BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= pg--0353.Seq (758 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q17KL4 Cluster: Inward rectifier potassium channel, put... 76 8e-13 UniRef50_Q9VCL9 Cluster: CG4370-PA, isoform A; n=14; Endopterygo... 71 3e-11 UniRef50_Q16XB9 Cluster: Inwardly rectifying k+ channel, putativ... 70 7e-11 UniRef50_A2RVC9 Cluster: IP03029p; n=5; Sophophora|Rep: IP03029p... 67 4e-10 UniRef50_UPI0000D56E2D Cluster: PREDICTED: similar to CG4370-PA,... 67 5e-10 UniRef50_Q21458 Cluster: Inward rectifying k (Potassium) channel... 67 5e-10 UniRef50_UPI0000D56E2C Cluster: PREDICTED: similar to CG4370-PA,... 66 7e-10 UniRef50_Q16XB5 Cluster: Inwardly rectifying k+ channel, putativ... 65 2e-09 UniRef50_P48048 Cluster: ATP-sensitive inward rectifier potassiu... 60 8e-08 UniRef50_Q9VJ56 Cluster: CG10369-PA; n=2; Sophophora|Rep: CG1036... 57 4e-07 UniRef50_Q8WST7 Cluster: Inwardly rectifying potassium channel; ... 57 4e-07 UniRef50_P52192 Cluster: Inward rectifier potassium channel irk-... 57 4e-07 UniRef50_UPI0000E81615 Cluster: PREDICTED: similar to potassium ... 56 9e-07 UniRef50_A7SE20 Cluster: Predicted protein; n=1; Nematostella ve... 55 2e-06 UniRef50_UPI0000D57724 Cluster: PREDICTED: similar to CG4370-PA,... 52 1e-05 UniRef50_UPI0000ECB8AB Cluster: ATP-sensitive inward rectifier p... 52 1e-05 UniRef50_Q15842 Cluster: ATP-sensitive inward rectifier potassiu... 52 1e-05 UniRef50_A7RUM3 Cluster: Predicted protein; n=2; Nematostella ve... 52 2e-05 UniRef50_Q4SEH7 Cluster: Chromosome undetermined SCAF14620, whol... 50 6e-05 UniRef50_P48050 Cluster: Inward rectifier potassium channel 4 (P... 50 6e-05 UniRef50_Q969A5 Cluster: G-protein coupled inwardly rectifying p... 48 3e-04 UniRef50_UPI00005873FD Cluster: PREDICTED: hypothetical protein;... 48 3e-04 UniRef50_Q9NPI9 Cluster: Inward rectifier potassium channel 16 (... 47 6e-04 UniRef50_P48051 Cluster: G protein-activated inward rectifier po... 46 0.001 UniRef50_UPI0000F1FEA6 Cluster: PREDICTED: similar to G protein-... 45 0.002 UniRef50_Q1IM86 Cluster: K+ channel, inward rectifier; n=1; Acid... 44 0.004 UniRef50_P78508 Cluster: ATP-sensitive inward rectifier potassiu... 44 0.004 UniRef50_UPI000058708F Cluster: PREDICTED: similar to Inward rec... 44 0.005 UniRef50_Q8R1Z6 Cluster: Kcnj14 protein; n=4; Eutheria|Rep: Kcnj... 44 0.005 UniRef50_A7S217 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.005 UniRef50_A7SH65 Cluster: Predicted protein; n=1; Nematostella ve... 43 0.007 UniRef50_O08871 Cluster: G-protein coupled inward rectifier pota... 42 0.022 UniRef50_Q969A6 Cluster: G-protein coupled inwardly rectifying p... 42 0.022 UniRef50_UPI00005A5397 Cluster: PREDICTED: similar to potassium ... 41 0.029 UniRef50_Q93849 Cluster: Putative uncharacterized protein irk-3;... 41 0.029 UniRef50_UPI000155C4DF Cluster: PREDICTED: similar to inwardly r... 40 0.050 UniRef50_Q4RG50 Cluster: Chromosome 2 SCAF15106, whole genome sh... 40 0.050 UniRef50_P48549 Cluster: G protein-activated inward rectifier po... 40 0.067 UniRef50_UPI0000EB0168 Cluster: G protein-activated inward recti... 38 0.20 UniRef50_Q4SN97 Cluster: Chromosome 8 SCAF14543, whole genome sh... 38 0.20 UniRef50_UPI0000586212 Cluster: PREDICTED: similar to BIK; Kir2.... 37 0.47 UniRef50_A6H129 Cluster: Inward rectifier potassium channel Irk;... 37 0.62 UniRef50_Q2JL46 Cluster: Putative uncharacterized protein; n=1; ... 36 0.82 UniRef50_A6RBQ6 Cluster: Predicted protein; n=1; Ajellomyces cap... 36 1.4 UniRef50_A7HIG5 Cluster: K channel inward rectifier conserved re... 34 3.3 UniRef50_Q23K61 Cluster: HECT domain and RCC1-like domain-contai... 