Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= pg--0689.Seq
(772 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP], mitoch... 162 8e-39
UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate... 151 1e-35
UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial... 151 1e-35
UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular organ... 147 3e-34
UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein; ... 146 4e-34
UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5; ... 130 5e-29
UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridi... 110 4e-23
UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2; ... 105 9e-22
UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1; ... 104 2e-21
UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4; Eukaryot... 80 5e-14
UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase... 58 2e-07
UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma j... 53 7e-06
UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3... 52 1e-05
UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5; Gammapro... 50 6e-05
UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase... 49 1e-04
UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza sa... 46 0.001
UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_Q59HI0 Cluster: Transcriptional activator; n=4; Gammapr... 36 1.1
UniRef50_A0C1D3 Cluster: Chromosome undetermined scaffold_141, w... 34 3.4
UniRef50_Q46FZ3 Cluster: Putative uncharacterized protein; n=1; ... 33 7.9
>UniRef50_P48735 Cluster: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH); n=493;
cellular organisms|Rep: Isocitrate dehydrogenase [NADP],
mitochondrial precursor (EC 1.1.1.42) (Oxalosuccinate
decarboxylase) (IDH) (NADP(+)-specific ICDH) - Homo
sapiens (Human)
Length = 452
Score = 162 bits (394), Expect = 8e-39
Identities = 73/89 (82%), Positives = 77/89 (86%)
Frame = +1
Query: 250 KEYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGW 429
++Y+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICKNIPRLV GW
Sbjct: 105 QKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGW 164
Query: 430 DKPIIIGRHAHADQYKATDFVVPGAGILK 516
KPI IGRHAH DQYKATDFV AG K
Sbjct: 165 TKPITIGRHAHGDQYKATDFVADRAGTFK 193
Score = 107 bits (257), Expect = 3e-22
Identities = 46/88 (52%), Positives = 64/88 (72%), Gaps = 1/88 (1%)
Frame = +3
Query: 498 RCWYLEIIFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLY 674
R +++F P+ G +K V+ + GV + M+NTD SI FAHS F++A+ +K+PLY
Sbjct: 188 RAGTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLY 247
Query: 675 LSTKNTILKKYDGRFKDIFQDIYDREYK 758
+STKNTILK YDGRFKDIFQ+I+D+ YK
Sbjct: 248 MSTKNTILKAYDGRFKDIFQEIFDKHYK 275
Score = 88.6 bits (210), Expect = 1e-16
Identities = 44/68 (64%), Positives = 52/68 (76%), Gaps = 1/68 (1%)
Frame = +2
Query: 47 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELNVYDLGMENRDKTDDQ 223
