Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= pg--0398.Seq
(760 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3 (im... 105 2e-22
BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3 (im... 105 2e-22
BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3 (im... 105 2e-22
AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3 (im... 105 2e-22
AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3 (im... 105 2e-22
AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 var... 105 2e-22
AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subuni... 105 2e-22
D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein. 104 3e-22
Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein. 103 5e-22
AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog ... 103 5e-22
U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein. 101 4e-21
BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4 (im... 101 4e-21
BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4 (im... 101 4e-21
AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein. 101 4e-21
U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein. 81 4e-15
U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein. 81 4e-15
BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RA... 81 4e-15
BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RA... 81 4e-15
BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RA... 81 4e-15
AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2 pro... 81 4e-15
BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RA... 79 2e-14
BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6 (im... 69 2e-11
BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6 (im... 69 2e-11
AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6 (im... 69 2e-11
AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6 (im... 69 2e-11
AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subuni... 69 2e-11
CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein. 66 1e-10
BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1 (im... 66 1e-10
BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1 (im... 66 1e-10
BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1 (im... 66 1e-10
BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1 (im... 66 1e-10
BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5 (im... 66 1e-10
AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5 (im... 66 1e-10
AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein. 66 1e-10
S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor ... 64 7e-10
AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5 (im... 50 7e-06
CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein. 36 0.16
BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antige... 36 0.16
AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antige... 36 0.16
AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antige... 36 0.16
AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antig... 36 0.16
AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antig... 36 0.16
AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein... 36 0.16
AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antige... 35 0.28
AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antig... 35 0.28
AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6 (im... 35 0.37
AL513128-2|CAH72208.1| 191|Homo sapiens sperm associated antige... 34 0.48
AL158211-13|CAI15961.1| 191|Homo sapiens sperm associated antig... 34 0.48
Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein. 32 2.0
M82962-1|AAA21338.1| 746|Homo sapiens N-benzoyl-L-tyrosyl-p-ami... 31 4.5
BC131714-1|AAI31715.1| 746|Homo sapiens meprin A, alpha (PABA p... 31 4.5
AL161618-1|CAC21508.1| 746|Homo sapiens meprin A, alpha (PABA p... 31 4.5
AF478685-1|AAL85339.1| 746|Homo sapiens N-benzoyl-L-tyrosyl-p-a... 31 4.5
BC111961-1|AAI11962.1| 387|Homo sapiens hypothetical protein LO... 30 7.9
BC111959-1|AAI11960.1| 387|Homo sapiens hypothetical protein FL... 30 7.9
AK098667-1|BAC05372.1| 387|Homo sapiens protein ( Homo sapiens ... 30 7.9
>BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 105 bits (251), Expect = 2e-22
Identities = 66/162 (40%), Positives = 94/162 (58%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLD-ELVMNAANAENPEAQLAA 439
VTVELRKNKR+E L K+RNVP S ++ ++D + ++ E ++ A ++NP QL+A
Sbjct: 32 VTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSA 91
Query: 440 VQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERLH 610
VQ RKLLS D+NPPID+LI +G P ++Q ++ L T +
Sbjct: 92 VQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWAL----TNIASGTS 147
Query: 611 KQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGP 733
QT+ + + F + +NVC+QAVWALGNIIGDGP
Sbjct: 148 AQTQDIVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Score = 89.8 bits (213), Expect = 9e-18
Identities = 41/57 (71%), Positives = 48/57 (84%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV+CL R DNP+LQFE AWALTNIASGTSAQT +V + AVP+FL+LL S H+
Sbjct: 115 ILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQDIVQSNAVPLFLRLLRSPHQ 171
>BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 105 bits (251), Expect = 2e-22
Identities = 66/162 (40%), Positives = 94/162 (58%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLD-ELVMNAANAENPEAQLAA 439
VTVELRKNKR+E L K+RNVP S ++ ++D + ++ E ++ A ++NP QL+A
Sbjct: 32 VTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSA 91
Query: 440 VQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERLH 610
VQ RKLLS D+NPPID+LI +G P ++Q ++ L T +
Sbjct: 92 VQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWAL----TNIASGTS 147
Query: 611 KQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGP 733
QT+ + + F + +NVC+QAVWALGNIIGDGP
Sbjct: 148 AQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Score = 90.2 bits (214), Expect = 7e-18
Identities = 42/57 (73%), Positives = 48/57 (84%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV+CL R DNP+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
>BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 105 bits (251), Expect = 2e-22
Identities = 66/162 (40%), Positives = 94/162 (58%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLD-ELVMNAANAENPEAQLAA 439
VTVELRKNKR+E L K+RNVP S ++ ++D + ++ E ++ A ++NP QL+A
Sbjct: 32 VTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSA 91
Query: 440 VQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERLH 610
VQ RKLLS D+NPPID+LI +G P ++Q ++ L T +
Sbjct: 92 VQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWAL----TNIASGTS 147
Query: 611 KQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGP 733
QT+ + + F + +NVC+QAVWALGNIIGDGP
Sbjct: 148 AQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Score = 90.2 bits (214), Expect = 7e-18
Identities = 42/57 (73%), Positives = 48/57 (84%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV+CL R DNP+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
>AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 105 bits (251), Expect = 2e-22
Identities = 66/162 (40%), Positives = 94/162 (58%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLD-ELVMNAANAENPEAQLAA 439
VTVELRKNKR+E L K+RNVP S ++ ++D + ++ E ++ A ++NP QL+A
Sbjct: 32 VTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSA 91
Query: 440 VQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERLH 610
VQ RKLLS D+NPPID+LI +G P ++Q ++ L T +
Sbjct: 92 VQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWAL----TNIASGTS 147
Query: 611 KQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGP 733
QT+ + + F + +NVC+QAVWALGNIIGDGP
Sbjct: 148 AQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Score = 90.2 bits (214), Expect = 7e-18
Identities = 42/57 (73%), Positives = 48/57 (84%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV+CL R DNP+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
>AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 105 bits (251), Expect = 2e-22
Identities = 66/162 (40%), Positives = 94/162 (58%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLD-ELVMNAANAENPEAQLAA 439
VTVELRKNKR+E L K+RNVP S ++ ++D + ++ E ++ A ++NP QL+A
Sbjct: 32 VTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSA 91
Query: 440 VQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERLH 610
VQ RKLLS D+NPPID+LI +G P ++Q ++ L T +
Sbjct: 92 VQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWAL----TNIASGTS 147
Query: 611 KQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGP 733
QT+ + + F + +NVC+QAVWALGNIIGDGP
Sbjct: 148 AQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Score = 90.2 bits (214), Expect = 7e-18
Identities = 42/57 (73%), Positives = 48/57 (84%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV+CL R DNP+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
>AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3
variant protein.
