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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= prgv0266
         (693 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q4S8W6 Cluster: Ribonucleoside-diphosphate reductase; n...   163   4e-39
UniRef50_P07742 Cluster: Ribonucleoside-diphosphate reductase la...   153   5e-36
UniRef50_P23921 Cluster: Ribonucleoside-diphosphate reductase la...   149   5e-35
UniRef50_Q01H73 Cluster: Ribonucleoside-diphosphate reductase; n...   141   1e-32
UniRef50_Q9SJ20 Cluster: Ribonucleoside-diphosphate reductase la...   136   4e-31
UniRef50_Q8JKL8 Cluster: Ribonucleoside-diphosphate reductase; n...   133   4e-30
UniRef50_O12935 Cluster: Ribonucleoside-diphosphate reductase; n...   128   2e-28
UniRef50_Q75BW6 Cluster: Ribonucleoside-diphosphate reductase; n...   118   2e-25
UniRef50_Q9QAL9 Cluster: Ribonucleoside-diphosphate reductase; n...   109   5e-23
UniRef50_Q7T6Y8 Cluster: Ribonucleoside-diphosphate reductase la...   100   3e-20
UniRef50_Q6MLM3 Cluster: Ribonucleoside-diphosphate reductase al...    96   8e-19
UniRef50_P26685 Cluster: Ribonucleoside-diphosphate reductase la...    93   4e-18
UniRef50_O41111 Cluster: Ribonucleoside-diphosphate reductase; n...    93   6e-18
UniRef50_A7IY07 Cluster: Putative uncharacterized protein B832R;...    88   2e-16
UniRef50_Q4J4L6 Cluster: Ribonucleoside-diphosphate reductase; n...    88   2e-16
UniRef50_Q9HMU3 Cluster: Ribonucleoside-diphosphate reductase; n...    85   2e-15
UniRef50_Q3AEA3 Cluster: Ribonucleoside-diphosphate reductase, a...    84   4e-15
UniRef50_O84834 Cluster: Ribonucleoside-diphosphate reductase su...    83   5e-15
UniRef50_Q67KQ2 Cluster: Ribonucleoside-diphosphate reductase; n...    78   2e-13
UniRef50_A2XAQ8 Cluster: Ribonucleoside-diphosphate reductase; n...    78   2e-13
UniRef50_Q39JT6 Cluster: Ribonucleoside-diphosphate reductase; n...    78   2e-13
UniRef50_Q3E5I1 Cluster: Ribonucleoside-diphosphate reductase; n...    77   5e-13
UniRef50_P74911 Cluster: Ribonucleoside-diphosphate reductase; n...    76   1e-12
UniRef50_UPI0000F5175D Cluster: hypothetical protein Faci_030006...    75   1e-12
UniRef50_Q8R7R2 Cluster: Ribonucleoside-diphosphate reductase; n...    75   2e-12
UniRef50_Q6A5Y5 Cluster: Ribonucleoside-diphosphate reductase al...    75   2e-12
UniRef50_A4L245 Cluster: Ribonucleotide reductase large subunit;...    74   4e-12
UniRef50_Q8TQ86 Cluster: Ribonucleoside-diphosphate reductase; n...    73   5e-12
UniRef50_Q6R7H4 Cluster: Ribonucleoside-diphosphate reductase; n...    73   9e-12
UniRef50_Q6UDJ2 Cluster: Ribonucleoside-diphosphate reductase; n...    71   2e-11
UniRef50_Q91ES8 Cluster: ORF127 RR1; n=1; Cydia pomonella granul...    71   3e-11
UniRef50_A2DI13 Cluster: Ribonucleoside-diphosphate reductase; n...    71   3e-11
UniRef50_A6QCU9 Cluster: Ribonucleoside-diphosphate reductase, a...    70   6e-11
UniRef50_O26748 Cluster: Ribonucleoside-diphosphate reductase; n...    70   6e-11
UniRef50_Q67SN6 Cluster: Ribonucleoside-diphosphate reductase; n...    69   1e-10
UniRef50_A0RYG3 Cluster: Ribonucleoside-diphosphate reductase; n...    69   1e-10
UniRef50_P55982 Cluster: Ribonucleoside-diphosphate reductase su...    69   1e-10
UniRef50_Q647Z9 Cluster: Ribonucleoside-diphosphate reductase; n...    69   1e-10
UniRef50_Q6QXF6 Cluster: ORF37; n=4; Baculoviridae|Rep: ORF37 - ...    68   2e-10
UniRef50_Q6AJC4 Cluster: Ribonucleoside-diphosphate reductase; n...    68   2e-10
UniRef50_Q6VMN2 Cluster: Ribonucleoside-diphosphate reductase; n...    67   3e-10
UniRef50_A5FSC1 Cluster: Ribonucleoside-diphosphate reductase, a...    67   4e-10
UniRef50_Q9UYA0 Cluster: Ribonucleoside-diphosphate reductase; n...    67   4e-10
UniRef50_P95484 Cluster: Ribonucleoside-diphosphate reductase; n...    67   4e-10
UniRef50_A3QTY4 Cluster: Ribonucleotide reductase large subunit;...    66   1e-09
UniRef50_Q8VKI9 Cluster: Ribonucleoside-diphosphate reductase; n...    65   1e-09
UniRef50_O83972 Cluster: Ribonucleoside-diphosphate reductase su...    65   1e-09
UniRef50_O66503 Cluster: Ribonucleoside-diphosphate reductase su...    65   1e-09
UniRef50_Q2VSI0 Cluster: Ribonucleoside-diphosphate reductase; n...    64   4e-09
UniRef50_Q5KX82 Cluster: Ribonucleoside-diphosphate reductase; n...    64   4e-09
UniRef50_A0B8R8 Cluster: Ribonucleoside-diphosphate reductase; n...    63   5e-09
UniRef50_P74240 Cluster: Ribonucleoside-diphosphate reductase su...    63   7e-09
UniRef50_Q18UV0 Cluster: Ribonucleoside-diphosphate reductase; n...    62   9e-09
UniRef50_Q4C9K9 Cluster: Ribonucleoside-diphosphate reductase; n...    62   1e-08
UniRef50_Q97ZH9 Cluster: Ribonucleoside-diphosphate reductase; n...    62   1e-08
UniRef50_UPI00015BC77F Cluster: UPI00015BC77F related cluster; n...    62   2e-08
UniRef50_Q5SM68 Cluster: Ribonucleoside-diphosphate reductase; n...    60   4e-08
UniRef50_A5TVY2 Cluster: Ribonucleoside-diphosphate reductase; n...    60   4e-08
UniRef50_Q9IBT4 Cluster: Ribonucleoside-diphosphate reductase; n...    59   9e-08
UniRef50_Q5LNK9 Cluster: Ribonucleoside-diphosphate reductase, p...    59   1e-07
UniRef50_A3H704 Cluster: Ribonucleoside-diphosphate reductase; n...    59   1e-07
UniRef50_A3JKM6 Cluster: Ribonucleoside reductase; n=1; Marinoba...    58   2e-07
UniRef50_Q9PE32 Cluster: Ribonucleoside-diphosphate reductase; n...    58   3e-07
UniRef50_A1YJD3 Cluster: Ribonucleoside-diphosphate reductase; n...    57   4e-07
UniRef50_O33839 Cluster: Ribonucleoside-diphosphate reductase; n...    57   4e-07
UniRef50_A7I485 Cluster: Ribonucleoside-diphosphate reductase, a...    57   4e-07
UniRef50_Q5P1D5 Cluster: Ribonucleotide reductase, Coenzyme B12-...    56   6e-07
UniRef50_Q2RP92 Cluster: Ribonucleotide reductase large subunit;...    56   6e-07
UniRef50_A6NX38 Cluster: Ribonucleoside-diphosphate reductase; n...    56   6e-07
UniRef50_Q9YA77 Cluster: Ribonucleoside-diphosphate reductase; n...    56   6e-07
UniRef50_P09853 Cluster: Ribonucleoside-diphosphate reductase la...    56   6e-07
UniRef50_A7KUZ9 Cluster: Nrd alpha subunit; n=1; Bacillus phage ...    56   8e-07
UniRef50_A7HK53 Cluster: Ribonucleoside-diphosphate reductase, a...    56   1e-06
UniRef50_Q9RZL7 Cluster: Ribonucleoside-diphosphate reductase; n...    55   1e-06
UniRef50_Q21U31 Cluster: Ribonucleoside-diphosphate reductase; n...    55   1e-06
UniRef50_A7IYE5 Cluster: Putivate ribonucleotide reductase; n=1;...    55   1e-06
UniRef50_Q89YE5 Cluster: Ribonucleoside-diphosphate reductase; n...    55   2e-06
UniRef50_Q2LW62 Cluster: Ribonucleoside-diphosphate reductase al...    54   3e-06
UniRef50_Q18BC3 Cluster: Putative ribonucleotide-diphosphate red...    54   4e-06
UniRef50_Q01037 Cluster: Ribonucleoside-diphosphate reductase la...    54   4e-06
UniRef50_A3EPA5 Cluster: Ribonucleoside-diphosphate reductase; n...    53   6e-06
UniRef50_A2PYM5 Cluster: Ribonucleoside-diphosphate reductase al...    53   6e-06
UniRef50_O36411 Cluster: Ribonucleoside-diphosphate reductase; n...    53   8e-06
UniRef50_A3W1N9 Cluster: Ribonucleoside-diphosphate reductase; n...    53   8e-06
UniRef50_A0MN59 Cluster: Ribonucleotide reductase alpha subunit;...    53   8e-06
UniRef50_P50643 Cluster: Ribonucleoside-diphosphate reductase la...    53   8e-06
UniRef50_Q7NEB4 Cluster: Gll3966 protein; n=1; Gloeobacter viola...    52   1e-05
UniRef50_A3I5A9 Cluster: Ribonucleoside-diphosphate reductase; n...    52   1e-05
UniRef50_Q7UI46 Cluster: Vitamin B12-dependent ribonucleotide re...    52   2e-05
UniRef50_A4IY36 Cluster: Ribonucleoside-diphosphate reductase, a...    51   2e-05
UniRef50_Q1FPU1 Cluster: Ribonucleoside-diphosphate reductase; n...    51   3e-05
UniRef50_Q8Y2Y6 Cluster: Ribonucleoside-diphosphate reductase; n...    50   4e-05
UniRef50_A1HDY4 Cluster: Ribonucleoside-diphosphate reductase; n...    50   4e-05
UniRef50_Q3B5C1 Cluster: Ribonucleotide reductase family protein...    50   5e-05
UniRef50_Q3SMN2 Cluster: Ribonucleoside-diphosphate reductase al...    50   7e-05
UniRef50_Q1J1T0 Cluster: Ribonucleoside-diphosphate reductase; n...    50   7e-05
UniRef50_Q120H3 Cluster: Ribonucleotide reductase large subunit;...    50   7e-05
UniRef50_Q0LX20 Cluster: Ribonucleoside-diphosphate reductase; n...    49   9e-05
UniRef50_O55716 Cluster: Ribonucleoside-diphosphate reductase; n...    48   2e-04
UniRef50_Q6MNP6 Cluster: Vitamin B12-dependent ribonucleotide re...    48   2e-04
UniRef50_Q88YQ4 Cluster: Ribonucleoside-diphosphate reductase, a...    48   2e-04
UniRef50_A5JBG3 Cluster: Ribonucleotide reductase, large subunit...    48   2e-04
UniRef50_UPI00004BA6C5 Cluster: UPI00004BA6C5 related cluster; n...    48   3e-04
UniRef50_Q196Z5 Cluster: Ribonucleoside-diphosphate reductase; n...    48   3e-04
UniRef50_A4WLF4 Cluster: Ribonucleoside-diphosphate reductase, a...    48   3e-04
UniRef50_Q9RRW1 Cluster: Ribonucleoside-diphosphate reductase; n...    46   7e-04
UniRef50_Q604J6 Cluster: Ribonucleoside-diphosphate reductase; n...    46   9e-04
UniRef50_Q8ZTP7 Cluster: Ribonucleoside-diphosphate reductase; n...    45   0.002
UniRef50_P78027 Cluster: Ribonucleoside-diphosphate reductase su...    45   0.002
UniRef50_A7CVZ3 Cluster: Ribonucleoside-diphosphate reductase pr...    45   0.002
UniRef50_A1W357 Cluster: Ribonucleoside-diphosphate reductase; n...    45   0.002
UniRef50_A1TJY2 Cluster: Ribonucleoside-diphosphate reductase, a...    44   0.003
UniRef50_P0A5W9 Cluster: Ribonucleoside-diphosphate reductase su...    44   0.003
UniRef50_Q2S5T5 Cluster: Ribonucleoside-diphosphate reductase, a...    44   0.004
UniRef50_P03190 Cluster: Ribonucleoside-diphosphate reductase la...    44   0.004
UniRef50_Q9HPG8 Cluster: Ribonucleoside-diphosphate reductase; n...    42   0.011
UniRef50_Q5DN91 Cluster: Ribonucleotide reductase; n=1; Phage ph...    42   0.014
UniRef50_Q2NME4 Cluster: Ribonucleoside-diphosphate reductase la...    42   0.019
UniRef50_P50620 Cluster: Ribonucleoside-diphosphate reductase su...    42   0.019
UniRef50_O41962 Cluster: Ribonucleoside-diphosphate reductase; n...    41   0.025
UniRef50_A5FCJ4 Cluster: Ribonucleoside-diphosphate reductase, a...    41   0.033
UniRef50_Q5A0N2 Cluster: Putative uncharacterized protein; n=1; ...    41   0.033
UniRef50_O41114 Cluster: A632L protein; n=1; Paramecium bursaria...    40   0.044
UniRef50_Q897Z5 Cluster: Ribonucleoside-diphosphate reductase; n...    40   0.044
UniRef50_A0LDD1 Cluster: Ribonucleoside-diphosphate reductase, a...    40   0.044
UniRef50_P37426 Cluster: Ribonucleoside-diphosphate reductase 1 ...    40   0.044
UniRef50_Q8SCB8 Cluster: Large subunit ribonucleotide reductase;...    40   0.058
UniRef50_Q66LW9 Cluster: Ribonucleoside-diphosphate reductase 1 ...    40   0.058
UniRef50_Q6YRG1 Cluster: Ribonucleoside-diphosphate reductase; n...    39   0.10 
UniRef50_Q1ISM3 Cluster: Ribonucleoside-diphosphate reductase; n...    39   0.10 
UniRef50_Q0W4L0 Cluster: Putative uncharacterized protein; n=2; ...    39   0.13 
UniRef50_O55567 Cluster: P25; n=1; Leucania separata nuclear pol...    38   0.18 
UniRef50_A7HCF4 Cluster: Ribonucleoside-diphosphate reductase, a...    38   0.23 
UniRef50_UPI000155442E Cluster: hypothetical protein ORF046; n=1...    37   0.41 
UniRef50_A3XHF8 Cluster: Ribonucleoside-diphosphate reductase, a...    37   0.54 
UniRef50_Q6LQZ0 Cluster: Putative uncharacterized protein; n=2; ...    36   0.94 
UniRef50_Q7TDH5 Cluster: Ribonucleoside-diphosphate reductase; n...    35   1.6  
UniRef50_Q18GD3 Cluster: Ribonucleoside-diphosphate reductase al...    35   1.6  
UniRef50_O31875 Cluster: Ribonucleoside-diphosphate reductase; n...    35   2.2  
UniRef50_Q5CHN1 Cluster: Putative uncharacterized protein; n=1; ...    34   3.8  
UniRef50_O69981 Cluster: Vitamin B12-dependent ribonucleotide re...    34   3.8  
UniRef50_Q89MB9 Cluster: Vitamin B12-dependent ribonucleotide re...    34   3.8  
UniRef50_Q7RJL4 Cluster: Putative uncharacterized protein PY0324...    33   5.0  
UniRef50_A2FWX8 Cluster: Putative uncharacterized protein; n=1; ...    33   5.0  
UniRef50_Q7REC9 Cluster: Putative uncharacterized protein PY0513...    33   6.6  
UniRef50_A0DYW6 Cluster: Chromosome undetermined scaffold_7, who...    33   6.6  
UniRef50_UPI00006CE942 Cluster: hypothetical repeat containing p...    33   8.8  

>UniRef50_Q4S8W6 Cluster: Ribonucleoside-diphosphate reductase; n=3;
           Tetraodontidae|Rep: Ribonucleoside-diphosphate reductase
           - Tetraodon nigroviridis (Green puffer)
          Length = 898

 Score =  163 bits (396), Expect = 4e-39
 Identities = 83/124 (66%), Positives = 94/124 (75%)
 Frame = +3

Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
           AVCNLASIALNM+V   +TY+F KL  VTKTI +NLNKIID+NYYPVPEAK+SNLRHRPI
Sbjct: 494 AVCNLASIALNMYVTPQRTYDFHKLASVTKTIVKNLNKIIDINYYPVPEAKRSNLRHRPI 553

Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAP 614
           GIGVQGLADAFILMR PYESPEA     +  +     ALEASCELAA+      +   +P
Sbjct: 554 GIGVQGLADAFILMRHPYESPEAQLLNTQIFETIYHAALEASCELAAEFGPYQTY-AGSP 612

Query: 615 ASRG 626
            SRG
Sbjct: 613 VSRG 616



 Score =  147 bits (356), Expect = 3e-34
 Identities = 65/85 (76%), Positives = 72/85 (84%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           PGL DCWG+EFE LY  YEKE R    V+AQ LW AIIE+Q ETGTPYML+KD+CNRKSN
Sbjct: 409 PGLTDCWGEEFEELYTRYEKEGRAKRVVKAQQLWYAIIESQTETGTPYMLYKDACNRKSN 468

Query: 181 QKNLGTIKCSNLCTEIVEYTSDDEV 255
           Q+NLGTI+CSNLCTEIVEYTS DEV
Sbjct: 469 QQNLGTIRCSNLCTEIVEYTSKDEV 493


>UniRef50_P07742 Cluster: Ribonucleoside-diphosphate reductase large
           subunit; n=93; root|Rep: Ribonucleoside-diphosphate
           reductase large subunit - Mus musculus (Mouse)
          Length = 792

 Score =  153 bits (370), Expect = 5e-36
 Identities = 76/107 (71%), Positives = 86/107 (80%), Gaps = 1/107 (0%)
 Frame = +3

Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
           AVCNLAS+ALNM+V    TY+F+KL EVTK I  NLNKIID+NYYP+PEA  SN RHRPI
Sbjct: 442 AVCNLASLALNMYVTPEHTYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPI 501

Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYL-KLFTMGALEASCELA 572
           GIGVQGLADAFILMR P+ESPEA   +NK + +    GALEASCELA
Sbjct: 502 GIGVQGLADAFILMRYPFESPEA-QLLNKQIFETIYYGALEASCELA 547



 Score =  145 bits (351), Expect = 1e-33
 Identities = 65/85 (76%), Positives = 73/85 (85%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           PGL + WG+EFE LYE+YEK+ R    V+AQ LW AIIE+Q ETGTPYML+KDSCNRKSN
Sbjct: 357 PGLDEVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSN 416

Query: 181 QKNLGTIKCSNLCTEIVEYTSDDEV 255
           Q+NLGTIKCSNLCTEIVEYTS DEV
Sbjct: 417 QQNLGTIKCSNLCTEIVEYTSKDEV 441



 Score = 39.9 bits (89), Expect = 0.058
 Identities = 18/35 (51%), Positives = 23/35 (65%)
 Frame = +2

Query: 509 LNQQIFETIYYGSTRGKL*TSSKSMGVYDTYDGCP 613
           LN+QIFETIYYG+        +K  G Y+TY+G P
Sbjct: 527 LNKQIFETIYYGALEASC-ELAKEYGPYETYEGSP 560


>UniRef50_P23921 Cluster: Ribonucleoside-diphosphate reductase large
           subunit; n=110; root|Rep: Ribonucleoside-diphosphate
           reductase large subunit - Homo sapiens (Human)
          Length = 792

 Score =  149 bits (362), Expect = 5e-35
 Identities = 75/107 (70%), Positives = 85/107 (79%), Gaps = 1/107 (0%)
 Frame = +3

Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
           AVCNLAS+ALNM+V    TY+FKKL EVTK +  NLNKIID+NYYPVPEA  SN RHRPI
Sbjct: 442 AVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPI 501

Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYL-KLFTMGALEASCELA 572
           GIGVQGLADAFILMR P+ES EA   +NK + +    GALEASC+LA
Sbjct: 502 GIGVQGLADAFILMRYPFESAEA-QLLNKQIFETIYYGALEASCDLA 547



 Score =  142 bits (345), Expect = 6e-33
 Identities = 64/85 (75%), Positives = 72/85 (84%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           PGL + WG+EFE LY +YEK+ R    V+AQ LW AIIE+Q ETGTPYML+KDSCNRKSN
Sbjct: 357 PGLDEVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSN 416

Query: 181 QKNLGTIKCSNLCTEIVEYTSDDEV 255
           Q+NLGTIKCSNLCTEIVEYTS DEV
Sbjct: 417 QQNLGTIKCSNLCTEIVEYTSKDEV 441



 Score = 41.9 bits (94), Expect = 0.014
 Identities = 25/76 (32%), Positives = 36/76 (47%)
 Frame = +2

Query: 464 FYFNAFTLRKSRSY*LNQQIFETIYYGSTRGKL*TSSKSMGVYDTYDGCPCKSRAYYSTT 643
           F    +    + +  LN+QIFETIYYG+        +K  G Y+TY+G P  S+      
Sbjct: 512 FILMRYPFESAEAQLLNKQIFETIYYGALEASC-DLAKEQGPYETYEGSPV-SKGILQYD 569

Query: 644 CGIKNPTRFYGDWDLL 691
                PT  + DW +L
Sbjct: 570 MWNVTPTDLW-DWKVL 584


>UniRef50_Q01H73 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Ostreococcus tauri|Rep: Ribonucleoside-diphosphate
           reductase - Ostreococcus tauri
          Length = 840

