Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= pg--0917.Seq
(695 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 102 1e-21
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 102 1e-21
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 102 1e-21
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 102 1e-21
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 100 4e-21
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 100 4e-21
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 100 4e-21
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 100 4e-21
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 100 4e-21
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 100 4e-21
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 92 2e-18
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 90 8e-18
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 90 8e-18
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 90 8e-18
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 90 8e-18
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 90 8e-18
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 89 1e-17
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 89 1e-17
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 89 1e-17
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 55 2e-07
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 55 2e-07
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 55 2e-07
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 43 0.001
BC111769-1|AAI11770.1| 177|Homo sapiens FLJ40448 protein protein. 33 1.3
AK097767-1|BAC05165.1| 185|Homo sapiens protein ( Homo sapiens ... 33 1.3
AM079743-1|CAL03889.1| 101|Homo sapiens immunoglobulin heavy ch... 30 9.1
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 102 bits (245), Expect = 1e-21
Identities = 44/84 (52%), Positives = 58/84 (69%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
D+ACDSY+Q + D+ M L + YRFSISW R+ P G + I+S G YY+ LINGL+
Sbjct: 950 DIACDSYHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVA 1009
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
I PMVTL+H D+P+ QD+GGW
Sbjct: 1010 SNIFPMVTLFHWDLPQALQDIGGW 1033
Score = 96.7 bits (230), Expect = 7e-20
Identities = 42/84 (50%), Positives = 56/84 (66%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVACDSY++ +D+ + LG+ YRFSISW R+LP G I+ G YY LI+ LL
Sbjct: 1423 DVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLA 1482
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
I+P VT+YH D+P+ QD+GGW
Sbjct: 1483 ASIQPQVTIYHWDLPQTLQDVGGW 1506
Score = 86.6 bits (205), Expect = 7e-17
Identities = 40/90 (44%), Positives = 54/90 (60%)
Frame = -2
Query: 526 QGSLQRDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNL 347
+G +VA DSY++ D+ + L Y+FSISW R+ P G + S G YY+ L
Sbjct: 421 EGQATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKL 480
Query: 346 INGLLDRGIEPMVTLYHSDMPKIFQDLGGW 257
I+ L D GIEPM TL+H D+P+ QD GGW
Sbjct: 481 IDRLQDAGIEPMATLFHWDLPQALQDHGGW 510
Score = 55.2 bits (127), Expect = 2e-07
Identities = 20/43 (46%), Positives = 31/43 (72%)
Frame = -3
Query: 636 FKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
F +G ++S+YQIEG+W+ K PS WD++THT +KD++ G
Sbjct: 907 FLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATG 949
Score = 51.2 bits (117), Expect = 3e-06
Identities = 25/64 (39%), Positives = 34/64 (53%), Gaps = 4/64 (6%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEPLHAC----DSSSRVLGVVEPFLAPYLCT 87
NP + + F YAD F +GDRVK W+T NEP++ S GV +P APY
Sbjct: 1035 NPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDPGWAPYRIA 1094
Query: 86 KTLL 75
T++
Sbjct: 1095 HTVI 1098
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEP----LHACDSSSRVLGVVEPFLAPYLCT 87
N + + F DYA FS +GDRVKLW+T +EP + G+ +P +A +
Sbjct: 512 NESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPGISDPGVASFKVA 571
Query: 86 KTLLXXXXXXXXXXXXXXKPMYQGKVGI 3
+L +P QG VGI
Sbjct: 572 HLVLKAHARTWHHYNSHHRPQQQGHVGI 599
Score = 46.8 bits (106), Expect = 7e-05
Identities = 20/47 (42%), Positives = 31/47 (65%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AA+++YQIEG+W K S WD ++HT P R+++ + G
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIG 1422
Score = 43.2 bits (97), Expect = 0.001
Identities = 17/32 (53%), Positives = 22/32 (68%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
N + + F +YADV F GD+VK WIT+NEP
