Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= pg--0400X.Seq
(492 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mR... 100 3e-21
BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase, cAMP-de... 100 3e-21
BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein. 100 3e-21
M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein ki... 98 2e-20
BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase, cAMP-de... 98 2e-20
AC006387-1|AAS07389.1| 306|Homo sapiens unknown protein. 98 2e-20
M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein ki... 79 6e-15
BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase, cAMP-de... 79 6e-15
BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein. 79 6e-15
M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein ki... 77 3e-14
M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein ki... 77 3e-14
BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase, cAMP-de... 77 3e-14
BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase, cAMP-de... 77 3e-14
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 74 3e-13
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 48 2e-05
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 48 2e-05
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 48 2e-05
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 46 7e-05
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 46 7e-05
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 46 7e-05
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 46 7e-05
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 46 7e-05
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 46 7e-05
BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein. 46 7e-05
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 46 7e-05
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 46 7e-05
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 46 7e-05
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 46 7e-05
AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase, cGMP-de... 46 7e-05
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 46 7e-05
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 46 7e-05
AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase, cGMP-de... 46 7e-05
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 46 7e-05
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 46 7e-05
AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN ... 40 0.006
AB209681-1|BAD92918.1| 643|Homo sapiens RAP guanine-nucleotide-... 38 0.019
U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine nu... 38 0.025
BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein. 38 0.025
BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide ... 38 0.025
AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein. 38 0.025
BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide ... 35 0.18
BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein. 35 0.18
BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein. 35 0.18
BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide ... 35 0.18
AJ238850-1|CAB52754.1| 1203|Homo sapiens hyperpolarization-activ... 35 0.18
AJ133727-1|CAB42630.1| 889|Homo sapiens hyperpolarization-activ... 35 0.18
AJ132429-1|CAB42604.1| 1203|Homo sapiens hyperpolarization-activ... 35 0.18
AJ012582-1|CAB42602.1| 889|Homo sapiens hyperpolarization-activ... 35 0.18
AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide... 35 0.18
AF065164-1|AAC28444.2| 889|Homo sapiens hyperpolarization-activ... 35 0.18
AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2 prot... 35 0.18
U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine nu... 34 0.23
U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine nu... 34 0.23
EF157730-1|ABO15447.1| 35|Homo sapiens type II cAMP-dependent ... 33 0.41
AB029009-1|BAA83038.1| 902|Homo sapiens KIAA1086 protein protein. 31 2.2
AB013004-1|BAA36573.1| 87|Homo sapiens CD22 protein. 31 2.2
BC036847-1|AAH36847.1| 272|Homo sapiens neurogenin 2 protein. 31 2.9
AF303002-1|AAG40770.1| 250|Homo sapiens neurogenin 2 protein. 31 2.9
BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein. 30 3.8
BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for IM... 30 3.8
AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization acti... 30 3.8
AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization activ... 30 3.8
AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1 prot... 30 3.8
AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein. 30 3.8
AK097840-1|BAC05181.1| 452|Homo sapiens protein ( Homo sapiens ... 30 5.0
BC040640-1|AAH40640.1| 802|Homo sapiens Rho guanine nucleotide ... 29 6.6
BC012982-1|AAH12982.1| 706|Homo sapiens ARHGEF19 protein protein. 29 6.6
AL109627-9|CAI22567.1| 502|Homo sapiens Rho guanine nucleotide ... 29 6.6
AL109627-8|CAI22566.1| 802|Homo sapiens Rho guanine nucleotide ... 29 6.6
AK091281-1|BAC03627.1| 502|Homo sapiens protein ( Homo sapiens ... 29 6.6
AL590007-1|CAI12790.2| 3169|Homo sapiens FRAS1 related extracell... 29 8.8
AL354819-1|CAI16761.2| 3169|Homo sapiens FRAS1 related extracell... 29 8.8
>X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mRNA
for the RII-alpha subunit of cAMP dependent protein
kinase. ).
Length = 404
Score = 100 bits (239), Expect = 3e-21
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
GDDGDNFYVIE G +D+LVT D++ V Y+ GSFGELALMYN P AA++ + + G+
Sbjct: 170 GDDGDNFYVIERGTYDILVTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIVATSEGS 228
Query: 432 LWAMDRHTFRRILLKSAFKK 491
LW +DR TFRRI++K+ KK
Sbjct: 229 LWGLDRVTFRRIIVKNNAKK 248
Score = 64.5 bits (150), Expect = 2e-10
Identities = 32/65 (49%), Positives = 44/65 (67%)
Frame = +2
Query: 2 EEPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDA 181
E P +RFN RR SV AETY+P+E++ D + PK+D QR RL EA + ILLF++LD
Sbjct: 87 EVPVPSRFN-RRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQ 145
Query: 182 HKCSR 196
+ S+
Sbjct: 146 EQLSQ 150
Score = 40.3 bits (90), Expect = 0.004
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 8/81 (9%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVT--------GDDRVEKVVHTYEGSGSFGELALMYNMPLAAS 407
G+ D+FY+IE+G +L+ G ++ ++ ++G FGELAL+ N P AAS
Sbjct: 292 GEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQ-YFGELALVTNKPRAAS 350
Query: 408 VRSQTAGALWAMDRHTFRRIL 470
+ MD F R+L
Sbjct: 351 AYAVGDVKCLVMDVQAFERLL 371
>BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, alpha protein.