 Score =  141 bits (342), Expect = 1e-32
 Identities = 62/84 (73%), Positives = 72/84 (85%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           PGL+DCWG+EFE+LYE YE E +    ++AQ LW AI+E+QVETG PYMLFKD+CNRKSN
Sbjct: 363 PGLSDCWGEEFETLYEKYEAEGKGKKTIKAQQLWFAILESQVETGNPYMLFKDACNRKSN 422

Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252
           Q+NLGTIK SNLCTEIVEYTS DE
Sbjct: 423 QQNLGTIKSSNLCTEIVEYTSPDE 446



 Score =  103 bits (246), Expect = 5e-21
 Identities = 56/106 (52%), Positives = 70/106 (66%), Gaps = 22/106 (20%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDN----------------------KTYNFKKLKEVTKTITENLN 365
           +AVCNLASIAL  FV +N                      + ++  KL E+T+ +T NLN
Sbjct: 447 TAVCNLASIALPRFVIENNPSSPTGRTETKKLVGSLKSKERFFDHSKLFEITRKVTRNLN 506

Query: 366 KIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEA 503
           +IIDVNYYPV  AK SN+RHRPIG+GVQGLAD FIL+ LP++SPEA
Sbjct: 507 RIIDVNYYPVEAAKNSNMRHRPIGLGVQGLADVFILLGLPFDSPEA 552


>UniRef50_Q9SJ20 Cluster: Ribonucleoside-diphosphate reductase large
           subunit; n=17; cellular organisms|Rep:
           Ribonucleoside-diphosphate reductase large subunit -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 816

 Score =  136 bits (330), Expect = 4e-31
 Identities = 61/84 (72%), Positives = 69/84 (82%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           PGLADCWG EFE+LY  YE+E +    V+AQ LW  I+ +QVETGTPYMLFKDSCNRKSN
Sbjct: 357 PGLADCWGAEFETLYTKYEREGKAKKVVQAQQLWYEILTSQVETGTPYMLFKDSCNRKSN 416

Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252
           Q+NLGTIK SNLCTEI+EYTS  E
Sbjct: 417 QQNLGTIKSSNLCTEIIEYTSPTE 440



 Score =  121 bits (292), Expect = 1e-26
 Identities = 72/144 (50%), Positives = 91/144 (63%), Gaps = 19/144 (13%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDD-------------------NKTYNFKKLKEVTKTITENLNKII 374
           +AVCNLASIAL  FV +                   N+ ++F+KL EVT T+T NLNKII
Sbjct: 441 TAVCNLASIALPRFVREKGVPLDSHPPKLAGSLDSKNRYFDFEKLAEVTATVTVNLNKII 500

Query: 375 DVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALE 554
           DVNYYPV  AK SN+RHRPIGIGVQGLADAFIL+ +P++SPEA        +     AL+
Sbjct: 501 DVNYYPVETAKTSNMRHRPIGIGVQGLADAFILLGMPFDSPEAQQLNKDIFETIYYHALK 560

Query: 555 ASCELAAKVWECMIHTTDAPASRG 626
           AS ELAA++     +   +P S+G
Sbjct: 561 ASTELAARLGPYETY-AGSPVSKG 583


>UniRef50_Q8JKL8 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Heliothis zea virus 1|Rep: Ribonucleoside-diphosphate
           reductase - Heliothis zea virus 1
          Length = 939

 Score =  133 bits (321), Expect = 4e-30
 Identities = 58/84 (69%), Positives = 71/84 (84%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           PGL+DCWG+EFE+ Y  YE+E R+V +V A+ LWKAI+ AQVETGTPY+L+KD+ NR SN
Sbjct: 359 PGLSDCWGEEFEAKYTAYEQEGRYVRRVDARELWKAIVTAQVETGTPYILYKDTVNRNSN 418

Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252
           Q++LGTIK SNLCTEIVEY S DE
Sbjct: 419 QRHLGTIKGSNLCTEIVEYASPDE 442



 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 55/127 (43%), Positives = 72/127 (56%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           +AVC LAS+ L  FV+  K +N   L +  + +T NLNKIID   YP+P A KSN +HRP
Sbjct: 443 TAVCVLASVNLPKFVE-GKVFNLNLLAKTVRLVTRNLNKIIDNALYPIPSAAKSNFKHRP 501

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDA 611
           IGIGVQG ADA  +M + YE    +N      +     AL  SC+L A+V         +
Sbjct: 502 IGIGVQGYADALAMMGIAYEDSMQLN--RDIFETIYHAALTESCQL-ARVHGVYESYHGS 558

Query: 612 PASRGHI 632
           P SRG +
Sbjct: 559 PTSRGEL 565


>UniRef50_O12935 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Nucleopolyhedrovirus|Rep: Ribonucleoside-diphosphate
           reductase - Spodoptera exigua MNPV
          Length = 770

 Score =  128 bits (308), Expect = 2e-28
 Identities = 67/126 (53%), Positives = 88/126 (69%), Gaps = 1/126 (0%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           +AVCNLASIA+N  VD D KT+++  LK +TK I  NLNKIIDVN+YP  E+++SN +HR
Sbjct: 425 TAVCNLASIAVNKCVDVDAKTFDYVLLKHLTKIIVRNLNKIIDVNHYPTAESERSNKKHR 484

Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTD 608
           PIG+G+QGLADAF+L+ + Y+S +A        +     ALEASCEL AK+       TD
Sbjct: 485 PIGVGIQGLADAFVLLDIAYDSDDARFVNYSIAETIYFAALEASCEL-AKINGPYESYTD 543

Query: 609 APASRG 626
           +P SRG
Sbjct: 544 SPVSRG 549



 Score =  104 bits (249), Expect = 2e-21
 Identities = 48/84 (57%), Positives = 60/84 (71%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           P LAD +G +FE  Y  YE    +  QV+A+ L++ I+E  VETG PYML+KD CN  SN
Sbjct: 341 PDLADKYGFDFEMRYCDYENAQVYERQVKARDLFRFIVETNVETGGPYMLYKDHCNNFSN 400

Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252
           QKNLGTIKCSNLC EIV+Y  ++E
Sbjct: 401 QKNLGTIKCSNLCAEIVQYCDENE 424


>UniRef50_Q75BW6 Cluster: Ribonucleoside-diphosphate reductase; n=4;
           Saccharomycetaceae|Rep: Ribonucleoside-diphosphate
           reductase - Ashbya gossypii (Yeast) (Eremothecium
           gossypii)
          Length = 864

 Score =  118 bits (283), Expect = 2e-25
 Identities = 53/84 (63%), Positives = 66/84 (78%)
 Frame = +1

Query: 4   GLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQ 183
           GL+DC+G+ FE LY  YE+E     +V+AQ LW+ I+ +Q ETG P+ML+KD+CN KSNQ
Sbjct: 379 GLSDCYGEAFEQLYVRYERELEPYRRVKAQELWREILLSQTETGGPFMLYKDACNSKSNQ 438

Query: 184 KNLGTIKCSNLCTEIVEYTSDDEV 255
           KNLGTIK SNLC EIVEY+S DEV
Sbjct: 439 KNLGTIKSSNLCCEIVEYSSRDEV 462



 Score =  111 bits (267), Expect = 2e-23
 Identities = 58/129 (44%), Positives = 81/129 (62%), Gaps = 3/129 (2%)
 Frame = +3

Query: 255 AVCNLASIALNMFVD---DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRH 425
           AVCNLAS+AL  FV    D  T+++ +L  V K +T NL+K ID+  YPVPEA++SN +H
Sbjct: 463 AVCNLASVALPTFVSVTSDAITFDYARLHSVVKVMTRNLDKAIDIGDYPVPEAERSNKKH 522

Query: 426 RPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTT 605
           RP+ +GVQGLAD F+LMR P+   EA     +  +     A+E S ELAA+ +       
Sbjct: 523 RPLALGVQGLADVFMLMRFPFNGEEAAQMNREIFETIYHAAVETSIELAAE-YGVYASFV 581

Query: 606 DAPASRGHI 632
            +PAS+G +
Sbjct: 582 GSPASKGEL 590


>UniRef50_Q9QAL9 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Shrimp white spot syndrome virus|Rep:
           Ribonucleoside-diphosphate reductase - White spot
           syndrome virus (WSSV)
          Length = 848

 Score =  109 bits (263), Expect = 5e-23
 Identities = 58/131 (44%), Positives = 86/131 (65%), Gaps = 6/131 (4%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDN-----KTY-NFKKLKEVTKTITENLNKIIDVNYYPVPEAKKS 413
           +AVCNLASIA+N FV  +     + Y +++++K V K +T NL+K+IDVN+Y V + + S
Sbjct: 464 TAVCNLASIAVNKFVKYSPIPSLRPYVDYREMKRVVKIMTRNLDKVIDVNFYAVDKTRIS 523

Query: 414 NLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECM 593
           N++ RP+G+GVQGLAD F  +R+P+ES EA     +  +    GALEASCE+A +  E  
Sbjct: 524 NMKTRPMGLGVQGLADLFFKLRIPFESEEAALINKRIFETIYYGALEASCEIAKEKGETY 583

Query: 594 IHTTDAPASRG 626
                +P S+G
Sbjct: 584 ELFEGSPLSKG 594



 Score =  105 bits (251), Expect = 1e-21
 Identities = 47/84 (55%), Positives = 64/84 (76%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           PGL+D  G+EF++LYE YE E +    V+A+ L+  I  A++ETGTPY+ FKD+ NRKSN
Sbjct: 380 PGLSDVHGEEFKALYEKYEAEGKGKEVVKARALFDQINSARIETGTPYVCFKDTINRKSN 439

Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252
           Q+N+G IK SNLCTEIV+Y+  +E
Sbjct: 440 QENVGIIKSSNLCTEIVQYSDSEE 463


>UniRef50_Q7T6Y8 Cluster: Ribonucleoside-diphosphate reductase large
           chain; n=1; Acanthamoeba polyphaga mimivirus|Rep:
           Ribonucleoside-diphosphate reductase large chain -
           Mimivirus
          Length = 881

 Score =  100 bits (240), Expect = 3e-20
 Identities = 50/109 (45%), Positives = 74/109 (67%), Gaps = 3/109 (2%)
 Frame = +3

Query: 255 AVCNLASIALNMFV---DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRH 425
           +VCNL+SI L  FV   D+  T+N++KL ++++ +T NLN IID+N+YP+ + + +NLR 
Sbjct: 508 SVCNLSSICLPRFVKIIDEVPTFNYQKLFKISRILTRNLNNIIDINFYPLDKTRITNLRD 567

Query: 426 RPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           RPIGIGVQGLAD F + + P++S  A +   K  +    GAL  S +LA
Sbjct: 568 RPIGIGVQGLADVFAMFKTPFDSEIARDLNRKIFETIYYGALTESNKLA 616



 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 40/78 (51%), Positives = 53/78 (67%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           P L + +G EF   Y  YE E  ++ Q+RA  LW  I+E+Q+ETG PY++FKD+ N KSN
Sbjct: 423 PNLLNKYGDEFTKEYLKYESEGIYLKQIRAIDLWFKIMESQIETGVPYVMFKDAINDKSN 482

Query: 181 QKNLGTIKCSNLCTEIVE 234
           Q N+G +  SNLC EIVE
Sbjct: 483 QINIGVVNGSNLCCEIVE 500


>UniRef50_Q6MLM3 Cluster: Ribonucleoside-diphosphate reductase alpha
           chain; n=14; Bacteria|Rep: Ribonucleoside-diphosphate
           reductase alpha chain - Bdellovibrio bacteriovorus
          Length = 801

 Score = 95.9 bits (228), Expect = 8e-19
 Identities = 46/109 (42%), Positives = 70/109 (64%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           +AVCNL S+ L   V+ N  +NF+KL    +T  + L++++D+N+YP+P A+ SN + RP
Sbjct: 444 TAVCNLGSVNLARHVE-NGQFNFEKLARSVRTAVKYLDRVVDINFYPIPTAQDSNHKWRP 502

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
           +G+GV GL DA  LM+LP++S  A +   K  +     AL  SCEL+ K
Sbjct: 503 VGLGVMGLQDALFLMKLPFDSAAARDLSAKVQEEIYYNALVTSCELSEK 551



 Score = 69.3 bits (162), Expect = 8e-11
 Identities = 34/86 (39%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           P   D +G+EFE  Y   E++  ++ Q++A+ L+  +++   +TG  +M FKD  N K+N
Sbjct: 358 PHFVDTYGEEFEKAYVEAEEKKLYIKQLKARDLYSRMMKTLAQTGNGWMTFKDHANLKAN 417

Query: 181 QKNL--GTIKCSNLCTEIVEYTSDDE 252
           Q       I  SNLCTEI+E TSD E
Sbjct: 418 QTGEAGNVIHLSNLCTEILEVTSDKE 443


>UniRef50_P26685 Cluster: Ribonucleoside-diphosphate reductase large
           chain; n=2; African swine fever virus|Rep:
           Ribonucleoside-diphosphate reductase large chain -
           African swine fever virus (isolate Malawi Lil 20/1)
           (ASFV)
          Length = 779

 Score = 93.5 bits (222), Expect = 4e-18
 Identities = 47/105 (44%), Positives = 66/105 (62%)
 Frame = +3

Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437
           VCNLA++ L  F+ ++ +Y+++ L E    +TENL+ IID  YYP    ++SN+RHRPIG
Sbjct: 439 VCNLAAVNLAAFIRES-SYDYRGLIEAAGNVTENLDNIIDNGYYPTEATRRSNMRHRPIG 497

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           IGV GLAD F  +++ + SPEAI            GA+  S ELA
Sbjct: 498 IGVFGLADVFASLKMKFGSPEAIAIDEAIHAALYYGAMRRSIELA 542



 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 30/68 (44%), Positives = 41/68 (60%)
 Frame = +1

Query: 25  KEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIK 204
           +EF+ LY  Y  E R+     A+ + K   +  V+ G PY+ FKD+ NRKSN  ++GTI 
Sbjct: 358 REFKKLYYQYVAEKRYTGVTTAKEIIKEWFKTVVQVGNPYIGFKDAINRKSNLSHVGTIT 417

Query: 205 CSNLCTEI 228
            SNLC EI
Sbjct: 418 NSNLCIEI 425


>UniRef50_O41111 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Chlorovirus|Rep: Ribonucleoside-diphosphate reductase -
           Paramecium bursaria Chlorella virus 1 (PBCV-1)
          Length = 771

 Score = 93.1 bits (221), Expect = 6e-18
 Identities = 46/107 (42%), Positives = 71/107 (66%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           +AVC + S+ L  +V ++K ++F  L++  K + +NL++ IDV  YP+ EA+ SN R RP
Sbjct: 453 TAVCVIGSVVLKNYVKNDK-FDFDDLRKNVKILAKNLDRSIDVMSYPIKEAETSNKRRRP 511

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           IG+GVQGL D F  ++LP++SPEA +   +  +     A+EAS ELA
Sbjct: 512 IGVGVQGLQDVFFKLKLPFDSPEARDLNREIFEHIYYAAVEASVELA 558



 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 39/84 (46%), Positives = 55/84 (65%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           PGL D +G E+  LY  YE E +    V+A+ +W  ++   +ETG PY+  KD+ N+K+ 
Sbjct: 369 PGLTDAFGDEYAELYTRYEAEGKAKNVVKARDVWNTMVTTIIETGQPYVANKDTVNKKNM 428

Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252
           Q N GTI+ SNLC EI+EYTS +E
Sbjct: 429 QSNAGTIRGSNLCIEILEYTSKEE 452


>UniRef50_A7IY07 Cluster: Putative uncharacterized protein B832R; n=1;
            Paramecium bursaria Chlorella virus NY2A|Rep: Putative
            uncharacterized protein B832R - Paramecium bursaria
            Chlorella virus NY2A (PBCV-NY2A)
          Length = 1103

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 45/107 (42%), Positives = 68/107 (63%)
 Frame = +3

Query: 252  SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
            +AVC + S+ L  +V ++K ++F  L++  K + +NL++ IDV  YP+ EA+ SN   RP
Sbjct: 785  TAVCVIGSVVLKNYVKNDK-FDFDDLRKNVKILAKNLDRSIDVMAYPIKEAETSNKLRRP 843

Query: 432  IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            IG+GVQGL D F  +R  Y+SPEA +   +  +     A+EAS ELA
Sbjct: 844  IGVGVQGLQDVFFKLRFSYDSPEARDLNREIFEHIYYAAVEASVELA 890



 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 33/73 (45%), Positives = 47/73 (64%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           PGL D +G E+  LYE YE E +    V+A+ +W  ++   +ETG PY+  KD+ N+K+ 
Sbjct: 365 PGLTDAFGDEYAELYERYEAEGKAKNVVKARDVWNTMVTTIIETGQPYVSNKDAVNKKNM 424

Query: 181 QKNLGTIKCSNLC 219
           Q N GTI+ SNLC
Sbjct: 425 QMNAGTIRGSNLC 437


>UniRef50_Q4J4L6 Cluster: Ribonucleoside-diphosphate reductase; n=3;
            cellular organisms|Rep: Ribonucleoside-diphosphate
            reductase - Azotobacter vinelandii AvOP
          Length = 1338

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 42/106 (39%), Positives = 64/106 (60%)
 Frame = +3

Query: 255  AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
            AVCNL SI L   ++D +  + +KL    KT    L+ +ID+NYY V  A+ +N RHRP+
Sbjct: 978  AVCNLGSINLVNHINDGRL-DTEKLSRTVKTAVRMLDNVIDINYYSVDTARNANFRHRPV 1036

Query: 435  GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            G+G+ G  DA  L  + Y S  AI   ++ ++  +  A++ASC+LA
Sbjct: 1037 GLGIMGFQDALYLQHIAYGSEAAIAFADRSMEAISYYAIQASCDLA 1082



 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 35/88 (39%), Positives = 51/88 (57%), Gaps = 5/88 (5%)
 Frame = +1

Query: 7    LADCWGKEFESLYETYEKENRF-----VXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNR 171
            L D  G+ FE  YE YE   ++        + A+ LW+ ++    ETG P++ FKD CN 
Sbjct: 890  LHDLTGRAFEERYEYYEALTQYGKIKLFKTIAAKDLWRKMLSMLFETGHPWLTFKDPCNL 949

Query: 172  KSNQKNLGTIKCSNLCTEIVEYTSDDEV 255
            +S Q+++G +  SNLCTEI   TSD E+
Sbjct: 950  RSPQQHVGVVHSSNLCTEITLNTSDSEI 977


>UniRef50_Q9HMU3 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Halobacterium salinarum|Rep: Ribonucleoside-diphosphate
           reductase - Halobacterium salinarium (Halobacterium
           halobium)
          Length = 804

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 41/109 (37%), Positives = 67/109 (61%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           +AVCNL S+ L   +DD    + ++L E  +T    L+ ++D+N+YP   A++SN+RHRP
Sbjct: 447 TAVCNLGSVNLARHLDDGDI-DREQLSETVETAMRMLDNVVDLNFYPTENAERSNMRHRP 505

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
           +G+GV G  DA   MR+P  S +A++  +   +     A+ AS +LAA+
Sbjct: 506 VGLGVMGFHDALQQMRVPMASDDALDRADALQEYVAYHAIGASADLAAE 554



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 35/88 (39%), Positives = 50/88 (56%), Gaps = 6/88 (6%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKE------NRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCN 168
           L + +G +F   Y  YE         RF  +V A  LW+ ++    ETG P++ FKD CN
Sbjct: 360 LYELYGSDFAERYREYEAMADDGDIQRF-ERVDATDLWRTMLTRLFETGHPWLTFKDPCN 418

Query: 169 RKSNQKNLGTIKCSNLCTEIVEYTSDDE 252
            +S Q + GT++ SNLCTEI   TS++E
Sbjct: 419 VRSPQDHAGTVRSSNLCTEITLNTSEEE 446


>UniRef50_Q3AEA3 Cluster: Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent, intein-containing; n=2;
           Bacteria|Rep: Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent, intein-containing -
           Carboxydothermus hydrogenoformans (strain Z-2901 / DSM
           6008)
          Length = 1101

 Score = 83.8 bits (198), Expect = 4e-15
 Identities = 42/104 (40%), Positives = 63/104 (60%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL SI L   V D +  +++ L++  K     L+ +IDVN+YP+PE +K   + R IG+
Sbjct: 627 CNLGSINLANMVKDGEI-DWEHLEKTVKLAVRFLDNVIDVNHYPLPEIEKMTKKTRKIGL 685

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           GV G AD  I + +PY+S EA+N  +K ++     + EAS ELA
Sbjct: 686 GVMGFADMLIKLNIPYDSEEALNLADKVMEFINKKSKEASAELA 729


>UniRef50_O84834 Cluster: Ribonucleoside-diphosphate reductase
           subunit alpha; n=29; Bacteria|Rep:
           Ribonucleoside-diphosphate reductase subunit alpha -
           Chlamydia trachomatis
          Length = 1047

 Score = 83.4 bits (197), Expect = 5e-15
 Identities = 41/89 (46%), Positives = 56/89 (62%), Gaps = 5/89 (5%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEK-----ENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSC 165
           PGL D +G+EFE LYE YE+     E R   +V A+ LW+ ++    ETG P+M FKD  
Sbjct: 595 PGLHDAYGEEFERLYEEYERKVDTGEIRLFKKVEAEDLWRKMLSMLFETGHPWMTFKDPS 654

Query: 166 NRKSNQKNLGTIKCSNLCTEIVEYTSDDE 252
           N +S Q + G ++CSNLCTEI+   S+ E
Sbjct: 655 NIRSAQDHKGVVRCSNLCTEILLNCSETE 683



 Score = 77.4 bits (182), Expect = 3e-13
 Identities = 41/107 (38%), Positives = 61/107 (57%)
 Frame = +3

Query: 252  SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
            +AVCNL SI L   +  +   + +KL E        L+ +ID+N+YP  EAK++N  HR 
Sbjct: 684  TAVCNLGSINLVQHIVGDGL-DEEKLSETISIAVRMLDNVIDINFYPTKEAKEANFAHRA 742