Sbjct: 1508 NETIVQRFKEYADVLFQRLGDKVKFWITLNEP 1539
Score = 37.5 bits (83), Expect = 0.045
Identities = 17/51 (33%), Positives = 25/51 (49%)
Frame = -2
Query: 436 YRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLDRGIEPMVTLYHSDMP 284
Y+ +SW +LLP G Q Y L+ L ++PMV L+H +P
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLP 137
Score = 33.9 bits (74), Expect = 0.56
Identities = 12/31 (38%), Positives = 18/31 (58%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWD 556
FP F +GA+T ++ +EG W + S WD
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWD 412
Score = 33.1 bits (72), Expect = 0.97
Identities = 13/27 (48%), Positives = 18/27 (66%)
Frame = -1
Query: 242 AEWFADYADVAFSLYGDRVKLWITINE 162
A+ FADYA AF +GD V +W T ++
Sbjct: 148 ADLFADYATFAFHSFGDLVGIWFTFSD 174
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 102 bits (245), Expect = 1e-21
Identities = 44/84 (52%), Positives = 58/84 (69%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
D+ACDSY+Q + D+ M L + YRFSISW R+ P G + I+S G YY+ LINGL+
Sbjct: 950 DIACDSYHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVA 1009
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
I PMVTL+H D+P+ QD+GGW
Sbjct: 1010 SNIFPMVTLFHWDLPQALQDIGGW 1033
Score = 96.7 bits (230), Expect = 7e-20
Identities = 42/84 (50%), Positives = 56/84 (66%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVACDSY++ +D+ + LG+ YRFSISW R+LP G I+ G YY LI+ LL
Sbjct: 1423 DVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLA 1482
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
I+P VT+YH D+P+ QD+GGW
Sbjct: 1483 ASIQPQVTIYHWDLPQTLQDVGGW 1506
Score = 86.6 bits (205), Expect = 7e-17
Identities = 40/90 (44%), Positives = 54/90 (60%)
Frame = -2
Query: 526 QGSLQRDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNL 347
+G +VA DSY++ D+ + L Y+FSISW R+ P G + S G YY+ L
Sbjct: 421 EGQATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKL 480
Query: 346 INGLLDRGIEPMVTLYHSDMPKIFQDLGGW 257
I+ L D GIEPM TL+H D+P+ QD GGW
Sbjct: 481 IDRLQDAGIEPMATLFHWDLPQALQDHGGW 510
Score = 55.2 bits (127), Expect = 2e-07
Identities = 20/43 (46%), Positives = 31/43 (72%)
Frame = -3
Query: 636 FKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
F +G ++S+YQIEG+W+ K PS WD++THT +KD++ G
Sbjct: 907 FLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATG 949
Score = 49.6 bits (113), Expect = 1e-05
Identities = 24/57 (42%), Positives = 31/57 (54%), Gaps = 4/57 (7%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEPLHAC----DSSSRVLGVVEPFLAPY 96
NP + + F YAD F +GDRVK W+T NEP++ S GV +P APY
Sbjct: 1035 NPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDPGWAPY 1091
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEP----LHACDSSSRVLGVVEPFLAPYLCT 87
N + + F DYA FS +GDRVKLW+T +EP + G+ +P +A +
Sbjct: 512 NESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPGISDPGVASFKVA 571
Query: 86 KTLLXXXXXXXXXXXXXXKPMYQGKVGI 3
+L +P QG VGI
Sbjct: 572 HLVLKAHARTWHHYNSHHRPQQQGHVGI 599
Score = 46.8 bits (106), Expect = 7e-05
Identities = 20/47 (42%), Positives = 31/47 (65%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AA+++YQIEG+W K S WD ++HT P R+++ + G
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIG 1422
Score = 43.2 bits (97), Expect = 0.001
Identities = 17/32 (53%), Positives = 22/32 (68%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
N + + F +YADV F GD+VK WIT+NEP
Sbjct: 1508 NETIVQRFKEYADVLFQRLGDKVKFWITLNEP 1539
Score = 37.5 bits (83), Expect = 0.045
Identities = 17/51 (33%), Positives = 25/51 (49%)
Frame = -2
Query: 436 YRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLDRGIEPMVTLYHSDMP 284
Y+ +SW +LLP G Q Y L+ L ++PMV L+H +P
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLP 137
Score = 33.9 bits (74), Expect = 0.56
Identities = 12/31 (38%), Positives = 18/31 (58%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWD 556
FP F +GA+T ++ +EG W + S WD
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWD 412
Score = 33.1 bits (72), Expect = 0.97
Identities = 13/27 (48%), Positives = 18/27 (66%)
Frame = -1
Query: 242 AEWFADYADVAFSLYGDRVKLWITINE 162
A+ FADYA AF +GD V +W T ++
Sbjct: 148 ADLFADYATFAFHSFGDLVGIWFTFSD 174
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 102 bits (245), Expect = 1e-21
Identities = 44/84 (52%), Positives = 58/84 (69%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
D+ACDSY+Q + D+ M L + YRFSISW R+ P G + I+S G YY+ LINGL+
