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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= prgv0049
         (691 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X74331-1|CAA52378.1|  509|Homo sapiens DNA primase (p58 subunit)...    91   5e-18
BC064931-1|AAH64931.1|  509|Homo sapiens primase, DNA, polypepti...    91   5e-18
AL162579-2|CAI40673.1|  340|Homo sapiens primase, polypeptide 2A...    79   1e-14
AL121975-2|CAI42767.1|  340|Homo sapiens primase, polypeptide 2A...    79   1e-14
AL121958-1|CAC03545.2|  340|Homo sapiens primase, polypeptide 2A...    79   1e-14
BC150332-1|AAI50333.1| 1011|Homo sapiens CAP-GLY domain containi...    30   8.9  
AF041059-1|AAB96784.1|  419|Homo sapiens similar to KIAA0291: DD...    30   8.9  
AC005015-1|AAF03524.1| 1046|Homo sapiens KIAA0291; similar roden...    30   8.9  
AB006629-1|BAA22960.2| 1024|Homo sapiens KIAA0291 protein.             30   8.9  

>X74331-1|CAA52378.1|  509|Homo sapiens DNA primase (p58 subunit)
           protein.
          Length = 509

 Score = 90.6 bits (215), Expect = 5e-18
 Identities = 54/139 (38%), Positives = 77/139 (55%), Gaps = 3/139 (2%)
 Frame = +1

Query: 256 GYAYIPHRDFISVLAAQYRTHLKQNLAKACHHLCEIEQDERLVCLLKGLHQSYSGNDYSE 435
           G+AY+P +D ++++  ++R  L + LA     L  ++ DERL  LL  L  SY+G DYS 
Sbjct: 205 GFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHLSHSYTGQDYST 264

Query: 436 TKAV--IPIESLDSISTKSFPLCMRQLMNN*ELPIT*NMGAGYSMGLFLKGIGVTLEDS* 609
              V  I ++ +D +STKSFP CMRQL            G     GLFLKGIG+TLE + 
Sbjct: 265 QGNVGKISLDQIDLLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQAL 324

Query: 610 GFGGKNSLR-LWIWDKFEK 663
            F  +  ++     DKF+K
Sbjct: 325 QFWKQEFIKGKMDPDKFDK 343



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 23/42 (54%), Positives = 30/42 (71%)
 Frame = +3

Query: 510 HEQLRIAHHLKHGGRLQYGLVLKRYWCDTGRLLRFWREEFIK 635
           H+ LR  HHL+HGGR+QYGL LK       + L+FW++EFIK
Sbjct: 292 HKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIK 333



 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 27/83 (32%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
 Frame = +2

Query: 11  FIARELELFKMRFAVMRGERLEVFFKLNNLCYTTISEDEKNEVIQNLIESTPY---SKID 181
           FI +E++L + RF+++  ++++ F K + L +  IS++EK    Q ++ S+P     K+ 
Sbjct: 120 FIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLG 179

Query: 182 NMKFYKVKFFEVLDLVKARKVFL 250
               YK+ F + LDL + RKV+L
Sbjct: 180 FESIYKIPFADALDLFRGRKVYL 202


>BC064931-1|AAH64931.1|  509|Homo sapiens primase, DNA, polypeptide
           2 (58kDa) protein.
          Length = 509

 Score = 90.6 bits (215), Expect = 5e-18
 Identities = 54/139 (38%), Positives = 77/139 (55%), Gaps = 3/139 (2%)
 Frame = +1

Query: 256 GYAYIPHRDFISVLAAQYRTHLKQNLAKACHHLCEIEQDERLVCLLKGLHQSYSGNDYSE 435
           G+AY+P +D ++++  ++R  L + LA     L  ++ DERL  LL  L  SY+G DYS 
Sbjct: 205 GFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHLSHSYTGQDYST 264

Query: 436 TKAV--IPIESLDSISTKSFPLCMRQLMNN*ELPIT*NMGAGYSMGLFLKGIGVTLEDS* 609
              V  I ++ +D +STKSFP CMRQL            G     GLFLKGIG+TLE + 
Sbjct: 265 QGNVGKISLDQIDLLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQAL 324

Query: 610 GFGGKNSLR-LWIWDKFEK 663
            F  +  ++     DKF+K
Sbjct: 325 QFWKQEFIKGKMDPDKFDK 343



 Score = 55.2 bits (127), Expect = 2e-07
 Identities = 23/42 (54%), Positives = 30/42 (71%)
 Frame = +3

