Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= pg--0533.Seq
(724 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC001705-1|AAH01705.1| 654|Homo sapiens serine active site cont... 35 0.26
AL590703-2|CAH70240.1| 531|Homo sapiens serine active site cont... 35 0.26
AL590703-1|CAH70239.1| 654|Homo sapiens serine active site cont... 35 0.26
AL135907-2|CAI42500.1| 531|Homo sapiens serine active site cont... 35 0.26
AL135907-1|CAI42499.1| 654|Homo sapiens serine active site cont... 35 0.26
AK027823-1|BAB55393.1| 654|Homo sapiens protein ( Homo sapiens ... 35 0.26
M33308-1|AAA61283.1| 1066|Homo sapiens VCL protein. 32 2.4
BC039174-1|AAH39174.1| 1066|Homo sapiens vinculin protein. 32 2.4
AL731576-5|CAI39673.1| 1066|Homo sapiens vinculin protein. 32 2.4
AL731576-1|CAI39669.1| 806|Homo sapiens vinculin protein. 32 2.4
AL596247-9|CAI13972.1| 1066|Homo sapiens vinculin protein. 32 2.4
U84744-1|AAB87737.1| 1531|Homo sapiens Chediak-Higashi syndrome ... 31 5.5
U72192-1|AAB39697.1| 1475|Homo sapiens lysosomal trafficking reg... 31 5.5
U70064-1|AAB41533.1| 2001|Homo sapiens lysosomal trafficking reg... 31 5.5
U67615-1|AAB41309.1| 3801|Homo sapiens beige protein homolog pro... 31 5.5
AL390765-1|CAI14952.1| 3801|Homo sapiens lysosomal trafficking r... 31 5.5
AL121997-1|CAI18987.1| 3801|Homo sapiens lysosomal trafficking r... 31 5.5
BT007447-1|AAP36115.1| 197|Homo sapiens crystallin, beta A2 pro... 30 9.6
BC006285-1|AAH06285.1| 197|Homo sapiens crystallin, beta A2 pro... 30 9.6
AF166331-1|AAD45388.1| 197|Homo sapiens beta crystallin A2 prot... 30 9.6
AF043909-1|AAC19168.1| 1373|Homo sapiens gastric mucin protein. 30 9.6
AC097468-3|AAX88918.1| 197|Homo sapiens unknown protein. 30 9.6
>BC001705-1|AAH01705.1| 654|Homo sapiens serine active site
containing 1 protein.
Length = 654
Score = 35.1 bits (77), Expect = 0.26
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +2
Query: 449 DVIFVHGLYGSLSNTWRQGDGNQ 517
DV+F+HGL G+ TWRQ D Q
Sbjct: 395 DVLFIHGLMGAAFKTWRQQDSEQ 417
>AL590703-2|CAH70240.1| 531|Homo sapiens serine active site
containing 1 protein.
Length = 531
Score = 35.1 bits (77), Expect = 0.26
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +2
Query: 449 DVIFVHGLYGSLSNTWRQGDGNQ 517
DV+F+HGL G+ TWRQ D Q
Sbjct: 395 DVLFIHGLMGAAFKTWRQQDSEQ 417
>AL590703-1|CAH70239.1| 654|Homo sapiens serine active site
containing 1 protein.
Length = 654
Score = 35.1 bits (77), Expect = 0.26
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +2
Query: 449 DVIFVHGLYGSLSNTWRQGDGNQ 517
DV+F+HGL G+ TWRQ D Q
Sbjct: 395 DVLFIHGLMGAAFKTWRQQDSEQ 417
>AL135907-2|CAI42500.1| 531|Homo sapiens serine active site
containing 1 protein.
Length = 531
Score = 35.1 bits (77), Expect = 0.26
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +2
Query: 449 DVIFVHGLYGSLSNTWRQGDGNQ 517
DV+F+HGL G+ TWRQ D Q
Sbjct: 395 DVLFIHGLMGAAFKTWRQQDSEQ 417
>AL135907-1|CAI42499.1| 654|Homo sapiens serine active site
containing 1 protein.