Length = 521
Score = 105 bits (251), Expect = 2e-22
Identities = 66/162 (40%), Positives = 94/162 (58%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLD-ELVMNAANAENPEAQLAA 439
VTVELRKNKR+E L K+RNVP S ++ ++D + ++ E ++ A ++NP QL+A
Sbjct: 32 VTVELRKNKRDEHLLKKRNVPQEKSLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSA 91
Query: 440 VQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERLH 610
VQ RKLLS D+NPPID+LI +G P ++Q ++ L T +
Sbjct: 92 VQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWAL----TNIASGTS 147
Query: 611 KQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGP 733
QT+ + + F + +NVC+QAVWALGNIIGDGP
Sbjct: 148 AQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Score = 90.2 bits (214), Expect = 7e-18
Identities = 42/57 (73%), Positives = 48/57 (84%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV+CL R DNP+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
>AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subunit
protein.
Length = 521
Score = 105 bits (251), Expect = 2e-22
Identities = 66/162 (40%), Positives = 94/162 (58%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLD-ELVMNAANAENPEAQLAA 439
VTVELRKNKR+E L K+RNVP S ++ ++D + ++ E ++ A ++NP QL+A
Sbjct: 32 VTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSA 91
Query: 440 VQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERLH 610
VQ RKLLS D+NPPID+LI +G P ++Q ++ L T +
Sbjct: 92 VQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWAL----TNIASGTS 147
Query: 611 KQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGP 733
QT+ + + F + +NVC+QAVWALGNIIGDGP
Sbjct: 148 AQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Score = 90.2 bits (214), Expect = 7e-18
Identities = 42/57 (73%), Positives = 48/57 (84%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV+CL R DNP+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
>D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein.
Length = 521
Score = 104 bits (250), Expect = 3e-22
Identities = 66/162 (40%), Positives = 94/162 (58%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLD-ELVMNAANAENPEAQLAA 439
VTVELRKNKR+E L K+RNVP S ++ ++D + ++ E ++ A ++NP QL+A
Sbjct: 32 VTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSA 91
Query: 440 VQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERLH 610
VQ RKLLS D+NPPID+LI +G P ++Q ++ L T +
Sbjct: 92 VQAARKLLSSDQNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWAL----TNIASGTS 147
Query: 611 KQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGP 733
QT+ + + F + +NVC+QAVWALGNIIGDGP
Sbjct: 148 AQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Score = 90.2 bits (214), Expect = 7e-18
Identities = 42/57 (73%), Positives = 48/57 (84%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV+CL R DNP+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
>Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein.
Length = 521
Score = 103 bits (248), Expect = 5e-22
Identities = 65/162 (40%), Positives = 94/162 (58%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLD-ELVMNAANAENPEAQLAA 439
VT+ELRKNKR+E L K+RNVP S ++ ++D + ++ E ++ A ++NP QL+A
Sbjct: 32 VTMELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSA 91
Query: 440 VQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERLH 610
VQ RKLLS D+NPPID+LI +G P ++Q ++ L T +
Sbjct: 92 VQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWAL----TNIASGTS 147
Query: 611 KQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGP 733
QT+ + + F + +NVC+QAVWALGNIIGDGP
Sbjct: 148 AQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Score = 90.2 bits (214), Expect = 7e-18
Identities = 42/57 (73%), Positives = 48/57 (84%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV+CL R DNP+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
>AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog
protein.
Length = 521
Score = 103 bits (248), Expect = 5e-22
Identities = 65/161 (40%), Positives = 92/161 (57%), Gaps = 4/161 (2%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLD-ELVMNAANAENPEAQLAA 439
VTVELRKNKR+E L K+RNVP S ++ ++D + ++ E ++ A ++NP QL+A
Sbjct: 32 VTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSA 91
Query: 440 VQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERLH 610
VQ RKLLS D+NPPID+LI +G P ++Q ++ L + +
Sbjct: 92 VQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQ 151
Query: 611 KQTK*SMPVQYLYSFSS*CQLMKNVCDQAVWALGNIIGDGP 733
+ + +L S Q NVC+QAVWALGNIIGDGP
Sbjct: 152 AVGQSNAVPLFLRLLRSPHQ---NVCEQAVWALGNIIGDGP 189
Score = 87.4 bits (207), Expect = 5e-17
Identities = 41/57 (71%), Positives = 47/57 (82%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV+CL R DNP+LQFE AWALTNIASGTSAQT V + AVP+FL+LL S H+
Sbjct: 115 ILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVGQSNAVPLFLRLLRSPHQ 171
>U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein.
Length = 521
Score = 101 bits (241), Expect = 4e-21
Identities = 68/162 (41%), Positives = 93/162 (57%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LATTDLDELVMNAANAENPEAQLA 436
V VELRKNKR+E L KRRNVP ++ +ID + + T L+ +V NA++ +N QL+
Sbjct: 32 VVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQNASS-DNQGIQLS 90
Query: 437 AVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERL 607
AVQ RKLLS D+NPPID+LI +G P ++Q ++ L + E+
Sbjct: 91 AVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQT 150
Query: 608 HKQTK*SMPVQYLYSFSS*CQLMKNVCDQAVWALGNIIGDGP 733
+ + +L S Q NVC+QAVWALGNIIGDGP
Sbjct: 151 QAVVQSNAVPLFLRLLHSPHQ---NVCEQAVWALGNIIGDGP 189
Score = 87.4 bits (207), Expect = 5e-17
Identities = 41/57 (71%), Positives = 46/57 (80%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV CL R DNP+LQFE AWALTNIASGTS QT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQ 171
Score = 32.3 bits (70), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +1
Query: 565 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
E W L+NI +G Q V+ A VP+ + LL
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLL 377
>BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 101 bits (241), Expect = 4e-21
Identities = 68/162 (41%), Positives = 93/162 (57%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LATTDLDELVMNAANAENPEAQLA 436
V VELRKNKR+E L KRRNVP ++ +ID + + T L+ +V NA++ +N QL+
Sbjct: 32 VVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQNASS-DNQGIQLS 90
Query: 437 AVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERL 607
AVQ RKLLS D+NPPID+LI +G P ++Q ++ L + E+
Sbjct: 91 AVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQT 150
Query: 608 HKQTK*SMPVQYLYSFSS*CQLMKNVCDQAVWALGNIIGDGP 733
+ + +L S Q NVC+QAVWALGNIIGDGP
Sbjct: 151 QAVVQSNAVPLFLRLLHSPHQ---NVCEQAVWALGNIIGDGP 189
Score = 87.4 bits (207), Expect = 5e-17
Identities = 41/57 (71%), Positives = 46/57 (80%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV CL R DNP+LQFE AWALTNIASGTS QT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQ 171
Score = 32.3 bits (70), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +1
Query: 565 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
E W L+NI +G Q V+ A VP+ + LL
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLL 377
>BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 101 bits (241), Expect = 4e-21
Identities = 68/162 (41%), Positives = 93/162 (57%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LATTDLDELVMNAANAENPEAQLA 436
V VELRKNKR+E L KRRNVP ++ +ID + + T L+ +V NA++ +N QL+
Sbjct: 32 VVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQNASS-DNQGIQLS 90
Query: 437 AVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERL 607
AVQ RKLLS D+NPPID+LI +G P ++Q ++ L + E+
Sbjct: 91 AVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQT 150
Query: 608 HKQTK*SMPVQYLYSFSS*CQLMKNVCDQAVWALGNIIGDGP 733
+ + +L S Q NVC+QAVWALGNIIGDGP
Sbjct: 151 QAVVQSNAVPLFLRLLHSPHQ---NVCEQAVWALGNIIGDGP 189
Score = 87.4 bits (207), Expect = 5e-17
Identities = 41/57 (71%), Positives = 46/57 (80%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV CL R DNP+LQFE AWALTNIASGTS QT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQ 171
Score = 32.3 bits (70), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +1
Query: 565 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
E W L+NI +G Q V+ A VP+ + LL
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLL 377
>AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein.