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 224 VTIDCAEA 247
VTID A A
Sbjct: 96 VTIDSALA 103
>UniRef50_UPI0000F1EC8D Cluster: PREDICTED: similar to Isocitrate
dehydrogenase 1 (NADP+), soluble; n=2; Danio rerio|Rep:
PREDICTED: similar to Isocitrate dehydrogenase 1
(NADP+), soluble - Danio rerio
Length = 206
Score = 151 bits (367), Expect = 1e-35
Identities = 70/92 (76%), Positives = 77/92 (83%), Gaps = 4/92 (4%)
Frame = +1
Query: 250 KEYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGW 429
+ YNVGIKCATITPDEKRVEEFKLK+MW+SPNGTIRNILGGTVFREAIICKNIPRLV GW
Sbjct: 72 RRYNVGIKCATITPDEKRVEEFKLKQMWRSPNGTIRNILGGTVFREAIICKNIPRLVPGW 131
Query: 430 DKPIIIGRHAHADQYKA----TDFVVPGAGIL 513
KPIIIGRHAH DQ + T + P A ++
Sbjct: 132 IKPIIIGRHAHGDQDRRSCANTQIMTPNASLI 163
Score = 99 bits (238), Expect = 6e-20
Identities = 44/67 (65%), Positives = 59/67 (88%), Gaps = 1/67 (1%)
Frame = +2
Query: 56 YNMS-KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELNVYDLGMENRDKTDDQVTI 232
+ MS KIKAG VV++ GDEMTR+IW+LIKEKLI P+L+++L+ YDLGMENRD TDD+VT+
Sbjct: 6 FKMSQKIKAGSVVEMQGDEMTRVIWELIKEKLIFPYLELDLHSYDLGMENRDATDDKVTV 65
Query: 233 DCAEAIK 253
+ AEA++
Sbjct: 66 EAAEAVR 72
>UniRef50_Q0CXI1 Cluster: Isocitrate dehydrogenase, mitochondrial;
n=2; Eurotiomycetidae|Rep: Isocitrate dehydrogenase,
mitochondrial - Aspergillus terreus (strain NIH 2624)
Length = 466
Score = 151 bits (367), Expect = 1e-35
Identities = 69/89 (77%), Positives = 75/89 (84%)
Frame = +1
Query: 250 KEYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGW 429
K+Y VG+KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFRE I+ IPRLV GW
Sbjct: 121 KKYGVGVKCATITPDEARVEEFKLKKMWLSPNGTIRNILGGTVFREPIVIPAIPRLVPGW 180
Query: 430 DKPIIIGRHAHADQYKATDFVVPGAGILK 516
KPIIIGRHA DQY+ATD V+PG G L+
Sbjct: 181 TKPIIIGRHAFGDQYRATDRVIPGPGKLE 209
Score = 110 bits (265), Expect = 3e-23
Identities = 51/85 (60%), Positives = 68/85 (80%), Gaps = 1/85 (1%)
Frame = +3
Query: 510 LEIIFKPESGEAIKHVVHEYK-GAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTK 686
LE+++ P +G+ V++++ G GVA++M+NTD SI FAHSSFK AL + PLY+STK
Sbjct: 208 LELVYTPANGQPESVQVYDFQSGGGVAMSMYNTDDSIRGFAHSSFKMALLKGLPLYMSTK 267
Query: 687 NTILKKYDGRFKDIFQDIYDREYKK 761
NTILK+YDGRFKDIFQ+IY+ EYKK
Sbjct: 268 NTILKRYDGRFKDIFQEIYEAEYKK 292
Score = 34.7 bits (76), Expect = 2.6
Identities = 14/21 (66%), Positives = 19/21 (90%)
Frame = +2
Query: 191 GMENRDKTDDQVTIDCAEAIK 253
G+E RD+TDD+VT++ AEAIK
Sbjct: 101 GIEYRDQTDDKVTVEAAEAIK 121
>UniRef50_Q9SRZ6 Cluster: F12P19.10 protein; n=26; cellular
organisms|Rep: F12P19.10 protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 410
Score = 147 bits (356), Expect = 3e-34
Identities = 66/88 (75%), Positives = 73/88 (82%)
Frame = +1
Query: 250 KEYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGW 429
K+YNV IKCATITPDE RV EF LK+MW+SPNGTIRNIL GTVFRE IICKN+P+LV GW
Sbjct: 67 KKYNVAIKCATITPDEGRVTEFGLKQMWRSPNGTIRNILNGTVFREPIICKNVPKLVPGW 126
