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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= pg--0793.Seq
         (829 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

AF283374-1|AAL38108.1| 1731|Homo sapiens candidate tumor suppres...    43   0.002
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein...    43   0.002
AC108036-1|AAX93208.1|  449|Homo sapiens unknown protein.              43   0.002
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres...    35   0.31 
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein.              35   0.31 
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein...    35   0.31 
X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related prec...    34   0.55 
DQ314873-1|ABC40732.1| 4544|Homo sapiens low density lipoprotein...    34   0.55 
BC110451-1|AAI10452.1| 1042|Homo sapiens corin, serine peptidase...    34   0.55 
AF133845-1|AAD31850.1| 1042|Homo sapiens corin protein.                34   0.55 
AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein receptor-re...    34   0.55 
AB209498-1|BAD92735.1| 2359|Homo sapiens low density lipoprotein...    34   0.72 
AB111888-1|BAC98376.1| 1322|Homo sapiens KIAA2036 protein protein.     33   0.95 
AY899851-1|AAX85199.1|  730|Homo sapiens LGR8.1 protein.               32   2.2  
AL159161-1|CAI17102.1|  754|Homo sapiens relaxin/insulin-like fa...    32   2.2  
AL138708-1|CAH73785.1|  754|Homo sapiens relaxin/insulin-like fa...    32   2.2  
AF453828-1|AAL73946.1|  754|Homo sapiens G protein-coupled recep...    32   2.2  
AF403384-1|AAL69324.2|  754|Homo sapiens LGR8 protein.                 32   2.2  
X55077-1|CAA38905.1|  591|Homo sapiens alpha-2 macroglobulin rec...    31   6.7  
U83192-1|AAC52113.1|  767|Homo sapiens post-synaptic density pro...    31   6.7  
U68138-1|AAB07736.1|  321|Homo sapiens PSD-95 protein.                 31   6.7  
BC040533-1|AAH40533.1|  549|Homo sapiens DLG4 protein protein.         31   6.7  
AF156495-1|AAD56173.1|  767|Homo sapiens post-synaptic density 9...    31   6.7  

>AF283374-1|AAL38108.1| 1731|Homo sapiens candidate tumor suppressor
            protein protein.
          Length = 1731

 Score = 42.7 bits (96), Expect = 0.002
 Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
 Frame = +2

Query: 104  DAVKNCKLKNKERKIKPLLYTEEPLCQDGFLACGDSTCIERGLFCNGEKDLAMDLMKI-L 280
            D + +CK K+ E+    LLY E   C+ GF  C +  CI  G  C+GE D   +  ++  
Sbjct: 1607 DGIPHCKDKSDEK----LLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDC 1662

Query: 281  VILTTTQIELRHA----IPRS 331
             + T   +E R A    IPRS
Sbjct: 1663 KVSTCATVEFRCADGTCIPRS 1683


>AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein
            receptor related protein-deleted in tumor protein.
          Length = 4599

 Score = 42.7 bits (96), Expect = 0.002
 Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
 Frame = +2

Query: 104  DAVKNCKLKNKERKIKPLLYTEEPLCQDGFLACGDSTCIERGLFCNGEKDLAMDLMKI-L 280
            D + +CK K+ E+    LLY E   C+ GF  C +  CI  G  C+GE D   +  ++  
Sbjct: 2531 DGIPHCKDKSDEK----LLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDC 2586

Query: 281  VILTTTQIELRHA----IPRS 331
             + T   +E R A    IPRS
Sbjct: 2587 KVSTCATVEFRCADGTCIPRS 2607



 Score = 35.1 bits (77), Expect = 0.31
 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 1/55 (1%)
 Frame = +2

Query: 98   WK-DAVKNCKLKNKERKIKPLLYTEEPLCQDGFLACGDSTCIERGLFCNGEKDLA 259
            WK D  ++CK    E+  +P      P C      C    CI   L CNGE D A
Sbjct: 3570 WKCDGHEDCKYGEDEKSCEPA----SPTCSSREYICASDGCISASLKCNGEYDCA 3620


