BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= prgv0266 (693 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q4S8W6 Cluster: Ribonucleoside-diphosphate reductase; n... 163 4e-39 UniRef50_P07742 Cluster: Ribonucleoside-diphosphate reductase la... 153 5e-36 UniRef50_P23921 Cluster: Ribonucleoside-diphosphate reductase la... 149 5e-35 UniRef50_Q01H73 Cluster: Ribonucleoside-diphosphate reductase; n... 141 1e-32 UniRef50_Q9SJ20 Cluster: Ribonucleoside-diphosphate reductase la... 136 4e-31 UniRef50_Q8JKL8 Cluster: Ribonucleoside-diphosphate reductase; n... 133 4e-30 UniRef50_O12935 Cluster: Ribonucleoside-diphosphate reductase; n... 128 2e-28 UniRef50_Q75BW6 Cluster: Ribonucleoside-diphosphate reductase; n... 118 2e-25 UniRef50_Q9QAL9 Cluster: Ribonucleoside-diphosphate reductase; n... 109 5e-23 UniRef50_Q7T6Y8 Cluster: Ribonucleoside-diphosphate reductase la... 100 3e-20 UniRef50_Q6MLM3 Cluster: Ribonucleoside-diphosphate reductase al... 96 8e-19 UniRef50_P26685 Cluster: Ribonucleoside-diphosphate reductase la... 93 4e-18 UniRef50_O41111 Cluster: Ribonucleoside-diphosphate reductase; n... 93 6e-18 UniRef50_A7IY07 Cluster: Putative uncharacterized protein B832R;... 88 2e-16 UniRef50_Q4J4L6 Cluster: Ribonucleoside-diphosphate reductase; n... 88 2e-16 UniRef50_Q9HMU3 Cluster: Ribonucleoside-diphosphate reductase; n... 85 2e-15 UniRef50_Q3AEA3 Cluster: Ribonucleoside-diphosphate reductase, a... 84 4e-15 UniRef50_O84834 Cluster: Ribonucleoside-diphosphate reductase su... 83 5e-15 UniRef50_Q67KQ2 Cluster: Ribonucleoside-diphosphate reductase; n... 78 2e-13 UniRef50_A2XAQ8 Cluster: Ribonucleoside-diphosphate reductase; n... 78 2e-13 UniRef50_Q39JT6 Cluster: Ribonucleoside-diphosphate reductase; n... 78 2e-13 UniRef50_Q3E5I1 Cluster: Ribonucleoside-diphosphate reductase; n... 77 5e-13 UniRef50_P74911 Cluster: Ribonucleoside-diphosphate reductase; n... 76 1e-12 UniRef50_UPI0000F5175D Cluster: hypothetical protein Faci_030006... 75 1e-12 UniRef50_Q8R7R2 Cluster: Ribonucleoside-diphosphate reductase; n... 75 2e-12 UniRef50_Q6A5Y5 Cluster: Ribonucleoside-diphosphate reductase al... 75 2e-12 UniRef50_A4L245 Cluster: Ribonucleotide reductase large subunit;... 74 4e-12 UniRef50_Q8TQ86 Cluster: Ribonucleoside-diphosphate reductase; n... 73 5e-12 UniRef50_Q6R7H4 Cluster: Ribonucleoside-diphosphate reductase; n... 73 9e-12 UniRef50_Q6UDJ2 Cluster: Ribonucleoside-diphosphate reductase; n... 71 2e-11 UniRef50_Q91ES8 Cluster: ORF127 RR1; n=1; Cydia pomonella granul... 71 3e-11 UniRef50_A2DI13 Cluster: Ribonucleoside-diphosphate reductase; n... 71 3e-11 UniRef50_A6QCU9 Cluster: Ribonucleoside-diphosphate reductase, a... 70 6e-11 UniRef50_O26748 Cluster: Ribonucleoside-diphosphate reductase; n... 70 6e-11 UniRef50_Q67SN6 Cluster: Ribonucleoside-diphosphate reductase; n... 69 1e-10 UniRef50_A0RYG3 Cluster: Ribonucleoside-diphosphate reductase; n... 69 1e-10 UniRef50_P55982 Cluster: Ribonucleoside-diphosphate reductase su... 69 1e-10 UniRef50_Q647Z9 Cluster: Ribonucleoside-diphosphate reductase; n... 69 1e-10 UniRef50_Q6QXF6 Cluster: ORF37; n=4; Baculoviridae|Rep: ORF37 - ... 68 2e-10 UniRef50_Q6AJC4 Cluster: Ribonucleoside-diphosphate reductase; n... 68 2e-10 UniRef50_Q6VMN2 Cluster: Ribonucleoside-diphosphate reductase; n... 67 3e-10 UniRef50_A5FSC1 Cluster: Ribonucleoside-diphosphate reductase, a... 67 4e-10 UniRef50_Q9UYA0 Cluster: Ribonucleoside-diphosphate reductase; n... 67 4e-10 UniRef50_P95484 Cluster: Ribonucleoside-diphosphate reductase; n... 67 4e-10 UniRef50_A3QTY4 Cluster: Ribonucleotide reductase large subunit;... 66 1e-09 UniRef50_Q8VKI9 Cluster: Ribonucleoside-diphosphate reductase; n... 65 1e-09 UniRef50_O83972 Cluster: Ribonucleoside-diphosphate reductase su... 65 1e-09 UniRef50_O66503 Cluster: Ribonucleoside-diphosphate reductase su... 65 1e-09 UniRef50_Q2VSI0 Cluster: Ribonucleoside-diphosphate reductase; n... 64 4e-09 UniRef50_Q5KX82 Cluster: Ribonucleoside-diphosphate reductase; n... 64 4e-09 UniRef50_A0B8R8 Cluster: Ribonucleoside-diphosphate reductase; n... 63 5e-09 UniRef50_P74240 Cluster: Ribonucleoside-diphosphate reductase su... 63 7e-09 UniRef50_Q18UV0 Cluster: Ribonucleoside-diphosphate reductase; n... 62 9e-09 UniRef50_Q4C9K9 Cluster: Ribonucleoside-diphosphate reductase; n... 62 1e-08 UniRef50_Q97ZH9 Cluster: Ribonucleoside-diphosphate reductase; n... 62 1e-08 UniRef50_UPI00015BC77F Cluster: UPI00015BC77F related cluster; n... 62 2e-08 UniRef50_Q5SM68 Cluster: Ribonucleoside-diphosphate reductase; n... 60 4e-08 UniRef50_A5TVY2 Cluster: Ribonucleoside-diphosphate reductase; n... 60 4e-08 UniRef50_Q9IBT4 Cluster: Ribonucleoside-diphosphate reductase; n... 59 9e-08 UniRef50_Q5LNK9 Cluster: Ribonucleoside-diphosphate reductase, p... 59 1e-07 UniRef50_A3H704 Cluster: Ribonucleoside-diphosphate reductase; n... 59 1e-07 UniRef50_A3JKM6 Cluster: Ribonucleoside reductase; n=1; Marinoba... 58 2e-07 UniRef50_Q9PE32 Cluster: Ribonucleoside-diphosphate reductase; n... 58 3e-07 UniRef50_A1YJD3 Cluster: Ribonucleoside-diphosphate reductase; n... 57 4e-07 UniRef50_O33839 Cluster: Ribonucleoside-diphosphate reductase; n... 57 4e-07 UniRef50_A7I485 Cluster: Ribonucleoside-diphosphate reductase, a... 57 4e-07 UniRef50_Q5P1D5 Cluster: Ribonucleotide reductase, Coenzyme B12-... 56 6e-07 UniRef50_Q2RP92 Cluster: Ribonucleotide reductase large subunit;... 56 6e-07 UniRef50_A6NX38 Cluster: Ribonucleoside-diphosphate reductase; n... 56 6e-07 UniRef50_Q9YA77 Cluster: Ribonucleoside-diphosphate reductase; n... 56 6e-07 UniRef50_P09853 Cluster: Ribonucleoside-diphosphate reductase la... 56 6e-07 UniRef50_A7KUZ9 Cluster: Nrd alpha subunit; n=1; Bacillus phage ... 56 8e-07 UniRef50_A7HK53 Cluster: Ribonucleoside-diphosphate reductase, a... 56 1e-06 UniRef50_Q9RZL7 Cluster: Ribonucleoside-diphosphate reductase; n... 55 1e-06 UniRef50_Q21U31 Cluster: Ribonucleoside-diphosphate reductase; n... 55 1e-06 UniRef50_A7IYE5 Cluster: Putivate ribonucleotide reductase; n=1;... 55 1e-06 UniRef50_Q89YE5 Cluster: Ribonucleoside-diphosphate reductase; n... 55 2e-06 UniRef50_Q2LW62 Cluster: Ribonucleoside-diphosphate reductase al... 54 3e-06 UniRef50_Q18BC3 Cluster: Putative ribonucleotide-diphosphate red... 54 4e-06 UniRef50_Q01037 Cluster: Ribonucleoside-diphosphate reductase la... 54 4e-06 UniRef50_A3EPA5 Cluster: Ribonucleoside-diphosphate reductase; n... 53 6e-06 UniRef50_A2PYM5 Cluster: Ribonucleoside-diphosphate reductase al... 53 6e-06 UniRef50_O36411 Cluster: Ribonucleoside-diphosphate reductase; n... 53 8e-06 UniRef50_A3W1N9 Cluster: Ribonucleoside-diphosphate reductase; n... 53 8e-06 UniRef50_A0MN59 Cluster: Ribonucleotide reductase alpha subunit;... 53 8e-06 UniRef50_P50643 Cluster: Ribonucleoside-diphosphate reductase la... 53 8e-06 UniRef50_Q7NEB4 Cluster: Gll3966 protein; n=1; Gloeobacter viola... 52 1e-05 UniRef50_A3I5A9 Cluster: Ribonucleoside-diphosphate reductase; n... 52 1e-05 UniRef50_Q7UI46 Cluster: Vitamin B12-dependent ribonucleotide re... 52 2e-05 UniRef50_A4IY36 Cluster: Ribonucleoside-diphosphate reductase, a... 51 2e-05 UniRef50_Q1FPU1 Cluster: Ribonucleoside-diphosphate reductase; n... 51 3e-05 UniRef50_Q8Y2Y6 Cluster: Ribonucleoside-diphosphate reductase; n... 50 4e-05 UniRef50_A1HDY4 Cluster: Ribonucleoside-diphosphate reductase; n... 50 4e-05 UniRef50_Q3B5C1 Cluster: Ribonucleotide reductase family protein... 50 5e-05 UniRef50_Q3SMN2 Cluster: Ribonucleoside-diphosphate reductase al... 50 7e-05 UniRef50_Q1J1T0 Cluster: Ribonucleoside-diphosphate reductase; n... 50 7e-05 UniRef50_Q120H3 Cluster: Ribonucleotide reductase large subunit;... 50 7e-05 UniRef50_Q0LX20 Cluster: Ribonucleoside-diphosphate reductase; n... 49 9e-05 UniRef50_O55716 Cluster: Ribonucleoside-diphosphate reductase; n... 48 2e-04 UniRef50_Q6MNP6 Cluster: Vitamin B12-dependent ribonucleotide re... 48 2e-04 UniRef50_Q88YQ4 Cluster: Ribonucleoside-diphosphate reductase, a... 48 2e-04 UniRef50_A5JBG3 Cluster: Ribonucleotide reductase, large subunit... 48 2e-04 UniRef50_UPI00004BA6C5 Cluster: UPI00004BA6C5 related cluster; n... 48 3e-04 UniRef50_Q196Z5 Cluster: Ribonucleoside-diphosphate reductase; n... 48 3e-04 UniRef50_A4WLF4 Cluster: Ribonucleoside-diphosphate reductase, a... 48 3e-04 UniRef50_Q9RRW1 Cluster: Ribonucleoside-diphosphate reductase; n... 46 7e-04 UniRef50_Q604J6 Cluster: Ribonucleoside-diphosphate reductase; n... 46 9e-04 UniRef50_Q8ZTP7 Cluster: Ribonucleoside-diphosphate reductase; n... 45 0.002 UniRef50_P78027 Cluster: Ribonucleoside-diphosphate reductase su... 45 0.002 UniRef50_A7CVZ3 Cluster: Ribonucleoside-diphosphate reductase pr... 45 0.002 UniRef50_A1W357 Cluster: Ribonucleoside-diphosphate reductase; n... 45 0.002 UniRef50_A1TJY2 Cluster: Ribonucleoside-diphosphate reductase, a... 44 0.003 UniRef50_P0A5W9 Cluster: Ribonucleoside-diphosphate reductase su... 44 0.003 UniRef50_Q2S5T5 Cluster: Ribonucleoside-diphosphate reductase, a... 44 0.004 UniRef50_P03190 Cluster: Ribonucleoside-diphosphate reductase la... 44 0.004 UniRef50_Q9HPG8 Cluster: Ribonucleoside-diphosphate reductase; n... 42 0.011 UniRef50_Q5DN91 Cluster: Ribonucleotide reductase; n=1; Phage ph... 42 0.014 UniRef50_Q2NME4 Cluster: Ribonucleoside-diphosphate reductase la... 42 0.019 UniRef50_P50620 Cluster: Ribonucleoside-diphosphate reductase su... 42 0.019 UniRef50_O41962 Cluster: Ribonucleoside-diphosphate reductase; n... 41 0.025 UniRef50_A5FCJ4 Cluster: Ribonucleoside-diphosphate reductase, a... 41 0.033 UniRef50_Q5A0N2 Cluster: Putative uncharacterized protein; n=1; ... 41 0.033 UniRef50_O41114 Cluster: A632L protein; n=1; Paramecium bursaria... 40 0.044 UniRef50_Q897Z5 Cluster: Ribonucleoside-diphosphate reductase; n... 40 0.044 UniRef50_A0LDD1 Cluster: Ribonucleoside-diphosphate reductase, a... 40 0.044 UniRef50_P37426 Cluster: Ribonucleoside-diphosphate reductase 1 ... 40 0.044 UniRef50_Q8SCB8 Cluster: Large subunit ribonucleotide reductase;... 40 0.058 UniRef50_Q66LW9 Cluster: Ribonucleoside-diphosphate reductase 1 ... 40 0.058 UniRef50_Q6YRG1 Cluster: Ribonucleoside-diphosphate reductase; n... 39 0.10 UniRef50_Q1ISM3 Cluster: Ribonucleoside-diphosphate reductase; n... 39 0.10 UniRef50_Q0W4L0 Cluster: Putative uncharacterized protein; n=2; ... 39 0.13 UniRef50_O55567 Cluster: P25; n=1; Leucania separata nuclear pol... 38 0.18 UniRef50_A7HCF4 Cluster: Ribonucleoside-diphosphate reductase, a... 38 0.23 UniRef50_UPI000155442E Cluster: hypothetical protein ORF046; n=1... 37 0.41 UniRef50_A3XHF8 Cluster: Ribonucleoside-diphosphate reductase, a... 37 0.54 UniRef50_Q6LQZ0 Cluster: Putative uncharacterized protein; n=2; ... 36 0.94 UniRef50_Q7TDH5 Cluster: Ribonucleoside-diphosphate reductase; n... 35 1.6 UniRef50_Q18GD3 Cluster: Ribonucleoside-diphosphate reductase al... 35 1.6 UniRef50_O31875 Cluster: Ribonucleoside-diphosphate reductase; n... 35 2.2 UniRef50_Q5CHN1 Cluster: Putative uncharacterized protein; n=1; ... 34 3.8 UniRef50_O69981 Cluster: Vitamin B12-dependent ribonucleotide re... 34 3.8 UniRef50_Q89MB9 Cluster: Vitamin B12-dependent ribonucleotide re... 34 3.8 UniRef50_Q7RJL4 Cluster: Putative uncharacterized protein PY0324... 33 5.0 UniRef50_A2FWX8 Cluster: Putative uncharacterized protein; n=1; ... 33 5.0 UniRef50_Q7REC9 Cluster: Putative uncharacterized protein PY0513... 33 6.6 UniRef50_A0DYW6 Cluster: Chromosome undetermined scaffold_7, who... 33 6.6 UniRef50_UPI00006CE942 Cluster: hypothetical repeat containing p... 33 8.8 >UniRef50_Q4S8W6 Cluster: Ribonucleoside-diphosphate reductase; n=3; Tetraodontidae|Rep: Ribonucleoside-diphosphate reductase - Tetraodon nigroviridis (Green puffer) Length = 898 Score = 163 bits (396), Expect = 4e-39 Identities = 83/124 (66%), Positives = 94/124 (75%) Frame = +3 Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 AVCNLASIALNM+V +TY+F KL VTKTI +NLNKIID+NYYPVPEAK+SNLRHRPI Sbjct: 494 AVCNLASIALNMYVTPQRTYDFHKLASVTKTIVKNLNKIIDINYYPVPEAKRSNLRHRPI 553 Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAP 614 GIGVQGLADAFILMR PYESPEA + + ALEASCELAA+ + +P Sbjct: 554 GIGVQGLADAFILMRHPYESPEAQLLNTQIFETIYHAALEASCELAAEFGPYQTY-AGSP 612 Query: 615 ASRG 626 SRG Sbjct: 613 VSRG 616 Score = 147 bits (356), Expect = 3e-34 Identities = 65/85 (76%), Positives = 72/85 (84%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 PGL DCWG+EFE LY YEKE R V+AQ LW AIIE+Q ETGTPYML+KD+CNRKSN Sbjct: 409 PGLTDCWGEEFEELYTRYEKEGRAKRVVKAQQLWYAIIESQTETGTPYMLYKDACNRKSN 468 Query: 181 QKNLGTIKCSNLCTEIVEYTSDDEV 255 Q+NLGTI+CSNLCTEIVEYTS DEV Sbjct: 469 QQNLGTIRCSNLCTEIVEYTSKDEV 493 >UniRef50_P07742 Cluster: Ribonucleoside-diphosphate reductase large subunit; n=93; root|Rep: Ribonucleoside-diphosphate reductase large subunit - Mus musculus (Mouse) Length = 792 Score = 153 bits (370), Expect = 5e-36 Identities = 76/107 (71%), Positives = 86/107 (80%), Gaps = 1/107 (0%) Frame = +3 Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 AVCNLAS+ALNM+V TY+F+KL EVTK I NLNKIID+NYYP+PEA SN RHRPI Sbjct: 442 AVCNLASLALNMYVTPEHTYDFEKLAEVTKVIVRNLNKIIDINYYPIPEAHLSNKRHRPI 501 Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYL-KLFTMGALEASCELA 572 GIGVQGLADAFILMR P+ESPEA +NK + + GALEASCELA Sbjct: 502 GIGVQGLADAFILMRYPFESPEA-QLLNKQIFETIYYGALEASCELA 547 Score = 145 bits (351), Expect = 1e-33 Identities = 65/85 (76%), Positives = 73/85 (85%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 PGL + WG+EFE LYE+YEK+ R V+AQ LW AIIE+Q ETGTPYML+KDSCNRKSN Sbjct: 357 PGLDEVWGEEFEKLYESYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSN 416 Query: 181 QKNLGTIKCSNLCTEIVEYTSDDEV 255 Q+NLGTIKCSNLCTEIVEYTS DEV Sbjct: 417 QQNLGTIKCSNLCTEIVEYTSKDEV 441 Score = 39.9 bits (89), Expect = 0.058 Identities = 18/35 (51%), Positives = 23/35 (65%) Frame = +2 Query: 509 LNQQIFETIYYGSTRGKL*TSSKSMGVYDTYDGCP 613 LN+QIFETIYYG+ +K G Y+TY+G P Sbjct: 527 LNKQIFETIYYGALEASC-ELAKEYGPYETYEGSP 560 >UniRef50_P23921 Cluster: Ribonucleoside-diphosphate reductase large subunit; n=110; root|Rep: Ribonucleoside-diphosphate reductase large subunit - Homo sapiens (Human) Length = 792 Score = 149 bits (362), Expect = 5e-35 Identities = 75/107 (70%), Positives = 85/107 (79%), Gaps = 1/107 (0%) Frame = +3 Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 AVCNLAS+ALNM+V TY+FKKL EVTK + NLNKIID+NYYPVPEA SN RHRPI Sbjct: 442 AVCNLASLALNMYVTSEHTYDFKKLAEVTKVVVRNLNKIIDINYYPVPEACLSNKRHRPI 501 Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYL-KLFTMGALEASCELA 572 GIGVQGLADAFILMR P+ES EA +NK + + GALEASC+LA Sbjct: 502 GIGVQGLADAFILMRYPFESAEA-QLLNKQIFETIYYGALEASCDLA 547 Score = 142 bits (345), Expect = 6e-33 Identities = 64/85 (75%), Positives = 72/85 (84%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 PGL + WG+EFE LY +YEK+ R V+AQ LW AIIE+Q ETGTPYML+KDSCNRKSN Sbjct: 357 PGLDEVWGEEFEKLYASYEKQGRVRKVVKAQQLWYAIIESQTETGTPYMLYKDSCNRKSN 416 Query: 181 QKNLGTIKCSNLCTEIVEYTSDDEV 255 Q+NLGTIKCSNLCTEIVEYTS DEV Sbjct: 417 QQNLGTIKCSNLCTEIVEYTSKDEV 441 Score = 41.9 bits (94), Expect = 0.014 Identities = 25/76 (32%), Positives = 36/76 (47%) Frame = +2 Query: 464 FYFNAFTLRKSRSY*LNQQIFETIYYGSTRGKL*TSSKSMGVYDTYDGCPCKSRAYYSTT 643 F + + + LN+QIFETIYYG+ +K G Y+TY+G P S+ Sbjct: 512 FILMRYPFESAEAQLLNKQIFETIYYGALEASC-DLAKEQGPYETYEGSPV-SKGILQYD 569 Query: 644 CGIKNPTRFYGDWDLL 691 PT + DW +L Sbjct: 570 MWNVTPTDLW-DWKVL 584 >UniRef50_Q01H73 Cluster: Ribonucleoside-diphosphate reductase; n=1; Ostreococcus tauri|Rep: Ribonucleoside-diphosphate reductase - Ostreococcus tauri Length = 840 Score = 141 bits (342), Expect = 1e-32 Identities = 62/84 (73%), Positives = 72/84 (85%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 PGL+DCWG+EFE+LYE YE E + ++AQ LW AI+E+QVETG PYMLFKD+CNRKSN Sbjct: 363 PGLSDCWGEEFETLYEKYEAEGKGKKTIKAQQLWFAILESQVETGNPYMLFKDACNRKSN 422 Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252 Q+NLGTIK SNLCTEIVEYTS DE Sbjct: 423 QQNLGTIKSSNLCTEIVEYTSPDE 446 Score = 103 bits (246), Expect = 5e-21 Identities = 56/106 (52%), Positives = 70/106 (66%), Gaps = 22/106 (20%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDN----------------------KTYNFKKLKEVTKTITENLN 365 +AVCNLASIAL FV +N + ++ KL E+T+ +T NLN Sbjct: 447 TAVCNLASIALPRFVIENNPSSPTGRTETKKLVGSLKSKERFFDHSKLFEITRKVTRNLN 506 Query: 366 KIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEA 503 +IIDVNYYPV AK SN+RHRPIG+GVQGLAD FIL+ LP++SPEA Sbjct: 507 RIIDVNYYPVEAAKNSNMRHRPIGLGVQGLADVFILLGLPFDSPEA 552 >UniRef50_Q9SJ20 Cluster: Ribonucleoside-diphosphate reductase large subunit; n=17; cellular organisms|Rep: Ribonucleoside-diphosphate reductase large subunit - Arabidopsis thaliana (Mouse-ear cress) Length = 816 Score = 136 bits (330), Expect = 4e-31 Identities = 61/84 (72%), Positives = 69/84 (82%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 PGLADCWG EFE+LY YE+E + V+AQ LW I+ +QVETGTPYMLFKDSCNRKSN Sbjct: 357 PGLADCWGAEFETLYTKYEREGKAKKVVQAQQLWYEILTSQVETGTPYMLFKDSCNRKSN 416 Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252 Q+NLGTIK SNLCTEI+EYTS E Sbjct: 417 QQNLGTIKSSNLCTEIIEYTSPTE 440 Score = 121 bits (292), Expect = 1e-26 Identities = 72/144 (50%), Positives = 91/144 (63%), Gaps = 19/144 (13%) Frame = +3 Query: 252 SAVCNLASIALNMFVDD-------------------NKTYNFKKLKEVTKTITENLNKII 374 +AVCNLASIAL FV + N+ ++F+KL EVT T+T NLNKII Sbjct: 441 TAVCNLASIALPRFVREKGVPLDSHPPKLAGSLDSKNRYFDFEKLAEVTATVTVNLNKII 500 Query: 375 DVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALE 554 DVNYYPV AK SN+RHRPIGIGVQGLADAFIL+ +P++SPEA + AL+ Sbjct: 501 DVNYYPVETAKTSNMRHRPIGIGVQGLADAFILLGMPFDSPEAQQLNKDIFETIYYHALK 560 Query: 555 ASCELAAKVWECMIHTTDAPASRG 626 AS ELAA++ + +P S+G Sbjct: 561 ASTELAARLGPYETY-AGSPVSKG 583 >UniRef50_Q8JKL8 Cluster: Ribonucleoside-diphosphate reductase; n=1; Heliothis zea virus 1|Rep: Ribonucleoside-diphosphate reductase - Heliothis zea virus 1 Length = 939 Score = 133 bits (321), Expect = 4e-30 Identities = 58/84 (69%), Positives = 71/84 (84%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 PGL+DCWG+EFE+ Y YE+E R+V +V A+ LWKAI+ AQVETGTPY+L+KD+ NR SN Sbjct: 359 PGLSDCWGEEFEAKYTAYEQEGRYVRRVDARELWKAIVTAQVETGTPYILYKDTVNRNSN 418 Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252 Q++LGTIK SNLCTEIVEY S DE Sbjct: 419 QRHLGTIKGSNLCTEIVEYASPDE 442 Score = 97.5 bits (232), Expect = 3e-19 Identities = 55/127 (43%), Positives = 72/127 (56%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 +AVC LAS+ L FV+ K +N L + + +T NLNKIID YP+P A KSN +HRP Sbjct: 443 TAVCVLASVNLPKFVE-GKVFNLNLLAKTVRLVTRNLNKIIDNALYPIPSAAKSNFKHRP 501 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDA 611 IGIGVQG ADA +M + YE +N + AL SC+L A+V + Sbjct: 502 IGIGVQGYADALAMMGIAYEDSMQLN--RDIFETIYHAALTESCQL-ARVHGVYESYHGS 558 Query: 612 PASRGHI 632 P SRG + Sbjct: 559 PTSRGEL 565 >UniRef50_O12935 Cluster: Ribonucleoside-diphosphate reductase; n=2; Nucleopolyhedrovirus|Rep: Ribonucleoside-diphosphate reductase - Spodoptera exigua MNPV Length = 770 Score = 128 bits (308), Expect = 2e-28 Identities = 67/126 (53%), Positives = 88/126 (69%), Gaps = 1/126 (0%) Frame = +3 Query: 252 SAVCNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 +AVCNLASIA+N VD D KT+++ LK +TK I NLNKIIDVN+YP E+++SN +HR Sbjct: 425 TAVCNLASIAVNKCVDVDAKTFDYVLLKHLTKIIVRNLNKIIDVNHYPTAESERSNKKHR 484 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTD 608 PIG+G+QGLADAF+L+ + Y+S +A + ALEASCEL AK+ TD Sbjct: 485 PIGVGIQGLADAFVLLDIAYDSDDARFVNYSIAETIYFAALEASCEL-AKINGPYESYTD 543 Query: 609 APASRG 626 +P SRG Sbjct: 544 SPVSRG 549 Score = 104 bits (249), Expect = 2e-21 Identities = 48/84 (57%), Positives = 60/84 (71%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 P LAD +G +FE Y YE + QV+A+ L++ I+E VETG PYML+KD CN SN Sbjct: 341 PDLADKYGFDFEMRYCDYENAQVYERQVKARDLFRFIVETNVETGGPYMLYKDHCNNFSN 400 Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252 QKNLGTIKCSNLC EIV+Y ++E Sbjct: 401 QKNLGTIKCSNLCAEIVQYCDENE 424 >UniRef50_Q75BW6 Cluster: Ribonucleoside-diphosphate reductase; n=4; Saccharomycetaceae|Rep: Ribonucleoside-diphosphate reductase - Ashbya gossypii (Yeast) (Eremothecium gossypii) Length = 864 Score = 118 bits (283), Expect = 2e-25 Identities = 53/84 (63%), Positives = 66/84 (78%) Frame = +1 Query: 4 GLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQ 183 GL+DC+G+ FE LY YE+E +V+AQ LW+ I+ +Q ETG P+ML+KD+CN KSNQ Sbjct: 379 GLSDCYGEAFEQLYVRYERELEPYRRVKAQELWREILLSQTETGGPFMLYKDACNSKSNQ 438 Query: 184 KNLGTIKCSNLCTEIVEYTSDDEV 255 KNLGTIK SNLC EIVEY+S DEV Sbjct: 439 KNLGTIKSSNLCCEIVEYSSRDEV 462 Score = 111 bits (267), Expect = 2e-23 Identities = 58/129 (44%), Positives = 81/129 (62%), Gaps = 3/129 (2%) Frame = +3 Query: 255 AVCNLASIALNMFVD---DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRH 425 AVCNLAS+AL FV D T+++ +L V K +T NL+K ID+ YPVPEA++SN +H Sbjct: 463 AVCNLASVALPTFVSVTSDAITFDYARLHSVVKVMTRNLDKAIDIGDYPVPEAERSNKKH 522 Query: 426 RPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTT 605 RP+ +GVQGLAD F+LMR P+ EA + + A+E S ELAA+ + Sbjct: 523 RPLALGVQGLADVFMLMRFPFNGEEAAQMNREIFETIYHAAVETSIELAAE-YGVYASFV 581 Query: 606 DAPASRGHI 632 +PAS+G + Sbjct: 582 GSPASKGEL 590 >UniRef50_Q9QAL9 Cluster: Ribonucleoside-diphosphate reductase; n=2; Shrimp white spot syndrome virus|Rep: Ribonucleoside-diphosphate reductase - White spot syndrome virus (WSSV) Length = 848 Score = 109 bits (263), Expect = 5e-23 Identities = 58/131 (44%), Positives = 86/131 (65%), Gaps = 6/131 (4%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDN-----KTY-NFKKLKEVTKTITENLNKIIDVNYYPVPEAKKS 413 +AVCNLASIA+N FV + + Y +++++K V K +T NL+K+IDVN+Y V + + S Sbjct: 464 TAVCNLASIAVNKFVKYSPIPSLRPYVDYREMKRVVKIMTRNLDKVIDVNFYAVDKTRIS 523 Query: 414 NLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECM 593 N++ RP+G+GVQGLAD F +R+P+ES EA + + GALEASCE+A + E Sbjct: 524 NMKTRPMGLGVQGLADLFFKLRIPFESEEAALINKRIFETIYYGALEASCEIAKEKGETY 583 Query: 594 IHTTDAPASRG 626 +P S+G Sbjct: 584 ELFEGSPLSKG 594 Score = 105 bits (251), Expect = 1e-21 Identities = 47/84 (55%), Positives = 64/84 (76%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 PGL+D G+EF++LYE YE E + V+A+ L+ I A++ETGTPY+ FKD+ NRKSN Sbjct: 380 PGLSDVHGEEFKALYEKYEAEGKGKEVVKARALFDQINSARIETGTPYVCFKDTINRKSN 439 Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252 Q+N+G IK SNLCTEIV+Y+ +E Sbjct: 440 QENVGIIKSSNLCTEIVQYSDSEE 463 >UniRef50_Q7T6Y8 Cluster: Ribonucleoside-diphosphate reductase large chain; n=1; Acanthamoeba polyphaga mimivirus|Rep: Ribonucleoside-diphosphate reductase large chain - Mimivirus Length = 881 Score = 100 bits (240), Expect = 3e-20 Identities = 50/109 (45%), Positives = 74/109 (67%), Gaps = 3/109 (2%) Frame = +3 Query: 255 AVCNLASIALNMFV---DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRH 425 +VCNL+SI L FV D+ T+N++KL ++++ +T NLN IID+N+YP+ + + +NLR Sbjct: 508 SVCNLSSICLPRFVKIIDEVPTFNYQKLFKISRILTRNLNNIIDINFYPLDKTRITNLRD 567 Query: 426 RPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 RPIGIGVQGLAD F + + P++S A + K + GAL S +LA Sbjct: 568 RPIGIGVQGLADVFAMFKTPFDSEIARDLNRKIFETIYYGALTESNKLA 616 Score = 87.8 bits (208), Expect = 2e-16 Identities = 40/78 (51%), Positives = 53/78 (67%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 P L + +G EF Y YE E ++ Q+RA LW I+E+Q+ETG PY++FKD+ N KSN Sbjct: 423 PNLLNKYGDEFTKEYLKYESEGIYLKQIRAIDLWFKIMESQIETGVPYVMFKDAINDKSN 482 Query: 181 QKNLGTIKCSNLCTEIVE 234 Q N+G + SNLC EIVE Sbjct: 483 QINIGVVNGSNLCCEIVE 500 >UniRef50_Q6MLM3 Cluster: Ribonucleoside-diphosphate reductase alpha chain; n=14; Bacteria|Rep: Ribonucleoside-diphosphate reductase alpha chain - Bdellovibrio bacteriovorus Length = 801 Score = 95.9 bits (228), Expect = 8e-19 Identities = 46/109 (42%), Positives = 70/109 (64%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 +AVCNL S+ L V+ N +NF+KL +T + L++++D+N+YP+P A+ SN + RP Sbjct: 444 TAVCNLGSVNLARHVE-NGQFNFEKLARSVRTAVKYLDRVVDINFYPIPTAQDSNHKWRP 502 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 +G+GV GL DA LM+LP++S A + K + AL SCEL+ K Sbjct: 503 VGLGVMGLQDALFLMKLPFDSAAARDLSAKVQEEIYYNALVTSCELSEK 551 Score = 69.3 bits (162), Expect = 8e-11 Identities = 34/86 (39%), Positives = 51/86 (59%), Gaps = 2/86 (2%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 P D +G+EFE Y E++ ++ Q++A+ L+ +++ +TG +M FKD N K+N Sbjct: 358 PHFVDTYGEEFEKAYVEAEEKKLYIKQLKARDLYSRMMKTLAQTGNGWMTFKDHANLKAN 417 Query: 181 QKNL--GTIKCSNLCTEIVEYTSDDE 252 Q I SNLCTEI+E TSD E Sbjct: 418 QTGEAGNVIHLSNLCTEILEVTSDKE 443 >UniRef50_P26685 Cluster: Ribonucleoside-diphosphate reductase large chain; n=2; African swine fever virus|Rep: Ribonucleoside-diphosphate reductase large chain - African swine fever virus (isolate Malawi Lil 20/1) (ASFV) Length = 779 Score = 93.5 bits (222), Expect = 4e-18 Identities = 47/105 (44%), Positives = 66/105 (62%) Frame = +3 Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437 VCNLA++ L F+ ++ +Y+++ L E +TENL+ IID YYP ++SN+RHRPIG Sbjct: 439 VCNLAAVNLAAFIRES-SYDYRGLIEAAGNVTENLDNIIDNGYYPTEATRRSNMRHRPIG 497 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IGV GLAD F +++ + SPEAI GA+ S ELA Sbjct: 498 IGVFGLADVFASLKMKFGSPEAIAIDEAIHAALYYGAMRRSIELA 542 Score = 62.5 bits (145), Expect = 9e-09 Identities = 30/68 (44%), Positives = 41/68 (60%) Frame = +1 Query: 25 KEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIK 204 +EF+ LY Y E R+ A+ + K + V+ G PY+ FKD+ NRKSN ++GTI Sbjct: 358 REFKKLYYQYVAEKRYTGVTTAKEIIKEWFKTVVQVGNPYIGFKDAINRKSNLSHVGTIT 417 Query: 205 CSNLCTEI 228 SNLC EI Sbjct: 418 NSNLCIEI 425 >UniRef50_O41111 Cluster: Ribonucleoside-diphosphate reductase; n=2; Chlorovirus|Rep: Ribonucleoside-diphosphate reductase - Paramecium bursaria Chlorella virus 1 (PBCV-1) Length = 771 Score = 93.1 bits (221), Expect = 6e-18 Identities = 46/107 (42%), Positives = 71/107 (66%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 +AVC + S+ L +V ++K ++F L++ K + +NL++ IDV YP+ EA+ SN R RP Sbjct: 453 TAVCVIGSVVLKNYVKNDK-FDFDDLRKNVKILAKNLDRSIDVMSYPIKEAETSNKRRRP 511 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+GVQGL D F ++LP++SPEA + + + A+EAS ELA Sbjct: 512 IGVGVQGLQDVFFKLKLPFDSPEARDLNREIFEHIYYAAVEASVELA 558 Score = 89.0 bits (211), Expect = 1e-16 Identities = 39/84 (46%), Positives = 55/84 (65%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 PGL D +G E+ LY YE E + V+A+ +W ++ +ETG PY+ KD+ N+K+ Sbjct: 369 PGLTDAFGDEYAELYTRYEAEGKAKNVVKARDVWNTMVTTIIETGQPYVANKDTVNKKNM 428 Query: 181 QKNLGTIKCSNLCTEIVEYTSDDE 252 Q N GTI+ SNLC EI+EYTS +E Sbjct: 429 QSNAGTIRGSNLCIEILEYTSKEE 452 >UniRef50_A7IY07 Cluster: Putative uncharacterized protein B832R; n=1; Paramecium bursaria Chlorella virus NY2A|Rep: Putative uncharacterized protein B832R - Paramecium bursaria Chlorella virus NY2A (PBCV-NY2A) Length = 1103 Score = 88.2 bits (209), Expect = 2e-16 Identities = 45/107 (42%), Positives = 68/107 (63%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 +AVC + S+ L +V ++K ++F L++ K + +NL++ IDV YP+ EA+ SN RP Sbjct: 785 TAVCVIGSVVLKNYVKNDK-FDFDDLRKNVKILAKNLDRSIDVMAYPIKEAETSNKLRRP 843 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+GVQGL D F +R Y+SPEA + + + A+EAS ELA Sbjct: 844 IGVGVQGLQDVFFKLRFSYDSPEARDLNREIFEHIYYAAVEASVELA 890 Score = 76.2 bits (179), Expect = 7e-13 Identities = 33/73 (45%), Positives = 47/73 (64%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 PGL D +G E+ LYE YE E + V+A+ +W ++ +ETG PY+ KD+ N+K+ Sbjct: 365 PGLTDAFGDEYAELYERYEAEGKAKNVVKARDVWNTMVTTIIETGQPYVSNKDAVNKKNM 424 Query: 181 QKNLGTIKCSNLC 219 Q N GTI+ SNLC Sbjct: 425 QMNAGTIRGSNLC 437 >UniRef50_Q4J4L6 Cluster: Ribonucleoside-diphosphate reductase; n=3; cellular organisms|Rep: Ribonucleoside-diphosphate reductase - Azotobacter vinelandii AvOP Length = 1338 Score = 88.2 bits (209), Expect = 2e-16 Identities = 42/106 (39%), Positives = 64/106 (60%) Frame = +3 Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 AVCNL SI L ++D + + +KL KT L+ +ID+NYY V A+ +N RHRP+ Sbjct: 978 AVCNLGSINLVNHINDGRL-DTEKLSRTVKTAVRMLDNVIDINYYSVDTARNANFRHRPV 1036 Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 G+G+ G DA L + Y S AI ++ ++ + A++ASC+LA Sbjct: 1037 GLGIMGFQDALYLQHIAYGSEAAIAFADRSMEAISYYAIQASCDLA 1082 Score = 71.3 bits (167), Expect = 2e-11 Identities = 35/88 (39%), Positives = 51/88 (57%), Gaps = 5/88 (5%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRF-----VXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNR 171 L D G+ FE YE YE ++ + A+ LW+ ++ ETG P++ FKD CN Sbjct: 890 LHDLTGRAFEERYEYYEALTQYGKIKLFKTIAAKDLWRKMLSMLFETGHPWLTFKDPCNL 949 Query: 172 KSNQKNLGTIKCSNLCTEIVEYTSDDEV 255 +S Q+++G + SNLCTEI TSD E+ Sbjct: 950 RSPQQHVGVVHSSNLCTEITLNTSDSEI 977 >UniRef50_Q9HMU3 Cluster: Ribonucleoside-diphosphate reductase; n=1; Halobacterium salinarum|Rep: Ribonucleoside-diphosphate reductase - Halobacterium salinarium (Halobacterium halobium) Length = 804 Score = 85.0 bits (201), Expect = 2e-15 Identities = 41/109 (37%), Positives = 67/109 (61%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 +AVCNL S+ L +DD + ++L E +T L+ ++D+N+YP A++SN+RHRP Sbjct: 447 TAVCNLGSVNLARHLDDGDI-DREQLSETVETAMRMLDNVVDLNFYPTENAERSNMRHRP 505 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 +G+GV G DA MR+P S +A++ + + A+ AS +LAA+ Sbjct: 506 VGLGVMGFHDALQQMRVPMASDDALDRADALQEYVAYHAIGASADLAAE 554 Score = 65.3 bits (152), Expect = 1e-09 Identities = 35/88 (39%), Positives = 50/88 (56%), Gaps = 6/88 (6%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKE------NRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCN 168 L + +G +F Y YE RF +V A LW+ ++ ETG P++ FKD CN Sbjct: 360 LYELYGSDFAERYREYEAMADDGDIQRF-ERVDATDLWRTMLTRLFETGHPWLTFKDPCN 418 Query: 169 RKSNQKNLGTIKCSNLCTEIVEYTSDDE 252 +S Q + GT++ SNLCTEI TS++E Sbjct: 419 VRSPQDHAGTVRSSNLCTEITLNTSEEE 446 >UniRef50_Q3AEA3 Cluster: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent, intein-containing; n=2; Bacteria|Rep: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent, intein-containing - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 1101 Score = 83.8 bits (198), Expect = 4e-15 Identities = 42/104 (40%), Positives = 63/104 (60%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL SI L V D + +++ L++ K L+ +IDVN+YP+PE +K + R IG+ Sbjct: 627 CNLGSINLANMVKDGEI-DWEHLEKTVKLAVRFLDNVIDVNHYPLPEIEKMTKKTRKIGL 685 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 GV G AD I + +PY+S EA+N +K ++ + EAS ELA Sbjct: 686 GVMGFADMLIKLNIPYDSEEALNLADKVMEFINKKSKEASAELA 729 >UniRef50_O84834 Cluster: Ribonucleoside-diphosphate reductase subunit alpha; n=29; Bacteria|Rep: Ribonucleoside-diphosphate reductase subunit alpha - Chlamydia trachomatis Length = 1047 Score = 83.4 bits (197), Expect = 5e-15 Identities = 41/89 (46%), Positives = 56/89 (62%), Gaps = 5/89 (5%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEK-----ENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSC 165 PGL D +G+EFE LYE YE+ E R +V A+ LW+ ++ ETG P+M FKD Sbjct: 595 PGLHDAYGEEFERLYEEYERKVDTGEIRLFKKVEAEDLWRKMLSMLFETGHPWMTFKDPS 654 Query: 166 NRKSNQKNLGTIKCSNLCTEIVEYTSDDE 252 N +S Q + G ++CSNLCTEI+ S+ E Sbjct: 655 NIRSAQDHKGVVRCSNLCTEILLNCSETE 683 Score = 77.4 bits (182), Expect = 3e-13 Identities = 41/107 (38%), Positives = 61/107 (57%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 +AVCNL SI L + + + +KL E L+ +ID+N+YP EAK++N HR Sbjct: 684 TAVCNLGSINLVQHIVGDGL-DEEKLSETISIAVRMLDNVIDINFYPTKEAKEANFAHRA 742 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+GV G DA + + Y S EA+ + +L + A++ASC LA Sbjct: 743 IGLGVMGFQDALYKLDISYASQEAVEFADYSSELISYYAIQASCLLA 789 >UniRef50_Q67KQ2 Cluster: Ribonucleoside-diphosphate reductase; n=1; Symbiobacterium thermophilum|Rep: Ribonucleoside-diphosphate reductase - Symbiobacterium thermophilum Length = 776 Score = 78.2 bits (184), Expect = 2e-13 Identities = 43/108 (39%), Positives = 61/108 (56%), Gaps = 4/108 (3%) Frame = +3 Query: 261 CNLASIALNMFVD----DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 CNL SI L FV D ++++L EV +T T L+ +ID N YP+P+ + LR R Sbjct: 282 CNLGSINLANFVKNPYTDRAEVDWERLGEVARTATRFLDNVIDANKYPLPQIAEKALRDR 341 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+G+ G A+ + M LPY+S EA+ N+ + ALE S LA Sbjct: 342 RIGLGIMGWAEMLVQMGLPYDSEEAVALGNRVMTFIKQKALEESMALA 389 Score = 36.3 bits (80), Expect = 0.71 Identities = 18/62 (29%), Positives = 34/62 (54%), Gaps = 1/62 (1%) Frame = +1 Query: 43 YETYEKENRFVX-QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219 YE N V ++ A+++W ++E +TG P ++F D NR++ ++ I+ +N C Sbjct: 212 YELINPRNGEVTGKLSAKLVWDKLVENAWKTGEPGIVFIDRINRRNPNNHVEVIEATNPC 271 Query: 220 TE 225 E Sbjct: 272 GE 273 >UniRef50_A2XAQ8 Cluster: Ribonucleoside-diphosphate reductase; n=4; Oryza sativa|Rep: Ribonucleoside-diphosphate reductase - Oryza sativa subsp. indica (Rice) Length = 676 Score = 78.2 bits (184), Expect = 2e-13 Identities = 32/52 (61%), Positives = 41/52 (78%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFK 156 PGLADCWG EF++LY+ YE+E + V AQ LW I++AQ+ETGTPYML+K Sbjct: 357 PGLADCWGDEFQNLYKKYEREGKAKKVVSAQALWFDILKAQIETGTPYMLYK 408 Score = 34.7 bits (76), Expect = 2.2 Identities = 16/35 (45%), Positives = 22/35 (62%) Frame = +2 Query: 509 LNQQIFETIYYGSTRGKL*TSSKSMGVYDTYDGCP 613 LN+ IFETIYY + + ++K G Y+TY G P Sbjct: 412 LNKDIFETIYYHALKASAEIAAKE-GPYETYSGSP 445 >UniRef50_Q39JT6 Cluster: Ribonucleoside-diphosphate reductase; n=86; Bacteria|Rep: Ribonucleoside-diphosphate reductase - Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 / R18194)) Length = 998 Score = 77.8 bits (183), Expect = 2e-13 Identities = 41/110 (37%), Positives = 60/110 (54%), Gaps = 4/110 (3%) Frame = +3 Query: 255 AVCNLASIALNMFV----DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422 AVCNL S+ L + D + + KLK L+ +ID+NYY V +A+ SNL+ Sbjct: 603 AVCNLGSVNLVAHLVKQADGSFALDHDKLKRTISVAMRMLDNVIDINYYAVAKARNSNLK 662 Query: 423 HRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 HRP+G+G+ G D L+R PY S A+ ++ ++ A AS ELA Sbjct: 663 HRPVGMGIMGFQDCLHLLRTPYASEAAVAFADRSMEAVCYYAYHASTELA 712 Score = 74.1 bits (174), Expect = 3e-12 Identities = 37/90 (41%), Positives = 53/90 (58%), Gaps = 5/90 (5%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEK-----ENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSC 165 P L D +G EFE+ Y YE E + ++ A LW+ ++ ETG P++ FKD C Sbjct: 513 PDLHDKFGAEFEAAYTAYEDKVARGEIKLFKKIPAAQLWRKMLGMLFETGHPWITFKDPC 572 Query: 166 NRKSNQKNLGTIKCSNLCTEIVEYTSDDEV 255 N +S Q+++G + SNLCTEI TSD E+ Sbjct: 573 NVRSPQQHVGVVHSSNLCTEITLNTSDSEI 602 >UniRef50_Q3E5I1 Cluster: Ribonucleoside-diphosphate reductase; n=2; Chloroflexus|Rep: Ribonucleoside-diphosphate reductase - Chloroflexus aurantiacus J-10-fl Length = 822 Score = 76.6 bits (180), Expect = 5e-13 Identities = 44/127 (34%), Positives = 69/127 (54%), Gaps = 5/127 (3%) Frame = +3 Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437 VCNL SI L FV D T +++ L++V T L+ +ID N+YP+ + + + R R IG Sbjct: 312 VCNLGSINLGKFVTDAGTIDWESLRDVVHESTRFLDNVIDANHYPLEQITQLSQRIRRIG 371 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK-----VWECMIHT 602 +GV G AD + + +PY S +AI+ + ++ + AS +LA + WE I Sbjct: 372 LGVMGWADMLVRLGIPYNSAQAIDLARQVMRFIDEESKVASEQLARERGPFPEWEYSIWG 431 Query: 603 TDAPASR 623 DA +R Sbjct: 432 PDATCAR 438 >UniRef50_P74911 Cluster: Ribonucleoside-diphosphate reductase; n=5; Thermoplasmatales|Rep: Ribonucleoside-diphosphate reductase - Thermoplasma acidophilum Length = 857 Score = 75.8 bits (178), Expect = 1e-12 Identities = 41/104 (39%), Positives = 57/104 (54%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL SI L+ +V D K +F +L+E T T L+ +ID N +PV + KK R IG+ Sbjct: 445 CNLGSINLSKYVVDGKKIDFDRLRETVWTATRFLDDVIDANKFPVEQIKKVTRMTRKIGL 504 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 GV G AD I + +PY S EA+ K + + +AS LA Sbjct: 505 GVMGFADMLIKLEIPYNSWEALEIGEKVMSFINDESHKASQALA 548 Score = 46.4 bits (105), Expect = 7e-04 Identities = 19/56 (33%), Positives = 35/56 (62%) Frame = +1 Query: 58 KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 + + + +++A+ +W AII+ +T P ++F D NRK+ KN+G I+ +N C E Sbjct: 381 RTKKIMKRIKAREIWDAIIDQAWKTADPGLIFLDEINRKNPVKNVGDIESTNPCGE 436 >UniRef50_UPI0000F5175D Cluster: hypothetical protein Faci_03000650; n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical protein Faci_03000650 - Ferroplasma acidarmanus fer1 Length = 1136 Score = 75.4 bits (177), Expect = 1e-12 Identities = 38/106 (35%), Positives = 58/106 (54%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL SI L FV+D K +N+++ +E T L ++D N +PV K + R IG+ Sbjct: 815 CNLGSINLAKFVEDGK-FNYERYRETIDVATRFLENVVDANKFPVESIKNMTRKTRKIGL 873 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 G+ G ADA I++ +PY S EA+ +K + S +LAA+ Sbjct: 874 GIMGFADALIMLGIPYNSNEALEFAENVMKTLNDESHMESQKLAAE 919 Score = 44.0 bits (99), Expect = 0.004 Identities = 19/54 (35%), Positives = 32/54 (59%) Frame = +1 Query: 58 KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219 ++ + +V+A LW +II+ T P M+F D N+K+ KN+G I+ +N C Sbjct: 385 RDGKVTGRVKATTLWNSIIDHAWLTADPGMIFLDEINKKNPVKNIGYIESTNPC 438 >UniRef50_Q8R7R2 Cluster: Ribonucleoside-diphosphate reductase; n=1; Thermoanaerobacter tengcongensis|Rep: Ribonucleoside-diphosphate reductase - Thermoanaerobacter tengcongensis Length = 691 Score = 74.5 bits (175), Expect = 2e-12 Identities = 40/105 (38%), Positives = 62/105 (59%) Frame = +3 Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437 VCNL +I L FV++ K NF++L+E K L+ ++D+ Y +P+ K+ + R +G Sbjct: 272 VCNLGAINLVAFVENGKI-NFEELEETVKIAVRFLDNVLDLGAYVLPQNKEMAQKLRRVG 330 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 +G+ GLADA ILM L Y S E++ + ++ A AS ELA Sbjct: 331 LGLMGLADALILMNLRYGSEESLKATEEIVRRIRDAAYRASVELA 375 >UniRef50_Q6A5Y5 Cluster: Ribonucleoside-diphosphate reductase alpha chain; n=6; Actinobacteria (class)|Rep: Ribonucleoside-diphosphate reductase alpha chain - Propionibacterium acnes Length = 856 Score = 74.5 bits (175), Expect = 2e-12 Identities = 36/112 (32%), Positives = 68/112 (60%), Gaps = 3/112 (2%) Frame = +3 Query: 252 SAVCNLASIALNMFVDD---NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422 +AVCNLAS+ L + + ++ +L T+ +L+ ++D+ VP+A++SN Sbjct: 465 TAVCNLASVNLAAHLAGPRGKRRLDWDQLAATTRLAVRHLDNLVDITASAVPQAQRSNEE 524 Query: 423 HRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 +R IG+GV GL D +R+PY+SP+A +++ ++ + A++ S +LAA+ Sbjct: 525 NRAIGLGVMGLTDMLEQIRVPYDSPDACEIVDRVVEFISWHAIDTSADLAAE 576 Score = 47.6 bits (108), Expect = 3e-04 Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 6/82 (7%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKE------NRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDS 162 P L + G +F Y Y ++ RF + A+ ++AI+ + T P++ +KDS Sbjct: 376 PDLTELTGSDFSKRYAQYVEQAEAGKIKRF-RRTTAREQFRAILVSLQTTSHPWLTWKDS 434 Query: 163 CNRKSNQKNLGTIKCSNLCTEI 228 N ++ N GTI SNLCTEI Sbjct: 435 INTRALNSNTGTIHSSNLCTEI 456 >UniRef50_A4L245 Cluster: Ribonucleotide reductase large subunit; n=1; Gryllus bimaculatus nudivirus|Rep: Ribonucleotide reductase large subunit - Gryllus bimaculatus nudivirus Length = 683 Score = 73.7 bits (173), Expect = 4e-12 Identities = 32/77 (41%), Positives = 52/77 (67%) Frame = +1 Query: 25 KEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIK 204 KEFE LYET+ E ++ ++ ++K II+ + TG+PY++F D+ N+ +N K+LG IK Sbjct: 294 KEFEELYETFVSEQKYTNMYESRKIFKDIIKNILMTGSPYIIFIDNVNKFNNIKHLGKIK 353 Query: 205 CSNLCTEIVEYTSDDEV 255 NLC+EI Y ++D + Sbjct: 354 TLNLCSEITNYCNEDVI 370 >UniRef50_Q8TQ86 Cluster: Ribonucleoside-diphosphate reductase; n=4; Methanomicrobia|Rep: Ribonucleoside-diphosphate reductase - Methanosarcina acetivorans Length = 558 Score = 73.3 bits (172), Expect = 5e-12 Identities = 39/106 (36%), Positives = 59/106 (55%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL S+ L++FV D K N+ L+E L+ ID+N YPVPE ++ + R IG+ Sbjct: 270 CNLGSLNLSLFVADGKI-NWDFLRETAGKAVRFLDNEIDINVYPVPEIAEATRKTRKIGL 328 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 GV G D + + L Y+S EA+ K ++ A+ S +LAA+ Sbjct: 329 GVMGFHDMLLKLGLSYDSTEAVELAEKLMEQINWAAVRESRKLAAE 374 >UniRef50_Q6R7H4 Cluster: Ribonucleoside-diphosphate reductase; n=1; Ostreid herpesvirus 1|Rep: Ribonucleoside-diphosphate reductase - Ostreid herpesvirus 1 Length = 835 Score = 72.5 bits (170), Expect = 9e-12 Identities = 36/85 (42%), Positives = 51/85 (60%), Gaps = 1/85 (1%) Frame = +1 Query: 4 GLADCWGKEFESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 GL + +G++F Y +E + V A+ L+ I TG PY+LFKD+ N +SN Sbjct: 377 GLEELYGEKFVRAYRAHEANPKIKRTTVSARKLFSDIANMMWSTGEPYILFKDAVNERSN 436 Query: 181 QKNLGTIKCSNLCTEIVEYTSDDEV 255 K+LGTIK SNLC EIV+Y +E+ Sbjct: 437 HKHLGTIKNSNLCCEIVQYCDTNEI 461 Score = 46.8 bits (106), Expect(2) = 6e-07 Identities = 22/54 (40%), Positives = 33/54 (61%) Frame = +3 Query: 411 SNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 SNL+HRP GIG+QGL D F+ +++PY+S A + GA+ S ++A Sbjct: 543 SNLKHRPQGIGMQGLHDVFMKLKIPYDSEMAFRLAALIQEAIYYGAVRESVKIA 596 Score = 29.5 bits (63), Expect(2) = 6e-07 Identities = 14/46 (30%), Positives = 26/46 (56%), Gaps = 1/46 (2%) Frame = +3 Query: 255 AVCNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYY 389 AVCNLA+I ++ FV+ + +F+ + + + +N +ID Y Sbjct: 462 AVCNLATICVSNFVNVETGEIDFEGIADAAGVACKGINNLIDKQNY 507 >UniRef50_Q6UDJ2 Cluster: Ribonucleoside-diphosphate reductase; n=3; Alphaherpesvirinae|Rep: Ribonucleoside-diphosphate reductase - Psittacid herpesvirus 1 Length = 811 Score = 71.3 bits (167), Expect = 2e-11 Identities = 36/84 (42%), Positives = 53/84 (63%), Gaps = 1/84 (1%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186 L+D +G+EFE YE E++N + A+ + A+I++ V TGTP+++FK + NR Sbjct: 381 LSDLYGEEFEKEYELLERKNVGIATYPARDVMFALIKSAVSTGTPFVMFKHAVNRNYFFD 440 Query: 187 NLG-TIKCSNLCTEIVEYTSDDEV 255 G +KCSNLCTEIV T D+ V Sbjct: 441 MAGRAMKCSNLCTEIVHMTDDESV 464 Score = 48.8 bits (111), Expect = 1e-04 Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 9/113 (7%) Frame = +3 Query: 258 VCNLASIALNMFVDDNK---------TYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKK 410 VCNL S+ L FV T+++ ++ T +N ++ ++ P+ A Sbjct: 466 VCNLTSLNLAAFVTRRNALPGTPPIGTFDYSSFRDACAVATVFINALMSLSNLPIKRATT 525 Query: 411 SNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCEL 569 N R R IGIGVQG A +L +S EA K + + + SC + Sbjct: 526 GNERLRSIGIGVQGFHTACLLQGFGLDSVEACRFNGKLFEALALTTFQTSCRI 578 >UniRef50_Q91ES8 Cluster: ORF127 RR1; n=1; Cydia pomonella granulovirus|Rep: ORF127 RR1 - Cydia pomonella granulosis virus (CpGV) (Cydia pomonellagranulovirus) Length = 624 Score = 70.9 bits (166), Expect = 3e-11 Identities = 30/87 (34%), Positives = 49/87 (56%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186 L DC+G+E+E LYE + + V LW I+ G PY++++D+ N+ +NQ+ Sbjct: 218 LNDCYGEEYERLYEEMVRRGIQIKSVNVWELWGEIVNCLATNGYPYIVWRDTVNKYNNQQ 277 Query: 187 NLGTIKCSNLCTEIVEYTSDDEVQYAT 267 LG +K NLC E+ ++ +D V T Sbjct: 278 ALGVVKTLNLCAEVCQHATDSTVDTNT 304 >UniRef50_A2DI13 Cluster: Ribonucleoside-diphosphate reductase; n=1; Trichomonas vaginalis G3|Rep: Ribonucleoside-diphosphate reductase - Trichomonas vaginalis G3 Length = 614 Score = 70.9 bits (166), Expect = 3e-11 Identities = 38/103 (36%), Positives = 56/103 (54%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL +I L FV D K +FK L+EVT+T L+ ++ + +PV +R IG+ Sbjct: 310 CNLGAINLEKFVVDGKI-DFKHLEEVTRTAIRMLDNVVSLTKFPVQRVTDMFTNNRRIGL 368 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCEL 569 G+ GLAD LM+LPY+S E + +K A++ S L Sbjct: 369 GIMGLADLLFLMKLPYDSEEGRACAEEVMKCVQDSAIDESKRL 411 >UniRef50_A6QCU9 Cluster: Ribonucleoside-diphosphate reductase, alpha subunit; n=15; Epsilonproteobacteria|Rep: Ribonucleoside-diphosphate reductase, alpha subunit - Sulfurovum sp. (strain NBC37-1) Length = 789 Score = 69.7 bits (163), Expect = 6e-11 Identities = 32/81 (39%), Positives = 51/81 (62%), Gaps = 2/81 (2%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQ--VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 L + +G+EFE Y E + + + + A+ LWK I+ + ETG P++ FKD+ NR + Sbjct: 355 LTELYGEEFEKRYVELEHSDADITREVISAKGLWKEILRSYFETGNPFLTFKDAANRANP 414 Query: 181 QKNLGTIKCSNLCTEIVEYTS 243 K++G I+ SNLCTEI + T+ Sbjct: 415 NKHVGIIRSSNLCTEIFQNTA 435 Score = 60.5 bits (140), Expect = 4e-08 Identities = 35/107 (32%), Positives = 60/107 (56%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 +AVCNLASI L+ K + + + V T L+ +ID+N+YP+ + K++N + R Sbjct: 495 TAVCNLASINLS------KIHTKEDIARVVPTAVRMLDNVIDLNFYPLAKVKRTNEKSRS 548 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+GV G A ++ + S + I++ ++ + A+EAS LA Sbjct: 549 IGLGVMGEAQMLAENQIAWGSHDHFTKIDEVMESVSYYAIEASSNLA 595 >UniRef50_O26748 Cluster: Ribonucleoside-diphosphate reductase; n=1; Methanothermobacter thermautotrophicus str. Delta H|Rep: Ribonucleoside-diphosphate reductase - Methanobacterium thermoautotrophicum Length = 703 Score = 69.7 bits (163), Expect = 6e-11 Identities = 37/104 (35%), Positives = 56/104 (53%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL S+ L++ V + N++KL+ L+ +IDVN YP+ ++ LR R IG+ Sbjct: 411 CNLGSVNLSLMVGPSGI-NWEKLRRTIHVAVHFLDNVIDVNSYPLRPVEEMTLRTRKIGL 469 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 GV G AD I + +PY S A+ + + + A AS ELA Sbjct: 470 GVMGFADMLIKLGIPYNSVAALEVAGRVMSFISSEARRASMELA 513 Score = 39.9 bits (89), Expect = 0.058 Identities = 19/54 (35%), Positives = 30/54 (55%) Frame = +1 Query: 58 KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219 + V V ++V+ K I+EA +G P +LF+D NR + LG I+ +N C Sbjct: 213 RNGEVVDSVESRVILKRIVEAAWRSGDPGILFEDRINRYNPTPQLGRIEATNPC 266 >UniRef50_Q67SN6 Cluster: Ribonucleoside-diphosphate reductase; n=2; Firmicutes|Rep: Ribonucleoside-diphosphate reductase - Symbiobacterium thermophilum Length = 782 Score = 68.9 bits (161), Expect = 1e-10 Identities = 38/107 (35%), Positives = 62/107 (57%) Frame = +3 Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437 VCNLASI L+ K + +K+ EV L+ +ID+N+YPVP+AK +N ++R IG Sbjct: 510 VCNLASINLS------KVHTEEKIAEVVPLAIRMLDNVIDLNFYPVPQAKITNKKYRAIG 563 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 +GV G + + +ES + + ++ +L A++ S ELAA+ Sbjct: 564 LGVHGYHQMLAELGIHWESEDHLRKADEVFELLNYYAVKTSIELAAE 610 Score = 67.3 bits (157), Expect = 3e-10 Identities = 33/83 (39%), Positives = 50/83 (60%), Gaps = 4/83 (4%) Frame = +1 Query: 7 LADCWGKEFESLY----ETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRK 174 L D WG+E+E Y E + VRA+ + KA++++Q ETG P++ F+D+ NR Sbjct: 403 LEDAWGEEWERRYRLCVEAAHADKLDATVVRARQVAKAMLKSQYETGGPFLFFRDTVNRL 462 Query: 175 SNQKNLGTIKCSNLCTEIVEYTS 243 + K+ G + CSNLCTEI + S Sbjct: 463 NPNKHAGMVYCSNLCTEIAQNQS 485 >UniRef50_A0RYG3 Cluster: Ribonucleoside-diphosphate reductase; n=3; Crenarchaeota|Rep: Ribonucleoside-diphosphate reductase - Cenarchaeum symbiosum Length = 881 Score = 68.9 bits (161), Expect = 1e-10 Identities = 38/108 (35%), Positives = 60/108 (55%), Gaps = 4/108 (3%) Frame = +3 Query: 261 CNLASIALNMFV----DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 CNL SI L V D +++++ +E+ + T L+ +IDVN YPV E +++ R Sbjct: 479 CNLGSINLARLVKRKADGEFEFDWQRYEEMIRKTTRFLDNVIDVNLYPVKEIDRASKESR 538 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+GV G+AD +R+PY S E + +K + T ++E S LA Sbjct: 539 RIGLGVMGVADLLYKLRIPYNSKEGYDLQSKLAEALTYYSMEESVALA 586 >UniRef50_P55982 Cluster: Ribonucleoside-diphosphate reductase subunit alpha; n=11; Campylobacterales|Rep: Ribonucleoside-diphosphate reductase subunit alpha - Helicobacter pylori (Campylobacter pylori) Length = 788 Score = 68.9 bits (161), Expect = 1e-10 Identities = 31/80 (38%), Positives = 50/80 (62%), Gaps = 1/80 (1%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQ 183 L + +G++FE Y YEK+ + + + + A+ LWK I+ E G P++ FKD+ NR + Sbjct: 355 LTELYGQDFEKRYLEYEKDPKIIKEYINAKDLWKKILMNYFEAGLPFLAFKDNANRCNPN 414 Query: 184 KNLGTIKCSNLCTEIVEYTS 243 + G I+ SNLCTEI + T+ Sbjct: 415 AHAGIIRSSNLCTEIFQNTA 434 Score = 59.3 bits (137), Expect = 9e-08 Identities = 35/107 (32%), Positives = 59/107 (55%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 +AVCNLASI L+ K + +K V + L+ +ID+N+YP + K +NL++R Sbjct: 494 TAVCNLASINLS------KINTEEDIKRVVPIMVRLLDNVIDLNFYPNRKVKATNLQNRA 547 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+GV G A ++ + S E + I+ ++ + A++ S LA Sbjct: 548 IGLGVMGEAQMLAEHQIAWGSKEHLEKIDALMEQISYHAIDTSANLA 594 >UniRef50_Q647Z9 Cluster: Ribonucleoside-diphosphate reductase; n=3; cellular organisms|Rep: Ribonucleoside-diphosphate reductase - uncultured archaeon GZfos9C4 Length = 914 Score = 68.5 bits (160), Expect = 1e-10 Identities = 36/104 (34%), Positives = 60/104 (57%), Gaps = 1/104 (0%) Frame = +3 Query: 261 CNLASIALNMFVDDNK-TYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437 CNL SI ++ FV ++++L+EV + L+ +IDVN YP+PE +K +R IG Sbjct: 608 CNLGSINVSKFVKSGDGEIDWERLREVICISVKFLDDVIDVNRYPLPEIEKMTKANRKIG 667 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCEL 569 +G+ G A+ I + + Y+S +A++ K ++ T A S EL Sbjct: 668 LGIMGFAELLIKLGIAYDSKDALSTGEKLMQFITNEARRCSTEL 711 Score = 33.1 bits (72), Expect = 6.6 Identities = 14/49 (28%), Positives = 29/49 (59%) Frame = +1 Query: 73 VXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219 V +++A+ ++ I+ +TG P ++F D NR++ +G I+ +N C Sbjct: 242 