Length = 382
Score = 100 bits (239), Expect = 3e-21
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
GDDGDNFYVIE G +D+LVT D++ V Y+ GSFGELALMYN P AA++ + + G+
Sbjct: 170 GDDGDNFYVIERGTYDILVTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIVATSEGS 228
Query: 432 LWAMDRHTFRRILLKSAFKK 491
LW +DR TFRRI++K+ KK
Sbjct: 229 LWGLDRVTFRRIIVKNNAKK 248
Score = 64.5 bits (150), Expect = 2e-10
Identities = 32/65 (49%), Positives = 44/65 (67%)
Frame = +2
Query: 2 EEPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDA 181
E P +RFN RR SV AETY+P+E++ D + PK+D QR RL EA + ILLF++LD
Sbjct: 87 EVPVPSRFN-RRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQ 145
Query: 182 HKCSR 196
+ S+
Sbjct: 146 EQLSQ 150
Score = 29.9 bits (64), Expect = 5.0
Identities = 20/53 (37%), Positives = 27/53 (50%)
Frame = +3
Query: 312 GDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGALWAMDRHTFRRIL 470
G+ VE + ++G FGELAL+ N P AAS + MD F R+L
Sbjct: 299 GNQEVE-IARCHKGQ-YFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLL 349
>BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein.
Length = 382
Score = 100 bits (239), Expect = 3e-21
Identities = 46/80 (57%), Positives = 60/80 (75%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
GDDGDNFYVIE G +D+LVT D++ V Y+ GSFGELALMYN P AA++ + + G+
Sbjct: 170 GDDGDNFYVIERGTYDILVTKDNQTRSVGQ-YDNRGSFGELALMYNTPRAATIVATSEGS 228
Query: 432 LWAMDRHTFRRILLKSAFKK 491
LW +DR TFRRI++K+ KK
Sbjct: 229 LWGLDRVTFRRIIVKNNAKK 248
Score = 64.5 bits (150), Expect = 2e-10
Identities = 32/65 (49%), Positives = 44/65 (67%)
Frame = +2
Query: 2 EEPPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDA 181
E P +RFN RR SV AETY+P+E++ D + PK+D QR RL EA + ILLF++LD
Sbjct: 87 EVPVPSRFN-RRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQ 145
Query: 182 HKCSR 196
+ S+
Sbjct: 146 EQLSQ 150
Score = 29.9 bits (64), Expect = 5.0
Identities = 20/53 (37%), Positives = 27/53 (50%)
Frame = +3
Query: 312 GDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGALWAMDRHTFRRIL 470
G+ VE + ++G FGELAL+ N P AAS + MD F R+L
Sbjct: 299 GNQEVE-IARCHKGQ-YFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLL 349
>M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein
kinase subunit RII-beta protein.
Length = 418
Score = 97.9 bits (233), Expect = 2e-20
Identities = 46/80 (57%), Positives = 58/80 (72%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
GDDGDNFYVI+ G FD+ V D V + V Y+ GSFGELALMYN P AA++ + + GA
Sbjct: 185 GDDGDNFYVIDRGTFDIYVKCDG-VGRCVGNYDNRGSFGELALMYNTPRAATITATSPGA 243
Query: 432 LWAMDRHTFRRILLKSAFKK 491
LW +DR TFRRI++K+ KK
Sbjct: 244 LWGLDRVTFRRIIVKNNAKK 263
Score = 58.8 bits (136), Expect = 9e-09
Identities = 29/63 (46%), Positives = 42/63 (66%)
Frame = +2
Query: 8 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAHK 187
P + RF RR SV AE Y+P+E++ D + + PK+D QR RL EA + ILLF++LD +
Sbjct: 104 PVINRFT-RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQ 162
Query: 188 CSR 196
S+
Sbjct: 163 MSQ 165
Score = 39.1 bits (87), Expect = 0.008
Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVT--GDDRVEK--VVHTYEGSGS--FGELALMYNMPLAASVR 413
GD D+F+++E+G + + G VE+ V S FGELAL+ N P AAS
Sbjct: 307 GDSADSFFIVESGEVKITMKRKGKSEVEENGAVEMPRCSRGQYFGELALVTNKPRAASAH 366
Query: 414 SQTAGALWAMDRHTFRRIL 470
+ AMD F R+L
Sbjct: 367 AIGTVKCLAMDVQAFERLL 385
Score = 33.5 bits (73), Expect = 0.41
Identities = 16/24 (66%), Positives = 18/24 (75%)
Frame = +1
Query: 184 QMQQVLDAMFGKRSEPGEYVIRQG 255
QM QVLDAMF K + GE+VI QG
Sbjct: 162 QMSQVLDAMFEKLVKDGEHVIDQG 185
>BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, beta protein.
Length = 418
Score = 97.9 bits (233), Expect = 2e-20
Identities = 46/80 (57%), Positives = 58/80 (72%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
GDDGDNFYVI+ G FD+ V D V + V Y+ GSFGELALMYN P AA++ + + GA
Sbjct: 185 GDDGDNFYVIDRGTFDIYVKCDG-VGRCVGNYDNRGSFGELALMYNTPRAATITATSPGA 243
Query: 432 LWAMDRHTFRRILLKSAFKK 491
LW +DR TFRRI++K+ KK
Sbjct: 244 LWGLDRVTFRRIIVKNNAKK 263
Score = 58.8 bits (136), Expect = 9e-09
Identities = 29/63 (46%), Positives = 42/63 (66%)
Frame = +2
Query: 8 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAHK 187
P + RF RR SV AE Y+P+E++ D + + PK+D QR RL EA + ILLF++LD +
Sbjct: 104 PVINRFT-RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQ 162
Query: 188 CSR 196
S+
Sbjct: 163 MSQ 165
Score = 39.5 bits (88), Expect = 0.006
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 7/80 (8%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVT--GDDRVEK-----VVHTYEGSGSFGELALMYNMPLAASV 410
GD D+F+++E+G + + G VE+ + G FGELAL+ N P AAS
Sbjct: 307 GDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQ-YFGELALVTNKPRAASA 365
Query: 411 RSQTAGALWAMDRHTFRRIL 470
+ AMD F R+L
Sbjct: 366 HAIGTVKCLAMDVQAFERLL 385
Score = 33.5 bits (73), Expect = 0.41
Identities = 16/24 (66%), Positives = 18/24 (75%)
Frame = +1
Query: 184 QMQQVLDAMFGKRSEPGEYVIRQG 255
QM QVLDAMF K + GE+VI QG
Sbjct: 162 QMSQVLDAMFEKLVKDGEHVIDQG 185
>AC006387-1|AAS07389.1| 306|Homo sapiens unknown protein.