Query: 432  IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            IG+GV G  DA   + + Y S EA+   +   +L +  A++ASC LA
Sbjct: 743  IGLGVMGFQDALYKLDISYASQEAVEFADYSSELISYYAIQASCLLA 789


>UniRef50_Q67KQ2 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Symbiobacterium thermophilum|Rep:
           Ribonucleoside-diphosphate reductase - Symbiobacterium
           thermophilum
          Length = 776

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 43/108 (39%), Positives = 61/108 (56%), Gaps = 4/108 (3%)
 Frame = +3

Query: 261 CNLASIALNMFVD----DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           CNL SI L  FV     D    ++++L EV +T T  L+ +ID N YP+P+  +  LR R
Sbjct: 282 CNLGSINLANFVKNPYTDRAEVDWERLGEVARTATRFLDNVIDANKYPLPQIAEKALRDR 341

Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            IG+G+ G A+  + M LPY+S EA+   N+ +      ALE S  LA
Sbjct: 342 RIGLGIMGWAEMLVQMGLPYDSEEAVALGNRVMTFIKQKALEESMALA 389



 Score = 36.3 bits (80), Expect = 0.71
 Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
 Frame = +1

Query: 43  YETYEKENRFVX-QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219
           YE     N  V  ++ A+++W  ++E   +TG P ++F D  NR++   ++  I+ +N C
Sbjct: 212 YELINPRNGEVTGKLSAKLVWDKLVENAWKTGEPGIVFIDRINRRNPNNHVEVIEATNPC 271

Query: 220 TE 225
            E
Sbjct: 272 GE 273


>UniRef50_A2XAQ8 Cluster: Ribonucleoside-diphosphate reductase; n=4;
           Oryza sativa|Rep: Ribonucleoside-diphosphate reductase -
           Oryza sativa subsp. indica (Rice)
          Length = 676

 Score = 78.2 bits (184), Expect = 2e-13
 Identities = 32/52 (61%), Positives = 41/52 (78%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFK 156
           PGLADCWG EF++LY+ YE+E +    V AQ LW  I++AQ+ETGTPYML+K
Sbjct: 357 PGLADCWGDEFQNLYKKYEREGKAKKVVSAQALWFDILKAQIETGTPYMLYK 408



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 16/35 (45%), Positives = 22/35 (62%)
 Frame = +2

Query: 509 LNQQIFETIYYGSTRGKL*TSSKSMGVYDTYDGCP 613
           LN+ IFETIYY + +     ++K  G Y+TY G P
Sbjct: 412 LNKDIFETIYYHALKASAEIAAKE-GPYETYSGSP 445


>UniRef50_Q39JT6 Cluster: Ribonucleoside-diphosphate reductase;
           n=86; Bacteria|Rep: Ribonucleoside-diphosphate reductase
           - Burkholderia sp. (strain 383) (Burkholderia cepacia
           (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 998

 Score = 77.8 bits (183), Expect = 2e-13
 Identities = 41/110 (37%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
 Frame = +3

Query: 255 AVCNLASIALNMFV----DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422
           AVCNL S+ L   +    D +   +  KLK         L+ +ID+NYY V +A+ SNL+
Sbjct: 603 AVCNLGSVNLVAHLVKQADGSFALDHDKLKRTISVAMRMLDNVIDINYYAVAKARNSNLK 662

Query: 423 HRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           HRP+G+G+ G  D   L+R PY S  A+   ++ ++     A  AS ELA
Sbjct: 663 HRPVGMGIMGFQDCLHLLRTPYASEAAVAFADRSMEAVCYYAYHASTELA 712



 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 37/90 (41%), Positives = 53/90 (58%), Gaps = 5/90 (5%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEK-----ENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSC 165
           P L D +G EFE+ Y  YE      E +   ++ A  LW+ ++    ETG P++ FKD C
Sbjct: 513 PDLHDKFGAEFEAAYTAYEDKVARGEIKLFKKIPAAQLWRKMLGMLFETGHPWITFKDPC 572

Query: 166 NRKSNQKNLGTIKCSNLCTEIVEYTSDDEV 255
           N +S Q+++G +  SNLCTEI   TSD E+
Sbjct: 573 NVRSPQQHVGVVHSSNLCTEITLNTSDSEI 602


>UniRef50_Q3E5I1 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Chloroflexus|Rep: Ribonucleoside-diphosphate reductase -
           Chloroflexus aurantiacus J-10-fl
          Length = 822

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 44/127 (34%), Positives = 69/127 (54%), Gaps = 5/127 (3%)
 Frame = +3

Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437
           VCNL SI L  FV D  T +++ L++V    T  L+ +ID N+YP+ +  + + R R IG
Sbjct: 312 VCNLGSINLGKFVTDAGTIDWESLRDVVHESTRFLDNVIDANHYPLEQITQLSQRIRRIG 371

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK-----VWECMIHT 602
           +GV G AD  + + +PY S +AI+   + ++     +  AS +LA +      WE  I  
Sbjct: 372 LGVMGWADMLVRLGIPYNSAQAIDLARQVMRFIDEESKVASEQLARERGPFPEWEYSIWG 431

Query: 603 TDAPASR 623
            DA  +R
Sbjct: 432 PDATCAR 438


>UniRef50_P74911 Cluster: Ribonucleoside-diphosphate reductase; n=5;
           Thermoplasmatales|Rep: Ribonucleoside-diphosphate
           reductase - Thermoplasma acidophilum
          Length = 857

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 41/104 (39%), Positives = 57/104 (54%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL SI L+ +V D K  +F +L+E   T T  L+ +ID N +PV + KK     R IG+
Sbjct: 445 CNLGSINLSKYVVDGKKIDFDRLRETVWTATRFLDDVIDANKFPVEQIKKVTRMTRKIGL 504

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           GV G AD  I + +PY S EA+    K +      + +AS  LA
Sbjct: 505 GVMGFADMLIKLEIPYNSWEALEIGEKVMSFINDESHKASQALA 548



 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 19/56 (33%), Positives = 35/56 (62%)
 Frame = +1

Query: 58  KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           +  + + +++A+ +W AII+   +T  P ++F D  NRK+  KN+G I+ +N C E
Sbjct: 381 RTKKIMKRIKAREIWDAIIDQAWKTADPGLIFLDEINRKNPVKNVGDIESTNPCGE 436


>UniRef50_UPI0000F5175D Cluster: hypothetical protein Faci_03000650;
            n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
            protein Faci_03000650 - Ferroplasma acidarmanus fer1
          Length = 1136

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 38/106 (35%), Positives = 58/106 (54%)
 Frame = +3

Query: 261  CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
            CNL SI L  FV+D K +N+++ +E     T  L  ++D N +PV   K    + R IG+
Sbjct: 815  CNLGSINLAKFVEDGK-FNYERYRETIDVATRFLENVVDANKFPVESIKNMTRKTRKIGL 873

Query: 441  GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
            G+ G ADA I++ +PY S EA+      +K     +   S +LAA+
Sbjct: 874  GIMGFADALIMLGIPYNSNEALEFAENVMKTLNDESHMESQKLAAE 919



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 19/54 (35%), Positives = 32/54 (59%)
 Frame = +1

Query: 58  KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219
           ++ +   +V+A  LW +II+    T  P M+F D  N+K+  KN+G I+ +N C
Sbjct: 385 RDGKVTGRVKATTLWNSIIDHAWLTADPGMIFLDEINKKNPVKNIGYIESTNPC 438


>UniRef50_Q8R7R2 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Thermoanaerobacter tengcongensis|Rep:
           Ribonucleoside-diphosphate reductase -
           Thermoanaerobacter tengcongensis
          Length = 691

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 40/105 (38%), Positives = 62/105 (59%)
 Frame = +3

Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437
           VCNL +I L  FV++ K  NF++L+E  K     L+ ++D+  Y +P+ K+   + R +G
Sbjct: 272 VCNLGAINLVAFVENGKI-NFEELEETVKIAVRFLDNVLDLGAYVLPQNKEMAQKLRRVG 330

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           +G+ GLADA ILM L Y S E++    + ++     A  AS ELA
Sbjct: 331 LGLMGLADALILMNLRYGSEESLKATEEIVRRIRDAAYRASVELA 375


>UniRef50_Q6A5Y5 Cluster: Ribonucleoside-diphosphate reductase alpha
           chain; n=6; Actinobacteria (class)|Rep:
           Ribonucleoside-diphosphate reductase alpha chain -
           Propionibacterium acnes
          Length = 856

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 36/112 (32%), Positives = 68/112 (60%), Gaps = 3/112 (2%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDD---NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422
           +AVCNLAS+ L   +      +  ++ +L   T+    +L+ ++D+    VP+A++SN  
Sbjct: 465 TAVCNLASVNLAAHLAGPRGKRRLDWDQLAATTRLAVRHLDNLVDITASAVPQAQRSNEE 524

Query: 423 HRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
           +R IG+GV GL D    +R+PY+SP+A   +++ ++  +  A++ S +LAA+
Sbjct: 525 NRAIGLGVMGLTDMLEQIRVPYDSPDACEIVDRVVEFISWHAIDTSADLAAE 576



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 6/82 (7%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKE------NRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDS 162
           P L +  G +F   Y  Y ++       RF  +  A+  ++AI+ +   T  P++ +KDS
Sbjct: 376 PDLTELTGSDFSKRYAQYVEQAEAGKIKRF-RRTTAREQFRAILVSLQTTSHPWLTWKDS 434

Query: 163 CNRKSNQKNLGTIKCSNLCTEI 228
            N ++   N GTI  SNLCTEI
Sbjct: 435 INTRALNSNTGTIHSSNLCTEI 456


>UniRef50_A4L245 Cluster: Ribonucleotide reductase large subunit;
           n=1; Gryllus bimaculatus nudivirus|Rep: Ribonucleotide
           reductase large subunit - Gryllus bimaculatus nudivirus
          Length = 683

 Score = 73.7 bits (173), Expect = 4e-12
 Identities = 32/77 (41%), Positives = 52/77 (67%)
 Frame = +1

Query: 25  KEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIK 204
           KEFE LYET+  E ++     ++ ++K II+  + TG+PY++F D+ N+ +N K+LG IK
Sbjct: 294 KEFEELYETFVSEQKYTNMYESRKIFKDIIKNILMTGSPYIIFIDNVNKFNNIKHLGKIK 353

Query: 205 CSNLCTEIVEYTSDDEV 255
             NLC+EI  Y ++D +
Sbjct: 354 TLNLCSEITNYCNEDVI 370


>UniRef50_Q8TQ86 Cluster: Ribonucleoside-diphosphate reductase; n=4;
           Methanomicrobia|Rep: Ribonucleoside-diphosphate
           reductase - Methanosarcina acetivorans
          Length = 558

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 39/106 (36%), Positives = 59/106 (55%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL S+ L++FV D K  N+  L+E        L+  ID+N YPVPE  ++  + R IG+
Sbjct: 270 CNLGSLNLSLFVADGKI-NWDFLRETAGKAVRFLDNEIDINVYPVPEIAEATRKTRKIGL 328

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
           GV G  D  + + L Y+S EA+    K ++     A+  S +LAA+
Sbjct: 329 GVMGFHDMLLKLGLSYDSTEAVELAEKLMEQINWAAVRESRKLAAE 374


>UniRef50_Q6R7H4 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Ostreid herpesvirus 1|Rep: Ribonucleoside-diphosphate
           reductase - Ostreid herpesvirus 1
          Length = 835

 Score = 72.5 bits (170), Expect = 9e-12
 Identities = 36/85 (42%), Positives = 51/85 (60%), Gaps = 1/85 (1%)
 Frame = +1

Query: 4   GLADCWGKEFESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           GL + +G++F   Y  +E   +     V A+ L+  I      TG PY+LFKD+ N +SN
Sbjct: 377 GLEELYGEKFVRAYRAHEANPKIKRTTVSARKLFSDIANMMWSTGEPYILFKDAVNERSN 436

Query: 181 QKNLGTIKCSNLCTEIVEYTSDDEV 255
            K+LGTIK SNLC EIV+Y   +E+
Sbjct: 437 HKHLGTIKNSNLCCEIVQYCDTNEI 461



 Score = 46.8 bits (106), Expect(2) = 6e-07
 Identities = 22/54 (40%), Positives = 33/54 (61%)
 Frame = +3

Query: 411 SNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           SNL+HRP GIG+QGL D F+ +++PY+S  A        +    GA+  S ++A
Sbjct: 543 SNLKHRPQGIGMQGLHDVFMKLKIPYDSEMAFRLAALIQEAIYYGAVRESVKIA 596



 Score = 29.5 bits (63), Expect(2) = 6e-07
 Identities = 14/46 (30%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
 Frame = +3

Query: 255 AVCNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYY 389
           AVCNLA+I ++ FV+ +    +F+ + +      + +N +ID   Y
Sbjct: 462 AVCNLATICVSNFVNVETGEIDFEGIADAAGVACKGINNLIDKQNY 507


>UniRef50_Q6UDJ2 Cluster: Ribonucleoside-diphosphate reductase; n=3;
           Alphaherpesvirinae|Rep: Ribonucleoside-diphosphate
           reductase - Psittacid herpesvirus 1
          Length = 811

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 36/84 (42%), Positives = 53/84 (63%), Gaps = 1/84 (1%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186
           L+D +G+EFE  YE  E++N  +    A+ +  A+I++ V TGTP+++FK + NR     
Sbjct: 381 LSDLYGEEFEKEYELLERKNVGIATYPARDVMFALIKSAVSTGTPFVMFKHAVNRNYFFD 440

Query: 187 NLG-TIKCSNLCTEIVEYTSDDEV 255
             G  +KCSNLCTEIV  T D+ V
Sbjct: 441 MAGRAMKCSNLCTEIVHMTDDESV 464



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 9/113 (7%)
 Frame = +3

Query: 258 VCNLASIALNMFVDDNK---------TYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKK 410
           VCNL S+ L  FV             T+++   ++     T  +N ++ ++  P+  A  
Sbjct: 466 VCNLTSLNLAAFVTRRNALPGTPPIGTFDYSSFRDACAVATVFINALMSLSNLPIKRATT 525

Query: 411 SNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCEL 569
            N R R IGIGVQG   A +L     +S EA     K  +   +   + SC +
Sbjct: 526 GNERLRSIGIGVQGFHTACLLQGFGLDSVEACRFNGKLFEALALTTFQTSCRI 578


>UniRef50_Q91ES8 Cluster: ORF127 RR1; n=1; Cydia pomonella
           granulovirus|Rep: ORF127 RR1 - Cydia pomonella
           granulosis virus (CpGV) (Cydia pomonellagranulovirus)
          Length = 624

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 30/87 (34%), Positives = 49/87 (56%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186
           L DC+G+E+E LYE   +    +  V    LW  I+      G PY++++D+ N+ +NQ+
Sbjct: 218 LNDCYGEEYERLYEEMVRRGIQIKSVNVWELWGEIVNCLATNGYPYIVWRDTVNKYNNQQ 277

Query: 187 NLGTIKCSNLCTEIVEYTSDDEVQYAT 267
            LG +K  NLC E+ ++ +D  V   T
Sbjct: 278 ALGVVKTLNLCAEVCQHATDSTVDTNT 304


>UniRef50_A2DI13 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Trichomonas vaginalis G3|Rep: Ribonucleoside-diphosphate
           reductase - Trichomonas vaginalis G3
          Length = 614

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 38/103 (36%), Positives = 56/103 (54%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL +I L  FV D K  +FK L+EVT+T    L+ ++ +  +PV         +R IG+
Sbjct: 310 CNLGAINLEKFVVDGKI-DFKHLEEVTRTAIRMLDNVVSLTKFPVQRVTDMFTNNRRIGL 368

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCEL 569
           G+ GLAD   LM+LPY+S E      + +K     A++ S  L
Sbjct: 369 GIMGLADLLFLMKLPYDSEEGRACAEEVMKCVQDSAIDESKRL 411


>UniRef50_A6QCU9 Cluster: Ribonucleoside-diphosphate reductase,
           alpha subunit; n=15; Epsilonproteobacteria|Rep:
           Ribonucleoside-diphosphate reductase, alpha subunit -
           Sulfurovum sp. (strain NBC37-1)
          Length = 789

 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 32/81 (39%), Positives = 51/81 (62%), Gaps = 2/81 (2%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQ--VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           L + +G+EFE  Y   E  +  + +  + A+ LWK I+ +  ETG P++ FKD+ NR + 
Sbjct: 355 LTELYGEEFEKRYVELEHSDADITREVISAKGLWKEILRSYFETGNPFLTFKDAANRANP 414

Query: 181 QKNLGTIKCSNLCTEIVEYTS 243
            K++G I+ SNLCTEI + T+
Sbjct: 415 NKHVGIIRSSNLCTEIFQNTA 435



 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 35/107 (32%), Positives = 60/107 (56%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           +AVCNLASI L+      K +  + +  V  T    L+ +ID+N+YP+ + K++N + R 
Sbjct: 495 TAVCNLASINLS------KIHTKEDIARVVPTAVRMLDNVIDLNFYPLAKVKRTNEKSRS 548

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           IG+GV G A      ++ + S +    I++ ++  +  A+EAS  LA
Sbjct: 549 IGLGVMGEAQMLAENQIAWGSHDHFTKIDEVMESVSYYAIEASSNLA 595


>UniRef50_O26748 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Methanothermobacter thermautotrophicus str. Delta H|Rep:
           Ribonucleoside-diphosphate reductase - Methanobacterium
           thermoautotrophicum
          Length = 703

 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 37/104 (35%), Positives = 56/104 (53%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL S+ L++ V  +   N++KL+         L+ +IDVN YP+   ++  LR R IG+
Sbjct: 411 CNLGSVNLSLMVGPSGI-NWEKLRRTIHVAVHFLDNVIDVNSYPLRPVEEMTLRTRKIGL 469

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           GV G AD  I + +PY S  A+    + +   +  A  AS ELA
Sbjct: 470 GVMGFADMLIKLGIPYNSVAALEVAGRVMSFISSEARRASMELA 513



 Score = 39.9 bits (89), Expect = 0.058
 Identities = 19/54 (35%), Positives = 30/54 (55%)
 Frame = +1

Query: 58  KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219
           +    V  V ++V+ K I+EA   +G P +LF+D  NR +    LG I+ +N C
Sbjct: 213 RNGEVVDSVESRVILKRIVEAAWRSGDPGILFEDRINRYNPTPQLGRIEATNPC 266


>UniRef50_Q67SN6 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Firmicutes|Rep: Ribonucleoside-diphosphate reductase -
           Symbiobacterium thermophilum
          Length = 782

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 38/107 (35%), Positives = 62/107 (57%)
 Frame = +3

Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437
           VCNLASI L+      K +  +K+ EV       L+ +ID+N+YPVP+AK +N ++R IG
Sbjct: 510 VCNLASINLS------KVHTEEKIAEVVPLAIRMLDNVIDLNFYPVPQAKITNKKYRAIG 563

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
           +GV G       + + +ES + +   ++  +L    A++ S ELAA+
Sbjct: 564 LGVHGYHQMLAELGIHWESEDHLRKADEVFELLNYYAVKTSIELAAE 610



 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 33/83 (39%), Positives = 50/83 (60%), Gaps = 4/83 (4%)
 Frame = +1

Query: 7   LADCWGKEFESLY----ETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRK 174
           L D WG+E+E  Y    E    +      VRA+ + KA++++Q ETG P++ F+D+ NR 
Sbjct: 403 LEDAWGEEWERRYRLCVEAAHADKLDATVVRARQVAKAMLKSQYETGGPFLFFRDTVNRL 462

Query: 175 SNQKNLGTIKCSNLCTEIVEYTS 243
           +  K+ G + CSNLCTEI +  S
Sbjct: 463 NPNKHAGMVYCSNLCTEIAQNQS 485


>UniRef50_A0RYG3 Cluster: Ribonucleoside-diphosphate reductase; n=3;
           Crenarchaeota|Rep: Ribonucleoside-diphosphate reductase
           - Cenarchaeum symbiosum
          Length = 881

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 38/108 (35%), Positives = 60/108 (55%), Gaps = 4/108 (3%)
 Frame = +3

Query: 261 CNLASIALNMFV----DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           CNL SI L   V    D    +++++ +E+ +  T  L+ +IDVN YPV E  +++   R
Sbjct: 479 CNLGSINLARLVKRKADGEFEFDWQRYEEMIRKTTRFLDNVIDVNLYPVKEIDRASKESR 538

Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            IG+GV G+AD    +R+PY S E  +  +K  +  T  ++E S  LA
Sbjct: 539 RIGLGVMGVADLLYKLRIPYNSKEGYDLQSKLAEALTYYSMEESVALA 586


>UniRef50_P55982 Cluster: Ribonucleoside-diphosphate reductase
           subunit alpha; n=11; Campylobacterales|Rep:
           Ribonucleoside-diphosphate reductase subunit alpha -
           Helicobacter pylori (Campylobacter pylori)
          Length = 788

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 31/80 (38%), Positives = 50/80 (62%), Gaps = 1/80 (1%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQ 183
           L + +G++FE  Y  YEK+ + + + + A+ LWK I+    E G P++ FKD+ NR +  
Sbjct: 355 LTELYGQDFEKRYLEYEKDPKIIKEYINAKDLWKKILMNYFEAGLPFLAFKDNANRCNPN 414

Query: 184 KNLGTIKCSNLCTEIVEYTS 243
            + G I+ SNLCTEI + T+
Sbjct: 415 AHAGIIRSSNLCTEIFQNTA 434



 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 35/107 (32%), Positives = 59/107 (55%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           +AVCNLASI L+      K    + +K V   +   L+ +ID+N+YP  + K +NL++R 
Sbjct: 494 TAVCNLASINLS------KINTEEDIKRVVPIMVRLLDNVIDLNFYPNRKVKATNLQNRA 547

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           IG+GV G A      ++ + S E +  I+  ++  +  A++ S  LA
Sbjct: 548 IGLGVMGEAQMLAEHQIAWGSKEHLEKIDALMEQISYHAIDTSANLA 594


