Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= prgv0240
(673 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 101 3e-21
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 101 3e-21
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 81 3e-15
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 81 3e-15
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 81 3e-15
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 80 6e-15
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 76 1e-13
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 76 1e-13
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 76 1e-13
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 76 1e-13
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 76 1e-13
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 75 2e-13
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 75 2e-13
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 75 2e-13
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 75 2e-13
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 75 2e-13
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 75 2e-13
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 75 2e-13
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 75 2e-13
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 75 2e-13
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 75 2e-13
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 75 2e-13
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 75 2e-13
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 75 2e-13
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 75 2e-13
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 75 2e-13
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 75 2e-13
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 75 2e-13
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 75 2e-13
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 75 2e-13
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 75 2e-13
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 75 2e-13
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 75 2e-13
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 74 4e-13
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 74 4e-13
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 74 5e-13
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 74 5e-13
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 74 5e-13
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 74 5e-13
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 74 5e-13
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 74 5e-13
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 74 5e-13
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 74 5e-13
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 74 5e-13
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 74 5e-13
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 74 5e-13
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 74 5e-13
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 74 5e-13
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 74 5e-13
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 74 5e-13
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 74 5e-13
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 74 5e-13
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 74 5e-13
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 74 5e-13
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 74 5e-13
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 73 7e-13
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 73 7e-13
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 73 7e-13
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 73 7e-13
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 73 7e-13
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 73 7e-13
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 72 2e-12
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 72 2e-12
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 71 5e-12
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 71 5e-12
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 71 5e-12
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 71 5e-12
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 71 5e-12
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 71 5e-12
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 71 5e-12
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 71 5e-12
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 71 5e-12
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 70 9e-12
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 70 9e-12
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 70 9e-12
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 70 9e-12
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 70 9e-12
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 70 9e-12
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 70 9e-12
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 70 9e-12
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 69 1e-11
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 69 2e-11
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 69 2e-11
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 68 3e-11
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 68 3e-11
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 68 3e-11
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 68 3e-11
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 68 3e-11
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 68 3e-11
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 68 3e-11
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 68 4e-11
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 68 4e-11
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 67 5e-11
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 67 5e-11
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 67 5e-11
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 67 5e-11
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 67 5e-11
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 67 5e-11
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 67 5e-11
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 67 6e-11
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 67 6e-11
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 66 8e-11
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 66 1e-10
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 66 1e-10
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 66 1e-10
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 66 1e-10
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 66 1e-10
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 66 1e-10
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 65 2e-10
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 65 2e-10
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 65 2e-10
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 65 2e-10
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 65 2e-10
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 65 2e-10
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 65 2e-10
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 65 2e-10
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 65 2e-10
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 64 3e-10
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 64 4e-10
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 64 4e-10
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 64 4e-10
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 64 4e-10
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 64 4e-10
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 64 4e-10
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 64 4e-10
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 64 4e-10
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 64 4e-10
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 63 1e-09
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 63 1e-09
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 63 1e-09
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 63 1e-09
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 63 1e-09
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 63 1e-09
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 63 1e-09
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 63 1e-09
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 63 1e-09
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 63 1e-09
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 63 1e-09
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 63 1e-09
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 63 1e-09
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 63 1e-09
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 63 1e-09
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 63 1e-09
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 62 2e-09
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 62 2e-09
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 62 2e-09
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 62 2e-09
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 62 2e-09
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 62 2e-09
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 62 2e-09
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 62 2e-09
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 62 2e-09
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 60 5e-09
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 60 5e-09
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 60 5e-09
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 60 5e-09
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 60 5e-09
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 60 5e-09
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 60 5e-09
BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 60 5e-09
BC128535-1|AAI28536.1| 143|Homo sapiens CYP21A2 protein protein. 60 5e-09
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 60 5e-09
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 60 5e-09
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 5e-09
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 5e-09
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 60 5e-09
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 5e-09
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 5e-09
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 5e-09
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 5e-09
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 5e-09
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 60 5e-09
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 60 5e-09
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 60 5e-09
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 60 5e-09
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 60 5e-09
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 60 5e-09
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 60 5e-09
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 60 5e-09
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 60 5e-09
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 60 5e-09
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 60 7e-09
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 60 7e-09
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 60 7e-09
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 60 7e-09
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 60 7e-09
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 7e-09
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 60 7e-09
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 60 7e-09
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 60 7e-09
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 60 7e-09
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 60 7e-09
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 60 7e-09
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 60 9e-09
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 60 9e-09
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 59 1e-08
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 59 1e-08
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 59 2e-08
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 59 2e-08
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 59 2e-08
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 59 2e-08
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 58 3e-08
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 58 3e-08
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 58 3e-08
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 58 3e-08
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 58 4e-08
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 58 4e-08
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 58 4e-08
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 58 4e-08
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 58 4e-08
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 56 9e-08
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 56 1e-07
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 56 1e-07
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 56 1e-07
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 56 1e-07
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 56 1e-07
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 56 1e-07
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 56 1e-07
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 56 2e-07
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 55 2e-07
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 55 2e-07
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 55 2e-07
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 55 2e-07
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 55 2e-07
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 55 2e-07
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 55 2e-07
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 55 2e-07
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 55 2e-07
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 55 2e-07
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 55 3e-07
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 54 6e-07
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 54 6e-07
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 54 6e-07
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 54 6e-07
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 53 8e-07
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 52 1e-06
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 52 2e-06
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 52 2e-06
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 52 2e-06
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 52 2e-06
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 52 2e-06
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 52 2e-06
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 52 2e-06
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 52 2e-06
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 52 2e-06
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 52 2e-06
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 52 2e-06
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 52 2e-06
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 52 2e-06
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 52 2e-06
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 52 2e-06
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 52 2e-06
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 52 2e-06
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 52 2e-06
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 52 2e-06
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 52 2e-06
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 52 2e-06
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 52 2e-06
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 50 6e-06
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 50 6e-06
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 50 6e-06
EF122244-1|ABO41979.1| 216|Homo sapiens cytochrome P450 2F1 var... 50 8e-06
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 50 8e-06
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 49 1e-05
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 49 2e-05
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 49 2e-05
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 48 2e-05
AM233518-1|CAJ80721.1| 157|Homo sapiens cytochrome P450 1A1 pro... 48 2e-05
AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1 pro... 48 2e-05
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 48 3e-05
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 48 3e-05
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 48 3e-05
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 48 3e-05
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 48 3e-05
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 48 3e-05
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 48 3e-05
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 48 3e-05
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 48 3e-05
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 48 3e-05
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 48 3e-05
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 48 3e-05
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 48 4e-05
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 48 4e-05
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 48 4e-05
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 48 4e-05
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 48 4e-05
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 46 1e-04
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 46 1e-04
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 46 1e-04
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 46 1e-04
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 46 1e-04
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 46 1e-04
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 46 2e-04
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 45 2e-04
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 45 2e-04
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 45 2e-04
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 45 2e-04
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 45 2e-04
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 45 2e-04
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 45 2e-04
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 45 2e-04
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 45 2e-04
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 45 2e-04
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 45 2e-04
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 45 2e-04
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 45 2e-04
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 45 2e-04
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 45 2e-04
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 45 2e-04
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 45 2e-04
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 45 2e-04
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 45 2e-04
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 45 2e-04
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 45 2e-04
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 45 2e-04
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 45 3e-04
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 45 3e-04
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 44 4e-04
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 44 4e-04
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 44 4e-04
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 44 4e-04
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 44 4e-04
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 44 5e-04
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 44 5e-04
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 43 9e-04
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 43 9e-04
BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family... 42 0.002
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 42 0.002
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 42 0.003
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 42 0.003
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 41 0.004
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 41 0.004
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 41 0.004
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 41 0.004
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 41 0.004
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 41 0.004
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 41 0.004
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 41 0.004
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 41 0.004
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 41 0.005
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 40 0.006
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 40 0.006
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 40 0.006
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 40 0.006
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 40 0.008
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 40 0.008
X56088-1|CAA39568.1| 504|Homo sapiens cholesterol 7-alpha-hydr... 40 0.011
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 40 0.011
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 40 0.011
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 40 0.011
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 39 0.014
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 39 0.019
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 38 0.025
M93133-1|AAA58435.1| 504|Homo sapiens cholesterol 7-alpha hydro... 38 0.025
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 38 0.025
BC112184-1|AAI12185.1| 504|Homo sapiens cytochrome P450, family... 38 0.025
BC101777-1|AAI01778.1| 504|Homo sapiens cytochrome P450, family... 38 0.025
BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 38 0.033
BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 38 0.033
BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 38 0.033
AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 38 0.033
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 38 0.043
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 38 0.043
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 38 0.043
X58899-1|CAA41703.1| 368|Homo sapiens steroid 21-monooxygenase ... 38 0.043
X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase ... 38 0.043
AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 38 0.043
BC029155-1|AAH29155.1| 489|Homo sapiens CYP7B1 protein protein. 37 0.076
AF176805-1|AAK11850.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 37 0.076
AF127090-1|AAD20021.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 37 0.076
AF029403-1|AAC95426.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 37 0.076
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 36 0.13
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 36 0.13
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 36 0.13
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 36 0.13
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 36 0.13
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 36 0.13
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 36 0.13
D50111-1|BAA08796.1| 46|Homo sapiens CYP2EI protein. 36 0.17
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 35 0.23
BC067444-1|AAH67444.1| 501|Homo sapiens cytochrome P450, family... 35 0.30
BC067442-1|AAH67442.1| 501|Homo sapiens cytochrome P450, family... 35 0.30
BC067441-1|AAH67441.1| 501|Homo sapiens cytochrome P450, family... 35 0.30
BC067434-1|AAH67434.1| 501|Homo sapiens cytochrome P450, family... 35 0.30
AF090320-1|AAD19877.1| 501|Homo sapiens sterol 12-alpha-hydroxy... 35 0.30
AF090318-1|AAC63037.1| 462|Homo sapiens sterol 12-alpha hydroxy... 35 0.30
EF122243-1|ABO41978.1| 47|Homo sapiens cytochrome P450 2F1 var... 34 0.40
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 34 0.40
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 33 0.93
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 33 1.2
AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 33 1.2
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 33 1.2
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 32 1.6
D84124-1|BAA28219.1| 509|Homo sapiens prostacyclin synthase pro... 32 2.1
D83402-1|BAA11910.1| 500|Homo sapiens prostacyclin synthase pro... 32 2.1
D38145-1|BAA07343.1| 500|Homo sapiens prostacyclin synthase pro... 32 2.1
BC101811-1|AAI01812.1| 500|Homo sapiens prostaglandin I2 (prost... 32 2.1
BC101809-1|AAI01810.1| 500|Homo sapiens prostaglandin I2 (prost... 32 2.1
AL118525-1|CAC14162.1| 500|Homo sapiens prostaglandin I2 (prost... 32 2.1
AF297052-1|AAG31785.1| 500|Homo sapiens prostacyclin synthase p... 32 2.1
AF297051-1|AAG31784.1| 500|Homo sapiens prostacyclin synthase p... 32 2.1
AF297050-1|AAG31783.1| 500|Homo sapiens prostacyclin synthase p... 32 2.1
AF297049-1|AAG31782.1| 500|Homo sapiens prostacyclin synthase p... 32 2.1
AF297048-1|AAG31781.1| 500|Homo sapiens prostacyclin synthase p... 32 2.1
BC109310-1|AAI09311.1| 873|Homo sapiens N-deacetylase/N-sulfotr... 31 3.8
BC109309-1|AAI09310.1| 873|Homo sapiens N-deacetylase/N-sulfotr... 31 3.8
AF076605-1|AAD46061.1| 876|Homo sapiens heparan N-deacetylase/N... 31 3.8
AF074924-1|AAD15978.1| 873|Homo sapiens heparan sulfate N-deace... 31 3.8
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 31 5.0
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 31 5.0
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 31 5.0
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 30 8.7
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 30 8.7
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 30 8.7
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 30 8.7
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 30 8.7
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 101 bits (241), Expect = 3e-21
Identities = 39/85 (45%), Positives = 58/85 (68%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
+++VP+ IPH E+ L Y IPK +++P W++H DP +WE+PE F P RFL G
Sbjct: 414 TVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQ 473
Query: 429 LLKPQEFIPFQTGKRMCPGDELSRM 503
L+K + FIPF GKR+C G++L++M
Sbjct: 474 LIKKETFIPFGIGKRVCMGEQLAKM 498
Score = 52.4 bits (120), Expect = 1e-06
Identities = 27/75 (36%), Positives = 43/75 (57%), Gaps = 3/75 (4%)
Frame = +1
Query: 34 DEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXX 204
+E L +++ D+F AG DTT+ +L W LLYM+L P+ QE++ +EI +
Sbjct: 339 EEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKA 398
Query: 205 RLPLLMAAICETQRI 249
++P A I E QR+
Sbjct: 399 QMPYTEATIMEVQRL 413
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 101 bits (241), Expect = 3e-21
Identities = 39/85 (45%), Positives = 58/85 (68%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
+++VP+ IPH E+ L Y IPK +++P W++H DP +WE+PE F P RFL G
Sbjct: 414 TVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQ 473
Query: 429 LLKPQEFIPFQTGKRMCPGDELSRM 503
L+K + FIPF GKR+C G++L++M
Sbjct: 474 LIKKETFIPFGIGKRVCMGEQLAKM 498
Score = 52.4 bits (120), Expect = 1e-06
Identities = 27/75 (36%), Positives = 43/75 (57%), Gaps = 3/75 (4%)
Frame = +1
Query: 34 DEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXX 204
+E L +++ D+F AG DTT+ +L W LLYM+L P+ QE++ +EI +
Sbjct: 339 EEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKA 398
Query: 205 RLPLLMAAICETQRI 249
++P A I E QR+
Sbjct: 399 QMPYTEATIMEVQRL 413
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 81.4 bits (192), Expect = 3e-15
Identities = 36/83 (43%), Positives = 47/83 (56%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+GI H EDA + Y IPK VI +++H D W +PE F P RFL G
Sbjct: 374 IVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFA 433
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + +PF G+R C G+ L+RM
Sbjct: 434 KKEALVPFSLGRRHCLGEHLARM 456
Score = 44.8 bits (101), Expect = 3e-04
Identities = 20/52 (38%), Positives = 35/52 (67%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
DP++ + + E L F + ++ AG +TT+ L W +L+MAL+P Q +++KEI
Sbjct: 290 DPSSTFSK-ENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEI 340
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 81.4 bits (192), Expect = 3e-15
Identities = 36/83 (43%), Positives = 47/83 (56%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+GI H EDA + Y IPK VI +++H D W +PE F P RFL G
Sbjct: 374 IVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFA 433
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + +PF G+R C G+ L+RM
Sbjct: 434 KKEALVPFSLGRRHCLGEHLARM 456
Score = 44.8 bits (101), Expect = 3e-04
Identities = 20/52 (38%), Positives = 35/52 (67%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
DP++ + + E L F + ++ AG +TT+ L W +L+MAL+P Q +++KEI
Sbjct: 290 DPSSTFSK-ENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEI 340
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 81.4 bits (192), Expect = 3e-15
Identities = 36/83 (43%), Positives = 47/83 (56%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+GI H EDA + Y IPK VI +++H D W +PE F P RFL G
Sbjct: 374 IVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFA 433
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + +PF G+R C G+ L+RM
Sbjct: 434 KKEALVPFSLGRRHCLGEHLARM 456
Score = 44.8 bits (101), Expect = 3e-04
Identities = 20/52 (38%), Positives = 35/52 (67%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
DP++ + + E L F + ++ AG +TT+ L W +L+MAL+P Q +++KEI
Sbjct: 290 DPSSTFSK-ENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEI 340
>AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ45208 fis, clone BRCAN2015402, highly similar
to Cytochrome P450 2G1 (EC 1.14.14.1). ).
