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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= pg--0843.Seq
         (674 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

D21260-1|BAA04801.2| 1685|Homo sapiens KIAA0034 protein.              140   5e-33
BC054489-1|AAH54489.1| 1675|Homo sapiens clathrin, heavy chain (...   140   5e-33
BC051800-1|AAH51800.1| 1639|Homo sapiens CLTC protein protein.        140   5e-33
X95486-1|CAA64752.1| 1640|Homo sapiens clathrin heavy chain poly...   132   8e-31
U60803-1|AAB40909.1| 1569|Homo sapiens clathrin heavy chain 2 pr...   132   8e-31
U60802-1|AAB40908.1| 1626|Homo sapiens clathrin heavy chain 2 pr...   132   8e-31
U41763-1|AAC50494.1| 1640|Homo sapiens muscle clathrin heavy cha...   132   8e-31
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein.        30   8.6  
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g...    30   8.6  
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g...    30   8.6  
AC008178-1|AAY24266.1|  773|Homo sapiens unknown protein.              30   8.6  

>D21260-1|BAA04801.2| 1685|Homo sapiens KIAA0034 protein.
          Length = 1685

 Score =  140 bits (338), Expect = 5e-33
 Identities = 69/85 (81%), Positives = 75/85 (88%)
 Frame = +2

Query: 254 TDKFICVREKVGETAEVVIIDMADPTNPIRRPISADSAIMNPASKVIALKGKAGVEAQKT 433
           +DKFIC+REKVGE A+VVIIDM DP+NPIRRPISADSAIMNPASKVIALK      A KT
Sbjct: 44  SDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALK------AGKT 97

Query: 434 LQIFNIEMKSKMKAHTMTEDIVFWK 508
           LQIFNIEMKSKMKAHTMT+D+ FWK
Sbjct: 98  LQIFNIEMKSKMKAHTMTDDVTFWK 122



 Score =  101 bits (242), Expect = 2e-21
 Identities = 46/58 (79%), Positives = 51/58 (87%)
 Frame = +1

Query: 499 FLEGISLNTLALVTKMSVYHWSMEGDSTPVKMFDRHSSLADCQIINYRTDPKQQWLLL 672
           F + ISLNT+ALVT  +VYHWSMEG+S PVKMFDRHSSLA CQIINYRTD KQ+WLLL
Sbjct: 120 FWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLL 177



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/33 (81%), Positives = 31/33 (93%)
 Frame = +3

Query: 156 MAQVLPIRFQEHLQLTNVGINPASISFNTLTME 254
           MAQ+LPIRFQEHLQL N+GINPA+I F+TLTME
Sbjct: 11  MAQILPIRFQEHLQLQNLGINPANIGFSTLTME 43


>BC054489-1|AAH54489.1| 1675|Homo sapiens clathrin, heavy chain (Hc)
           protein.
          Length = 1675

 Score =  140 bits (338), Expect = 5e-33
 Identities = 69/85 (81%), Positives = 75/85 (88%)
 Frame = +2

Query: 254 TDKFICVREKVGETAEVVIIDMADPTNPIRRPISADSAIMNPASKVIALKGKAGVEAQKT 433
           +DKFIC+REKVGE A+VVIIDM DP+NPIRRPISADSAIMNPASKVIALK      A KT
Sbjct: 34  SDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALK------AGKT 87

Query: 434 LQIFNIEMKSKMKAHTMTEDIVFWK 508
           LQIFNIEMKSKMKAHTMT+D+ FWK
Sbjct: 88  LQIFNIEMKSKMKAHTMTDDVTFWK 112



 Score =  101 bits (242), Expect = 2e-21
 Identities = 46/58 (79%), Positives = 51/58 (87%)
 Frame = +1

Query: 499 FLEGISLNTLALVTKMSVYHWSMEGDSTPVKMFDRHSSLADCQIINYRTDPKQQWLLL 672
           F + ISLNT+ALVT  +VYHWSMEG+S PVKMFDRHSSLA CQIINYRTD KQ+WLLL
Sbjct: 110 FWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLL 167