Length = 521
Score = 101 bits (241), Expect = 4e-21
Identities = 68/162 (41%), Positives = 93/162 (57%), Gaps = 5/162 (3%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LATTDLDELVMNAANAENPEAQLA 436
V VELRKNKR+E L KRRNVP ++ +ID + + T L+ +V NA++ +N QL+
Sbjct: 32 VVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQNTSLEAIVQNASS-DNQGIQLS 90
Query: 437 AVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFR---GLTIQRYSSRPLGL*QT*LPERL 607
AVQ RKLLS D+NPPID+LI +G P ++Q ++ L + E+
Sbjct: 91 AVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQT 150
Query: 608 HKQTK*SMPVQYLYSFSS*CQLMKNVCDQAVWALGNIIGDGP 733
+ + +L S Q NVC+QAVWALGNIIGDGP
Sbjct: 151 QAVVQSNAVPLFLRLLHSPHQ---NVCEQAVWALGNIIGDGP 189
Score = 87.4 bits (207), Expect = 5e-17
Identities = 41/57 (71%), Positives = 46/57 (80%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
ILPILV CL R DNP+LQFE AWALTNIASGTS QT VV + AVP+FL+LL S H+
Sbjct: 115 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQ 171
Score = 32.3 bits (70), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +1
Query: 565 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
E W L+NI +G Q V+ A VP+ + LL
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLL 377
>U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein.
Length = 529
Score = 81.0 bits (191), Expect = 4e-15
Identities = 67/173 (38%), Positives = 92/173 (53%), Gaps = 10/173 (5%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLATTD--LDELVMNAANAENPEA 427
V VELRK K+++ + KRRNV P ++ +E N T + +D++V N+ N E
Sbjct: 34 VNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIV-KGINSSNVEN 92
Query: 428 QLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFRGLT----IQRYSSRPLGL*QT*L 595
QL A Q RKLLS +K PPID +I AG P F +F G T IQ S+ L T +
Sbjct: 93 QLQATQAARKLLSREKQPPIDNIIRAGLIPK-FVSFLGRTDCSPIQFESAWAL----TNI 147
Query: 596 PERLHKQTK*SMPVQYLYSF-SS*CQLMKNVCDQAVWALGNIIGDGPVLSRLL 751
+QTK + + +F S ++ +QAVWALGNI GDG V L+
Sbjct: 148 ASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLV 200
Score = 68.9 bits (161), Expect = 2e-11
Identities = 32/56 (57%), Positives = 38/56 (67%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTH 675
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL S H
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPH 175
Score = 38.3 bits (85), Expect = 0.030
Identities = 19/52 (36%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
ILP LV+ L D+P + +T WA++ + G + + VV G VP ++LL
Sbjct: 252 ILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLL 302
Score = 38.3 bits (85), Expect = 0.030
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
++P LV LS+AD Q E WA+TN S GT Q +VH G + + LL + K
Sbjct: 378 LVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
Score = 35.1 bits (77), Expect = 0.28
Identities = 20/52 (38%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
++P LV+ L ++ P + A+ NI +GT QT V+ AGA+ VF LL
Sbjct: 294 VVPQLVKLLGASELPIVT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLL 344
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +3
Query: 165 STDKMATDQAKNRMHVFKNAGKDVDEMRRRGMKSQSS*EKTKE 293
ST++ A A R+H FKN GKD EMRRR ++ K K+
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKK 43
>U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein.
Length = 529
Score = 81.0 bits (191), Expect = 4e-15
Identities = 67/173 (38%), Positives = 92/173 (53%), Gaps = 10/173 (5%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLATTD--LDELVMNAANAENPEA 427
V VELRK K+++ + KRRNV P ++ +E N T + +D++V N+ N E
Sbjct: 34 VNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIV-KGINSSNVEN 92
Query: 428 QLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFRGLT----IQRYSSRPLGL*QT*L 595
QL A Q RKLLS +K PPID +I AG P F +F G T IQ S+ L T +
Sbjct: 93 QLQATQAARKLLSREKQPPIDNIIRAGLIPK-FVSFLGRTDCSPIQFESAWAL----TNI 147
Query: 596 PERLHKQTK*SMPVQYLYSF-SS*CQLMKNVCDQAVWALGNIIGDGPVLSRLL 751
+QTK + + +F S ++ +QAVWALGNI GDG V L+
Sbjct: 148 ASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLV 200
Score = 68.9 bits (161), Expect = 2e-11
Identities = 32/56 (57%), Positives = 38/56 (67%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTH 675
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL S H
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPH 175
Score = 38.3 bits (85), Expect = 0.030
Identities = 19/52 (36%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
ILP LV+ L D+P + +T WA++ + G + + VV G VP ++LL
Sbjct: 252 ILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLL 302
Score = 38.3 bits (85), Expect = 0.030
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
++P LV LS+AD Q E WA+TN S GT Q +VH G + + LL + K
Sbjct: 378 LVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
Score = 35.1 bits (77), Expect = 0.28
Identities = 20/52 (38%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
++P LV+ L ++ P + A+ NI +GT QT V+ AGA+ VF LL
Sbjct: 294 VVPQLVKLLGASELPIVT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLL 344
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +3
Query: 165 STDKMATDQAKNRMHVFKNAGKDVDEMRRRGMKSQSS*EKTKE 293
ST++ A A R+H FKN GKD EMRRR ++ K K+
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKK 43
>BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 81.0 bits (191), Expect = 4e-15
Identities = 67/173 (38%), Positives = 92/173 (53%), Gaps = 10/173 (5%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLATTD--LDELVMNAANAENPEA 427
V VELRK K+++ + KRRNV P ++ +E N T + +D++V N+ N E
Sbjct: 34 VNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIV-KGINSSNVEN 92
Query: 428 QLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFRGLT----IQRYSSRPLGL*QT*L 595
QL A Q RKLLS +K PPID +I AG P F +F G T IQ S+ L T +
Sbjct: 93 QLQATQAARKLLSREKQPPIDNIIRAGLIPK-FVSFLGRTDCSPIQFESAWAL----TNI 147
Query: 596 PERLHKQTK*SMPVQYLYSF-SS*CQLMKNVCDQAVWALGNIIGDGPVLSRLL 751
+QTK + + +F S ++ +QAVWALGNI GDG V L+
Sbjct: 148 ASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLV 200
Score = 68.5 bits (160), Expect = 2e-11
Identities = 32/56 (57%), Positives = 38/56 (67%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTH 675
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL S H
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPH 175
Score = 38.3 bits (85), Expect = 0.030
Identities = 19/52 (36%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
ILP LV+ L D+P + +T WA++ + G + + VV G VP ++LL
Sbjct: 252 ILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLL 302
Score = 38.3 bits (85), Expect = 0.030
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
++P LV LS+AD Q E WA+TN S GT Q +VH G + + LL + K
Sbjct: 378 LVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
Score = 35.1 bits (77), Expect = 0.28
Identities = 20/52 (38%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
++P LV+ L ++ P + A+ NI +GT QT V+ AGA+ VF LL
Sbjct: 294 VVPQLVKLLGASELPIVT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLL 344
