++ G+E+ G+ +G V GMN+IG+DP
Sbjct: 147 EENGDYAKISVRIEKDKAMFGGTEIEGKTLGVIGLGAIGSRVVNAALGLGMNVIGYDP 204
>UniRef50_A4R4W0 Cluster: Formate dehydrogenase; n=1; Magnaporthe
grisea|Rep: Formate dehydrogenase - Magnaporthe grisea
(Rice blast fungus) (Pyricularia grisea)
Length = 364
Score = 51.6 bits (118), Expect = 2e-05
Identities = 26/75 (34%), Positives = 42/75 (56%), Gaps = 2/75 (2%)
Frame = +1
Query: 235 VGRRREAKVVGRAGAGVDNIDVDSAGKK--GVGVINAPGANALSACELTCTLMLVLARHV 408
+ R ++ K+ AG G D++D+++A K G+ V G+N +S E +LVL R+
Sbjct: 150 LARAKKLKLTVTAGIGSDHVDLNAANKTNGGITVAEVTGSNVVSVAEHVLMTILVLVRNF 209
Query: 409 VPASTALKAGRWDRA 453
VPA ++ G WD A
Sbjct: 210 VPALEMIQTGEWDVA 224
>UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3;
Mesorhizobium loti|Rep: Phosphoglycerate dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 341
Score = 51.2 bits (117), Expect = 2e-05
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 2/111 (1%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPG-ANALSACELTCTLMLVLARHV-VPAST 423
+ + + + G GVD+ID+D+A + G+ V + P + E LML +A+ +
Sbjct: 79 DLRYISKYGIGVDSIDIDAATEHGILVSSTPNDFQIFTVSEHAVALMLAVAKQLGTWTPE 138
Query: 424 ALKAGRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDPF 576
++ G W R L G+ L G R+GR VA R+ + I+ +DPF
Sbjct: 139 FMRRGGW-RGLTHGATLRGATVGIVGLGRIGRGVAQRLSGWEARILAYDPF 188
>UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Rep:
Blr3173 protein - Bradyrhizobium japonicum
Length = 360
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Frame = +1
Query: 259 VVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAG 438
+V GAG D +DV++ GV V+N G NA S E +ML L++ ++ + L+
Sbjct: 92 LVSSNGAGFDPVDVEACTDAGVLVVNQSGGNAHSVAEHALAMMLTLSKRIIQSDRRLRRE 151
Query: 439 R-WDRALYTGSELAGQDPRHPWPWRVGREVATRMYA-FGMNIIGFDPF 576
R +R G+E+ + VGR +A GM ++ +DP+
Sbjct: 152 RDVNRNDLVGNEVEHKTVGIIGLGNVGRRIAALCNGLLGMKVLAYDPY 199
>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
protein; n=10; cellular organisms|Rep:
D-3-phosphoglycerate dehydrogenase-like protein -
Leishmania major
Length = 511
Score = 51.2 bits (117), Expect = 2e-05
Identities = 28/97 (28%), Positives = 47/97 (48%)
Frame = +1
Query: 280 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 459
G + +D+D A +GV V N+P AN S EL ++ L+R + S + G W++
Sbjct: 186 GTNQVDLDYATTRGVAVFNSPFANTRSVAELVIGEIISLSRKMTQRSEEVHRGVWNKTHV 245
Query: 460 TGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFD 570
E+ G+ +G +V A GMN++ +D
Sbjct: 246 GCYEVRGKTVGIVGYGHIGSQVGVLAEALGMNVVFYD 282
Score = 34.7 bits (76), Expect = 2.2
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Frame = +2
Query: 74 LIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 250
L+++GV ELL + G I + ++ LL +I + L +RS TQVT+ +LDA
Sbjct: 116 LLLEGVNPIAKELLESKGCIVEYIPNALPRDTLLEKIRDVHFLGIRSKTQVTQAILDAAP 175
Query: 251 K 253
K
Sbjct: 176 K 176
>UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n=2;
Eukaryota|Rep: Glycerate dehydrogenase-like protein -
Trimastix pyriformis
Length = 232
Score = 51.2 bits (117), Expect = 2e-05
Identities = 34/105 (32%), Positives = 51/105 (48%), Gaps = 3/105 (2%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+VV G +NID+ +A ++ V V N P A + +LT L+L +AR +V ++A
Sbjct: 68 RVVANYAVGYNNIDLTAANERHVVVTNTPHCLAEATADLTMGLLLAVARRLVEGDGLVRA 127
Query: 436 G---RWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
G W G +L G+ +G VA R AFGM I+
Sbjct: 128 GLFKGWAPEFLLGMDLHGKTLGIIGLGEIGTCVARRARAFGMRIV 172
>UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98;
Coelomata|Rep: C-terminal-binding protein 2 - Homo
sapiens (Human)
Length = 445
Score = 51.2 bits (117), Expect = 2e-05
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 7/114 (6%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+V+ R G+G DN+D+ +AG+ G+ V N P A + T +L L R AL+
Sbjct: 99 RVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALRE 158
Query: 436 GRWDRALYTGSELAGQDPRHPWP-------WRVGREVATRMYAFGMNIIGFDPF 576
G +++ E+A R R G+ VA R AFG ++I +DP+
Sbjct: 159 GTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPY 212
>UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2;
Actinomycetales|Rep: Glyoxylate reductase - Arthrobacter
aurescens (strain TC1)
Length = 329
Score = 50.8 bits (116), Expect = 3e-05
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 3/109 (2%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K V G +NIDVD+A + G+ V N PG + ++ L+L AR VV + ++
Sbjct: 68 KGVSNYAVGYNNIDVDAATRHGILVGNTPGVLTDATADVAMLLILGTARRVVESDRVVRD 127
Query: 436 GR---WDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
G+ W+ G +++G R+ R VA R FGM + F P
Sbjct: 128 GKFLGWEPEFMLGRDVSGAVLGLAGFGRIARAVARRALGFGMEEL-FSP 175
>UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Burkholderia