Query: 430 DKPIIIGRHAHADQYKATDFVVPGAGIL 513
KPI IGRHA DQY+ATD V+ G G L
Sbjct: 127 TKPICIGRHAFGDQYRATDAVIKGPGKL 154
Score = 92.7 bits (220), Expect = 9e-18
Identities = 44/85 (51%), Positives = 59/85 (69%)
Frame = +3
Query: 510 LEIIFKPESGEAIKHVVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKN 689
L + F+ + G+ V GVA+AM+NTD SI FA +S A ++K+PLYLSTKN
Sbjct: 154 LTMTFEGKDGKTETEVFTFTGEGGVAMAMYNTDESIRAFADASMNTAYEKKWPLYLSTKN 213
Query: 690 TILKKYDGRFKDIFQDIYDREYKKR 764
TILKKYDGRFKDIFQ++Y+ +K +
Sbjct: 214 TILKKYDGRFKDIFQEVYEASWKSK 238
Score = 81.0 bits (191), Expect = 3e-14
Identities = 36/63 (57%), Positives = 51/63 (80%), Gaps = 1/63 (1%)
Frame = +2
Query: 68 KIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELNVYDLGMENRDKTDDQVTIDCAE 244
KIK A P+V++ GDEMTR+IW IK+KLI PF+++++ +DLG+ +RD TDD+VTI+ AE
Sbjct: 5 KIKVANPIVEMDGDEMTRVIWKSIKDKLITPFVELDIKYFDLGLPHRDATDDKVTIESAE 64
Query: 245 AIK 253
A K
Sbjct: 65 ATK 67
>UniRef50_Q8LPJ5 Cluster: Isocitrate dehydrogenase-like protein;
n=6; core eudicotyledons|Rep: Isocitrate
dehydrogenase-like protein - Arabidopsis thaliana
(Mouse-ear cress)
Length = 485
Score = 146 bits (355), Expect = 4e-34
Identities = 66/88 (75%), Positives = 73/88 (82%)
Frame = +1
Query: 253 EYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWD 432
+YNV IKCATITPDE RV+EF LK MW+SPNGTIRNIL GTVFRE I+C NIPRLV GW+
Sbjct: 138 KYNVAIKCATITPDEGRVKEFGLKSMWRSPNGTIRNILDGTVFREPIMCSNIPRLVPGWE 197
Query: 433 KPIIIGRHAHADQYKATDFVVPGAGILK 516
KPI IGRHA DQY+ATD V+ G G LK
Sbjct: 198 KPICIGRHAFGDQYRATDTVIKGPGKLK 225
Score = 110 bits (264), Expect = 4e-23
Identities = 51/86 (59%), Positives = 68/86 (79%), Gaps = 1/86 (1%)
Frame = +3
Query: 510 LEIIFKPESGEA-IKHVVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTK 686
L+++F PE G A ++ V+++KG GVALAM+N D SI FA SS AL +K+PLYLSTK
Sbjct: 224 LKMVFVPEDGNAPVELDVYDFKGPGVALAMYNVDESIRAFAESSMAMALTKKWPLYLSTK 283
Query: 687 NTILKKYDGRFKDIFQDIYDREYKKR 764
NTILKKYDGRFKDIFQ++Y+ +K++
Sbjct: 284 NTILKKYDGRFKDIFQEVYEANWKQK 309
Score = 83.8 bits (198), Expect = 4e-15
Identities = 34/55 (61%), Positives = 48/55 (87%)
Frame = +2
Query: 83 PVVDILGDEMTRIIWDLIKEKLILPFLDIELNVYDLGMENRDKTDDQVTIDCAEA 247
P+V++ GDEMTR+IW +IKEKLILP+LD+++ +DLG+ NRD TDD+VT++ AEA
Sbjct: 81 PIVEMDGDEMTRVIWSMIKEKLILPYLDLDIKYFDLGILNRDATDDKVTVESAEA 135
>UniRef50_A2WMU2 Cluster: Putative uncharacterized protein; n=5;
Eukaryota|Rep: Putative uncharacterized protein - Oryza
sativa subsp. indica (Rice)
Length = 475
Score = 130 bits (313), Expect = 5e-29
Identities = 68/106 (64%), Positives = 72/106 (67%), Gaps = 18/106 (16%)
Frame = +1
Query: 253 EYNVGIKCATITP------------------DEKRVEEFKLKKMWKSPNGTIRNILGGTV 378
+YNV IKCATITP DE RV+EF L MWKSPNGTIRNIL GTV
Sbjct: 93 KYNVAIKCATITPVLDTQFKFDFGRTIHEPTDEGRVKEFNLSAMWKSPNGTIRNILNGTV 152
Query: 379 FREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGILK 516
FRE IICKNIPRLV GW KPI IGRHA DQY+ATD V+ G G LK