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +3
Query: 165 STDKMATDQAKNRMHVFKNAGKDVDEMRRRGMKSQSS*EKTKE 293
ST++ A A R+H FKN GKD EMRRR ++ K K+
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKK 43
>BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 81.0 bits (191), Expect = 4e-15
Identities = 67/173 (38%), Positives = 92/173 (53%), Gaps = 10/173 (5%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLATTD--LDELVMNAANAENPEA 427
V VELRK K+++ + KRRNV P ++ +E N T + +D++V N+ N E
Sbjct: 34 VNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIV-KGINSSNVEN 92
Query: 428 QLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFRGLT----IQRYSSRPLGL*QT*L 595
QL A Q RKLLS +K PPID +I AG P F +F G T IQ S+ L T +
Sbjct: 93 QLQATQAARKLLSREKQPPIDNIIRAGLIPK-FVSFLGRTDCSPIQFESAWAL----TNI 147
Query: 596 PERLHKQTK*SMPVQYLYSF-SS*CQLMKNVCDQAVWALGNIIGDGPVLSRLL 751
+QTK + + +F S ++ +QAVWALGNI GDG V L+
Sbjct: 148 ASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLV 200
Score = 68.9 bits (161), Expect = 2e-11
Identities = 32/56 (57%), Positives = 38/56 (67%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTH 675
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL S H
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPH 175
Score = 38.3 bits (85), Expect = 0.030
Identities = 19/52 (36%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
ILP LV+ L D+P + +T WA++ + G + + VV G VP ++LL
Sbjct: 252 ILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLL 302
Score = 38.3 bits (85), Expect = 0.030
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
++P LV LS+AD Q E WA+TN S GT Q +VH G + + LL + K
Sbjct: 378 LVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
Score = 35.1 bits (77), Expect = 0.28
Identities = 20/52 (38%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
++P LV+ L ++ P + A+ NI +GT QT V+ AGA+ VF LL
Sbjct: 294 VVPQLVKLLGASELPIVT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLL 344
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +3
Query: 165 STDKMATDQAKNRMHVFKNAGKDVDEMRRRGMKSQSS*EKTKE 293
ST++ A A R+H FKN GKD EMRRR ++ K K+
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKK 43
>BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 81.0 bits (191), Expect = 4e-15
Identities = 67/173 (38%), Positives = 92/173 (53%), Gaps = 10/173 (5%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLATTD--LDELVMNAANAENPEA 427
V VELRK K+++ + KRRNV P ++ +E N T + +D++V N+ N E
Sbjct: 34 VNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIV-KGINSSNVEN 92
Query: 428 QLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFRGLT----IQRYSSRPLGL*QT*L 595
QL A Q RKLLS +K PPID +I AG P F +F G T IQ S+ L T +
Sbjct: 93 QLQATQAARKLLSREKQPPIDNIIRAGLIPK-FVSFLGRTDCSPIQFESAWAL----TNI 147
Query: 596 PERLHKQTK*SMPVQYLYSF-SS*CQLMKNVCDQAVWALGNIIGDGPVLSRLL 751
+QTK + + +F S ++ +QAVWALGNI GDG V L+
Sbjct: 148 ASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLV 200
Score = 68.5 bits (160), Expect = 2e-11
Identities = 32/56 (57%), Positives = 38/56 (67%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTH 675
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL S H
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPH 175
Score = 38.3 bits (85), Expect = 0.030
Identities = 19/52 (36%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
ILP LV+ L D+P + +T WA++ + G + + VV G VP ++LL
Sbjct: 252 ILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLL 302
Score = 38.3 bits (85), Expect = 0.030
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
++P LV LS+AD Q E WA+TN S GT Q +VH G + + LL + K
Sbjct: 378 LVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
Score = 35.1 bits (77), Expect = 0.28
Identities = 20/52 (38%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
++P LV+ L ++ P + A+ NI +GT QT V+ AGA+ VF LL
Sbjct: 294 VVPQLVKLLGASELPIVT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLL 344
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +3
Query: 165 STDKMATDQAKNRMHVFKNAGKDVDEMRRRGMKSQSS*EKTKE 293
ST++ A A R+H FKN GKD EMRRR ++ K K+
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKK 43
>AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2
protein.
Length = 529
Score = 81.0 bits (191), Expect = 4e-15
Identities = 67/173 (38%), Positives = 92/173 (53%), Gaps = 10/173 (5%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLATTD--LDELVMNAANAENPEA 427
V VELRK K+++ + KRRNV P ++ +E N T + +D++V N+ N E
Sbjct: 34 VNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIV-KGINSSNVEN 92
Query: 428 QLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFRGLT----IQRYSSRPLGL*QT*L 595
QL A Q RKLLS +K PPID +I AG P F +F G T IQ S+ L T +
Sbjct: 93 QLQATQAARKLLSREKQPPIDNIIRAGLIPK-FVSFLGRTDCSPIQFESAWAL----TNI 147
Query: 596 PERLHKQTK*SMPVQYLYSF-SS*CQLMKNVCDQAVWALGNIIGDGPVLSRLL 751
+QTK + + +F S ++ +QAVWALGNI GDG V L+
Sbjct: 148 ASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDLV 200
Score = 68.9 bits (161), Expect = 2e-11
Identities = 32/56 (57%), Positives = 38/56 (67%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTH 675
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL S H
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPH 175
Score = 38.3 bits (85), Expect = 0.030
Identities = 19/52 (36%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
ILP LV+ L D+P + +T WA++ + G + + VV G VP ++LL
Sbjct: 252 ILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLL 302
Score = 38.3 bits (85), Expect = 0.030
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
++P LV LS+AD Q E WA+TN S GT Q +VH G + + LL + K
Sbjct: 378 LVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
Score = 35.1 bits (77), Expect = 0.28
Identities = 20/52 (38%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
++P LV+ L ++ P + A+ NI +GT QT V+ AGA+ VF LL
Sbjct: 294 VVPQLVKLLGASELPIVT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLL 344
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +3
Query: 165 STDKMATDQAKNRMHVFKNAGKDVDEMRRRGMKSQSS*EKTKE 293
ST++ A A R+H FKN GKD EMRRR ++ K K+
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKK 43
>BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 79.0 bits (186), Expect = 2e-14
Identities = 66/173 (38%), Positives = 91/173 (52%), Gaps = 10/173 (5%)
Frame = +2
Query: 263 VTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLATTD--LDELVMNAANAENPEA 427
V VELRK K+++ + KRRNV P ++ +E N T + +D++V N+ N E
Sbjct: 34 VNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTVNWSVDDIV-KGINSSNVEN 92
Query: 428 QLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAFRGLT----IQRYSSRPLGL*QT*L 595
QL A Q RKLLS +K PPID +I AG P F +F G T IQ S+ L T +
Sbjct: 93 QLQATQAARKLLSREKQPPIDNIIRAGLIPK-FVSFLGRTDCSPIQFESAWAL----TNI 147
Query: 596 PERLHKQTK*SMPVQYLYSF-SS*CQLMKNVCDQAVWALGNIIGDGPVLSRLL 751
+QTK + + +F S ++ +Q VWALGNI GDG V L+
Sbjct: 148 ASGTSEQTKAVVDGGAIRAFISLLASPHAHISEQDVWALGNIAGDGSVFRDLV 200