34 4.4 UniRef50_UPI0000D57723 Cluster: PREDICTED: similar to Inward rec... 33 5.8 >UniRef50_Q17KL4 Cluster: Inward rectifier potassium channel, putative; n=3; Culicidae|Rep: Inward rectifier potassium channel, putative - Aedes aegypti (Yellowfever mosquito) Length = 419 Score = 76.2 bits (179), Expect = 8e-13 Identities = 33/73 (45%), Positives = 49/73 (67%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 LTG + G VT++RTSY+ EI WG+RF+N++ Y + E Y E++D +E V+TPLC Sbjct: 281 LTGGTMTTGQVTEARTSYVPGEIYWGHRFQNIIMYDRAHEHYVAHNEHMDVLEPVDTPLC 340 Query: 183 SACRLKDFEDNMK 221 SA RL++ +K Sbjct: 341 SARRLEEVLKEVK 353 >UniRef50_Q9VCL9 Cluster: CG4370-PA, isoform A; n=14; Endopterygota|Rep: CG4370-PA, isoform A - Drosophila melanogaster (Fruit fly) Length = 453 Score = 70.9 bits (166), Expect = 3e-11 Identities = 32/78 (41%), Positives = 49/78 (62%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G+ ++ G TQ+R+SY++ EI+WG+RF V+ Y+K+ +AY ID + QV+TPLC Sbjct: 358 LEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVDTPLC 417 Query: 183 SACRLKDFEDNMKDSNTP 236 SA L + + TP Sbjct: 418 SARELNEIYKIQEGFRTP 435 >UniRef50_Q16XB9 Cluster: Inwardly rectifying k+ channel, putative; n=2; Aedes aegypti|Rep: Inwardly rectifying k+ channel, putative - Aedes aegypti (Yellowfever mosquito) Length = 489 Score = 69.7 bits (163), Expect = 7e-11 Identities = 34/81 (41%), Positives = 53/81 (65%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G+ ++ G TQ+R+SYL+ EI+WG RF+ VL +SKEK++Y I+ + E VETP C Sbjct: 345 LEGTIESTGQSTQARSSYLNTEILWGRRFEPVLCFSKEKQSYVINFSMFNDTEPVETPNC 404 Query: 183 SACRLKDFEDNMKDSNTPTVL 245 SA K+F + + ++ +L Sbjct: 405 SA---KEFAEGLNYNSNENLL 422 >UniRef50_A2RVC9 Cluster: IP03029p; n=5; Sophophora|Rep: IP03029p - Drosophila melanogaster (Fruit fly) Length = 535 Score = 67.3 bits (157), Expect = 4e-10 Identities = 33/91 (36%), Positives = 50/91 (54%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G ++ G TQ+R+SYL E++WG+RF NV+ + KE Y +D + V+TPLC Sbjct: 290 LEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFNNTYDVDTPLC 349 Query: 183 SACRLKDFEDNMKDSNTPTVLTQQCPFRQQT 275 SA +L D +K + + PF +T Sbjct: 350 SAKQL----DELKSEYSKSAKCVNAPFADRT 376 >UniRef50_UPI0000D56E2D Cluster: PREDICTED: similar to CG4370-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG4370-PA, isoform A - Tribolium castaneum Length = 391 Score = 66.9 bits (156), Expect = 5e-10 Identities = 27/73 (36%), Positives = 47/73 (64%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G++++ G +TQ+++SYL +EIIWG +F+++L ++ ++ + D D V V TPLC Sbjct: 282 LEGTTQSTGQMTQAKSSYLPREIIWGKKFQSLLNFNYDRREFEADFSKFDQVLAVSTPLC 341 Query: 183 SACRLKDFEDNMK 221 SA + D+ K Sbjct: 342 SAAYIDDYNQMQK 354 >UniRef50_Q21458 Cluster: Inward rectifying k (Potassium) channel family protein 2; n=2; Caenorhabditis|Rep: Inward rectifying k (Potassium) channel family protein 2 - Caenorhabditis elegans Length = 514 Score = 66.9 bits (156), Expect = 5e-10 Identities = 29/66 (43%), Positives = 41/66 (62%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G +++G+ TQ+RTSYL EI+WG+RF+ ++ Y KE Y ID V V TP C Sbjct: 336 LEGVVESVGSTTQARTSYLPSEILWGHRFEKLVHYKKENGQYNIDFGKFHNVYSVNTPTC 395 Query: 183 SACRLK 200 SA ++ Sbjct: 396 SAAEIE 401 >UniRef50_UPI0000D56E2C Cluster: PREDICTED: similar to CG4370-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG4370-PA, isoform A - Tribolium castaneum Length = 427 Score = 66.5 bits (155), Expect = 7e-10 Identities = 26/68 (38%), Positives = 43/68 (63%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L + ++ G Q+RTSY+ EI+WG+RF+ V+ Y+K+++ Y ++ D V+TPLC Sbjct: 303 LEATVESTGQSIQARTSYVGSEILWGHRFEPVVSYNKDRQGYEVNYSKFDNTYPVDTPLC 362 Query: 183 SACRLKDF 206 