Sbjct: 153 FREPIICKNIPRLVPGWIKPICIGRHAFGDQYRATDTVIKGPGKLK 198
Score = 89.8 bits (213), Expect = 6e-17
Identities = 45/86 (52%), Positives = 62/86 (72%), Gaps = 1/86 (1%)
Frame = +3
Query: 510 LEIIFKPESGEAIKHVVHEYKGAG-VALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTK 686
L+++F E I+ V + GAG VAL+M+NTD SI FA +S A +++PLYLSTK
Sbjct: 197 LKLVFDGRE-EQIELDVFNFTGAGGVALSMYNTDESIWAFAEASMNMAYQKRWPLYLSTK 255
Query: 687 NTILKKYDGRFKDIFQDIYDREYKKR 764
NTILKKYDGRFKDIFQ+ Y+ +++ +
Sbjct: 256 NTILKKYDGRFKDIFQENYETKWRAK 281
Score = 75.4 bits (177), Expect = 1e-12
Identities = 32/49 (65%), Positives = 40/49 (81%)
Frame = +2
Query: 101 GDEMTRIIWDLIKEKLILPFLDIELNVYDLGMENRDKTDDQVTIDCAEA 247
GDEMTR+IW IK+KLI PFLD+++ YDLG+ NRD T D+VTI+ AEA
Sbjct: 42 GDEMTRVIWKWIKDKLIFPFLDLDIKYYDLGLPNRDATGDKVTIESAEA 90
>UniRef50_A5N5L9 Cluster: Idh; n=2; Bacteria|Rep: Idh - Clostridium
kluyveri DSM 555
Length = 401
Score = 110 bits (264), Expect = 4e-23
Identities = 49/86 (56%), Positives = 62/86 (72%)
Frame = +1
Query: 250 KEYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGW 429
K+Y VG+KCATITP+ KRV+E+ LK MWKSPNGTIR IL GTVFR II +I L+ W
Sbjct: 66 KKYGVGVKCATITPNAKRVKEYNLKSMWKSPNGTIRAILDGTVFRTPIIVNSIRPLMRTW 125
Query: 430 DKPIIIGRHAHADQYKATDFVVPGAG 507
+KPI + RHA+ D Y+ ++ V G
Sbjct: 126 EKPITVARHAYGDVYRDVEYKVEEPG 151
Score = 89.8 bits (213), Expect = 6e-17
Identities = 40/82 (48%), Positives = 53/82 (64%)
Frame = +3
Query: 510 LEIIFKPESGEAIKHVVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKN 689
+E++F E GE + +H + G GV + M N D SI FA S F +ALD L+ ++K+
Sbjct: 153 MELVFTSEKGEETRQTLHVFNGPGVVMGMHNLDKSIESFARSCFNYALDMNQNLWFASKD 212
Query: 690 TILKKYDGRFKDIFQDIYDREY 755
TI K YD RFKDIFQ+IYD EY
Sbjct: 213 TISKTYDHRFKDIFQEIYDTEY 234
Score = 74.1 bits (174), Expect = 3e-12
Identities = 33/63 (52%), Positives = 49/63 (77%), Gaps = 1/63 (1%)
Frame = +2
Query: 68 KIKAG-PVVDILGDEMTRIIWDLIKEKLILPFLDIELNVYDLGMENRDKTDDQVTIDCAE 244
KIK P+V++ GDEMTRIIW +IKE L+ P++D++ YDLG+ R++T+D++TI+ A
Sbjct: 4 KIKMNVPLVEMDGDEMTRIIWKMIKELLLEPYIDLKTEYYDLGLVKRNETNDEITIEAAN 63
Query: 245 AIK 253
AIK
Sbjct: 64 AIK 66
>UniRef50_A2XVE4 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 371
Score = 105 bits (253), Expect = 9e-22
Identities = 47/83 (56%), Positives = 64/83 (77%)
Frame = +3
Query: 516 IIFKPESGEAIKHVVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKNTI 695
I+ P+ E ++ V+ +KG GVAL+M+N D SI FA SS AL +K+PLYLSTKNTI
Sbjct: 30 ILSVPDGAEPVELNVYNFKGPGVALSMYNVDESIRAFAESSMAMALSKKWPLYLSTKNTI 89
Query: 696 LKKYDGRFKDIFQDIYDREYKKR 764
LKKYDGRFKDIFQ++Y+ ++K++
Sbjct: 90 LKKYDGRFKDIFQEVYEEKWKEK 112
Score = 77.8 bits (183), Expect = 3e-13
Identities = 34/51 (66%), Positives = 43/51 (84%)
Frame = +3
Query: 612 SIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKR 764
SI FA SS AL +K+PLYLSTKNTILKKYDGRFKDIFQ++Y+ ++K++
Sbjct: 158 SIRAFAESSMAMALSKKWPLYLSTKNTILKKYDGRFKDIFQEVYEEKWKEK 208
Score = 62.1 bits (144), Expect = 1e-08