>AC108036-1|AAX93208.1|  449|Homo sapiens unknown protein.
          Length = 449

 Score = 42.7 bits (96), Expect = 0.002
 Identities = 28/81 (34%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
 Frame = +2

Query: 104 DAVKNCKLKNKERKIKPLLYTEEPLCQDGFLACGDSTCIERGLFCNGEKDLAMDLMKI-L 280
           D + +CK K+ E+    LLY E   C+ GF  C +  CI  G  C+GE D   +  ++  
Sbjct: 264 DGIPHCKDKSDEK----LLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDC 319

Query: 281 VILTTTQIELRHA----IPRS 331
            + T   +E R A    IPRS
Sbjct: 320 KVSTCATVEFRCADGTCIPRS 340


>AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppressor
            protein protein.
          Length = 1537

 Score = 35.1 bits (77), Expect = 0.31
 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 1/55 (1%)
 Frame = +2

Query: 98   WK-DAVKNCKLKNKERKIKPLLYTEEPLCQDGFLACGDSTCIERGLFCNGEKDLA 259
            WK D  ++CK    E+  +P      P C      C    CI   L CNGE D A
Sbjct: 894  WKCDGHEDCKYGEDEKSCEPA----SPTCSSREYICASDGCISASLKCNGEYDCA 944


>AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein.
          Length = 1126

 Score = 35.1 bits (77), Expect = 0.31
 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 1/55 (1%)
 Frame = +2

Query: 98  WK-DAVKNCKLKNKERKIKPLLYTEEPLCQDGFLACGDSTCIERGLFCNGEKDLA 259
           WK D  ++CK    E+  +P      P C      C    CI   L CNGE D A
Sbjct: 428 WKCDGHEDCKYGEDEKSCEPA----SPTCSSREYICASDGCISASLKCNGEYDCA 478


>AB209707-1|BAD92944.1| 1720|Homo sapiens low density
           lipoprotein-related protein 1B variant protein.
          Length = 1720

 Score = 35.1 bits (77), Expect = 0.31
 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 1/55 (1%)
 Frame = +2

Query: 98  WK-DAVKNCKLKNKERKIKPLLYTEEPLCQDGFLACGDSTCIERGLFCNGEKDLA 259
           WK D  ++CK    E+  +P      P C      C    CI   L CNGE D A
Sbjct: 691 WKCDGHEDCKYGEDEKSCEPA----SPTCSSREYICASDGCISASLKCNGEYDCA 741


>X13916-1|CAA32112.1| 4544|Homo sapiens LDL-receptor related
           precursor (AA -19 to 4525) protein.
          Length = 4544

 Score = 34.3 bits (75), Expect = 0.55
 Identities = 13/31 (41%), Positives = 17/31 (54%)
 Frame = +2

Query: 161 YTEEPLCQDGFLACGDSTCIERGLFCNGEKD 253
           Y   P CQ G  AC +S CI+    C+G+ D
Sbjct: 848 YVPPPQCQPGEFACANSRCIQERWKCDGDND 878



 Score = 33.9 bits (74), Expect = 0.72
 Identities = 18/50 (36%), Positives = 24/50 (48%)
 Frame = +2

Query: 104  DAVKNCKLKNKERKIKPLLYTEEPLCQDGFLACGDSTCIERGLFCNGEKD 253
            D V +CK K+ E   KP  Y     C+  F  C +  C+   L+CNG  D
Sbjct: 2545 DGVPHCKDKSDE---KPS-YCNSRRCKKTFRQCSNGRCVSNMLWCNGADD 2590



 Score = 30.7 bits (66), Expect = 6.7
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 9/73 (12%)
 Frame = +1