S L +F Sbjct: 363 SGAELAEF 370 >UniRef50_Q16XB5 Cluster: Inwardly rectifying k+ channel, putative; n=7; Endopterygota|Rep: Inwardly rectifying k+ channel, putative - Aedes aegypti (Yellowfever mosquito) Length = 449 Score = 64.9 bits (151), Expect = 2e-09 Identities = 26/72 (36%), Positives = 46/72 (63%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G ++ G TQ+R+SYL E++WG+RF++V+ + +E Y +D + +V+TPLC Sbjct: 276 LEGVVESTGMTTQARSSYLPSEVLWGHRFESVVSFKRETGEYEVDYTMFNNTYEVDTPLC 335 Query: 183 SACRLKDFEDNM 218 SA +L ++ + Sbjct: 336 SARQLHQVKEEL 347 >UniRef50_P48048 Cluster: ATP-sensitive inward rectifier potassium channel 1; n=48; Euteleostomi|Rep: ATP-sensitive inward rectifier potassium channel 1 - Homo sapiens (Human) Length = 391 Score = 59.7 bits (138), Expect = 8e-08 Identities = 29/75 (38%), Positives = 43/75 (57%), Gaps = 2/75 (2%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G+ ++ A Q RTSY+ +E++WGYRF ++ +KE + Y +D N +VETP C Sbjct: 297 LDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK-YRVDFHNFSKTVEVETPHC 355 Query: 183 SAC--RLKDFEDNMK 221 + C KD MK Sbjct: 356 AMCLYNEKDVRARMK 370 >UniRef50_Q9VJ56 Cluster: CG10369-PA; n=2; Sophophora|Rep: CG10369-PA - Drosophila melanogaster (Fruit fly) Length = 442 Score = 57.2 bits (132), Expect = 4e-07 Identities = 22/59 (37%), Positives = 36/59 (61%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPL 179 + G+S +T+++TSYL +EI WG RF N++ Y + E Y +D EN + V+ P+ Sbjct: 370 IVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMPM 428 >UniRef50_Q8WST7 Cluster: Inwardly rectifying potassium channel; n=1; Halocynthia roretzi|Rep: Inwardly rectifying potassium channel - Halocynthia roretzi (Sea squirt) Length = 745 Score = 57.2 bits (132), Expect = 4e-07 Identities = 28/71 (39%), Positives = 43/71 (60%), Gaps = 1/71 (1%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLD-TVEQVETPL 179 L G + G TQ+R SY+ EI+WG+RF+NV+ +S+ Y +D D + E ETP Sbjct: 402 LEGMVEATGMTTQARASYVPDEIMWGHRFENVITFSRTSR-YNVDFRKFDRSYEVPETPK 460 Query: 180 CSACRLKDFED 212 CS+ L+D ++ Sbjct: 461 CSSKYLQDMQN 471 >UniRef50_P52192 Cluster: Inward rectifier potassium channel irk-1; n=2; Caenorhabditis|Rep: Inward rectifier potassium channel irk-1 - Caenorhabditis elegans Length = 505 Score = 57.2 bits (132), Expect = 4e-07 Identities = 24/74 (32%), Positives = 40/74 (54%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G ++ G Q++TSYL E++WG+RF+ ++ Y + +Y ID + + V TP Sbjct: 330 LEGIVESTGMTAQAKTSYLPSEVLWGHRFRKLVTYQRSNGSYQIDYDLFHSTYPVRTPAM 389 Query: 183 SACRLKDFEDNMKD 224 S + N+KD Sbjct: 390 SPAEFYSSKPNLKD 403 >UniRef50_UPI0000E81615 Cluster: PREDICTED: similar to potassium inwardly-rectifying channel J5; n=3; Tetrapoda|Rep: PREDICTED: similar to potassium inwardly-rectifying channel J5 - Gallus gallus Length = 557 Score = 56.0 bits (129), Expect = 9e-07 Identities = 30/87 (34%), Positives = 48/87 (55%), Gaps = 1/87 (1%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G + G Q+RTSY EI+WGYRF+ + S EK A+ +D + +V+TP Sbjct: 468 LEGIVEATGMTCQARTSYTEDEILWGYRFEPCM--SLEKGAFRVDYSRFELTFEVQTPAV 525 Query: 183 SACRLKDF-EDNMKDSNTPTVLTQQCP 260 SA +++ E +D +TP++ + P Sbjct: 526 SAREMQEMAELERRDRSTPSLCWELLP 552 >UniRef50_A7SE20 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 317 Score = 55.2 bits (127), Expect = 2e-06 Identities = 25/63 (39%), Positives = 40/63 (63%), Gaps = 1/63 (1%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEA-YAIDIENLDTVEQVETPL 179 L G+ + G +TQ++TSY+ +EI+WGY FKN L ++ K + ++ + D V V+TP Sbjct: 255 LEGTVEATGMLTQAKTSYIGEEILWGYEFKNTLDHTSWKAGRFRVNYSHFDRVVPVDTPR 314 Query: 180 CSA 188 SA Sbjct: 315 VSA 317 >UniRef50_UPI0000D57724 Cluster: PREDICTED: similar to