VKRIKAREVFNEIVTYAWKTGDPGIVFMDEINRRNTIPAVGKIEATNPC 290 >UniRef50_Q6QXF6 Cluster: ORF37; n=4; Baculoviridae|Rep: ORF37 - Agrotis segetum granulosis virus (AsGV) (Agrotis segetumgranulovirus) Length = 615 Score = 68.1 bits (159), Expect = 2e-10 Identities = 31/87 (35%), Positives = 51/87 (58%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186 L DC+G+E+ESLY ++ +V ++ A + +I E G PY++++D N +N + Sbjct: 226 LNDCYGEEYESLYWRMVEKKLYVKKMYATQVLGELISCLTENGFPYVVWRDHVNMFNNHR 285 Query: 187 NLGTIKCSNLCTEIVEYTSDDEVQYAT 267 +LGTI+ NLCTEI ++ D T Sbjct: 286 DLGTIQTLNLCTEICQHAGSDSSSMCT 312 >UniRef50_Q6AJC4 Cluster: Ribonucleoside-diphosphate reductase; n=1; Desulfotalea psychrophila|Rep: Ribonucleoside-diphosphate reductase - Desulfotalea psychrophila Length = 785 Score = 68.1 bits (159), Expect = 2e-10 Identities = 32/80 (40%), Positives = 50/80 (62%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL SI L FV +++ ++ +L ++ KT T L+ +ID N +P+PE + L+ R IG+ Sbjct: 346 CNLGSINLGNFVKNDEV-DYSRLGQIVKTATCFLDNVIDCNVFPIPEIGEMTLKTRKIGL 404 Query: 441 GVQGLADAFILMRLPYESPE 500 G+ GL D I + +PY S E Sbjct: 405 GIMGLHDLLIQLAIPYGSEE 424 >UniRef50_Q6VMN2 Cluster: Ribonucleoside-diphosphate reductase; n=10; Tortoise herpesvirus|Rep: Ribonucleoside-diphosphate reductase - Tortoise herpesvirus Length = 796 Score = 67.3 bits (157), Expect = 3e-10 Identities = 35/82 (42%), Positives = 47/82 (57%), Gaps = 1/82 (1%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186 LA +GKEFE Y E V Q+ + L II + + TG+P+++FKDSCNR Sbjct: 355 LAKLYGKEFEDEYHRLETAGMAVRQMPIKELLFKIIRSAIMTGSPFIMFKDSCNRHYYMD 414 Query: 187 NLG-TIKCSNLCTEIVEYTSDD 249 G I+ SNLCTEI+ +T D Sbjct: 415 TQGQAIRGSNLCTEIIHHTEPD 436 Score = 39.5 bits (88), Expect = 0.076 Identities = 25/89 (28%), Positives = 42/89 (47%) Frame = +3 Query: 303 NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRL 482 ++ +NF+KL E T +N +ID + +P + + R +GIG QGL ++ Sbjct: 481 HRYFNFEKLTEAVTAATIFINVMIDRSVHPTTKTQNGAKNFRSMGIGFQGLNTLCWILGE 540 Query: 483 PYESPEAIN*INKYLKLFTMGALEASCEL 569 +P+A + + A EAS EL Sbjct: 541 TLVTPKARKLGKTICEAMYLSAAEASNEL 569 >UniRef50_A5FSC1 Cluster: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; n=36; cellular organisms|Rep: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent - Dehalococcoides sp. BAV1 Length = 866 Score = 66.9 bits (156), Expect = 4e-10 Identities = 37/109 (33%), Positives = 58/109 (53%), Gaps = 3/109 (2%) Frame = +3 Query: 261 CNLASIALNMFVD---DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 CNL SI L+ V T ++KKL V K+ L+ +IDVN +P+P+ ++ + R Sbjct: 406 CNLGSINLSRMVTVSGGQNTVDYKKLSRVIKSAVRFLDNVIDVNKFPLPQIEEMTKKSRK 465 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 IG+GV G AD + + +PY S +I + + A + S ELA + Sbjct: 466 IGLGVMGFADMLLELGVPYNSENSIKLAEEIMCFVNDEAHKFSSELAVE 514 >UniRef50_Q9UYA0 Cluster: Ribonucleoside-diphosphate reductase; n=2; Pyrococcus|Rep: Ribonucleoside-diphosphate reductase - Pyrococcus abyssi Length = 2122 Score = 66.9 bits (156), Expect = 4e-10 Identities = 42/110 (38%), Positives = 60/110 (54%), Gaps = 4/110 (3%) Frame = +3 Query: 261 CNLASIALNMFV--DDN-KTY-NFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 CNLASI L FV D+N K Y ++ + V + + + L+ IDVN +P+PE + R Sbjct: 1691 CNLASINLAKFVKYDENGKPYFDWDEYAYVIQKVAKYLDNSIDVNKFPLPEIDYNTKLTR 1750 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 IG+G+ GLADA + +PY S E + K + T A + S E A K Sbjct: 1751 RIGVGMMGLADALFKLGIPYNSEEGFKFMRKVTEYLTFYAYKYSIEAAKK 1800 >UniRef50_P95484 Cluster: Ribonucleoside-diphosphate reductase; n=2; Thermococcaceae|Rep: Ribonucleoside-diphosphate reductase - Pyrococcus furiosus Length = 1740 Score = 66.9 bits (156), Expect = 4e-10 Identities = 42/110 (38%), Positives = 60/110 (54%), Gaps = 4/110 (3%) Frame = +3 Query: 261 CNLASIALNMFV--DDN-KTY-NFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 CNLASI L FV D+N K Y ++ + V + + + L+ IDVN +P+PE + R Sbjct: 1308 CNLASINLAKFVKYDENGKPYFDWDEYAYVIQKVAKYLDNSIDVNKFPLPEIDYNTKLTR 1367 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 IG+G+ GLADA + +PY S E + K + T A + S E A K Sbjct: 1368 RIGVGMMGLADALFKLGIPYNSEEGFKFMRKVTEYLTFYAYKYSVEAAKK 1417 >UniRef50_A3QTY4 Cluster: Ribonucleotide reductase large subunit; n=1; Oryctes rhinoceros virus|Rep: Ribonucleotide reductase large subunit - Oryctes rhinoceros virus Length = 737 Score = 65.7 bits (153), Expect = 1e-09 Identities = 29/79 (36%), Positives = 47/79 (59%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186 L + G E++ +Y+ + + N + +V + L ++ ETG+PY+++ D+ NR SN K Sbjct: 328 LCEFTGDEYKRMYKRFVEANLYTNKVSSSALMDDLVTCISETGSPYVVWSDNVNRFSNHK 387 Query: 187 NLGTIKCSNLCTEIVEYTS 243 +LG IK NLC EI Y S Sbjct: 388 HLGKIKTLNLCAEIANYAS 406 >UniRef50_Q8VKI9 Cluster: Ribonucleoside-diphosphate reductase; n=13; Mycobacterium|Rep: Ribonucleoside-diphosphate reductase - Mycobacterium tuberculosis Length = 735 Score = 65.3 bits (152), Expect = 1e-09 Identities = 36/104 (34%), Positives = 56/104 (53%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL SI L + D + ++ +L+EV L+ +IDV+ YP PE ++ R IG+ Sbjct: 431 CNLGSINLARMLADGRV-DWDRLEEVAGVAVRFLDDVIDVSRYPFPELGEAARATRKIGL 489 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 GV GLA+ + +PY+S EA+ + ++ A AS LA Sbjct: 490 GVMGLAELLAALGIPYDSEEAVRLATRLMRRIQQAAHTASRRLA 533 Score = 32.7 bits (71), Expect = 8.8 Identities = 17/57 (29%), Positives = 30/57 (52%) Frame = +1 Query: 58 KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEI 228 + + V ++ A L+ AI +A G P ++F D+ NR + G I+ +N C E+ Sbjct: 367 RTGKIVARMPAAELFDAICKAAHAGGDPGLVFLDTINRANPVPGRGRIEATNPCGEV 423 >UniRef50_O83972 Cluster: Ribonucleoside-diphosphate reductase subunit alpha; n=13; Bacteria|Rep: Ribonucleoside-diphosphate reductase subunit alpha - Treponema pallidum Length = 845 Score = 65.3 bits (152), Expect = 1e-09 Identities = 37/106 (34%), Positives = 59/106 (55%), Gaps = 1/106 (0%) Frame = +3 Query: 258 VCNLASIAL-NMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 VCNLAS+ L N+ + D+K +L+EV + L+ +ID+ YYPVP A+ +N +R I Sbjct: 573 VCNLASLVLSNIDLSDDK-----ELREVVRVAVRALDNVIDLTYYPVPYAQVTNAYYRAI 627 Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 G+GV G + +ES E + ++ + A+EAS +A Sbjct: 628 GLGVSGYHHVLAQQGIDWESDEHLAFADRIFERINRAAIEASMTIA 673 Score = 55.2 bits (127), Expect = 1e-06 Identities = 28/80 (35%), Positives = 46/80 (57%), Gaps = 1/80 (1%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQ 183 L D + +E+E Y K+ R + + + L + ++++ VETGTP+ ++D NR + Sbjct: 465 LEDFYAEEWEKRYWDCVKDARISKRTIPIKELVRLVLKSVVETGTPFAFYRDHANRANPN 524 Query: 184 KNLGTIKCSNLCTEIVEYTS 243 + G I CSNLCTEI + S Sbjct: 525 GHRGIIYCSNLCTEIAQNMS 544 >UniRef50_O66503 Cluster: Ribonucleoside-diphosphate reductase subunit alpha; n=1; Aquifex aeolicus|Rep: Ribonucleoside-diphosphate reductase subunit alpha - Aquifex aeolicus Length = 801 Score = 65.3 bits (152), Expect = 1e-09 Identities = 33/82 (40%), Positives = 47/82 (57%), Gaps = 2/82 (2%) Frame = +1 Query: 4 GLADCWGKEFESLYETYEKE--NRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKS 177 GL D +G+EFE Y E+ + +V + LWK ++ ETG PY+ F+D NRK+ Sbjct: 412 GLEDFYGEEFEKWYLELEENLPSYAKKKVNSFELWKRLLTVAFETGEPYIFFRDEANRKN 471 Query: 178 NQKNLGTIKCSNLCTEIVEYTS 243 K+ G + SNLC EIV+ S Sbjct: 472 PNKHTGMVYSSNLCHEIVQTMS 493 Score = 65.3 bits (152), Expect = 1e-09 Identities = 36/105 (34%), Positives = 58/105 (55%) Frame = +3 Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437 VCNL S+ L K + +++KEV + L+ +I++N+Y +PEA+ +N R+R IG Sbjct: 520 VCNLGSVNLG------KVHTEEEIKEVLPLLVRMLDNVIEMNFYAIPEAEYTNKRYRAIG 573 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IGV + + +ES E + +K +L AL+ S ELA Sbjct: 574 IGVSNYHYCLVKNGIKWESEEHLKFADKLFELIAFYALKGSLELA 618 >UniRef50_Q2VSI0 Cluster: Ribonucleoside-diphosphate reductase; n=2; Ovine herpesvirus 2|Rep: Ribonucleoside-diphosphate reductase - Ovine herpesvirus 2 Length = 785 Score = 63.7 bits (148), Expect = 4e-09 Identities = 30/82 (36%), Positives = 50/82 (60%), Gaps = 1/82 (1%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186 L +G+EF+ YE +E R+V QV + L +II ++TG+PY+++KD+CN ++ Sbjct: 329 LPHLYGEEFKEEYERLVRERRYVGQVIIKSLLFSIINTIIKTGSPYIIYKDACNAHHWKE 388 Query: 187 NLG-TIKCSNLCTEIVEYTSDD 249 G I +NLC E+++Y D Sbjct: 389 MRGQAIASANLCAEVIQYPGRD 410 Score = 33.1 bits (72), Expect = 6.6 Identities = 17/37 (45%), Positives = 19/37 (51%) Frame = +3 Query: 393 VPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEA 503 V E + R R +GIGV GLAD F M Y P A Sbjct: 481 VTEGMQRGQRERSMGIGVHGLADVFAEMGYSYLDPAA 517 >UniRef50_Q5KX82 Cluster: Ribonucleoside-diphosphate reductase; n=8; Firmicutes|Rep: Ribonucleoside-diphosphate reductase - Geobacillus kaustophilus Length = 857 Score = 63.7 bits (148), Expect = 4e-09 Identities = 39/107 (36%), Positives = 54/107 (50%), Gaps = 1/107 (0%) Frame = +3 Query: 255 AVCNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 +VCNLA+I L VD + K +++KLK + + +ID Y + E KK L R Sbjct: 487 SVCNLAAINLANMVDKERKVIDYEKLKRTVEIGVRMQDNVIDATPYFLEENKKQALGERR 546 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+GV GLAD I Y S E +++ + A AS ELA Sbjct: 547 IGLGVMGLADLLIYCEKAYGSEEGNQLVDELFRTIATTAYRASIELA 593 >UniRef50_A0B8R8 Cluster: Ribonucleoside-diphosphate reductase; n=2; Methanomicrobia|Rep: Ribonucleoside-diphosphate reductase - Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrixthermophila (strain DSM 6194 / PT)) Length = 688 Score = 63.3 bits (147), Expect = 5e-09 Identities = 32/103 (31%), Positives = 56/103 (54%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL S+ L+ V+ + ++ +L+E + L+ +ID N +P+ + + + LR R IG+ Sbjct: 394 CNLGSVNLSRMVERGEI-SWDRLEETVRLAVRFLDDVIDANRFPLKQIEDATLRTRKIGL 452 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCEL 569 GV G A+ I + + Y S +A+ + + T A E SC L Sbjct: 453 GVMGFAEMLIQLGVSYASQDALRIAEELMAFITKTAREESCAL 495 >UniRef50_P74240 Cluster: Ribonucleoside-diphosphate reductase subunit alpha; n=2; Chroococcales|Rep: Ribonucleoside-diphosphate reductase subunit alpha - Synechocystis sp. (strain PCC 6803) Length = 767 Score = 62.9 bits (146), Expect = 7e-09 Identities = 31/77 (40%), Positives = 45/77 (58%), Gaps = 4/77 (5%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKEN----RFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRK 174 LA+ WG++FE Y E ++ A+ L+K I+ QVETG PY+ FKD+ N+ Sbjct: 388 LAELWGEQFEGAYREIESNLDTTITLYKRINARELFKQIMRTQVETGMPYLSFKDTINKA 447 Query: 175 SNQKNLGTIKCSNLCTE 225 + K+LG I +NLC E Sbjct: 448 NPNKHLGYIPGTNLCCE 464 Score = 39.5 bits (88), Expect = 0.076 Identities = 25/83 (30%), Positives = 39/83 (46%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL S+ L + + + V++ L+ I++ P +AK N ++R IG+ Sbjct: 478 CNLVSLNL-------ANLDLQDIAGVSQIAVRMLDNTIELTAPPFADAKSHNNKYRTIGV 530 Query: 441 GVQGLADAFILMRLPYESPEAIN 509 G GLAD RL Y+ IN Sbjct: 531 GAMGLADWLAKRRLNYDELADIN 553 >UniRef50_Q18UV0 Cluster: Ribonucleoside-diphosphate reductase; n=4; Bacteria|Rep: Ribonucleoside-diphosphate reductase - Desulfitobacterium hafniense (strain DCB-2) Length = 1153 Score = 62.5 bits (145), Expect = 9e-09 Identities = 34/107 (31%), Positives = 56/107 (52%), Gaps = 3/107 (2%) Frame = +3 Query: 261 CNLASIALNMFVDDNK---TYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 CNL SI L + V + ++++L ++T+ T L+ +I+ N YP+P ++ +R Sbjct: 661 CNLGSINLKLMVTEKNGKVVVDWERLGQITRLATRFLDNVIEANTYPLPSIEEMVKGNRK 720 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+GV G AD IL++ Y S +A+ K + A S LA Sbjct: 721 IGLGVMGFADMLILLQTSYASEDAVEYAEKVMNFIQTEARLESQRLA 767 >UniRef50_Q4C9K9 Cluster: Ribonucleoside-diphosphate reductase; n=4; Cyanobacteria|Rep: Ribonucleoside-diphosphate reductase - Crocosphaera watsonii Length = 1116 Score = 62.1 bits (144), Expect = 1e-08 Identities = 31/75 (41%), Positives = 46/75 (61%), Gaps = 4/75 (5%) Frame = +1 Query: 7 LADCWGKEFESLYETYE----KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRK 174 LA+ WG++FE Y E +E +V A+ L+K I+ +QVETG PY+ FKD+ N+ Sbjct: 390 LAELWGEKFEEAYGLIEAELDREITLYKRVNARELFKTIMRSQVETGMPYLAFKDTINKA 449 Query: 175 SNQKNLGTIKCSNLC 219 + K++G I NLC Sbjct: 450 NPNKHVGYIPGVNLC 464 Score = 39.1 bits (87), Expect = 0.10 Identities = 26/78 (33%), Positives = 38/78 (48%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL S+ L ++ Y L ++ I +N ID+ P +AK N R+R +G+ Sbjct: 827 CNLVSLNLANIEEEELDY----LCNISVRILDNT---IDITNPPFNDAKAHNDRYRTVGV 879 Query: 441 GVQGLADAFILMRLPYES 494 G GLAD L YE+ Sbjct: 880 GCMGLADWLAKKGLTYEN 897 >UniRef50_Q97ZH9 Cluster: Ribonucleoside-diphosphate reductase; n=4; Sulfolobaceae|Rep: Ribonucleoside-diphosphate reductase - Sulfolobus solfataricus Length = 841 Score = 62.1 bits (144), Expect = 1e-08 Identities = 37/107 (34%), Positives = 56/107 (52%), Gaps = 3/107 (2%) Frame = +3 Query: 261 CNLASIALNMFV---DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 CNL SI L FV D ++ L E+ + L+ +ID N YP+ + + + R R Sbjct: 464 CNLGSINLEKFVIERDGKAAIDWDGLAEIIRYGVRFLDNVIDANRYPLKQIEDATKRTRK 523 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 +G+GV GLA FI + + Y+S +AI + K A +AS E+A Sbjct: 524 VGLGVMGLARMFIKLGIAYDSVDAIYLSYQLAKFIFYHAYKASIEIA 570 Score = 37.5 bits (83), Expect = 0.31 Identities = 20/56 (35%), Positives = 30/56 (53%) Frame = +1 Query: 58 KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 KE V V A+ L+ I++ ++G P +LF D+ NR+ LG I +N C E Sbjct: 400 KEGAVVKYVNAKSLFDEIVKGAWDSGDPGLLFIDTINRRHPVWYLGKINATNPCGE 455 >UniRef50_UPI00015BC77F Cluster: UPI00015BC77F related cluster; n=1; unknown|Rep: UPI00015BC77F UniRef100 entry - unknown Length = 1005 Score = 61.7 bits (143), Expect = 2e-08 Identities = 30/90 (33%), Positives = 50/90 (55%) Frame = +3 Query: 303 NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRL 482 N T++++K K V + L+ +ID NYY + +K + R IG+G G D ++L Sbjct: 513 NNTFDWEKFKAVIRKAIRFLDNVIDANYYALEAVEKGTKQSRKIGLGFMGYQDMIEKLKL 572 Query: 483 PYESPEAIN*INKYLKLFTMGALEASCELA 572 P +S EA+ ++K + + A+E S ELA Sbjct: 573 PVDSKEALKLLDKIGETMSYVAIETSVELA 602 Score = 48.8 bits (111), Expect = 1e-04 Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 4/90 (4%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVX----QVRAQVLWKAIIEAQVETGTPYMLFKDSCN 168 P L +GK+F Y ++ +++A L+K IE ++TG P+ FKD N Sbjct: 383 PKLVSTYGKKFSREYSKCIRKALSGKIRHKKIKAVELFKEAIENTIQTGEPWYTFKDPIN 442 Query: 169 RKSNQKNLGTIKCSNLCTEIVEYTSDDEVQ 258 + K+ GTI +NLCTE + ++ D ++ Sbjct: 443 IRHPNKHTGTILTTNLCTEQLLVSTYDSIE 472 >UniRef50_Q5SM68 Cluster: Ribonucleoside-diphosphate reductase; n=5; Thermus thermophilus|Rep: Ribonucleoside-diphosphate reductase - Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) Length = 2202 Score = 60.5 bits (140), Expect = 4e-08 Identities = 32/104 (30%), Positives = 59/104 (56%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 C+L ++ L +V D + + ++ + +T L+ ++DVN + +P+ + + + R +G+ Sbjct: 1306 CDLGAMNLAAYVKDGE-FQMEEFRRDVRTAIRFLDNVLDVNKFALPDNEMAAKKLRRLGL 1364 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 G+ GLADA I M LPY+S EA + + + A+ AS LA Sbjct: 1365 GLMGLADALIKMGLPYDSEEARRKVYEIVSAMREEAIRASEALA 1408 >UniRef50_A5TVY2 Cluster: Ribonucleoside-diphosphate reductase; n=3; Fusobacterium nucleatum|Rep: Ribonucleoside-diphosphate reductase - Fusobacterium nucleatum subsp. polymorphum ATCC 10953 Length = 755 Score = 60.5 bits (140), Expect = 4e-08 Identities = 29/75 (38%), Positives = 46/75 (61%), Gaps = 2/75 (2%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQ--VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 L + +G EFE+LYE E + + + A+ L+K+I++ Q+ETG PY+ FKD N ++ Sbjct: 369 LCELYGYEFENLYEKIENDPNIKLKKVLSAKELFKSIMKTQLETGMPYIFFKDRANEVNH 428 Query: 181 QKNLGTIKCSNLCTE 225 ++G I NLC E Sbjct: 429 NSHMGMIGNGNLCME 443 Score = 48.4 bits (110), Expect = 2e-04 Identities = 34/104 (32%), Positives = 52/104 (50%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL SI L + +L++ L+ ID+ P+ E+ K NL +R IG+ Sbjct: 475 CNLISINLAELTSE-------ELEKHVALAVRALDNTIDLTVTPLKESNKHNLLYRTIGV 527 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 G GLAD + YE E+IN IN+ + + +++AS LA Sbjct: 528 GAMGLADYLAREYMIYE--ESINEINELFERIALYSIKASALLA 569 >UniRef50_Q9IBT4 Cluster: Ribonucleoside-diphosphate reductase; n=6; Mardivirus|Rep: Ribonucleoside-diphosphate reductase - Meleagrid herpesvirus 1 (MeHV-1) (Turkey herpesvirus) Length = 822 Score = 59.3 bits (137), Expect = 9e-08 Identities = 31/73 (42%), Positives = 43/73 (58%), Gaps = 1/73 (1%) Frame = +1 