Score = 65.3 bits (152), Expect = 2e-10
Identities = 31/56 (55%), Positives = 37/56 (66%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTH 675
++P V L R D +QFE+AWALTNIASGTS QT VV GA+ F+ LL S H
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIRAFISLLASPH 175
Score = 38.3 bits (85), Expect = 0.030
Identities = 19/52 (36%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
ILP LV+ L D+P + +T WA++ + G + + VV G VP ++LL
Sbjct: 252 ILPTLVRLLHH-DDPEVLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLL 302
Score = 38.3 bits (85), Expect = 0.030
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
++P LV LS+AD Q E WA+TN S GT Q +VH G + + LL + K
Sbjct: 378 LVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLLTAKDTK 435
Score = 35.1 bits (77), Expect = 0.28
Identities = 20/52 (38%), Positives = 30/52 (57%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
++P LV+ L ++ P + A+ NI +GT QT V+ AGA+ VF LL
Sbjct: 294 VVPQLVKLLGASELPIVT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLL 344
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/43 (44%), Positives = 25/43 (58%)
Frame = +3
Query: 165 STDKMATDQAKNRMHVFKNAGKDVDEMRRRGMKSQSS*EKTKE 293
ST++ A A R+H FKN GKD EMRRR ++ K K+
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKK 43
>BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 68.9 bits (161), Expect = 2e-11
Identities = 33/52 (63%), Positives = 39/52 (75%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E
Sbjct: 130 VEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFE 181
Score = 57.2 bits (132), Expect = 6e-08
Identities = 53/169 (31%), Positives = 84/169 (49%), Gaps = 13/169 (7%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPI----SYSTDEEEIDKNLATTDLDELV----MNAANAENPE 424
++LRK KRE+ L KRRNV + + D +D +++T + ++ + +++ +
Sbjct: 36 IQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESVITREMVEMLFSDDSD 95
Query: 425 AQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLGL*QT* 592
QLA Q+ RKLLS + +PPIDE+I F F T+Q ++ L T
Sbjct: 96 LQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQFEAAWAL----TN 151
Query: 593 LPERLHKQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGPV 736
+ +QTK + + F ++V +QAVWALGNI GD V
Sbjct: 152 IASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLL 663
I P+L++ L +A+ + E AWA+TN S GT Q +V G + LL
Sbjct: 379 IFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLL 430
Score = 30.7 bits (66), Expect = 6.0
Identities = 16/57 (28%), Positives = 30/57 (52%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
LP+L + L +D+ L + WAL+ ++ G + + V+ +G ++LLM K
Sbjct: 254 LPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYK 309
>BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 68.9 bits (161), Expect = 2e-11
Identities = 33/52 (63%), Positives = 39/52 (75%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E
Sbjct: 130 VEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFE 181
Score = 57.2 bits (132), Expect = 6e-08
Identities = 53/169 (31%), Positives = 84/169 (49%), Gaps = 13/169 (7%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPI----SYSTDEEEIDKNLATTDLDELV----MNAANAENPE 424
++LRK KRE+ L KRRNV + + D +D +++T + ++ + +++ +
Sbjct: 36 IQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESVITREMVEMLFSDDSD 95
Query: 425 AQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLGL*QT* 592
QLA Q+ RKLLS + +PPIDE+I F F T+Q ++ L T
Sbjct: 96 LQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQFEAAWAL----TN 151
Query: 593 LPERLHKQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGPV 736
+ +QTK + + F ++V +QAVWALGNI GD V
Sbjct: 152 IASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLL 663
I P+L++ L +A+ + E AWA+TN S GT Q +V G + LL
Sbjct: 379 IFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLL 430
Score = 30.7 bits (66), Expect = 6.0
Identities = 16/57 (28%), Positives = 30/57 (52%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
LP+L + L +D+ L + WAL+ ++ G + + V+ +G ++LLM K
Sbjct: 254 LPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYK 309
>AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 68.9 bits (161), Expect = 2e-11
Identities = 33/52 (63%), Positives = 39/52 (75%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E
Sbjct: 130 VEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFE 181
Score = 57.2 bits (132), Expect = 6e-08
Identities = 53/169 (31%), Positives = 84/169 (49%), Gaps = 13/169 (7%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPI----SYSTDEEEIDKNLATTDLDELV----MNAANAENPE 424
++LRK KRE+ L KRRNV + + D +D +++T + ++ + +++ +
Sbjct: 36 IQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESVITREMVEMLFSDDSD 95
Query: 425 AQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLGL*QT* 592
QLA Q+ RKLLS + +PPIDE+I F F T+Q ++ L T
Sbjct: 96 LQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQFEAAWAL----TN 151
Query: 593 LPERLHKQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGPV 736
+ +QTK + + F ++V +QAVWALGNI GD V
Sbjct: 152 IASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLL 663
I P+L++ L +A+ + E AWA+TN S GT Q +V G + LL
Sbjct: 379 IFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLL 430
Score = 30.7 bits (66), Expect = 6.0
Identities = 16/57 (28%), Positives = 30/57 (52%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
LP+L + L +D+ L + WAL+ ++ G + + V+ +G ++LLM K
Sbjct: 254 LPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYK 309
>AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 68.9 bits (161), Expect = 2e-11
Identities = 33/52 (63%), Positives = 39/52 (75%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E
Sbjct: 130 VEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFE 181
Score = 57.2 bits (132), Expect = 6e-08
Identities = 53/169 (31%), Positives = 84/169 (49%), Gaps = 13/169 (7%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPI----SYSTDEEEIDKNLATTDLDELV----MNAANAENPE 424
++LRK KRE+ L KRRNV + + D +D +++T + ++ + +++ +
Sbjct: 36 IQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESVITREMVEMLFSDDSD 95
Query: 425 AQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLGL*QT* 592
QLA Q+ RKLLS + +PPIDE+I F F T+Q ++ L T
Sbjct: 96 LQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQFEAAWAL----TN 151
Query: 593 LPERLHKQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGPV 736
+ +QTK + + F ++V +QAVWALGNI GD V
Sbjct: 152 IASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLL 663
I P+L++ L +A+ + E AWA+TN S GT Q +V G + LL
Sbjct: 379 IFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLL 430
Score = 30.7 bits (66), Expect = 6.0
Identities = 16/57 (28%), Positives = 30/57 (52%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
LP+L + L +D+ L + WAL+ ++ G + + V+ +G ++LLM K
Sbjct: 254 LPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYK 309
>AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subunit
protein.