Length = 306
Score = 97.9 bits (233), Expect = 2e-20
Identities = 46/80 (57%), Positives = 58/80 (72%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
GDDGDNFYVI+ G FD+ V D V + V Y+ GSFGELALMYN P AA++ + + GA
Sbjct: 185 GDDGDNFYVIDRGTFDIYVKCDG-VGRCVGNYDNRGSFGELALMYNTPRAATITATSPGA 243
Query: 432 LWAMDRHTFRRILLKSAFKK 491
LW +DR TFRRI++K+ KK
Sbjct: 244 LWGLDRVTFRRIIVKNNAKK 263
Score = 58.8 bits (136), Expect = 9e-09
Identities = 29/63 (46%), Positives = 42/63 (66%)
Frame = +2
Query: 8 PPVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAHK 187
P + RF RR SV AE Y+P+E++ D + + PK+D QR RL EA + ILLF++LD +
Sbjct: 104 PVINRFT-RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQ 162
Query: 188 CSR 196
S+
Sbjct: 163 MSQ 165
Score = 33.5 bits (73), Expect = 0.41
Identities = 16/24 (66%), Positives = 18/24 (75%)
Frame = +1
Query: 184 QMQQVLDAMFGKRSEPGEYVIRQG 255
QM QVLDAMF K + GE+VI QG
Sbjct: 162 QMSQVLDAMFEKLVKDGEHVIDQG 185
>M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein
kinase RI-beta regulatory subunit protein.
Length = 380
Score = 79.4 bits (187), Expect = 6e-15
Identities = 41/82 (50%), Positives = 56/82 (68%)
Frame = +3
Query: 246 QTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTA 425
Q G++GDNFYV++ G DV V G E V + EG GSFGELAL+Y P AA+V+++T
Sbjct: 165 QQGNEGDNFYVVDQGEVDVYVNG----EWVTNISEG-GSFGELALIYGTPRAATVKAKTD 219
Query: 426 GALWAMDRHTFRRILLKSAFKK 491
LW +DR ++RRIL+ S +K
Sbjct: 220 LKLWGIDRDSYRRILMGSTLRK 241
Score = 44.8 bits (101), Expect = 2e-04
Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPLAASVRSQTAG 428
G+ GD+FY+I G VL E V V S FGE+AL+ N P AA+V ++
Sbjct: 285 GEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPL 344
Query: 429 ALWAMDRHTFRRIL 470
+DR F R+L
Sbjct: 345 KCVKLDRPRFERVL 358
Score = 31.1 bits (67), Expect = 2.2
Identities = 21/61 (34%), Positives = 29/61 (47%)
Frame = +2
Query: 11 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAHKC 190
PV + RR V AE Y E+D+ V PK LA+A+ +LF LD ++
Sbjct: 88 PVVKARRRRGGVSAEVYT--EEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNER 145
Query: 191 S 193
S
Sbjct: 146 S 146
>BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, beta protein.
Length = 381
Score = 79.4 bits (187), Expect = 6e-15
Identities = 41/82 (50%), Positives = 56/82 (68%)
Frame = +3
Query: 246 QTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTA 425
Q G++GDNFYV++ G DV V G E V + EG GSFGELAL+Y P AA+V+++T
Sbjct: 166 QQGNEGDNFYVVDQGEVDVYVNG----EWVTNISEG-GSFGELALIYGTPRAATVKAKTD 220
Query: 426 GALWAMDRHTFRRILLKSAFKK 491
LW +DR ++RRIL+ S +K
Sbjct: 221 LKLWGIDRDSYRRILMGSTLRK 242
Score = 44.8 bits (101), Expect = 2e-04
Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPLAASVRSQTAG 428
G+ GD+FY+I G VL E V V S FGE+AL+ N P AA+V ++
Sbjct: 286 GEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPL 345
Query: 429 ALWAMDRHTFRRIL 470
+DR F R+L
Sbjct: 346 KCVKLDRPRFERVL 359
Score = 31.1 bits (67), Expect = 2.2
Identities = 21/61 (34%), Positives = 29/61 (47%)
Frame = +2
Query: 11 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAHKC 190
PV + RR V AE Y E+D+ V PK LA+A+ +LF LD ++
Sbjct: 89 PVVKARRRRGGVSAEVYT--EEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNER 146
Query: 191 S 193
S
Sbjct: 147 S 147
>BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein.
Length = 381
Score = 79.4 bits (187), Expect = 6e-15
Identities = 41/82 (50%), Positives = 56/82 (68%)
Frame = +3
Query: 246 QTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTA 425
Q G++GDNFYV++ G DV V G E V + EG GSFGELAL+Y P AA+V+++T
Sbjct: 166 QQGNEGDNFYVVDQGEVDVYVNG----EWVTNISEG-GSFGELALIYGTPRAATVKAKTD 220
Query: 426 GALWAMDRHTFRRILLKSAFKK 491
LW +DR ++RRIL+ S +K
Sbjct: 221 LKLWGIDRDSYRRILMGSTLRK 242
Score = 44.8 bits (101), Expect = 2e-04
Identities = 28/74 (37%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPLAASVRSQTAG 428
G+ GD+FY+I G VL E V V S FGE+AL+ N P AA+V ++
Sbjct: 286 GEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPL 345
Query: 429 ALWAMDRHTFRRIL 470
+DR F R+L
Sbjct: 346 KCVKLDRPRFERVL 359
Score = 31.1 bits (67), Expect = 2.2
Identities = 21/61 (34%), Positives = 29/61 (47%)
Frame = +2
Query: 11 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAHKC 190
PV + RR V AE Y E+D+ V PK LA+A+ +LF LD ++
Sbjct: 89 PVVKARRRRGGVSAEVYT--EEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNER 146
Query: 191 S 193
S
Sbjct: 147 S 147
>M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein
kinase type I-alpha subunit protein.