>UniRef50_Q647Z9 Cluster: Ribonucleoside-diphosphate reductase; n=3;
           cellular organisms|Rep: Ribonucleoside-diphosphate
           reductase - uncultured archaeon GZfos9C4
          Length = 914

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 36/104 (34%), Positives = 60/104 (57%), Gaps = 1/104 (0%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNK-TYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437
           CNL SI ++ FV       ++++L+EV     + L+ +IDVN YP+PE +K    +R IG
Sbjct: 608 CNLGSINVSKFVKSGDGEIDWERLREVICISVKFLDDVIDVNRYPLPEIEKMTKANRKIG 667

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCEL 569
           +G+ G A+  I + + Y+S +A++   K ++  T  A   S EL
Sbjct: 668 LGIMGFAELLIKLGIAYDSKDALSTGEKLMQFITNEARRCSTEL 711



 Score = 33.1 bits (72), Expect = 6.6
 Identities = 14/49 (28%), Positives = 29/49 (59%)
 Frame = +1

Query: 73  VXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219
           V +++A+ ++  I+    +TG P ++F D  NR++    +G I+ +N C
Sbjct: 242 VKRIKAREVFNEIVTYAWKTGDPGIVFMDEINRRNTIPAVGKIEATNPC 290


>UniRef50_Q6QXF6 Cluster: ORF37; n=4; Baculoviridae|Rep: ORF37 -
           Agrotis segetum granulosis virus (AsGV) (Agrotis
           segetumgranulovirus)
          Length = 615

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 31/87 (35%), Positives = 51/87 (58%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186
           L DC+G+E+ESLY    ++  +V ++ A  +   +I    E G PY++++D  N  +N +
Sbjct: 226 LNDCYGEEYESLYWRMVEKKLYVKKMYATQVLGELISCLTENGFPYVVWRDHVNMFNNHR 285

Query: 187 NLGTIKCSNLCTEIVEYTSDDEVQYAT 267
           +LGTI+  NLCTEI ++   D     T
Sbjct: 286 DLGTIQTLNLCTEICQHAGSDSSSMCT 312


>UniRef50_Q6AJC4 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Desulfotalea psychrophila|Rep:
           Ribonucleoside-diphosphate reductase - Desulfotalea
           psychrophila
          Length = 785

 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 32/80 (40%), Positives = 50/80 (62%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL SI L  FV +++  ++ +L ++ KT T  L+ +ID N +P+PE  +  L+ R IG+
Sbjct: 346 CNLGSINLGNFVKNDEV-DYSRLGQIVKTATCFLDNVIDCNVFPIPEIGEMTLKTRKIGL 404

Query: 441 GVQGLADAFILMRLPYESPE 500
           G+ GL D  I + +PY S E
Sbjct: 405 GIMGLHDLLIQLAIPYGSEE 424


>UniRef50_Q6VMN2 Cluster: Ribonucleoside-diphosphate reductase;
           n=10; Tortoise herpesvirus|Rep:
           Ribonucleoside-diphosphate reductase - Tortoise
           herpesvirus
          Length = 796

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 35/82 (42%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186
           LA  +GKEFE  Y   E     V Q+  + L   II + + TG+P+++FKDSCNR     
Sbjct: 355 LAKLYGKEFEDEYHRLETAGMAVRQMPIKELLFKIIRSAIMTGSPFIMFKDSCNRHYYMD 414

Query: 187 NLG-TIKCSNLCTEIVEYTSDD 249
             G  I+ SNLCTEI+ +T  D
Sbjct: 415 TQGQAIRGSNLCTEIIHHTEPD 436



 Score = 39.5 bits (88), Expect = 0.076
 Identities = 25/89 (28%), Positives = 42/89 (47%)
 Frame = +3

Query: 303 NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRL 482
           ++ +NF+KL E     T  +N +ID + +P  + +      R +GIG QGL     ++  
Sbjct: 481 HRYFNFEKLTEAVTAATIFINVMIDRSVHPTTKTQNGAKNFRSMGIGFQGLNTLCWILGE 540

Query: 483 PYESPEAIN*INKYLKLFTMGALEASCEL 569
              +P+A        +   + A EAS EL
Sbjct: 541 TLVTPKARKLGKTICEAMYLSAAEASNEL 569


>UniRef50_A5FSC1 Cluster: Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent; n=36; cellular
           organisms|Rep: Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent - Dehalococcoides sp. BAV1
          Length = 866

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 37/109 (33%), Positives = 58/109 (53%), Gaps = 3/109 (2%)
 Frame = +3

Query: 261 CNLASIALNMFVD---DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           CNL SI L+  V       T ++KKL  V K+    L+ +IDVN +P+P+ ++   + R 
Sbjct: 406 CNLGSINLSRMVTVSGGQNTVDYKKLSRVIKSAVRFLDNVIDVNKFPLPQIEEMTKKSRK 465

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
           IG+GV G AD  + + +PY S  +I    + +      A + S ELA +
Sbjct: 466 IGLGVMGFADMLLELGVPYNSENSIKLAEEIMCFVNDEAHKFSSELAVE 514


>UniRef50_Q9UYA0 Cluster: Ribonucleoside-diphosphate reductase; n=2;
            Pyrococcus|Rep: Ribonucleoside-diphosphate reductase -
            Pyrococcus abyssi
          Length = 2122

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 42/110 (38%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
 Frame = +3

Query: 261  CNLASIALNMFV--DDN-KTY-NFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
            CNLASI L  FV  D+N K Y ++ +   V + + + L+  IDVN +P+PE   +    R
Sbjct: 1691 CNLASINLAKFVKYDENGKPYFDWDEYAYVIQKVAKYLDNSIDVNKFPLPEIDYNTKLTR 1750

Query: 429  PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
             IG+G+ GLADA   + +PY S E    + K  +  T  A + S E A K
Sbjct: 1751 RIGVGMMGLADALFKLGIPYNSEEGFKFMRKVTEYLTFYAYKYSIEAAKK 1800


>UniRef50_P95484 Cluster: Ribonucleoside-diphosphate reductase; n=2;
            Thermococcaceae|Rep: Ribonucleoside-diphosphate reductase
            - Pyrococcus furiosus
          Length = 1740

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 42/110 (38%), Positives = 60/110 (54%), Gaps = 4/110 (3%)
 Frame = +3

Query: 261  CNLASIALNMFV--DDN-KTY-NFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
            CNLASI L  FV  D+N K Y ++ +   V + + + L+  IDVN +P+PE   +    R
Sbjct: 1308 CNLASINLAKFVKYDENGKPYFDWDEYAYVIQKVAKYLDNSIDVNKFPLPEIDYNTKLTR 1367

Query: 429  PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
             IG+G+ GLADA   + +PY S E    + K  +  T  A + S E A K
Sbjct: 1368 RIGVGMMGLADALFKLGIPYNSEEGFKFMRKVTEYLTFYAYKYSVEAAKK 1417


>UniRef50_A3QTY4 Cluster: Ribonucleotide reductase large subunit;
           n=1; Oryctes rhinoceros virus|Rep: Ribonucleotide
           reductase large subunit - Oryctes rhinoceros virus
          Length = 737

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 29/79 (36%), Positives = 47/79 (59%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186
           L +  G E++ +Y+ + + N +  +V +  L   ++    ETG+PY+++ D+ NR SN K
Sbjct: 328 LCEFTGDEYKRMYKRFVEANLYTNKVSSSALMDDLVTCISETGSPYVVWSDNVNRFSNHK 387

Query: 187 NLGTIKCSNLCTEIVEYTS 243
           +LG IK  NLC EI  Y S
Sbjct: 388 HLGKIKTLNLCAEIANYAS 406


>UniRef50_Q8VKI9 Cluster: Ribonucleoside-diphosphate reductase;
           n=13; Mycobacterium|Rep: Ribonucleoside-diphosphate
           reductase - Mycobacterium tuberculosis
          Length = 735

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 36/104 (34%), Positives = 56/104 (53%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL SI L   + D +  ++ +L+EV       L+ +IDV+ YP PE  ++    R IG+
Sbjct: 431 CNLGSINLARMLADGRV-DWDRLEEVAGVAVRFLDDVIDVSRYPFPELGEAARATRKIGL 489

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           GV GLA+    + +PY+S EA+    + ++     A  AS  LA
Sbjct: 490 GVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLA 533



 Score = 32.7 bits (71), Expect = 8.8
 Identities = 17/57 (29%), Positives = 30/57 (52%)
 Frame = +1

Query: 58  KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEI 228
           +  + V ++ A  L+ AI +A    G P ++F D+ NR +     G I+ +N C E+
Sbjct: 367 RTGKIVARMPAAELFDAICKAAHAGGDPGLVFLDTINRANPVPGRGRIEATNPCGEV 423


>UniRef50_O83972 Cluster: Ribonucleoside-diphosphate reductase
           subunit alpha; n=13; Bacteria|Rep:
           Ribonucleoside-diphosphate reductase subunit alpha -
           Treponema pallidum
          Length = 845

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 37/106 (34%), Positives = 59/106 (55%), Gaps = 1/106 (0%)
 Frame = +3

Query: 258 VCNLASIAL-NMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
           VCNLAS+ L N+ + D+K     +L+EV +     L+ +ID+ YYPVP A+ +N  +R I
Sbjct: 573 VCNLASLVLSNIDLSDDK-----ELREVVRVAVRALDNVIDLTYYPVPYAQVTNAYYRAI 627

Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           G+GV G         + +ES E +   ++  +     A+EAS  +A
Sbjct: 628 GLGVSGYHHVLAQQGIDWESDEHLAFADRIFERINRAAIEASMTIA 673



 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 28/80 (35%), Positives = 46/80 (57%), Gaps = 1/80 (1%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQ 183
           L D + +E+E  Y    K+ R   + +  + L + ++++ VETGTP+  ++D  NR +  
Sbjct: 465 LEDFYAEEWEKRYWDCVKDARISKRTIPIKELVRLVLKSVVETGTPFAFYRDHANRANPN 524

Query: 184 KNLGTIKCSNLCTEIVEYTS 243
            + G I CSNLCTEI +  S
Sbjct: 525 GHRGIIYCSNLCTEIAQNMS 544


>UniRef50_O66503 Cluster: Ribonucleoside-diphosphate reductase
           subunit alpha; n=1; Aquifex aeolicus|Rep:
           Ribonucleoside-diphosphate reductase subunit alpha -
           Aquifex aeolicus
          Length = 801

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 33/82 (40%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
 Frame = +1

Query: 4   GLADCWGKEFESLYETYEKE--NRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKS 177
           GL D +G+EFE  Y   E+   +    +V +  LWK ++    ETG PY+ F+D  NRK+
Sbjct: 412 GLEDFYGEEFEKWYLELEENLPSYAKKKVNSFELWKRLLTVAFETGEPYIFFRDEANRKN 471

Query: 178 NQKNLGTIKCSNLCTEIVEYTS 243
             K+ G +  SNLC EIV+  S
Sbjct: 472 PNKHTGMVYSSNLCHEIVQTMS 493



 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 36/105 (34%), Positives = 58/105 (55%)
 Frame = +3

Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437
           VCNL S+ L       K +  +++KEV   +   L+ +I++N+Y +PEA+ +N R+R IG
Sbjct: 520 VCNLGSVNLG------KVHTEEEIKEVLPLLVRMLDNVIEMNFYAIPEAEYTNKRYRAIG 573

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           IGV       +   + +ES E +   +K  +L    AL+ S ELA
Sbjct: 574 IGVSNYHYCLVKNGIKWESEEHLKFADKLFELIAFYALKGSLELA 618


>UniRef50_Q2VSI0 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Ovine herpesvirus 2|Rep: Ribonucleoside-diphosphate
           reductase - Ovine herpesvirus 2
          Length = 785

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 30/82 (36%), Positives = 50/82 (60%), Gaps = 1/82 (1%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186
           L   +G+EF+  YE   +E R+V QV  + L  +II   ++TG+PY+++KD+CN    ++
Sbjct: 329 LPHLYGEEFKEEYERLVRERRYVGQVIIKSLLFSIINTIIKTGSPYIIYKDACNAHHWKE 388

Query: 187 NLG-TIKCSNLCTEIVEYTSDD 249
             G  I  +NLC E+++Y   D
Sbjct: 389 MRGQAIASANLCAEVIQYPGRD 410



 Score = 33.1 bits (72), Expect = 6.6
 Identities = 17/37 (45%), Positives = 19/37 (51%)
 Frame = +3

Query: 393 VPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEA 503
           V E  +   R R +GIGV GLAD F  M   Y  P A
Sbjct: 481 VTEGMQRGQRERSMGIGVHGLADVFAEMGYSYLDPAA 517


>UniRef50_Q5KX82 Cluster: Ribonucleoside-diphosphate reductase; n=8;
           Firmicutes|Rep: Ribonucleoside-diphosphate reductase -
           Geobacillus kaustophilus
          Length = 857

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 39/107 (36%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
 Frame = +3

Query: 255 AVCNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           +VCNLA+I L   VD + K  +++KLK   +      + +ID   Y + E KK  L  R 
Sbjct: 487 SVCNLAAINLANMVDKERKVIDYEKLKRTVEIGVRMQDNVIDATPYFLEENKKQALGERR 546

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           IG+GV GLAD  I     Y S E    +++  +     A  AS ELA
Sbjct: 547 IGLGVMGLADLLIYCEKAYGSEEGNQLVDELFRTIATTAYRASIELA 593


>UniRef50_A0B8R8 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Methanomicrobia|Rep: Ribonucleoside-diphosphate
           reductase - Methanosaeta thermophila (strain DSM 6194 /
           PT) (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 688

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 32/103 (31%), Positives = 56/103 (54%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL S+ L+  V+  +  ++ +L+E  +     L+ +ID N +P+ + + + LR R IG+
Sbjct: 394 CNLGSVNLSRMVERGEI-SWDRLEETVRLAVRFLDDVIDANRFPLKQIEDATLRTRKIGL 452

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCEL 569
           GV G A+  I + + Y S +A+    + +   T  A E SC L
Sbjct: 453 GVMGFAEMLIQLGVSYASQDALRIAEELMAFITKTAREESCAL 495


>UniRef50_P74240 Cluster: Ribonucleoside-diphosphate reductase
           subunit alpha; n=2; Chroococcales|Rep:
           Ribonucleoside-diphosphate reductase subunit alpha -
           Synechocystis sp. (strain PCC 6803)
          Length = 767

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 31/77 (40%), Positives = 45/77 (58%), Gaps = 4/77 (5%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKEN----RFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRK 174
           LA+ WG++FE  Y   E           ++ A+ L+K I+  QVETG PY+ FKD+ N+ 
Sbjct: 388 LAELWGEQFEGAYREIESNLDTTITLYKRINARELFKQIMRTQVETGMPYLSFKDTINKA 447

Query: 175 SNQKNLGTIKCSNLCTE 225
           +  K+LG I  +NLC E
Sbjct: 448 NPNKHLGYIPGTNLCCE 464



 Score = 39.5 bits (88), Expect = 0.076
 Identities = 25/83 (30%), Positives = 39/83 (46%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL S+ L          + + +  V++     L+  I++   P  +AK  N ++R IG+
Sbjct: 478 CNLVSLNL-------ANLDLQDIAGVSQIAVRMLDNTIELTAPPFADAKSHNNKYRTIGV 530

Query: 441 GVQGLADAFILMRLPYESPEAIN 509
           G  GLAD     RL Y+    IN
Sbjct: 531 GAMGLADWLAKRRLNYDELADIN 553


>UniRef50_Q18UV0 Cluster: Ribonucleoside-diphosphate reductase; n=4;
           Bacteria|Rep: Ribonucleoside-diphosphate reductase -
           Desulfitobacterium hafniense (strain DCB-2)
          Length = 1153

 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 3/107 (2%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNK---TYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           CNL SI L + V +       ++++L ++T+  T  L+ +I+ N YP+P  ++    +R 
Sbjct: 661 CNLGSINLKLMVTEKNGKVVVDWERLGQITRLATRFLDNVIEANTYPLPSIEEMVKGNRK 720

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           IG+GV G AD  IL++  Y S +A+    K +      A   S  LA
Sbjct: 721 IGLGVMGFADMLILLQTSYASEDAVEYAEKVMNFIQTEARLESQRLA 767


>UniRef50_Q4C9K9 Cluster: Ribonucleoside-diphosphate reductase; n=4;
           Cyanobacteria|Rep: Ribonucleoside-diphosphate reductase
           - Crocosphaera watsonii
          Length = 1116

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 31/75 (41%), Positives = 46/75 (61%), Gaps = 4/75 (5%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYE----KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRK 174
           LA+ WG++FE  Y   E    +E     +V A+ L+K I+ +QVETG PY+ FKD+ N+ 
Sbjct: 390 LAELWGEKFEEAYGLIEAELDREITLYKRVNARELFKTIMRSQVETGMPYLAFKDTINKA 449

Query: 175 SNQKNLGTIKCSNLC 219
           +  K++G I   NLC
Sbjct: 450 NPNKHVGYIPGVNLC 464



 Score = 39.1 bits (87), Expect = 0.10
 Identities = 26/78 (33%), Positives = 38/78 (48%)
 Frame = +3

Query: 261  CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
            CNL S+ L    ++   Y    L  ++  I +N    ID+   P  +AK  N R+R +G+
Sbjct: 827  CNLVSLNLANIEEEELDY----LCNISVRILDNT---IDITNPPFNDAKAHNDRYRTVGV 879

Query: 441  GVQGLADAFILMRLPYES 494
            G  GLAD      L YE+
Sbjct: 880  GCMGLADWLAKKGLTYEN 897


>UniRef50_Q97ZH9 Cluster: Ribonucleoside-diphosphate reductase; n=4;
           Sulfolobaceae|Rep: Ribonucleoside-diphosphate reductase
           - Sulfolobus solfataricus
          Length = 841

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 37/107 (34%), Positives = 56/107 (52%), Gaps = 3/107 (2%)
 Frame = +3

Query: 261 CNLASIALNMFV---DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           CNL SI L  FV   D     ++  L E+ +     L+ +ID N YP+ + + +  R R 
Sbjct: 464 CNLGSINLEKFVIERDGKAAIDWDGLAEIIRYGVRFLDNVIDANRYPLKQIEDATKRTRK 523

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           +G+GV GLA  FI + + Y+S +AI    +  K     A +AS E+A
Sbjct: 524 VGLGVMGLARMFIKLGIAYDSVDAIYLSYQLAKFIFYHAYKASIEIA 570



 Score = 37.5 bits (83), Expect = 0.31
 Identities = 20/56 (35%), Positives = 30/56 (53%)
 Frame = +1

Query: 58  KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           KE   V  V A+ L+  I++   ++G P +LF D+ NR+     LG I  +N C E
Sbjct: 400 KEGAVVKYVNAKSLFDEIVKGAWDSGDPGLLFIDTINRRHPVWYLGKINATNPCGE 455


>UniRef50_UPI00015BC77F Cluster: UPI00015BC77F related cluster; n=1;
           unknown|Rep: UPI00015BC77F UniRef100 entry - unknown
          Length = 1005

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 30/90 (33%), Positives = 50/90 (55%)
 Frame = +3

Query: 303 NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRL 482
           N T++++K K V +     L+ +ID NYY +   +K   + R IG+G  G  D    ++L
Sbjct: 513 NNTFDWEKFKAVIRKAIRFLDNVIDANYYALEAVEKGTKQSRKIGLGFMGYQDMIEKLKL 572

Query: 483 PYESPEAIN*INKYLKLFTMGALEASCELA 572
           P +S EA+  ++K  +  +  A+E S ELA
Sbjct: 573 PVDSKEALKLLDKIGETMSYVAIETSVELA 602



 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 4/90 (4%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVX----QVRAQVLWKAIIEAQVETGTPYMLFKDSCN 168
           P L   +GK+F   Y    ++         +++A  L+K  IE  ++TG P+  FKD  N
Sbjct: 383 PKLVSTYGKKFSREYSKCIRKALSGKIRHKKIKAVELFKEAIENTIQTGEPWYTFKDPIN 442

Query: 169 RKSNQKNLGTIKCSNLCTEIVEYTSDDEVQ 258
            +   K+ GTI  +NLCTE +  ++ D ++
Sbjct: 443 IRHPNKHTGTILTTNLCTEQLLVSTYDSIE 472


>UniRef50_Q5SM68 Cluster: Ribonucleoside-diphosphate reductase; n=5;
            Thermus thermophilus|Rep: Ribonucleoside-diphosphate
            reductase - Thermus thermophilus (strain HB8 / ATCC 27634
            / DSM 579)
          Length = 2202

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 32/104 (30%), Positives = 59/104 (56%)
 Frame = +3

Query: 261  CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
            C+L ++ L  +V D + +  ++ +   +T    L+ ++DVN + +P+ + +  + R +G+
Sbjct: 1306 CDLGAMNLAAYVKDGE-FQMEEFRRDVRTAIRFLDNVLDVNKFALPDNEMAAKKLRRLGL 1364

Query: 441  GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            G+ GLADA I M LPY+S EA   + + +      A+ AS  LA
Sbjct: 1365 GLMGLADALIKMGLPYDSEEARRKVYEIVSAMREEAIRASEALA 1408


>UniRef50_A5TVY2 Cluster: Ribonucleoside-diphosphate reductase; n=3;
           Fusobacterium nucleatum|Rep: Ribonucleoside-diphosphate
           reductase - Fusobacterium nucleatum subsp. polymorphum
           ATCC 10953
          Length = 755

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 29/75 (38%), Positives = 46/75 (61%), Gaps = 2/75 (2%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQ--VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           L + +G EFE+LYE  E +     +  + A+ L+K+I++ Q+ETG PY+ FKD  N  ++
Sbjct: 369 LCELYGYEFENLYEKIENDPNIKLKKVLSAKELFKSIMKTQLETGMPYIFFKDRANEVNH 428