Query: 256  GDGSDENSCDID----NDPNRAPPC-DSSQCVLPD----CFCSEDGTVIPGDLPARDVPQ 408
            GDGSDE  C ID    +    A  C D ++CV  +    C C      +PG    +D+ +
Sbjct: 3768 GDGSDEEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINE 3827

Query: 409  MITITFDDAINNN 447
             +       + NN
Sbjct: 3828 CLRFGTCSQLCNN 3840


>DQ314873-1|ABC40732.1| 4544|Homo sapiens low density
           lipoprotein-related protein 1 (alpha-2-macroglobulin
           receptor) protein.
          Length = 4544

 Score = 34.3 bits (75), Expect = 0.55
 Identities = 13/31 (41%), Positives = 17/31 (54%)
 Frame = +2

Query: 161 YTEEPLCQDGFLACGDSTCIERGLFCNGEKD 253
           Y   P CQ G  AC +S CI+    C+G+ D
Sbjct: 848 YVPPPQCQPGEFACANSRCIQERWKCDGDND 878



 Score = 33.9 bits (74), Expect = 0.72
 Identities = 18/50 (36%), Positives = 24/50 (48%)
 Frame = +2

Query: 104  DAVKNCKLKNKERKIKPLLYTEEPLCQDGFLACGDSTCIERGLFCNGEKD 253
            D V +CK K+ E   KP  Y     C+  F  C +  C+   L+CNG  D
Sbjct: 2545 DGVPHCKDKSDE---KPS-YCNSRRCKKTFRQCSNGRCVSNMLWCNGADD 2590



 Score = 30.7 bits (66), Expect = 6.7
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 9/73 (12%)
 Frame = +1

Query: 256  GDGSDENSCDID----NDPNRAPPC-DSSQCVLPD----CFCSEDGTVIPGDLPARDVPQ 408
            GDGSDE  C ID    +    A  C D ++CV  +    C C      +PG    +D+ +
Sbjct: 3768 GDGSDEEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINE 3827

Query: 409  MITITFDDAINNN 447
             +       + NN
Sbjct: 3828 CLRFGTCSQLCNN 3840


>BC110451-1|AAI10452.1| 1042|Homo sapiens corin, serine peptidase
           protein.
          Length = 1042

 Score = 34.3 bits (75), Expect = 0.55
 Identities = 12/25 (48%), Positives = 16/25 (64%)
 Frame = +2

Query: 179 CQDGFLACGDSTCIERGLFCNGEKD 253
           CQD  L C +  C+ R L+C+GE D
Sbjct: 655 CQDDELECANHACVSRDLWCDGEAD 679


>AF133845-1|AAD31850.1| 1042|Homo sapiens corin protein.
          Length = 1042

 Score = 34.3 bits (75), Expect = 0.55
 Identities = 12/25 (48%), Positives = 16/25 (64%)
 Frame = +2

Query: 179 CQDGFLACGDSTCIERGLFCNGEKD 253
           CQD  L C +  C+ R L+C+GE D
Sbjct: 655 CQDDELECANHACVSRDLWCDGEAD 679


>AF058427-1|AAC64265.1| 4544|Homo sapiens lipoprotein
           receptor-related protein protein.
          Length = 4544

 Score = 34.3 bits (75), Expect = 0.55
 Identities = 13/31 (41%), Positives = 17/31 (54%)
 Frame = +2

Query: 161 YTEEPLCQDGFLACGDSTCIERGLFCNGEKD 253
           Y   P CQ G  AC +S CI+    C+G+ D
Sbjct: 848 YVPPPQCQPGEFACANSRCIQERWKCDGDND 878



 Score = 33.9 bits (74), Expect = 0.72
 Identities = 18/50 (36%), Positives = 24/50 (48%)
 Frame = +2