Length = 381
Score = 77.0 bits (181), Expect = 3e-14
Identities = 41/82 (50%), Positives = 53/82 (64%)
Frame = +3
Query: 246 QTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTA 425
Q GD+GDNFYVI+ G DV V E EG GSFGELAL+Y P AA+V+++T
Sbjct: 166 QQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFGELALIYGTPRAATVKAKTN 220
Query: 426 GALWAMDRHTFRRILLKSAFKK 491
LW +DR ++RRIL+ S +K
Sbjct: 221 VKLWGIDRDSYRRILMGSTLRK 242
Score = 41.1 bits (92), Expect = 0.002
Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPLAASVRSQTAG 428
G+ GD F++I G VL + E V V S FGE+AL+ N P AA+V ++
Sbjct: 286 GEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPL 345
Query: 429 ALWAMDRHTFRRIL 470
+DR F R+L
Sbjct: 346 KCVKLDRPRFERVL 359
Score = 33.1 bits (72), Expect = 0.54
Identities = 21/61 (34%), Positives = 31/61 (50%)
Frame = +2
Query: 11 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAHKC 190
PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD ++
Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146
Query: 191 S 193
S
Sbjct: 147 S 147
>M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein
kinase regulatory subunit type 1 protein.
Length = 381
Score = 77.0 bits (181), Expect = 3e-14
Identities = 41/82 (50%), Positives = 53/82 (64%)
Frame = +3
Query: 246 QTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTA 425
Q GD+GDNFYVI+ G DV V E EG GSFGELAL+Y P AA+V+++T
Sbjct: 166 QQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFGELALIYGTPRAATVKAKTN 220
Query: 426 GALWAMDRHTFRRILLKSAFKK 491
LW +DR ++RRIL+ S +K
Sbjct: 221 VKLWGIDRDSYRRILMGSTLRK 242
Score = 41.1 bits (92), Expect = 0.002
Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPLAASVRSQTAG 428
G+ GD F++I G VL + E V V S FGE+AL+ N P AA+V ++
Sbjct: 286 GEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPL 345
Query: 429 ALWAMDRHTFRRIL 470
+DR F R+L
Sbjct: 346 KCVKLDRPRFERVL 359
Score = 33.1 bits (72), Expect = 0.54
Identities = 21/61 (34%), Positives = 31/61 (50%)
Frame = +2
Query: 11 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAHKC 190
PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD ++
Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146
Query: 191 S 193
S
Sbjct: 147 S 147
>BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 77.0 bits (181), Expect = 3e-14
Identities = 41/82 (50%), Positives = 53/82 (64%)
Frame = +3
Query: 246 QTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTA 425
Q GD+GDNFYVI+ G DV V E EG GSFGELAL+Y P AA+V+++T
Sbjct: 166 QQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFGELALIYGTPRAATVKAKTN 220
Query: 426 GALWAMDRHTFRRILLKSAFKK 491
LW +DR ++RRIL+ S +K
Sbjct: 221 VKLWGIDRDSYRRILMGSTLRK 242
Score = 41.1 bits (92), Expect = 0.002
Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPLAASVRSQTAG 428
G+ GD F++I G VL + E V V S FGE+AL+ N P AA+V ++
Sbjct: 286 GEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPL 345
Query: 429 ALWAMDRHTFRRIL 470
+DR F R+L
Sbjct: 346 KCVKLDRPRFERVL 359
Score = 33.1 bits (72), Expect = 0.54
Identities = 21/61 (34%), Positives = 31/61 (50%)
Frame = +2
Query: 11 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAHKC 190
PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD ++
Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146
Query: 191 S 193
S
Sbjct: 147 S 147
>BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 77.0 bits (181), Expect = 3e-14
Identities = 41/82 (50%), Positives = 53/82 (64%)
Frame = +3
Query: 246 QTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTA 425
Q GD+GDNFYVI+ G DV V E EG GSFGELAL+Y P AA+V+++T
Sbjct: 166 QQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFGELALIYGTPRAATVKAKTN 220
Query: 426 GALWAMDRHTFRRILLKSAFKK 491
LW +DR ++RRIL+ S +K
Sbjct: 221 VKLWGIDRDSYRRILMGSTLRK 242
Score = 41.1 bits (92), Expect = 0.002
Identities = 27/74 (36%), Positives = 38/74 (51%), Gaps = 1/74 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKV-VHTYEGSGSFGELALMYNMPLAASVRSQTAG 428
G+ GD F++I G VL + E V V S FGE+AL+ N P AA+V ++
Sbjct: 286 GEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPL 345
Query: 429 ALWAMDRHTFRRIL 470
+DR F R+L
Sbjct: 346 KCVKLDRPRFERVL 359
Score = 33.1 bits (72), Expect = 0.54
Identities = 21/61 (34%), Positives = 31/61 (50%)
Frame = +2
Query: 11 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAHKC 190
PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD ++
Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146
Query: 191 S 193
S
Sbjct: 147 S 147
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 73.7 bits (173), Expect = 3e-13
Identities = 39/77 (50%), Positives = 51/77 (66%)
Frame = +3
Query: 246 QTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTA 425
Q GD+GDNFYVI+ G DV V E EG GSFGELAL+Y P AA+V+++T
Sbjct: 166 QQGDEGDNFYVIDQGETDVYVNN----EWATSVGEG-GSFGELALIYGTPRAATVKAKTN 220
Query: 426 GALWAMDRHTFRRILLK 476
LW +DR ++RRIL++
Sbjct: 221 VKLWGIDRDSYRRILME 237
Score = 33.1 bits (72), Expect = 0.54
Identities = 21/61 (34%), Positives = 31/61 (50%)
Frame = +2
Query: 11 PVARFNNRRKSVFAETYDPEEDDSDEGAPAVFPKSDAQRARLAEAVRGILLFRSLDAHKC 190
PV + RR ++ AE Y E+D+ V PK A LA+A+ +LF LD ++
Sbjct: 89 PVVKGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNER 146
Query: 191 S 193
S
Sbjct: 147 S 147
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 47.6 bits (108), Expect = 2e-05
Identities = 25/77 (32%), Positives = 45/77 (58%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G+ G++ +V+ G +V + EK++ + +FGELA++YN ASV++ T
Sbjct: 199 GEPGNHIFVLAEGRLEVF-----QGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVK 253
Query: 432 LWAMDRHTFRRILLKSA 482
WA+DR F+ I+ ++A
Sbjct: 254 TWALDREVFQNIMRRTA 270
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 47.6 bits (108), Expect = 2e-05
Identities = 25/77 (32%), Positives = 45/77 (58%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G+ G++ +V+ G +V + EK++ + +FGELA++YN ASV++ T
Sbjct: 199 GEPGNHIFVLAEGRLEVF-----QGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVK 253
Query: 432 LWAMDRHTFRRILLKSA 482