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/33 (81%), Positives = 31/33 (93%)
 Frame = +3

Query: 156 MAQVLPIRFQEHLQLTNVGINPASISFNTLTME 254
           MAQ+LPIRFQEHLQL N+GINPA+I F+TLTME
Sbjct: 1   MAQILPIRFQEHLQLQNLGINPANIGFSTLTME 33


>BC051800-1|AAH51800.1| 1639|Homo sapiens CLTC protein protein.
          Length = 1639

 Score =  140 bits (338), Expect = 5e-33
 Identities = 69/85 (81%), Positives = 75/85 (88%)
 Frame = +2

Query: 254 TDKFICVREKVGETAEVVIIDMADPTNPIRRPISADSAIMNPASKVIALKGKAGVEAQKT 433
           +DKFIC+REKVGE A+VVIIDM DP+NPIRRPISADSAIMNPASKVIALK      A KT
Sbjct: 34  SDKFICIREKVGEQAQVVIIDMNDPSNPIRRPISADSAIMNPASKVIALK------AGKT 87

Query: 434 LQIFNIEMKSKMKAHTMTEDIVFWK 508
           LQIFNIEMKSKMKAHTMT+D+ FWK
Sbjct: 88  LQIFNIEMKSKMKAHTMTDDVTFWK 112



 Score =  101 bits (242), Expect = 2e-21
 Identities = 46/58 (79%), Positives = 51/58 (87%)
 Frame = +1

Query: 499 FLEGISLNTLALVTKMSVYHWSMEGDSTPVKMFDRHSSLADCQIINYRTDPKQQWLLL 672
           F + ISLNT+ALVT  +VYHWSMEG+S PVKMFDRHSSLA CQIINYRTD KQ+WLLL
Sbjct: 110 FWKWISLNTVALVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLL 167



 Score = 61.7 bits (143), Expect = 2e-09
 Identities = 27/33 (81%), Positives = 31/33 (93%)
 Frame = +3

Query: 156 MAQVLPIRFQEHLQLTNVGINPASISFNTLTME 254
           MAQ+LPIRFQEHLQL N+GINPA+I F+TLTME
Sbjct: 1   MAQILPIRFQEHLQLQNLGINPANIGFSTLTME 33


>X95486-1|CAA64752.1| 1640|Homo sapiens clathrin heavy chain
           polypeptide protein.
          Length = 1640

 Score =  132 bits (320), Expect = 8e-31
 Identities = 65/85 (76%), Positives = 73/85 (85%)
 Frame = +2

Query: 254 TDKFICVREKVGETAEVVIIDMADPTNPIRRPISADSAIMNPASKVIALKGKAGVEAQKT 433
           +DKFIC+REKVGE A+V IIDM+DP  PIRRPISA+SAIMNPASKVIALK      A KT
Sbjct: 34  SDKFICIREKVGEQAQVTIIDMSDPMAPIRRPISAESAIMNPASKVIALK------AGKT 87

Query: 434 LQIFNIEMKSKMKAHTMTEDIVFWK 508
           LQIFNIEMKSKMKAHTM E+++FWK
Sbjct: 88  LQIFNIEMKSKMKAHTMAEEVIFWK 112



 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 39/58 (67%), Positives = 50/58 (86%)
 Frame = +1

Query: 499 FLEGISLNTLALVTKMSVYHWSMEGDSTPVKMFDRHSSLADCQIINYRTDPKQQWLLL 672
           F + +S+NT+ALVT+ +VYHWSMEGDS P+KMFDRH+SL  CQ+I+YRTD  Q+WLLL
Sbjct: 110 FWKWVSVNTVALVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLL 167



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 25/33 (75%), Positives = 30/33 (90%)
 Frame = +3