Length = 536
Score = 68.9 bits (161), Expect = 2e-11
Identities = 33/52 (63%), Positives = 39/52 (75%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E
Sbjct: 130 VEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFE 181
Score = 57.2 bits (132), Expect = 6e-08
Identities = 53/169 (31%), Positives = 84/169 (49%), Gaps = 13/169 (7%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPI----SYSTDEEEIDKNLATTDLDELV----MNAANAENPE 424
++LRK KRE+ L KRRNV + + D +D +++T + ++ + +++ +
Sbjct: 36 IQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESVITREMVEMLFSDDSD 95
Query: 425 AQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLGL*QT* 592
QLA Q+ RKLLS + +PPIDE+I F F T+Q ++ L T
Sbjct: 96 LQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQFEAAWAL----TN 151
Query: 593 LPERLHKQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGDGPV 736
+ +QTK + + F ++V +QAVWALGNI GD V
Sbjct: 152 IASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSV 200
Score = 33.5 bits (73), Expect = 0.85
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLL 663
I P+L++ L +A+ + E AWA+TN S GT Q +V G + LL
Sbjct: 379 IFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLL 430
Score = 30.7 bits (66), Expect = 6.0
Identities = 16/57 (28%), Positives = 30/57 (52%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
LP+L + L +D+ L + WAL+ ++ G + + V+ +G ++LLM K
Sbjct: 254 LPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYK 309
>CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein.
Length = 538
Score = 66.5 bits (155), Expect = 1e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E
Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFE 183
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/172 (34%), Positives = 87/172 (50%), Gaps = 19/172 (11%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPISYSTDEEEI--DKNLATTDLDELVMNAAN----------- 409
++LRK KREE L KRRNV + EEE+ D ++ + M
Sbjct: 33 LQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMIEMIF 92
Query: 410 AENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLG 577
+++PE QL+A Q+ RKLLS + NPPIDE+I+ + F F T+Q S+ L
Sbjct: 93 SKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLT 152
Query: 578 --L*QT*LPERLHKQTK*SMPVQYLYSFSS*CQLMKNVCDQAVWALGNIIGD 727
L R+ Q ++P+ ++ SS ++V +QAVWALGNI GD
Sbjct: 153 NIASGNSLQTRIVIQAG-AVPI-FIELLSS---EFEDVQEQAVWALGNIAGD 199
Score = 31.9 bits (69), Expect = 2.6
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQLL 663
I P L+ L A+ + E AWA+TN SG SA+ K +V G + LL
Sbjct: 381 IFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
>BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 66.5 bits (155), Expect = 1e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E
Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFE 183
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/172 (34%), Positives = 87/172 (50%), Gaps = 19/172 (11%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPISYSTDEEEI--DKNLATTDLDELVMNAAN----------- 409
++LRK KREE L KRRNV + EEE+ D ++ + M
Sbjct: 33 LQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMIEMIF 92
Query: 410 AENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLG 577
+++PE QL+A Q+ RKLLS + NPPIDE+I+ + F F T+Q S+ L
Sbjct: 93 SKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLT 152
Query: 578 --L*QT*LPERLHKQTK*SMPVQYLYSFSS*CQLMKNVCDQAVWALGNIIGD 727
L R+ Q ++P+ ++ SS ++V +QAVWALGNI GD
Sbjct: 153 NIASGNSLQTRIVIQAG-AVPI-FIELLSS---EFEDVQEQAVWALGNIAGD 199
Score = 31.9 bits (69), Expect = 2.6
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQLL 663
I P L+ L A+ + E AWA+TN SG SA+ K +V G + LL
Sbjct: 381 IFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
>BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 66.5 bits (155), Expect = 1e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E
Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFE 183
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/172 (34%), Positives = 87/172 (50%), Gaps = 19/172 (11%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPISYSTDEEEI--DKNLATTDLDELVMNAAN----------- 409
++LRK KREE L KRRNV + EEE+ D ++ + M
Sbjct: 33 LQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMIEMIF 92
Query: 410 AENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLG 577
+++PE QL+A Q+ RKLLS + NPPIDE+I+ + F F T+Q S+ L
Sbjct: 93 SKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLT 152
Query: 578 --L*QT*LPERLHKQTK*SMPVQYLYSFSS*CQLMKNVCDQAVWALGNIIGD 727
L R+ Q ++P+ ++ SS ++V +QAVWALGNI GD
Sbjct: 153 NIASGNSLQTRIVIQAG-AVPI-FIELLSS---EFEDVQEQAVWALGNIAGD 199
Score = 31.9 bits (69), Expect = 2.6
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQLL 663
I P L+ L A+ + E AWA+TN SG SA+ K +V G + LL
Sbjct: 381 IFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 30.7 bits (66), Expect = 6.0
Identities = 17/59 (28%), Positives = 30/59 (50%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHEKRM 687
+PI ++ LS ++ +Q + WAL NIA ++ + V+ +P LQL + M
Sbjct: 171 VPIFIELLS-SEFEDVQEQAVWALGNIAGDSTMYRDYVLDCNILPPLLQLFSKQNRLTM 228
>BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 66.5 bits (155), Expect = 1e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E
Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFE 183
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/172 (34%), Positives = 87/172 (50%), Gaps = 19/172 (11%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPISYSTDEEEI--DKNLATTDLDELVMNAAN----------- 409
++LRK KREE L KRRNV + EEE+ D ++ + M
Sbjct: 33 LQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMIEMIF 92
Query: 410 AENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLG 577
+++PE QL+A Q+ RKLLS + NPPIDE+I+ + F F T+Q S+ L
Sbjct: 93 SKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLT 152
Query: 578 --L*QT*LPERLHKQTK*SMPVQYLYSFSS*CQLMKNVCDQAVWALGNIIGD 727
L R+ Q ++P+ ++ SS ++V +QAVWALGNI GD
Sbjct: 153 NIASGNSLQTRIVIQAG-AVPI-FIELLSS---EFEDVQEQAVWALGNIAGD 199
Score = 31.9 bits (69), Expect = 2.6
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQLL 663
I P L+ L A+ + E AWA+TN SG SA+ K +V G + LL
Sbjct: 381 IFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
>BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 66.5 bits (155), Expect = 1e-10
Identities = 31/52 (59%), Positives = 38/52 (73%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E
Sbjct: 132 VEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFE 183
Score = 62.5 bits (145), Expect = 2e-09
Identities = 60/172 (34%), Positives = 87/172 (50%), Gaps = 19/172 (11%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPISYSTDEEEI--DKNLATTDLDELVMNAAN----------- 409
++LRK KREE L KRRNV + EEE+ D ++ + M
Sbjct: 33 LQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQINNMEMAPGGVITSDMIEMIF 92
Query: 410 AENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLG 577
+++PE QL+A Q+ RKLLS + NPPIDE+I+ + F F T+Q S+ L
Sbjct: 93 SKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLT 152
Query: 578 --L*QT*LPERLHKQTK*SMPVQYLYSFSS*CQLMKNVCDQAVWALGNIIGD 727
L R+ Q ++P+ ++ SS ++V +QAVWALGNI GD
Sbjct: 153 NIASGNSLQTRIVIQAG-AVPI-FIELLSS---EFEDVQEQAVWALGNIAGD 199
Score = 31.9 bits (69), Expect = 2.6
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQLL 663
I P L+ L A+ + E AWA+TN SG SA+ K +V G + LL
Sbjct: 381 IFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
>BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 66.1 bits (154), Expect = 1e-10