Length = 146
Score = 80.2 bits (189), Expect = 6e-15
Identities = 33/83 (39%), Positives = 50/83 (60%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+PH I+D Y +PK V PL ++ DP + P+ F P+ FL + G
Sbjct: 17 IVPMGVPHNIIQDTQFRGYLLPKGTDVFPLLGSVLKDPKYFRYPDAFYPQHFLDEQGRFK 76
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F+PF +GKR+C G+ ++RM
Sbjct: 77 KNEAFVPFSSGKRICLGEAMARM 99
>BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 75.8 bits (178), Expect = 1e-13
Identities = 37/87 (42%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VPV IPH + + Y IPK+ +V QW+++ DP W PE F P RFL +DG
Sbjct: 392 SSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPLKWPNPENFDPARFLDKDGL 451
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSRM 503
+ K + F GKR C G+ELS+M
Sbjct: 452 ISKDLTSRVMIFSVGKRRCIGEELSKM 478
Score = 37.9 bits (84), Expect = 0.033
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E + + D+FGA DT S L W LL +P+ Q ++ E ++
Sbjct: 318 ENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPN 377
Query: 208 LPLLMAAICETQRIRS 255
LP ++A + E R S
Sbjct: 378 LPYVLAFLYEAMRFSS 393
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 75.8 bits (178), Expect = 1e-13
Identities = 33/82 (40%), Positives = 49/82 (59%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+GIP + Y +P+ V PL +I DPN+++ PE+F P RFL DG
Sbjct: 366 LVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFR 425
Query: 435 KPQEFIPFQTGKRMCPGDELSR 500
K + F+PF GKR+C G+ L++
Sbjct: 426 KHEAFLPFSLGKRVCLGEGLAK 447
Score = 33.5 bits (73), Expect = 0.70
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 3/101 (2%)
Frame = +1
Query: 1 ESGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LX 171
E +P + L ++ +F AG T S T+ + LL + +P Q+ +R+E+ L
Sbjct: 279 EEQNPGTEFTNKNMLMTVIYLLF-AGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG 337
Query: 172 XXXXXXXXXXXRLPLLMAAICETQRIRSLFQWEYPMVV*RT 294
RLP A + E QR+ +L P + RT
Sbjct: 338 AGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRT 378
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 75.8 bits (178), Expect = 1e-13
Identities = 33/82 (40%), Positives = 49/82 (59%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+GIP + Y +P+ V PL +I DPN+++ PE+F P RFL DG
Sbjct: 366 LVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFR 425
Query: 435 KPQEFIPFQTGKRMCPGDELSR 500
K + F+PF GKR+C G+ L++
Sbjct: 426 KHEAFLPFSLGKRVCLGEGLAK 447
Score = 33.5 bits (73), Expect = 0.70
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 3/101 (2%)
Frame = +1
Query: 1 ESGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LX 171
E +P + L ++ +F AG T S T+ + LL + +P Q+ +R+E+ L
Sbjct: 279 EEQNPGTEFTNKNMLMTVIYLLF-AGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG 337
Query: 172 XXXXXXXXXXXRLPLLMAAICETQRIRSLFQWEYPMVV*RT 294
RLP A + E QR+ +L P + RT
Sbjct: 338 AGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRT 378
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 75.8 bits (178), Expect = 1e-13
Identities = 33/82 (40%), Positives = 49/82 (59%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+GIP + Y +P+ V PL +I DPN+++ PE+F P RFL DG
Sbjct: 366 LVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFR 425
Query: 435 KPQEFIPFQTGKRMCPGDELSR 500
K + F+PF GKR+C G+ L++
Sbjct: 426 KHEAFLPFSLGKRVCLGEGLAK 447
Score = 33.5 bits (73), Expect = 0.70
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 3/101 (2%)
Frame = +1
Query: 1 ESGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LX 171
E +P + L ++ +F AG T S T+ + LL + +P Q+ +R+E+ L
Sbjct: 279 EEQNPGTEFTNKNMLMTVIYLLF-AGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG 337
Query: 172 XXXXXXXXXXXRLPLLMAAICETQRIRSLFQWEYPMVV*RT 294
RLP A + E QR+ +L P + RT
Sbjct: 338 AGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRT 378
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 75.8 bits (178), Expect = 1e-13
Identities = 33/82 (40%), Positives = 49/82 (59%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+GIP + Y +P+ V PL +I DPN+++ PE+F P RFL DG
Sbjct: 366 LVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFR 425
Query: 435 KPQEFIPFQTGKRMCPGDELSR 500
K + F+PF GKR+C G+ L++
Sbjct: 426 KHEAFLPFSLGKRVCLGEGLAK 447
Score = 33.5 bits (73), Expect = 0.70
Identities = 27/101 (26%), Positives = 44/101 (43%), Gaps = 3/101 (2%)
Frame = +1
Query: 1 ESGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LX 171
E +P + L ++ +F AG T S T+ + LL + +P Q+ +R+E+ L
Sbjct: 279 EEQNPGTEFTNKNMLMTVIYLLF-AGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG 337
Query: 172 XXXXXXXXXXXRLPLLMAAICETQRIRSLFQWEYPMVV*RT 294
RLP A + E QR+ +L P + RT
Sbjct: 338 AGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRT 378
>U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochrome
P450 protein.
Length = 543
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/87 (42%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VPV IPH + + Y IPK+ +V QW+++ DP W PE F P RFL +DG
Sbjct: 392 SSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPLKWPNPENFDPARFLDKDGL 451
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSRM 503
+ K + F GKR C G+ELS+M
Sbjct: 452 INKDLTSRVMIFSVGKRRCIGEELSKM 478
Score = 37.9 bits (84), Expect = 0.033
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E + + D+FGA DT S L W LL +P+ Q ++ E ++
Sbjct: 318 ENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPN 377
Query: 208 LPLLMAAICETQRIRS 255
LP ++A + E R S
Sbjct: 378 LPYVLAFLYEAMRFSS 393
>U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein.
Length = 543
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/87 (42%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VPV IPH + + Y IPK+ +V QW+++ DP W PE F P RFL +DG
Sbjct: 392 SSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPVKWPNPENFDPARFLDKDGL 451
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSRM 503
+ K + F GKR C G+ELS+M
Sbjct: 452 INKDLTSRVMIFSVGKRRCIGEELSKM 478
Score = 37.9 bits (84), Expect = 0.033
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E + + D+FGA DT S L W LL +P+ Q ++ E ++
Sbjct: 318 ENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPN 377
Query: 208 LPLLMAAICETQRIRS 255
LP ++A + E R S
Sbjct: 378 LPYVLAFLYEAMRFSS 393
>BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/87 (42%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VPV IPH + + Y IPK+ +V QW+++ DP W PE F P RFL +DG
Sbjct: 392 SSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPVKWPNPENFDPARFLDKDGL 451
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSRM 503
+ K + F GKR C G+ELS+M
Sbjct: 452 INKDLTSRVMIFSVGKRRCIGEELSKM 478
Score = 37.9 bits (84), Expect = 0.033
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E + + D+FGA DT S L W LL +P+ Q ++ E ++
Sbjct: 318 ENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPN 377
Query: 208 LPLLMAAICETQRIRS 255
LP ++A + E R S
Sbjct: 378 LPYVLAFLYEAMRFSS 393
>BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/87 (42%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VPV IPH + + Y IPK+ +V QW+++ DP W PE F P RFL +DG
Sbjct: 392 SSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPVKWPNPENFDPARFLDKDGL 451
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSRM 503
+ K + F GKR C G+ELS+M
Sbjct: 452 INKDLTSRVMIFSVGKRRCIGEELSKM 478
Score = 37.9 bits (84), Expect = 0.033
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E + + D+FGA DT S L W LL +P+ Q ++ E ++
Sbjct: 318 ENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPN 377
Query: 208 LPLLMAAICETQRIRS 255
LP ++A + E R S
Sbjct: 378 LPYVLAFLYEAMRFSS 393
>AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family 1,
subfamily B, polypeptide 1 protein.
Length = 543
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/87 (42%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VPV IPH + + Y IPK+ +V QW+++ DP W PE F P RFL +DG
Sbjct: 392 SSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPLKWPNPENFDPARFLDKDGL 451
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSRM 503
+ K + F GKR C G+ELS+M
Sbjct: 452 INKDLTSRVMIFSVGKRRCIGEELSKM 478
Score = 37.9 bits (84), Expect = 0.033
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E + + D+FGA DT S L W LL +P+ Q ++ E ++
Sbjct: 318 ENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPN 377
Query: 208 LPLLMAAICETQRIRS 255
LP ++A + E R S
Sbjct: 378 LPYVLAFLYEAMRFSS 393
>AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1
protein.
Length = 543
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/87 (42%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VPV IPH + + Y IPK+ +V QW+++ DP W PE F P RFL +DG
Sbjct: 392 SSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPLKWPNPENFDPARFLDKDGL 451
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSRM 503
+ K + F GKR C G+ELS+M
Sbjct: 452 INKDLTSRVMIFSVGKRRCIGEELSKM 478
Score = 37.9 bits (84), Expect = 0.033
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E + + D+FGA DT S L W LL +P+ Q ++ E ++
Sbjct: 318 ENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPN 377
Query: 208 LPLLMAAICETQRIRS 255
LP ++A + E R S
Sbjct: 378 LPYVLAFLYEAMRFSS 393
>AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein.