Query: 156 MAQVLPIRFQEHLQLTNVGINPASISFNTLTME 254
           MAQ+LP+RFQEH QL N+GINPA+I F+TLTME
Sbjct: 1   MAQILPVRFQEHFQLQNLGINPANIGFSTLTME 33


>U60803-1|AAB40909.1| 1569|Homo sapiens clathrin heavy chain 2
           protein.
          Length = 1569

 Score =  132 bits (320), Expect = 8e-31
 Identities = 65/85 (76%), Positives = 73/85 (85%)
 Frame = +2

Query: 254 TDKFICVREKVGETAEVVIIDMADPTNPIRRPISADSAIMNPASKVIALKGKAGVEAQKT 433
           +DKFIC+REKVGE A+V IIDM+DP  PIRRPISA+SAIMNPASKVIALK      A KT
Sbjct: 34  SDKFICIREKVGEQAQVTIIDMSDPMAPIRRPISAESAIMNPASKVIALK------AGKT 87

Query: 434 LQIFNIEMKSKMKAHTMTEDIVFWK 508
           LQIFNIEMKSKMKAHTM E+++FWK
Sbjct: 88  LQIFNIEMKSKMKAHTMAEEVIFWK 112



 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 39/58 (67%), Positives = 50/58 (86%)
 Frame = +1

Query: 499 FLEGISLNTLALVTKMSVYHWSMEGDSTPVKMFDRHSSLADCQIINYRTDPKQQWLLL 672
           F + +S+NT+ALVT+ +VYHWSMEGDS P+KMFDRH+SL  CQ+I+YRTD  Q+WLLL
Sbjct: 110 FWKWVSVNTVALVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLL 167



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 25/33 (75%), Positives = 30/33 (90%)
 Frame = +3

Query: 156 MAQVLPIRFQEHLQLTNVGINPASISFNTLTME 254
           MAQ+LP+RFQEH QL N+GINPA+I F+TLTME
Sbjct: 1   MAQILPVRFQEHFQLQNLGINPANIGFSTLTME 33


>U60802-1|AAB40908.1| 1626|Homo sapiens clathrin heavy chain 2
           protein.
          Length = 1626

 Score =  132 bits (320), Expect = 8e-31
 Identities = 65/85 (76%), Positives = 73/85 (85%)
 Frame = +2

Query: 254 TDKFICVREKVGETAEVVIIDMADPTNPIRRPISADSAIMNPASKVIALKGKAGVEAQKT 433
           +DKFIC+REKVGE A+V IIDM+DP  PIRRPISA+SAIMNPASKVIALK      A KT
Sbjct: 34  SDKFICIREKVGEQAQVTIIDMSDPMAPIRRPISAESAIMNPASKVIALK------AGKT 87

Query: 434 LQIFNIEMKSKMKAHTMTEDIVFWK 508
           LQIFNIEMKSKMKAHTM E+++FWK
Sbjct: 88  LQIFNIEMKSKMKAHTMAEEVIFWK 112



 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 39/58 (67%), Positives = 50/58 (86%)
 Frame = +1

Query: 499 FLEGISLNTLALVTKMSVYHWSMEGDSTPVKMFDRHSSLADCQIINYRTDPKQQWLLL 672
           F + +S+NT+ALVT+ +VYHWSMEGDS P+KMFDRH+SL  CQ+I+YRTD  Q+WLLL
Sbjct: 110 FWKWVSVNTVALVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLL 167



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 25/33 (75%), Positives = 30/33 (90%)
 Frame = +3

Query: 156 MAQVLPIRFQEHLQLTNVGINPASISFNTLTME 254
           MAQ+LP+RFQEH QL N+GINPA+I F+TLTME
Sbjct: 1   MAQILPVRFQEHFQLQNLGINPANIGFSTLTME 33


>U41763-1|AAC50494.1| 1640|Homo sapiens muscle clathrin heavy chain
           protein.
          Length = 1640