Identities = 31/52 (59%), Positives = 37/52 (71%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL S HE
Sbjct: 133 VKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHE 184
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/170 (31%), Positives = 77/170 (45%), Gaps = 17/170 (10%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLDELV------------MNAANA 412
++LRK KREE L KRRNV + DE ++ + D+ V + +
Sbjct: 36 IQLRKQKREEQLFKRRNVYLP-RNDESMLESPIQDPDISSTVPIPEEEVVTTDMVQMIFS 94
Query: 413 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLGL 580
N + QL A Q+ RKLLS + NPPID++I F F T+Q ++ L
Sbjct: 95 NNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWAL-- 152
Query: 581 *QT*LPERLHKQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGD 727
T + TK + + F ++V +QAVWALGNI GD
Sbjct: 153 --TNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGD 200
Score = 33.1 bits (72), Expect = 1.1
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLL 663
I P+L++ L +A+ + E AWA+TN S GT Q +V G + LL
Sbjct: 382 IFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVALGCIKPLCDLL 433
>AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 66.1 bits (154), Expect = 1e-10
Identities = 31/52 (59%), Positives = 37/52 (71%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL S HE
Sbjct: 133 VKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHE 184
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/170 (31%), Positives = 77/170 (45%), Gaps = 17/170 (10%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLDELV------------MNAANA 412
++LRK KREE L KRRNV + DE ++ + D+ V + +
Sbjct: 36 IQLRKQKREEQLFKRRNVYLP-RNDESMLESPIQDPDISSTVPIPEEEVVTTDMVQMIFS 94
Query: 413 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLGL 580
N + QL A Q+ RKLLS + NPPID++I F F T+Q ++ L
Sbjct: 95 NNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWAL-- 152
Query: 581 *QT*LPERLHKQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGD 727
T + TK + + F ++V +QAVWALGNI GD
Sbjct: 153 --TNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGD 200
Score = 33.1 bits (72), Expect = 1.1
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLL 663
I P+L++ L +A+ + E AWA+TN S GT Q +V G + LL
Sbjct: 382 IFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVALGCIKPLCDLL 433
>AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein.
Length = 536
Score = 66.1 bits (154), Expect = 1e-10
Identities = 31/52 (59%), Positives = 37/52 (71%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL S HE
Sbjct: 130 VKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHE 181
Score = 54.4 bits (125), Expect = 4e-07
Identities = 54/170 (31%), Positives = 79/170 (46%), Gaps = 17/170 (10%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLDELV------------MNAANA 412
++LRK KREE L KRRNV + + DE ++ + +D+ V + +
Sbjct: 33 IQLRKQKREEQLFKRRNVYLPRN-DESMLESPIQDSDISSTVPIPEEGVVTTDMVQMIFS 91
Query: 413 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLGL 580
N + QL A Q+ RKLLS + NPPID++I F F T+Q ++ L
Sbjct: 92 NNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQFEAAWAL-- 149
Query: 581 *QT*LPERLHKQTK*SMPVQYLYSFSS*CQL-MKNVCDQAVWALGNIIGD 727
T + TK + + F ++V +QAVWALGNI GD
Sbjct: 150 --TNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGD 197
Score = 33.1 bits (72), Expect = 1.1
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQLL 663
I P+L++ L +A+ + E AWA+TN S GT Q +V G + LL
Sbjct: 379 IFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVALGCIKPLCDLL 430
>S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor 1
protein.
Length = 538
Score = 63.7 bits (148), Expect = 7e-10
Identities = 30/52 (57%), Positives = 38/52 (73%)
Frame = +1
Query: 523 VQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHE 678
V+ L R +N +LQFE+AW LTNIASG S QT V+ A AVP+F++LL S E
Sbjct: 132 VEFLKRKENCSLQFESAWVLTNIASGNSLQTRIVIQARAVPIFIELLSSEFE 183
Score = 62.1 bits (144), Expect = 2e-09
Identities = 59/172 (34%), Positives = 87/172 (50%), Gaps = 19/172 (11%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPISYSTDEEEI--DKNLATTDLDELVMNAAN----------- 409
++LRK KREE L KRRNV + EEE+ D + + M
Sbjct: 33 LQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQISNMEMAPGGVITSDMIEMIF 92
Query: 410 AENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGYSPS*FSAF----RGLTIQRYSSRPLG 577
+++PE QL+A Q+ RKLLS + NPPIDE+I+ + F F ++Q S+ L
Sbjct: 93 SKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCSLQFESAWVLT 152
Query: 578 --L*QT*LPERLHKQTK*SMPVQYLYSFSS*CQLMKNVCDQAVWALGNIIGD 727
L R+ Q + ++P+ ++ SS ++V +QAVWALGNI GD
Sbjct: 153 NIASGNSLQTRIVIQAR-AVPI-FIELLSS---EFEDVQEQAVWALGNIAGD 199
Score = 31.9 bits (69), Expect = 2.6
Identities = 20/53 (37%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Frame = +1
Query: 508 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQLL 663
I P L+ L A+ + E AWA+TN SG SA+ K +V G + LL
Sbjct: 381 IFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
>AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 142
Score = 50.4 bits (115), Expect = 7e-06
Identities = 33/89 (37%), Positives = 47/89 (52%), Gaps = 12/89 (13%)
Frame = +2
Query: 269 VELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLDELV------------MNAANA 412
++LRK KREE L KRRNV + DE ++ + D+ V + +
Sbjct: 33 IQLRKQKREEQLFKRRNVYLP-RNDESMLESPIQDPDISSTVPIPEEEVVTTDMVQMIFS 91
Query: 413 ENPEAQLAAVQQCRKLLSCDKNPPIDELI 499
N + QL A Q+ RKLLS + NPPID++I
Sbjct: 92 NNADQQLTATQKFRKLLSKEPNPPIDQVI 120
>CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein.
Length = 509
Score = 35.9 bits (79), Expect = 0.16
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +1
Query: 502 CWILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 654
C L LV CL D P ++ AWAL IA + + VV AGAVP+ +
Sbjct: 124 CGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSRAVVDAGAVPLLV 173
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMST 672
+P L CLS ++ AWAL I T V +PV L L MST
Sbjct: 337 VPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMST 390
>BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 35.9 bits (79), Expect = 0.16
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +1
Query: 502 CWILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 654
C L LV CL D P ++ AWAL IA + + VV AGAVP+ +
Sbjct: 124 CGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMST 672
+P L CLS ++ AWAL I T V +PV L L MST
Sbjct: 337 VPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMST 390
>AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antigen 6
protein.
Length = 509
Score = 35.9 bits (79), Expect = 0.16
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +1
Query: 502 CWILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 654
C L LV CL D P ++ AWAL IA + + VV AGAVP+ +
Sbjct: 124 CGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMST 672
+P L CLS ++ AWAL I T V +PV L L MST
Sbjct: 337 VPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMST 390
>AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 35.9 bits (79), Expect = 0.16
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +1
Query: 502 CWILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 654
C L LV CL D P ++ AWAL IA + + VV AGAVP+ +
Sbjct: 124 CGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMST 672
+P L CLS ++ AWAL I T V +PV L L MST
Sbjct: 337 VPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMST 390
>AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antigen
6 protein.