Sbjct: 382 DIACDSYHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVA 441
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
I PMVTL+H D+P+ QD+GGW
Sbjct: 442 SNIFPMVTLFHWDLPQALQDIGGW 465
Score = 96.7 bits (230), Expect = 7e-20
Identities = 42/84 (50%), Positives = 56/84 (66%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVACDSY++ +D+ + LG+ YRFSISW R+LP G I+ G YY LI+ LL
Sbjct: 855 DVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLA 914
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
I+P VT+YH D+P+ QD+GGW
Sbjct: 915 ASIQPQVTIYHWDLPQTLQDVGGW 938
Score = 55.2 bits (127), Expect = 2e-07
Identities = 20/43 (46%), Positives = 31/43 (72%)
Frame = -3
Query: 636 FKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
F +G ++S+YQIEG+W+ K PS WD++THT +KD++ G
Sbjct: 339 FLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATG 381
Score = 51.2 bits (117), Expect = 3e-06
Identities = 25/64 (39%), Positives = 34/64 (53%), Gaps = 4/64 (6%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEPLHAC----DSSSRVLGVVEPFLAPYLCT 87
NP + + F YAD F +GDRVK W+T NEP++ S GV +P APY
Sbjct: 467 NPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDPGWAPYRIA 526
Query: 86 KTLL 75
T++
Sbjct: 527 HTVI 530
Score = 46.8 bits (106), Expect = 7e-05
Identities = 20/47 (42%), Positives = 31/47 (65%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AA+++YQIEG+W K S WD ++HT P R+++ + G
Sbjct: 809 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIG 854
Score = 43.2 bits (97), Expect = 0.001
Identities = 17/32 (53%), Positives = 22/32 (68%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
N + + F +YADV F GD+VK WIT+NEP
Sbjct: 940 NETIVQRFKEYADVLFQRLGDKVKFWITLNEP 971
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 102 bits (245), Expect = 1e-21
Identities = 44/84 (52%), Positives = 58/84 (69%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
D+ACDSY+Q + D+ M L + YRFSISW R+ P G + I+S G YY+ LINGL+
Sbjct: 950 DIACDSYHQLDADLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVA 1009
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
I PMVTL+H D+P+ QD+GGW
Sbjct: 1010 SNIFPMVTLFHWDLPQALQDIGGW 1033
Score = 96.7 bits (230), Expect = 7e-20
Identities = 42/84 (50%), Positives = 56/84 (66%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVACDSY++ +D+ + LG+ YRFSISW R+LP G I+ G YY LI+ LL
Sbjct: 1423 DVACDSYHKIAEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLA 1482
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
I+P VT+YH D+P+ QD+GGW
Sbjct: 1483 ASIQPQVTIYHWDLPQTLQDVGGW 1506
Score = 86.6 bits (205), Expect = 7e-17
Identities = 40/90 (44%), Positives = 54/90 (60%)
Frame = -2
Query: 526 QGSLQRDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNL 347
+G +VA DSY++ D+ + L Y+FSISW R+ P G + S G YY+ L
Sbjct: 421 EGQATLEVASDSYHKVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKL 480
Query: 346 INGLLDRGIEPMVTLYHSDMPKIFQDLGGW 257
I+ L D GIEPM TL+H D+P+ QD GGW
Sbjct: 481 IDRLQDAGIEPMATLFHWDLPQALQDHGGW 510
Score = 55.2 bits (127), Expect = 2e-07
Identities = 20/43 (46%), Positives = 31/43 (72%)
Frame = -3
Query: 636 FKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
F +G ++S+YQIEG+W+ K PS WD++THT +KD++ G
Sbjct: 907 FLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATG 949
Score = 49.6 bits (113), Expect = 1e-05
Identities = 24/57 (42%), Positives = 31/57 (54%), Gaps = 4/57 (7%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEPLHAC----DSSSRVLGVVEPFLAPY 96
NP + + F YAD F +GDRVK W+T NEP++ S GV +P APY
Sbjct: 1035 NPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDPGWAPY 1091
Score = 46.8 bits (106), Expect = 7e-05
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 4/88 (4%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEP----LHACDSSSRVLGVVEPFLAPYLCT 87
N + + F DYA FS +GDRVKLW+T +EP + G+ +P +A +
Sbjct: 512 NESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPGISDPGVASFKVA 571
Query: 86 KTLLXXXXXXXXXXXXXXKPMYQGKVGI 3
+L +P QG VGI
Sbjct: 572 HLVLKAHARTWHHYNSHHRPQQQGHVGI 599
Score = 46.8 bits (106), Expect = 7e-05
Identities = 20/47 (42%), Positives = 31/47 (65%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AA+++YQIEG+W K S WD ++HT P R+++ + G
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIG 1422
Score = 43.2 bits (97), Expect = 0.001
Identities = 17/32 (53%), Positives = 22/32 (68%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