Length = 654
Score = 35.1 bits (77), Expect = 0.26
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +2
Query: 449 DVIFVHGLYGSLSNTWRQGDGNQ 517
DV+F+HGL G+ TWRQ D Q
Sbjct: 395 DVLFIHGLMGAAFKTWRQQDSEQ 417
>AK027823-1|BAB55393.1| 654|Homo sapiens protein ( Homo sapiens
cDNA FLJ14917 fis, clone PLACE1007112. ).
Length = 654
Score = 35.1 bits (77), Expect = 0.26
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +2
Query: 449 DVIFVHGLYGSLSNTWRQGDGNQ 517
DV+F+HGL G+ TWRQ D Q
Sbjct: 395 DVLFIHGLMGAAFKTWRQQDSEQ 417
>M33308-1|AAA61283.1| 1066|Homo sapiens VCL protein.
Length = 1066
Score = 31.9 bits (69), Expect = 2.4
Identities = 35/153 (22%), Positives = 58/153 (37%), Gaps = 7/153 (4%)
Frame = +1
Query: 226 ATSDCTRISFGATVVCFELMEDGHRFPASISRRQTAANQSETSQNEAQGAGDRPPGPRAS 405
A ++S G V+ ++ + A + +Q+ A + + +QN P G
Sbjct: 349 AMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQI 408
Query: 406 RGVRGPARAAFSY---PRRH---LRPWA-IRILKQHLASRRWKPTYKSEPELKTLINHTS 564
RG AR P+ LR I L LA R + PE + L +
Sbjct: 409 RGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLR-RQGKGDSPEARALAKQVA 467
Query: 565 KTLDNADSVKTNNAIADNDNVTAGNEVNGSFKR 663
L N + KTN A+A++ A + G ++
Sbjct: 468 TALQNLQT-KTNRAVANSRPAKAAVHLEGKIEQ 499
>BC039174-1|AAH39174.1| 1066|Homo sapiens vinculin protein.
Length = 1066
Score = 31.9 bits (69), Expect = 2.4
Identities = 35/153 (22%), Positives = 58/153 (37%), Gaps = 7/153 (4%)
Frame = +1
Query: 226 ATSDCTRISFGATVVCFELMEDGHRFPASISRRQTAANQSETSQNEAQGAGDRPPGPRAS 405
A ++S G V+ ++ + A + +Q+ A + + +QN P G
Sbjct: 349 AMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQI 408
Query: 406 RGVRGPARAAFSY---PRRH---LRPWA-IRILKQHLASRRWKPTYKSEPELKTLINHTS 564
RG AR P+ LR I L LA R + PE + L +
Sbjct: 409 RGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLR-RQGKGDSPEARALAKQVA 467
Query: 565 KTLDNADSVKTNNAIADNDNVTAGNEVNGSFKR 663
L N + KTN A+A++ A + G ++
Sbjct: 468 TALQNLQT-KTNRAVANSRPAKAAVHLEGKIEQ 499
>AL731576-5|CAI39673.1| 1066|Homo sapiens vinculin protein.
Length = 1066
Score = 31.9 bits (69), Expect = 2.4
Identities = 35/153 (22%), Positives = 58/153 (37%), Gaps = 7/153 (4%)
Frame = +1
Query: 226 ATSDCTRISFGATVVCFELMEDGHRFPASISRRQTAANQSETSQNEAQGAGDRPPGPRAS 405
A ++S G V+ ++ + A + +Q+ A + + +QN P G
Sbjct: 349 AMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQI 408
Query: 406 RGVRGPARAAFSY---PRRH---LRPWA-IRILKQHLASRRWKPTYKSEPELKTLINHTS 564
RG AR P+ LR I L LA R + PE + L +
Sbjct: 409 RGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLR-RQGKGDSPEARALAKQVA 467
Query: 565 KTLDNADSVKTNNAIADNDNVTAGNEVNGSFKR 663
L N + KTN A+A++ A + G ++
Sbjct: 468 TALQNLQT-KTNRAVANSRPAKAAVHLEGKIEQ 499
>AL731576-1|CAI39669.1| 806|Homo sapiens vinculin protein.