Length = 543
Score = 75.4 bits (177), Expect = 2e-13
Identities = 37/87 (42%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VPV IPH + + Y IPK+ +V QW+++ DP W PE F P RFL +DG
Sbjct: 392 SSFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPVKWPNPENFDPARFLDKDGL 451
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSRM 503
+ K + F GKR C G+ELS+M
Sbjct: 452 INKDLTSRVMIFSVGKRRCIGEELSKM 478
Score = 37.9 bits (84), Expect = 0.033
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E + + D+FGA DT S L W LL +P+ Q ++ E ++
Sbjct: 318 ENVPATITDIFGASQDTLSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPN 377
Query: 208 LPLLMAAICETQRIRS 255
LP ++A + E R S
Sbjct: 378 LPYVLAFLYEAMRFSS 393
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 372 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 431
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 432 KPEAFLPFSAGRRACLGEPLARM 454
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 287 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 345
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 346 RRPEMGDQAHMPYTTAVIHEVQR 368
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 245 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 304
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 305 KPEAFLPFSAGRRACLGEPLARM 327
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 160 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 218
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 219 RRPEMGDQAHMPYTTAVIHEVQR 241
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 372 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 431
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 432 KPEAFLPFSAGRRACLGEPLARM 454
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 287 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 345
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 346 RRPEMGDQAHMPYTTAVIHEVQR 368
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDMIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 368 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 427
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 428 KPEAFLPFSAGRRACLGEPLARM 450
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 283 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 341
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 342 RRPEMGDQAHMPYTTAVIHEVQR 364
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 318 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 377
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 378 KPEAFLPFSAGRRACLGEPLARM 400
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 233 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 291
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 292 RRPEMGDQAHMPYTTAVIHEVQR 314
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDEVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 318 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 377
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 378 KPEAFLPFSAGRRACLGEPLARM 400
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 233 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 291
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 292 RRPEMGDQAHMPYTTAVIHEVQR 314
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 318 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 377
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 378 KPEAFLPFSAGRRACLGEPLARM 400
Score = 52.8 bits (121), Expect = 1e-06
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 233 GNPESSF-NDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 291
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 292 RRPEMGDQAHMPYTTAVIHEVQR 314
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 388 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 447
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 448 KPEAFLPFSAGRRACLGEPLARM 470
Score = 35.9 bits (79), Expect = 0.13
Identities = 19/46 (41%), Positives = 27/46 (58%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQ 144
G P + + DE L ++ ++F AG+ TT TLAW LL M L + Q
Sbjct: 284 GSPESSF-NDENLRIVVGNLFLAGMVTTLTTLAWGLLLMILHLDVQ 328
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 74.9 bits (176), Expect = 2e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 438 IVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 497
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 498 KPEAFLPFSAGRRACLGEPLARM 520
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 353 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 411
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 412 RRPEMGDQAHMPYTTAVIHEVQR 434
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 74.1 bits (174), Expect = 4e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 74.1 bits (174), Expect = 4e-13
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
IVP+G+ H D + +RIPK +I ++ D VWE+P +F P FL G +
Sbjct: 369 IVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFV 428
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
KP+ F+PF G+R C G+ L+RM
Sbjct: 429 KPEAFLPFSAGRRACLGEPLARM 451
Score = 54.0 bits (124), Expect = 5e-07
Identities = 31/83 (37%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 7 GDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXX 177
G+P + + DE L ++AD+F AG+ TTS TLAW LL M L P+ Q +++EI +
Sbjct: 284 GNPESSF-NDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQV 342
Query: 178 XXXXXXXXXRLPLLMAAICETQR 246
+P A I E QR
Sbjct: 343 RRPEMGDQAHMPYTTAVIHEVQR 365
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 73.7 bits (173), Expect = 5e-13
Identities = 33/83 (39%), Positives = 46/83 (55%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP +PH D Y IPK +V+P ++ D + +PEKFKP FL ++G
Sbjct: 363 LVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFK 422
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
F PF TGKR+C G+ L+RM
Sbjct: 423 YSDYFKPFSTGKRVCAGEGLARM 445
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXRLPLLMA 225
+AD+F AG +TTS TL + LL + +PE +E++ +EI + +P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 226 AICETQRIRSLFQWEYP 276
+ E QR +L P
Sbjct: 353 VVHEIQRFITLVPSNLP 369
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 73.7 bits (173), Expect = 5e-13
Identities = 33/83 (39%), Positives = 46/83 (55%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP +PH D Y IPK +V+P ++ D + +PEKFKP FL ++G
Sbjct: 363 LVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFK 422
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
F PF TGKR+C G+ L+RM
Sbjct: 423 YSDYFKPFSTGKRVCAGEGLARM 445
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXRLPLLMA 225
+AD+F AG +TTS TL + LL + +PE +E++ +EI + +P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 226 AICETQRIRSLFQWEYP 276
+ E QR +L P
Sbjct: 353 VVHEIQRFITLVPSNLP 369
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 73.7 bits (173), Expect = 5e-13
Identities = 33/83 (39%), Positives = 46/83 (55%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP +PH D Y IPK +V+P ++ D + +PEKFKP FL ++G
Sbjct: 363 LVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFK 422
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
F PF TGKR+C G+ L+RM
Sbjct: 423 YSDYFKPFSTGKRVCAGEGLARM 445
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXRLPLLMA 225
+AD+F AG +TTS TL + LL + +PE +E++ +EI + +P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 226 AICETQRIRSLFQWEYP 276
+ E QR +L P
Sbjct: 353 VVHEIQRFITLVPSNLP 369
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 73.7 bits (173), Expect = 5e-13
Identities = 33/83 (39%), Positives = 46/83 (55%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP +PH D Y IPK +V+P ++ D + +PEKFKP FL ++G
Sbjct: 363 LVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFK 422
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
F PF TGKR+C G+ L+RM
Sbjct: 423 YSDYFKPFSTGKRVCAGEGLARM 445
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXRLPLLMA 225
+AD+F AG +TTS TL + LL + +PE +E++ +EI + +P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 226 AICETQRIRSLFQWEYP 276
+ E QR +L P
Sbjct: 353 VVHEIQRFITLVPSNLP 369
>DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 73.7 bits (173), Expect = 5e-13
Identities = 33/83 (39%), Positives = 46/83 (55%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP +PH D Y IPK +V+P ++ D + +PEKFKP FL ++G
Sbjct: 363 LVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFK 422
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
F PF TGKR+C G+ L+RM
Sbjct: 423 YSDYFKPFSTGKRVCAGEGLARM 445
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXRLPLLMA 225
+AD+F AG +TTS TL + LL + +PE +E++ +EI + +P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 226 AICETQRIRSLFQWEYP 276
+ E QR +L P
Sbjct: 353 VVREIQRFITLVPSNLP 369
>BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 73.7 bits (173), Expect = 5e-13
Identities = 33/83 (39%), Positives = 46/83 (55%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP +PH D Y IPK +V+P ++ D + +PEKFKP FL ++G
Sbjct: 363 LVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFK 422
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
F PF TGKR+C G+ L+RM
Sbjct: 423 YSDYFKPFSTGKRVCAGEGLARM 445
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXRLPLLMA 225
+AD+F AG +TTS TL + LL + +PE +E++ +EI + +P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 226 AICETQRIRSLFQWEYP 276
+ E QR +L P
Sbjct: 353 VVHEIQRFITLVPSNLP 369
>AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 73.7 bits (173), Expect = 5e-13
Identities = 33/83 (39%), Positives = 46/83 (55%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP +PH D Y IPK +V+P ++ D + +PEKFKP FL ++G
Sbjct: 363 LVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFK 422
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
F PF TGKR+C G+ L+RM
Sbjct: 423 YSDYFKPFSTGKRVCAGEGLARM 445
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXRLPLLMA 225
+AD+F AG +TTS TL + LL + +PE +E++ +EI + +P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 226 AICETQRIRSLFQWEYP 276
+ E QR +L P
Sbjct: 353 VVHEIQRFITLVPSNLP 369
>AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2
protein.
Length = 516
Score = 73.7 bits (173), Expect = 5e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 49.2 bits (112), Expect = 1e-05
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDVFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 365 LPYLEAFILETFRHSSFLPFTIP 387
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 73.7 bits (173), Expect = 5e-13
Identities = 33/83 (39%), Positives = 46/83 (55%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP +PH D Y IPK +V+P ++ D + +PEKFKP FL ++G
Sbjct: 332 LVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFK 391
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
F PF TGKR+C G+ L+RM
Sbjct: 392 YSDYFKPFSTGKRVCAGEGLARM 414
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXRLPLLMA 225
+AD+F AG +TTS TL + LL + +PE +E++ +EI + +P + A
Sbjct: 262 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 321
Query: 226 AICETQRIRSLFQWEYP 276
+ E QR +L P
Sbjct: 322 VVHEIQRFITLVPSNLP 338
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 73.3 bits (172), Expect = 7e-13
Identities = 31/82 (37%), Positives = 46/82 (56%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
I+P+ +P D L Y +PK M++ A+H DP W P+ F P FL ++G
Sbjct: 375 IIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFK 433
Query: 435 KPQEFIPFQTGKRMCPGDELSR 500
K + F+PF GKR C G++L+R
Sbjct: 434 KREAFMPFSIGKRACLGEQLAR 455
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Frame = +1
Query: 4 SGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXX 174
+G+PT+ + +E L D+F AG +TTS TL W LLYMAL+PE QE+++ EI +
Sbjct: 289 TGNPTSSF-HEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQ 347
Query: 175 XXXXXXXXXXRLPLLMAAICETQRIRSLFQWEYPMVV 285
+P A I E QR+ ++ P V
Sbjct: 348 GQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREV 384
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 73.3 bits (172), Expect = 7e-13
Identities = 34/87 (39%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 379 SPFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 438
Query: 429 LL-KP--QEFIPFQTGKRMCPGDELSR 500
+ KP ++ + F GKR C G+ L++
Sbjct: 439 AINKPLSEKMMLFGMGKRRCIGEVLAK 465
Score = 47.2 bits (107), Expect = 5e-05
Identities = 26/73 (35%), Positives = 40/73 (54%), Gaps = 3/73 (4%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ L+ D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 305 EKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 364
Query: 208 LPLLMAAICETQR 246
LP L A I ET R
Sbjct: 365 LPYLEAFILETFR 377
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 73.3 bits (172), Expect = 7e-13
Identities = 31/82 (37%), Positives = 46/82 (56%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
I+P+ +P D L Y +PK M++ A+H DP W P+ F P FL ++G
Sbjct: 375 IIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFK 433
Query: 435 KPQEFIPFQTGKRMCPGDELSR 500
K + F+PF GKR C G++L+R
Sbjct: 434 KREAFMPFSIGKRACLGEQLAR 455
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Frame = +1
Query: 4 SGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXX 174
+G+PT+ + +E L D+F AG +TTS TL W LLYMAL+PE QE+++ EI +
Sbjct: 289 TGNPTSSF-HEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQ 347
Query: 175 XXXXXXXXXXRLPLLMAAICETQRIRSLFQWEYPMVV 285
+P A I E QR+ ++ P V
Sbjct: 348 GQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREV 384
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 73.3 bits (172), Expect = 7e-13
Identities = 31/82 (37%), Positives = 46/82 (56%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
I+P+ +P D L Y +PK M++ A+H DP W P+ F P FL ++G
Sbjct: 375 IIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFK 433
Query: 435 KPQEFIPFQTGKRMCPGDELSR 500
K + F+PF GKR C G++L+R
Sbjct: 434 KREAFMPFSIGKRACLGEQLAR 455
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Frame = +1
Query: 4 SGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXX 174
+G+PT+ + +E L D+F AG +TTS TL W LLYMAL+PE QE+++ EI +
Sbjct: 289 TGNPTSSF-HEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQ 347
Query: 175 XXXXXXXXXXRLPLLMAAICETQRIRSLFQWEYPMVV 285
+P A I E QR+ ++ P V
Sbjct: 348 GQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREV 384
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 73.3 bits (172), Expect = 7e-13
Identities = 31/82 (37%), Positives = 46/82 (56%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
I+P+ +P D L Y +PK M++ A+H DP W P+ F P FL ++G
Sbjct: 375 IIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFK 433
Query: 435 KPQEFIPFQTGKRMCPGDELSR 500
K + F+PF GKR C G++L+R
Sbjct: 434 KREAFMPFSIGKRACLGEQLAR 455
Score = 58.0 bits (134), Expect = 3e-08
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Frame = +1
Query: 4 SGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXX 174
+G+PT+ + +E L D+F AG +TTS TL W LLYMAL+PE QE+++ EI +
Sbjct: 289 TGNPTSSF-HEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQ 347
Query: 175 XXXXXXXXXXRLPLLMAAICETQRIRSLFQWEYPMVV 285
+P A I E QR+ ++ P V
Sbjct: 348 GQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREV 384
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 73.3 bits (172), Expect = 7e-13
Identities = 31/82 (37%), Positives = 46/82 (56%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
I+P+ +P D L Y +PK M++ A+H DP W P+ F P FL ++G
Sbjct: 375 IIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL-ENGQFK 433
Query: 435 KPQEFIPFQTGKRMCPGDELSR 500
K + F+PF GKR C G++L+R
Sbjct: 434 KREAFMPFSIGKRACLGEQLAR 455
Score = 57.6 bits (133), Expect = 4e-08
Identities = 35/97 (36%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Frame = +1
Query: 4 SGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXX 174
+G+PT+ + +E L D+F AG +TTS TL W LLYMAL+PE QE+++ EI +
Sbjct: 289 TGNPTSSF-HEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQVEIDRVIGQ 347
Query: 175 XXXXXXXXXXRLPLLMAAICETQRIRSLFQWEYPMVV 285
+P A I E QR+ ++ P V
Sbjct: 348 GQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREV 384
>DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1
protein.
Length = 195
Score = 72.1 bits (169), Expect = 2e-12
Identities = 36/87 (41%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VPV I H + + Y IPK+ +V QW+++ DP W PE F P RFL +DG
Sbjct: 44 SSFVPVTISHATTANTSVLGYHIPKDTVVFVNQWSVNHDPLKWPNPENFDPARFLDKDGL 103
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSRM 503
+ K + F GKR C G+ELS+M
Sbjct: 104 INKDLTSRVMIFSVGKRRCIGEELSKM 130
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 71.7 bits (168), Expect = 2e-12
Identities = 32/82 (39%), Positives = 45/82 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP +PH D Y IPK +V+P ++ D + +PEKFKP FL ++G
Sbjct: 363 LVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFK 422
Query: 435 KPQEFIPFQTGKRMCPGDELSR 500
F PF TGKR+C G+ L+R
Sbjct: 423 YSDYFKPFSTGKRVCAGEGLAR 444
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXRLPLLMA 225
+AD+F AG +TTS TL + LL + +PE +E++ +EI + +P + A
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 352
Query: 226 AICETQRIRSLFQWEYP 276
+ E QR +L P
Sbjct: 353 VVHEIQRFITLVPSNLP 369
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 70.5 bits (165), Expect = 5e-12
Identities = 32/85 (37%), Positives = 46/85 (54%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +VP G+PH D NY IPK ++ L ++ D + P F P FL ++G+
Sbjct: 359 SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN 418
Query: 429 LLKPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 419 FKKSDYFMPFSAGKRICAGEGLARM 443
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L +AD+F AG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYSDLVPTGVPHAV 370
>X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120
AA) protein.