N + + F +YADV F GD+VK WIT+NEP
Sbjct: 1508 NETIVQRFKEYADVLFQRLGDKVKFWITLNEP 1539
Score = 37.5 bits (83), Expect = 0.045
Identities = 17/51 (33%), Positives = 25/51 (49%)
Frame = -2
Query: 436 YRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLDRGIEPMVTLYHSDMP 284
Y+ +SW +LLP G Q Y L+ L ++PMV L+H +P
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLP 137
Score = 33.9 bits (74), Expect = 0.56
Identities = 12/31 (38%), Positives = 18/31 (58%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWD 556
FP F +GA+T ++ +EG W + S WD
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWD 412
Score = 33.1 bits (72), Expect = 0.97
Identities = 13/27 (48%), Positives = 18/27 (66%)
Frame = -1
Query: 242 AEWFADYADVAFSLYGDRVKLWITINE 162
A+ FADYA AF +GD V +W T ++
Sbjct: 148 ADLFADYATFAFHSFGDLVGIWFTFSD 174
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 100 bits (240), Expect = 4e-21
Identities = 43/84 (51%), Positives = 58/84 (69%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVAC SY +E+D++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL
Sbjct: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLK 109
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
G+ P+VTLYH D+P+ +D GGW
Sbjct: 110 NGVTPIVTLYHFDLPQTLEDQGGW 133
Score = 50.0 bits (114), Expect = 8e-06
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AAT++YQ+EG W+ K P WD +TH R+ + G
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTG 49
Score = 38.7 bits (86), Expect = 0.020
Identities = 17/26 (65%), Positives = 18/26 (69%)
Frame = -1
Query: 239 EWFADYADVAFSLYGDRVKLWITINE 162
E F YA FS +GDRVK WITINE
Sbjct: 140 ESFDKYAQFCFSTFGDRVKQWITINE 165
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 100 bits (240), Expect = 4e-21
Identities = 43/84 (51%), Positives = 58/84 (69%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVAC SY +E+D++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL
Sbjct: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLK 109
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
G+ P+VTLYH D+P+ +D GGW
Sbjct: 110 NGVTPIVTLYHFDLPQTLEDQGGW 133
Score = 50.0 bits (114), Expect = 8e-06
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AAT++YQ+EG W+ K P WD +TH R+ + G
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTG 49
Score = 38.7 bits (86), Expect = 0.020
Identities = 17/26 (65%), Positives = 18/26 (69%)
Frame = -1
Query: 239 EWFADYADVAFSLYGDRVKLWITINE 162
E F YA FS +GDRVK WITINE
Sbjct: 140 ESFDKYAQFCFSTFGDRVKQWITINE 165
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 100 bits (240), Expect = 4e-21
Identities = 43/84 (51%), Positives = 58/84 (69%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVAC SY +E+D++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL
Sbjct: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLK 109
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
G+ P+VTLYH D+P+ +D GGW
Sbjct: 110 NGVTPIVTLYHFDLPQTLEDQGGW 133
Score = 50.0 bits (114), Expect = 8e-06
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AAT++YQ+EG W+ K P WD +TH R+ + G
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTG 49
Score = 38.7 bits (86), Expect = 0.020
Identities = 17/26 (65%), Positives = 18/26 (69%)
Frame = -1
Query: 239 EWFADYADVAFSLYGDRVKLWITINE 162
E F YA FS +GDRVK WITINE
Sbjct: 140 ESFDKYAQFCFSTFGDRVKQWITINE 165
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 100 bits (240), Expect = 4e-21
Identities = 43/84 (51%), Positives = 58/84 (69%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVAC SY +E+D++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL
Sbjct: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLK 109
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
G+ P+VTLYH D+P+ +D GGW
Sbjct: 110 NGVTPIVTLYHFDLPQTLEDQGGW 133
Score = 50.0 bits (114), Expect = 8e-06
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AAT++YQ+EG W+ K P WD +TH R+ + G
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTG 49
Score = 38.7 bits (86), Expect = 0.020
Identities = 17/26 (65%), Positives = 18/26 (69%)
Frame = -1
Query: 239 EWFADYADVAFSLYGDRVKLWITINE 162
E F YA FS +GDRVK WITINE
Sbjct: 140 ESFDKYAQFCFSTFGDRVKQWITINE 165
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 100 bits (240), Expect = 4e-21
Identities = 43/84 (51%), Positives = 58/84 (69%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVAC SY +E+D++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL
Sbjct: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLK 109
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
G+ P+VTLYH D+P+ +D GGW
Sbjct: 110 NGVTPIVTLYHFDLPQTLEDQGGW 133
Score = 50.0 bits (114), Expect = 8e-06
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AAT++YQ+EG W+ K P WD +TH R+ + G
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTG 49
Score = 38.7 bits (86), Expect = 0.020
Identities = 17/26 (65%), Positives = 18/26 (69%)
Frame = -1
Query: 239 EWFADYADVAFSLYGDRVKLWITINE 162
E F YA FS +GDRVK WITINE
Sbjct: 140 ESFDKYAQFCFSTFGDRVKQWITINE 165
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 100 bits (240), Expect = 4e-21
Identities = 43/84 (51%), Positives = 58/84 (69%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVAC SY +E+D++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL
Sbjct: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLK 109
Query: 328 RGIEPMVTLYHSDMPKIFQDLGGW 257
G+ P+VTLYH D+P+ +D GGW
Sbjct: 110 NGVTPIVTLYHFDLPQTLEDQGGW 133
Score = 50.0 bits (114), Expect = 8e-06
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AAT++YQ+EG W+ K P WD +TH R+ + G
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTG 49
Score = 38.7 bits (86), Expect = 0.020
Identities = 17/26 (65%), Positives = 18/26 (69%)
Frame = -1
Query: 239 EWFADYADVAFSLYGDRVKLWITINE 162
E F YA FS +GDRVK WITINE
Sbjct: 140 ESFDKYAQFCFSTFGDRVKQWITINE 165
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 91.9 bits (218), Expect = 2e-18
Identities = 42/98 (42%), Positives = 64/98 (65%), Gaps = 2/98 (2%)
Frame = -2
Query: 523 GSLQRDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRT-RISSDGRQYYDNL 347
G+ DVACD Y + ++DI + +L ++ YRFS+SWPRLLP G R +++ G ++Y +L
Sbjct: 79 GNETADVACDGYYKVQEDIILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDL 138
Query: 346 INGLLDRGIEPMVTLYHSDMPKIFQ-DLGGWAILKWQN 236
I+ LL I P+VTL+H D+P++ Q GGW + N
Sbjct: 139 IDALLSSNITPIVTLHHWDLPQLLQVKYGGWQNVSMAN 176
Score = 46.4 bits (105), Expect = 1e-04
Identities = 18/38 (47%), Positives = 26/38 (68%)
Frame = -1
Query: 272 RFGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
++G N MA +F DYA++ F +GDRVK WIT ++P
Sbjct: 165 KYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDP 202
Score = 46.0 bits (104), Expect = 1e-04
Identities = 17/36 (47%), Positives = 24/36 (66%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHT 541
FP F +G +S+YQ EG+W+ K PS WD +TH+
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHS 72
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/86 (48%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVA DSYN +D E +LG+ YRFSISW R+LP G + +G +YY L+ L +
Sbjct: 123 DVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRE 182
Query: 328 RGIEPMVTLYHSDMPKIFQD-LGGWA 254
G++P+VTLYH D+P+ QD GGWA
Sbjct: 183 LGVQPVVTLYHWDLPQRLQDAYGGWA 208
Score = 40.3 bits (90), Expect = 0.006
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = -1
Query: 269 FGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
+G N +A+ F DYA++ F +G +VK WITI+ P
Sbjct: 204 YGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Score = 37.5 bits (83), Expect = 0.045
Identities = 14/35 (40%), Positives = 19/35 (54%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTH 544
FP F + +++YQ EG W K S WD +TH
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTH 95
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/86 (48%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVA DSYN +D E +LG+ YRFSISW R+LP G + +G +YY L+ L +
Sbjct: 123 DVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRE 182
Query: 328 RGIEPMVTLYHSDMPKIFQD-LGGWA 254
G++P+VTLYH D+P+ QD GGWA
Sbjct: 183 LGVQPVVTLYHWDLPQRLQDAYGGWA 208
Score = 42.7 bits (96), Expect = 0.001
Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Frame = -2
Query: 514 QRDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGL 335
+R C + + I + +++ + +RFS+ W +LP G +++++ QYY + + L
Sbjct: 567 KRKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASEL 626
Query: 334 LDRGIEPMVTLY-----HSDMPKIFQDLGGW 257
+ I P+V L+ + +P++ G W
Sbjct: 627 VRVNITPVVALWQPMAPNQGLPRLLARQGAW 657
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = -1
Query: 278 ISRFGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
++R G NP A FA+YA + F G VKLWIT+NEP
Sbjct: 651 LARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
Score = 40.3 bits (90), Expect = 0.006
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = -1