Query: 181 QKNLGTIKCSNLCTE 225
             ++G I   NLC E
Sbjct: 429 NSHMGMIGNGNLCME 443



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 34/104 (32%), Positives = 52/104 (50%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL SI L     +       +L++        L+  ID+   P+ E+ K NL +R IG+
Sbjct: 475 CNLISINLAELTSE-------ELEKHVALAVRALDNTIDLTVTPLKESNKHNLLYRTIGV 527

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           G  GLAD      + YE  E+IN IN+  +   + +++AS  LA
Sbjct: 528 GAMGLADYLAREYMIYE--ESINEINELFERIALYSIKASALLA 569


>UniRef50_Q9IBT4 Cluster: Ribonucleoside-diphosphate reductase; n=6;
           Mardivirus|Rep: Ribonucleoside-diphosphate reductase -
           Meleagrid herpesvirus 1 (MeHV-1) (Turkey herpesvirus)
          Length = 822

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 31/73 (42%), Positives = 43/73 (58%), Gaps = 1/73 (1%)
 Frame = +1

Query: 25  KEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLG-TI 201
           +EFE  YE  E E   V  +  + +  AII++   TG+P++LFKD+CNR       G  I
Sbjct: 407 EEFEKEYERLESEGLGVASIPIRDMMFAIIKSAASTGSPFILFKDACNRHYITNTQGDAI 466

Query: 202 KCSNLCTEIVEYT 240
             SNLCTEI++ T
Sbjct: 467 AGSNLCTEIIQKT 479



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
 Frame = +3

Query: 252 SAVCNLASIALNMFV---DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422
           + VC+LASI L   V   D N+ ++F  L+   +  T  +N I++ +  P  ++     R
Sbjct: 484 NGVCSLASINLARCVRNIDGNRQFDFDALRYAVRLATVFVNAIMEGSDVPTEKSHSGRER 543

Query: 423 HRPIGIGVQGLADAFILMRLPYESPEAIN*INKYL-KLFTMGALEASCELAAK 578
           +R +GIGVQG   AF+ M L     E    +NK + +   + A+  SCE   +
Sbjct: 544 NRSMGIGVQGFHTAFLSMGLDL-CDERARSLNKLIFEFMLLEAMTVSCEFCER 595


>UniRef50_Q5LNK9 Cluster: Ribonucleoside-diphosphate reductase,
           putative; n=22; Alphaproteobacteria|Rep:
           Ribonucleoside-diphosphate reductase, putative -
           Silicibacter pomeroyi
          Length = 760

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 34/103 (33%), Positives = 53/103 (51%)
 Frame = +3

Query: 264 NLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIG 443
           NLA +  N F +D    + + L+++  T    ++ ++D + +P+PE        R IG+G
Sbjct: 285 NLARLVSNPF-EDAAELDPEALQKLVATAVRMMDNVVDASRFPLPEQAAEAQNKRRIGLG 343

Query: 444 VQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           V GLADA +++ L Y S EA      +L      A  AS ELA
Sbjct: 344 VTGLADALLMLGLRYGSDEAAKQTEDWLHAIARAAYLASVELA 386



 Score = 34.3 bits (75), Expect = 2.9
 Identities = 16/48 (33%), Positives = 25/48 (52%)
 Frame = +1

Query: 82  VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           V A+ LW  I++A  +   P ++F D  N  +N   + TI  +N C E
Sbjct: 223 VEARTLWNKIMQATYDYAEPGVIFIDRINAANNLNYVETIAATNPCGE 270


>UniRef50_A3H704 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Caldivirga maquilingensis IC-167|Rep:
           Ribonucleoside-diphosphate reductase - Caldivirga
           maquilingensis IC-167
          Length = 877

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 33/104 (31%), Positives = 54/104 (51%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL SI L  +++ N + ++  L          L+ +ID N +P     ++N   R IG+
Sbjct: 486 CNLGSINLTKYINGN-SIDWVSLANDIMLAVRFLDDVIDSNQHPHEYLDRANKASRRIGL 544

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           G+ G AD  + + +PY+SP+AI   +  +      A+ AS ELA
Sbjct: 545 GINGWADVLVSLDIPYDSPKAIALADVVMGFVARVAVRASVELA 588


>UniRef50_A3JKM6 Cluster: Ribonucleoside reductase; n=1;
           Marinobacter sp. ELB17|Rep: Ribonucleoside reductase -
           Marinobacter sp. ELB17
          Length = 1087

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           C L S+ L MFVDD  T    +N++K K+V    T  L+ ++++N  P+ + +      R
Sbjct: 706 CLLGSVNLTMFVDDPFTDKASFNYEKYKKVVGIFTRMLDNVVEINGLPLAQQRHEITYKR 765

Query: 429 PIGIGVQGLADAFILMRLPYESPEAI 506
             G+G+ GL     ++R+PY S E++
Sbjct: 766 RHGMGILGLGSTLAMLRMPYGSEESV 791


>UniRef50_Q9PE32 Cluster: Ribonucleoside-diphosphate reductase;
           n=34; root|Rep: Ribonucleoside-diphosphate reductase -
           Xylella fastidiosa
          Length = 830

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 27/69 (39%), Positives = 44/69 (63%), Gaps = 1/69 (1%)
 Frame = +1

Query: 31  FESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKC 207
           F   YE    + R   + V+A  ++K I+ +Q+ETG P+M ++D  NRK+  K++G +  
Sbjct: 456 FRRKYEDVVADERISRKTVKAIDIFKRIMVSQLETGNPFMFYRDEVNRKNPNKHVGMVYS 515

Query: 208 SNLCTEIVE 234
           SNLCTEI++
Sbjct: 516 SNLCTEILQ 524



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 1/106 (0%)
 Frame = +3

Query: 258 VCNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
           VCNL+SI L   +           L+ +       L+ +ID+N  PVP+A  +N ++R I
Sbjct: 552 VCNLSSINLGRAITVQADLLGADVLERLIPIQVRMLDNVIDLNLLPVPQATITNQKYRAI 611

Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           G+G  G         + + SPEA    +   +      + AS ELA
Sbjct: 612 GLGTFGWHHLLAQKAIHWNSPEAEQYSDALYERINYLTIRASMELA 657


>UniRef50_A1YJD3 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Spodoptera frugiperda MNPV|Rep:
           Ribonucleoside-diphosphate reductase - Spodoptera
           frugiperda nuclear polyhedrosis virus (SfNPV)
          Length = 839

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 34/103 (33%), Positives = 63/103 (61%), Gaps = 2/103 (1%)
 Frame = +3

Query: 270 ASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGV 446
           AS+A++  V+ + K +++  L+ +TK +  +L+ +I++N YP+   K  N +H  I +G+
Sbjct: 519 ASVAVDKCVNLETKQFDYNLLRRITKNVVRDLDAMININMYPLD--KFENKKHN-IAVGM 575

Query: 447 QGLADAFILMRLPYESPEAIN*INKYL-KLFTMGALEASCELA 572
           QG A+  +L+   ++  EA   +NK + +    GA+EAS ELA
Sbjct: 576 QGFAETLLLLGYTFDMVEA-KALNKLIAETIYYGAIEASNELA 617



 Score = 35.1 bits (77), Expect = 1.6
 Identities = 19/54 (35%), Positives = 30/54 (55%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCN 168
           L+  +G +FE  Y  +EKE+     V+A+ L K II+     G   ++FKD+ N
Sbjct: 448 LSSKYGDKFEQAYVKFEKEHINAKIVKAKDLLKLIIDTMRINGNLSVMFKDTFN 501


>UniRef50_O33839 Cluster: Ribonucleoside-diphosphate reductase; n=4;
           Thermotogaceae|Rep: Ribonucleoside-diphosphate reductase
           - Thermotoga maritima
          Length = 827

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 31/103 (30%), Positives = 52/103 (50%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL SI +  F + N   + + L+E+ +     L+ +IDVN +P+ +  K+    R +G+
Sbjct: 333 CNLGSIDVAKFYN-NGFVDLEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGL 391

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCEL 569
           G+ G AD    + +PY S EA +     +    + A   S EL
Sbjct: 392 GIMGFADLLYKLEIPYNSQEARDFAANLMAFIALHAHRTSYEL 434


>UniRef50_A7I485 Cluster: Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent; n=1; Candidatus
           Methanoregula boonei 6A8|Rep: Ribonucleoside-diphosphate
           reductase, adenosylcobalamin-dependent - Methanoregula
           boonei (strain 6A8)
          Length = 741

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 32/107 (29%), Positives = 59/107 (55%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           C L SI L   V +   ++   L++ ++  T  L+ +I+ N +P+P+  ++  + R IG+
Sbjct: 266 CVLGSINLAACVREG-AFDEDLLRDTSRMATRFLDLVIEKNVFPIPQIAEATRKTRKIGL 324

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKV 581
           GV G+ DA +++ L Y+S +        +K+ T  A+E S  LA K+
Sbjct: 325 GVMGVHDAMLMLGLSYDSEKGRAWCEWVMKVITETAIEESHRLAEKL 371



 Score = 35.1 bits (77), Expect = 1.6
 Identities = 16/43 (37%), Positives = 22/43 (51%)
 Frame = +1

Query: 97  LWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           +W  I+E   + G P +LF D  NR +    LG I  +N C E
Sbjct: 215 IWNGIVEGIWKNGEPGILFYDEINRHNPTPQLGEIDTTNPCGE 257


>UniRef50_Q5P1D5 Cluster: Ribonucleotide reductase, Coenzyme
           B12-dependent; n=6; Betaproteobacteria|Rep:
           Ribonucleotide reductase, Coenzyme B12-dependent -
           Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
           (strain EbN1))
          Length = 963

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 36/131 (27%), Positives = 60/131 (45%), Gaps = 4/131 (3%)
 Frame = +3

Query: 261 CNLASIALNMFVD----DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           C+L SI L  F+     D   +++    +V       L+ ++DV ++P+P+ +      R
Sbjct: 312 CDLGSINLTPFIKHPFTDKAEFDYPAFGKVVDVAIRMLDNVLDVTHWPLPQQENEAQSKR 371

Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTD 608
            +G+G  GL DA I++   Y+SP+A     K  +     A  AS ELA +     +   D
Sbjct: 372 RVGLGFTGLGDALIMLCKRYDSPDARAVATKISEYMRDRAYLASVELAKERGAFPLFNAD 431

Query: 609 APASRGHITVR 641
              S G+   R
Sbjct: 432 LYLSGGNFASR 442


>UniRef50_Q2RP92 Cluster: Ribonucleotide reductase large subunit;
           n=1; Rhodospirillum rubrum ATCC 11170|Rep:
           Ribonucleotide reductase large subunit - Rhodospirillum
           rubrum (strain ATCC 11170 / NCIB 8255)
          Length = 786

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 4/110 (3%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           CNL  + L + V D  T    ++  +L EV       L+ ++DV+ +PV +  K     R
Sbjct: 296 CNLGCVNLAVLVRDPFTPQARFDDARLAEVAAIGVRFLDNVLDVSNFPVEDQAKEAQAKR 355

Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
            +G+G+ GL +A  ++ L Y SP AI    + + L    A  AS ELA +
Sbjct: 356 RLGLGIMGLGNALQMLGLRYGSPAAIAETRRIMALLRDAAYRASAELAGE 405



 Score = 36.7 bits (81), Expect = 0.54
 Identities = 16/49 (32%), Positives = 26/49 (53%)
 Frame = +1

Query: 79  QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           ++ A+ LW+ II    +   P ++F D  N ++N     TI C+N C E
Sbjct: 239 RLSARALWEKIIRTTYDHAEPGVIFIDRVNERNNLAYCETISCTNPCGE 287


>UniRef50_A6NX38 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Bacteroides capillosus ATCC 29799|Rep:
           Ribonucleoside-diphosphate reductase - Bacteroides
           capillosus ATCC 29799
          Length = 784

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 3/107 (2%)
 Frame = +3

Query: 261 CNLASIAL--NMFVDDNKTYNFK-KLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           CNL SI L  ++  +D +    K KL    +T    L+ +I+VN YP+PE        R 
Sbjct: 282 CNLGSINLVTHLKEEDGRWVLDKDKLTATIRTAVHFLDNVIEVNKYPLPEIDAMTRSTRK 341

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           IG+GV G AD  + M +PY S + +    + ++L      E S  LA
Sbjct: 342 IGLGVMGFADMLLYMGIPYNSDQGVAMAREVMELVNTIGHEESQALA 388


>UniRef50_Q9YA77 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Desulfurococcales|Rep: Ribonucleoside-diphosphate
           reductase - Aeropyrum pernix
          Length = 979

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 26/82 (31%), Positives = 49/82 (59%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL S++++ +V   + ++ ++     + +TE ++ +ID+N +P      +N   R IG+
Sbjct: 478 CNLGSLSVDKYVAGGR-FDLERFANDVEFLTEAMDAVIDLNRHPDERQDTANKFTRKIGL 536

Query: 441 GVQGLADAFILMRLPYESPEAI 506
           G+ GLADA   +  PY+S EA+
Sbjct: 537 GIMGLADALAGLGYPYDSEEAV 558



 Score = 34.3 bits (75), Expect = 2.9
 Identities = 16/50 (32%), Positives = 28/50 (56%)
 Frame = +1

Query: 88  AQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVEY 237
           A+ +W+ I+EA    G P +++ D+ N+ S    LG +  +N C+E   Y
Sbjct: 424 AREIWREIVEAAWGGGDPGLVYFDNHNKWSPTPWLGAVNATNPCSEQTLY 473


>UniRef50_P09853 Cluster: Ribonucleoside-diphosphate reductase large
           chain; n=9; Simplexvirus|Rep: Ribonucleoside-diphosphate
           reductase large chain - Human herpesvirus 2 (strain 333)
           (HHV-2) (Human herpes simplex virus2)
          Length = 1144

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 35/80 (43%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186
           LAD  G+EFE LYE  E    F   +  Q L  AI+ +   TG+P+++FKD+ NR     
Sbjct: 730 LADFHGEEFEKLYEHLEAMG-FGETIPIQDLAYAIVRSAATTGSPFIMFKDAVNRHYIYD 788

Query: 187 NLG-TIKCSNLCTEIVEYTS 243
             G  I  SNLCTEIV  +S
Sbjct: 789 TQGAAIAGSNLCTEIVHPSS 808



 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 32/109 (29%), Positives = 54/109 (49%)
 Frame = +3

Query: 252  SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
            S VCNL S+ L   V   +T++F  L++  +     +N +ID    P P+  + +   R 
Sbjct: 812  SGVCNLGSVNLARCVS-RRTFDFGMLRDAVQACVLMVNIMIDSTLQPTPQCARGHDNLRS 870

Query: 432  IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
            +GIG+QGL  A + M L  ES E  +      ++  + A++ S  L  +
Sbjct: 871  MGIGMQGLHTACLKMGLDLESAEFRDLNTHIAEVMLLAAMKTSNALCVR 919


>UniRef50_A7KUZ9 Cluster: Nrd alpha subunit; n=1; Bacillus phage
           0305phi8-36|Rep: Nrd alpha subunit - Bacillus phage
           0305phi8-36
          Length = 767

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 36/105 (34%), Positives = 54/105 (51%)
 Frame = +3

Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437
           VCNLAS+ L   V          L  V + +T  L+ IID+N   V +A  +N R+RPIG
Sbjct: 495 VCNLASVNLAKAVPAGV------LARVIRIVTRMLDNIIDINTISVLQAGITNKRYRPIG 548

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           +G  G      ++ L +ES  A+N  +   + F    +++S ELA
Sbjct: 549 MGAYGWHHLLAILGLDWESEAAVNYADTLYEEFAYHVIDSSVELA 593



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 24/55 (43%), Positives = 33/55 (60%), Gaps = 5/55 (9%)
 Frame = +1

Query: 85  RAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNL-----GTIKCSNLCTEIVE 234
           RA  +   I+E Q+ETG PYM ++D  NR +  K++       I CSNLCTEI +
Sbjct: 412 RAMDIMVRIMEIQLETGMPYMFYRDQVNRMNPNKHVHGIGRTAIYCSNLCTEIAQ 466


>UniRef50_A7HK53 Cluster: Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent; n=1; Fervidobacterium
           nodosum Rt17-B1|Rep: Ribonucleoside-diphosphate
           reductase, adenosylcobalamin-dependent -
           Fervidobacterium nodosum Rt17-B1
          Length = 841

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 27/80 (33%), Positives = 45/80 (56%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL SI +  F  + + Y ++   + T+     L+ +IDVN +P+ + +K+    R IG+
Sbjct: 339 CNLGSIDVAKFYMNGEFY-WEAFAQATRLAVRFLDDVIDVNVFPLEKIRKAVTDSRRIGL 397

Query: 441 GVQGLADAFILMRLPYESPE 500
           G+ G AD   +M +PY S E
Sbjct: 398 GIMGFADLLYMMDIPYNSHE 417


>UniRef50_Q9RZL7 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Deinococcus|Rep: Ribonucleoside-diphosphate reductase -
           Deinococcus radiodurans
          Length = 702

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 29/75 (38%), Positives = 47/75 (62%)
 Frame = +1

Query: 19  WGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGT 198
           W KE+++L +      +   +V A+ L + I   Q E+G PY+LF+ + NR +   N+GT
Sbjct: 319 WTKEYQALADNPNIRKK---RVSARRLLEDIAVTQGESGYPYLLFEGNANRANPIPNVGT 375

Query: 199 IKCSNLCTEIVEYTS 243
           IK SNLC+EI++ T+
Sbjct: 376 IKMSNLCSEILQPTT 390



 Score = 39.9 bits (89), Expect = 0.058
 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKII-DVNYYPVPEAKKSNLRHRPIG 437
           CNLAS+ +       +T +   L  V       L+ +    + + VP  K++N   R IG
Sbjct: 411 CNLASLVIE------QTMHGGDLGRVVGAAIRMLDNVARSTSVHEVPAVKRANDEMRSIG 464

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           +G  GL        L Y SPEA+  ++ +       A +AS E+A
Sbjct: 465 LGAMGLHSFLAGKELIYGSPEALEFVDVFFAAVHYHARKASMEIA 509


>UniRef50_Q21U31 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Rhodoferax ferrireducens T118|Rep:
           Ribonucleoside-diphosphate reductase - Rhodoferax
           ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118)
          Length = 589

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 4/108 (3%)
 Frame = +3

Query: 261 CNLASIALNMFVDD----NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           CNL SI L+ FV      + + +   L+ V    T  L+ + D++ +P+   +KS L  R
Sbjct: 306 CNLGSINLSRFVQQPFAAHPSVDLGGLRAVAAVATRFLDDVYDISLFPLKAQQKSALASR 365

Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            IG+GV GLAD   ++ L Y S  +I+   + +      A   S ELA
Sbjct: 366 RIGLGVTGLADMLAMLGLRYGSAASIDLTREIMGAIRDTAYRTSVELA 413



 Score = 33.5 bits (73), Expect = 5.0
 Identities = 14/34 (41%), Positives = 23/34 (67%)
 Frame = +1

Query: 79  QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           +V A+ LW+ +++AQ  +G P +LF D  NR +N
Sbjct: 249 RVPARALWEKLLQAQHASGEPGVLFIDRINRANN 282


>UniRef50_A7IYE5 Cluster: Putivate ribonucleotide reductase; n=1;
           Corynebacterium phage P1201|Rep: Putivate ribonucleotide
           reductase - Corynebacterium phage P1201
          Length = 865

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 25/61 (40%), Positives = 40/61 (65%), Gaps = 1/61 (1%)
 Frame = +1

Query: 40  LYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNL 216
           +Y+T+ K++R     + A+ L++ I E Q E+G PY++F D+ NR +   N+G IK SNL
Sbjct: 320 MYDTWLKDDRIAKTFIDARKLFQTIAEVQFESGYPYLMFDDAANRGNPAPNIGRIKSSNL 379

Query: 217 C 219
           C
Sbjct: 380 C 380


>UniRef50_Q89YE5 Cluster: Ribonucleoside-diphosphate reductase;
           n=49; root|Rep: Ribonucleoside-diphosphate reductase -
           Bradyrhizobium japonicum
          Length = 723

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 28/67 (41%), Positives = 42/67 (62%), Gaps = 3/67 (4%)
 Frame = +1

Query: 58  KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNR--KSNQKNLG-TIKCSNLCTEI 228
           K N  V ++ A+ LW+ I+E +++TG PY+LF D+ NR    +Q+ LG  +  SNLC+EI
Sbjct: 345 KTNEVVREIDARQLWQRILENRLQTGEPYLLFIDTVNRALPKHQRELGLEVSTSNLCSEI 404

Query: 229 VEYTSDD 249
              T  D
Sbjct: 405 TLSTGID 411


>UniRef50_Q2LW62 Cluster: Ribonucleoside-diphosphate reductase alpha
           chain; n=1; Syntrophus aciditrophicus SB|Rep:
           Ribonucleoside-diphosphate reductase alpha chain -
           Syntrophus aciditrophicus (strain SB)
          Length = 551

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 33/106 (31%), Positives = 57/106 (53%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           C L SI L+  V  N   ++++L+++T      L+ +++V+ YP  E +     +R IG+
Sbjct: 285 CCLGSINLSRIVR-NGGIDWQRLQKLTHLGVRFLDDVVEVSTYPSEEIRAMTSGNRKIGL 343

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
           GV G A   I + +PY+SP+A     + ++L    +  AS  LA K
Sbjct: 344 GVMGFAHLLIRLGIPYDSPDAERTGGEIIRLIERESKIASNRLAEK 389



 Score = 34.3 bits (75), Expect = 2.9
 Identities = 17/49 (34%), Positives = 29/49 (59%)
 Frame = +1

Query: 79  QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           +V A+ L + I EA   +G P ++F D+ NR +   ++G I+ +N C E
Sbjct: 228 KVNARELLRFIAEAAWASGEPGVIFLDAINRANPTPHVGEIEATNPCGE 276


>UniRef50_Q18BC3 Cluster: Putative ribonucleotide-diphosphate
           reductase; n=2; Clostridium difficile|Rep: Putative
           ribonucleotide-diphosphate reductase - Clostridium
           difficile (strain 630)
          Length = 729