CG4370-PA, isoform A; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG4370-PA, isoform A - Tribolium castaneum Length = 395 Score = 52.4 bits (120), Expect = 1e-05 Identities = 22/74 (29%), Positives = 40/74 (54%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 + G S+ ++ SYL+ EI+WG+ FK Y K+K + ++ + ++ ++ PLC Sbjct: 291 MEGVSQTTSKMSHVTASYLNSEILWGHTFKPCTFYDKQKGCFVVNHKLFNSTREILMPLC 350 Query: 183 SACRLKDFEDNMKD 224 SA RL + + D Sbjct: 351 SARRLSQVREELAD 364 >UniRef50_UPI0000ECB8AB Cluster: ATP-sensitive inward rectifier potassium channel 11 (Potassium channel, inwardly rectifying subfamily J member 11) (Inward rectifier K(+) channel Kir6.2) (IKATP).; n=2; Gallus gallus|Rep: ATP-sensitive inward rectifier potassium channel 11 (Potassium channel, inwardly rectifying subfamily J member 11) (Inward rectifier K(+) channel Kir6.2) (IKATP). - Gallus gallus Length = 283 Score = 52.4 bits (120), Expect = 1e-05 Identities = 25/67 (37%), Positives = 40/67 (59%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G + G TQ+RTSYL+ EI+WG RF ++ ++E Y++D +V TP C Sbjct: 185 LEGVVETTGITTQARTSYLADEILWGQRFVPIV--AEEDGRYSVDYSKFGNTVKVPTPSC 242 Query: 183 SACRLKD 203 +A +L++ Sbjct: 243 TARQLEE 249 >UniRef50_Q15842 Cluster: ATP-sensitive inward rectifier potassium channel 8 (Potassium channel, inwardly rectifying subfamily J member 8) (Inwardly rectifier K(+) channel Kir6.1); n=60; Bilateria|Rep: ATP-sensitive inward rectifier potassium channel 8 (Potassium channel, inwardly rectifying subfamily J member 8) (Inwardly rectifier K(+) channel Kir6.1) - Homo sapiens (Human) Length = 424 Score = 52.4 bits (120), Expect = 1e-05 Identities = 31/107 (28%), Positives = 56/107 (52%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G + G TQ+RTSY+++EI WG+RF +++ ++E+ Y++D +V P C Sbjct: 296 LEGVVETTGITTQARTSYIAEEIQWGHRFVSIV--TEEEGVYSVDYSKFGNTVKVAAPRC 353 Query: 183 SACRLKDFEDNMKDSNTPTVLTQQCPFRQQTYL*ARRTLPQYLNSAI 323 SA L + + + + L+ Q R++ + RR N++I Sbjct: 354 SARELDEKPSILIQTLQKSELSHQNSLRKRNSM--RRNNSMRRNNSI 398 >UniRef50_A7RUM3 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 320 Score = 52.0 bits (119), Expect = 2e-05 Identities = 27/66 (40%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKE-AYAIDIENLDTVEQVETPL 179 L G ++ G TQ+RTSY++ EI WG+ F ++ Y K AY ID V+TP Sbjct: 254 LEGIVESTGMTTQARTSYIADEIHWGHNFTELVTYDCFKNGAYHIDFSRFHDTYPVDTPR 313 Query: 180 CSACRL 197 CSA L Sbjct: 314 CSAREL 319 >UniRef50_Q4SEH7 Cluster: Chromosome undetermined SCAF14620, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF14620, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 312 Score = 50.0 bits (114), Expect = 6e-05 Identities = 23/63 (36%), Positives = 36/63 (57%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G++++ + Q RTS++ +EI+WGY F ++ SKE Y +D N V V T C Sbjct: 223 LDGTAESTSSSCQVRTSFIPQEIMWGYNFLPIISRSKEGR-YRVDFSNFSKVVPVATAHC 281 Query: 183 SAC 191 + C Sbjct: 282 AYC 284 >UniRef50_P48050 Cluster: Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3); n=94; Euteleostomi|Rep: Inward rectifier potassium channel 4 (Potassium channel, inwardly rectifying subfamily J member 4) (Inward rectifier K(+) channel Kir2.3) - Homo sapiens (Human) Length = 445 Score = 50.0 bits (114), Expect = 6e-05 Identities = 27/68 (39%), Positives = 39/68 (57%), Gaps = 1/68 (1%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENL-DTVEQVETPL 179 L G + TQ+R+SYL+ EI+WG+RF+ V+ +EK Y +D T E TP Sbjct: 290 LEGMVEATAMTTQARSSYLASEILWGHRFEPVV--FEEKSHYKVDYSRFHKTYEVAGTPC 347 Query: 180 CSACRLKD 203 CSA L++ Sbjct: 348 CSARELQE 355 >UniRef50_Q969A5 Cluster: G-protein coupled inwardly rectifying potassium channel-B; n=1; Halocynthia roretzi|Rep: G-protein