Query: 269 FGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
+G N +A+ F DYA++ F +G +VK WITI+ P
Sbjct: 204 YGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Score = 37.5 bits (83), Expect = 0.045
Identities = 14/35 (40%), Positives = 19/35 (54%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTH 544
FP F + +++YQ EG W K S WD +TH
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTH 95
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/86 (48%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVA DSYN +D E +LG+ YRFSISW R+LP G + +G +YY L+ L +
Sbjct: 123 DVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRE 182
Query: 328 RGIEPMVTLYHSDMPKIFQD-LGGWA 254
G++P+VTLYH D+P+ QD GGWA
Sbjct: 183 LGVQPVVTLYHWDLPQRLQDAYGGWA 208
Score = 40.3 bits (90), Expect = 0.006
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = -1
Query: 269 FGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
+G N +A+ F DYA++ F +G +VK WITI+ P
Sbjct: 204 YGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Score = 37.5 bits (83), Expect = 0.045
Identities = 14/35 (40%), Positives = 19/35 (54%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTH 544
FP F + +++YQ EG W K S WD +TH
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTH 95
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/86 (48%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVA DSYN +D E +LG+ YRFSISW R+LP G + +G +YY L+ L +
Sbjct: 123 DVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRE 182
Query: 328 RGIEPMVTLYHSDMPKIFQD-LGGWA 254
G++P+VTLYH D+P+ QD GGWA
Sbjct: 183 LGVQPVVTLYHWDLPQRLQDAYGGWA 208
Score = 42.7 bits (96), Expect = 0.001
Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Frame = -2
Query: 514 QRDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGL 335
+R C + + I + +++ + +RFS+ W +LP G +++++ QYY + + L
Sbjct: 567 KRKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASEL 626
Query: 334 LDRGIEPMVTLY-----HSDMPKIFQDLGGW 257
+ I P+V L+ + +P++ G W
Sbjct: 627 VRVNITPVVALWQPMAPNQGLPRLLARQGAW 657
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = -1
Query: 278 ISRFGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
++R G NP A FA+YA + F G VKLWIT+NEP
Sbjct: 651 LARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
Score = 40.3 bits (90), Expect = 0.006
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = -1
Query: 269 FGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
+G N +A+ F DYA++ F +G +VK WITI+ P
Sbjct: 204 YGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Score = 37.5 bits (83), Expect = 0.045
Identities = 14/35 (40%), Positives = 19/35 (54%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTH 544
FP F + +++YQ EG W K S WD +TH
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTH 95
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 89.8 bits (213), Expect = 8e-18
Identities = 42/86 (48%), Positives = 56/86 (65%), Gaps = 1/86 (1%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLD 329
DVA DSYN +D E +LG+ YRFSISW R+LP G + +G +YY L+ L +
Sbjct: 123 DVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRE 182
Query: 328 RGIEPMVTLYHSDMPKIFQD-LGGWA 254
G++P+VTLYH D+P+ QD GGWA
Sbjct: 183 LGVQPVVTLYHWDLPQRLQDAYGGWA 208
Score = 42.7 bits (96), Expect = 0.001
Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Frame = -2
Query: 514 QRDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGL 335
+R C + + I + +++ + +RFS+ W +LP G +++++ QYY + + L
Sbjct: 567 KRKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASEL 626
Query: 334 LDRGIEPMVTLY-----HSDMPKIFQDLGGW 257
+ I P+V L+ + +P++ G W
Sbjct: 627 VRVNITPVVALWQPMAPNQGLPRLLARQGAW 657
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = -1
Query: 278 ISRFGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
++R G NP A FA+YA + F G VKLWIT+NEP
Sbjct: 651 LARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
Score = 40.3 bits (90), Expect = 0.006
Identities = 16/37 (43%), Positives = 24/37 (64%)
Frame = -1
Query: 269 FGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
+G N +A+ F DYA++ F +G +VK WITI+ P
Sbjct: 204 YGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Score = 37.5 bits (83), Expect = 0.045
Identities = 14/35 (40%), Positives = 19/35 (54%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTH 544
FP F + +++YQ EG W K S WD +TH
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTH 95