Length = 210
Score = 70.5 bits (165), Expect = 5e-12
Identities = 32/85 (37%), Positives = 46/85 (54%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +VP G+PH D NY IPK ++ L ++ D + P F P FL ++G+
Sbjct: 79 SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDREFPNPNIFDPGHFLDKNGN 138
Query: 429 LLKPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 139 FKKSDYFMPFSAGKRICAGEGLARM 163
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L +AD+F AG +TTS TL + LL + PE ++++EI +
Sbjct: 5 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 64
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 65 MPYTDAVVHEIQRYSDLVPTGVPHAV 90
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 70.5 bits (165), Expect = 5e-12
Identities = 32/85 (37%), Positives = 46/85 (54%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +VP G+PH D NY IPK ++ L ++ D + P F P FL ++G+
Sbjct: 331 SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN 390
Query: 429 LLKPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 391 FKKSDYFMPFSAGKRICAGEGLARM 415
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L +AD+F AG +TTS TL + LL + PE ++++EI +
Sbjct: 257 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 316
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 317 MPYTDAVVHEIQRYSDLVPTGVPHAV 342
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 70.5 bits (165), Expect = 5e-12
Identities = 32/85 (37%), Positives = 46/85 (54%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +VP G+PH D NY IPK ++ L ++ D + P F P FL ++G+
Sbjct: 359 SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN 418
Query: 429 LLKPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 419 FKKSDYFMPFSAGKRICAGEGLARM 443
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L +AD+F AG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYSDLVPTGVPHAV 370
>EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1
variant protein.
Length = 491
Score = 70.5 bits (165), Expect = 5e-12
Identities = 31/83 (37%), Positives = 46/83 (55%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
I+P+ +PH D + IPK VI L +H DP+ + P++F P FL + S
Sbjct: 362 IIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSFK 421
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF G+R+C G+ L+RM
Sbjct: 422 KSPAFMPFSAGRRLCLGESLARM 444
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 70.5 bits (165), Expect = 5e-12
Identities = 32/85 (37%), Positives = 46/85 (54%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +VP G+PH D NY IPK ++ L ++ D + P F P FL ++G+
Sbjct: 359 SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN 418
Query: 429 LLKPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 419 FKKSDYFMPFSAGKRICAGEGLARM 443
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L +AD+F AG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYSDLVPTGVPHAV 370
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 70.5 bits (165), Expect = 5e-12
Identities = 32/85 (37%), Positives = 46/85 (54%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +VP G+PH D NY IPK ++ L ++ D + P F P FL ++G+
Sbjct: 359 SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN 418
Query: 429 LLKPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 419 FKKSDYFMPFSAGKRICAGEGLARM 443
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L +AD+F AG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYSDLVPTGVPHAV 370
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 70.5 bits (165), Expect = 5e-12
Identities = 32/85 (37%), Positives = 46/85 (54%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +VP G+PH D NY IPK ++ L ++ D + P F P FL ++G+
Sbjct: 359 SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGN 418
Query: 429 LLKPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 419 FKKSDYFMPFSAGKRICAGEGLARM 443
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L +AD+F AG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYSDLVPTGVPHAV 370
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 70.5 bits (165), Expect = 5e-12
Identities = 31/83 (37%), Positives = 46/83 (55%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
I+P+ +PH D + IPK VI L +H DP+ + P++F P FL + S
Sbjct: 366 IIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSFK 425
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF G+R+C G+ L+RM
Sbjct: 426 KSPAFMPFSAGRRLCLGESLARM 448
>M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein.
Length = 491
Score = 69.7 bits (163), Expect = 9e-12
Identities = 34/85 (40%), Positives = 53/85 (62%), Gaps = 1/85 (1%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMV-IPLQWAIHMDPNVWEEPEKFKPRRFLAQDG 425
S ++P+G+PH + Y IPK+ V + L A+H DP+ +E+P+ F P FL +G
Sbjct: 360 SDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALH-DPHYFEKPDAFNPDHFLDANG 418
Query: 426 SLLKPQEFIPFQTGKRMCPGDELSR 500
+L K + FIPF GKR+C G+ ++R
Sbjct: 419 ALKKTEAFIPFSLGKRICLGEGIAR 443
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 69.7 bits (163), Expect = 9e-12
Identities = 32/85 (37%), Positives = 46/85 (54%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +VP G+PH D NY IPK ++ L ++ D + P F P FL ++G+
Sbjct: 349 SDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGLFLDKNGN 408
Query: 429 LLKPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 409 FKKSDYFMPFSAGKRICAGEGLARM 433
Score = 35.9 bits (79), Expect = 0.13
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L +AD+F AG +TTS TL + LL + PE ++++EI +
Sbjct: 275 ENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSH 334
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 335 MPYTDAVVHEIQRYSDLVPTGVPHAV 360
>DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 69.7 bits (163), Expect = 9e-12
Identities = 34/85 (40%), Positives = 53/85 (62%), Gaps = 1/85 (1%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMV-IPLQWAIHMDPNVWEEPEKFKPRRFLAQDG 425
S ++P+G+PH + Y IPK+ V + L A+H DP+ +E+P+ F P FL +G
Sbjct: 360 SDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALH-DPHYFEKPDAFNPDHFLDANG 418
Query: 426 SLLKPQEFIPFQTGKRMCPGDELSR 500
+L K + FIPF GKR+C G+ ++R
Sbjct: 419 ALKKTEAFIPFSLGKRICLGEGIAR 443
>BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 69.7 bits (163), Expect = 9e-12
Identities = 34/85 (40%), Positives = 53/85 (62%), Gaps = 1/85 (1%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMV-IPLQWAIHMDPNVWEEPEKFKPRRFLAQDG 425
S ++P+G+PH + Y IPK+ V + L A+H DP+ +E+P+ F P FL +G
Sbjct: 360 SDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALH-DPHYFEKPDAFNPDHFLDANG 418
Query: 426 SLLKPQEFIPFQTGKRMCPGDELSR 500
+L K + FIPF GKR+C G+ ++R
Sbjct: 419 ALKKTEAFIPFSLGKRICLGEGIAR 443
>BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family 2,
subfamily B, polypeptide 6 protein.
Length = 491
Score = 69.7 bits (163), Expect = 9e-12
Identities = 34/85 (40%), Positives = 53/85 (62%), Gaps = 1/85 (1%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMV-IPLQWAIHMDPNVWEEPEKFKPRRFLAQDG 425
S ++P+G+PH + Y IPK+ V + L A+H DP+ +E+P+ F P FL +G
Sbjct: 360 SDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALH-DPHYFEKPDAFNPDHFLDANG 418
Query: 426 SLLKPQEFIPFQTGKRMCPGDELSR 500
+L K + FIPF GKR+C G+ ++R
Sbjct: 419 ALKKTEAFIPFSLGKRICLGEGIAR 443
>AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P450
2E1 protein.
Length = 97
Score = 69.7 bits (163), Expect = 9e-12
Identities = 31/81 (38%), Positives = 44/81 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP +PH D Y IPK +V+P ++ D + +PEKFKP FL ++G
Sbjct: 17 LVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFK 76
Query: 435 KPQEFIPFQTGKRMCPGDELS 497
F PF TGKR+C G+ L+
Sbjct: 77 YSDYFKPFSTGKRVCAGEGLA 97
>AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6
protein.
Length = 491
Score = 69.7 bits (163), Expect = 9e-12
Identities = 34/85 (40%), Positives = 53/85 (62%), Gaps = 1/85 (1%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMV-IPLQWAIHMDPNVWEEPEKFKPRRFLAQDG 425
S ++P+G+PH + Y IPK+ V + L A+H DP+ +E+P+ F P FL +G
Sbjct: 360 SDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALH-DPHYFEKPDAFNPDHFLDANG 418
Query: 426 SLLKPQEFIPFQTGKRMCPGDELSR 500
+L K + FIPF GKR+C G+ ++R
Sbjct: 419 ALKKTEAFIPFSLGKRICLGEGIAR 443
>AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein.
Length = 491
Score = 69.7 bits (163), Expect = 9e-12
Identities = 34/85 (40%), Positives = 53/85 (62%), Gaps = 1/85 (1%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMV-IPLQWAIHMDPNVWEEPEKFKPRRFLAQDG 425
S ++P+G+PH + Y IPK+ V + L A+H DP+ +E+P+ F P FL +G
Sbjct: 360 SDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALH-DPHYFEKPDAFNPDHFLDANG 418
Query: 426 SLLKPQEFIPFQTGKRMCPGDELSR 500
+L K + FIPF GKR+C G+ ++R
Sbjct: 419 ALKKTEAFIPFSLGKRICLGEGIAR 443
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 69.3 bits (162), Expect = 1e-11
Identities = 31/83 (37%), Positives = 46/83 (55%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
I+P+ +PH D + IPK VI L +H DP+ + P++F P FL + S
Sbjct: 362 IIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSFK 421
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF G+R+C G+ L+RM
Sbjct: 422 KSPAFMPFSAGRRLCLGELLARM 444
>M12078-1|AAA52154.1| 192|Homo sapiens POR protein.
Length = 192
Score = 68.5 bits (160), Expect = 2e-11
Identities = 33/88 (37%), Positives = 48/88 (54%), Gaps = 4/88 (4%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +P IPH D L + IPK V QW ++ DP +WE+P +F+P RFL DG+
Sbjct: 85 SSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGT 144
Query: 429 LL-KP---QEFIPFQTGKRMCPGDELSR 500
+ KP + + GKR C G+ L++
Sbjct: 145 AINKPLSEKMMMLVGMGKRRCIGEVLAK 172
Score = 50.4 bits (115), Expect = 6e-06
Identities = 29/83 (34%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXXXXR 207
E++ LL D+FGAG DT + ++W L+Y+ PE Q +I+KE ++ +
Sbjct: 11 EKIVNLLNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQ 70
Query: 208 LPLLMAAICETQRIRSLFQWEYP 276
LP L A I ET R S + P
Sbjct: 71 LPYLEAFILETFRHSSFLPFTIP 93
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 68.5 bits (160), Expect = 2e-11
Identities = 28/77 (36%), Positives = 44/77 (57%)
Frame = +3
Query: 270 IPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEF 449
+P D LG + +PK VIPL ++ +D W+ P +F P FL +G +K + F
Sbjct: 364 VPRCTAADTQLGGFLLPKGTPVIPLLTSVLLDETQWQTPGQFNPGHFLDANGHFVKREAF 423
Query: 450 IPFQTGKRMCPGDELSR 500
+PF G+R+C G+ L+R
Sbjct: 424 LPFSAGRRVCVGERLAR 440
Score = 38.3 bits (85), Expect = 0.025
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 3/89 (3%)
Frame = +1
Query: 1 ESGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILX 171
+ DP L+ + L DM AG +TTS TL W L M P+ Q +++E +L
Sbjct: 273 QGDDPEGLFAEANAVACTL-DMVMAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVLG 331
Query: 172 XXXXXXXXXXXRLPLLMAAICETQRIRSL 258
LP A + E QR +L
Sbjct: 332 PGRTPRLEDQQALPYTSAVLHEVQRFITL 360
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 68.1 bits (159), Expect = 3e-11
Identities = 30/83 (36%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F PR FL + G+
Sbjct: 241 LIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFK 300
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 301 KSNYFMPFSAGKRICVGEGLARM 323
Score = 40.3 bits (90), Expect = 0.006
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L + DMFGAG +TTS TL + LL + PE ++++EI +
Sbjct: 165 ESLIATVTDMFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRSH 224
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 225 MPYTDAVVHEVQRYIDLIPTSLPHAV 250
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 68.1 bits (159), Expect = 3e-11
Identities = 30/83 (36%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F PR FL + G+
Sbjct: 361 LIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 421 KSNYFMPFSAGKRICVGEGLARM 443
Score = 38.7 bits (86), Expect = 0.019
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L AD+ GAG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRGH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEVQRYIDLIPTSLPHAV 370
>L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 217
Score = 68.1 bits (159), Expect = 3e-11
Identities = 30/83 (36%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F PR FL + G+
Sbjct: 88 LIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFK 147
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 148 KSNYFMPFSAGKRICVGEGLARM 170
Score = 38.7 bits (86), Expect = 0.019
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L AD+ GAG +TTS TL + LL + PE ++++EI +
Sbjct: 12 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRGH 71
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 72 MPYTDAVVHEVQRYIDLIPTSLPHAV 97
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 68.1 bits (159), Expect = 3e-11
Identities = 30/83 (36%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F PR FL + G+
Sbjct: 339 LIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFK 398
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 399 KSNYFMPFSAGKRICVGEGLARM 421
Score = 38.3 bits (85), Expect = 0.025
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L AD+ GAG +TTS TL + LL + PE ++++EI +
Sbjct: 263 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGH 322
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 323 MPYTDAVVHEVQRYIDLIPTSLPHAV 348
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 68.1 bits (159), Expect = 3e-11
Identities = 30/83 (36%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F PR FL + G+
Sbjct: 361 LIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 421 KSNYFMPFSAGKRICVGEGLARM 443
Score = 38.3 bits (85), Expect = 0.025
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L AD+ GAG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEVQRYIDLIPTSLPHAV 370
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 68.1 bits (159), Expect = 3e-11
Identities = 30/83 (36%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F PR FL + G+
Sbjct: 361 LIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 421 KSNYFMPFSAGKRICVGEGLARM 443
Score = 38.3 bits (85), Expect = 0.025
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L AD+ GAG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEVQRYIDLIPTSLPHAV 370
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 68.1 bits (159), Expect = 3e-11
Identities = 30/83 (36%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F PR FL + G+
Sbjct: 361 LIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 421 KSNYFMPFSAGKRICVGEGLARM 443
Score = 38.3 bits (85), Expect = 0.025
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L AD+ GAG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEVQRYIDLIPTSLPHAV 370
>X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C
protein.