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 6/88 (6%)
 Frame = +3

Query: 261 CNLASIALNMFV----DDNKTYNFKKLKEVTKTITENLNKIID--VNYYPVPEAKKSNLR 422
           C L SI L+ F+     ++ T++  KLK   +     LN ++D  +N +P+ E + S  +
Sbjct: 364 CLLGSINLSEFIIQPFGEHATFDINKLKSCVREAVVALNDVLDEGLNLHPLQEQRDSVHK 423

Query: 423 HRPIGIGVQGLADAFILMRLPYESPEAI 506
           +R IG+GV G+AD  I M + Y S E++
Sbjct: 424 YRQIGLGVMGIADMLIKMGIRYGSDESL 451


>UniRef50_Q01037 Cluster: Ribonucleoside-diphosphate reductase large
           chain; n=12; Herpesviridae|Rep:
           Ribonucleoside-diphosphate reductase large chain -
           Saimiriine herpesvirus 2 (strain 11) (SaHV-2)
           (Herpesvirus saimiri)
          Length = 767

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180
           P L   +G EFE  Y     E ++   V  + L  ++I   ++TG+PY++ K++ N+   
Sbjct: 321 PNLTRLYGLEFEEEYLRLVSEKKYKQSVTLKSLMFSLINTIIKTGSPYVISKEAMNKHHW 380

Query: 181 QKNLG-TIKCSNLCTEIVE 234
            +  G  I CSNLC EIV+
Sbjct: 381 YETQGEAINCSNLCAEIVQ 399


>UniRef50_A3EPA5 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Leptospirillum sp. Group II UBA|Rep:
           Ribonucleoside-diphosphate reductase - Leptospirillum
           sp. Group II UBA
          Length = 732

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 31/108 (28%), Positives = 50/108 (46%), Gaps = 4/108 (3%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           CNL SI L   V  + T     ++++L          L+ ++D N +P+PE    N   R
Sbjct: 285 CNLGSINLERHVRSSATGKPEVDWERLGRSVYLAVRFLDNVVDANRFPIPELAAVNQGTR 344

Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            IG+G+ G A   + + +PY+S E +    K +      A   S +LA
Sbjct: 345 RIGLGIMGFARLLMRLEIPYDSEEGLEMAEKVMSFIRDEAERTSQDLA 392


>UniRef50_A2PYM5 Cluster: Ribonucleoside-diphosphate reductase alpha
           subunit; n=4; Cyanophage Ma|Rep:
           Ribonucleoside-diphosphate reductase alpha subunit -
           Cyanophage Ma-LMM02
          Length = 742

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 31/80 (38%), Positives = 43/80 (53%), Gaps = 7/80 (8%)
 Frame = +1

Query: 7   LADCWGKEFESLY---ETYEKENR----FVXQVRAQVLWKAIIEAQVETGTPYMLFKDSC 165
           LAD +G EF + Y   E Y   +      V +V A+ +WK ++   +ETGTPY+ FKD  
Sbjct: 365 LADMYGDEFTNAYHVIEAYINSSAPPLDVVKKVSAKAIWKKMLMLLLETGTPYVAFKDRI 424

Query: 166 NRKSNQKNLGTIKCSNLCTE 225
           N  +  K+ G I   NLC E
Sbjct: 425 NALNPNKHEGIIGGVNLCVE 444



 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 35/107 (32%), Positives = 51/107 (47%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           S  C L S+ L    DD       ++ +V++T    L+   D+   P PEA+    R+R 
Sbjct: 454 SHCCMLLSLVLPRIADD-------EMADVSRTAVRLLDAACDLTTSPTPEARAHVNRYRT 506

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           IG+GV GLAD   +  L Y+    +N I K  +       +AS ELA
Sbjct: 507 IGVGVMGLADWLAIRHLRYQD---LNLIEKLFEDICFYTTQASVELA 550


>UniRef50_O36411 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Alcelaphine herpesvirus 1|Rep:
           Ribonucleoside-diphosphate reductase - Alcelaphine
           herpesvirus 1 (wildebeest herpesvirus)
          Length = 780

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 2/83 (2%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186
           LA+ +G EF S YE       +   +  + L   II   ++TG+PY+++K++CN + + K
Sbjct: 324 LANLYGDEFRSEYERLVGIGCYADAIPIKSLMFLIINTIIKTGSPYIIYKEACN-EHHWK 382

Query: 187 NLG--TIKCSNLCTEIVEYTSDD 249
           N+    I  +NLC E+++Y   D
Sbjct: 383 NMEGCAIASANLCAEVIQYPGAD 405


>UniRef50_A3W1N9 Cluster: Ribonucleoside-diphosphate reductase; n=8;
            Bacteria|Rep: Ribonucleoside-diphosphate reductase -
            Roseovarius sp. 217
          Length = 1131

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 33/121 (27%), Positives = 56/121 (46%)
 Frame = +3

Query: 264  NLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIG 443
            NLA +    F    +  +   L ++ +     ++ ++DV+ +P+P         R IG+G
Sbjct: 655  NLARLVTEPFATGARV-DAAALDDLVRVAVRMMDNVVDVSGFPLPAQAAEAQAKRRIGLG 713

Query: 444  VQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAPASR 623
            V GLADA +++ L Y S EA+     +L      A  AS +LA +     +   DA  + 
Sbjct: 714  VTGLADALLMVGLRYGSDEAVQQTEAWLHAIARAAYLASVDLAREKGAFPLFDRDAYLAS 773

Query: 624  G 626
            G
Sbjct: 774  G 774



 Score = 34.3 bits (75), Expect = 2.9
 Identities = 18/62 (29%), Positives = 28/62 (45%)
 Frame = +1

Query: 67  RFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVEYTSD 246
           R    V+A+ LW  I++A  +   P ++F D  N  +N     TI  +N C     +   
Sbjct: 216 RVYHTVQARDLWNRIMQATYDYAEPGVIFIDRINAANNLSYCETIAATNPCVTAETWVMT 275

Query: 247 DE 252
           DE
Sbjct: 276 DE 277


>UniRef50_A0MN59 Cluster: Ribonucleotide reductase alpha subunit;
           n=1; Thermus phage phiYS40|Rep: Ribonucleotide reductase
           alpha subunit - Thermus phage phiYS40
          Length = 797

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 31/112 (27%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
 Frame = +3

Query: 261 CNLASIALNMFVDD--------NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSN 416
           CNL SI L+ FV +         + ++F KL EV++ +   L+ + D+   P+ + K++ 
Sbjct: 452 CNLGSIFLHRFVKEPFNYDLKPEENFDFDKLFEVSRLMNRFLDFVNDITNLPLVQLKEAA 511

Query: 417 LRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
              R  G+G+ G+AD  I++ L Y S EA   + K +    + +   +  +A
Sbjct: 512 FTKRRHGLGISGIADTLIMVGLRYGSEEAAKFLEKIMYTIQLASAVENVRMA 563


>UniRef50_P50643 Cluster: Ribonucleoside-diphosphate reductase large
           chain; n=18; Herpesviridae|Rep:
           Ribonucleoside-diphosphate reductase large chain -
           Pseudorabies virus (strain Kaplan) (PRV)
          Length = 835

 Score = 52.8 bits (121), Expect = 8e-06
 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186
           LA   G +F   YE  E+    V  +  Q +   I+ + V TG+P+++ KD+CNR  +  
Sbjct: 420 LASLHGPDFAREYERLERLGLGVESLPIQDMAFLIVRSAVMTGSPFLMMKDACNRHFHTD 479

Query: 187 NLG-TIKCSNLCTEIVEYTSDDE 252
             G  +  SNLCTEIV+  +  E
Sbjct: 480 TRGAALATSNLCTEIVQRATPGE 502



 Score = 43.6 bits (98), Expect = 0.005
 Identities = 27/109 (24%), Positives = 49/109 (44%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           + VCNLAS+ L   +     ++F  L+   +     +N ++ +  YP   + +   R R 
Sbjct: 503 NGVCNLASVNLPACLAGG-AFDFAALRRAARVAAVFVNAMMRIGNYPTGASVEGVRRSRS 561

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
           +GIG+QGL    + + +    P A        +    G ++AS EL  +
Sbjct: 562 LGIGLQGLHTTVLALDMDMADPAARRLNAAIAEELLYGVMDASVELCER 610


>UniRef50_Q7NEB4 Cluster: Gll3966 protein; n=1; Gloeobacter
            violaceus|Rep: Gll3966 protein - Gloeobacter violaceus
          Length = 1566

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 5/120 (4%)
 Frame = +3

Query: 252  SAVCNLASIALNMFVDDNKT---YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422
            ++ CNL SI ++ F+   +     +++ L    +  T  L+ ++DV  +  P A+K N+R
Sbjct: 1131 NSACNLGSIVISKFMHRTERGVELDWEDLARTVEISTRFLDNVLDVAEFATP-AQKHNVR 1189

Query: 423  H--RPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMI 596
            +  R +G+G+ G AD     R+PY+S   +  I+K  +     A   S  LAA+   C I
Sbjct: 1190 NVFRQLGLGIMGWADWLKARRIPYDSEAHLREIDKVGRFIAERAYRTSEALAAEKGACGI 1249


>UniRef50_A3I5A9 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Bacillus sp. B14905|Rep: Ribonucleoside-diphosphate
           reductase - Bacillus sp. B14905
          Length = 697

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 41/68 (60%), Gaps = 1/68 (1%)
 Frame = +1

Query: 34  ESLYETYEKEN-RFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCS 210
           E  YE  +    R + ++ A+ L+  + +AQ E+G P+ +F D+ N     KN+G +K S
Sbjct: 317 EMYYELLDNPKIRKIKRLNARRLYTEVKKAQFESGYPFEIFDDNVNEVHPLKNIGRVKMS 376

Query: 211 NLCTEIVE 234
           NLCTEI++
Sbjct: 377 NLCTEILQ 384



 Score = 38.7 bits (86), Expect = 0.13
 Identities = 26/122 (21%), Positives = 59/122 (48%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL SI ++     +K  +F+ L +    +  N++++  +    VP   K+N     +G+
Sbjct: 406 CNLGSIDIHAA---SKVNDFETLIDTAMHLLTNVSQMTYIKN--VPSVAKANRLMHSVGL 460

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAPAS 620
           G   L    +   + Y S ++I+ ++++++     +L++S E+A +  E      D+  +
Sbjct: 461 GCMNLHGHLVTEGIMYGSKDSIDFMDRFMEAMNYYSLKSSMEMAKEKAETFYRFEDSDYA 520

Query: 621 RG 626
            G
Sbjct: 521 SG 522


>UniRef50_Q7UI46 Cluster: Vitamin B12-dependent ribonucleotide
           reductase; n=3; Bacteria|Rep: Vitamin B12-dependent
           ribonucleotide reductase - Rhodopirellula baltica
          Length = 1040

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 30/107 (28%), Positives = 49/107 (45%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNLASI L  FV  + +++ ++ +   +T       ++D   YP     +++ + RP+G+
Sbjct: 433 CNLASINLMKFVQQDGSFDHERFRAACRTFFIAQEILVDHASYPTEPIARNSHKFRPLGL 492

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKV 581
           G   L    +   LPY+S  A         L    A   S ELA+ V
Sbjct: 493 GYSNLGSVIMTAGLPYDSDAARGMCGSLTALLHGEANRTSAELASVV 539


>UniRef50_A4IY36 Cluster: Ribonucleoside-diphosphate reductase,
           alpha chain; n=18; root|Rep: Ribonucleoside-diphosphate
           reductase, alpha chain - Francisella tularensis subsp.
           tularensis (strain WY96-3418)
          Length = 590

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 25/52 (48%), Positives = 36/52 (69%), Gaps = 3/52 (5%)
 Frame = +1

Query: 82  VRAQVLWKAIIEAQVETGTPYMLFKDSCNR--KSNQKNLG-TIKCSNLCTEI 228
           ++A+ +W+ I+E +  TG PY+ F D+ NR    +QK+LG TIK SNLC EI
Sbjct: 229 IKARKIWETILETRYRTGEPYLNFIDTANRALPKSQKDLGLTIKGSNLCNEI 280



 Score = 39.5 bits (88), Expect = 0.076
 Identities = 32/112 (28%), Positives = 53/112 (47%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           +AVC L+S+ L  + D+ K  +   +K++ + +   L   ID     + +A+ S  R R 
Sbjct: 289 TAVCCLSSVNLERY-DEWKDTSL--IKDLIRFLDNVLQFFIDHAGDEISKARYSASRERS 345

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWE 587
           +G+G  G      L R+P+ES  A     +  K     ALE +  L A+  E
Sbjct: 346 LGLGAMGFHSYLQLHRVPFESQRAKEINEEIFKRIKEQALEETLILGAEKGE 397


>UniRef50_Q1FPU1 Cluster: Ribonucleoside-diphosphate reductase; n=4;
           Clostridium|Rep: Ribonucleoside-diphosphate reductase -
           Clostridium phytofermentans ISDg
          Length = 764

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 38/59 (64%)
 Frame = +1

Query: 82  VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVEYTSDDEVQ 258
           V A  + K I+++ VETG P++ F+D+ N+ +  K+ G I  SNLC EI +  S+ E++
Sbjct: 413 VPALEVMKRIMKSAVETGAPFIFFRDTVNQANPNKHAGMIYSSNLCQEITQNMSESELR 471


>UniRef50_Q8Y2Y6 Cluster: Ribonucleoside-diphosphate reductase;
           n=12; Burkholderiaceae|Rep: Ribonucleoside-diphosphate
           reductase - Ralstonia solanacearum (Pseudomonas
           solanacearum)
          Length = 617

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 30/90 (33%), Positives = 45/90 (50%)
 Frame = +3

Query: 360 LNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFT 539
           L+  ID+  +P+ E  +     R IG+GV GLADA  +M LPY++PEA N   +  +   
Sbjct: 355 LDNAIDITRWPLIEHMREAHAKRRIGVGVTGLADALTMMGLPYQAPEARNLAVQIGRCLR 414

Query: 540 MGALEASCELAAKVWECMIHTTDAPASRGH 629
             A  AS  LA +     +   +   + GH
Sbjct: 415 DNAYAASAALAQERSPYPLFRAERSLAPGH 444



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 17/48 (35%), Positives = 26/48 (54%)
 Frame = +1

Query: 82  VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           V A+ LW  ++EA   +  P +LF D+ N  ++   L TI  +N C E
Sbjct: 260 VPARQLWDMLVEAAHHSAEPGLLFIDTINAANDLAELETIAATNPCGE 307


>UniRef50_A1HDY4 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Ralstonia pickettii 12J|Rep: Ribonucleoside-diphosphate
           reductase - Ralstonia pickettii 12J
          Length = 596

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 30/108 (27%), Positives = 50/108 (46%)
 Frame = +3

Query: 312 YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYE 491
           ++F  L    +     L+  I++  +P+PE        R IG+GV GLADA  +M LPY+
Sbjct: 327 FDFVGLSRAVRVQVRMLDNAIEITRWPLPEHMHEAQAKRRIGVGVTGLADALTMMCLPYD 386

Query: 492 SPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAPASRGHIT 635
           +P A     +  +     A  AS  LA +     + + +   + GH +
Sbjct: 387 APAARCFAAQIGRCLRDSAYAASAALACERGPYPLFSPERSLAPGHFS 434



 Score = 33.5 bits (73), Expect = 5.0
 Identities = 17/48 (35%), Positives = 25/48 (52%)
 Frame = +1

Query: 82  VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           V A+ LW  I EA   +  P +LF D+ N  ++   + TI  +N C E
Sbjct: 248 VPARQLWNMIAEAAHHSAEPGLLFIDTINAANDLAEIETIAATNPCGE 295


>UniRef50_Q3B5C1 Cluster: Ribonucleotide reductase family protein;
            n=3; Chlorobium/Pelodictyon group|Rep: Ribonucleotide
            reductase family protein - Pelodictyon luteolum (strain
            DSM 273) (Chlorobium luteolum (strain DSM273))
          Length = 1521

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 27/108 (25%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
 Frame = +3

Query: 252  SAVCNLASIALNMFVDDNKTY-NFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
            +  CNLAS+ L  FVD+   +    +L+      T  L   + + ++P P+  + +  +R
Sbjct: 832  NTACNLASLNLIHFVDEESGHVKINELRHAAALWTVVLEISVLMAHFPSPDIARLSYEYR 891

Query: 429  PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
             +G+G   L    +++ +PY+SP+A+        + T  A   S E++
Sbjct: 892  TLGLGFANLGTVLMVLGIPYDSPKALALAGAISAIITGQAYVTSAEIS 939


>UniRef50_Q3SMN2 Cluster: Ribonucleoside-diphosphate reductase alpha
           chain; n=1; Thiobacillus denitrificans ATCC 25259|Rep:
           Ribonucleoside-diphosphate reductase alpha chain -
           Thiobacillus denitrificans (strain ATCC 25259)
          Length = 600

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 33/109 (30%), Positives = 56/109 (51%), Gaps = 5/109 (4%)
 Frame = +3

Query: 261 CNLASIALNMFV----DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVP-EAKKSNLRH 425
           C+L S+ L  FV      +   +   L +        L+ +IDV+ YP+  +A+++  + 
Sbjct: 301 CDLGSLNLTAFVVAPFAADARLDLAALGDAAALAVRFLDDVIDVSRYPLQAQAREARFKR 360

Query: 426 RPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           R IG+G+ GLADA +L+ L Y+S  A     + ++     A  AS +LA
Sbjct: 361 R-IGLGITGLADALVLLGLDYDSEPARQLAERAMRTVRDAAYRASIDLA 408



 Score = 41.9 bits (94), Expect = 0.014
 Identities = 20/54 (37%), Positives = 30/54 (55%)
 Frame = +1

Query: 67  RFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEI 228
           R +  VRA+ LW+ I+ A  +T  P +LF D+ NR +      T+  +N C EI
Sbjct: 240 RVLRTVRARALWQRILRAAYDTAEPGVLFVDTINRDNTLAGRETLTTTNPCGEI 293


>UniRef50_Q1J1T0 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Deinococcus geothermalis DSM 11300|Rep:
           Ribonucleoside-diphosphate reductase - Deinococcus
           geothermalis (strain DSM 11300)
          Length = 1010

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 25/78 (32%), Positives = 45/78 (57%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           C+L +I L  +V  N  ++F   +   +T    L+ ++DVN + + + + ++   R +G+
Sbjct: 481 CDLGAINLAAYVQ-NSRFDFAAFRADVRTCVRFLDDVLDVNVFALEDNRVASQDLRRLGL 539

Query: 441 GVQGLADAFILMRLPYES 494
           GV GLADA I + L Y+S
Sbjct: 540 GVMGLADALIKLGLRYDS 557



 Score = 35.9 bits (79), Expect = 0.94
 Identities = 22/52 (42%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
 Frame = +1

Query: 82  VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLG---TIKCSNLCTEI 228
           V A+ LW  I E    TG P ++F D  N  S  KNLG    I+ +N C EI
Sbjct: 422 VPAKWLWDQIAEHAWATGEPGLIFVDRVNEHSALKNLGKRYEIRSTNPCGEI 473


>UniRef50_Q120H3 Cluster: Ribonucleotide reductase large subunit;
           n=1; Polaromonas sp. JS666|Rep: Ribonucleotide reductase
           large subunit - Polaromonas sp. (strain JS666 / ATCC
           BAA-500)
          Length = 784

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 4/108 (3%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           C L S  L  FV +  T    ++F  L +V     E L+K++D  ++P+P+        R
Sbjct: 334 CCLGSPNLTRFVSNPFTLMASFDFDGLSKVVAKAVEMLDKVLDKTHWPLPQQASEAANKR 393

Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            IG+G  GLADA  ++ + Y+S +  +      ++    A  AS  LA
Sbjct: 394 RIGLGHFGLADAMAMLGIRYDSQQGADFAAHVSEVLRDSAYMASVNLA 441


>UniRef50_Q0LX20 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Alphaproteobacteria|Rep: Ribonucleoside-diphosphate
           reductase - Caulobacter sp. K31
          Length = 782

 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 31/105 (29%), Positives = 50/105 (47%)
 Frame = +3

Query: 264 NLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIG 443
           NLA +  N F  D    +  +L  + +T    L+ +ID++ +P+          R +GIG
Sbjct: 323 NLARLVDNPFEAD-AALDEDRLGALARTAVRMLDNVIDISRFPLEAQAVEARAKRRLGIG 381

Query: 444 VQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
           V GLADA +     Y   +A+    ++L +    A  AS  LAA+
Sbjct: 382 VTGLADALVFCGARYGDDQAVALTQRWLGVIKREAYRASARLAAE 426


>UniRef50_O55716 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Invertebrate iridescent virus 6|Rep:
           Ribonucleoside-diphosphate reductase - Chilo iridescent
           virus (CIV) (Insect iridescent virus type 6)
          Length = 959

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 3/69 (4%)
 Frame = +1

Query: 22  GKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRK--SNQKNLG 195
           G   +  +   +   + +  V A+ LW+ I+E +++TG PY+ F D+CN+     QK  G
Sbjct: 204 GGNIDDTWNLIDPHTKKITTVGARDLWQRILETRMKTGEPYICFIDTCNKHMYDFQKKKG 263

Query: 196 -TIKCSNLC 219
            TIK SNLC
Sbjct: 264 LTIKQSNLC 272


>UniRef50_Q6MNP6 Cluster: Vitamin B12-dependent ribonucleotide
           reductase; n=1; Bdellovibrio bacteriovorus|Rep: Vitamin
           B12-dependent ribonucleotide reductase - Bdellovibrio
           bacteriovorus
          Length = 764

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 22/82 (26%), Positives = 42/82 (51%)
 Frame = +3

Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
           + CNLASI L  F++D   ++F+      +T+      ++D + YP     +++  +RP+
Sbjct: 387 SACNLASINLVKFLNDTGDFDFESFIHTARTLFVAQEILVDYSSYPTQRVAQNSHDYRPL 446