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 89.4 bits (212), Expect = 1e-17
Identities = 41/81 (50%), Positives = 54/81 (66%), Gaps = 1/81 (1%)
Frame = -2
Query: 496 DSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLDRGIE 317
DSY EKD+ + +G+ FY+FSISWPRL P G T ++ G QYY L++ L+ R IE
Sbjct: 129 DSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIE 188
Query: 316 PMVTLYHSDMPKIFQD-LGGW 257
P+VTLYH D+P Q+ GGW
Sbjct: 189 PIVTLYHWDLPLALQEKYGGW 209
Score = 51.6 bits (118), Expect = 3e-06
Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Frame = -2
Query: 511 RDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLL 332
R C + +K +EM ++ + YRF++ W +LP G + ++ +YY +++ L
Sbjct: 572 RPAQCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGL 631
Query: 331 DRGIEPMVTLY-----HSDMPKIFQDLGGW 257
GI MVTLY H +P+ GW
Sbjct: 632 KLGISAMVTLYYPTHAHLGLPEPLLHADGW 661
Score = 45.2 bits (102), Expect = 2e-04
Identities = 22/41 (53%), Positives = 24/41 (58%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEPLHACDSSSR 132
NP AE F YA + F GD VKLWITINEP D +R
Sbjct: 663 NPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDIYNR 703
Score = 44.8 bits (101), Expect = 3e-04
Identities = 19/47 (40%), Positives = 26/47 (55%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP+ F +G T + Q+EGSW K PS WD + HT + +NG
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG 126
Score = 42.3 bits (95), Expect = 0.002
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = -1
Query: 272 RFGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
++G N + + F DYA F ++GDRVK WITI+ P
Sbjct: 205 KYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNP 242
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 89.4 bits (212), Expect = 1e-17
Identities = 41/81 (50%), Positives = 54/81 (66%), Gaps = 1/81 (1%)
Frame = -2
Query: 496 DSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLDRGIE 317
DSY EKD+ + +G+ FY+FSISWPRL P G T ++ G QYY L++ L+ R IE
Sbjct: 129 DSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIE 188
Query: 316 PMVTLYHSDMPKIFQD-LGGW 257
P+VTLYH D+P Q+ GGW
Sbjct: 189 PIVTLYHWDLPLALQEKYGGW 209
Score = 51.6 bits (118), Expect = 3e-06
Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Frame = -2
Query: 511 RDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLL 332
R C + +K +EM ++ + YRF++ W +LP G + ++ +YY +++ L
Sbjct: 572 RPAQCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGL 631
Query: 331 DRGIEPMVTLY-----HSDMPKIFQDLGGW 257
GI MVTLY H +P+ GW
Sbjct: 632 KLGISAMVTLYYPTHAHLGLPEPLLHADGW 661
Score = 45.2 bits (102), Expect = 2e-04
Identities = 22/41 (53%), Positives = 24/41 (58%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEPLHACDSSSR 132
NP AE F YA + F GD VKLWITINEP D +R
Sbjct: 663 NPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDIYNR 703
Score = 44.8 bits (101), Expect = 3e-04
Identities = 19/47 (40%), Positives = 26/47 (55%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP+ F +G T + Q+EGSW K PS WD + HT + +NG
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG 126
Score = 42.3 bits (95), Expect = 0.002
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = -1
Query: 272 RFGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
++G N + + F DYA F ++GDRVK WITI+ P
Sbjct: 205 KYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNP 242
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 89.4 bits (212), Expect = 1e-17
Identities = 41/81 (50%), Positives = 54/81 (66%), Gaps = 1/81 (1%)
Frame = -2
Query: 496 DSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLLDRGIE 317
DSY EKD+ + +G+ FY+FSISWPRL P G T ++ G QYY L++ L+ R IE
Sbjct: 129 DSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIE 188
Query: 316 PMVTLYHSDMPKIFQD-LGGW 257
P+VTLYH D+P Q+ GGW
Sbjct: 189 PIVTLYHWDLPLALQEKYGGW 209
Score = 51.6 bits (118), Expect = 3e-06
Identities = 26/90 (28%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Frame = -2
Query: 511 RDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGLL 332
R C + +K +EM ++ + YRF++ W +LP G + ++ +YY +++ L
Sbjct: 572 RPAQCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGL 631
Query: 331 DRGIEPMVTLY-----HSDMPKIFQDLGGW 257
GI MVTLY H +P+ GW
Sbjct: 632 KLGISAMVTLYYPTHAHLGLPEPLLHADGW 661
Score = 45.2 bits (102), Expect = 2e-04
Identities = 22/41 (53%), Positives = 24/41 (58%)
Frame = -1
Query: 254 NPEMAEWFADYADVAFSLYGDRVKLWITINEPLHACDSSSR 132