WA+DR F+ I+ ++A
Sbjct: 254 TWALDREVFQNIMRRTA 270
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 47.6 bits (108), Expect = 2e-05
Identities = 25/77 (32%), Positives = 45/77 (58%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G+ G++ +V+ G +V + EK++ + +FGELA++YN ASV++ T
Sbjct: 199 GEPGNHIFVLAEGRLEVF-----QGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVK 253
Query: 432 LWAMDRHTFRRILLKSA 482
WA+DR F+ I+ ++A
Sbjct: 254 TWALDREVFQNIMRRTA 270
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 149 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 202
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 203 KLWAIDRQCFQTIMMRTGLIK 223
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 134 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 187
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 188 KLWAIDRQCFQTIMMRTGLIK 208
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 149 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 202
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 203 KLWAIDRQCFQTIMMRTGLIK 223
>EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein.
Length = 686
Score = 46.0 bits (104), Expect = 7e-05
Identities = 28/80 (35%), Positives = 43/80 (53%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
GD G YV+E+G +V G K+ G FGELA++YN A+V++
Sbjct: 149 GDVGSLVYVMEDGKVEVTKEG----AKLCTMGPGK-VFGELAILYNCTRTATVKTLVNVK 203
Query: 432 LWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 204 LWAIDRQCFQTIMMRTGLIK 223
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 134 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 187
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 188 KLWAIDRQCFQTIMMRTGLIK 208
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 149 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 202
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 203 KLWAIDRQCFQTIMMRTGLIK 223
>BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein.
Length = 312
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 149 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 202
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 203 KLWAIDRQCFQTIMMRTGLIK 223
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 149 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 202
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 203 KLWAIDRQCFQTIMMRTGLIK 223
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 122 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 175
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 176 KLWAIDRQCFQTIMMRTGLIK 196
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 149 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 202
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 203 KLWAIDRQCFQTIMMRTGLIK 223
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 122 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 175
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 176 KLWAIDRQCFQTIMMRTGLIK 196
>AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 7 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 60
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 61 KLWAIDRQCFQTIMMRTGLIK 81
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 149 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 202
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 203 KLWAIDRQCFQTIMMRTGLIK 223
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 122 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 175
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 176 KLWAIDRQCFQTIMMRTGLIK 196
>AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 7 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 60
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 61 KLWAIDRQCFQTIMMRTGLIK 81
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 149 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 202
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 203 KLWAIDRQCFQTIMMRTGLIK 223
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 46.0 bits (104), Expect = 7e-05
Identities = 29/81 (35%), Positives = 43/81 (53%), Gaps = 1/81 (1%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGS-FGELALMYNMPLAASVRSQTAG 428
GD G YV+E+G +V G V G G FGELA++YN A+V++
Sbjct: 122 GDVGSLVYVMEDGKVEVTKEG------VKLCTMGPGKVFGELAILYNCTRTATVKTLVNV 175
Query: 429 ALWAMDRHTFRRILLKSAFKK 491
LWA+DR F+ I++++ K
Sbjct: 176 KLWAIDRQCFQTIMMRTGLIK 196
>AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN
KINASE TYPE II-BETA REGULATORY CHAIN protein.
Length = 112
Score = 39.5 bits (88), Expect = 0.006
Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 7/80 (8%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVT--GDDRVEK-----VVHTYEGSGSFGELALMYNMPLAASV 410
GD D+F+++E+G + + G VE+ + G FGELAL+ N P AAS
Sbjct: 1 GDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQ-YFGELALVTNKPRAASA 59
Query: 411 RSQTAGALWAMDRHTFRRIL 470
+ AMD F R+L
Sbjct: 60 HAIGTVKCLAMDVQAFERLL 79
>AB209681-1|BAD92918.1| 643|Homo sapiens RAP
guanine-nucleotide-exchange factor 4 variant protein.
Length = 643
Score = 37.9 bits (84), Expect = 0.019
Identities = 29/80 (36%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
Frame = +3
Query: 237 VRNQTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASV-- 410
V NQ G++G ++Y+I G +V++ G + VV T FG+LAL+ + P AAS+
Sbjct: 16 VFNQ-GEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVNDAPRAASIVL 70
Query: 411 RSQTAGALWAMDRHTFRRIL 470
R L +D+ F RIL
Sbjct: 71 REDNCHFL-RVDKEDFNRIL 89
>U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor II protein.
Length = 1011
Score = 37.5 bits (83), Expect = 0.025
Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 2/75 (2%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASV--RSQTA 425
G++G ++Y+I G +V++ G + VV T FG+LAL+ + P AAS+ R
Sbjct: 388 GEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNC 443
Query: 426 GALWAMDRHTFRRIL 470
L +D+ F RIL
Sbjct: 444 HFL-RVDKEDFNRIL 457
>BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein.