Identities = 24/32 (75%), Positives = 30/32 (93%)
Frame = +1
Query: 328 MWKSPNGTIRNILGGTVFREAIICKNIPRLVT 423
MW+SPNGTIRNIL GTVFRE I+CKN+PR+++
Sbjct: 1 MWRSPNGTIRNILNGTVFREPILCKNVPRILS 32
>UniRef50_A5ZVX5 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 417
Score = 104 bits (250), Expect = 2e-21
Identities = 47/86 (54%), Positives = 59/86 (68%)
Frame = +1
Query: 250 KEYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGW 429
K+Y V +KCATITP+ R++E+ LKKM+KSPNGTIR IL GTVFR I+ K I V W
Sbjct: 80 KKYGVAVKCATITPNHARMDEYDLKKMYKSPNGTIRAILDGTVFRAPIVVKGIEPCVRNW 139
Query: 430 DKPIIIGRHAHADQYKATDFVVPGAG 507
KPI + RHA+ D YK T+ + G
Sbjct: 140 KKPITLARHAYGDIYKNTEMYIDKPG 165
Score = 85.4 bits (202), Expect = 1e-15
Identities = 37/85 (43%), Positives = 55/85 (64%)
Frame = +3
Query: 510 LEIIFKPESGEAIKHVVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKN 689
+E+++ E GE + +V E+K GVA+ M N ASI FA S F +ALD K ++ K+
Sbjct: 167 VELVYTSEDGEEKRSLVQEFKAPGVAMGMHNMTASIESFARSCFNYALDTKQDVWFGAKD 226
Query: 690 TILKKYDGRFKDIFQDIYDREYKKR 764
TI K YD +FK++FQ ++D E+K R
Sbjct: 227 TISKTYDAKFKEVFQTVFDTEFKDR 251
Score = 82.2 bits (194), Expect = 1e-14
Identities = 37/65 (56%), Positives = 51/65 (78%), Gaps = 1/65 (1%)
Frame = +2
Query: 62 MSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELNVYDLGMENRDKTDDQVTIDC 238
M KI+ P+V++ GDEMTRI+W +IK++L+LPF+D+ YDLG+ R++TDDQVTID
Sbjct: 16 MEKIQMTTPLVEMDGDEMTRILWKMIKDELLLPFIDLNTEYYDLGLNYRNETDDQVTIDA 75
Query: 239 AEAIK 253
AEA K
Sbjct: 76 AEATK 80
>UniRef50_Q4VCC2 Cluster: Isocitrate dehydrogenase; n=4;
Eukaryota|Rep: Isocitrate dehydrogenase - Saltugilia
latimeri
Length = 158
Score = 80.2 bits (189), Expect = 5e-14
Identities = 34/54 (62%), Positives = 44/54 (81%)
Frame = +3
Query: 603 TDASIIDFAHSSFKFALDRKYPLYLSTKNTILKKYDGRFKDIFQDIYDREYKKR 764
TD SI FA +S A ++K+PLYLSTKNTILKKYDGRFKDIFQ++Y++ +K +
Sbjct: 1 TDESIYSFAEASMTTAYEKKWPLYLSTKNTILKKYDGRFKDIFQEVYEKSWKSK 54
>UniRef50_Q2K7T8 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=1; Rhizobium etli CFN 42|Rep: NADP-dependent
isocitrate dehydrogenase protein - Rhizobium etli
(strain CFN 42 / ATCC 51251)
Length = 437
Score = 58.4 bits (135), Expect = 2e-07
Identities = 27/79 (34%), Positives = 47/79 (59%)
Frame = -2
Query: 489 KVSCFVLISMSMTSNDDGFVPPCYKSRYILANNSLPENSTTKNITDGPIRAFPHFLQFKF 310
+V C VL++ S+T++DD P ++R + A++ L E+ +N++D +RA PHFL+ +F
Sbjct: 279 EVGCAVLVAESVTADDDRLRPAGNEARNVAADDRLAEDDAAENVSDRAVRALPHFLEIEF 338
Query: 309 FNSLLIRSYGRTFDAHIVF 253
++ IR D VF
Sbjct: 339 LDAGFIRRDRCALDTDAVF 357
Score = 39.1 bits (87), Expect = 0.12
Identities = 17/56 (30%), Positives = 34/56 (60%)
Frame = -1
Query: 253 LYGLSTINCNLIISLITIFHTQVVDI*FNVQERKNQLFFDKIPDYSGHFITKDVNN 86
L G+ ++ +L++ + IF +VV + V+ R +QL D++PD + HFI ++ +
Sbjct: 358 LDGVGGVDRHLVVGGVAIFDREVVIVDIEVEIRMDQLILDELPDDACHFIAVEIGD 413
>UniRef50_Q5DBI8 Cluster: SJCHGC09598 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC09598 protein - Schistosoma