Length = 509
Score = 35.9 bits (79), Expect = 0.16
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +1
Query: 502 CWILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 654
C L LV CL D P ++ AWAL IA + + VV AGAVP+ +
Sbjct: 124 CGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMST 672
+P L CLS ++ AWAL I T V +PV L L MST
Sbjct: 337 VPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMST 390
>AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antigen
6 protein.
Length = 458
Score = 35.9 bits (79), Expect = 0.16
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +1
Query: 502 CWILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 654
C L LV CL D P ++ AWAL IA + + VV AGAVP+ +
Sbjct: 124 CGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMST 672
+P L CLS ++ AWAL I T V +PV L L MST
Sbjct: 337 VPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMST 390
>AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein
Repro-SA-1 protein.
Length = 509
Score = 35.9 bits (79), Expect = 0.16
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +1
Query: 502 CWILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 654
C L LV CL D P ++ AWAL IA + + VV AGAVP+ +
Sbjct: 124 CGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMST 672
+P L CLS ++ AWAL I T V +PV L L MST
Sbjct: 337 VPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMST 390
>AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antigen 6
protein.
Length = 246
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/48 (43%), Positives = 25/48 (52%)
Frame = +1
Query: 502 CWILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVP 645
C L LV CL D P ++ AWAL IA + + VV AGAVP
Sbjct: 200 CGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVP 246
>AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antigen
6 protein.
Length = 246
Score = 35.1 bits (77), Expect = 0.28
Identities = 21/48 (43%), Positives = 25/48 (52%)
Frame = +1
Query: 502 CWILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVP 645
C L LV CL D P ++ AWAL IA + + VV AGAVP
Sbjct: 200 CGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVP 246
>AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 321
Score = 34.7 bits (76), Expect = 0.37
Identities = 15/30 (50%), Positives = 23/30 (76%)
Frame = +2
Query: 410 AENPEAQLAAVQQCRKLLSCDKNPPIDELI 499
+++ + QLA Q+ RKLLS + +PPIDE+I
Sbjct: 42 SDDSDLQLATTQKFRKLLSKEPSPPIDEVI 71
Score = 30.7 bits (66), Expect = 6.0
Identities = 16/57 (28%), Positives = 30/57 (52%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSTHEK 681
LP+L + L +D+ L + WAL+ ++ G + + V+ +G ++LLM K
Sbjct: 161 LPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYK 216
>AL513128-2|CAH72208.1| 191|Homo sapiens sperm associated antigen 6
protein.
Length = 191
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMST 672
+P L CLS ++ AWAL I T V +PV L L MST
Sbjct: 98 VPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMST 151
>AL158211-13|CAI15961.1| 191|Homo sapiens sperm associated antigen
6 protein.
Length = 191
Score = 34.3 bits (75), Expect = 0.48
Identities = 19/54 (35%), Positives = 23/54 (42%)
Frame = +1
Query: 511 LPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMST 672
+P L CLS ++ AWAL I T V +PV L L MST
Sbjct: 98 VPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYMST 151
>Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein.
Length = 281
Score = 32.3 bits (70), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +1
Query: 565 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 663
E W L+NI +G Q V+ A VP+ + LL
Sbjct: 105 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLL 137
>M82962-1|AAA21338.1| 746|Homo sapiens
N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase alpha
subunit protein.
Length = 746
Score = 31.1 bits (67), Expect = 4.5
Identities = 12/40 (30%), Positives = 21/40 (52%)
Frame = -1
Query: 580 KPKRSRTVTLDCQPSKGTELGWGVSSSYELINRRVFITRE 461
+P R T DC + +LGW S++++ RR F+ +
Sbjct: 546 RPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKND 585
>BC131714-1|AAI31715.1| 746|Homo sapiens meprin A, alpha (PABA
peptide hydrolase) protein.
Length = 746
Score = 31.1 bits (67), Expect = 4.5
Identities = 12/40 (30%), Positives = 21/40 (52%)
Frame = -1
Query: 580 KPKRSRTVTLDCQPSKGTELGWGVSSSYELINRRVFITRE 461
+P R T DC + +LGW S++++ RR F+ +
Sbjct: 546 RPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKND 585
>AL161618-1|CAC21508.1| 746|Homo sapiens meprin A, alpha (PABA
peptide hydrolase) protein.
Length = 746
Score = 31.1 bits (67), Expect = 4.5
Identities = 12/40 (30%), Positives = 21/40 (52%)
Frame = -1
Query: 580 KPKRSRTVTLDCQPSKGTELGWGVSSSYELINRRVFITRE 461
+P R T DC + +LGW S++++ RR F+ +
Sbjct: 546 RPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKND 585
>AF478685-1|AAL85339.1| 746|Homo sapiens
N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase alpha
subunit protein.
Length = 746
Score = 31.1 bits (67), Expect = 4.5
Identities = 12/40 (30%), Positives = 21/40 (52%)
Frame = -1
Query: 580 KPKRSRTVTLDCQPSKGTELGWGVSSSYELINRRVFITRE 461
+P R T DC + +LGW S++++ RR F+ +
Sbjct: 546 RPSRVGTYHTDCNCFRSIDLGWSGFISHQMLKRRSFLKND 585
>BC111961-1|AAI11962.1| 387|Homo sapiens hypothetical protein
LOC205860 protein.
Length = 387
Score = 30.3 bits (65), Expect = 7.9
Identities = 10/28 (35%), Positives = 17/28 (60%)
Frame = -3
Query: 260 HSSPAHFIDIFACILEHMHAVFRLISRH 177
H PAH D+ C + + ++FR++ RH
Sbjct: 173 HLEPAHITDLSLCHIRGLSSMFRVLQRH 200
>BC111959-1|AAI11960.1| 387|Homo sapiens hypothetical protein
FLJ25801 protein.
Length = 387
Score = 30.3 bits (65), Expect = 7.9
Identities = 10/28 (35%), Positives = 17/28 (60%)
Frame = -3
Query: 260 HSSPAHFIDIFACILEHMHAVFRLISRH 177
H PAH D+ C + + ++FR++ RH
Sbjct: 173 HLEPAHITDLSLCHIRGLSSMFRVLQRH 200
>AK098667-1|BAC05372.1| 387|Homo sapiens protein ( Homo sapiens
cDNA FLJ25801 fis, clone TST07120. ).
Length = 387
Score = 30.3 bits (65), Expect = 7.9
Identities = 10/28 (35%), Positives = 17/28 (60%)
Frame = -3
Query: 260 HSSPAHFIDIFACILEHMHAVFRLISRH 177
H PAH D+ C + + ++FR++ RH
Sbjct: 173 HLEPAHITDLSLCHIRGLSSMFRVLQRH 200
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,978,814
Number of Sequences: 237096
Number of extensions: 2451885
Number of successful extensions: 5635
Number of sequences better than 10.0: 56
Number of HSP's better than 10.0 without gapping: 5061
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5601
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9183116696
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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