coupled inwardly rectifying potassium channel-B - Halocynthia roretzi (Sea squirt) Length = 399 Score = 48.0 bits (109), Expect = 3e-04 Identities = 25/77 (32%), Positives = 44/77 (57%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G ++ G + Q+RTSYL+ E++WG+RF VL ++++ +++D T +V P Sbjct: 312 LEGMIESTGMICQARTSYLNTEVLWGHRFMPVLFHARDH--FSVDHSEFHTTYEVPMPKQ 369 Query: 183 SACRLKDFEDNMKDSNT 233 S ++ F D +NT Sbjct: 370 S---MRRFHDAQVQNNT 383 >UniRef50_UPI00005873FD Cluster: PREDICTED: hypothetical protein; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 496 Score = 47.6 bits (108), Expect = 3e-04 Identities = 24/67 (35%), Positives = 37/67 (55%), Gaps = 1/67 (1%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVET-PL 179 + G + G V Q+RTSYL EI+WG RF + L E + +D + ++ V++ P Sbjct: 327 MEGVLEQTGLVMQARTSYLPSEILWGQRFSSNLISINNNEQFKVDYTDFNSTYAVQSMPS 386 Query: 180 CSACRLK 200 CSA L+ Sbjct: 387 CSAADLE 393 >UniRef50_Q9NPI9 Cluster: Inward rectifier potassium channel 16 (Potassium channel, inwardly rectifying subfamily J member 16) (Inward rectifier K(+) channel Kir5.1); n=23; Tetrapoda|Rep: Inward rectifier potassium channel 16 (Potassium channel, inwardly rectifying subfamily J member 16) (Inward rectifier K(+) channel Kir5.1) - Homo sapiens (Human) Length = 418 Score = 46.8 bits (106), Expect = 6e-04 Identities = 27/84 (32%), Positives = 46/84 (54%) Frame = +3 Query: 6 TGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLCS 185 TG S G QSR+SY+ +EI+WG+RF +VL+ +++ Y ++ + +V P CS Sbjct: 285 TGDST--GTSHQSRSSYVPREILWGHRFNDVLEV--KRKYYKVNCLQFEGSVEVYAPFCS 340 Query: 186 ACRLKDFEDNMKDSNTPTVLTQQC 257 A +L D++D + + C Sbjct: 341 AKQL-DWKDQQLHIEKAPPVRESC 363 >UniRef50_P48051 Cluster: G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2); n=98; Euteleostomi|Rep: G protein-activated inward rectifier potassium channel 2 (GIRK2) (Potassium channel, inwardly rectifying subfamily J member 6) (Inward rectifier K(+) channel Kir3.2) - Homo sapiens (Human) Length = 423 Score = 45.6 bits (103), Expect = 0.001 Identities = 24/67 (35%), Positives = 35/67 (52%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G + G Q+R+SY++ EI+WGYRF VL + E Y +D + + TP Sbjct: 308 LEGMVEATGMTCQARSSYITSEILWGYRFTPVL--TLEDGFYEVDYNSFHETYETSTPSL 365 Query: 183 SACRLKD 203 SA L + Sbjct: 366 SAKELAE 372 >UniRef50_UPI0000F1FEA6 Cluster: PREDICTED: similar to G protein-coupled inwardly rectifying potassium channel Kir3.4; n=2; Danio rerio|Rep: PREDICTED: similar to G protein-coupled inwardly rectifying potassium channel Kir3.4 - Danio rerio Length = 535 Score = 44.8 bits (101), Expect = 0.002 Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 3/77 (3%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G + G + Q++TSY+ EI WG RF+ + + EK ++ +D+ + V P C Sbjct: 419 LEGIVEATGMMCQAKTSYIETEIEWGARFEPCM--TLEKGSFRVDLRRFHSTYPVPLPPC 476 Query: 183 SA---CRLKDFEDNMKD 224 SA L + +D++KD Sbjct: 477 SAQDTHHLLELQDSLKD 493 >UniRef50_Q1IM86 Cluster: K+ channel, inward rectifier; n=1; Acidobacteria bacterium Ellin345|Rep: K+ channel, inward rectifier - Acidobacteria bacterium (strain Ellin345) Length = 311 Score = 44.0 bits (99), Expect = 0.004 Identities = 21/57 (36%), Positives = 33/57 (57%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVET 173 LT + + + SRTSY + E+IW RF N+ + +EK + D E LD VE++ + Sbjct: 257 LTATDEVFATIVHSRTSYSASEVIWDARFSNM--FVEEKGELSFDPEKLDAVEKLRS 311 >UniRef50_P78508 Cluster: ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2); n=60; Euteleostomi|Rep: ATP-sensitive inward rectifier potassium channel 10 (Potassium channel, inwardly rectifying subfamily J member 10) (Inward rectifier K(+) channel Kir1.2) - Homo sapiens (Human) Length = 379 Score = 44.0 bits (99), Expect = 0.004 Identities = 22/58 (37%), Positives = 32/58 (55%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETP 176 L+G+ ++ A Q RTSYL +EI+WGY F + S + Y D D V +V +P Sbjct: 283 LSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGK-YIADFSLFDQVVKVASP 339 >UniRef50_UPI000058708F Cluster: PREDICTED: similar to Inward rectifying k (potassium) channel family protein 2; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Inward rectifying k (potassium) channel family protein 2 - Strongylocentrotus purpuratus Length = 444 Score = 43.6 bits (98), Expect = 0.005 Identities = 17/33 (51%), Positives = 25/33 (75%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVL 101 L G ++ G TQ+RTSYL +EI+WGY F+N++ Sbjct: 331 LEGIVESTGTTTQARTSYLPQEIMWGYDFENII 363 >UniRef50_Q8R1Z6 Cluster: Kcnj14 protein; n=4; Eutheria|Rep: Kcnj14 protein - Mus musculus (Mouse) Length = 195 Score = 43.6 bits (98), Expect = 0.005 Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 4/89 (4%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLD-TVEQVETPL 179 L G + TQ R+SYL E++WG+RF+ VL + Y +D + T E TP+ Sbjct: 62 LEGMVEATAMTTQCRSSYLPGELLWGHRFEPVL--FQRGSQYEVDYRHFHRTYEVPGTPV 119 Query: 180 CSACRLKDFED---NMKDSNTPTVLTQQC 257 CSA L + + + S+ P LT C Sbjct: 120 CSAKELDERAEQASHSPKSSFPGSLTAFC 148 >UniRef50_A7S217 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 317 Score = 43.6 bits (98), Expect = 0.005 Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 1/63 (1%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRF-KNVLKYSKEKEAYAIDIENLDTVEQVETPL 179 L G + G VTQ R SYLS E+ WG+ F +LK + + ID D TP Sbjct: 253 LEGVVEATGMVTQGRASYLSSEVHWGHDFYPLMLKAADTPDRLEIDFSLFDHTYASSTPT 312 Query: 180 CSA 188 CSA Sbjct: 313 CSA 315 >UniRef50_A7SH65 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 307 Score = 43.2 bits (97), Expect = 0.007 Identities = 23/59 (38%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSK-EKEAYAIDIENLDTVEQVETP 176 L G + G TQ +TSYLS+EI+WG+ F V S + + YA D D +++V P Sbjct: 223 LDGIVEATGMNTQPKTSYLSQEILWGHDFLQVADQSPFDVQYYASDYSKFDDMKKVAMP 281 >UniRef50_O08871 Cluster: G-protein coupled inward rectifier potassium channel splice variant Kir3.1b; n=3; Euteleostomi|Rep: G-protein coupled inward rectifier potassium channel splice variant Kir3.1b - Rattus norvegicus (Rat) Length = 117 Score = 41.5 bits (93), Expect = 0.022 Identities = 20/56 (35%), Positives = 30/56 (53%) Frame = +3 Query: 9 GSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETP 176 G + MG Q+RTSY E++WG+RF V+ S E+ + +D +V TP Sbjct: 21 GGKRWMGMTCQARTSYTEDEVLWGHRFFPVI--SLEEGFFKVDYSQFHATFEVPTP 74 >UniRef50_Q969A6 Cluster: G-protein coupled inwardly rectifying potassium channel-A; n=1; Halocynthia roretzi|Rep: G-protein coupled inwardly rectifying potassium channel-A - Halocynthia roretzi (Sea squirt) Length = 612 Score = 41.5 bits (93), Expect = 0.022 Identities = 21/62 (33%), Positives = 32/62 (51%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L G + G Q+R+SY+ E++WG RF VL EK + ++ N +V +P Sbjct: 324 LEGMVEATGMTCQARSSYVEDEVLWGQRFMQVLML--EKGYFEVNYNNFHDTFEVSSPTA 381 Query: 183 SA 188 SA Sbjct: 382 SA 383 >UniRef50_UPI00005A5397 Cluster: PREDICTED: similar to potassium inwardly-rectifying channel J15 isoform 4; n=1; Canis lupus familiaris|Rep: PREDICTED: similar to potassium inwardly-rectifying channel J15 isoform 4 - Canis familiaris Length = 338 Score = 41.1 bits (92), Expect = 0.029 Identities = 21/61 (34%), Positives = 34/61 (55%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L + ++ AV QSRTSY+ +EI WG+ F V+ SK + Y D + + ++P C Sbjct: 246 LNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK-YVADFSQFEQIR--KSPDC 