Query: 25 KEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLG-TI 201 +EFE YE E E V + + + AII++ TG+P++LFKD+CNR G I Sbjct: 407 EEFEKEYERLESEGLGVASIPIRDMMFAIIKSAASTGSPFILFKDACNRHYITNTQGDAI 466 Query: 202 KCSNLCTEIVEYT 240 SNLCTEI++ T Sbjct: 467 AGSNLCTEIIQKT 479 Score = 52.0 bits (119), Expect = 1e-05 Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 4/113 (3%) Frame = +3 Query: 252 SAVCNLASIALNMFV---DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422 + VC+LASI L V D N+ ++F L+ + T +N I++ + P ++ R Sbjct: 484 NGVCSLASINLARCVRNIDGNRQFDFDALRYAVRLATVFVNAIMEGSDVPTEKSHSGRER 543 Query: 423 HRPIGIGVQGLADAFILMRLPYESPEAIN*INKYL-KLFTMGALEASCELAAK 578 +R +GIGVQG AF+ M L E +NK + + + A+ SCE + Sbjct: 544 NRSMGIGVQGFHTAFLSMGLDL-CDERARSLNKLIFEFMLLEAMTVSCEFCER 595 >UniRef50_Q5LNK9 Cluster: Ribonucleoside-diphosphate reductase, putative; n=22; Alphaproteobacteria|Rep: Ribonucleoside-diphosphate reductase, putative - Silicibacter pomeroyi Length = 760 Score = 58.8 bits (136), Expect = 1e-07 Identities = 34/103 (33%), Positives = 53/103 (51%) Frame = +3 Query: 264 NLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIG 443 NLA + N F +D + + L+++ T ++ ++D + +P+PE R IG+G Sbjct: 285 NLARLVSNPF-EDAAELDPEALQKLVATAVRMMDNVVDASRFPLPEQAAEAQNKRRIGLG 343 Query: 444 VQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 V GLADA +++ L Y S EA +L A AS ELA Sbjct: 344 VTGLADALLMLGLRYGSDEAAKQTEDWLHAIARAAYLASVELA 386 Score = 34.3 bits (75), Expect = 2.9 Identities = 16/48 (33%), Positives = 25/48 (52%) Frame = +1 Query: 82 VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 V A+ LW I++A + P ++F D N +N + TI +N C E Sbjct: 223 VEARTLWNKIMQATYDYAEPGVIFIDRINAANNLNYVETIAATNPCGE 270 >UniRef50_A3H704 Cluster: Ribonucleoside-diphosphate reductase; n=1; Caldivirga maquilingensis IC-167|Rep: Ribonucleoside-diphosphate reductase - Caldivirga maquilingensis IC-167 Length = 877 Score = 58.8 bits (136), Expect = 1e-07 Identities = 33/104 (31%), Positives = 54/104 (51%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL SI L +++ N + ++ L L+ +ID N +P ++N R IG+ Sbjct: 486 CNLGSINLTKYINGN-SIDWVSLANDIMLAVRFLDDVIDSNQHPHEYLDRANKASRRIGL 544 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 G+ G AD + + +PY+SP+AI + + A+ AS ELA Sbjct: 545 GINGWADVLVSLDIPYDSPKAIALADVVMGFVARVAVRASVELA 588 >UniRef50_A3JKM6 Cluster: Ribonucleoside reductase; n=1; Marinobacter sp. ELB17|Rep: Ribonucleoside reductase - Marinobacter sp. ELB17 Length = 1087 Score = 58.0 bits (134), Expect = 2e-07 Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 4/86 (4%) Frame = +3 Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 C L S+ L MFVDD T +N++K K+V T L+ ++++N P+ + + R Sbjct: 706 CLLGSVNLTMFVDDPFTDKASFNYEKYKKVVGIFTRMLDNVVEINGLPLAQQRHEITYKR 765 Query: 429 PIGIGVQGLADAFILMRLPYESPEAI 506 G+G+ GL ++R+PY S E++ Sbjct: 766 RHGMGILGLGSTLAMLRMPYGSEESV 791 >UniRef50_Q9PE32 Cluster: Ribonucleoside-diphosphate reductase; n=34; root|Rep: Ribonucleoside-diphosphate reductase - Xylella fastidiosa Length = 830 Score = 57.6 bits (133), Expect = 3e-07 Identities = 27/69 (39%), Positives = 44/69 (63%), Gaps = 1/69 (1%) Frame = +1 Query: 31 FESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKC 207 F YE + R + V+A ++K I+ +Q+ETG P+M ++D NRK+ K++G + Sbjct: 456 FRRKYEDVVADERISRKTVKAIDIFKRIMVSQLETGNPFMFYRDEVNRKNPNKHVGMVYS 515 Query: 208 SNLCTEIVE 234 SNLCTEI++ Sbjct: 516 SNLCTEILQ 524 Score = 45.6 bits (103), Expect = 0.001 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 1/106 (0%) Frame = +3 Query: 258 VCNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 VCNL+SI L + L+ + L+ +ID+N PVP+A +N ++R I Sbjct: 552 VCNLSSINLGRAITVQADLLGADVLERLIPIQVRMLDNVIDLNLLPVPQATITNQKYRAI 611 Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 G+G G + + SPEA + + + AS ELA Sbjct: 612 GLGTFGWHHLLAQKAIHWNSPEAEQYSDALYERINYLTIRASMELA 657 >UniRef50_A1YJD3 Cluster: Ribonucleoside-diphosphate reductase; n=1; Spodoptera frugiperda MNPV|Rep: Ribonucleoside-diphosphate reductase - Spodoptera frugiperda nuclear polyhedrosis virus (SfNPV) Length = 839 Score = 57.2 bits (132), Expect = 4e-07 Identities = 34/103 (33%), Positives = 63/103 (61%), Gaps = 2/103 (1%) Frame = +3 Query: 270 ASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGV 446 AS+A++ V+ + K +++ L+ +TK + +L+ +I++N YP+ K N +H I +G+ Sbjct: 519 ASVAVDKCVNLETKQFDYNLLRRITKNVVRDLDAMININMYPLD--KFENKKHN-IAVGM 575 Query: 447 QGLADAFILMRLPYESPEAIN*INKYL-KLFTMGALEASCELA 572 QG A+ +L+ ++ EA +NK + + GA+EAS ELA Sbjct: 576 QGFAETLLLLGYTFDMVEA-KALNKLIAETIYYGAIEASNELA 617 Score = 35.1 bits (77), Expect = 1.6 Identities = 19/54 (35%), Positives = 30/54 (55%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCN 168 L+ +G +FE Y +EKE+ V+A+ L K II+ G ++FKD+ N Sbjct: 448 LSSKYGDKFEQAYVKFEKEHINAKIVKAKDLLKLIIDTMRINGNLSVMFKDTFN 501 >UniRef50_O33839 Cluster: Ribonucleoside-diphosphate reductase; n=4; Thermotogaceae|Rep: Ribonucleoside-diphosphate reductase - Thermotoga maritima Length = 827 Score = 57.2 bits (132), Expect = 4e-07 Identities = 31/103 (30%), Positives = 52/103 (50%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL SI + F + N + + L+E+ + L+ +IDVN +P+ + K+ R +G+ Sbjct: 333 CNLGSIDVAKFYN-NGFVDLEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGL 391 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCEL 569 G+ G AD + +PY S EA + + + A S EL Sbjct: 392 GIMGFADLLYKLEIPYNSQEARDFAANLMAFIALHAHRTSYEL 434 >UniRef50_A7I485 Cluster: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; n=1; Candidatus Methanoregula boonei 6A8|Rep: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent - Methanoregula boonei (strain 6A8) Length = 741 Score = 57.2 bits (132), Expect = 4e-07 Identities = 32/107 (29%), Positives = 59/107 (55%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 C L SI L V + ++ L++ ++ T L+ +I+ N +P+P+ ++ + R IG+ Sbjct: 266 CVLGSINLAACVREG-AFDEDLLRDTSRMATRFLDLVIEKNVFPIPQIAEATRKTRKIGL 324 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKV 581 GV G+ DA +++ L Y+S + +K+ T A+E S LA K+ Sbjct: 325 GVMGVHDAMLMLGLSYDSEKGRAWCEWVMKVITETAIEESHRLAEKL 371 Score = 35.1 bits (77), Expect = 1.6 Identities = 16/43 (37%), Positives = 22/43 (51%) Frame = +1 Query: 97 LWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 +W I+E + G P +LF D NR + LG I +N C E Sbjct: 215 IWNGIVEGIWKNGEPGILFYDEINRHNPTPQLGEIDTTNPCGE 257 >UniRef50_Q5P1D5 Cluster: Ribonucleotide reductase, Coenzyme B12-dependent; n=6; Betaproteobacteria|Rep: Ribonucleotide reductase, Coenzyme B12-dependent - Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum (strain EbN1)) Length = 963 Score = 56.4 bits (130), Expect = 6e-07 Identities = 36/131 (27%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +3 Query: 261 CNLASIALNMFVD----DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 C+L SI L F+ D +++ +V L+ ++DV ++P+P+ + R Sbjct: 312 CDLGSINLTPFIKHPFTDKAEFDYPAFGKVVDVAIRMLDNVLDVTHWPLPQQENEAQSKR 371 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTD 608 +G+G GL DA I++ Y+SP+A K + A AS ELA + + D Sbjct: 372 RVGLGFTGLGDALIMLCKRYDSPDARAVATKISEYMRDRAYLASVELAKERGAFPLFNAD 431 Query: 609 APASRGHITVR 641 S G+ R Sbjct: 432 LYLSGGNFASR 442 >UniRef50_Q2RP92 Cluster: Ribonucleotide reductase large subunit; n=1; Rhodospirillum rubrum ATCC 11170|Rep: Ribonucleotide reductase large subunit - Rhodospirillum rubrum (strain ATCC 11170 / NCIB 8255) Length = 786 Score = 56.4 bits (130), Expect = 6e-07 Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 4/110 (3%) Frame = +3 Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 CNL + L + V D T ++ +L EV L+ ++DV+ +PV + K R Sbjct: 296 CNLGCVNLAVLVRDPFTPQARFDDARLAEVAAIGVRFLDNVLDVSNFPVEDQAKEAQAKR 355 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 +G+G+ GL +A ++ L Y SP AI + + L A AS ELA + Sbjct: 356 RLGLGIMGLGNALQMLGLRYGSPAAIAETRRIMALLRDAAYRASAELAGE 405 Score = 36.7 bits (81), Expect = 0.54 Identities = 16/49 (32%), Positives = 26/49 (53%) Frame = +1 Query: 79 QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 ++ A+ LW+ II + P ++F D N ++N TI C+N C E Sbjct: 239 RLSARALWEKIIRTTYDHAEPGVIFIDRVNERNNLAYCETISCTNPCGE 287 >UniRef50_A6NX38 Cluster: Ribonucleoside-diphosphate reductase; n=1; Bacteroides capillosus ATCC 29799|Rep: Ribonucleoside-diphosphate reductase - Bacteroides capillosus ATCC 29799 Length = 784 Score = 56.4 bits (130), Expect = 6e-07 Identities = 36/107 (33%), Positives = 53/107 (49%), Gaps = 3/107 (2%) Frame = +3 Query: 261 CNLASIAL--NMFVDDNKTYNFK-KLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 CNL SI L ++ +D + K KL +T L+ +I+VN YP+PE R Sbjct: 282 CNLGSINLVTHLKEEDGRWVLDKDKLTATIRTAVHFLDNVIEVNKYPLPEIDAMTRSTRK 341 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+GV G AD + M +PY S + + + ++L E S LA Sbjct: 342 IGLGVMGFADMLLYMGIPYNSDQGVAMAREVMELVNTIGHEESQALA 388 >UniRef50_Q9YA77 Cluster: Ribonucleoside-diphosphate reductase; n=2; Desulfurococcales|Rep: Ribonucleoside-diphosphate reductase - Aeropyrum pernix Length = 979 Score = 56.4 bits (130), Expect = 6e-07 Identities = 26/82 (31%), Positives = 49/82 (59%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL S++++ +V + ++ ++ + +TE ++ +ID+N +P +N R IG+ Sbjct: 478 CNLGSLSVDKYVAGGR-FDLERFANDVEFLTEAMDAVIDLNRHPDERQDTANKFTRKIGL 536 Query: 441 GVQGLADAFILMRLPYESPEAI 506 G+ GLADA + PY+S EA+ Sbjct: 537 GIMGLADALAGLGYPYDSEEAV 558 Score = 34.3 bits (75), Expect = 2.9 Identities = 16/50 (32%), Positives = 28/50 (56%) Frame = +1 Query: 88 AQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVEY 237 A+ +W+ I+EA G P +++ D+ N+ S LG + +N C+E Y Sbjct: 424 AREIWREIVEAAWGGGDPGLVYFDNHNKWSPTPWLGAVNATNPCSEQTLY 473 >UniRef50_P09853 Cluster: Ribonucleoside-diphosphate reductase large chain; n=9; Simplexvirus|Rep: Ribonucleoside-diphosphate reductase large chain - Human herpesvirus 2 (strain 333) (HHV-2) (Human herpes simplex virus2) Length = 1144 Score = 56.4 bits (130), Expect = 6e-07 Identities = 35/80 (43%), Positives = 45/80 (56%), Gaps = 1/80 (1%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186 LAD G+EFE LYE E F + Q L AI+ + TG+P+++FKD+ NR Sbjct: 730 LADFHGEEFEKLYEHLEAMG-FGETIPIQDLAYAIVRSAATTGSPFIMFKDAVNRHYIYD 788 Query: 187 NLG-TIKCSNLCTEIVEYTS 243 G I SNLCTEIV +S Sbjct: 789 TQGAAIAGSNLCTEIVHPSS 808 Score = 52.0 bits (119), Expect = 1e-05 Identities = 32/109 (29%), Positives = 54/109 (49%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 S VCNL S+ L V +T++F L++ + +N +ID P P+ + + R Sbjct: 812 SGVCNLGSVNLARCVS-RRTFDFGMLRDAVQACVLMVNIMIDSTLQPTPQCARGHDNLRS 870 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 +GIG+QGL A + M L ES E + ++ + A++ S L + Sbjct: 871 MGIGMQGLHTACLKMGLDLESAEFRDLNTHIAEVMLLAAMKTSNALCVR 919 >UniRef50_A7KUZ9 Cluster: Nrd alpha subunit; n=1; Bacillus phage 0305phi8-36|Rep: Nrd alpha subunit - Bacillus phage 0305phi8-36 Length = 767 Score = 56.0 bits (129), Expect = 8e-07 Identities = 36/105 (34%), Positives = 54/105 (51%) Frame = +3 Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437 VCNLAS+ L V L V + +T L+ IID+N V +A +N R+RPIG Sbjct: 495 VCNLASVNLAKAVPAGV------LARVIRIVTRMLDNIIDINTISVLQAGITNKRYRPIG 548 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 +G G ++ L +ES A+N + + F +++S ELA Sbjct: 549 MGAYGWHHLLAILGLDWESEAAVNYADTLYEEFAYHVIDSSVELA 593 Score = 47.6 bits (108), Expect = 3e-04 Identities = 24/55 (43%), Positives = 33/55 (60%), Gaps = 5/55 (9%) Frame = +1 Query: 85 RAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNL-----GTIKCSNLCTEIVE 234 RA + I+E Q+ETG PYM ++D NR + K++ I CSNLCTEI + Sbjct: 412 RAMDIMVRIMEIQLETGMPYMFYRDQVNRMNPNKHVHGIGRTAIYCSNLCTEIAQ 466 >UniRef50_A7HK53 Cluster: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; n=1; Fervidobacterium nodosum Rt17-B1|Rep: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent - Fervidobacterium nodosum Rt17-B1 Length = 841 Score = 55.6 bits (128), Expect = 1e-06 Identities = 27/80 (33%), Positives = 45/80 (56%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL SI + F + + Y ++ + T+ L+ +IDVN +P+ + +K+ R IG+ Sbjct: 339 CNLGSIDVAKFYMNGEFY-WEAFAQATRLAVRFLDDVIDVNVFPLEKIRKAVTDSRRIGL 397 Query: 441 GVQGLADAFILMRLPYESPE 500 G+ G AD +M +PY S E Sbjct: 398 GIMGFADLLYMMDIPYNSHE 417 >UniRef50_Q9RZL7 Cluster: Ribonucleoside-diphosphate reductase; n=2; Deinococcus|Rep: Ribonucleoside-diphosphate reductase - Deinococcus radiodurans Length = 702 Score = 55.2 bits (127), Expect = 1e-06 Identities = 29/75 (38%), Positives = 47/75 (62%) Frame = +1 Query: 19 WGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGT 198 W KE+++L + + +V A+ L + I Q E+G PY+LF+ + NR + N+GT Sbjct: 319 WTKEYQALADNPNIRKK---RVSARRLLEDIAVTQGESGYPYLLFEGNANRANPIPNVGT 375 Query: 199 IKCSNLCTEIVEYTS 243 IK SNLC+EI++ T+ Sbjct: 376 IKMSNLCSEILQPTT 390 Score = 39.9 bits (89), Expect = 0.058 Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 1/105 (0%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKII-DVNYYPVPEAKKSNLRHRPIG 437 CNLAS+ + +T + L V L+ + + + VP K++N R IG Sbjct: 411 CNLASLVIE------QTMHGGDLGRVVGAAIRMLDNVARSTSVHEVPAVKRANDEMRSIG 464 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 +G GL L Y SPEA+ ++ + A +AS E+A Sbjct: 465 LGAMGLHSFLAGKELIYGSPEALEFVDVFFAAVHYHARKASMEIA 509 >UniRef50_Q21U31 Cluster: Ribonucleoside-diphosphate reductase; n=1; Rhodoferax ferrireducens T118|Rep: Ribonucleoside-diphosphate reductase - Rhodoferax ferrireducens (strain DSM 15236 / ATCC BAA-621 / T118) Length = 589 Score = 55.2 bits (127), Expect = 1e-06 Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 4/108 (3%) Frame = +3 Query: 261 CNLASIALNMFVDD----NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 CNL SI L+ FV + + + L+ V T L+ + D++ +P+ +KS L R Sbjct: 306 CNLGSINLSRFVQQPFAAHPSVDLGGLRAVAAVATRFLDDVYDISLFPLKAQQKSALASR 365 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+GV GLAD ++ L Y S +I+ + + A S ELA Sbjct: 366 RIGLGVTGLADMLAMLGLRYGSAASIDLTREIMGAIRDTAYRTSVELA 413 Score = 33.5 bits (73), Expect = 5.0 Identities = 14/34 (41%), Positives = 23/34 (67%) Frame = +1 Query: 79 QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 +V A+ LW+ +++AQ +G P +LF D NR +N Sbjct: 249 RVPARALWEKLLQAQHASGEPGVLFIDRINRANN 282 >UniRef50_A7IYE5 Cluster: Putivate ribonucleotide reductase; n=1; Corynebacterium phage P1201|Rep: Putivate ribonucleotide reductase - Corynebacterium phage P1201 Length = 865 Score = 55.2 bits (127), Expect = 1e-06 Identities = 25/61 (40%), Positives = 40/61 (65%), Gaps = 1/61 (1%) Frame = +1 Query: 40 LYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNL 216 +Y+T+ K++R + A+ L++ I E Q E+G PY++F D+ NR + N+G IK SNL Sbjct: 320 MYDTWLKDDRIAKTFIDARKLFQTIAEVQFESGYPYLMFDDAANRGNPAPNIGRIKSSNL 379 Query: 217 C 219 C Sbjct: 380 C 380 >UniRef50_Q89YE5 Cluster: Ribonucleoside-diphosphate reductase; n=49; root|Rep: Ribonucleoside-diphosphate reductase - Bradyrhizobium japonicum Length = 723 Score = 54.8 bits (126), Expect = 2e-06 Identities = 28/67 (41%), Positives = 42/67 (62%), Gaps = 3/67 (4%) Frame = +1 Query: 58 KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNR--KSNQKNLG-TIKCSNLCTEI 228 K N V ++ A+ LW+ I+E +++TG PY+LF D+ NR +Q+ LG + SNLC+EI Sbjct: 345 KTNEVVREIDARQLWQRILENRLQTGEPYLLFIDTVNRALPKHQRELGLEVSTSNLCSEI 404 Query: 229 VEYTSDD 249 T D Sbjct: 405 TLSTGID 411 >UniRef50_Q2LW62 Cluster: Ribonucleoside-diphosphate reductase alpha chain; n=1; Syntrophus aciditrophicus SB|Rep: Ribonucleoside-diphosphate reductase alpha chain - Syntrophus aciditrophicus (strain SB) Length = 551 Score = 54.0 bits (124), Expect = 3e-06 Identities = 33/106 (31%), Positives = 57/106 (53%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 C L SI L+ V N ++++L+++T L+ +++V+ YP E + +R IG+ Sbjct: 285 CCLGSINLSRIVR-NGGIDWQRLQKLTHLGVRFLDDVVEVSTYPSEEIRAMTSGNRKIGL 343 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 GV G A I + +PY+SP+A + ++L + AS LA K Sbjct: 344 GVMGFAHLLIRLGIPYDSPDAERTGGEIIRLIERESKIASNRLAEK 389 Score = 34.3 bits (75), Expect = 2.9 Identities = 17/49 (34%), Positives = 29/49 (59%) Frame = +1 Query: 79 QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 +V A+ L + I EA +G P ++F D+ NR + ++G I+ +N C E Sbjct: 228 KVNARELLRFIAEAAWASGEPGVIFLDAINRANPTPHVGEIEATNPCGE 276 >UniRef50_Q18BC3 Cluster: Putative ribonucleotide-diphosphate reductase; n=2; Clostridium difficile|Rep: Putative ribonucleotide-diphosphate reductase - Clostridium difficile (strain 630) Length = 729 Score = 53.6 bits (123), Expect = 4e-06 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 6/88 (6%) Frame = +3 Query: 261 CNLASIALNMFV----DDNKTYNFKKLKEVTKTITENLNKIID--VNYYPVPEAKKSNLR 422 C L SI L+ F+ ++ T++ KLK + LN ++D +N +P+ E + S + Sbjct: 364 CLLGSINLSEFIIQPFGEHATFDINKLKSCVREAVVALNDVLDEGLNLHPLQEQRDSVHK 423 Query: 423 HRPIGIGVQGLADAFILMRLPYESPEAI 506 +R IG+GV G+AD I M + Y S E++ Sbjct: 424 YRQIGLGVMGIADMLIKMGIRYGSDESL 451 >UniRef50_Q01037 Cluster: Ribonucleoside-diphosphate reductase large chain; n=12; Herpesviridae|Rep: Ribonucleoside-diphosphate reductase large chain - Saimiriine herpesvirus 2 (strain 11) (SaHV-2) (Herpesvirus saimiri) Length = 767 Score = 53.6 bits (123), Expect = 4e-06 Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 1/79 (1%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSN 180 P L +G EFE Y E ++ V + L ++I ++TG+PY++ K++ N+ Sbjct: 321 PNLTRLYGLEFEEEYLRLVSEKKYKQSVTLKSLMFSLINTIIKTGSPYVISKEAMNKHHW 380 Query: 181 QKNLG-TIKCSNLCTEIVE 234 + G I CSNLC EIV+ Sbjct: 381 YETQGEAINCSNLCAEIVQ 399 >UniRef50_A3EPA5 Cluster: Ribonucleoside-diphosphate reductase; n=1; Leptospirillum sp. Group II UBA|Rep: Ribonucleoside-diphosphate reductase - Leptospirillum sp. Group II UBA Length = 732 Score = 53.2 bits (122), Expect = 6e-06 Identities = 31/108 (28%), Positives = 50/108 (46%), Gaps = 4/108 (3%) Frame = +3 Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 CNL SI L V + T ++++L L+ ++D N +P+PE N R Sbjct: 285 CNLGSINLERHVRSSATGKPEVDWERLGRSVYLAVRFLDNVVDANRFPIPELAAVNQGTR 344 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+G+ G A + + +PY+S E + K + A S +LA Sbjct: 345 RIGLGIMGFARLLMRLEIPYDSEEGLEMAEKVMSFIRDEAERTSQDLA 392 >UniRef50_A2PYM5 Cluster: Ribonucleoside-diphosphate reductase alpha subunit; n=4; Cyanophage Ma|Rep: Ribonucleoside-diphosphate reductase alpha subunit - Cyanophage Ma-LMM02 Length = 742 Score = 53.2 bits (122), Expect = 6e-06 Identities = 31/80 (38%), Positives = 43/80 (53%), Gaps = 7/80 (8%) Frame = +1 Query: 7 LADCWGKEFESLY---ETYEKENR----FVXQVRAQVLWKAIIEAQVETGTPYMLFKDSC 165 LAD +G EF + Y E Y + V +V A+ +WK ++ +ETGTPY+ FKD Sbjct: 365 LADMYGDEFTNAYHVIEAYINSSAPPLDVVKKVSAKAIWKKMLMLLLETGTPYVAFKDRI 424 Query: 166 NRKSNQKNLGTIKCSNLCTE 225 N + K+ G I NLC E Sbjct: 425 NALNPNKHEGIIGGVNLCVE 444 Score = 50.0 bits (114), Expect = 5e-05 Identities = 35/107 (32%), Positives = 51/107 (47%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 S C L S+ L DD ++ +V++T L+ D+ P PEA+ R+R Sbjct: 454 SHCCMLLSLVLPRIADD-------EMADVSRTAVRLLDAACDLTTSPTPEARAHVNRYRT 506 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+GV GLAD + L Y+ +N I K + +AS ELA Sbjct: 507 IGVGVMGLADWLAIRHLRYQD---LNLIEKLFEDICFYTTQASVELA 550 >UniRef50_O36411 Cluster: Ribonucleoside-diphosphate reductase; n=1; Alcelaphine herpesvirus 1|Rep: Ribonucleoside-diphosphate reductase - Alcelaphine herpesvirus 1 (wildebeest herpesvirus) Length = 780 Score = 52.8 bits (121), Expect = 8e-06 Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 2/83 (2%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186 LA+ +G EF S YE + + + L II ++TG+PY+++K++CN + + K Sbjct: 324 LANLYGDEFRSEYERLVGIGCYADAIPIKSLMFLIINTIIKTGSPYIIYKEACN-EHHWK 382 Query: 187 NLG--TIKCSNLCTEIVEYTSDD 249 N+ I +NLC E+++Y D Sbjct: 383 NMEGCAIASANLCAEVIQYPGAD 405 >UniRef50_A3W1N9 Cluster: Ribonucleoside-diphosphate reductase; n=8; Bacteria|Rep: Ribonucleoside-diphosphate reductase - Roseovarius sp. 217 Length = 1131 Score = 52.8 bits (121), Expect = 8e-06 Identities = 33/121 (27%), Positives = 56/121 (46%) Frame = +3 Query: 264 NLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIG 443 NLA + F + + L ++ + ++ ++DV+ +P+P R IG+G Sbjct: 655 NLARLVTEPFATGARV-DAAALDDLVRVAVRMMDNVVDVSGFPLPAQAAEAQAKRRIGLG 713 Query: 444 VQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAPASR 623 V GLADA +++ L Y S EA+ +L A AS +LA + + DA + Sbjct: 714 VTGLADALLMVGLRYGSDEAVQQTEAWLHAIARAAYLASVDLAREKGAFPLFDRDAYLAS 773 Query: 624 G 626 G Sbjct: 774 G 774 Score = 34.3 bits (75), Expect = 2.9 Identities = 18/62 (29%), Positives = 28/62 (45%) Frame = +1 Query: 67 RFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVEYTSD 246 R V+A+ LW I++A + P ++F D N +N TI +N C + Sbjct: 216 RVYHTVQARDLWNRIMQATYDYAEPGVIFIDRINAANNLSYCETIAATNPCVTAETWVMT 275 Query: 247 DE 252 DE Sbjct: 276 DE 277 >UniRef50_A0MN59 Cluster: Ribonucleotide reductase alpha subunit; n=1; Thermus phage phiYS40|Rep: Ribonucleotide reductase alpha subunit - Thermus phage phiYS40 Length = 797 Score = 52.8 bits (121), Expect = 8e-06 Identities = 31/112 (27%), Positives = 57/112 (50%), Gaps = 8/112 (7%) Frame = +3 Query: 261 CNLASIALNMFVDD--------NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSN 416 CNL SI L+ FV + + ++F KL EV++ + L+ + D+ P+ + K++ Sbjct: 452 CNLGSIFLHRFVKEPFNYDLKPEENFDFDKLFEVSRLMNRFLDFVNDITNLPLVQLKEAA 511 Query: 417 LRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 R G+G+ G+AD I++ L Y S EA + K + + + + +A Sbjct: 512 FTKRRHGLGISGIADTLIMVGLRYGSEEAAKFLEKIMYTIQLASAVENVRMA 563 >UniRef50_P50643 Cluster: Ribonucleoside-diphosphate reductase large chain; n=18; Herpesviridae|Rep: Ribonucleoside-diphosphate reductase large chain - Pseudorabies virus (strain Kaplan) (PRV) Length = 835 Score = 52.8 bits (121), Expect = 8e-06 Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 1/83 (1%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQK 186 LA G +F YE E+ V + Q + I+ + V TG+P+++ KD+CNR + Sbjct: 420 LASLHGPDFAREYERLERLGLGVESLPIQDMAFLIVRSAVMTGSPFLMMKDACNRHFHTD 479 Query: 187 NLG-TIKCSNLCTEIVEYTSDDE 252 G + SNLCTEIV+ + E Sbjct: 480 TRGAALATSNLCTEIVQRATPGE 502 Score = 43.6 bits (98), Expect = 0.005 Identities = 27/109 (24%), Positives = 49/109 (44%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 + VCNLAS+ L + ++F L+ + +N ++ + YP + + R R Sbjct: 503 NGVCNLASVNLPACLAGG-AFDFAALRRAARVAAVFVNAMMRIGNYPTGASVEGVRRSRS 561 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 +GIG+QGL + + + P A + G ++AS EL + Sbjct: 562 LGIGLQGLHTTVLALDMDMADPAARRLNAAIAEELLYGVMDASVELCER 610 >UniRef50_Q7NEB4 Cluster: Gll3966 protein; n=1; Gloeobacter violaceus|Rep: Gll3966 protein - Gloeobacter violaceus Length = 1566 Score = 52.4 bits (120), Expect = 1e-05 Identities = 35/120 (29%), Positives = 61/120 (50%), Gaps = 5/120 (4%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKT---YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422 ++ CNL SI ++ F+ + +++ L + T L+ ++DV + P A+K N+R Sbjct: 1131 NSACNLGSIVISKFMHRTERGVELDWEDLARTVEISTRFLDNVLDVAEFATP-AQKHNVR 1189 Query: 423 H--RPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMI 596 + R +G+G+ G AD R+PY+S + I+K + A S LAA+ C I Sbjct: 1190 NVFRQLGLGIMGWADWLKARRIPYDSEAHLREIDKVGRFIAERAYRTSEALAAEKGACGI 1249 >UniRef50_A3I5A9 Cluster: Ribonucleoside-diphosphate reductase; n=1; Bacillus sp. B14905|Rep: Ribonucleoside-diphosphate reductase - Bacillus sp. B14905 Length = 697 Score = 52.0 bits (119), Expect = 1e-05 Identities = 25/68 (36%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Frame = +1 Query: 34 ESLYETYEKEN-RFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCS 210 E YE + R + ++ A+ L+ + +AQ E+G P+ +F D+ N KN+G +K S Sbjct: 317 EMYYELLDNPKIRKIKRLNARRLYTEVKKAQFESGYPFEIFDDNVNEVHPLKNIGRVKMS 376 Query: 211 NLCTEIVE 234 NLCTEI++ Sbjct: 377 NLCTEILQ 384 Score = 38.7 bits (86), Expect = 0.13 Identities = 26/122 (21%), Positives = 59/122 (48%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL SI ++ +K +F+ L + + N++++ + VP K+N +G+ Sbjct: 406 CNLGSIDIHAA---SKVNDFETLIDTAMHLLTNVSQMTYIKN--VPSVAKANRLMHSVGL 460 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAPAS 620 G L + + Y S ++I+ ++++++ +L++S E+A + E D+ + Sbjct: 461 GCMNLHGHLVTEGIMYGSKDSIDFMDRFMEAMNYYSLKSSMEMAKEKAETFYRFEDSDYA 520 Query: 621 RG 626 G Sbjct: 521 SG 522 >UniRef50_Q7UI46 Cluster: Vitamin B12-dependent ribonucleotide reductase; n=3; Bacteria|Rep: Vitamin B12-dependent ribonucleotide reductase - Rhodopirellula baltica Length = 1040 Score = 51.6 bits (118), Expect = 2e-05 Identities = 30/107 (28%), Positives = 49/107 (45%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNLASI L FV + +++ ++ + +T ++D YP +++ + RP+G+ Sbjct: 433 CNLASINLMKFVQQDGSFDHERFRAACRTFFIAQEILVDHASYPTEPIARNSHKFRPLGL 492 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKV 581 G L + LPY+S A L A S ELA+ V Sbjct: 493 GYSNLGSVIMTAGLPYDSDAARGMCGSLTALLHGEANRTSAELASVV 539 >UniRef50_A4IY36 Cluster: Ribonucleoside-diphosphate reductase, alpha chain; n=18; root|Rep: Ribonucleoside-diphosphate reductase, alpha chain - Francisella tularensis subsp. tularensis (strain WY96-3418) Length = 590 Score = 51.2 bits (117), Expect = 2e-05 Identities = 25/52 (48%), Positives = 36/52 (69%), Gaps = 3/52 (5%) Frame = +1 Query: 82 VRAQVLWKAIIEAQVETGTPYMLFKDSCNR--KSNQKNLG-TIKCSNLCTEI 228 ++A+ +W+ I+E + TG PY+ F D+ NR +QK+LG TIK SNLC EI Sbjct: 229 IKARKIWETILETRYRTGEPYLNFIDTANRALPKSQKDLGLTIKGSNLCNEI 280 Score = 39.5 bits (88), Expect = 0.076 Identities = 32/112 (28%), Positives = 53/112 (47%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 +AVC L+S+ L + D+ K + +K++ + + L ID + +A+ S R R Sbjct: 289 TAVCCLSSVNLERY-DEWKDTSL--IKDLIRFLDNVLQFFIDHAGDEISKARYSASRERS 345 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWE 587 +G+G G L R+P+ES A + K ALE + L A+ E Sbjct: 346 LGLGAMGFHSYLQLHRVPFESQRAKEINEEIFKRIKEQALEETLILGAEKGE 397 >UniRef50_Q1FPU1 Cluster: Ribonucleoside-diphosphate reductase; n=4; Clostridium|Rep: Ribonucleoside-diphosphate reductase - Clostridium phytofermentans ISDg Length = 764 Score = 50.8 bits (116), Expect = 3e-05 Identities = 23/59 (38%), Positives = 38/59 (64%) Frame = +1 Query: 82 VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVEYTSDDEVQ 258 V A + K I+++ VETG P++ F+D+ N+ + K+ G I SNLC EI + S+ E++ Sbjct: 413 VPALEVMKRIMKSAVETGAPFIFFRDTVNQANPNKHAGMIYSSNLCQEITQNMSESELR 471 >UniRef50_Q8Y2Y6 Cluster: Ribonucleoside-diphosphate reductase; n=12; Burkholderiaceae|Rep: Ribonucleoside-diphosphate reductase - Ralstonia solanacearum (Pseudomonas solanacearum) Length = 617 Score = 50.4 bits (115), Expect = 4e-05 Identities = 30/90 (33%), Positives = 45/90 (50%) Frame = +3 Query: 360 LNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFT 539 L+ ID+ +P+ E + R IG+GV GLADA +M LPY++PEA N + + Sbjct: 355 LDNAIDITRWPLIEHMREAHAKRRIGVGVTGLADALTMMGLPYQAPEARNLAVQIGRCLR 414 Query: 540 MGALEASCELAAKVWECMIHTTDAPASRGH 629 A AS LA + + + + GH Sbjct: 415 DNAYAASAALAQERSPYPLFRAERSLAPGH 444 Score = 34.7 bits (76), Expect = 2.2 Identities = 17/48 (35%), Positives = 26/48 (54%) Frame = +1 Query: 82 VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 V A+ LW ++EA + P +LF D+ N ++ L TI +N C E Sbjct: 260 VPARQLWDMLVEAAHHSAEPGLLFIDTINAANDLAELETIAATNPCGE 307 >UniRef50_A1HDY4 Cluster: Ribonucleoside-diphosphate reductase; n=1; Ralstonia pickettii 12J|Rep: Ribonucleoside-diphosphate reductase - Ralstonia pickettii 12J Length = 596 Score = 50.4 bits (115), Expect = 4e-05 Identities = 30/108 (27%), Positives = 50/108 (46%) Frame = +3 Query: 312 YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYE 491 ++F L + L+ I++ +P+PE R IG+GV GLADA +M LPY+ Sbjct: 327 FDFVGLSRAVRVQVRMLDNAIEITRWPLPEHMHEAQAKRRIGVGVTGLADALTMMCLPYD 386 Query: 492 SPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAPASRGHIT 635 +P A + + A AS LA + + + + + GH + Sbjct: 387 APAARCFAAQIGRCLRDSAYAASAALACERGPYPLFSPERSLAPGHFS 434 Score = 33.5 bits (73), Expect = 5.0 Identities = 17/48 (35%), Positives = 25/48 (52%) Frame = +1 Query: 82 VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 V A+ LW I EA + P +LF D+ N ++ + TI +N C E Sbjct: 248 VPARQLWNMIAEAAHHSAEPGLLFIDTINAANDLAEIETIAATNPCGE 295 >UniRef50_Q3B5C1 Cluster: Ribonucleotide reductase family protein; n=3; Chlorobium/Pelodictyon group|Rep: Ribonucleotide reductase family protein - Pelodictyon luteolum (strain DSM 273) (Chlorobium luteolum (strain DSM273)) Length = 1521 Score = 50.0 bits (114), Expect = 5e-05 Identities = 27/108 (25%), Positives = 53/108 (49%), Gaps = 1/108 (0%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTY-NFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 + CNLAS+ L FVD+ + +L+ T L + + ++P P+ + + +R Sbjct: 832 NTACNLASLNLIHFVDEESGHVKINELRHAAALWTVVLEISVLMAHFPSPDIARLSYEYR 891 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 +G+G L +++ +PY+SP+A+ + T A S E++ Sbjct: 892 TLGLGFANLGTVLMVLGIPYDSPKALALAGAISAIITGQAYVTSAEIS 939 >UniRef50_Q3SMN2 Cluster: Ribonucleoside-diphosphate reductase alpha chain; n=1; Thiobacillus denitrificans ATCC 25259|Rep: Ribonucleoside-diphosphate reductase alpha chain - Thiobacillus denitrificans (strain ATCC 25259) Length = 600 Score = 49.6 bits (113), Expect = 7e-05 Identities = 33/109 (30%), Positives = 56/109 (51%), Gaps = 5/109 (4%) Frame = +3 Query: 261 CNLASIALNMFV----DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVP-EAKKSNLRH 425 C+L S+ L FV + + L + L+ +IDV+ YP+ +A+++ + Sbjct: 301 CDLGSLNLTAFVVAPFAADARLDLAALGDAAALAVRFLDDVIDVSRYPLQAQAREARFKR 360 Query: 426 RPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 R IG+G+ GLADA +L+ L Y+S A + ++ A AS +LA Sbjct: 361 R-IGLGITGLADALVLLGLDYDSEPARQLAERAMRTVRDAAYRASIDLA 408 Score = 41.9 bits (94), Expect = 0.014 Identities = 20/54 (37%), Positives = 30/54 (55%) Frame = +1 Query: 67 RFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEI 228 R + VRA+ LW+ I+ A +T P +LF D+ NR + T+ +N C EI Sbjct: 240 RVLRTVRARALWQRILRAAYDTAEPGVLFVDTINRDNTLAGRETLTTTNPCGEI 293 >UniRef50_Q1J1T0 Cluster: Ribonucleoside-diphosphate reductase; n=1; Deinococcus geothermalis DSM 11300|Rep: Ribonucleoside-diphosphate reductase - Deinococcus geothermalis (strain DSM 11300) Length = 1010 Score = 49.6 bits (113), Expect = 7e-05 Identities = 25/78 (32%), Positives = 45/78 (57%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 C+L +I L +V N ++F + +T L+ ++DVN + + + + ++ R +G+ Sbjct: 481 CDLGAINLAAYVQ-NSRFDFAAFRADVRTCVRFLDDVLDVNVFALEDNRVASQDLRRLGL 539 Query: 441 GVQGLADAFILMRLPYES 494 GV GLADA I + L Y+S Sbjct: 540 GVMGLADALIKLGLRYDS 557 Score = 35.9 bits (79), Expect = 0.94 Identities = 22/52 (42%), Positives = 27/52 (51%), Gaps = 3/52 (5%) Frame = +1 Query: 82 VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLG---TIKCSNLCTEI 228 V A+ LW I E TG P ++F D N S KNLG I+ +N C EI Sbjct: 422 VPAKWLWDQIAEHAWATGEPGLIFVDRVNEHSALKNLGKRYEIRSTNPCGEI 473 >UniRef50_Q120H3 Cluster: Ribonucleotide reductase large subunit; n=1; Polaromonas sp. JS666|Rep: Ribonucleotide reductase large subunit - Polaromonas sp. (strain JS666 / ATCC BAA-500) Length = 784 Score = 49.6 bits (113), Expect = 7e-05 Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 4/108 (3%) Frame = +3 Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 C L S L FV + T ++F L +V E L+K++D ++P+P+ R Sbjct: 334 CCLGSPNLTRFVSNPFTLMASFDFDGLSKVVAKAVEMLDKVLDKTHWPLPQQASEAANKR 393 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 IG+G GLADA ++ + Y+S + + ++ A AS LA Sbjct: 394 RIGLGHFGLADAMAMLGIRYDSQQGADFAAHVSEVLRDSAYMASVNLA 441 >UniRef50_Q0LX20 Cluster: Ribonucleoside-diphosphate reductase; n=2; Alphaproteobacteria|Rep: Ribonucleoside-diphosphate reductase - Caulobacter sp. K31 Length = 782 Score = 49.2 bits (112), Expect = 9e-05 Identities = 31/105 (29%), Positives = 50/105 (47%) Frame = +3 Query: 264 NLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIG 443 NLA + N F D + +L + +T L+ +ID++ +P+ R +GIG Sbjct: 323 NLARLVDNPFEAD-AALDEDRLGALARTAVRMLDNVIDISRFPLEAQAVEARAKRRLGIG 381 Query: 444 VQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 V GLADA + Y +A+ ++L + A AS LAA+ Sbjct: 382 VTGLADALVFCGARYGDDQAVALTQRWLGVIKREAYRASARLAAE 426 >UniRef50_O55716 Cluster: Ribonucleoside-diphosphate reductase; n=1; Invertebrate iridescent virus 6|Rep: Ribonucleoside-diphosphate reductase - Chilo iridescent virus (CIV) (Insect iridescent virus type 6) Length = 959 Score = 48.4 bits (110), Expect = 2e-04 Identities = 25/69 (36%), Positives = 39/69 (56%), Gaps = 3/69 (4%) Frame = +1 Query: 22 GKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRK--SNQKNLG 195 G + + + + + V A+ LW+ I+E +++TG PY+ F D+CN+ QK G Sbjct: 204 GGNIDDTWNLIDPHTKKITTVGARDLWQRILETRMKTGEPYICFIDTCNKHMYDFQKKKG 263 Query: 196 -TIKCSNLC 219 TIK SNLC Sbjct: 264 LTIKQSNLC 272 >UniRef50_Q6MNP6 Cluster: Vitamin B12-dependent ribonucleotide reductase; n=1; Bdellovibrio bacteriovorus|Rep: Vitamin B12-dependent ribonucleotide reductase - Bdellovibrio bacteriovorus Length = 764 Score = 48.4 bits (110), Expect = 2e-04 Identities = 22/82 (26%), Positives = 42/82 (51%) Frame = +3 Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 + CNLASI L F++D ++F+ +T+ ++D + YP +++ +RP+ Sbjct: 387 SACNLASINLVKFLNDTGDFDFESFIHTARTLFVAQEILVDYSSYPTQRVAQNSHDYRPL 446 Query: 435 GIGVQGLADAFILMRLPYESPE 500 G+G L + + Y+S E Sbjct: 447 GLGFANLGSLLMRKGVAYDSDE 468 >UniRef50_Q88YQ4 Cluster: Ribonucleoside-diphosphate reductase, alpha chain; n=57; Lactobacillales|Rep: Ribonucleoside-diphosphate reductase, alpha chain - Lactobacillus plantarum Length = 721 Score = 48.0 bits (109), Expect = 2e-04 Identities = 37/145 (25%), Positives = 65/145 (44%), Gaps = 1/145 (0%) Frame = +3 Query: 261 CNLASIAL-NMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437 CNL S + N+ + ++ + + +T++ N +DV VP +K N + IG Sbjct: 409 CNLGSTNIVNLMTSPDFGHSVEAMVRALTFVTDHSN--VDV----VPSIQKGNRQAHTIG 462 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAPA 617 +G GL F ++ Y S EA++ N Y L L+AS E+A + E ++ + Sbjct: 463 LGAMGLHAFFAKNQMEYGSKEAVDFTNIYFLLLNYWTLKASNEIARERHETFVNFEKSKY 522 Query: 618 SRGHITVRHVELKIQPGFMGTGTCF 692 + G ++ QP + T F Sbjct: 523 ADGSYFDKYTTQDWQPKYDKTAALF 547 Score = 36.7 bits (81), Expect = 0.54 Identities = 22/65 (33%), Positives = 39/65 (60%), Gaps = 4/65 (6%) Frame = +1 Query: 79 QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVEYTS----D 246 +++A+ L I + Q E+G PY++ D+ NR++ G I SNLC+E+++ + D Sbjct: 338 KIKARDLENEISKLQQESGYPYVVNIDTANRENPID--GKIVMSNLCSEVMQVQTPSLID 395 Query: 247 DEVQY 261 D+ QY Sbjct: 396 DQQQY 400 >UniRef50_A5JBG3 Cluster: Ribonucleotide reductase, large subunit; n=11; Burkholderia|Rep: Ribonucleotide reductase, large subunit - Burkholderia mallei FMH Length = 677 Score = 48.0 bits (109), Expect = 2e-04 Identities = 28/89 (31%), Positives = 42/89 (47%) Frame = +3 Query: 312 YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYE 491 ++F + L+ +DV +P+ + + + R IG+GV GLAD +MRL Y+ Sbjct: 407 FDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYD 466 Query: 492 SPEAIN*INKYLKLFTMGALEASCELAAK 578 SP A A AS ELAA+ Sbjct: 467 SPAAREMARYIASDLRHHAYAASAELAAE 495 >UniRef50_UPI00004BA6C5 Cluster: UPI00004BA6C5 related cluster; n=1; unknown|Rep: UPI00004BA6C5 UniRef100 entry - unknown Length = 969 Score = 47.6 bits (108), Expect = 3e-04 Identities = 20/55 (36%), Positives = 33/55 (60%) Frame = +1 Query: 55 EKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219 E EN ++ A+ + I + Q+++G PY+++KD+ N+ LG IK SNLC Sbjct: 324 ENENVIKHKINAREMLNLIAQIQLQSGYPYIMYKDNANKNHALNELGEIKMSNLC 378 Score = 38.7 bits (86), Expect = 0.13 Identities = 28/108 (25%), Positives = 54/108 (50%), Gaps = 1/108 (0%) Frame = +3 Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYP-VPEAKKSNLRHRPI 434 +CNLAS LNM K+ K+++E +T L + + + +P K+N +R + Sbjct: 788 ICNLAS--LNMV----KSIEEKEIEESIRTGMRALTFVANNSRIEHLPTVHKANKNNRAV 841 Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAK 578 G+GV ++ Y S E+++ +N Y + +L+ S ++A + Sbjct: 842 GLGVMSFHSMCAKNKIRYGSEESLDLLNVYCMMMDYYSLDESMKIAVE 889 >UniRef50_Q196Z5 Cluster: Ribonucleoside-diphosphate reductase; n=1; Aedes taeniorhynchus iridescent virus|Rep: Ribonucleoside-diphosphate reductase - Aedes taeniorhynchus iridescent virus Length = 630 Score = 47.6 bits (108), Expect = 3e-04 Identities = 26/58 (44%), Positives = 38/58 (65%), Gaps = 3/58 (5%) Frame = +1 Query: 82 VRAQVLWKAIIEAQVETGTPYMLFKDSCNR--KSNQKNLG-TIKCSNLCTEIVEYTSD 246 ++A LW+ II + ETG PY+ + D+ NR QKNLG +I+ SNLC+E+V T + Sbjct: 271 IKATELWERIILTRAETGEPYIHWIDTSNRALPQFQKNLGLSIRQSNLCSEVVLPTDE 328 >UniRef50_A4WLF4 Cluster: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; n=1; Pyrobaculum arsenaticum DSM 13514|Rep: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent - Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321) Length = 1240 Score = 47.6 bits (108), Expect = 3e-04 Identities = 35/115 (30%), Positives = 53/115 (46%), Gaps = 10/115 (8%) Frame = +3 Query: 258 VCNLASIALNMFVDDN----------KTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAK 407 VCNL I L FV DN ++ L + + T L+ ID + + Sbjct: 842 VCNLTHINLVKFVKDNCGGGSFEEKLGCIDWDGLAQAARVGTRFLDDAIDRSKTGIEVID 901 Query: 408 KSNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 + N R G+G+ G A+ I + +PY S EA+ IN+ + + AL+ S ELA Sbjct: 902 EMNAATRKNGLGIMGFAELLIKLGVPYASWEAVELINRIMGWIYVNALDESAELA 956 >UniRef50_Q9RRW1 Cluster: Ribonucleoside-diphosphate reductase; n=1; Deinococcus radiodurans|Rep: Ribonucleoside-diphosphate reductase - Deinococcus radiodurans Length = 1418 Score = 46.4 bits (105), Expect = 7e-04 Identities = 24/78 (30%), Positives = 45/78 (57%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 C+L +I L +V + ++F + +T L+ ++DVN + + + + ++ R +G+ Sbjct: 902 CDLGAINLAAYVRGSD-FDFAAFRADVRTCVRFLDDVLDVNVFALEDNRVASQDLRRLGL 960 Query: 441 GVQGLADAFILMRLPYES 494 GV GLADA I M L Y++ Sbjct: 961 GVMGLADALIKMGLRYDN 978 >UniRef50_Q604J6 Cluster: Ribonucleoside-diphosphate reductase; n=3; Proteobacteria|Rep: Ribonucleoside-diphosphate reductase - Methylococcus capsulatus Length = 1317 Score = 46.0 bits (104), Expect = 9e-04 Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 4/85 (4%) Frame = +3 Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 C L S+ L FV T + ++L EV L+ ++D Y+P+ ++ R Sbjct: 674 CCLGSLDLTRFVSRPFTPEAAFEAERLAEVATIAVRMLDNVLDTTYWPLARQRQEAQAKR 733 Query: 429 PIGIGVQGLADAFILMRLPYESPEA 503 IG+G GL DA ++ L Y+S A Sbjct: 734 RIGLGFTGLGDALAMLGLRYDSAAA 758 >UniRef50_Q8ZTP7 Cluster: Ribonucleoside-diphosphate reductase; n=3; Pyrobaculum|Rep: Ribonucleoside-diphosphate reductase - Pyrobaculum aerophilum Length = 849 Score = 45.2 bits (102), Expect = 0.002 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 10/115 (8%) Frame = +3 Query: 258 VCNLASIALNMFVDDNKT----------YNFKKLKEVTKTITENLNKIIDVNYYPVPEAK 407 VCNL I L FV +N +++ L + + T L+ I+ + + Sbjct: 451 VCNLTHINLVKFVKENCAGGSFEEKLGCIDWEGLAQAARVGTRYLDDAIERSRTGIKIID 510 Query: 408 KSNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 + N R G+G+ G A+ I + +PY S EA+ IN+ + + AL+ S ELA Sbjct: 511 EMNSATRKNGLGIMGFAELLIKLGIPYASWEAVELINRIMGWIYVNALDESAELA 565 >UniRef50_P78027 Cluster: Ribonucleoside-diphosphate reductase subunit alpha; n=36; Firmicutes|Rep: Ribonucleoside-diphosphate reductase subunit alpha - Mycoplasma pneumoniae Length = 721 Score = 45.2 bits (102), Expect = 0.002 Identities = 24/76 (31%), Positives = 40/76 (52%) Frame = +1 Query: 34 ESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSN 213 E YE + + A+ ++ + E E+G PY+LF D+ NR++ N I SN Sbjct: 327 EMYYELLANQRIKKTFINARKFFQTVAELHFESGYPYILFDDTVNRRNAHPN--RIVMSN 384 Query: 214 LCTEIVEYTSDDEVQY 261 LC+EIV+ ++ E + Sbjct: 385 LCSEIVQPSTPSEFHH 400 Score = 42.3 bits (95), Expect = 0.011 Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 1/105 (0%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDV-NYYPVPEAKKSNLRHRPIG 437 CNL S+ + ++ ++ E+ K E+L+ + V N P +K N + +G Sbjct: 413 CNLGSLNIAKAMESGPEFS-----ELVKLAIESLDLVSRVSNLETAPSIQKGNSENHALG 467 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 +G L ++ Y SPEAI+ N + A +AS ELA Sbjct: 468 LGAMNLHGFLATNQIYYNSPEAIDFTNIFFYTVAYHAFKASSELA 512 >UniRef50_A7CVZ3 Cluster: Ribonucleoside-diphosphate reductase precursor; n=1; Opitutaceae bacterium TAV2|Rep: Ribonucleoside-diphosphate reductase precursor - Opitutaceae bacterium TAV2 Length = 613 Score = 44.8 bits (101), Expect = 0.002 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 4/69 (5%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEK---ENRFVX-QVRAQVLWKAIIEAQVETGTPYMLFKDSCN 168 P L + +G++FE Y YE E + ++ A LWK ++ ETG ++ FKD+CN Sbjct: 544 PDLHELYGRKFEDAYLRYETLAAEGKIHGHRIAALDLWKKMLSMLFETGHTWLTFKDACN 603 Query: 169 RKSNQKNLG 195 +S Q + G Sbjct: 604 IRSPQDHAG 612 >UniRef50_A1W357 Cluster: Ribonucleoside-diphosphate reductase; n=16; Burkholderiales|Rep: Ribonucleoside-diphosphate reductase - Acidovorax sp. (strain JS42) Length = 811 Score = 44.8 bits (101), Expect = 0.002 Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 6/110 (5%) Frame = +3 Query: 261 CNLASIALNMFVDD------NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422 C+L I L FV + +++F ++ T L+ ++DV ++P+P+ + + Sbjct: 308 CDLGPIILTRFVRNPFGLHGEASFDFDAFEQAVATQVRALDNVLDVTFWPLPQQQAESAA 367 Query: 423 HRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 R IG+G G+ + ++ Y+ E + + + A AS ELA Sbjct: 368 KRRIGVGFTGMGNTLAMLCKRYDRQEGRDMAVQIAERMRNAAYRASVELA 417 Score = 35.1 bits (77), Expect = 1.6 Identities = 17/48 (35%), Positives = 26/48 (54%) Frame = +1 Query: 82 VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 VRA+ LW I+++ + P +LF D N +N TI+ +N C E Sbjct: 252 VRARELWDTIMKSAYDFAEPGILFLDQINTDNNLHYTETIQATNPCGE 299 >UniRef50_A1TJY2 Cluster: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; n=3; Comamonadaceae|Rep: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent - Acidovorax avenae subsp. citrulli (strain AAC00-1) Length = 1226 Score = 44.4 bits (100), Expect = 0.003 Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 6/110 (5%) Frame = +3 Query: 261 CNLASIALNMFVDD------NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLR 422 C+L I L FV ++F T L+ ++DV ++P+P+ + + Sbjct: 701 CDLGPIILPRFVRHPFGFAGEPAFDFDAFAASVATQVRALDNVLDVTFWPLPQQRAESAA 760 Query: 423 HRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 R IG+G GL + ++RL Y++ + + A AS ELA Sbjct: 761 KRRIGVGFTGLGNTLAMLRLRYDTDAGRAMAMRIAECMRDAAYAASVELA 810 >UniRef50_P0A5W9 Cluster: Ribonucleoside-diphosphate reductase subunit alpha; n=110; Bacteria|Rep: Ribonucleoside-diphosphate reductase subunit alpha - Mycobacterium bovis Length = 725 Score = 44.4 bits (100), Expect = 0.003 Identities = 23/70 (32%), Positives = 43/70 (61%) Frame = +1 Query: 34 ESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSN 213 E YE + +++A+ ++ + E Q E+G PY++F+D+ NR +N + G I SN Sbjct: 340 EKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNR-ANPID-GKITHSN 397 Query: 214 LCTEIVEYTS 243 LC+EI++ ++ Sbjct: 398 LCSEILQVST 407 >UniRef50_Q2S5T5 Cluster: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; n=1; Salinibacter ruber DSM 13855|Rep: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent - Salinibacter ruber (strain DSM 13855) Length = 894 Score = 44.0 bits (99), Expect = 0.004 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 1/106 (0%) Frame = +3 Query: 258 VCNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 VC L ++ + VD + T ++ + ++ L+ + D++Y P+ E +++ R I Sbjct: 373 VCLLGNLNVTQLVDREAGTIDYDLVDDLVPLAVRFLDNVNDLSYVPLEEQQRNLQEKRRI 432 Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 G+G G A ++M+ Y S E + ++ + A +AS LA Sbjct: 433 GLGHYGDGSALMMMKTRYGSEEGARVMREFQEHLANQAYQASARLA 478 >UniRef50_P03190 Cluster: Ribonucleoside-diphosphate reductase large chain; n=5; Lymphocryptovirus|Rep: Ribonucleoside-diphosphate reductase large chain - Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4) Length = 826 Score = 44.0 bits (99), Expect = 0.004 Identities = 21/73 (28%), Positives = 40/73 (54%), Gaps = 1/73 (1%) Frame = +1 Query: 19 WGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLG- 195 +G+EFE Y +F +V + L +I+ V+ G+P++L K++CN + G Sbjct: 322 YGEEFEREYYRLVTAGKFCGRVSIKSLMFSIVNCAVKAGSPFILLKEACNAHFWRDLQGE 381 Query: 196 TIKCSNLCTEIVE 234 + +NLC E+++ Sbjct: 382 AMNAANLCAEVLQ 394 >UniRef50_Q9HPG8 Cluster: Ribonucleoside-diphosphate reductase; n=5; root|Rep: Ribonucleoside-diphosphate reductase - Halobacterium salinarium (Halobacterium halobium) Length = 1051 Score = 42.3 bits (95), Expect = 0.011 Identities = 23/74 (31%), Positives = 39/74 (52%) Frame = +3 Query: 351 TENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEAIN*INKYLK 530 T L ++ ++ +PVPE ++ R IG+GV GLA +I + + Y S E ++ ++ Sbjct: 499 TRFLENVVTMSDFPVPEIEQKVSEMRKIGLGVMGLAQLYIQLGVKYGSEEGNEIASQLMQ 558 Query: 531 LFTMGALEASCELA 572 + AS ELA Sbjct: 559 TINHDSKTASHELA 572 >UniRef50_Q5DN91 Cluster: Ribonucleotide reductase; n=1; Phage phiJL001|Rep: Ribonucleotide reductase - Phage phiJL001 Length = 602 Score = 41.9 bits (94), Expect = 0.014 Identities = 24/92 (26%), Positives = 44/92 (47%) Frame = +3 Query: 297 DDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILM 476 D T+++ + ++ ++D YP+ E +K R +G+GV LA+A + Sbjct: 319 DSRWTFDWDLFATDVYAVVRAMDNVVDRAIYPLFEQEKEAKSKRRMGLGVTALANAAEAL 378 Query: 477 RLPYESPEAIN*INKYLKLFTMGALEASCELA 572 +PY S E + + L+ + +AS ELA Sbjct: 379 GMPYGSIEFLKFEGQVLETLACNSYQASVELA 410 Score = 34.7 bits (76), Expect = 2.2 Identities = 17/48 (35%), Positives = 25/48 (52%) Frame = +1 Query: 82 VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 + A+ LW+ I+ + + P LF D NR +N K TI +N C E Sbjct: 239 INAENLWEMIMRSTWDWAEPGTLFIDQINRMNNLKYCETIAATNPCGE 286 >UniRef50_Q2NME4 Cluster: Ribonucleoside-diphosphate reductase large chain; n=2; unclassified Iridovirus|Rep: Ribonucleoside-diphosphate reductase large chain - Costelytra zealandica iridescent virus (CzIV) (Insect iridescent virustype 16) Length = 378 Score = 41.5 bits (93), Expect = 0.019 Identities = 28/74 (37%), Positives = 40/74 (54%), Gaps = 4/74 (5%) Frame = +1 Query: 10 ADCWGKEFESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRK--SN 180 A + KE + ++ + N+ V + + A LW+ I+ + E G PY F D+ NRK Sbjct: 90 AQTYIKEMDK-FDLTDPHNKEVKETISATELWERILVTRAECGEPYCHFIDTSNRKLPEF 148 Query: 181 QKNLG-TIKCSNLC 219 QK LG IK SNLC Sbjct: 149 QKKLGLNIKQSNLC 162 >UniRef50_P50620 Cluster: Ribonucleoside-diphosphate reductase subunit alpha; n=53; Bacteria|Rep: Ribonucleoside-diphosphate reductase subunit alpha - Bacillus subtilis Length = 700 Score = 41.5 bits (93), Expect = 0.019 Identities = 31/137 (22%), Positives = 64/137 (46%) Frame = +3 Query: 261 CNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGI 440 CNL S+ + + V ++K+ K +K T ++T ++++ D+ P +++N + IG+ Sbjct: 409 CNLGSLNI-LNVMEHKSIE-KTVKLATDSLT-HVSETTDIRN--APAVRRANKAMKSIGL 463 Query: 441 GVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAPAS 620 G L + YESPEA + N + + +++ S E+A + E + + Sbjct: 464 GAMNLHGYLAQNGIAYESPEARDFANTFFMMVNFYSIQRSAEIAKEKGETFDQYEGSTYA 523 Query: 621 RGHITVRHVELKIQPGF 671 G ++V P + Sbjct: 524 TGEYFDKYVSTDFSPKY 540 Score = 39.5 bits (88), Expect = 0.076 Identities = 16/70 (22%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Frame = +1 Query: 28 EFESLYETYEKENRFVXQ-VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIK 204 + +Y+ + R + + + L + + + E+G PY++F+D+ N+ ++ +K Sbjct: 318 DMNEMYDKFVDNPRVKKEKINPRKLLEKLAMLRSESGYPYIMFQDNVNKVHANNHISKVK 377 Query: 205 CSNLCTEIVE 234 SNLC+E+++ Sbjct: 378 FSNLCSEVLQ 387 >UniRef50_O41962 Cluster: Ribonucleoside-diphosphate reductase; n=2; Murid herpesvirus 4|Rep: Ribonucleoside-diphosphate reductase - Murid herpesvirus 4 (MuHV-4) (Murine gammaherpesvirus 68) Length = 783 Score = 41.1 bits (92), Expect = 0.025 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 4/85 (4%) Frame = +1 Query: 7 LADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKS--- 177 L + +G F Y ++ + V + + A++ ++TG PY+L K + NR Sbjct: 326 LTNTYGYMFSIAYAGLVEQGAYEAVVPIKSVMFALVSCIIKTGGPYILNKKAINRHDWHE 385 Query: 178 -NQKNLGTIKCSNLCTEIVEYTSDD 249 + I C+NLC E+++Y ++ Sbjct: 386 WSTHQYRAINCANLCAEVIQYPGEN 410 Score = 41.1 bits (92), Expect = 0.025 Identities = 30/91 (32%), Positives = 45/91 (49%), Gaps = 13/91 (14%) Frame = +3 Query: 255 AVCNLASIALNMFVDDNK---------TY----NFKKLKEVTKTITENLNKIIDVNYYPV 395 + CNLA+I L ++D+K TY + ++L+ T+ +N I P Sbjct: 412 STCNLANICLPKCLEDDKFVSGKSCLLTYEREFSIERLERATEAAVFIINACIHGGTLPT 471 Query: 396 PEAKKSNLRHRPIGIGVQGLADAFILMRLPY 488 A++ R +GIGVQGLAD F +M L Y Sbjct: 472 QRARRGQ-SDRSMGIGVQGLADTFAMMGLGY 501 >UniRef50_A5FCJ4 Cluster: Ribonucleoside-diphosphate reductase, alpha chain; n=2; cellular organisms|Rep: Ribonucleoside-diphosphate reductase, alpha chain - Flavobacterium johnsoniae UW101 Length = 565 Score = 40.7 bits (91), Expect = 0.033 Identities = 20/56 (35%), Positives = 34/56 (60%), Gaps = 4/56 (7%) Frame = +1 Query: 97 LWKAIIEAQVETGTPYMLFKDSCNRKSNQ----KNLGTIKCSNLCTEIVEYTSDDE 252 +W ++E++ + G PY+ F D+ N+ Q +NL I SNLC+EI+ ++ DE Sbjct: 223 IWAKVLESRQQKGLPYIFFSDNVNKNKPQVYKDQNL-RINASNLCSEIMLPSTHDE 277 Score = 37.1 bits (82), Expect = 0.41 Identities = 30/107 (28%), Positives = 48/107 (44%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRP 431 S +C L+S+ L ++ + T K + + + + NYY + A K RHR Sbjct: 278 SFICCLSSMNLELYEEWKDTEAVKLAIFFLDAVLQEFIEKTEGNYY-LSAANKFAKRHRA 