japonicum (Blood fluke)
Length = 129
Score = 53.2 bits (122), Expect = 7e-06
Identities = 28/48 (58%), Positives = 31/48 (64%)
Frame = -3
Query: 392 IASLKTVPPRILRMVPLGLFHIXXXXXXXXXXXSGVMVAHLMPTLYSL 249
+ S KTVPPRILR+VP G HI SGVMVAHL+PTLY L
Sbjct: 1 MGSRKTVPPRILRIVPFGDSHIFFKLNSLTRCSSGVMVAHLIPTLYFL 48
Score = 36.7 bits (81), Expect = 0.64
Identities = 24/47 (51%), Positives = 26/47 (55%)
Frame = -2
Query: 261 IVFFMASAQSIVT*SSVLSRFSIPKS*TFNSMSKKGRISFSLIRSQI 121
+ F +ASA SIVT S V SR PKS S S G IS IRS I
Sbjct: 45 LYFLIASAPSIVTWSLVRSRLGRPKSKYLQSTSINGNISCCFIRSII 91
>UniRef50_Q00WM7 Cluster: COG0538: Isocitrate dehydrogenases; n=3;
Ostreococcus|Rep: COG0538: Isocitrate dehydrogenases -
Ostreococcus tauri
Length = 429
Score = 52.4 bits (120), Expect = 1e-05
Identities = 28/64 (43%), Positives = 40/64 (62%), Gaps = 1/64 (1%)
Frame = +2
Query: 65 SKIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDI-ELNVYDLGMENRDKTDDQVTIDCA 241
SKI A P+V + G+EMT + DLI+ + I P +D+ +DL +NRD T+D+V D
Sbjct: 24 SKITAAPMVYVRGEEMTAYVMDLIRSRWIEPRVDVGGWETFDLRAKNRDDTEDRVLRDVI 83
Query: 242 EAIK 253
EA K
Sbjct: 84 EAGK 87
Score = 47.6 bits (108), Expect = 3e-04
Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Frame = +1
Query: 280 TITPDEKRVEEFKLKKMWKSPNGTIRNILGG-TVFREAIICKNIPRLVTGWDKPIIIGRH 456
T+TP +V+ L+K W SPNG +R G T+ R+ I +I + G+ KP++ RH
Sbjct: 97 TVTPTADQVKRLGLRKSWGSPNGAMRRGWNGITISRDTI---HIDGVELGYKKPVLFERH 153
Query: 457 AHADQYKA 480
A +Y A
Sbjct: 154 AVGGEYSA 161
>UniRef50_A3JDN6 Cluster: Isocitrate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Isocitrate dehydrogenase -
Marinobacter sp. ELB17
Length = 582
Score = 50.0 bits (114), Expect = 6e-05
Identities = 26/85 (30%), Positives = 45/85 (52%)
Frame = +3
Query: 510 LEIIFKPESGEAIKHVVHEYKGAGVALAMFNTDASIIDFAHSSFKFALDRKYPLYLSTKN 689
++++F +SG ++ + K L N A + +AH F+ A+D K YL K+
Sbjct: 165 VKLLFVGKSGNPVELHRRDVKKGDPWLLATNDIADVKAWAHRFFQRAIDEKRDAYLGLKD 224
Query: 690 TILKKYDGRFKDIFQDIYDREYKKR 764
T++ YDG + + IY +EYKK+
Sbjct: 225 TVIAGYDGVMRAAIEAIYKQEYKKQ 249
Score = 41.9 bits (94), Expect = 0.017
Identities = 24/65 (36%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +2
Query: 62 MSKIKA-GPVVDILGDEMTRIIWDLIKEKLILPFLDIELNVYDLGMENRDKTDDQVTIDC 238
++KI+ P+V + GDEM ++ ++ I +K + L IEL DL E+R T+ QV +
Sbjct: 2 VNKIQVESPLVILHGDEMAQVAFEEILKKFVTTRLAIELIEIDLSAEHRFLTNGQVIFEA 61
Query: 239 AEAIK 253
EA+K
Sbjct: 62 IEALK 66
>UniRef50_A3K670 Cluster: NADP-dependent isocitrate dehydrogenase
protein; n=2; Rhodobacteraceae|Rep: NADP-dependent
isocitrate dehydrogenase protein - Sagittula stellata
E-37
Length = 459
Score = 48.8 bits (111), Expect = 1e-04
Identities = 20/69 (28%), Positives = 42/69 (60%)
Frame = -2
Query: 474 VLISMSMTSNDDGFVPPCYKSRYILANNSLPENSTTKNITDGPIRAFPHFLQFKFFNSLL 295
VL++ + ++ DG P +++R++ A++ L E+ +++ D + PH L+ +F ++LL
Sbjct: 315 VLVAEGVPAHHDGRGPARHEARHVAADDRLAEDDAAQDVADRAVGRLPHLLETEFLDTLL 374