Length = 867
Score = 37.5 bits (83), Expect = 0.025
Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 2/75 (2%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASV--RSQTA 425
G++G ++Y+I G +V++ G + VV T FG+LAL+ + P AAS+ R
Sbjct: 244 GEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNC 299
Query: 426 GALWAMDRHTFRRIL 470
L +D+ F RIL
Sbjct: 300 HFL-RVDKEDFNRIL 313
>BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 4 protein.
Length = 1011
Score = 37.5 bits (83), Expect = 0.025
Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 2/75 (2%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASV--RSQTA 425
G++G ++Y+I G +V++ G + VV T FG+LAL+ + P AAS+ R
Sbjct: 388 GEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNC 443
Query: 426 GALWAMDRHTFRRIL 470
L +D+ F RIL
Sbjct: 444 HFL-RVDKEDFNRIL 457
>AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein.
Length = 1011
Score = 37.5 bits (83), Expect = 0.025
Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 2/75 (2%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASV--RSQTA 425
G++G ++Y+I G +V++ G + VV T FG+LAL+ + P AAS+ R
Sbjct: 388 GEEGTSWYIILKGSVNVVIYG----KGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNC 443
Query: 426 GALWAMDRHTFRRIL 470
L +D+ F RIL
Sbjct: 444 HFL-RVDKEDFNRIL 457
>BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 34.7 bits (76), Expect = 0.18
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +3
Query: 225 RARRVRNQTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAA 404
+A V GD G ++Y+I G +V+ G V + +EG FG+LAL+ + P AA
Sbjct: 226 KAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTL---HEGD-DFGQLALVNDAPRAA 281
Query: 405 SV--RSQTAGALWAMDRHTFRRIL 470
++ R L +D+ F RI+
Sbjct: 282 TIILREDNCHFL-RVDKQDFNRII 304
>BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein.
Length = 343
Score = 34.7 bits (76), Expect = 0.18
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +3
Query: 225 RARRVRNQTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAA 404
+A V GD G ++Y+I G +V+ G V + +EG FG+LAL+ + P AA
Sbjct: 226 KAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTL---HEGD-DFGQLALVNDAPRAA 281
Query: 405 SV--RSQTAGALWAMDRHTFRRIL 470
++ R L +D+ F RI+
Sbjct: 282 TIILREDNCHFL-RVDKQDFNRII 304
>BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein.
Length = 321
Score = 34.7 bits (76), Expect = 0.18
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +3
Query: 225 RARRVRNQTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAA 404
+A V GD G ++Y+I G +V+ G V + +EG FG+LAL+ + P AA
Sbjct: 226 KAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTL---HEGD-DFGQLALVNDAPRAA 281
Query: 405 SV--RSQTAGALWAMDRHTFRRIL 470
++ R L +D+ F RI+
Sbjct: 282 TIILREDNCHFL-RVDKQDFNRII 304
>BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 34.7 bits (76), Expect = 0.18
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +3
Query: 225 RARRVRNQTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAA 404
+A V GD G ++Y+I G +V+ G V + +EG FG+LAL+ + P AA
Sbjct: 226 KAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTL---HEGD-DFGQLALVNDAPRAA 281
Query: 405 SV--RSQTAGALWAMDRHTFRRIL 470
++ R L +D+ F RI+
Sbjct: 282 TIILREDNCHFL-RVDKQDFNRII 304
>AJ238850-1|CAB52754.1| 1203|Homo sapiens
hyperpolarization-activated channel type 4 protein.
Length = 1203
Score = 34.7 bits (76), Expect = 0.18
Identities = 22/73 (30%), Positives = 34/73 (46%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++GV VL G+ + +Y FGE+ L+ ASVR+ T
Sbjct: 626 GTIGKKMYFIQHGVVSVLTKGNKETKLADGSY-----FGEICLLTRGRRTASVRADTYCR 680
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 681 LYSLSVDNFNEVL 693
>AJ133727-1|CAB42630.1| 889|Homo sapiens
hyperpolarization-activated cyclic nucleotide-gated
channel hHCN2 protein.
Length = 889
Score = 34.7 bits (76), Expect = 0.18
Identities = 24/73 (32%), Positives = 36/73 (49%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++GV VL G+ K + +GS FGE+ L+ ASVR+ T
Sbjct: 575 GTIGKKMYFIQHGVVSVLTKGN----KEMKLSDGS-YFGEICLLTRGRRTASVRADTYCR 629
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 630 LYSLSVDNFNEVL 642
>AJ132429-1|CAB42604.1| 1203|Homo sapiens
hyperpolarization-activated cyclic nucleotide gated
cation channel hHCN4 protein.
Length = 1203
Score = 34.7 bits (76), Expect = 0.18
Identities = 22/73 (30%), Positives = 34/73 (46%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++GV VL G+ + +Y FGE+ L+ ASVR+ T
Sbjct: 626 GTIGKKMYFIQHGVVSVLTKGNKETKLADGSY-----FGEICLLTRGRRTASVRADTYCR 680
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 681 LYSLSVDNFNEVL 693
>AJ012582-1|CAB42602.1| 889|Homo sapiens
hyperpolarization-activated cation channel HCN2 protein.
Length = 889
Score = 34.7 bits (76), Expect = 0.18
Identities = 24/73 (32%), Positives = 36/73 (49%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++GV VL G+ K + +GS FGE+ L+ ASVR+ T
Sbjct: 575 GTIGKKMYFIQHGVVSVLTKGN----KEMKLSDGS-YFGEICLLTRGRRTASVRADTYCR 629
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 630 LYSLSVDNFNEVL 642
>AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide
exchange factor protein.
Length = 881
Score = 34.7 bits (76), Expect = 0.18
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 2/84 (2%)
Frame = +3
Query: 225 RARRVRNQTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAA 404
+A V GD G ++Y+I G +V+ G V + +EG FG+LAL+ + P AA
Sbjct: 226 KAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTL---HEGD-DFGQLALVNDAPRAA 281
Query: 405 SV--RSQTAGALWAMDRHTFRRIL 470
++ R L +D+ F RI+
Sbjct: 282 TIILREDNCHFL-RVDKQDFNRII 304
>AF065164-1|AAC28444.2| 889|Homo sapiens
hyperpolarization-activated, cyclic nucleotide-gated
channel 2 protein.