Query: 104  DAVKNCKLKNKERKIKPLLYTEEPLCQDGFLACGDSTCIERGLFCNGEKD 253
            D V +CK K+ E   KP  Y     C+  F  C +  C+   L+CNG  D
Sbjct: 2545 DGVPHCKDKSDE---KPS-YCNSRRCKKTFRQCSNGRCVSNMLWCNGADD 2590



 Score = 30.7 bits (66), Expect = 6.7
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 9/73 (12%)
 Frame = +1

Query: 256  GDGSDENSCDID----NDPNRAPPC-DSSQCVLPD----CFCSEDGTVIPGDLPARDVPQ 408
            GDGSDE  C ID    +    A  C D ++CV  +    C C      +PG    +D+ +
Sbjct: 3768 GDGSDEEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINE 3827

Query: 409  MITITFDDAINNN 447
             +       + NN
Sbjct: 3828 CLRFGTCSQLCNN 3840


>AB209498-1|BAD92735.1| 2359|Homo sapiens low density
           lipoprotein-related protein 1 variant protein.
          Length = 2359

 Score = 33.9 bits (74), Expect = 0.72
 Identities = 18/50 (36%), Positives = 24/50 (48%)
 Frame = +2

Query: 104 DAVKNCKLKNKERKIKPLLYTEEPLCQDGFLACGDSTCIERGLFCNGEKD 253
           D V +CK K+ E   KP  Y     C+  F  C +  C+   L+CNG  D
Sbjct: 361 DGVPHCKDKSDE---KPS-YCNSRRCKKTFRQCSNGRCVSNMLWCNGADD 406



 Score = 30.7 bits (66), Expect = 6.7
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 9/73 (12%)
 Frame = +1

Query: 256  GDGSDENSCDID----NDPNRAPPC-DSSQCVLPD----CFCSEDGTVIPGDLPARDVPQ 408
            GDGSDE  C ID    +    A  C D ++CV  +    C C      +PG    +D+ +
Sbjct: 1583 GDGSDEEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINE 1642

Query: 409  MITITFDDAINNN 447
             +       + NN
Sbjct: 1643 CLRFGTCSQLCNN 1655


>AB111888-1|BAC98376.1| 1322|Homo sapiens KIAA2036 protein protein.
          Length = 1322

 Score = 33.5 bits (73), Expect = 0.95
 Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
 Frame = +2

Query: 164 TEEPL--CQDGFLACGDSTCIERGLFCNGEKD 253
           T+EP   C  G LAC D  C+   L C+G  D
Sbjct: 331 TDEPSYPCPQGLLACADGRCLPPALLCDGHPD 362


>AY899851-1|AAX85199.1|  730|Homo sapiens LGR8.1 protein.
          Length = 730

 Score = 32.3 bits (70), Expect = 2.2
 Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
 Frame = +2

Query: 173 PLCQDGFLACGDST-CIERGLFCNGEKD 253
           P CQ G+  CG+ T C+ R   C+G+ D
Sbjct: 43  PSCQKGYFPCGNLTKCLPRAFHCDGKDD 70


>AL159161-1|CAI17102.1|  754|Homo sapiens relaxin/insulin-like
           family peptide receptor 2 protein.
          Length = 754

 Score = 32.3 bits (70), Expect = 2.2
 Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
 Frame = +2

Query: 173 PLCQDGFLACGDST-CIERGLFCNGEKD 253
           P CQ G+  CG+ T C+ R   C+G+ D
Sbjct: 43  PSCQKGYFPCGNLTKCLPRAFHCDGKDD 70


>AL138708-1|CAH73785.1|  754|Homo sapiens relaxin/insulin-like
           family peptide receptor 2 protein.
          Length = 754

 Score = 32.3 bits (70), Expect = 2.2
 Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
 Frame = +2

Query: 173 PLCQDGFLACGDST-CIERGLFCNGEKD 253
           P CQ G+  CG+ T C+ R   C+G+ D
Sbjct: 43  PSCQKGYFPCGNLTKCLPRAFHCDGKDD 70