Query: 435 GIGVQGLADAFILMRLPYESPE 500
           G+G   L    +   + Y+S E
Sbjct: 447 GLGFANLGSLLMRKGVAYDSDE 468


>UniRef50_Q88YQ4 Cluster: Ribonucleoside-diphosphate reductase,
           alpha chain; n=57; Lactobacillales|Rep:
           Ribonucleoside-diphosphate reductase, alpha chain -
           Lactobacillus plantarum
          Length = 721

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 37/145 (25%), Positives = 65/145 (44%), Gaps = 1/145 (0%)
 Frame = +3

Query: 261 CNLASIAL-NMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437
           CNL S  + N+    +  ++ + +      +T++ N  +DV    VP  +K N +   IG
Sbjct: 409 CNLGSTNIVNLMTSPDFGHSVEAMVRALTFVTDHSN--VDV----VPSIQKGNRQAHTIG 462

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAPA 617
           +G  GL   F   ++ Y S EA++  N Y  L     L+AS E+A +  E  ++   +  
Sbjct: 463 LGAMGLHAFFAKNQMEYGSKEAVDFTNIYFLLLNYWTLKASNEIARERHETFVNFEKSKY 522

Query: 618 SRGHITVRHVELKIQPGFMGTGTCF 692
           + G    ++     QP +  T   F
Sbjct: 523 ADGSYFDKYTTQDWQPKYDKTAALF 547



 Score = 36.7 bits (81), Expect = 0.54
 Identities = 22/65 (33%), Positives = 39/65 (60%), Gaps = 4/65 (6%)
 Frame = +1

Query: 79  QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVEYTS----D 246
           +++A+ L   I + Q E+G PY++  D+ NR++     G I  SNLC+E+++  +    D
Sbjct: 338 KIKARDLENEISKLQQESGYPYVVNIDTANRENPID--GKIVMSNLCSEVMQVQTPSLID 395

Query: 247 DEVQY 261
           D+ QY
Sbjct: 396 DQQQY 400


>UniRef50_A5JBG3 Cluster: Ribonucleotide reductase, large subunit;
           n=11; Burkholderia|Rep: Ribonucleotide reductase, large
           subunit - Burkholderia mallei FMH
          Length = 677

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 28/89 (31%), Positives = 42/89 (47%)
 Frame = +3

Query: 312 YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYE 491
           ++F       +     L+  +DV  +P+    + + + R IG+GV GLAD   +MRL Y+
Sbjct: 407 FDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYD 466

Query: 492 SPEAIN*INKYLKLFTMGALEASCELAAK 578
           SP A              A  AS ELAA+
Sbjct: 467 SPAAREMARYIASDLRHHAYAASAELAAE 495


>UniRef50_UPI00004BA6C5 Cluster: UPI00004BA6C5 related cluster; n=1;
           unknown|Rep: UPI00004BA6C5 UniRef100 entry - unknown
          Length = 969

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 20/55 (36%), Positives = 33/55 (60%)
 Frame = +1

Query: 55  EKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219
           E EN    ++ A+ +   I + Q+++G PY+++KD+ N+      LG IK SNLC
Sbjct: 324 ENENVIKHKINAREMLNLIAQIQLQSGYPYIMYKDNANKNHALNELGEIKMSNLC 378



 Score = 38.7 bits (86), Expect = 0.13
 Identities = 28/108 (25%), Positives = 54/108 (50%), Gaps = 1/108 (0%)
 Frame = +3

Query: 258  VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYP-VPEAKKSNLRHRPI 434
            +CNLAS  LNM     K+   K+++E  +T    L  + + +    +P   K+N  +R +
Sbjct: 788  ICNLAS--LNMV----KSIEEKEIEESIRTGMRALTFVANNSRIEHLPTVHKANKNNRAV 841

Query: 435  GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578
            G+GV          ++ Y S E+++ +N Y  +    +L+ S ++A +
Sbjct: 842  GLGVMSFHSMCAKNKIRYGSEESLDLLNVYCMMMDYYSLDESMKIAVE 889


>UniRef50_Q196Z5 Cluster: Ribonucleoside-diphosphate reductase; n=1;
           Aedes taeniorhynchus iridescent virus|Rep:
           Ribonucleoside-diphosphate reductase - Aedes
           taeniorhynchus iridescent virus
          Length = 630

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 26/58 (44%), Positives = 38/58 (65%), Gaps = 3/58 (5%)
 Frame = +1

Query: 82  VRAQVLWKAIIEAQVETGTPYMLFKDSCNR--KSNQKNLG-TIKCSNLCTEIVEYTSD 246
           ++A  LW+ II  + ETG PY+ + D+ NR     QKNLG +I+ SNLC+E+V  T +
Sbjct: 271 IKATELWERIILTRAETGEPYIHWIDTSNRALPQFQKNLGLSIRQSNLCSEVVLPTDE 328


>UniRef50_A4WLF4 Cluster: Ribonucleoside-diphosphate reductase,
            adenosylcobalamin-dependent; n=1; Pyrobaculum arsenaticum
            DSM 13514|Rep: Ribonucleoside-diphosphate reductase,
            adenosylcobalamin-dependent - Pyrobaculum arsenaticum
            (strain DSM 13514 / JCM 11321)
          Length = 1240

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 10/115 (8%)
 Frame = +3

Query: 258  VCNLASIALNMFVDDN----------KTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAK 407
            VCNL  I L  FV DN             ++  L +  +  T  L+  ID +   +    
Sbjct: 842  VCNLTHINLVKFVKDNCGGGSFEEKLGCIDWDGLAQAARVGTRFLDDAIDRSKTGIEVID 901

Query: 408  KSNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            + N   R  G+G+ G A+  I + +PY S EA+  IN+ +    + AL+ S ELA
Sbjct: 902  EMNAATRKNGLGIMGFAELLIKLGVPYASWEAVELINRIMGWIYVNALDESAELA 956


>UniRef50_Q9RRW1 Cluster: Ribonucleoside-diphosphate reductase; n=1;
            Deinococcus radiodurans|Rep: Ribonucleoside-diphosphate
            reductase - Deinococcus radiodurans
          Length = 1418

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 24/78 (30%), Positives = 45/78 (57%)
 Frame = +3

Query: 261  CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
            C+L +I L  +V  +  ++F   +   +T    L+ ++DVN + + + + ++   R +G+
Sbjct: 902  CDLGAINLAAYVRGSD-FDFAAFRADVRTCVRFLDDVLDVNVFALEDNRVASQDLRRLGL 960

Query: 441  GVQGLADAFILMRLPYES 494
            GV GLADA I M L Y++
Sbjct: 961  GVMGLADALIKMGLRYDN 978


>UniRef50_Q604J6 Cluster: Ribonucleoside-diphosphate reductase; n=3;
           Proteobacteria|Rep: Ribonucleoside-diphosphate reductase
           - Methylococcus capsulatus
          Length = 1317

 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           C L S+ L  FV    T    +  ++L EV       L+ ++D  Y+P+   ++     R
Sbjct: 674 CCLGSLDLTRFVSRPFTPEAAFEAERLAEVATIAVRMLDNVLDTTYWPLARQRQEAQAKR 733

Query: 429 PIGIGVQGLADAFILMRLPYESPEA 503
            IG+G  GL DA  ++ L Y+S  A
Sbjct: 734 RIGLGFTGLGDALAMLGLRYDSAAA 758


>UniRef50_Q8ZTP7 Cluster: Ribonucleoside-diphosphate reductase; n=3;
           Pyrobaculum|Rep: Ribonucleoside-diphosphate reductase -
           Pyrobaculum aerophilum
          Length = 849

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 10/115 (8%)
 Frame = +3

Query: 258 VCNLASIALNMFVDDNKT----------YNFKKLKEVTKTITENLNKIIDVNYYPVPEAK 407
           VCNL  I L  FV +N             +++ L +  +  T  L+  I+ +   +    
Sbjct: 451 VCNLTHINLVKFVKENCAGGSFEEKLGCIDWEGLAQAARVGTRYLDDAIERSRTGIKIID 510

Query: 408 KSNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           + N   R  G+G+ G A+  I + +PY S EA+  IN+ +    + AL+ S ELA
Sbjct: 511 EMNSATRKNGLGIMGFAELLIKLGIPYASWEAVELINRIMGWIYVNALDESAELA 565


>UniRef50_P78027 Cluster: Ribonucleoside-diphosphate reductase
           subunit alpha; n=36; Firmicutes|Rep:
           Ribonucleoside-diphosphate reductase subunit alpha -
           Mycoplasma pneumoniae
          Length = 721

 Score = 45.2 bits (102), Expect = 0.002
 Identities = 24/76 (31%), Positives = 40/76 (52%)
 Frame = +1

Query: 34  ESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSN 213
           E  YE    +      + A+  ++ + E   E+G PY+LF D+ NR++   N   I  SN
Sbjct: 327 EMYYELLANQRIKKTFINARKFFQTVAELHFESGYPYILFDDTVNRRNAHPN--RIVMSN 384

Query: 214 LCTEIVEYTSDDEVQY 261
           LC+EIV+ ++  E  +
Sbjct: 385 LCSEIVQPSTPSEFHH 400



 Score = 42.3 bits (95), Expect = 0.011
 Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDV-NYYPVPEAKKSNLRHRPIG 437
           CNL S+ +   ++    ++     E+ K   E+L+ +  V N    P  +K N  +  +G
Sbjct: 413 CNLGSLNIAKAMESGPEFS-----ELVKLAIESLDLVSRVSNLETAPSIQKGNSENHALG 467

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           +G   L       ++ Y SPEAI+  N +       A +AS ELA
Sbjct: 468 LGAMNLHGFLATNQIYYNSPEAIDFTNIFFYTVAYHAFKASSELA 512


>UniRef50_A7CVZ3 Cluster: Ribonucleoside-diphosphate reductase
           precursor; n=1; Opitutaceae bacterium TAV2|Rep:
           Ribonucleoside-diphosphate reductase precursor -
           Opitutaceae bacterium TAV2
          Length = 613

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 4/69 (5%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEK---ENRFVX-QVRAQVLWKAIIEAQVETGTPYMLFKDSCN 168
           P L + +G++FE  Y  YE    E +    ++ A  LWK ++    ETG  ++ FKD+CN
Sbjct: 544 PDLHELYGRKFEDAYLRYETLAAEGKIHGHRIAALDLWKKMLSMLFETGHTWLTFKDACN 603

Query: 169 RKSNQKNLG 195
            +S Q + G
Sbjct: 604 IRSPQDHAG 612


>UniRef50_A1W357 Cluster: Ribonucleoside-diphosphate reductase;
           n=16; Burkholderiales|Rep: Ribonucleoside-diphosphate
           reductase - Acidovorax sp. (strain JS42)
          Length = 811

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 6/110 (5%)
 Frame = +3

Query: 261 CNLASIALNMFVDD------NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422
           C+L  I L  FV +        +++F   ++   T    L+ ++DV ++P+P+ +  +  
Sbjct: 308 CDLGPIILTRFVRNPFGLHGEASFDFDAFEQAVATQVRALDNVLDVTFWPLPQQQAESAA 367

Query: 423 HRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            R IG+G  G+ +   ++   Y+  E  +   +  +     A  AS ELA
Sbjct: 368 KRRIGVGFTGMGNTLAMLCKRYDRQEGRDMAVQIAERMRNAAYRASVELA 417



 Score = 35.1 bits (77), Expect = 1.6
 Identities = 17/48 (35%), Positives = 26/48 (54%)
 Frame = +1

Query: 82  VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           VRA+ LW  I+++  +   P +LF D  N  +N     TI+ +N C E
Sbjct: 252 VRARELWDTIMKSAYDFAEPGILFLDQINTDNNLHYTETIQATNPCGE 299


>UniRef50_A1TJY2 Cluster: Ribonucleoside-diphosphate reductase,
            adenosylcobalamin-dependent; n=3; Comamonadaceae|Rep:
            Ribonucleoside-diphosphate reductase,
            adenosylcobalamin-dependent - Acidovorax avenae subsp.
            citrulli (strain AAC00-1)
          Length = 1226

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 6/110 (5%)
 Frame = +3

Query: 261  CNLASIALNMFVDD------NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422
            C+L  I L  FV           ++F        T    L+ ++DV ++P+P+ +  +  
Sbjct: 701  CDLGPIILPRFVRHPFGFAGEPAFDFDAFAASVATQVRALDNVLDVTFWPLPQQRAESAA 760

Query: 423  HRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
             R IG+G  GL +   ++RL Y++        +  +     A  AS ELA
Sbjct: 761  KRRIGVGFTGLGNTLAMLRLRYDTDAGRAMAMRIAECMRDAAYAASVELA 810


>UniRef50_P0A5W9 Cluster: Ribonucleoside-diphosphate reductase
           subunit alpha; n=110; Bacteria|Rep:
           Ribonucleoside-diphosphate reductase subunit alpha -
           Mycobacterium bovis
          Length = 725

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 23/70 (32%), Positives = 43/70 (61%)
 Frame = +1

Query: 34  ESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSN 213
           E  YE  +       +++A+  ++ + E Q E+G PY++F+D+ NR +N  + G I  SN
Sbjct: 340 EKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNR-ANPID-GKITHSN 397

Query: 214 LCTEIVEYTS 243
           LC+EI++ ++
Sbjct: 398 LCSEILQVST 407


>UniRef50_Q2S5T5 Cluster: Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent; n=1; Salinibacter ruber DSM
           13855|Rep: Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent - Salinibacter ruber (strain
           DSM 13855)
          Length = 894

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
 Frame = +3

Query: 258 VCNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
           VC L ++ +   VD +  T ++  + ++       L+ + D++Y P+ E +++    R I
Sbjct: 373 VCLLGNLNVTQLVDREAGTIDYDLVDDLVPLAVRFLDNVNDLSYVPLEEQQRNLQEKRRI 432

Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           G+G  G   A ++M+  Y S E    + ++ +     A +AS  LA
Sbjct: 433 GLGHYGDGSALMMMKTRYGSEEGARVMREFQEHLANQAYQASARLA 478


>UniRef50_P03190 Cluster: Ribonucleoside-diphosphate reductase large
           chain; n=5; Lymphocryptovirus|Rep:
           Ribonucleoside-diphosphate reductase large chain -
           Epstein-Barr virus (strain B95-8) (HHV-4) (Human
           herpesvirus 4)
          Length = 826

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 21/73 (28%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
 Frame = +1

Query: 19  WGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLG- 195
           +G+EFE  Y       +F  +V  + L  +I+   V+ G+P++L K++CN    +   G 
Sbjct: 322 YGEEFEREYYRLVTAGKFCGRVSIKSLMFSIVNCAVKAGSPFILLKEACNAHFWRDLQGE 381

Query: 196 TIKCSNLCTEIVE 234
            +  +NLC E+++
Sbjct: 382 AMNAANLCAEVLQ 394


>UniRef50_Q9HPG8 Cluster: Ribonucleoside-diphosphate reductase; n=5;
           root|Rep: Ribonucleoside-diphosphate reductase -
           Halobacterium salinarium (Halobacterium halobium)
          Length = 1051

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 23/74 (31%), Positives = 39/74 (52%)
 Frame = +3

Query: 351 TENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLK 530
           T  L  ++ ++ +PVPE ++     R IG+GV GLA  +I + + Y S E     ++ ++
Sbjct: 499 TRFLENVVTMSDFPVPEIEQKVSEMRKIGLGVMGLAQLYIQLGVKYGSEEGNEIASQLMQ 558

Query: 531 LFTMGALEASCELA 572
                +  AS ELA
Sbjct: 559 TINHDSKTASHELA 572


>UniRef50_Q5DN91 Cluster: Ribonucleotide reductase; n=1; Phage
           phiJL001|Rep: Ribonucleotide reductase - Phage phiJL001
          Length = 602

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 24/92 (26%), Positives = 44/92 (47%)
 Frame = +3

Query: 297 DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILM 476
           D   T+++         +   ++ ++D   YP+ E +K     R +G+GV  LA+A   +
Sbjct: 319 DSRWTFDWDLFATDVYAVVRAMDNVVDRAIYPLFEQEKEAKSKRRMGLGVTALANAAEAL 378

Query: 477 RLPYESPEAIN*INKYLKLFTMGALEASCELA 572
            +PY S E +    + L+     + +AS ELA
Sbjct: 379 GMPYGSIEFLKFEGQVLETLACNSYQASVELA 410



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 17/48 (35%), Positives = 25/48 (52%)
 Frame = +1

Query: 82  VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           + A+ LW+ I+ +  +   P  LF D  NR +N K   TI  +N C E
Sbjct: 239 INAENLWEMIMRSTWDWAEPGTLFIDQINRMNNLKYCETIAATNPCGE 286


>UniRef50_Q2NME4 Cluster: Ribonucleoside-diphosphate reductase large
           chain; n=2; unclassified Iridovirus|Rep:
           Ribonucleoside-diphosphate reductase large chain -
           Costelytra zealandica iridescent virus (CzIV) (Insect
           iridescent virustype 16)
          Length = 378

 Score = 41.5 bits (93), Expect = 0.019
 Identities = 28/74 (37%), Positives = 40/74 (54%), Gaps = 4/74 (5%)
 Frame = +1

Query: 10  ADCWGKEFESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRK--SN 180
           A  + KE +  ++  +  N+ V + + A  LW+ I+  + E G PY  F D+ NRK    
Sbjct: 90  AQTYIKEMDK-FDLTDPHNKEVKETISATELWERILVTRAECGEPYCHFIDTSNRKLPEF 148

Query: 181 QKNLG-TIKCSNLC 219
           QK LG  IK SNLC
Sbjct: 149 QKKLGLNIKQSNLC 162


>UniRef50_P50620 Cluster: Ribonucleoside-diphosphate reductase
           subunit alpha; n=53; Bacteria|Rep:
           Ribonucleoside-diphosphate reductase subunit alpha -
           Bacillus subtilis
          Length = 700

 Score = 41.5 bits (93), Expect = 0.019
 Identities = 31/137 (22%), Positives = 64/137 (46%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440
           CNL S+ + + V ++K+   K +K  T ++T ++++  D+     P  +++N   + IG+
Sbjct: 409 CNLGSLNI-LNVMEHKSIE-KTVKLATDSLT-HVSETTDIRN--APAVRRANKAMKSIGL 463

Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAPAS 620
           G   L        + YESPEA +  N +  +    +++ S E+A +  E       +  +
Sbjct: 464 GAMNLHGYLAQNGIAYESPEARDFANTFFMMVNFYSIQRSAEIAKEKGETFDQYEGSTYA 523

Query: 621 RGHITVRHVELKIQPGF 671
            G    ++V     P +
Sbjct: 524 TGEYFDKYVSTDFSPKY 540



 Score = 39.5 bits (88), Expect = 0.076
 Identities = 16/70 (22%), Positives = 39/70 (55%), Gaps = 1/70 (1%)
 Frame = +1

Query: 28  EFESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIK 204
           +   +Y+ +    R   + +  + L + +   + E+G PY++F+D+ N+     ++  +K
Sbjct: 318 DMNEMYDKFVDNPRVKKEKINPRKLLEKLAMLRSESGYPYIMFQDNVNKVHANNHISKVK 377

Query: 205 CSNLCTEIVE 234
            SNLC+E+++
Sbjct: 378 FSNLCSEVLQ 387


>UniRef50_O41962 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Murid herpesvirus 4|Rep: Ribonucleoside-diphosphate
           reductase - Murid herpesvirus 4 (MuHV-4) (Murine
           gammaherpesvirus 68)
          Length = 783

 Score = 41.1 bits (92), Expect = 0.025
 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
 Frame = +1

Query: 7   LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKS--- 177
           L + +G  F   Y    ++  +   V  + +  A++   ++TG PY+L K + NR     
Sbjct: 326 LTNTYGYMFSIAYAGLVEQGAYEAVVPIKSVMFALVSCIIKTGGPYILNKKAINRHDWHE 385

Query: 178 -NQKNLGTIKCSNLCTEIVEYTSDD 249
            +      I C+NLC E+++Y  ++
Sbjct: 386 WSTHQYRAINCANLCAEVIQYPGEN 410



 Score = 41.1 bits (92), Expect = 0.025
 Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 13/91 (14%)
 Frame = +3

Query: 255 AVCNLASIALNMFVDDNK---------TY----NFKKLKEVTKTITENLNKIIDVNYYPV 395
           + CNLA+I L   ++D+K         TY    + ++L+  T+     +N  I     P 
Sbjct: 412 STCNLANICLPKCLEDDKFVSGKSCLLTYEREFSIERLERATEAAVFIINACIHGGTLPT 471

Query: 396 PEAKKSNLRHRPIGIGVQGLADAFILMRLPY 488
             A++     R +GIGVQGLAD F +M L Y
Sbjct: 472 QRARRGQ-SDRSMGIGVQGLADTFAMMGLGY 501


>UniRef50_A5FCJ4 Cluster: Ribonucleoside-diphosphate reductase,
           alpha chain; n=2; cellular organisms|Rep:
           Ribonucleoside-diphosphate reductase, alpha chain -
           Flavobacterium johnsoniae UW101
          Length = 565

 Score = 40.7 bits (91), Expect = 0.033
 Identities = 20/56 (35%), Positives = 34/56 (60%), Gaps = 4/56 (7%)
 Frame = +1

Query: 97  LWKAIIEAQVETGTPYMLFKDSCNRKSNQ----KNLGTIKCSNLCTEIVEYTSDDE 252
           +W  ++E++ + G PY+ F D+ N+   Q    +NL  I  SNLC+EI+  ++ DE
Sbjct: 223 IWAKVLESRQQKGLPYIFFSDNVNKNKPQVYKDQNL-RINASNLCSEIMLPSTHDE 277



 Score = 37.1 bits (82), Expect = 0.41
 Identities = 30/107 (28%), Positives = 48/107 (44%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431
           S +C L+S+ L ++ +   T   K        + +   +  + NYY +  A K   RHR 
Sbjct: 278 SFICCLSSMNLELYEEWKDTEAVKLAIFFLDAVLQEFIEKTEGNYY-LSAANKFAKRHRA 336

Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
           +G+GV G         +P+E  EA     +  K  +  A +AS ELA
Sbjct: 337 LGLGVLGWHSYLQKNMIPFEGMEAKMKTTEIFKHISDKADKASQELA 383


>UniRef50_Q5A0N2 Cluster: Putative uncharacterized protein; n=1;
           Candida albicans|Rep: Putative uncharacterized protein -
           Candida albicans (Yeast)
          Length = 135

 Score = 40.7 bits (91), Expect = 0.033
 Identities = 28/77 (36%), Positives = 37/77 (48%)
 Frame = +2

Query: 29  NLNPYMKHMKKKIDLXNK*GHKFFGKQ**KLK*RLVLHTCYLKIHVIEKVIRKI*VP*NV 208
           N   Y  + KKK  +      K  G    + K + V H CY+KIHV     ++  V  N+
Sbjct: 22  NSKNYTPNTKKKTVVDRPSKLKNCGMLFWEPKSKQVPHLCYIKIHVTTNPTKRTWVLSNL 81

Query: 209 VTCALK*LNIHLMMKCS 259
            TC +K LNI L MK S
Sbjct: 82  PTCVVKLLNISLQMKLS 98


>UniRef50_O41114 Cluster: A632L protein; n=1; Paramecium bursaria
           Chlorella virus 1|Rep: A632L protein - Paramecium
           bursaria Chlorella virus 1 (PBCV-1)
          Length = 72

 Score = 40.3 bits (90), Expect = 0.044
 Identities = 25/57 (43%), Positives = 28/57 (49%)
 Frame = -2

Query: 251 SSSDVYSTISVHRLLHFMVPKXXXXXXXLHESLNNMYGVPVST*ASIIAFQRTCALT 81
           SS DVYS IS+H+LL  MVP           SL   YG PVS     I F  + A T
Sbjct: 7   SSFDVYSRISIHKLLPRMVPALDCIFFLFTVSLLATYGCPVSMMVVTIVFHTSRAFT 63


>UniRef50_Q897Z5 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Clostridium|Rep: Ribonucleoside-diphosphate reductase -
           Clostridium tetani
          Length = 1047

 Score = 40.3 bits (90), Expect = 0.044
 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
 Frame = +3

Query: 261 CNLASIALNMFVDDN-KTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437
           CNLASI +  F D   K  + +    V   +   L   I    +P  +  +     R  G
Sbjct: 422 CNLASINIYKFYDGKEKNIDLESYLHVVGLVQLALEASIYWGQFPTKDIAQKTYMFRATG 481

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFT 539
           +G+  LA   +++  PY S EA N  +  + L T
Sbjct: 482 LGITNLASLLMVLGYPYNSTEARNISSALVGLLT 515


>UniRef50_A0LDD1 Cluster: Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent; n=24; Proteobacteria|Rep:
           Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent - Magnetococcus sp. (strain
           MC-1)
          Length = 707

 Score = 40.3 bits (90), Expect = 0.044
 Identities = 24/108 (22%), Positives = 48/108 (44%), Gaps = 4/108 (3%)
 Frame = +3

Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           C L S+ L  FV +  T    +++ + KEV    T  L+ +++++  P+P         R
Sbjct: 329 CLLGSVNLARFVKNPFTAKAEFDWARFKEVVAVFTRMLDNVVEIHGLPLPGQADEIAHKR 388

Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572
             G+G  GL     ++ + Y   +++   ++  +   +   E   ELA
Sbjct: 389 RHGMGFLGLGSTLTMLNMVYGDRQSVEFTSQVAREMALTGWEVGLELA 436


>UniRef50_P37426 Cluster: Ribonucleoside-diphosphate reductase 1
           subunit alpha; n=194; root|Rep:
           Ribonucleoside-diphosphate reductase 1 subunit alpha -
           Salmonella typhimurium
          Length = 761

 Score = 40.3 bits (90), Expect = 0.044
 Identities = 32/112 (28%), Positives = 50/112 (44%)
 Frame = +3

Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
           A+C L++  L       KT +  +L+E+       L+ ++D   YP+P AK+  +  R +
Sbjct: 460 ALCTLSAFNLGAI----KTLD--ELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTL 513

Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWEC 590
           GIGV   A         Y    A N  +K  +      L+AS ELA +   C
Sbjct: 514 GIGVINFAYWLAKNGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGAC 565


>UniRef50_Q8SCB8 Cluster: Large subunit ribonucleotide reductase;
           n=7; unclassified Myoviridae|Rep: Large subunit
           ribonucleotide reductase - Staphylococcus phage Twort
          Length = 705

 Score = 39.9 bits (89), Expect = 0.058
 Identities = 16/42 (38%), Positives = 25/42 (59%)
 Frame = +1

Query: 109 IIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVE 234
           I   Q+E+G PY+ + D+ N     K LG ++ SNLC E+ +
Sbjct: 347 IARTQLESGYPYVFYIDNANDNHPLKKLGKVQMSNLCCEVTQ 388



 Score = 35.9 bits (79), Expect = 0.94
 Identities = 31/137 (22%), Positives = 58/137 (42%), Gaps = 1/137 (0%)
 Frame = +3

Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYP-VPEAKKSNLRHRPI 434
           VC L S+ L   V+         LKE   +   +L+K+ D+   P +P  +K+N   R I
Sbjct: 411 VCTLGSLNLVNVVEKGL------LKESVDSGIRSLSKVTDLMNVPFLPSVQKANDELRAI 464

Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAP 614
           G+G            L Y S E+++  N         ++++S ELA +  +      ++ 
Sbjct: 465 GLGAMNWHGLLAKNMLSYGSRESLDIANSLFSAIRYYSIKSSMELAKETGKVFKGFKESE 524

Query: 615 ASRGHITVRHVELKIQP 665
              G +   +++   +P
Sbjct: 525 YYTGEVFSSYIQKSHEP 541


>UniRef50_Q66LW9 Cluster: Ribonucleoside-diphosphate reductase 1
           alpha chain; n=3; Enterobacteria phage T5|Rep:
           Ribonucleoside-diphosphate reductase 1 alpha chain -
           Bacteriophage T5
          Length = 811

 Score = 39.9 bits (89), Expect = 0.058
 Identities = 30/128 (23%), Positives = 58/128 (45%)
 Frame = +3

Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
           ++CNL  + L       +  +  + ++    + + ++ II++  YP P  + +  + R +
Sbjct: 514 SLCNLGGVVLG------RMESLAEWEKTCYILLKFVDTIIEIQDYPFPTMEYTAKKRRNV 567

Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAP 614
           GIG+   A A     L YE  EA N I++  +  +    +AS  LA +   C       P
Sbjct: 568 GIGLMNAAGAMAAEGLAYEGIEARNWIHREAEKLSYFLHKASVRLAKEQGACEWFNRTKP 627

Query: 615 ASRGHITV 638
            S+G + +
Sbjct: 628 -SKGILVI 634


>UniRef50_Q6YRG1 Cluster: Ribonucleoside-diphosphate reductase; n=4;
           Candidatus Phytoplasma|Rep: Ribonucleoside-diphosphate
           reductase - Onion yellows phytoplasma
          Length = 769

 Score = 39.1 bits (87), Expect = 0.10
 Identities = 21/53 (39%), Positives = 34/53 (64%)
 Frame = +1

Query: 82  VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVEYT 240
           +  + L + I   Q E+G PY++F D+ N ++N  +L  +K SNLCTEI++ T
Sbjct: 409 INPRQLLELIAHMQGESGYPYLMFCDNTN-QANTSDL-KVKFSNLCTEILQPT 459


>UniRef50_Q1ISM3 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Bacteria|Rep: Ribonucleoside-diphosphate reductase -
           Acidobacteria bacterium (strain Ellin345)
          Length = 1004

 Score = 39.1 bits (87), Expect = 0.10
 Identities = 22/80 (27%), Positives = 36/80 (45%)
 Frame = +3

Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
           + CNLAS+ L  F   N T++    +            ++D   YP     K++  +RP+
Sbjct: 410 SACNLASLNLMKFAP-NGTFDVAAYRHACAITITAQEILVDNAGYPTESIMKNSHDYRPL 468

Query: 435 GIGVQGLADAFILMRLPYES 494
           G+G   L    +   LPY+S
Sbjct: 469 GLGYANLGALLMAAGLPYDS 488



 Score = 32.7 bits (71), Expect = 8.8
 Identities = 19/56 (33%), Positives = 25/56 (44%)
 Frame = +1

Query: 58  KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           K    V   +A+ L   I EA  + G P M +  + NR    KN   I  SN C+E
Sbjct: 348 KSGDVVKTFKARWLLSKISEATWQCGDPGMQYDTTVNRWHTSKNTARINASNPCSE 403


>UniRef50_Q0W4L0 Cluster: Putative uncharacterized protein; n=2;
           uncultured methanogenic archaeon RC-I|Rep: Putative
           uncharacterized protein - Uncultured methanogenic
           archaeon RC-I
          Length = 269

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
 Frame = -3

Query: 370 ILFKFSVIVLVTSFNFLKL-YVL-LSSTNIFSAIEAKLHTALHHQMYIQLFQCTGYYILW 197
           I F     VL   FN L L +VL LSST  F ++   + TAL  QM      C  + IL+
Sbjct: 131 IYFNDPTEVLPVIFNILPLMFVLSLSSTMFFYSLTLLICTALKDQMLSFFTSCLSWIILF 190

Query: 196 YLN----FSDYFFYYMN 158
           YL     F+ Y  YY+N
Sbjct: 191 YLINDDWFAGYISYYLN 207


>UniRef50_O55567 Cluster: P25; n=1; Leucania separata nuclear
           polyhedrosis virus|Rep: P25 - Leucania separata nuclear
           polyhedrosis virus (LsNPV)
          Length = 222

 Score = 38.3 bits (85), Expect = 0.18
 Identities = 19/44 (43%), Positives = 26/44 (59%)
 Frame = +1

Query: 1   PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVET 132
           P L D +G +FE  Y+ YE + +F  Q+ A  L + IIE Q ET
Sbjct: 158 PKLNDTYGDDFEYWYKHYEDKGQFREQMPAVTLMRNIIEIQAET 201


>UniRef50_A7HCF4 Cluster: Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent; n=3; Cystobacterineae|Rep:
           Ribonucleoside-diphosphate reductase,
           adenosylcobalamin-dependent - Anaeromyxobacter sp.
           Fw109-5
          Length = 929

 Score = 37.9 bits (84), Expect = 0.23
 Identities = 20/80 (25%), Positives = 36/80 (45%)
 Frame = +3

Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434
           + CNLAS+ L  F   +  ++ +  K            ++    YP  +  K++  +RP+
Sbjct: 377 SACNLASLNLMHFRGIDGAFDVESFKRAVDLTVLAQEILVSNAKYPTEQIGKNSEDYRPL 436

Query: 435 GIGVQGLADAFILMRLPYES 494
           G+G   L    +   LPY+S
Sbjct: 437 GLGYANLGALLMASGLPYDS 456


>UniRef50_UPI000155442E Cluster: hypothetical protein ORF046; n=1;
           Pseudomonas phage M6|Rep: hypothetical protein ORF046 -
           Pseudomonas phage M6
          Length = 620

 Score = 37.1 bits (82), Expect = 0.41
 Identities = 16/62 (25%), Positives = 34/62 (54%)
 Frame = +3

Query: 312 YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYE 491
           +++ + +E    +   ++ ++D   YP+P+ K+     R +G+G+ GLA+A   +   Y 
Sbjct: 335 FDWDQYREDIPQVVRAMDNVVDRAIYPLPQQKQEAKDKRRMGLGITGLANAAEALGHEYG 394

Query: 492 SP 497
           SP
Sbjct: 395 SP 396



 Score = 34.7 bits (76), Expect = 2.2
 Identities = 18/49 (36%), Positives = 26/49 (53%)
 Frame = +1

Query: 79  QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225
           +V A+ LW AI+    +   P +LF D+ NR +N     TI  +N C E
Sbjct: 257 EVDARALWDAIMRGTWDWAEPGVLFIDAINRMNNLWYCETIAATNPCGE 305


>UniRef50_A3XHF8 Cluster: Ribonucleoside-diphosphate reductase,
           alpha subunit 1; n=10; root|Rep:
           Ribonucleoside-diphosphate reductase, alpha subunit 1 -
           Leeuwenhoekiella blandensis MED217
          Length = 600

 Score = 36.7 bits (81), Expect = 0.54
 Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 3/54 (5%)
 Frame = +1

Query: 97  LWKAIIEAQVETGTPYMLFKDSCN--RKSNQKNLG-TIKCSNLCTEIVEYTSDD 249
           +W  +++ + E G PY+ + D+ N  +    K+ G  I  SNLCTEI+  +SD+
Sbjct: 247 VWAKVLQRRGEMGYPYIFYTDNANNGKPDVYKDKGHDIYASNLCTEIMLPSSDE 300


>UniRef50_Q6LQZ0 Cluster: Putative uncharacterized protein; n=2;
           Photobacterium profundum|Rep: Putative uncharacterized
           protein - Photobacterium profundum (Photobacterium sp.
           (strain SS9))
          Length = 173

 Score = 35.9 bits (79), Expect = 0.94
 Identities = 19/61 (31%), Positives = 31/61 (50%)
 Frame = +1

Query: 28  EFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKC 207
           +F++LYE  E     V  + +    KA + AQ   GTPY LF  +C +   Q +   ++C
Sbjct: 42  QFDTLYEFSEGRAILVSSITSDEPEKAYLYAQQYLGTPYNLFNRNCEQFVRQSHGLPVEC 101

Query: 208 S 210
           +
Sbjct: 102 T 102


>UniRef50_Q7TDH5 Cluster: Ribonucleoside-diphosphate reductase; n=2;
           Haloviruses|Rep: Ribonucleoside-diphosphate reductase -
           Halovirus HF1
          Length = 805

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 16/63 (25%), Positives = 32/63 (50%)
 Frame = +3

Query: 315 NFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYES 494
           +F +L    +  T  L+ ++  + +P+PE  +     R IG+G+ G A     M +PY +
Sbjct: 433 DFNELDRTIEAGTRFLDNVVTQSDFPIPEITERVGGMRKIGLGIMGFAQMLYQMGVPYGT 492

Query: 495 PEA 503
            ++
Sbjct: 493 QDS 495


>UniRef50_Q18GD3 Cluster: Ribonucleoside-diphosphate reductase alpha
            subunit; n=1; Haloquadratum walsbyi DSM 16790|Rep:
            Ribonucleoside-diphosphate reductase alpha subunit -
            Haloquadratum walsbyi (strain DSM 16790)
          Length = 1909

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 17/51 (33%), Positives = 29/51 (56%)
 Frame = +3

Query: 351  TENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEA 503
            T  L  ++ ++ +PV E + +    R IG+G+ GLA  +I + + Y S EA
Sbjct: 910  TRFLENVVTMSDFPVDEIEATVRDMRKIGLGIMGLAQLYIQIGVRYGSQEA 960


>UniRef50_O31875 Cluster: Ribonucleoside-diphosphate reductase; n=13;
            root|Rep: Ribonucleoside-diphosphate reductase - Bacillus
            subtilis
          Length = 1084

 Score = 34.7 bits (76), Expect = 2.2
 Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 1/110 (0%)
 Frame = +3

Query: 261  CNLASIAL-NMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437
            CNL S+ + N+  + +     +   +   T+T   N I++      P   ++N   R IG
Sbjct: 793  CNLGSMNIVNVMSNQSIASTVRIAIDSLTTVTRKTN-IVNA-----PAVARANTLMRSIG 846

Query: 438  IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWE 587
            +G   L        + YES EA +  N Y  +    +L+ S E+A +  E
Sbjct: 847  LGQMNLHGFLAQNNIAYESEEAKDFANTYFMMVNFYSLQRSMEIARETGE 896



 Score = 33.9 bits (74), Expect = 3.8
 Identities = 14/44 (31%), Positives = 27/44 (61%)
 Frame = +1

Query: 88  AQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219
           A+ L + +   + E+G PY++F D+ N+    +++  +K SNLC
Sbjct: 338 ARKLLEQLAILRSESGYPYIMFADNVNKVHPNEHISKVKFSNLC 381


>UniRef50_Q5CHN1 Cluster: Putative uncharacterized protein; n=1;
           Cryptosporidium hominis|Rep: Putative uncharacterized
           protein - Cryptosporidium hominis
          Length = 76

 Score = 33.9 bits (74), Expect = 3.8
 Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 1/54 (1%)
 Frame = -2

Query: 470 NKSISKTLNTYSNRSMSKIRFFCFR-NRVIIYINDFIQIFCYSFSNFF*FLKVI 312
           +K + K    Y + ++SK +F   + N + I+IN F  +  +S SNFF FL ++
Sbjct: 23  SKILKKNNRRYLS-NISKKKFVLIKQNNITIHINKFFFLLFFSLSNFFLFLNIV 75


>UniRef50_O69981 Cluster: Vitamin B12-dependent ribonucleotide
           reductase; n=12; Actinomycetales|Rep: Vitamin
           B12-dependent ribonucleotide reductase - Streptomyces
           coelicolor
          Length = 967

 Score = 33.9 bits (74), Expect = 3.8
 Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 4/111 (3%)
 Frame = +3

Query: 261 CNLASIALNMFVDD----NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428
           CNLAS+ L  F+ D    N++++ ++  +V + +   ++  I    +P  +  ++    R
Sbjct: 377 CNLASLNLMKFLKDDGKGNQSFDAERFSKVVELVITAMDISICFADFPTQKIGENTRAFR 436

Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKV 581
            +GIG   L    +     Y+S            L T  +   S ELAA V
Sbjct: 437 QLGIGYANLGALLMATGHAYDSDGGRALAGAITSLMTGTSYRRSAELAAIV 487


>UniRef50_Q89MB9 Cluster: Vitamin B12-dependent ribonucleotide
           reductase; n=82; root|Rep: Vitamin B12-dependent
           ribonucleotide reductase - Bradyrhizobium japonicum
          Length = 1254

 Score = 33.9 bits (74), Expect = 3.8
 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 1/108 (0%)
 Frame = +3

Query: 261 CNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437
           CNLAS  L  F +   K ++ +  + + +  T  L   + +  +P     + +   R +G
Sbjct: 487 CNLASANLLTFYNVATKHFDVEGYEHLCRLWTVVLEISVMMAQFPSKAIAELSYEFRTLG 546

Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKV 581
           +G   +    + M LPY+S E          + T    + S E+AA++
Sbjct: 547 LGYANIGGLLMTMGLPYDSKEGRALCGALTAVMTGITYKTSAEIAAEL 594


>UniRef50_Q7RJL4 Cluster: Putative uncharacterized protein PY03245;
           n=4; Plasmodium (Vinckeia)|Rep: Putative uncharacterized
           protein PY03245 - Plasmodium yoelii yoelii
          Length = 409

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 17/70 (24%), Positives = 34/70 (48%)
 Frame = +3

Query: 291 FVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFI 470
           F++DNK Y + K+ E++ + + NLNK      Y     +   L +  I + +    + +I
Sbjct: 139 FIEDNKDYLYNKIGEISNSFSTNLNK------YTTCMHELYGLYNESIDVSMDNFRNGYI 192

Query: 471 LMRLPYESPE 500
            M++ +   E
Sbjct: 193 FMQIHFSKHE 202


>UniRef50_A2FWX8 Cluster: Putative uncharacterized protein; n=1;
            Trichomonas vaginalis G3|Rep: Putative uncharacterized
            protein - Trichomonas vaginalis G3
          Length = 3852

 Score = 33.5 bits (73), Expect = 5.0
 Identities = 18/44 (40%), Positives = 27/44 (61%)
 Frame = +3

Query: 252  SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVN 383
            SA      I LNM + D+    F+K + + KTI+ENL KII+++
Sbjct: 1860 SATLKYPEIPLNMILMDSNYNGFEK-EMIKKTISENLPKIIEIS 1902


>UniRef50_Q7REC9 Cluster: Putative uncharacterized protein PY05136;
           n=3; Plasmodium (Vinckeia)|Rep: Putative uncharacterized
           protein PY05136 - Plasmodium yoelii yoelii
          Length = 368

 Score = 33.1 bits (72), Expect = 6.6
 Identities = 18/55 (32%), Positives = 30/55 (54%)
 Frame = +3

Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSN 416
           S    LAS   + F D+N   + +K++E  K ++E++  II     P+PEA+  N
Sbjct: 309 SVATTLASSFADTFKDENGKPDKRKMQEQGKLMSEHMQHIIKEVSKPLPEAQTKN 363


>UniRef50_A0DYW6 Cluster: Chromosome undetermined scaffold_7, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_7,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 782

 Score = 33.1 bits (72), Expect = 6.6
 Identities = 15/49 (30%), Positives = 28/49 (57%)
 Frame = +3

Query: 264 NLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKK 410
           N  S  L +F+   ++YN  + +++ K IT N+  I+D N  PV + ++
Sbjct: 129 NCLSYFLLLFLFKKQSYNLNQAQDIIKQITSNIYVILDNNLNPVYDEER 177


>UniRef50_UPI00006CE942 Cluster: hypothetical repeat containing
            protein; n=1; Tetrahymena thermophila SB210|Rep:
            hypothetical repeat containing protein - Tetrahymena
            thermophila SB210
          Length = 2307

 Score = 32.7 bits (71), Expect = 8.8
 Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
 Frame = +3

Query: 252  SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDV--NYYPVPEAKK 410
            S  C+ ASI + +F+ DN +YN+  +K + K I E L + ID    Y P  E K+
Sbjct: 2068 STNCSAASILIGVFIYDN-SYNY-LIKGIKKIIIEKLAEKIDYFKKYLPKEEQKR 2120


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 618,219,844
Number of Sequences: 1657284
Number of extensions: 11156924
Number of successful extensions: 32211
Number of sequences better than 10.0: 147
Number of HSP's better than 10.0 without gapping: 30431
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 32039
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 54545459628
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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