Length = 356
Score = 67.7 bits (158), Expect = 4e-11
Identities = 30/83 (36%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F PR FL + G+
Sbjct: 227 LIPTSLPHAVTCDIKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFK 286
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR+C G+ L+RM
Sbjct: 287 KSNYFMPFSAGKRICVGEGLARM 309
Score = 38.3 bits (85), Expect = 0.025
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L AD+ GAG +TTS TL + LL + PE ++++EI +
Sbjct: 151 ENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGH 210
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 211 MPYTDAVVHEVQRYIDLIPTSLPHAV 236
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 67.7 bits (158), Expect = 4e-11
Identities = 34/86 (39%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S +VP IPH D L + IPK V QW I+ D +W P +F P RFL DG+
Sbjct: 379 SSLVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGA 438
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSR 500
+ K ++ I F GKR C G+ ++R
Sbjct: 439 IDKVLSEKVIIFGMGKRKCIGETVAR 464
Score = 50.0 bits (114), Expect = 8e-06
Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXX 198
+ DE++ ++ D+FGAG DT + ++W L+Y+ + P Q +I++E ++
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 199 XXRLPLLMAAICETQRIRSLFQWEYP 276
LP + A I ET R SL + P
Sbjct: 362 RSHLPYMEAFILETFRHSSLVPFTIP 387
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VP IPH D L + IPK V QW I+ D +W P +F P RFL DG+
Sbjct: 379 SSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGA 438
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSR 500
+ K ++ I F GKR C G+ ++R
Sbjct: 439 IDKVLSEKVIIFGMGKRKCIGETIAR 464
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXX 198
+ DE++ ++ D+FGAG DT + ++W L+Y+ + P Q +I++E ++
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 199 XXRLPLLMAAICETQRIRSLFQWEYP 276
LP + A I ET R S + P
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIP 387
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VP IPH D L + IPK V QW I+ D +W P +F P RFL DG+
Sbjct: 379 SSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGA 438
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSR 500
+ K ++ I F GKR C G+ ++R
Sbjct: 439 IDKVLSEKVIIFGMGKRKCIGETIAR 464
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXX 198
+ DE++ ++ D+FGAG DT + ++W L+Y+ + P Q +I++E ++
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 199 XXRLPLLMAAICETQRIRSLFQWEYP 276
LP + A I ET R S + P
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIP 387
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VP IPH D L + IPK V QW I+ D +W P +F P RFL DG+
Sbjct: 379 SSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGA 438
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSR 500
+ K ++ I F GKR C G+ ++R
Sbjct: 439 IDKVLSEKVIIFGMGKRKCIGETIAR 464
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXX 198
+ DE++ ++ D+FGAG DT + ++W L+Y+ + P Q +I++E ++
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 199 XXRLPLLMAAICETQRIRSLFQWEYP 276
LP + A I ET R S + P
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIP 387
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VP IPH D L + IPK V QW I+ D +W P +F P RFL DG+
Sbjct: 351 SSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGA 410
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSR 500
+ K ++ I F GKR C G+ ++R
Sbjct: 411 IDKVLSEKVIIFGMGKRKCIGETIAR 436
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXX 198
+ DE++ ++ D+FGAG DT + ++W L+Y+ + P Q +I++E ++
Sbjct: 274 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 333
Query: 199 XXRLPLLMAAICETQRIRSLFQWEYP 276
LP + A I ET R S + P
Sbjct: 334 RSHLPYMEAFILETFRHSSFVPFTIP 359
>AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1
protein.
Length = 251
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VP IPH D L + IPK V QW I+ D +W P +F P RFL DG+
Sbjct: 118 SSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGA 177
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSR 500
+ K ++ I F GKR C G+ ++R
Sbjct: 178 IDKVLSEKVIIFGMGKRKCIGETIAR 203
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXX 198
+ DE++ ++ D+FGAG DT + ++W L+Y+ + P Q +I++E ++
Sbjct: 41 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 100
Query: 199 XXRLPLLMAAICETQRIRSLFQWEYP 276
LP + A I ET R S + P
Sbjct: 101 RSHLPYMEAFILETFRHSSFVPFTIP 126
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VP IPH D L + IPK V QW I+ D +W P +F P RFL DG+
Sbjct: 379 SSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGA 438
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSR 500
+ K ++ I F GKR C G+ ++R
Sbjct: 439 IDKVLSEKVIIFGMGKRKCIGETIAR 464
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXX 198
+ DE++ ++ D+FGAG DT + ++W L+Y+ + P Q +I++E ++
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 199 XXRLPLLMAAICETQRIRSLFQWEYP 276
LP + A I ET R S + P
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIP 387
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 67.3 bits (157), Expect = 5e-11
Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VP IPH D L + IPK V QW I+ D +W P +F P RFL DG+
Sbjct: 379 SSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGA 438
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSR 500
+ K ++ I F GKR C G+ ++R
Sbjct: 439 IDKVLSEKVIIFGMGKRKCIGETIAR 464
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXX 198
+ DE++ ++ D+FGAG DT + ++W L+Y+ + P Q +I++E ++
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 199 XXRLPLLMAAICETQRIRSLFQWEYP 276
LP + A I ET R S + P
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIP 387
>M12079-1|AAA52152.1| 191|Homo sapiens POR protein.
Length = 191
Score = 66.9 bits (156), Expect = 6e-11
Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VP IPH D L + IPK V QW I+ D +W P +F P RFL DG+
Sbjct: 85 SSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGA 144
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSR 500
+ K ++ I F GKR C G+ ++R
Sbjct: 145 IDKVLSEKVIIFGMGKRKCIGETVAR 170
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXX 198
+ DE++ ++ D+FGAG DT + ++W L+Y+ + P Q +I++E ++
Sbjct: 8 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 67
Query: 199 XXRLPLLMAAICETQRIRSLFQWEYP 276
LP + A I ET R S + P
Sbjct: 68 RSHLPYMEAFILETFRHSSFVPFTIP 93
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 66.9 bits (156), Expect = 6e-11
Identities = 34/86 (39%), Positives = 45/86 (52%), Gaps = 2/86 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VP IPH D L + IPK V QW I+ D +W P +F P RFL DG+
Sbjct: 379 SSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFLTPDGA 438
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSR 500
+ K ++ I F GKR C G+ ++R
Sbjct: 439 IDKVLSEKVIIFGMGKRKCIGETVAR 464
Score = 48.4 bits (110), Expect = 2e-05
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXX 198
+ DE++ ++ D+FGAG DT + ++W L+Y+ + P Q +I++E ++
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTAISWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 199 XXRLPLLMAAICETQRIRSLFQWEYP 276
LP + A I ET R S + P
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIP 387
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 66.5 bits (155), Expect = 8e-11
Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Frame = +3
Query: 249 SIIVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS 428
S VP IPH D L + IPK V QW I D +W P +F P RFL DG+
Sbjct: 379 SSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQIDHDQKLWVNPSEFLPERFLTPDGA 438
Query: 429 LLK--PQEFIPFQTGKRMCPGDELSR 500
+ K ++ I F GKR C G+ ++R
Sbjct: 439 IDKVLSEKVIIFGMGKRKCIGETIAR 464
Score = 47.2 bits (107), Expect = 5e-05
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILXXXXXXXXXX 198
+ DE++ ++ D+FGAG DT + +W L+Y+ + P Q +I++E ++
Sbjct: 302 LSDEKIINIVLDLFGAGFDTVTTATSWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSD 361
Query: 199 XXRLPLLMAAICETQRIRSLFQWEYP 276
LP + A I ET R S + P
Sbjct: 362 RSHLPYMEAFILETFRHSSFVPFTIP 387
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 66.1 bits (154), Expect = 1e-10
Identities = 28/83 (33%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+G+ H +D ++ +PK V P+ ++ DP + P F P+ FL + G
Sbjct: 365 MLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRYCFGEGLARM 447
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 66.1 bits (154), Expect = 1e-10
Identities = 28/83 (33%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+G+ H +D ++ +PK V P+ ++ DP + P F P+ FL + G
Sbjct: 365 MLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRYCFGEGLARM 447
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 66.1 bits (154), Expect = 1e-10
Identities = 28/83 (33%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+G+ H +D ++ +PK V P+ ++ DP + P F P+ FL + G
Sbjct: 365 MLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRYCFGEGLARM 447
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 66.1 bits (154), Expect = 1e-10
Identities = 28/83 (33%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+G+ H +D ++ +PK V P+ ++ DP + P F P+ FL + G
Sbjct: 365 MLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRYCFGEGLARM 447
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 66.1 bits (154), Expect = 1e-10
Identities = 28/83 (33%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+G+ H +D ++ +PK V P+ ++ DP + P F P+ FL + G
Sbjct: 365 MLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRYCFGEGLARM 447
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 66.1 bits (154), Expect = 1e-10
Identities = 28/83 (33%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+G+ H +D ++ +PK V P+ ++ DP + P F P+ FL + G
Sbjct: 365 MLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRYCFGEGLARM 447
>M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 65.3 bits (152), Expect = 2e-10
Identities = 30/83 (36%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK +I ++ + + PE F P FL + G+
Sbjct: 361 LLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKRMC G+ L+RM
Sbjct: 421 KSDYFMPFSAGKRMCMGEGLARM 443
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L + DMFGAG +TTS TL + LL + +PE ++++EI +
Sbjct: 285 ESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYIDLLPTNLPHAV 370
>BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein
protein.
Length = 310
Score = 65.3 bits (152), Expect = 2e-10
Identities = 30/83 (36%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK +I ++ + + PE F P FL + G+
Sbjct: 181 LLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK 240
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKRMC G+ L+RM
Sbjct: 241 KSDYFMPFSAGKRMCMGEGLARM 263
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L + DMFGAG +TTS TL + LL + +PE ++++EI +
Sbjct: 105 ESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSH 164
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 165 MPYTDAVVHEIQRYIDLLPTNLPHAV 190
>BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein.
Length = 431
Score = 65.3 bits (152), Expect = 2e-10
Identities = 30/83 (36%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK +I ++ + + PE F P FL + G+
Sbjct: 302 LLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK 361
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKRMC G+ L+RM
Sbjct: 362 KSDYFMPFSAGKRMCMGEGLARM 384
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L + DMFGAG +TTS TL + LL + +PE ++++EI +
Sbjct: 226 ESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSH 285
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 286 MPYTDAVVHEIQRYIDLLPTNLPHAV 311
>BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 65.3 bits (152), Expect = 2e-10
Identities = 30/83 (36%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK +I ++ + + PE F P FL + G+
Sbjct: 361 LLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKRMC G+ L+RM
Sbjct: 421 KSDYFMPFSAGKRMCMGEGLARM 443
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L + DMFGAG +TTS TL + LL + +PE ++++EI +
Sbjct: 285 ESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYIDLLPTNLPHAV 370
>BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 65.3 bits (152), Expect = 2e-10
Identities = 30/83 (36%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK +I ++ + + PE F P FL + G+
Sbjct: 361 LLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKRMC G+ L+RM
Sbjct: 421 KSDYFMPFSAGKRMCMGEGLARM 443
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L + DMFGAG +TTS TL + LL + +PE ++++EI +
Sbjct: 285 ESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYIDLLPTNLPHAV 370
>BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 65.3 bits (152), Expect = 2e-10
Identities = 30/83 (36%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK +I ++ + + PE F P FL + G+
Sbjct: 361 LLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKRMC G+ L+RM
Sbjct: 421 KSDYFMPFSAGKRMCMGEGLARM 443
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L + DMFGAG +TTS TL + LL + +PE ++++EI +
Sbjct: 285 ESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYIDLLPTNLPHAV 370
>AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 protein.
Length = 490
Score = 65.3 bits (152), Expect = 2e-10
Identities = 30/83 (36%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK +I ++ + + PE F P FL + G+
Sbjct: 361 LLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKRMC G+ L+RM
Sbjct: 421 KSDYFMPFSAGKRMCMGEGLARM 443
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L + DMFGAG +TTS TL + LL + +PE ++++EI +
Sbjct: 285 ESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYIDLLPTNLPHAV 370
>AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 18 variant protein.
Length = 490
Score = 65.3 bits (152), Expect = 2e-10
Identities = 30/83 (36%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK +I ++ + + PE F P FL + G+
Sbjct: 361 LLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKRMC G+ L+RM
Sbjct: 421 KSDYFMPFSAGKRMCMGEGLARM 443
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L + DMFGAG +TTS TL + LL + +PE ++++EI +
Sbjct: 285 ESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYIDLLPTNLPHAV 370
>L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18
protein.