>AF453828-1|AAL73946.1|  754|Homo sapiens G protein-coupled receptor
           affecting testicular descent protein.
          Length = 754

 Score = 32.3 bits (70), Expect = 2.2
 Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
 Frame = +2

Query: 173 PLCQDGFLACGDST-CIERGLFCNGEKD 253
           P CQ G+  CG+ T C+ R   C+G+ D
Sbjct: 43  PSCQKGYFPCGNLTKCLPRAFHCDGKDD 70


>AF403384-1|AAL69324.2|  754|Homo sapiens LGR8 protein.
          Length = 754

 Score = 32.3 bits (70), Expect = 2.2
 Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
 Frame = +2

Query: 173 PLCQDGFLACGDST-CIERGLFCNGEKD 253
           P CQ G+  CG+ T C+ R   C+G+ D
Sbjct: 43  PSCQKGYFPCGNLTKCLPRAFHCDGKDD 70


>X55077-1|CAA38905.1|  591|Homo sapiens alpha-2 macroglobulin
           receptor protein.
          Length = 591

 Score = 30.7 bits (66), Expect = 6.7
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 9/73 (12%)
 Frame = +1

Query: 256 GDGSDENSCDID----NDPNRAPPC-DSSQCVLPD----CFCSEDGTVIPGDLPARDVPQ 408
           GDGSDE  C ID    +    A  C D ++CV  +    C C      +PG    +D+ +
Sbjct: 494 GDGSDEEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINE 553

Query: 409 MITITFDDAINNN 447
            +       + NN
Sbjct: 554 CLRFGTCSQLCNN 566


>U83192-1|AAC52113.1|  767|Homo sapiens post-synaptic density
           protein 95 protein.
          Length = 767

 Score = 30.7 bits (66), Expect = 6.7
 Identities = 17/46 (36%), Positives = 24/46 (52%)
 Frame = -3

Query: 143 YAPCS*AYNFSQHLSNRRSVSQYRRTNRPGNV*LVFPRQYTG*RRD 6
           YAP     ++SQHL N  S S Y  T+ P  +    PR+Y+   +D
Sbjct: 298 YAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD 343


>U68138-1|AAB07736.1|  321|Homo sapiens PSD-95 protein.
          Length = 321

 Score = 30.7 bits (66), Expect = 6.7
 Identities = 17/46 (36%), Positives = 24/46 (52%)
 Frame = -3

Query: 143 YAPCS*AYNFSQHLSNRRSVSQYRRTNRPGNV*LVFPRQYTG*RRD 6
           YAP     ++SQHL N  S S Y  T+ P  +    PR+Y+   +D
Sbjct: 218 YAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD 263


>BC040533-1|AAH40533.1|  549|Homo sapiens DLG4 protein protein.
          Length = 549

 Score = 30.7 bits (66), Expect = 6.7
 Identities = 17/46 (36%), Positives = 24/46 (52%)
 Frame = -3

Query: 143 YAPCS*AYNFSQHLSNRRSVSQYRRTNRPGNV*LVFPRQYTG*RRD 6
           YAP     ++SQHL N  S S Y  T+ P  +    PR+Y+   +D
Sbjct: 80  YAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD 125


>AF156495-1|AAD56173.1|  767|Homo sapiens post-synaptic density 95
           protein.
          Length = 767

 Score = 30.7 bits (66), Expect = 6.7
 Identities = 17/46 (36%), Positives = 24/46 (52%)
 Frame = -3

Query: 143 YAPCS*AYNFSQHLSNRRSVSQYRRTNRPGNV*LVFPRQYTG*RRD 6
           YAP     ++SQHL N  S S Y  T+ P  +    PR+Y+   +D
Sbjct: 298 YAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD 343


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,928,638
Number of Sequences: 237096
Number of extensions: 2482403
Number of successful extensions: 10950
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 10271
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10938
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10370898348
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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