 Score =  132 bits (320), Expect = 8e-31
 Identities = 65/85 (76%), Positives = 73/85 (85%)
 Frame = +2

Query: 254 TDKFICVREKVGETAEVVIIDMADPTNPIRRPISADSAIMNPASKVIALKGKAGVEAQKT 433
           +DKFIC+REKVGE A+V IIDM+DP  PIRRPISA+SAIMNPASKVIALK      A KT
Sbjct: 34  SDKFICIREKVGEQAQVTIIDMSDPMAPIRRPISAESAIMNPASKVIALK------AGKT 87

Query: 434 LQIFNIEMKSKMKAHTMTEDIVFWK 508
           LQIFNIEMKSKMKAHTM E+++FWK
Sbjct: 88  LQIFNIEMKSKMKAHTMAEEVIFWK 112



 Score = 93.5 bits (222), Expect = 6e-19
 Identities = 39/58 (67%), Positives = 50/58 (86%)
 Frame = +1

Query: 499 FLEGISLNTLALVTKMSVYHWSMEGDSTPVKMFDRHSSLADCQIINYRTDPKQQWLLL 672
           F + +S+NT+ALVT+ +VYHWSMEGDS P+KMFDRH+SL  CQ+I+YRTD  Q+WLLL
Sbjct: 110 FWKWVSVNTVALVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLL 167



 Score = 59.7 bits (138), Expect = 9e-09
 Identities = 25/33 (75%), Positives = 30/33 (90%)
 Frame = +3

Query: 156 MAQVLPIRFQEHLQLTNVGINPASISFNTLTME 254
           MAQ+LP+RFQEH QL N+GINPA+I F+TLTME
Sbjct: 1   MAQILPVRFQEHFQLQNLGINPANIGFSTLTME 33


>U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein.
          Length = 4655

 Score = 29.9 bits (64), Expect = 8.6
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 5/55 (9%)
 Frame = -2

Query: 532 ERVCSVKSLPENNVFGHGVRLHFGFHLDIENLKC-----FLSFNTSFAFQSNDFT 383
           E+VC +    +N+  G   +  FGF LD +   C     FL F++  A +   FT
Sbjct: 671 EQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLIFSSQVAIRGIPFT 725


>AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor
           gp330/megalin precursor protein.
          Length = 4655

 Score = 29.9 bits (64), Expect = 8.6
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 5/55 (9%)
 Frame = -2

Query: 532 ERVCSVKSLPENNVFGHGVRLHFGFHLDIENLKC-----FLSFNTSFAFQSNDFT 383
           E+VC +    +N+  G   +  FGF LD +   C     FL F++  A +   FT
Sbjct: 671 EQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLIFSSQVAIRGIPFT 725


>AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor
           gp330/megalin precursor protein.
          Length = 4655

 Score = 29.9 bits (64), Expect = 8.6
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 5/55 (9%)
 Frame = -2

Query: 532 ERVCSVKSLPENNVFGHGVRLHFGFHLDIENLKC-----FLSFNTSFAFQSNDFT 383
           E+VC +    +N+  G   +  FGF LD +   C     FL F++  A +   FT
Sbjct: 671 EQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLIFSSQVAIRGIPFT 725


>AC008178-1|AAY24266.1|  773|Homo sapiens unknown protein.
          Length = 773

 Score = 29.9 bits (64), Expect = 8.6
 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 5/55 (9%)
 Frame = -2

Query: 532 ERVCSVKSLPENNVFGHGVRLHFGFHLDIENLKC-----FLSFNTSFAFQSNDFT 383
           E+VC +    +N+  G   +  FGF LD +   C     FL F++  A +   FT
Sbjct: 671 EQVCVLSHRTDNDGLGFRCKCTFGFQLDTDERHCIAVQNFLIFSSQVAIRGIPFT 725


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,272,125
Number of Sequences: 237096
Number of extensions: 2027706
Number of successful extensions: 5068
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 4872
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5061
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7615267504
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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