Length = 490
Score = 64.9 bits (151), Expect = 2e-10
Identities = 30/83 (36%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK +I ++ + + PE F P FL + G+
Sbjct: 361 LLPTNLPHAVTCDVKFKNYLIPKGMTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKRMC G+ L+RM
Sbjct: 421 KSDYFMPFSAGKRMCMGEGLARM 443
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L + DMFGAG +TTS TL + LL + +PE ++++EI +
Sbjct: 285 ESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEIQRYIDLLPTNLPHAV 370
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 64.5 bits (150), Expect = 3e-10
Identities = 30/82 (36%), Positives = 45/82 (54%)
Frame = +3
Query: 258 VPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLK 437
V + + C++D + IPK +MV+ +A+H DP W EPE+F+P RF + S +
Sbjct: 369 VAIRLERTCMKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDS-ID 427
Query: 438 PQEFIPFQTGKRMCPGDELSRM 503
P + PF TG R C G + M
Sbjct: 428 PYIYTPFGTGPRNCIGMRFALM 449
Score = 29.9 bits (64), Expect = 8.7
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 73 AGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
AG +TTS L++ L +A P+ Q++++KEI
Sbjct: 305 AGYETTSSVLSFTLYELATHPDVQQKLQKEI 335
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS-L 431
+ P+ IPH D+ +G + + K VI WA+H + W +P++F P RFL G+ L
Sbjct: 366 VAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQL 425
Query: 432 LKPQ-EFIPFQTGKRMCPGDELSR 500
+ P ++PF G R C G+ L+R
Sbjct: 426 ISPSVSYLPFGAGPRSCIGEILAR 449
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXX 180
D + + D + + D+FGAG++TT+ + W L ++ P+ ++++ +EI +
Sbjct: 281 DQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSR 340
Query: 181 XXXXXXXXRLPLLMAAICETQRIR 252
RL LL A I E R+R
Sbjct: 341 TPTISDRNRLLLLEATIREVLRLR 364
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS-L 431
+ P+ IPH D+ +G + + K VI WA+H + W +P++F P RFL G+ L
Sbjct: 366 VAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQL 425
Query: 432 LKPQ-EFIPFQTGKRMCPGDELSR 500
+ P ++PF G R C G+ L+R
Sbjct: 426 ISPSVSYLPFGAGPRSCIGEILAR 449
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXX 180
D + + D + + D+FGAG++TT+ + W L ++ P+ ++++ +EI +
Sbjct: 281 DQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSR 340
Query: 181 XXXXXXXXRLPLLMAAICETQRIR 252
RL LL A I E R+R
Sbjct: 341 TPTISDRNRLLLLEATIREVLRLR 364
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS-L 431
+ P+ IPH D+ +G + + K VI WA+H + W +P++F P RFL G+ L
Sbjct: 366 VAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQL 425
Query: 432 LKPQ-EFIPFQTGKRMCPGDELSR 500
+ P ++PF G R C G+ L+R
Sbjct: 426 ISPSVSYLPFGAGPRSCIGEILAR 449
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXX 180
D + + D + + D+FGAG++TT+ + W L ++ P+ ++++ +EI +
Sbjct: 281 DQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSR 340
Query: 181 XXXXXXXXRLPLLMAAICETQRIR 252
RL LL A I E R+R
Sbjct: 341 TPTISDRNRLLLLEATIREVLRLR 364
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS-L 431
+ P+ IPH D+ +G + + K VI WA+H + W +P++F P RFL G+ L
Sbjct: 366 VAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQL 425
Query: 432 LKPQ-EFIPFQTGKRMCPGDELSR 500
+ P ++PF G R C G+ L+R
Sbjct: 426 ISPSVSYLPFGAGPRSCIGEILAR 449
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXX 180
D + + D + + D+FGAG++TT+ + W L ++ P+ ++++ +EI +
Sbjct: 281 DQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSR 340
Query: 181 XXXXXXXXRLPLLMAAICETQRIR 252
RL LL A I E R+R
Sbjct: 341 TPTISDRNRLLLLEATIREVLRLR 364
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS-L 431
+ P+ IPH D+ +G + + K VI WA+H + W +P++F P RFL G+ L
Sbjct: 366 VAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQL 425
Query: 432 LKPQ-EFIPFQTGKRMCPGDELSR 500
+ P ++PF G R C G+ L+R
Sbjct: 426 ISPSVSYLPFGAGPRSCIGEILAR 449
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXX 180
D + + D + + D+FGAG++TT+ + W L ++ P+ ++++ +EI +
Sbjct: 281 DQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSR 340
Query: 181 XXXXXXXXRLPLLMAAICETQRIR 252
RL LL A I E R+R
Sbjct: 341 TPTISDRNRLLLLEATIREVLRLR 364
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS-L 431
+ P+ IPH D+ +G + + K VI WA+H + W +P++F P RFL G+ L
Sbjct: 366 VAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQL 425
Query: 432 LKPQ-EFIPFQTGKRMCPGDELSR 500
+ P ++PF G R C G+ L+R
Sbjct: 426 ISPSVSYLPFGAGPRSCIGEILAR 449
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXX 180
D + + D + + D+FGAG++TT+ + W L ++ P+ ++++ +EI +
Sbjct: 281 DQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSR 340
Query: 181 XXXXXXXXRLPLLMAAICETQRIR 252
RL LL A I E R+R
Sbjct: 341 TPTISDRNRLLLLEATIREVLRLR 364
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS-L 431
+ P+ IPH D+ +G + + K VI WA+H + W +P++F P RFL G+ L
Sbjct: 366 VAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQL 425
Query: 432 LKPQ-EFIPFQTGKRMCPGDELSR 500
+ P ++PF G R C G+ L+R
Sbjct: 426 ISPSVSYLPFGAGPRSCIGEILAR 449
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXX 180
D + + D + + D+FGAG++TT+ + W L ++ P+ ++++ +EI +
Sbjct: 281 DQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSR 340
Query: 181 XXXXXXXXRLPLLMAAICETQRIR 252
RL LL A I E R+R
Sbjct: 341 TPTISDRNRLLLLEATIREVLRLR 364
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS-L 431
+ P+ IPH D+ +G + + K VI WA+H + W +P++F P RFL G+ L
Sbjct: 366 VAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQL 425
Query: 432 LKPQ-EFIPFQTGKRMCPGDELSR 500
+ P ++PF G R C G+ L+R
Sbjct: 426 ISPSVSYLPFGAGPRSCIGEILAR 449
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXX 180
D + + D + + D+FGAG++TT+ + W L ++ P+ ++++ +EI +
Sbjct: 281 DQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSR 340
Query: 181 XXXXXXXXRLPLLMAAICETQRIR 252
RL LL A I E R+R
Sbjct: 341 TPTISDRNRLLLLEATIREVLRLR 364
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 64.1 bits (149), Expect = 4e-10
Identities = 30/84 (35%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGS-L 431
+ P+ IPH D+ +G + + K VI WA+H + W +P++F P RFL G+ L
Sbjct: 366 VAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQL 425
Query: 432 LKPQ-EFIPFQTGKRMCPGDELSR 500
+ P ++PF G R C G+ L+R
Sbjct: 426 ISPSVSYLPFGAGPRSCIGEILAR 449
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Frame = +1
Query: 10 DPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXX 180
D + + D + + D+FGAG++TT+ + W L ++ P+ ++++ +EI +
Sbjct: 281 DQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSR 340
Query: 181 XXXXXXXXRLPLLMAAICETQRIR 252
RL LL A I E R+R
Sbjct: 341 TPTISDRNRLLLLEATIREVLRLR 364
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 26/83 (31%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ DP+ + P+ F P+ FL + G
Sbjct: 365 VIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRNCFGEGLARM 447
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 62.9 bits (146), Expect = 1e-09
Identities = 26/83 (31%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ DP+ + P+ F P+ FL + G
Sbjct: 319 VIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFK 378
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 379 KSDAFVPFSIGKRNCFGEGLARM 401
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 62.9 bits (146), Expect = 1e-09
Identities = 26/83 (31%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ DP+ + P+ F P+ FL + G
Sbjct: 360 VIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFK 419
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 420 KSDAFVPFSIGKRNCFGEGLARM 442
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 26/83 (31%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ DP+ + P+ F P+ FL + G
Sbjct: 365 VIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRNCFGEGLARM 447
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 26/83 (31%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ DP+ + P+ F P+ FL G
Sbjct: 365 VIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRYCFGEGLARM 447
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/82 (36%), Positives = 44/82 (53%)
Frame = +3
Query: 258 VPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLK 437
V + + C +D + IPK +MV+ +A+H DP W EPE+F+P RF + S +
Sbjct: 369 VAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDS-ID 427
Query: 438 PQEFIPFQTGKRMCPGDELSRM 503
P + PF TG R C G + M
Sbjct: 428 PYIYTPFGTGPRNCIGMRFALM 449
Score = 29.9 bits (64), Expect = 8.7
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 73 AGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
AG +TTS L++ L +A P+ Q++++KEI
Sbjct: 305 AGYETTSSVLSFTLYELATHPDVQQKLQKEI 335
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 26/83 (31%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ DP+ + P+ F P+ FL G
Sbjct: 365 VIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRYCFGEGLARM 447
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 26/83 (31%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ DP+ + P+ F P+ FL + G
Sbjct: 365 VIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRNCFGEGLARM 447
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 26/83 (31%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ DP+ + P+ F P+ FL + G
Sbjct: 365 VIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRNCFGEGLARM 447
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 26/83 (31%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ DP+ + P+ F P+ FL + G
Sbjct: 365 VIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRNCFGEGLARM 447
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 26/83 (31%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ DP+ + P+ F P+ FL + G
Sbjct: 365 VIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRNCFGEGLARM 447
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/82 (36%), Positives = 44/82 (53%)
Frame = +3
Query: 258 VPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLK 437
V + + C +D + IPK +MV+ +A+H DP W EPE+F+P RF + S +
Sbjct: 369 VAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDS-ID 427
Query: 438 PQEFIPFQTGKRMCPGDELSRM 503
P + PF TG R C G + M
Sbjct: 428 PYIYTPFGTGPRNCIGMRFALM 449
Score = 29.9 bits (64), Expect = 8.7
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 73 AGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
AG +TTS L++ L +A P+ Q++++KEI
Sbjct: 305 AGYETTSSVLSFTLYELATHPDVQQKLQKEI 335
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/82 (36%), Positives = 44/82 (53%)
Frame = +3
Query: 258 VPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLK 437
V + + C +D + IPK +MV+ +A+H DP W EPE+F+P RF + S +
Sbjct: 40 VAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDS-ID 98
Query: 438 PQEFIPFQTGKRMCPGDELSRM 503
P + PF TG R C G + M
Sbjct: 99 PYIYTPFGTGPRNCIGMRFALM 120
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/82 (36%), Positives = 44/82 (53%)
Frame = +3
Query: 258 VPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLK 437
V + + C +D + IPK +MV+ +A+H DP W EPE+F+P RF + S +
Sbjct: 27 VAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDS-ID 85
Query: 438 PQEFIPFQTGKRMCPGDELSRM 503
P + PF TG R C G + M
Sbjct: 86 PYIYTPFGTGPRNCIGMRFALM 107
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 62.9 bits (146), Expect = 1e-09
Identities = 26/83 (31%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ DP+ + P+ F P+ FL + G
Sbjct: 365 VIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRNCFGEGLARM 447
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 62.9 bits (146), Expect = 1e-09
Identities = 30/82 (36%), Positives = 44/82 (53%)
Frame = +3
Query: 258 VPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLK 437
V + + C +D + IPK +MV+ +A+H DP W EPE+F+P RF + S +
Sbjct: 369 VAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKDS-ID 427
Query: 438 PQEFIPFQTGKRMCPGDELSRM 503
P + PF TG R C G + M
Sbjct: 428 PYIYTPFGTGPRNCIGMRFALM 449
Score = 29.9 bits (64), Expect = 8.7
Identities = 13/31 (41%), Positives = 22/31 (70%)
Frame = +1
Query: 73 AGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
AG +TTS L++ L +A P+ Q++++KEI
Sbjct: 305 AGYETTSSVLSFTLYELATHPDVQQKLQKEI 335
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 62.1 bits (144), Expect = 2e-09
Identities = 28/83 (33%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F P FL + G+
Sbjct: 348 LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK 407
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F+PF GKR+C G+ L+ M
Sbjct: 408 KSKYFMPFSAGKRICVGEALAGM 430
Score = 39.5 bits (88), Expect = 0.011
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L D+FGAG +TTS TL + LL + PE ++++EI +
Sbjct: 272 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSH 331
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 332 MPYTDAVVHEVQRYIDLLPTSLPHAV 357
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 62.1 bits (144), Expect = 2e-09
Identities = 28/83 (33%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F P FL + G+
Sbjct: 254 LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK 313
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F+PF GKR+C G+ L+ M
Sbjct: 314 KSKYFMPFSAGKRICVGEALAGM 336
Score = 39.5 bits (88), Expect = 0.011
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L D+FGAG +TTS TL + LL + PE ++++EI +
Sbjct: 178 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSH 237
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 238 MPYTDAVVHEVQRCIDLLPTSLPHAV 263
>L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein.
Length = 169
Score = 62.1 bits (144), Expect = 2e-09
Identities = 28/83 (33%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F P FL + G+
Sbjct: 40 LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK 99
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F+PF GKR+C G+ L+ M
Sbjct: 100 KSKYFMPFSAGKRICVGEALAGM 122
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 62.1 bits (144), Expect = 2e-09
Identities = 28/83 (33%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F P FL + G+
Sbjct: 358 LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK 417
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F+PF GKR+C G+ L+ M
Sbjct: 418 KSKYFMPFSAGKRICVGEALAGM 440
Score = 39.5 bits (88), Expect = 0.011
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L D+FGAG +TTS TL + LL + PE ++++EI +
Sbjct: 282 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSH 341
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 342 MPYTDAVVHEVQRYIDLLPTSLPHAV 367
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 62.1 bits (144), Expect = 2e-09
Identities = 28/83 (33%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F P FL + G+
Sbjct: 361 LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F+PF GKR+C G+ L+ M
Sbjct: 421 KSKYFMPFSAGKRICVGEALAGM 443
Score = 39.5 bits (88), Expect = 0.011
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L D+FGAG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEVQRYIDLLPTSLPHAV 370
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 62.1 bits (144), Expect = 2e-09
Identities = 28/83 (33%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F P FL + G+
Sbjct: 361 LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F+PF GKR+C G+ L+ M
Sbjct: 421 KSKYFMPFSAGKRICVGEALAGM 443
Score = 39.5 bits (88), Expect = 0.011
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L D+FGAG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEVQRYIDLLPTSLPHAV 370
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 62.1 bits (144), Expect = 2e-09
Identities = 28/83 (33%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F P FL + G+
Sbjct: 361 LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F+PF GKR+C G+ L+ M
Sbjct: 421 KSKYFMPFSAGKRICVGEALAGM 443
Score = 39.5 bits (88), Expect = 0.011
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L D+FGAG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEVQRYIDLLPTSLPHAV 370
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 62.1 bits (144), Expect = 2e-09
Identities = 28/83 (33%), Positives = 43/83 (51%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F P FL + G+
Sbjct: 361 LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFK 420
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F+PF GKR+C G+ L+ M
Sbjct: 421 KSKYFMPFSAGKRICVGEALAGM 443
Score = 39.5 bits (88), Expect = 0.011
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L D+FGAG +TTS TL + LL + PE ++++EI +
Sbjct: 285 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSH 344
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 345 MPYTDAVVHEVQRYIDLLPTSLPHAV 370
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 61.7 bits (143), Expect = 2e-09
Identities = 27/83 (32%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+G+ H +D ++ +PK V P+ + DP + P+ P+ FL + G
Sbjct: 365 MLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSELRDPRFFSNPQDCSPQHFLDEKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF GKR C G+ L+RM
Sbjct: 425 KSDAFVPFSIGKRYCFGEGLARM 447
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 359 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 414
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 415 KNSRALAFGCGARVCLGEPLARL 437
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 282 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDHA 341
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 342 RLPLLNATIAEVLRLRPVVPLALP 365
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 359 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 414
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 415 KNSRALAFGCGARVCLGEPLARL 437
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 282 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 341
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 342 RLPLLNATIAEVLRLRPVVPLALP 365
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 359 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 414
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 415 KNSRALAFGCGARVCLGEPLARL 437
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 282 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 341
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 342 RLPLLNATIAEVLRLRPVVPLALP 365
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 359 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 414
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 415 KNSRALAFGCGARVCLGEPLARL 437
Score = 38.7 bits (86), Expect = 0.019
Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
LH D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 282 LHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 341
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 342 RLPLLNATIAEVLRLRPVVPLALP 365
>M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein.