Length = 806
Score = 31.9 bits (69), Expect = 2.4
Identities = 35/153 (22%), Positives = 58/153 (37%), Gaps = 7/153 (4%)
Frame = +1
Query: 226 ATSDCTRISFGATVVCFELMEDGHRFPASISRRQTAANQSETSQNEAQGAGDRPPGPRAS 405
A ++S G V+ ++ + A + +Q+ A + + +QN P G
Sbjct: 21 AMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQI 80
Query: 406 RGVRGPARAAFSY---PRRH---LRPWA-IRILKQHLASRRWKPTYKSEPELKTLINHTS 564
RG AR P+ LR I L LA R + PE + L +
Sbjct: 81 RGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLR-RQGKGDSPEARALAKQVA 139
Query: 565 KTLDNADSVKTNNAIADNDNVTAGNEVNGSFKR 663
L N + KTN A+A++ A + G ++
Sbjct: 140 TALQNLQT-KTNRAVANSRPAKAAVHLEGKIEQ 171
>AL596247-9|CAI13972.1| 1066|Homo sapiens vinculin protein.
Length = 1066
Score = 31.9 bits (69), Expect = 2.4
Identities = 35/153 (22%), Positives = 58/153 (37%), Gaps = 7/153 (4%)
Frame = +1
Query: 226 ATSDCTRISFGATVVCFELMEDGHRFPASISRRQTAANQSETSQNEAQGAGDRPPGPRAS 405
A ++S G V+ ++ + A + +Q+ A + + +QN P G
Sbjct: 349 AMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQI 408
Query: 406 RGVRGPARAAFSY---PRRH---LRPWA-IRILKQHLASRRWKPTYKSEPELKTLINHTS 564
RG AR P+ LR I L LA R + PE + L +
Sbjct: 409 RGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLR-RQGKGDSPEARALAKQVA 467
Query: 565 KTLDNADSVKTNNAIADNDNVTAGNEVNGSFKR 663
L N + KTN A+A++ A + G ++
Sbjct: 468 TALQNLQT-KTNRAVANSRPAKAAVHLEGKIEQ 499
>U84744-1|AAB87737.1| 1531|Homo sapiens Chediak-Higashi syndrome
protein short isoform protein.
Length = 1531
Score = 30.7 bits (66), Expect = 5.5
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +1
Query: 82 NVFRLYQQGQTIVNVISGFASTLCQDN 162
NVF L QQG T+ N++ GF S L QD+
Sbjct: 1306 NVFLLMQQG-TVKNLLGGFLSILTQDD 1331
>U72192-1|AAB39697.1| 1475|Homo sapiens lysosomal trafficking
regulator LYST protein.
Length = 1475
Score = 30.7 bits (66), Expect = 5.5
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +1
Query: 82 NVFRLYQQGQTIVNVISGFASTLCQDN 162
NVF L QQG T+ N++ GF S L QD+
Sbjct: 1306 NVFLLMQQG-TVKNLLGGFLSILTQDD 1331
>U70064-1|AAB41533.1| 2001|Homo sapiens lysosomal trafficking
regulator protein.
Length = 2001
Score = 30.7 bits (66), Expect = 5.5
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +1
Query: 82 NVFRLYQQGQTIVNVISGFASTLCQDN 162
NVF L QQG T+ N++ GF S L QD+
Sbjct: 1306 NVFLLMQQG-TVKNLLGGFLSILTQDD 1331
>U67615-1|AAB41309.1| 3801|Homo sapiens beige protein homolog protein.
Length = 3801
Score = 30.7 bits (66), Expect = 5.5
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +1
Query: 82 NVFRLYQQGQTIVNVISGFASTLCQDN 162
NVF L QQG T+ N++ GF S L QD+
Sbjct: 1306 NVFLLMQQG-TVKNLLGGFLSILTQDD 1331
>AL390765-1|CAI14952.1| 3801|Homo sapiens lysosomal trafficking
regulator protein.