Length = 889
Score = 34.7 bits (76), Expect = 0.18
Identities = 24/73 (32%), Positives = 36/73 (49%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++GV VL G+ K + +GS FGE+ L+ ASVR+ T
Sbjct: 575 GTIGKKMYFIQHGVVSVLTKGN----KEMKLSDGS-YFGEICLLTRGRRTASVRADTYCR 629
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 630 LYSLSVDNFNEVL 642
>AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2
protein.
Length = 597
Score = 34.7 bits (76), Expect = 0.18
Identities = 24/73 (32%), Positives = 36/73 (49%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++GV VL G+ K + +GS FGE+ L+ ASVR+ T
Sbjct: 429 GTIGKKMYFIQHGVVSVLTKGN----KEMKLSDGS-YFGEICLLTRGRRTASVRADTYCR 483
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 484 LYSLSVDNFNEVL 496
>U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 556
Score = 34.3 bits (75), Expect = 0.23
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +3
Query: 225 RARRVRNQTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAA 404
+A V GD G ++Y+I G +V+ G V + +EG FG+LAL+ + P AA
Sbjct: 226 KAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTL---HEGD-DFGQLALVNDAPRAA 281
Query: 405 SVRSQTAGA-LWAMDRHTFRRIL 470
++ + +D+ F RI+
Sbjct: 282 TIILREYNCHFLRVDKQDFNRII 304
>U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 881
Score = 34.3 bits (75), Expect = 0.23
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +3
Query: 225 RARRVRNQTGDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAA 404
+A V GD G ++Y+I G +V+ G V + +EG FG+LAL+ + P AA
Sbjct: 226 KAGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTL---HEGD-DFGQLALVNDAPRAA 281
Query: 405 SVRSQTAGA-LWAMDRHTFRRIL 470
++ + +D+ F RI+
Sbjct: 282 TIILREYNCHFLRVDKQDFNRII 304
>EF157730-1|ABO15447.1| 35|Homo sapiens type II cAMP-dependent
regulatory protein kinase beta protein.
Length = 35
Score = 33.5 bits (73), Expect = 0.41
Identities = 16/24 (66%), Positives = 18/24 (75%)
Frame = +1
Query: 184 QMQQVLDAMFGKRSEPGEYVIRQG 255
QM QVLDAMF K + GE+VI QG
Sbjct: 2 QMSQVLDAMFEKLVKDGEHVIDQG 25
>AB029009-1|BAA83038.1| 902|Homo sapiens KIAA1086 protein protein.
Length = 902
Score = 31.1 bits (67), Expect = 2.2
Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 3/71 (4%)
Frame = -2
Query: 233 PGSDLFPNI-ASRTCCICARQENGTAVCPGPPQRDGLSVRPTWG--TRQGLLRQNHPLRG 63
P S P++ AS + R A+C GPP+ RP WG + L P +G
Sbjct: 339 PTSPTGPSVCASSRPALAKRPVASKALCEGPPEPQAAGCRPQWGKPAQPKLEGPGAPTQG 398
Query: 62 HKSRRKRICAD 30
C+D
Sbjct: 399 GSKEAPAGCSD 409
>AB013004-1|BAA36573.1| 87|Homo sapiens CD22 protein.
Length = 87
Score = 31.1 bits (67), Expect = 2.2
Identities = 15/39 (38%), Positives = 20/39 (51%)
Frame = +3
Query: 90 EPLPCSPSRTHREPVSLRRSGAYCCSVLLTRTNAAGSGC 206
+ LP + EPV ++ SGAY C TN+ G GC
Sbjct: 44 QSLPYHSQKLRLEPVKVQHSGAYWCQ----GTNSVGKGC 78
>BC036847-1|AAH36847.1| 272|Homo sapiens neurogenin 2 protein.
Length = 272
Score = 30.7 bits (66), Expect = 2.9
Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Frame = -3
Query: 376 ASSPNEPEPSYVW--TTFSTRSSPVTRTSKTPFSMT*KLSPSSP 251
+SS + P P+ W T SS V+ S +P+S T LSP+SP
Sbjct: 202 SSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCT--LSPASP 243
>AF303002-1|AAG40770.1| 250|Homo sapiens neurogenin 2 protein.
Length = 250
Score = 30.7 bits (66), Expect = 2.9
Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Frame = -3
Query: 376 ASSPNEPEPSYVW--TTFSTRSSPVTRTSKTPFSMT*KLSPSSP 251
+SS + P P+ W T SS V+ S +P+S T LSP+SP
Sbjct: 180 SSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCT--LSPASP 221
>BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein.
Length = 450
Score = 30.3 bits (65), Expect = 3.8
Identities = 22/73 (30%), Positives = 34/73 (46%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++G+ VL G + +GS FGE+ L+ ASVR+ T
Sbjct: 135 GSVGRKMYFIQHGLLSVLARG----ARDTRLTDGS-YFGEICLLTRGRRTASVRADTYCR 189
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 190 LYSLSVDHFNAVL 202
>BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for
IMAGE:3507934) protein.
Length = 571
Score = 30.3 bits (65), Expect = 3.8
Identities = 22/73 (30%), Positives = 34/73 (46%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++G+ VL G + +GS FGE+ L+ ASVR+ T
Sbjct: 256 GSVGRKMYFIQHGLLSVLARG----ARDTRLTDGS-YFGEICLLTRGRRTASVRADTYCR 310
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 311 LYSLSVDHFNAVL 323
>AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel 3
protein.