NP AE F YA + F GD VKLWITINEP D +R
Sbjct: 663 NPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDIYNR 703
Score = 44.8 bits (101), Expect = 3e-04
Identities = 19/47 (40%), Positives = 26/47 (55%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP+ F +G T + Q+EGSW K PS WD + HT + +NG
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG 126
Score = 42.3 bits (95), Expect = 0.002
Identities = 17/38 (44%), Positives = 24/38 (63%)
Frame = -1
Query: 272 RFGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
++G N + + F DYA F ++GDRVK WITI+ P
Sbjct: 205 KYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNP 242
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 55.2 bits (127), Expect = 2e-07
Identities = 23/38 (60%), Positives = 29/38 (76%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKG 395
DVAC SY +E+D++ +QLGL YRFS+SW RLLP G
Sbjct: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDG 87
Score = 50.0 bits (114), Expect = 8e-06
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AAT++YQ+EG W+ K P WD +TH R+ + G
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTG 49
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 55.2 bits (127), Expect = 2e-07
Identities = 23/38 (60%), Positives = 29/38 (76%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKG 395
DVAC SY +E+D++ +QLGL YRFS+SW RLLP G
Sbjct: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDG 87
Score = 46.0 bits (104), Expect = 1e-04
Identities = 18/47 (38%), Positives = 26/47 (55%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AAT++YQ+EG W+ K WD +TH R+ + G
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTG 49
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 55.2 bits (127), Expect = 2e-07
Identities = 23/38 (60%), Positives = 29/38 (76%)
Frame = -2
Query: 508 DVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKG 395
DVAC SY +E+D++ +QLGL YRFS+SW RLLP G
Sbjct: 50 DVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDG 87
Score = 50.0 bits (114), Expect = 8e-06
Identities = 19/47 (40%), Positives = 27/47 (57%)
Frame = -3
Query: 648 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNG 508
FP F + AAT++YQ+EG W+ K P WD +TH R+ + G
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTG 49
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 42.7 bits (96), Expect = 0.001
Identities = 21/91 (23%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Frame = -2
Query: 514 QRDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISSDGRQYYDNLINGL 335
+R C + + I + +++ + +RFS+ W +LP G +++++ QYY + + L
Sbjct: 294 KRKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASEL 353
Query: 334 LDRGIEPMVTLY-----HSDMPKIFQDLGGW 257
+ I P+V L+ + +P++ G W
Sbjct: 354 VRVNITPVVALWQPMAPNQGLPRLLARQGAW 384
Score = 42.3 bits (95), Expect = 0.002
Identities = 20/40 (50%), Positives = 25/40 (62%)
Frame = -1
Query: 278 ISRFGRLGNPEMAEWFADYADVAFSLYGDRVKLWITINEP 159
++R G NP A FA+YA + F G VKLWIT+NEP
Sbjct: 378 LARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 417
>BC111769-1|AAI11770.1| 177|Homo sapiens FLJ40448 protein protein.
Length = 177
Score = 32.7 bits (71), Expect = 1.3
Identities = 11/25 (44%), Positives = 15/25 (60%)
Frame = -2
Query: 139 AHAFLGSSSHSWLHICARKLCCMLT 65
AH G + WLH+C+R+ C LT
Sbjct: 81 AHPVAGGTQEPWLHLCSRRTCGQLT 105
>AK097767-1|BAC05165.1| 185|Homo sapiens protein ( Homo sapiens
cDNA FLJ40448 fis, clone TESTI2040815. ).
Length = 185
Score = 32.7 bits (71), Expect = 1.3
Identities = 11/25 (44%), Positives = 15/25 (60%)
Frame = -2
Query: 139 AHAFLGSSSHSWLHICARKLCCMLT 65
AH G + WLH+C+R+ C LT
Sbjct: 81 AHPVAGGTQEPWLHLCSRRTCGQLT 105
>AM079743-1|CAL03889.1| 101|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 101
Score = 29.9 bits (64), Expect = 9.1
Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 4/41 (9%)
Frame = -2
Query: 448 GLDFYRFSISWPRLLP-KGFR--TRIS-SDGRQYYDNLING 338
G F F++SW R P KG + IS +DGR YY++ + G
Sbjct: 29 GFSFSTFAVSWVRQAPGKGLEWVSFISGADGRTYYEDSVKG 69
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,635,297
Number of Sequences: 237096
Number of extensions: 2470886
Number of successful extensions: 5406
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 5090
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5405
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8007229802
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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