Length = 3801
Score = 30.7 bits (66), Expect = 5.5
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +1
Query: 82 NVFRLYQQGQTIVNVISGFASTLCQDN 162
NVF L QQG T+ N++ GF S L QD+
Sbjct: 1306 NVFLLMQQG-TVKNLLGGFLSILTQDD 1331
>AL121997-1|CAI18987.1| 3801|Homo sapiens lysosomal trafficking
regulator protein.
Length = 3801
Score = 30.7 bits (66), Expect = 5.5
Identities = 15/27 (55%), Positives = 19/27 (70%)
Frame = +1
Query: 82 NVFRLYQQGQTIVNVISGFASTLCQDN 162
NVF L QQG T+ N++ GF S L QD+
Sbjct: 1306 NVFLLMQQG-TVKNLLGGFLSILTQDD 1331
>BT007447-1|AAP36115.1| 197|Homo sapiens crystallin, beta A2
protein.
Length = 197
Score = 29.9 bits (64), Expect = 9.6
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Frame = -1
Query: 514 VSIALTPSVA*GSV*PMDEDDVEGRRRRLVQDHALHARHGVQVVGPRHPELRFD---WSR 344
+S A P A S+ DE+D +GRR RL+ D A G PR ++ + W
Sbjct: 1 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGL---PRVRSVKVENGVWVA 57
Query: 343 FDLRQSDGD*SMQENGDRP 287
F+ G + E GD P
Sbjct: 58 FEYPDFQGQQFILEKGDYP 76
>BC006285-1|AAH06285.1| 197|Homo sapiens crystallin, beta A2
protein.
Length = 197
Score = 29.9 bits (64), Expect = 9.6
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Frame = -1
Query: 514 VSIALTPSVA*GSV*PMDEDDVEGRRRRLVQDHALHARHGVQVVGPRHPELRFD---WSR 344
+S A P A S+ DE+D +GRR RL+ D A G PR ++ + W
Sbjct: 1 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGL---PRVRSVKVENGVWVA 57
Query: 343 FDLRQSDGD*SMQENGDRP 287
F+ G + E GD P
Sbjct: 58 FEYPDFQGQQFILEKGDYP 76
>AF166331-1|AAD45388.1| 197|Homo sapiens beta crystallin A2
protein.
Length = 197
Score = 29.9 bits (64), Expect = 9.6
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Frame = -1
Query: 514 VSIALTPSVA*GSV*PMDEDDVEGRRRRLVQDHALHARHGVQVVGPRHPELRFD---WSR 344
+S A P A S+ DE+D +GRR RL+ D A G PR ++ + W
Sbjct: 1 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGL---PRVRSVKVENGVWVA 57
Query: 343 FDLRQSDGD*SMQENGDRP 287
F+ G + E GD P
Sbjct: 58 FEYPDFQGQQFILEKGDYP 76
>AF043909-1|AAC19168.1| 1373|Homo sapiens gastric mucin protein.
Length = 1373
Score = 29.9 bits (64), Expect = 9.6
Identities = 16/46 (34%), Positives = 21/46 (45%)
Frame = +1
Query: 376 GDRPPGPRASRGVRGPARAAFSYPRRHLRPWAIRILKQHLASRRWK 513
G RPPGP A + V GP A + R WA+ + + WK
Sbjct: 154 GQRPPGPAALQPVWGPHSARAAATPRWKPGWALSSCGTTMTACCWK 199
>AC097468-3|AAX88918.1| 197|Homo sapiens unknown protein.
Length = 197
Score = 29.9 bits (64), Expect = 9.6
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Frame = -1
Query: 514 VSIALTPSVA*GSV*PMDEDDVEGRRRRLVQDHALHARHGVQVVGPRHPELRFD---WSR 344
+S A P A S+ DE+D +GRR RL+ D A G PR ++ + W
Sbjct: 1 MSSAPAPGPAPASLTLWDEEDFQGRRCRLLSDCANVCERGGL---PRVRSVKVENGVWVA 57
Query: 343 FDLRQSDGD*SMQENGDRP 287
F+ G + E GD P
Sbjct: 58 FEYPDFQGQQFILEKGDYP 76
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,242,993
Number of Sequences: 237096
Number of extensions: 2206540
Number of successful extensions: 11206
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 9919
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 11186
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8511181328
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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