336 Query: 432 IGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 +G+GV G +P+E EA + K + A +AS ELA Sbjct: 337 LGLGVLGWHSYLQKNMIPFEGMEAKMKTTEIFKHISDKADKASQELA 383 >UniRef50_Q5A0N2 Cluster: Putative uncharacterized protein; n=1; Candida albicans|Rep: Putative uncharacterized protein - Candida albicans (Yeast) Length = 135 Score = 40.7 bits (91), Expect = 0.033 Identities = 28/77 (36%), Positives = 37/77 (48%) Frame = +2 Query: 29 NLNPYMKHMKKKIDLXNK*GHKFFGKQ**KLK*RLVLHTCYLKIHVIEKVIRKI*VP*NV 208 N Y + KKK + K G + K + V H CY+KIHV ++ V N+ Sbjct: 22 NSKNYTPNTKKKTVVDRPSKLKNCGMLFWEPKSKQVPHLCYIKIHVTTNPTKRTWVLSNL 81 Query: 209 VTCALK*LNIHLMMKCS 259 TC +K LNI L MK S Sbjct: 82 PTCVVKLLNISLQMKLS 98 >UniRef50_O41114 Cluster: A632L protein; n=1; Paramecium bursaria Chlorella virus 1|Rep: A632L protein - Paramecium bursaria Chlorella virus 1 (PBCV-1) Length = 72 Score = 40.3 bits (90), Expect = 0.044 Identities = 25/57 (43%), Positives = 28/57 (49%) Frame = -2 Query: 251 SSSDVYSTISVHRLLHFMVPKXXXXXXXLHESLNNMYGVPVST*ASIIAFQRTCALT 81 SS DVYS IS+H+LL MVP SL YG PVS I F + A T Sbjct: 7 SSFDVYSRISIHKLLPRMVPALDCIFFLFTVSLLATYGCPVSMMVVTIVFHTSRAFT 63 >UniRef50_Q897Z5 Cluster: Ribonucleoside-diphosphate reductase; n=2; Clostridium|Rep: Ribonucleoside-diphosphate reductase - Clostridium tetani Length = 1047 Score = 40.3 bits (90), Expect = 0.044 Identities = 26/94 (27%), Positives = 40/94 (42%), Gaps = 1/94 (1%) Frame = +3 Query: 261 CNLASIALNMFVDDN-KTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437 CNLASI + F D K + + V + L I +P + + R G Sbjct: 422 CNLASINIYKFYDGKEKNIDLESYLHVVGLVQLALEASIYWGQFPTKDIAQKTYMFRATG 481 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFT 539 +G+ LA +++ PY S EA N + + L T Sbjct: 482 LGITNLASLLMVLGYPYNSTEARNISSALVGLLT 515 >UniRef50_A0LDD1 Cluster: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; n=24; Proteobacteria|Rep: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent - Magnetococcus sp. (strain MC-1) Length = 707 Score = 40.3 bits (90), Expect = 0.044 Identities = 24/108 (22%), Positives = 48/108 (44%), Gaps = 4/108 (3%) Frame = +3 Query: 261 CNLASIALNMFVDDNKT----YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 C L S+ L FV + T +++ + KEV T L+ +++++ P+P R Sbjct: 329 CLLGSVNLARFVKNPFTAKAEFDWARFKEVVAVFTRMLDNVVEIHGLPLPGQADEIAHKR 388 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELA 572 G+G GL ++ + Y +++ ++ + + E ELA Sbjct: 389 RHGMGFLGLGSTLTMLNMVYGDRQSVEFTSQVAREMALTGWEVGLELA 436 >UniRef50_P37426 Cluster: Ribonucleoside-diphosphate reductase 1 subunit alpha; n=194; root|Rep: Ribonucleoside-diphosphate reductase 1 subunit alpha - Salmonella typhimurium Length = 761 Score = 40.3 bits (90), Expect = 0.044 Identities = 32/112 (28%), Positives = 50/112 (44%) Frame = +3 Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 A+C L++ L KT + +L+E+ L+ ++D YP+P AK+ + R + Sbjct: 460 ALCTLSAFNLGAI----KTLD--ELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTL 513 Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWEC 590 GIGV A Y A N +K + L+AS ELA + C Sbjct: 514 GIGVINFAYWLAKNGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGAC 565 >UniRef50_Q8SCB8 Cluster: Large subunit ribonucleotide reductase; n=7; unclassified Myoviridae|Rep: Large subunit ribonucleotide reductase - Staphylococcus phage Twort Length = 705 Score = 39.9 bits (89), Expect = 0.058 Identities = 16/42 (38%), Positives = 25/42 (59%) Frame = +1 Query: 109 IIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVE 234 I Q+E+G PY+ + D+ N K LG ++ SNLC E+ + Sbjct: 347 IARTQLESGYPYVFYIDNANDNHPLKKLGKVQMSNLCCEVTQ 388 Score = 35.9 bits (79), Expect = 0.94 Identities = 31/137 (22%), Positives = 58/137 (42%), Gaps = 1/137 (0%) Frame = +3 Query: 258 VCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYP-VPEAKKSNLRHRPI 434 VC L S+ L V+ LKE + +L+K+ D+ P +P +K+N R I Sbjct: 411 VCTLGSLNLVNVVEKGL------LKESVDSGIRSLSKVTDLMNVPFLPSVQKANDELRAI 464 Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAP 614 G+G L Y S E+++ N ++++S ELA + + ++ Sbjct: 465 GLGAMNWHGLLAKNMLSYGSRESLDIANSLFSAIRYYSIKSSMELAKETGKVFKGFKESE 524 Query: 615 ASRGHITVRHVELKIQP 665 G + +++ +P Sbjct: 525 YYTGEVFSSYIQKSHEP 541 >UniRef50_Q66LW9 Cluster: Ribonucleoside-diphosphate reductase 1 alpha chain; n=3; Enterobacteria phage T5|Rep: Ribonucleoside-diphosphate reductase 1 alpha chain - Bacteriophage T5 Length = 811 Score = 39.9 bits (89), Expect = 0.058 Identities = 30/128 (23%), Positives = 58/128 (45%) Frame = +3 Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 ++CNL + L + + + ++ + + ++ II++ YP P + + + R + Sbjct: 514 SLCNLGGVVLG------RMESLAEWEKTCYILLKFVDTIIEIQDYPFPTMEYTAKKRRNV 567 Query: 435 GIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWECMIHTTDAP 614 GIG+ A A L YE EA N I++ + + +AS LA + C P Sbjct: 568 GIGLMNAAGAMAAEGLAYEGIEARNWIHREAEKLSYFLHKASVRLAKEQGACEWFNRTKP 627 Query: 615 ASRGHITV 638 S+G + + Sbjct: 628 -SKGILVI 634 >UniRef50_Q6YRG1 Cluster: Ribonucleoside-diphosphate reductase; n=4; Candidatus Phytoplasma|Rep: Ribonucleoside-diphosphate reductase - Onion yellows phytoplasma Length = 769 Score = 39.1 bits (87), Expect = 0.10 Identities = 21/53 (39%), Positives = 34/53 (64%) Frame = +1 Query: 82 VRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTEIVEYT 240 + + L + I Q E+G PY++F D+ N ++N +L +K SNLCTEI++ T Sbjct: 409 INPRQLLELIAHMQGESGYPYLMFCDNTN-QANTSDL-KVKFSNLCTEILQPT 459 >UniRef50_Q1ISM3 Cluster: Ribonucleoside-diphosphate reductase; n=2; Bacteria|Rep: Ribonucleoside-diphosphate reductase - Acidobacteria bacterium (strain Ellin345) Length = 1004 Score = 39.1 bits (87), Expect = 0.10 Identities = 22/80 (27%), Positives = 36/80 (45%) Frame = +3 Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 + CNLAS+ L F N T++ + ++D YP K++ +RP+ Sbjct: 410 SACNLASLNLMKFAP-NGTFDVAAYRHACAITITAQEILVDNAGYPTESIMKNSHDYRPL 468 Query: 435 GIGVQGLADAFILMRLPYES 494 G+G L + LPY+S Sbjct: 469 GLGYANLGALLMAAGLPYDS 488 Score = 32.7 bits (71), Expect = 8.8 Identities = 19/56 (33%), Positives = 25/56 (44%) Frame = +1 Query: 58 KENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 K V +A+ L I EA + G P M + + NR KN I SN C+E Sbjct: 348 KSGDVVKTFKARWLLSKISEATWQCGDPGMQYDTTVNRWHTSKNTARINASNPCSE 403 >UniRef50_Q0W4L0 Cluster: Putative uncharacterized protein; n=2; uncultured methanogenic archaeon RC-I|Rep: Putative uncharacterized protein - Uncultured methanogenic archaeon RC-I Length = 269 Score = 38.7 bits (86), Expect = 0.13 Identities = 30/77 (38%), Positives = 38/77 (49%), Gaps = 6/77 (7%) Frame = -3 Query: 370 ILFKFSVIVLVTSFNFLKL-YVL-LSSTNIFSAIEAKLHTALHHQMYIQLFQCTGYYILW 197 I F VL FN L L +VL LSST F ++ + TAL QM C + IL+ Sbjct: 131 IYFNDPTEVLPVIFNILPLMFVLSLSSTMFFYSLTLLICTALKDQMLSFFTSCLSWIILF 190 Query: 196 YLN----FSDYFFYYMN 158 YL F+ Y YY+N Sbjct: 191 YLINDDWFAGYISYYLN 207 >UniRef50_O55567 Cluster: P25; n=1; Leucania separata nuclear polyhedrosis virus|Rep: P25 - Leucania separata nuclear polyhedrosis virus (LsNPV) Length = 222 Score = 38.3 bits (85), Expect = 0.18 Identities = 19/44 (43%), Positives = 26/44 (59%) Frame = +1 Query: 1 PGLADCWGKEFESLYETYEKENRFVXQVRAQVLWKAIIEAQVET 132 P L D +G +FE Y+ YE + +F Q+ A L + IIE Q ET Sbjct: 158 PKLNDTYGDDFEYWYKHYEDKGQFREQMPAVTLMRNIIEIQAET 201 >UniRef50_A7HCF4 Cluster: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; n=3; Cystobacterineae|Rep: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent - Anaeromyxobacter sp. Fw109-5 Length = 929 Score = 37.9 bits (84), Expect = 0.23 Identities = 20/80 (25%), Positives = 36/80 (45%) Frame = +3 Query: 255 AVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPI 434 + CNLAS+ L F + ++ + K ++ YP + K++ +RP+ Sbjct: 377 SACNLASLNLMHFRGIDGAFDVESFKRAVDLTVLAQEILVSNAKYPTEQIGKNSEDYRPL 436 Query: 435 GIGVQGLADAFILMRLPYES 494 G+G L + LPY+S Sbjct: 437 GLGYANLGALLMASGLPYDS 456 >UniRef50_UPI000155442E Cluster: hypothetical protein ORF046; n=1; Pseudomonas phage M6|Rep: hypothetical protein ORF046 - Pseudomonas phage M6 Length = 620 Score = 37.1 bits (82), Expect = 0.41 Identities = 16/62 (25%), Positives = 34/62 (54%) Frame = +3 Query: 312 YNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYE 491 +++ + +E + ++ ++D YP+P+ K+ R +G+G+ GLA+A + Y Sbjct: 335 FDWDQYREDIPQVVRAMDNVVDRAIYPLPQQKQEAKDKRRMGLGITGLANAAEALGHEYG 394 Query: 492 SP 497 SP Sbjct: 395 SP 396 Score = 34.7 bits (76), Expect = 2.2 Identities = 18/49 (36%), Positives = 26/49 (53%) Frame = +1 Query: 79 QVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLCTE 225 +V A+ LW AI+ + P +LF D+ NR +N TI +N C E Sbjct: 257 EVDARALWDAIMRGTWDWAEPGVLFIDAINRMNNLWYCETIAATNPCGE 305 >UniRef50_A3XHF8 Cluster: Ribonucleoside-diphosphate reductase, alpha subunit 1; n=10; root|Rep: Ribonucleoside-diphosphate reductase, alpha subunit 1 - Leeuwenhoekiella blandensis MED217 Length = 600 Score = 36.7 bits (81), Expect = 0.54 Identities = 19/54 (35%), Positives = 32/54 (59%), Gaps = 3/54 (5%) Frame = +1 Query: 97 LWKAIIEAQVETGTPYMLFKDSCN--RKSNQKNLG-TIKCSNLCTEIVEYTSDD 249 +W +++ + E G PY+ + D+ N + K+ G I SNLCTEI+ +SD+ Sbjct: 247 VWAKVLQRRGEMGYPYIFYTDNANNGKPDVYKDKGHDIYASNLCTEIMLPSSDE 300 >UniRef50_Q6LQZ0 Cluster: Putative uncharacterized protein; n=2; Photobacterium profundum|Rep: Putative uncharacterized protein - Photobacterium profundum (Photobacterium sp. (strain SS9)) Length = 173 Score = 35.9 bits (79), Expect = 0.94 Identities = 19/61 (31%), Positives = 31/61 (50%) Frame = +1 Query: 28 EFESLYETYEKENRFVXQVRAQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKC 207 +F++LYE E V + + KA + AQ GTPY LF +C + Q + ++C Sbjct: 42 QFDTLYEFSEGRAILVSSITSDEPEKAYLYAQQYLGTPYNLFNRNCEQFVRQSHGLPVEC 101 Query: 208 S 210 + Sbjct: 102 T 102 >UniRef50_Q7TDH5 Cluster: Ribonucleoside-diphosphate reductase; n=2; Haloviruses|Rep: Ribonucleoside-diphosphate reductase - Halovirus HF1 Length = 805 Score = 35.1 bits (77), Expect = 1.6 Identities = 16/63 (25%), Positives = 32/63 (50%) Frame = +3 Query: 315 NFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYES 494 +F +L + T L+ ++ + +P+PE + R IG+G+ G A M +PY + Sbjct: 433 DFNELDRTIEAGTRFLDNVVTQSDFPIPEITERVGGMRKIGLGIMGFAQMLYQMGVPYGT 492 Query: 495 PEA 503 ++ Sbjct: 493 QDS 495 >UniRef50_Q18GD3 Cluster: Ribonucleoside-diphosphate reductase alpha subunit; n=1; Haloquadratum walsbyi DSM 16790|Rep: Ribonucleoside-diphosphate reductase alpha subunit - Haloquadratum walsbyi (strain DSM 16790) Length = 1909 Score = 35.1 bits (77), Expect = 1.6 Identities = 17/51 (33%), Positives = 29/51 (56%) Frame = +3 Query: 351 TENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFILMRLPYESPEA 503 T L ++ ++ +PV E + + R IG+G+ GLA +I + + Y S EA Sbjct: 910 TRFLENVVTMSDFPVDEIEATVRDMRKIGLGIMGLAQLYIQIGVRYGSQEA 960 >UniRef50_O31875 Cluster: Ribonucleoside-diphosphate reductase; n=13; root|Rep: Ribonucleoside-diphosphate reductase - Bacillus subtilis Length = 1084 Score = 34.7 bits (76), Expect = 2.2 Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 1/110 (0%) Frame = +3 Query: 261 CNLASIAL-NMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437 CNL S+ + N+ + + + + T+T N I++ P ++N R IG Sbjct: 793 CNLGSMNIVNVMSNQSIASTVRIAIDSLTTVTRKTN-IVNA-----PAVARANTLMRSIG 846 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKVWE 587 +G L + YES EA + N Y + +L+ S E+A + E Sbjct: 847 LGQMNLHGFLAQNNIAYESEEAKDFANTYFMMVNFYSLQRSMEIARETGE 896 Score = 33.9 bits (74), Expect = 3.8 Identities = 14/44 (31%), Positives = 27/44 (61%) Frame = +1 Query: 88 AQVLWKAIIEAQVETGTPYMLFKDSCNRKSNQKNLGTIKCSNLC 219 A+ L + + + E+G PY++F D+ N+ +++ +K SNLC Sbjct: 338 ARKLLEQLAILRSESGYPYIMFADNVNKVHPNEHISKVKFSNLC 381 >UniRef50_Q5CHN1 Cluster: Putative uncharacterized protein; n=1; Cryptosporidium hominis|Rep: Putative uncharacterized protein - Cryptosporidium hominis Length = 76 Score = 33.9 bits (74), Expect = 3.8 Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 1/54 (1%) Frame = -2 Query: 470 NKSISKTLNTYSNRSMSKIRFFCFR-NRVIIYINDFIQIFCYSFSNFF*FLKVI 312 +K + K Y + ++SK +F + N + I+IN F + +S SNFF FL ++ Sbjct: 23 SKILKKNNRRYLS-NISKKKFVLIKQNNITIHINKFFFLLFFSLSNFFLFLNIV 75 >UniRef50_O69981 Cluster: Vitamin B12-dependent ribonucleotide reductase; n=12; Actinomycetales|Rep: Vitamin B12-dependent ribonucleotide reductase - Streptomyces coelicolor Length = 967 Score = 33.9 bits (74), Expect = 3.8 Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 4/111 (3%) Frame = +3 Query: 261 CNLASIALNMFVDD----NKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHR 428 CNLAS+ L F+ D N++++ ++ +V + + ++ I +P + ++ R Sbjct: 377 CNLASLNLMKFLKDDGKGNQSFDAERFSKVVELVITAMDISICFADFPTQKIGENTRAFR 436 Query: 429 PIGIGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKV 581 +GIG L + Y+S L T + S ELAA V Sbjct: 437 QLGIGYANLGALLMATGHAYDSDGGRALAGAITSLMTGTSYRRSAELAAIV 487 >UniRef50_Q89MB9 Cluster: Vitamin B12-dependent ribonucleotide reductase; n=82; root|Rep: Vitamin B12-dependent ribonucleotide reductase - Bradyrhizobium japonicum Length = 1254 Score = 33.9 bits (74), Expect = 3.8 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 1/108 (0%) Frame = +3 Query: 261 CNLASIALNMFVD-DNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIG 437 CNLAS L F + K ++ + + + + T L + + +P + + R +G Sbjct: 487 CNLASANLLTFYNVATKHFDVEGYEHLCRLWTVVLEISVMMAQFPSKAIAELSYEFRTLG 546 Query: 438 IGVQGLADAFILMRLPYESPEAIN*INKYLKLFTMGALEASCELAAKV 581 +G + + M LPY+S E + T + S E+AA++ Sbjct: 547 LGYANIGGLLMTMGLPYDSKEGRALCGALTAVMTGITYKTSAEIAAEL 594 >UniRef50_Q7RJL4 Cluster: Putative uncharacterized protein PY03245; n=4; Plasmodium (Vinckeia)|Rep: Putative uncharacterized protein PY03245 - Plasmodium yoelii yoelii Length = 409 Score = 33.5 bits (73), Expect = 5.0 Identities = 17/70 (24%), Positives = 34/70 (48%) Frame = +3 Query: 291 FVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSNLRHRPIGIGVQGLADAFI 470 F++DNK Y + K+ E++ + + NLNK Y + L + I + + + +I Sbjct: 139 FIEDNKDYLYNKIGEISNSFSTNLNK------YTTCMHELYGLYNESIDVSMDNFRNGYI 192 Query: 471 LMRLPYESPE 500 M++ + E Sbjct: 193 FMQIHFSKHE 202 >UniRef50_A2FWX8 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 3852 Score = 33.5 bits (73), Expect = 5.0 Identities = 18/44 (40%), Positives = 27/44 (61%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVN 383 SA I LNM + D+ F+K + + KTI+ENL KII+++ Sbjct: 1860 SATLKYPEIPLNMILMDSNYNGFEK-EMIKKTISENLPKIIEIS 1902 >UniRef50_Q7REC9 Cluster: Putative uncharacterized protein PY05136; n=3; Plasmodium (Vinckeia)|Rep: Putative uncharacterized protein PY05136 - Plasmodium yoelii yoelii Length = 368 Score = 33.1 bits (72), Expect = 6.6 Identities = 18/55 (32%), Positives = 30/55 (54%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKKSN 416 S LAS + F D+N + +K++E K ++E++ II P+PEA+ N Sbjct: 309 SVATTLASSFADTFKDENGKPDKRKMQEQGKLMSEHMQHIIKEVSKPLPEAQTKN 363 >UniRef50_A0DYW6 Cluster: Chromosome undetermined scaffold_7, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_7, whole genome shotgun sequence - Paramecium tetraurelia Length = 782 Score = 33.1 bits (72), Expect = 6.6 Identities = 15/49 (30%), Positives = 28/49 (57%) Frame = +3 Query: 264 NLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDVNYYPVPEAKK 410 N S L +F+ ++YN + +++ K IT N+ I+D N PV + ++ Sbjct: 129 NCLSYFLLLFLFKKQSYNLNQAQDIIKQITSNIYVILDNNLNPVYDEER 177 >UniRef50_UPI00006CE942 Cluster: hypothetical repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: hypothetical repeat containing protein - Tetrahymena thermophila SB210 Length = 2307 Score = 32.7 bits (71), Expect = 8.8 Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 2/55 (3%) Frame = +3 Query: 252 SAVCNLASIALNMFVDDNKTYNFKKLKEVTKTITENLNKIIDV--NYYPVPEAKK 410 S C+ ASI + +F+ DN +YN+ +K + K I E L + ID Y P E K+ Sbjct: 2068 STNCSAASILIGVFIYDN-SYNY-LIKGIKKIIIEKLAEKIDYFKKYLPKEEQKR 2120 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 618,219,844 Number of Sequences: 1657284 Number of extensions: 11156924 Number of successful extensions: 32211 Number of sequences better than 10.0: 147 Number of HSP's better than 10.0 without gapping: 30431 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 32039 length of database: 575,637,011 effective HSP length: 98 effective length of database: 413,223,179 effective search space used: 54545459628 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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