302 Query: 183 S 185 + Sbjct: 303 T 303 >UniRef50_Q93849 Cluster: Putative uncharacterized protein irk-3; n=2; Caenorhabditis|Rep: Putative uncharacterized protein irk-3 - Caenorhabditis elegans Length = 374 Score = 41.1 bits (92), Expect = 0.029 Identities = 17/47 (36%), Positives = 28/47 (59%) Frame = +3 Query: 27 GAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQV 167 G Q+RTS+L EI+WGY+FK ++ +++ Y + D E+V Sbjct: 303 GMTFQARTSFLPDEILWGYKFKPMVLMNEKLSKYEVHYSFFDQTERV 349 >UniRef50_UPI000155C4DF Cluster: PREDICTED: similar to inwardly rectifying potassium channel Kir4.2a; n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to inwardly rectifying potassium channel Kir4.2a - Ornithorhynchus anatinus Length = 569 Score = 40.3 bits (90), Expect = 0.050 Identities = 21/61 (34%), Positives = 34/61 (55%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETPLC 182 L + ++ AV QSRTSY+ +EI WG+ F V+ SK + Y D + + + +P C Sbjct: 477 LNATVESTSAVCQSRTSYIPEEIHWGFEFVPVVSLSKNGK-YVADFSQFEQIRR--SPDC 533 Query: 183 S 185 + Sbjct: 534 T 534 >UniRef50_Q4RG50 Cluster: Chromosome 2 SCAF15106, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 2 SCAF15106, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 499 Score = 40.3 bits (90), Expect = 0.050 Identities = 20/58 (34%), Positives = 30/58 (51%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETP 176 L G + G Q+RTSY E++WG+RF V+ S E+ + +D +V TP Sbjct: 330 LEGIVETTGMTCQARTSYTEDEVLWGHRFLPVM--SLEEGFFRVDYSQFHNTFEVPTP 385 >UniRef50_P48549 Cluster: G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1); n=41; Euteleostomi|Rep: G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1) - Homo sapiens (Human) Length = 501 Score = 39.9 bits (89), Expect = 0.067 Identities = 20/58 (34%), Positives = 30/58 (51%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETP 176 L G + G Q+RTSY E++WG+RF V+ S E+ + +D +V TP Sbjct: 299 LEGIVETTGMTCQARTSYTEDEVLWGHRFFPVI--SLEEGFFKVDYSQFHATFEVPTP 354 >UniRef50_UPI0000EB0168 Cluster: G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1).; n=1; Canis lupus familiaris|Rep: G protein-activated inward rectifier potassium channel 1 (GIRK1) (Potassium channel, inwardly rectifying subfamily J member 3) (Inward rectifier K(+) channel Kir3.1). - Canis familiaris Length = 111 Score = 38.3 bits (85), Expect = 0.20 Identities = 18/51 (35%), Positives = 28/51 (54%) Frame = +3 Query: 24 MGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETP 176 +G Q+RTSY E++WG+RF V+ S E+ + +D +V TP Sbjct: 24 VGMTCQARTSYTEDEVLWGHRFFPVI--SLEEGFFKVDYSQFHATFEVPTP 72 >UniRef50_Q4SN97 Cluster: Chromosome 8 SCAF14543, whole genome shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 8 SCAF14543, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 535 Score = 38.3 bits (85), Expect = 0.20 Identities = 20/57 (35%), Positives = 31/57 (54%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVET 173 L G + TQ R+SY++ EI+WG+RF+ VL + KE Y + + T + T Sbjct: 414 LEGMVEATAMTTQCRSSYVASEILWGHRFEPVL--FERKECYQVRKAEIGTCSRWTT 468 >UniRef50_UPI0000586212 Cluster: PREDICTED: similar to BIK; Kir2.1; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to BIK; Kir2.1 - Strongylocentrotus purpuratus Length = 532 Score = 37.1 bits (82), Expect = 0.47 Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 3/86 (3%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRF-KNVLKYSKE-KEAYAIDIENLDTVEQVE-T 173 L G + G TQ+RTSY+ EI WG RF +VL E + Y ID + V Sbjct: 331 LEGIVEQTGLTTQARTSYMPGEIQWGSRFCSSVLCLRSEFDKQYDIDYSKFEETYTVPGH 390 Query: 174 PLCSACRLKDFEDNMKDSNTPTVLTQ 251 P SA L + E ++ T + L Q Sbjct: 391 PRKSAKELDEIEQK-EEETTESQLAQ 415 >UniRef50_A6H129 Cluster: Inward rectifier