phytofirmans PsJN|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 274
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/108 (27%), Positives = 55/108 (50%), Gaps = 6/108 (5%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
+++G AGV+++D ++ K+G+G++ PG + +S E LML L R+++P + A
Sbjct: 30 ELIGVPAAGVNHLDTETCRKRGIGIVACPGYSTISVPEHAFALMLALRRNLMPYWHDVYA 89
Query: 436 GRWDRA------LYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
G W + L+ +L G G+ +A AFGM ++
Sbjct: 90 GGWSGSPTFYAELHPIQDLHGSTLGIVGAGHGGKRLAELARAFGMRVL 137
>UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;
Trichocomaceae|Rep: Contig An11c0250, complete genome -
Aspergillus niger
Length = 336
Score = 50.8 bits (116), Expect = 3e-05
Identities = 31/102 (30%), Positives = 50/102 (49%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
K + GAG D ID ++ K+G+ V NAP + +L L+L R++ PA +L A
Sbjct: 81 KYIFHNGAGYDPIDTEACAKRGIIVTNAPDPVTDATADLAVLLLLGALRNLNPAIRSLYA 140
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNII 561
G + + + G + G+ R+GR V R FG+ +
Sbjct: 141 GTFKQGVGFGHDPQGKTLGILGMGRIGRAVKQRCEPFGIKTV 182
>UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular
organisms|Rep: Dehydrogenase - Oceanobacillus iheyensis
Length = 329
Score = 50.4 bits (115), Expect = 4e-05
Identities = 32/112 (28%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Frame = +1
Query: 250 EAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 429
+ K+V R G GVDN+D+ +A + GV V N P + +ML R + ++ +
Sbjct: 68 DLKLVVRYGVGVDNVDIAAATEHGVQVCNVPDYGMNEVADQALAMMLNFTRSISRMNSFV 127
Query: 430 KAGRWD----RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
+ G WD LY SE Q R+G A ++ + G ++ +DP
Sbjct: 128 RKGVWDYQKSMPLYRHSE---QTVGVIGVGRIGSSFAKKVKSLGCRVVAYDP 176
>UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-phosphoglycerate
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 321
Score = 50.4 bits (115), Expect = 4e-05
Identities = 27/99 (27%), Positives = 47/99 (47%)
Frame = +1
Query: 268 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 447
RAG+G+DN+D+D + ++ P A + EL +ML L+R ++ A L+ G W
Sbjct: 68 RAGSGLDNVDLDYLRNHDLKLVRIPQPGARAVAELAFGMMLALSRQILVADQLLRKGTWA 127
Query: 448 RALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIG 564
+ G L + +G + A+GM ++G
Sbjct: 128 KHQLRGHLLVNKQLGIVGLGNIGTLLGQMGLAWGMQVLG 166
>UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n=9;
Streptococcus|Rep: Glyoxylate reductase, NADH-dependent
- Streptococcus agalactiae 515
Length = 318
Score = 50.4 bits (115), Expect = 4e-05
Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 3/123 (2%)
Frame = +1
Query: 223 DQRGVGRRREAKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 402
D+ + +++ G D++D A +KG+ V N+P A + E+T L+L ++
Sbjct: 57 DKEMIDAGENLQIISLNAVGFDHVDTAYAKEKGIIVSNSPQAVRVPTAEMTFALILAASK 116
Query: 403 HVVPASTALKAGRW---DRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNIIGFDP 573
+ + +++G W Y G L G R+G VA AFGM ++ D
Sbjct: 117 RLAFYDSIVRSGEWIDPSEQRYQGLTLQGSTLGIYGMGRIGLTVANFAKAFGMTVVYNDV 176
Query: 574 FRV 582
+R+
Sbjct: 177 YRL 179
>UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ralstonia metallidurans
CH34|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Ralstonia metallidurans (strain CH34 /
ATCC 43123 / DSM 2839)
Length = 317
Score = 50.4 bits (115), Expect = 4e-05
Identities = 29/101 (28%), Positives = 48/101 (47%)
Frame = +1
Query: 256 KVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA 435
++V GAG +NI+ D+A +GV V +AP N+ + +ML +R + LKA
Sbjct: 71 ELVASFGAGYENIERDAARMRGVRVCHAPDTNSQVVADHALAMMLAWSRGIAMLDRGLKA 130
Query: 436 GRWDRALYTGSELAGQDPRHPWPWRVGREVATRMYAFGMNI 558
G+WD + G+ +G+ +A A GM +
Sbjct: 131 GQWDALRAPRPGVRGKTLGIVGLGNIGQRLAALAEAVGMRV 171
>UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8;
Bradyrhizobiaceae|Rep: 2-hydroxyacid dehydrogenase -
Bradyrhizobium japonicum
Length = 317
Score = 50.0 bits (114), Expect = 5e-05
Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Frame = +1
Query: 274 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW--D 447
G G D +D+ +A + + V ++PGANA S ++ TLML R ++ A +++G W
Sbjct: 74 GTGYDGVDLKAAAARDIAVGHSPGANAASVADIAMTLMLATTRRILVADQYVRSGDWAAS 133
Query: 448 RALYTGSELAGQDPRHPWPW---RVGREVATRMYAF 546
+ AG R + +GR++A R AF
Sbjct: 134 KPSPMMRPQAGMPGRRIGVYGMGEIGRKIAARCAAF 169
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 764,876,423
Number of Sequences: 1657284
Number of extensions: 17555526
Number of successful extensions: 89213
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 76168
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 88379
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 55371905986
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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