Query: 510 HEQLRIAHHLKHGGRLQYGLVLKRYWCDTGRLLRFWREEFIK 635
           H+ LR  HHL+HGGR+QYGL LK       + L+FW++EFIK
Sbjct: 292 HKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIK 333



 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 27/83 (32%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
 Frame = +2

Query: 11  FIARELELFKMRFAVMRGERLEVFFKLNNLCYTTISEDEKNEVIQNLIESTPY---SKID 181
           FI +E++L + RF+++  ++++ F K + L +  IS++EK    Q ++ S+P     K+ 
Sbjct: 120 FIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLG 179

Query: 182 NMKFYKVKFFEVLDLVKARKVFL 250
               YK+ F + LDL + RKV+L
Sbjct: 180 FESIYKIPFADALDLFRGRKVYL 202


>AL162579-2|CAI40673.1|  340|Homo sapiens primase, polypeptide 2A,
           58kDa protein.
          Length = 340

 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 46/119 (38%), Positives = 65/119 (54%), Gaps = 2/119 (1%)
 Frame = +1

Query: 256 GYAYIPHRDFISVLAAQYRTHLKQNLAKACHHLCEIEQDERLVCLLKGLHQSYSGNDYSE 435
           G+AY+P +D ++++  ++R  L + LA     L  ++ DERL  LL  L  SY+  DYS 
Sbjct: 205 GFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHLSHSYTSQDYST 264

Query: 436 TKAV--IPIESLDSISTKSFPLCMRQLMNN*ELPIT*NMGAGYSMGLFLKGIGVTLEDS 606
              V  I ++ +D +STKSFPL M QL            G      LFLKGIG+TLE +
Sbjct: 265 QGNVGKISLDQIDLLSTKSFPLYMHQLHKALRENHHLCHGGRMQYVLFLKGIGLTLEQT 323



 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 27/83 (32%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
 Frame = +2

Query: 11  FIARELELFKMRFAVMRGERLEVFFKLNNLCYTTISEDEKNEVIQNLIESTPY---SKID 181
           FI +E++L + RF+++  ++++ F K + L +  IS++EK    Q ++ S+P     K+ 
Sbjct: 120 FIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLG 179

Query: 182 NMKFYKVKFFEVLDLVKARKVFL 250
               YK+ F + LDL + RKV+L
Sbjct: 180 FESIYKIPFADALDLFRGRKVYL 202



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +3

Query: 510 HEQLRIAHHLKHGGRLQYGLVLKRYWCDTGRLLRFWREEFIK 635
           H+ LR  HHL HGGR+QY L LK       + L+FW++EFIK
Sbjct: 292 HKALRENHHLCHGGRMQYVLFLKGIGLTLEQTLQFWKQEFIK 333


>AL121975-2|CAI42767.1|  340|Homo sapiens primase, polypeptide 2A,
           58kDa protein.
          Length = 340

 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 46/119 (38%), Positives = 65/119 (54%), Gaps = 2/119 (1%)
 Frame = +1

Query: 256 GYAYIPHRDFISVLAAQYRTHLKQNLAKACHHLCEIEQDERLVCLLKGLHQSYSGNDYSE 435
           G+AY+P +D ++++  ++R  L + LA     L  ++ DERL  LL  L  SY+  DYS 
Sbjct: 205 GFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHLSHSYTSQDYST 264

Query: 436 TKAV--IPIESLDSISTKSFPLCMRQLMNN*ELPIT*NMGAGYSMGLFLKGIGVTLEDS 606
              V  I ++ +D +STKSFPL M QL            G      LFLKGIG+TLE +
Sbjct: 265 QGNVGKISLDQIDLLSTKSFPLYMHQLHKALRENHHLCHGGRMQYVLFLKGIGLTLEQT 323



 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 27/83 (32%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
 Frame = +2

Query: 11  FIARELELFKMRFAVMRGERLEVFFKLNNLCYTTISEDEKNEVIQNLIESTPY---SKID 181
           FI +E++L + RF+++  ++++ F K + L +  IS++EK    Q ++ S+P     K+ 
Sbjct: 120 FIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLG 179

Query: 182 NMKFYKVKFFEVLDLVKARKVFL 250
               YK+ F + LDL + RKV+L
Sbjct: 180 FESIYKIPFADALDLFRGRKVYL 202



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +3

Query: 510 HEQLRIAHHLKHGGRLQYGLVLKRYWCDTGRLLRFWREEFIK 635
           H+ LR  HHL HGGR+QY L LK       + L+FW++EFIK
Sbjct: 292 HKALRENHHLCHGGRMQYVLFLKGIGLTLEQTLQFWKQEFIK 333