Length = 230
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 94 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 149
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 150 KNSRALAFGCGARVCLGEPLARL 172
Score = 34.7 bits (76), Expect = 0.30
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ E Q+ +++E+
Sbjct: 17 VHMAAVDLLIGGTETTANTLSWAVVFLLHHLEIQQRLQEELDHELGPGASSSRVPYKDRA 76
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL+A I E R+R + P
Sbjct: 77 RLPLLIATIAEVLRLRPVVPLALP 100
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 464
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 328 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 383
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 384 KNSRALAFGCGARVCLGEPLARL 406
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 251 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 310
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 311 RLPLLNATIAEVLRLRPVVPLALP 334
>BC128535-1|AAI28536.1| 143|Homo sapiens CYP21A2 protein protein.
Length = 143
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 7 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 62
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 63 KNSRALAFGCGARVCLGEPLARL 85
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 359 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 414
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 415 KNSRALAFGCGARVCLGEPLARL 437
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 282 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 341
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 342 RLPLLNATIAEVLRLRPVVPLALP 365
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 37.1 bits (82), Expect = 0.057
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLFHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 35.5 bits (78), Expect = 0.17
Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEILXXXXXXXXXXXX------ 204
+H D+ G + T+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTENTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGTHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 329 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 384
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 385 KNSRALAFGCGARVCLGEPLARL 407
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 252 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 311
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 312 RLPLLNATIAEVLRLRPVVPLALP 335
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 359 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 414
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 415 KNSRALAFGCGARVCLGEPLARL 437
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 282 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 341
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 342 RLPLLNATIAEVLRLRPVVPLALP 365
>AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 329 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 384
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 385 KNSRALAFGCGARVCLGEPLARL 407
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 252 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 311
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 312 RLPLLNATIAEVLRLRPVVPLALP 335
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 359 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 414
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 415 KNSRALAFGCGARVCLGEPLARL 437
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 282 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 341
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 342 RLPLLNATIAEVLRLRPVVPLALP 365
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 359 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 414
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 415 KNSRALAFGCGARVCLGEPLARL 437
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 282 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 341
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 342 RLPLLNATIAEVLRLRPVVPLALP 365
>AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 329 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 384
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 385 KNSRALAFGCGARVCLGEPLARL 407
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 252 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 311
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 312 RLPLLNATIAEVLRLRPVVPLALP 335
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 359 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 414
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 415 KNSRALAFGCGARVCLGEPLARL 437
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 282 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 341
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 342 RLPLLNATIAEVLRLRPVVPLALP 365
>AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens
cDNA FLJ30054 fis, clone ADRGL1000160, highly similar to
CYTOCHROME P450 XXIB (EC 1.14.99.10). ).
Length = 465
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 329 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 384
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 385 KNSRALAFGCGARVCLGEPLARL 407
Score = 37.9 bits (84), Expect = 0.033
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Frame = +1
Query: 28 MRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXX 189
+++ +H D+ G +TT+ TL+W +++ PE Q+ +++E+
Sbjct: 247 LQEGHVHMAAVDLLIGGTETTANTLSWAAVFLLHHPEIQQRLQEELDHELGPGASSSRVP 306
Query: 190 XXXXXRLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 307 YKDRARLPLLNATIAEVLRLRPVVPLALP 335
>AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 403
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 267 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 322
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 323 KNSRALAFGCGARVCLGEPLARL 345
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 190 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 249
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 250 RLPLLNATIAEVLRLRPVVPLALP 273
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 60.5 bits (140), Expect = 5e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 359 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 414
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 415 KNSRALAFGCGARVCLGEPLARL 437
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 282 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 341
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 342 RLPLLNATIAEVLRLRPVVPLALP 365
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 60.1 bits (139), Expect = 7e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 437 SGPRNCIGMRFALM 450
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 60.1 bits (139), Expect = 7e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 437 SGPRNCIGMRFALM 450
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 60.1 bits (139), Expect = 7e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 437 SGPRNCIGMRFALM 450
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 60.1 bits (139), Expect = 7e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 437 SGPRNCIGMRFALM 450
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 60.1 bits (139), Expect = 7e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 437 SGPRNCIGMRFALM 450
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 60.1 bits (139), Expect = 7e-09
Identities = 29/83 (34%), Positives = 45/83 (54%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHCTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G R+C G+ L+R+
Sbjct: 414 KNSRALAFGCGARVCLGEPLARL 436
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 60.1 bits (139), Expect = 7e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 227 CKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 286
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 287 SGPRNCIGMRFALM 300
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 60.1 bits (139), Expect = 7e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 304 CKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 363
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 364 SGPRNCIGMRFALM 377
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 60.1 bits (139), Expect = 7e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 437 SGPRNCIGMRFALM 450
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 60.1 bits (139), Expect = 7e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 437 SGPRNCIGMRFALM 450
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 60.1 bits (139), Expect = 7e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 437 SGPRNCIGMRFALM 450
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 60.1 bits (139), Expect = 7e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 437 SGPRNCIGMRFALM 450
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 59.7 bits (138), Expect = 9e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFG 436
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 437 SGPRNCIGMRFALM 450
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 59.7 bits (138), Expect = 9e-09
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 376 CKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFG 435
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 436 SGPRNCIGMRFALM 449
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 59.3 bits (137), Expect = 1e-08
Identities = 27/83 (32%), Positives = 42/83 (50%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F P FL + +
Sbjct: 356 LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGDNFK 415
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F+PF GKR+C G+ L+ M
Sbjct: 416 KSKYFMPFSAGKRICVGEALAGM 438
Score = 39.5 bits (88), Expect = 0.011
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L D+FGAG +TTS TL + LL + PE ++++EI +
Sbjct: 280 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSH 339
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 340 MPYTDAVVHEVQRCIDLLPTSLPHAV 365
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 59.3 bits (137), Expect = 1e-08
Identities = 27/83 (32%), Positives = 42/83 (50%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P +PH D NY IPK ++ ++ D + PE F P FL + +
Sbjct: 356 LLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGDNFK 415
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F+PF GKR+C G+ L+ M
Sbjct: 416 KSKYFMPFSAGKRICVGEALAGM 438
Score = 39.5 bits (88), Expect = 0.011
Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 3/86 (3%)
Frame = +1
Query: 37 EQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXR 207
E L D+FGAG +TTS TL + LL + PE ++++EI +
Sbjct: 280 ESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSH 339
Query: 208 LPLLMAAICETQRIRSLFQWEYPMVV 285
+P A + E QR L P V
Sbjct: 340 MPYTDAVVHEVQRCIDLLPTSLPHAV 365
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 58.8 bits (136), Expect = 2e-08
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 437 SGPRNCIGMRFALM 450
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 58.8 bits (136), Expect = 2e-08
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 378 CKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 437
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 438 SGPRNCIGMRFALM 451
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 58.8 bits (136), Expect = 2e-08
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ +A+H DP W EPEKF P RF ++ + P + PF
Sbjct: 378 CKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 437
Query: 462 TGKRMCPGDELSRM 503
+G R C G + M
Sbjct: 438 SGPRNCIGMRFALM 451
>AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 variant protein.
Length = 336
Score = 58.8 bits (136), Expect = 2e-08
Identities = 27/76 (35%), Positives = 37/76 (48%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP +PH D Y IPK +V+P ++ D + +PEKFKP FL ++G
Sbjct: 259 LVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFK 318
Query: 435 KPQEFIPFQTGKRMCP 482
F PF TG P
Sbjct: 319 YSDYFKPFSTGSLCSP 334
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 3/77 (3%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI---LXXXXXXXXXXXXRLPLLMA 225
+AD+F AG +TTS TL + LL + +PE +E++ +EI + +P + A
Sbjct: 189 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDA 248
Query: 226 AICETQRIRSLFQWEYP 276
+ E QR +L P
Sbjct: 249 VVHEIQRFITLVPSNLP 265
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 58.0 bits (134), Expect = 3e-08
Identities = 23/72 (31%), Positives = 38/72 (52%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
ED + YR+ K + + +A+H DP + PE+F+P RF ++ P ++PF G
Sbjct: 404 EDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 463
Query: 468 KRMCPGDELSRM 503
R C G + + M
Sbjct: 464 PRNCIGQKFAVM 475
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 58.0 bits (134), Expect = 3e-08
Identities = 23/72 (31%), Positives = 38/72 (52%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
ED + YR+ K + + +A+H DP + PE+F+P RF ++ P ++PF G
Sbjct: 404 EDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 463
Query: 468 KRMCPGDELSRM 503
R C G + + M
Sbjct: 464 PRNCIGQKFAVM 475
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 58.0 bits (134), Expect = 3e-08
Identities = 23/72 (31%), Positives = 38/72 (52%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
ED + YR+ K + + +A+H DP + PE+F+P RF ++ P ++PF G
Sbjct: 382 EDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 441
Query: 468 KRMCPGDELSRM 503
R C G + + M
Sbjct: 442 PRNCIGQKFAVM 453
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 58.0 bits (134), Expect = 3e-08
Identities = 23/72 (31%), Positives = 38/72 (52%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
ED + YR+ K + + +A+H DP + PE+F+P RF ++ P ++PF G
Sbjct: 404 EDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAG 463
Query: 468 KRMCPGDELSRM 503
R C G + + M
Sbjct: 464 PRNCIGQKFAVM 475
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 57.6 bits (133), Expect = 4e-08
Identities = 28/83 (33%), Positives = 44/83 (53%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
+VP+ +PH + + Y IP+ ++IP H+D VWE P +F P RFL + G
Sbjct: 358 VVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL-EPG--- 413
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K + F G +C G+ L+R+
Sbjct: 414 KNSRALAFGCGAPVCLGEPLARL 436
Score = 37.5 bits (83), Expect = 0.043
Identities = 23/84 (27%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Frame = +1
Query: 43 LHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI------LXXXXXXXXXXXX 204
+H D+ G +TT+ TL+W ++++ PE Q+ +++E+
Sbjct: 281 VHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRA 340
Query: 205 RLPLLMAAICETQRIRSLFQWEYP 276
RLPLL A I E R+R + P
Sbjct: 341 RLPLLNATIAEVLRLRPVVPLALP 364
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 57.6 bits (133), Expect = 4e-08
Identities = 25/68 (36%), Positives = 36/68 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ + +H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPG 485
+G R C G
Sbjct: 437 SGPRNCIG 444
Score = 30.3 bits (65), Expect = 6.6
Identities = 12/31 (38%), Positives = 22/31 (70%)
Frame = +1
Query: 73 AGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
AG +TTS L++ + +A P+ Q++++KEI
Sbjct: 305 AGYETTSSVLSFIIYELATHPDVQQKVQKEI 335
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 57.6 bits (133), Expect = 4e-08
Identities = 25/68 (36%), Positives = 36/68 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ + +H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPG 485
+G R C G
Sbjct: 437 SGPRNCIG 444
Score = 30.3 bits (65), Expect = 6.6
Identities = 12/31 (38%), Positives = 22/31 (70%)
Frame = +1
Query: 73 AGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
AG +TTS L++ + +A P+ Q++++KEI
Sbjct: 305 AGYETTSSVLSFIIYELATHPDVQQKVQKEI 335
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 57.6 bits (133), Expect = 4e-08
Identities = 25/68 (36%), Positives = 36/68 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ + +H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPG 485
+G R C G
Sbjct: 437 SGPRNCIG 444
Score = 30.3 bits (65), Expect = 6.6
Identities = 12/31 (38%), Positives = 22/31 (70%)
Frame = +1
Query: 73 AGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
AG +TTS L++ + +A P+ Q++++KEI
Sbjct: 305 AGYETTSSVLSFIIYELATHPDVQQKVQKEI 335
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 57.6 bits (133), Expect = 4e-08
Identities = 25/68 (36%), Positives = 36/68 (52%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQ 461
C +D + IPK +V+ + +H DP W EPEKF P RF ++ + P + PF
Sbjct: 377 CKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436
Query: 462 TGKRMCPG 485
+G R C G
Sbjct: 437 SGPRNCIG 444
Score = 30.3 bits (65), Expect = 6.6
Identities = 12/31 (38%), Positives = 22/31 (70%)
Frame = +1
Query: 73 AGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
AG +TTS L++ + +A P+ Q++++KEI
Sbjct: 305 AGYETTSSVLSFIIYELATHPDVQQKVQKEI 335
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 56.4 bits (130), Expect = 9e-08
Identities = 28/74 (37%), Positives = 40/74 (54%), Gaps = 1/74 (1%)
Frame = +3
Query: 279 GCIEDAYLGNYR-IPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIP 455
GC +D L + R IPK + +AIH +P+VW +PE + P RF ++ P FIP
Sbjct: 401 GCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIP 460
Query: 456 FQTGKRMCPGDELS 497
F G R C G + +
Sbjct: 461 FSAGPRNCIGQKFA 474
Score = 33.9 bits (74), Expect = 0.53
Identities = 17/34 (50%), Positives = 22/34 (64%)
Frame = +1
Query: 64 MFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
MFG G DTT+ L+W L +A PE QE R+E+
Sbjct: 326 MFG-GHDTTASGLSWVLYNLARHPEYQERCRQEV 358
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 56.0 bits (129), Expect = 1e-07
Identities = 27/69 (39%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKN-AMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPF 458
C +D + IPK A+++P+ +A+H DP W EPEKF P RF ++ + +IPF
Sbjct: 267 CKKDIEINGVFIPKGLAVMVPI-YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPF 325
Query: 459 QTGKRMCPG 485
G R C G
Sbjct: 326 GAGPRNCIG 334
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 56.0 bits (129), Expect = 1e-07
Identities = 27/69 (39%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKN-AMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPF 458
C +D + IPK A+++P+ +A+H DP W EPEKF P RF ++ + +IPF
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPI-YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPF 435
Query: 459 QTGKRMCPG 485
G R C G
Sbjct: 436 GAGPRNCIG 444
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 56.0 bits (129), Expect = 1e-07
Identities = 27/69 (39%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKN-AMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPF 458
C +D + IPK A+++P+ +A+H DP W EPEKF P RF ++ + +IPF
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPI-YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPF 435
Query: 459 QTGKRMCPG 485
G R C G
Sbjct: 436 GAGPRNCIG 444
>AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens
cDNA FLJ20359 fis, clone HEP16626. ).