Length = 774
Score = 30.3 bits (65), Expect = 3.8
Identities = 22/73 (30%), Positives = 34/73 (46%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++G+ VL G + +GS FGE+ L+ ASVR+ T
Sbjct: 459 GSVGRKMYFIQHGLLSVLARG----ARDTRLTDGS-YFGEICLLTRGRRTASVRADTYCR 513
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 514 LYSLSVDHFNAVL 526
>AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 774
Score = 30.3 bits (65), Expect = 3.8
Identities = 22/73 (30%), Positives = 34/73 (46%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++G+ VL G + +GS FGE+ L+ ASVR+ T
Sbjct: 459 GSVGRKMYFIQHGLLSVLARG----ARDTRLTDGS-YFGEICLLTRGRRTASVRADTYCR 513
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 514 LYSLSVDHFNAVL 526
>AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1
protein.
Length = 749
Score = 30.3 bits (65), Expect = 3.8
Identities = 20/73 (27%), Positives = 33/73 (45%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++GV V+ ++ +Y FGE+ L+ ASVR+ T
Sbjct: 385 GAVGKKMYFIQHGVAGVITKSSKEMKLTDGSY-----FGEICLLTKGRRTASVRADTYCR 439
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 440 LYSLSVDNFNEVL 452
>AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein.
Length = 711
Score = 30.3 bits (65), Expect = 3.8
Identities = 22/73 (30%), Positives = 34/73 (46%)
Frame = +3
Query: 252 GDDGDNFYVIENGVFDVLVTGDDRVEKVVHTYEGSGSFGELALMYNMPLAASVRSQTAGA 431
G G Y I++G+ VL G + +GS FGE+ L+ ASVR+ T
Sbjct: 396 GSVGRKMYFIQHGLLSVLARG----ARDTRLTDGS-YFGEICLLTRGRRTASVRADTYCR 450
Query: 432 LWAMDRHTFRRIL 470
L+++ F +L
Sbjct: 451 LYSLSVDHFNAVL 463
>AK097840-1|BAC05181.1| 452|Homo sapiens protein ( Homo sapiens
cDNA FLJ40521 fis, clone TESTI2046797. ).
Length = 452
Score = 29.9 bits (64), Expect = 5.0
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 4/73 (5%)
Frame = +3
Query: 48 SPRLMTPKRMILTKEPLPCSPS-RTHREPVSLR---RSGAYCCSVLLTRTNAAGSGCDVR 215
SPR TP+ ++ P + +EP R R+GA + + + N GC ++
Sbjct: 27 SPRTGTPRTTAVSSNRDPKNDGCLLKQEPRGRRLSPRTGAPGTTAVSSNRNPEDDGCLLK 86
Query: 216 KEIRARRVRNQTG 254
+E R RR+ QTG
Sbjct: 87 QEPRGRRLSPQTG 99
>BC040640-1|AAH40640.1| 802|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 19 protein.
Length = 802
Score = 29.5 bits (63), Expect = 6.6
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = +1
Query: 397 WQHLYGPRPPALCGPWT 447
W H G +PPAL GPW+
Sbjct: 102 WPHCPGAQPPALEGPWS 118
>BC012982-1|AAH12982.1| 706|Homo sapiens ARHGEF19 protein protein.
Length = 706
Score = 29.5 bits (63), Expect = 6.6
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = +1
Query: 397 WQHLYGPRPPALCGPWT 447
W H G +PPAL GPW+
Sbjct: 6 WPHCPGAQPPALEGPWS 22
>AL109627-9|CAI22567.1| 502|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 19 protein.
Length = 502
Score = 29.5 bits (63), Expect = 6.6
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = +1
Query: 397 WQHLYGPRPPALCGPWT 447
W H G +PPAL GPW+
Sbjct: 102 WPHCPGAQPPALEGPWS 118
>AL109627-8|CAI22566.1| 802|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 19 protein.
Length = 802
Score = 29.5 bits (63), Expect = 6.6
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = +1
Query: 397 WQHLYGPRPPALCGPWT 447
W H G +PPAL GPW+
Sbjct: 102 WPHCPGAQPPALEGPWS 118
>AK091281-1|BAC03627.1| 502|Homo sapiens protein ( Homo sapiens
cDNA FLJ33962 fis, clone CTONG2018900, moderately
similar to PROBABLE GUANINE NUCLEOTIDE REGULATORY
PROTEIN TIM. ).
Length = 502
Score = 29.5 bits (63), Expect = 6.6
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = +1
Query: 397 WQHLYGPRPPALCGPWT 447
W H G +PPAL GPW+
Sbjct: 102 WPHCPGAQPPALEGPWS 118
>AL590007-1|CAI12790.2| 3169|Homo sapiens FRAS1 related
extracellular matrix protein 2 protein.
Length = 3169
Score = 29.1 bits (62), Expect = 8.8
Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 3/52 (5%)
Frame = -3
Query: 460 RNVWR---SMAHRAPAVWDRTDAASGMLYIRASSPNEPEPSYVWTTFSTRSS 314
R +WR + R W + D G L+ R S P+ P P TF + +
Sbjct: 626 RGLWRKEGAFYERTVTEWQQQDITEGRLFYRHSGPHSPGPVTDQFTFRVQDN 677
>AL354819-1|CAI16761.2| 3169|Homo sapiens FRAS1 related
extracellular matrix protein 2 protein.
Length = 3169
Score = 29.1 bits (62), Expect = 8.8
Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 3/52 (5%)
Frame = -3
Query: 460 RNVWR---SMAHRAPAVWDRTDAASGMLYIRASSPNEPEPSYVWTTFSTRSS 314
R +WR + R W + D G L+ R S P+ P P TF + +
Sbjct: 626 RGLWRKEGAFYERTVTEWQQQDITEGRLFYRHSGPHSPGPVTDQFTFRVQDN 677
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 75,058,893
Number of Sequences: 237096
Number of extensions: 1662137
Number of successful extensions: 9915
Number of sequences better than 10.0: 72
Number of HSP's better than 10.0 without gapping: 9442
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9886
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4423060356
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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