>AL121958-1|CAC03545.2|  340|Homo sapiens primase, polypeptide 2A,
           58kDa protein.
          Length = 340

 Score = 79.0 bits (186), Expect = 1e-14
 Identities = 46/119 (38%), Positives = 65/119 (54%), Gaps = 2/119 (1%)
 Frame = +1

Query: 256 GYAYIPHRDFISVLAAQYRTHLKQNLAKACHHLCEIEQDERLVCLLKGLHQSYSGNDYSE 435
           G+AY+P +D ++++  ++R  L + LA     L  ++ DERL  LL  L  SY+  DYS 
Sbjct: 205 GFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHLSHSYTSQDYST 264

Query: 436 TKAV--IPIESLDSISTKSFPLCMRQLMNN*ELPIT*NMGAGYSMGLFLKGIGVTLEDS 606
              V  I ++ +D +STKSFPL M QL            G      LFLKGIG+TLE +
Sbjct: 265 QGNVGKISLDQIDLLSTKSFPLYMHQLHKALRENHHLCHGGRMQYVLFLKGIGLTLEQT 323



 Score = 54.8 bits (126), Expect = 3e-07
 Identities = 27/83 (32%), Positives = 50/83 (60%), Gaps = 3/83 (3%)
 Frame = +2

Query: 11  FIARELELFKMRFAVMRGERLEVFFKLNNLCYTTISEDEKNEVIQNLIESTPY---SKID 181
           FI +E++L + RF+++  ++++ F K + L +  IS++EK    Q ++ S+P     K+ 
Sbjct: 120 FIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLG 179

Query: 182 NMKFYKVKFFEVLDLVKARKVFL 250
               YK+ F + LDL + RKV+L
Sbjct: 180 FESIYKIPFADALDLFRGRKVYL 202



 Score = 49.6 bits (113), Expect = 1e-05
 Identities = 22/42 (52%), Positives = 28/42 (66%)
 Frame = +3

Query: 510 HEQLRIAHHLKHGGRLQYGLVLKRYWCDTGRLLRFWREEFIK 635
           H+ LR  HHL HGGR+QY L LK       + L+FW++EFIK
Sbjct: 292 HKALRENHHLCHGGRMQYVLFLKGIGLTLEQTLQFWKQEFIK 333


>BC150332-1|AAI50333.1| 1011|Homo sapiens CAP-GLY domain containing
           linker protein 2 protein.
          Length = 1011

 Score = 29.9 bits (64), Expect = 8.9
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = +1

Query: 322 KQNLAKACHHLCEIEQDERLVCLLKGLHQSY 414
           +  +AKA  H+CE+E++   + LLK  H+ Y
Sbjct: 379 RAEVAKATSHICEVEKE---IALLKAQHEQY 406


>AF041059-1|AAB96784.1|  419|Homo sapiens similar to KIAA0291: DDBJ
           Accession Number AB006629, restin and CLIP-170 protein.
          Length = 419

 Score = 29.9 bits (64), Expect = 8.9
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = +1

Query: 322 KQNLAKACHHLCEIEQDERLVCLLKGLHQSY 414
           +  +AKA  H+CE+E++   + LLK  H+ Y
Sbjct: 338 RAEVAKATSHICEVEKE---IALLKAQHEQY 365


>AC005015-1|AAF03524.1| 1046|Homo sapiens KIAA0291; similar rodent
           cytoplasmic linker protein CLIP-115 and restin protein.
          Length = 1046

 Score = 29.9 bits (64), Expect = 8.9
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = +1

Query: 322 KQNLAKACHHLCEIEQDERLVCLLKGLHQSY 414
           +  +AKA  H+CE+E++   + LLK  H+ Y
Sbjct: 379 RAEVAKATSHICEVEKE---IALLKAQHEQY 406


>AB006629-1|BAA22960.2| 1024|Homo sapiens KIAA0291 protein.
          Length = 1024

 Score = 29.9 bits (64), Expect = 8.9
 Identities = 12/31 (38%), Positives = 20/31 (64%)
 Frame = +1

Query: 322 KQNLAKACHHLCEIEQDERLVCLLKGLHQSY 414
           +  +AKA  H+CE+E++   + LLK  H+ Y
Sbjct: 392 RAEVAKATSHICEVEKE---IALLKAQHEQY 419


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,432,949
Number of Sequences: 237096
Number of extensions: 1880682
Number of successful extensions: 3338
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 3208
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3323
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7895240574
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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