Length = 408
Score = 56.0 bits (129), Expect = 1e-07
Identities = 23/68 (33%), Positives = 37/68 (54%)
Frame = +3
Query: 270 IPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEF 449
+P D LG + +PK VIPL ++ +D W+ P +F P FL +G +K + F
Sbjct: 308 VPRCTAADTQLGGFLLPKGTPVIPLLTSVLLDETQWQTPGQFNPGHFLDANGHFVKREAF 367
Query: 450 IPFQTGKR 473
+PF G++
Sbjct: 368 LPFSAGQQ 375
Score = 38.3 bits (85), Expect = 0.025
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 3/89 (3%)
Frame = +1
Query: 1 ESGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKE---ILX 171
+ DP L+ + L DM AG +TTS TL W L M P+ Q +++E +L
Sbjct: 217 QGDDPEGLFAEANAVACTL-DMVMAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVLG 275
Query: 172 XXXXXXXXXXXRLPLLMAAICETQRIRSL 258
LP A + E QR +L
Sbjct: 276 PGRTPRLEDQQALPYTSAVLHEVQRFITL 304
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 56.0 bits (129), Expect = 1e-07
Identities = 27/69 (39%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKN-AMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPF 458
C +D + IPK A+++P+ +A+H DP W EPEKF P RF ++ + +IPF
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPI-YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPF 435
Query: 459 QTGKRMCPG 485
G R C G
Sbjct: 436 GAGPRNCIG 444
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 56.0 bits (129), Expect = 1e-07
Identities = 27/69 (39%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKN-AMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPF 458
C +D + IPK A+++P+ +A+H DP W EPEKF P RF ++ + +IPF
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPI-YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPF 435
Query: 459 QTGKRMCPG 485
G R C G
Sbjct: 436 GAGPRNCIG 444
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 56.0 bits (129), Expect = 1e-07
Identities = 27/69 (39%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKN-AMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPF 458
C +D + IPK A+++P+ +A+H DP W EPEKF P RF ++ + +IPF
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPI-YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPF 435
Query: 459 QTGKRMCPG 485
G R C G
Sbjct: 436 GAGPRNCIG 444
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 56.0 bits (129), Expect = 1e-07
Identities = 27/69 (39%), Positives = 39/69 (56%), Gaps = 1/69 (1%)
Frame = +3
Query: 282 CIEDAYLGNYRIPKN-AMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPF 458
C +D + IPK A+++P+ +A+H DP W EPEKF P RF ++ + +IPF
Sbjct: 377 CKKDIEINGVFIPKGLAVMVPI-YALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPF 435
Query: 459 QTGKRMCPG 485
G R C G
Sbjct: 436 GAGPRNCIG 444
>AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450
epoxygenase protein.
Length = 339
Score = 55.6 bits (128), Expect = 2e-07
Identities = 27/54 (50%), Positives = 38/54 (70%)
Frame = +1
Query: 4 SGDPTALYMRDEQLHFLLADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
+G+PT+ + +E L D+F AG +TTS TL W LLYMAL+PE QE+++ EI
Sbjct: 258 TGNPTSSF-HEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQVEI 310
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 55.2 bits (127), Expect = 2e-07
Identities = 24/83 (28%), Positives = 41/83 (49%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ D + P F P+ FL + G
Sbjct: 365 VIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDLRFFSNPRDFNPQHFLGEKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF KR C G+ L+RM
Sbjct: 425 KRDAFVPFSIRKRNCFGEGLARM 447
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
+D ++G+Y IPKN +V +A DP + EP F+P R+L +G P +PF G
Sbjct: 393 KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARWLG-EGPTPHPFASLPFGFG 451
Query: 468 KRMCPGDELSRM 503
KR C G L+ +
Sbjct: 452 KRSCMGRRLAEL 463
Score = 31.9 bits (69), Expect = 2.1
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEIL-----XXXXXXXXXXXXRLPLL 219
+ ++ AG+DT S TL+W L ++ PE Q + EI +LPLL
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 220 MAAICETQRI 249
A + E R+
Sbjct: 371 KAVVKEVLRL 380
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
+D ++G+Y IPKN +V +A DP + EP F+P R+L +G P +PF G
Sbjct: 393 KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARWLG-EGPTPHPFASLPFGFG 451
Query: 468 KRMCPGDELSRM 503
KR C G L+ +
Sbjct: 452 KRSCMGRRLAEL 463
Score = 31.9 bits (69), Expect = 2.1
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEIL-----XXXXXXXXXXXXRLPLL 219
+ ++ AG+DT S TL+W L ++ PE Q + EI +LPLL
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 220 MAAICETQRI 249
A + E R+
Sbjct: 371 KAVVKEVLRL 380
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
+D ++G+Y IPKN +V +A DP + EP F+P R+L +G P +PF G
Sbjct: 393 KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARWLG-EGPTPHPFASLPFGFG 451
Query: 468 KRMCPGDELSRM 503
KR C G L+ +
Sbjct: 452 KRSCMGRRLAEL 463
Score = 31.9 bits (69), Expect = 2.1
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEIL-----XXXXXXXXXXXXRLPLL 219
+ ++ AG+DT S TL+W L ++ PE Q + EI +LPLL
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 220 MAAICETQRI 249
A + E R+
Sbjct: 371 KAVVKEVLRL 380
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
+D ++G+Y IPKN +V +A DP + EP F+P R+L +G P +PF G
Sbjct: 393 KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARWLG-EGPTPHPFASLPFGFG 451
Query: 468 KRMCPGDELSRM 503
KR C G L+ +
Sbjct: 452 KRSCMGRRLAEL 463
Score = 31.9 bits (69), Expect = 2.1
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEIL-----XXXXXXXXXXXXRLPLL 219
+ ++ AG+DT S TL+W L ++ PE Q + EI +LPLL
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 220 MAAICETQRI 249
A + E R+
Sbjct: 371 KAVVKEVLRL 380
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
+D ++G+Y IPKN +V +A DP + EP F+P R+L +G P +PF G
Sbjct: 393 KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARWLG-EGPTPHPFASLPFGFG 451
Query: 468 KRMCPGDELSRM 503
KR C G L+ +
Sbjct: 452 KRSCMGRRLAEL 463
Score = 31.9 bits (69), Expect = 2.1
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEIL-----XXXXXXXXXXXXRLPLL 219
+ ++ AG+DT S TL+W L ++ PE Q + EI +LPLL
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 220 MAAICETQRI 249
A + E R+
Sbjct: 371 KAVVKEVLRL 380
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
+D ++G+Y IPKN +V +A DP + EP F+P R+L +G P +PF G
Sbjct: 393 KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARWLG-EGPTPHPFASLPFGFG 451
Query: 468 KRMCPGDELSRM 503
KR C G L+ +
Sbjct: 452 KRSCMGRRLAEL 463
Score = 31.9 bits (69), Expect = 2.1
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEIL-----XXXXXXXXXXXXRLPLL 219
+ ++ AG+DT S TL+W L ++ PE Q + EI +LPLL
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 220 MAAICETQRI 249
A + E R+
Sbjct: 371 KAVVKEVLRL 380
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
+D ++G+Y IPKN +V +A DP + EP F+P R+L +G P +PF G
Sbjct: 393 KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARWLG-EGPTPHPFASLPFGFG 451
Query: 468 KRMCPGDELSRM 503
KR C G L+ +
Sbjct: 452 KRSCMGRRLAEL 463
Score = 31.9 bits (69), Expect = 2.1
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEIL-----XXXXXXXXXXXXRLPLL 219
+ ++ AG+DT S TL+W L ++ PE Q + EI +LPLL
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 220 MAAICETQRI 249
A + E R+
Sbjct: 371 KAVVKEVLRL 380
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
+D ++G+Y IPKN +V +A DP + EP F+P R+L +G P +PF G
Sbjct: 393 KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARWLG-EGPTPHPFASLPFGFG 451
Query: 468 KRMCPGDELSRM 503
KR C G L+ +
Sbjct: 452 KRSCMGRRLAEL 463
Score = 31.9 bits (69), Expect = 2.1
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEIL-----XXXXXXXXXXXXRLPLL 219
+ ++ AG+DT S TL+W L ++ PE Q + EI +LPLL
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 220 MAAICETQRI 249
A + E R+
Sbjct: 371 KAVVKEVLRL 380
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 55.2 bits (127), Expect = 2e-07
Identities = 27/72 (37%), Positives = 40/72 (55%)
Frame = +3
Query: 288 EDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTG 467
+D ++G+Y IPKN +V +A DP + EP F+P R+L +G P +PF G
Sbjct: 393 KDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRPARWLG-EGPTPHPFASLPFGFG 451
Query: 468 KRMCPGDELSRM 503
KR C G L+ +
Sbjct: 452 KRSCMGRRLAEL 463
Score = 31.9 bits (69), Expect = 2.1
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Frame = +1
Query: 55 LADMFGAGLDTTSVTLAWFLLYMALFPEEQEEIRKEIL-----XXXXXXXXXXXXRLPLL 219
+ ++ AG+DT S TL+W L ++ PE Q + EI +LPLL
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 220 MAAICETQRI 249
A + E R+
Sbjct: 371 KAVVKEVLRL 380
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 54.8 bits (126), Expect = 3e-07
Identities = 24/83 (28%), Positives = 41/83 (49%)
Frame = +3
Query: 255 IVPVGIPHGCIEDAYLGNYRIPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLL 434
++P+ + +D ++ +PK V P+ ++ D + P F P+ FL + G
Sbjct: 365 VIPMSLARRVKKDTKFRDFFLPKGIEVFPMLGSVLRDLRFFSNPRDFNPQHFLGEKGQFK 424
Query: 435 KPQEFIPFQTGKRMCPGDELSRM 503
K F+PF KR C G+ L+RM
Sbjct: 425 KRDAFVPFSIRKRNCFGEGLARM 447
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 53.6 bits (123), Expect = 6e-07
Identities = 22/61 (36%), Positives = 31/61 (50%)
Frame = +3
Query: 315 IPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTGKRMCPGDEL 494
+P V WA+H +P WE+P+ F P RF ++ + P FIPF G R C G
Sbjct: 398 LPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHF 457
Query: 495 S 497
+
Sbjct: 458 A 458
Score = 35.5 bits (78), Expect = 0.17
Identities = 15/31 (48%), Positives = 20/31 (64%)
Frame = +1
Query: 73 AGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
AG DTTS ++W L +A +PE Q+ R EI
Sbjct: 314 AGHDTTSSAISWILYCLAKYPEHQQRCRDEI 344
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 53.6 bits (123), Expect = 6e-07
Identities = 22/61 (36%), Positives = 31/61 (50%)
Frame = +3
Query: 315 IPKNAMVIPLQWAIHMDPNVWEEPEKFKPRRFLAQDGSLLKPQEFIPFQTGKRMCPGDEL 494
+P V WA+H +P WE+P+ F P RF ++ + P FIPF G R C G
Sbjct: 398 LPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHF 457
Query: 495 S 497
+
Sbjct: 458 A 458
Score = 35.5 bits (78), Expect = 0.17
Identities = 15/31 (48%), Positives = 20/31 (64%)
Frame = +1
Query: 73 AGLDTTSVTLAWFLLYMALFPEEQEEIRKEI 165
AG DTTS ++W L +A +PE Q+ R EI
Sbjct: 314 AGHDTTSSAISWILYCLAKYPEHQQRCRDEI 344
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,082,494
Number of Sequences: 237096
Number of extensions: 2530677
Number of successful extensions: 5441
Number of sequences better than 10.0: 436
Number of HSP's better than 10.0 without gapping: 4873
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5326
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7647512560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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