potassium channel Irk; n=1; Flavobacterium psychrophilum JIP02/86|Rep: Inward rectifier potassium channel Irk - Flavobacterium psychrophilum (strain JIP02/86 / ATCC 49511) Length = 318 Score = 36.7 bits (81), Expect = 0.62 Identities = 15/41 (36%), Positives = 26/41 (63%) Frame = +3 Query: 45 RTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQV 167 RTSY+ KEI++G +F + K+S + I I+ L+ E++ Sbjct: 276 RTSYIFKEIVYGAKFLQMFKHSNDNTKTIIHIDKLNLFEEI 316 >UniRef50_Q2JL46 Cluster: Putative uncharacterized protein; n=1; Synechococcus sp. JA-2-3B'a(2-13)|Rep: Putative uncharacterized protein - Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone B-Prime) Length = 80 Score = 36.3 bits (80), Expect = 0.82 Identities = 17/58 (29%), Positives = 26/58 (44%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETP 176 LTG +R SYL+ EI+W +RF ++L Y +D + T + P Sbjct: 16 LTGIDDTFSQTIHARHSYLADEILWNHRFADILHLDSNGHRY-VDYSHFHTTLPAQAP 72 >UniRef50_A6RBQ6 Cluster: Predicted protein; n=1; Ajellomyces capsulatus NAm1|Rep: Predicted protein - Ajellomyces capsulatus NAm1 Length = 1288 Score = 35.5 bits (78), Expect = 1.4 Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 1/88 (1%) Frame = +2 Query: 116 KGSLCD*H*KPGYRGTSRDAALQRLPSQGFRR*HERLKHPNRLDPTMS-ISPTDLSLSQE 292 K + C H K R + R + LP+ + E++ H LDP M+ I+ D+ +S + Sbjct: 1152 KPAHCPNHRKSKKRRSLRLSGQPALPALSVEQSDEQMAHQMSLDPEMAKITAADVEMSNQ 1211 Query: 293 DSSTISKLGDSLPSSPTLNRTATQRSFG 376 ISK GD S+ R+ + G Sbjct: 1212 TDHPISKEGDLAGSTEQETRSGKPETSG 1239 >UniRef50_A7HIG5 Cluster: K channel inward rectifier conserved region 2 domain protein; n=2; Anaeromyxobacter|Rep: K channel inward rectifier conserved region 2 domain protein - Anaeromyxobacter sp. Fw109-5 Length = 299 Score = 34.3 bits (75), Expect = 3.3 Identities = 15/58 (25%), Positives = 31/58 (53%) Frame = +3 Query: 3 LTGSSKNMGAVTQSRTSYLSKEIIWGYRFKNVLKYSKEKEAYAIDIENLDTVEQVETP 176 L+G + + V +R +YL +++ W RF++++K + +A+D V +E P Sbjct: 233 LSGFDEGLSRVIHARRTYLPEDLRWEARFRDIVKVLPRGD-HAVDYRRFHEVTAIEPP 289 >UniRef50_Q23K61 Cluster: HECT domain and RCC1-like domain-containing protein; n=3; cellular organisms|Rep: HECT domain and RCC1-like domain-containing protein - Tetrahymena thermophila SB210 Length = 5350 Score = 33.9 bits (74), Expect = 4.4 Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 2/58 (3%) Frame = +3 Query: 6 TGSSKNM-GAVTQSRTSYLSKEIIWGYRFKNV-LKYSKEKEAYAIDIENLDTVEQVET 173 TG++ + G V S+ +EI W Y ++ L+ S ++++ IDI N DT+EQV+T Sbjct: 381 TGNNNTIPGKVYASQQVSKQEEICWTYLKGSLYLRTSTKEQSGLIDIYNCDTLEQVDT 438 >UniRef50_UPI0000D57723 Cluster: PREDICTED: similar to Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1) (RBL-IRK1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Inward rectifier potassium channel 2 (Potassium channel, inwardly rectifying subfamily J member 2) (Inward rectifier K(+) channel Kir2.1) (RBL-IRK1) - Tribolium castaneum Length = 329 Score = 33.5 bits (73), Expect = 5.8 Identities = 13/27 (48%), Positives = 19/27 (70%) Frame = +3 Query: 9 GSSKNMGAVTQSRTSYLSKEIIWGYRF 89 G S G +Q+RTSY + +I+WG+RF Sbjct: 283 GLSVITGQASQNRTSYTNSDILWGHRF 309 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 734,984,506 Number of Sequences: 1657284 Number of extensions: 14539984 Number of successful extensions: 36311 Number of sequences better than 10.0: 47 Number of HSP's better than 10.0 without gapping: 35083 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 36295 length of database: 575,637,011 effective HSP length: 99 effective length of database: 411,565,895 effective search space used: 62969581935 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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