Query: 294 IRSYGRTFD 268
+R R FD
Sbjct: 375 VRGDRRAFD 383
>UniRef50_Q40658 Cluster: Isocitrate dehydrogenase; n=1; Oryza
sativa|Rep: Isocitrate dehydrogenase - Oryza sativa
(Rice)
Length = 61
Score = 46.0 bits (104), Expect = 0.001
Identities = 18/26 (69%), Positives = 22/26 (84%)
Frame = +2
Query: 101 GDEMTRIIWDLIKEKLILPFLDIELN 178
GDEMTRI W IK+KLI PFLD+++N
Sbjct: 36 GDEMTRIFWQSIKDKLIFPFLDLDIN 61
>UniRef50_A4VDP7 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 141
Score = 44.4 bits (100), Expect = 0.003
Identities = 32/65 (49%), Positives = 38/65 (58%)
Frame = -2
Query: 249 MASAQSIVT*SSVLSRFSIPKS*TFNSMSKKGRISFSLIRSQIILVISSPRMSTTGPAFI 70
+A A S VT S V SRFSI +S S G +S SLI Q+I VISSP ST G F+
Sbjct: 39 IAQAASKVTQSLVASRFSIERSQYLISAEINGNMSLSLIIFQMIRVISSPSKSTIG--FL 96
Query: 69 LDILY 55
IL+
Sbjct: 97 TLILF 101
>UniRef50_Q59HI0 Cluster: Transcriptional activator; n=4;
Gammaproteobacteria|Rep: Transcriptional activator -
Vibrio vulnificus
Length = 290
Score = 35.9 bits (79), Expect = 1.1
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 3/79 (3%)
Frame = +3
Query: 492 CPRCWYLEIIFKPESGEAIKHVVHEYKGAGVALAMFNTDASIIDFAHS---SFKFALDRK 662
C W L+ +F+ E+G + H V E K + A + +TD +ID A S + + A R
Sbjct: 23 CWSRWQLQRVFQAETGLTVAHYVRELKLSTAAEMLLDTDQRVIDVALSLGFNSEIAFSRA 82
Query: 663 YPLYLSTKNTILKKYDGRF 719
+ + +K RF
Sbjct: 83 FKQLFGYSPRLYRKQAQRF 101
>UniRef50_A0C1D3 Cluster: Chromosome undetermined scaffold_141,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_141,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 490
Score = 34.3 bits (75), Expect = 3.4
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Frame = +3
Query: 507 YLEIIFKPESGEAIKHVVHEYKGAGV---ALAMFNTDASIIDFAHSSFKFALDRKYPLYL 677
++E KP +K VH +L++ ++ I + H SFK L + +
Sbjct: 72 FIEEDGKPPETTCLKLAVHRLDNTPQIIQSLSIITSNNIINQWRHYSFKLPLPKLNNQDV 131
Query: 678 STKNTILKKYDGRFKDIFQDIYDREYK 758
STKN ++ Y+G + F+ R++K
Sbjct: 132 STKNQKIRAYNGSYSINFESTQQRDFK 158
>UniRef50_Q46FZ3 Cluster: Putative uncharacterized protein; n=1;
Methanosarcina barkeri str. Fusaro|Rep: Putative
uncharacterized protein - Methanosarcina barkeri (strain
Fusaro / DSM 804)
Length = 459
Score = 33.1 bits (72), Expect = 7.9
Identities = 16/42 (38%), Positives = 25/42 (59%)
Frame = +2
Query: 65 SKIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELNVYDL 190
S K P+V I+ +T ++W L+K LI P L + N+Y+L
Sbjct: 252 SFFKISPLVVIISSFITIVLWSLLKHDLIFPLLK-DNNLYEL 292
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 767,191,158
Number of Sequences: 1657284
Number of extensions: 15799369
Number of successful extensions: 40551
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 38885
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40540
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 64615845515
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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