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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= pg--0335.Seq
         (768 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P40320 Cluster: S-adenosylmethionine synthetase; n=19; ...   149   7e-35
UniRef50_Q00266 Cluster: S-adenosylmethionine synthetase isoform...   123   4e-27
UniRef50_P19358 Cluster: S-adenosylmethionine synthetase 2; n=65...   100   8e-20
UniRef50_Q837P9 Cluster: S-adenosylmethionine synthetase; n=45; ...    95   1e-18
UniRef50_Q9K7Q9 Cluster: S-adenosylmethionine synthetase; n=65; ...    95   1e-18
UniRef50_Q1GND0 Cluster: S-adenosylmethionine synthetase; n=29; ...    91   2e-17
UniRef50_P0A820 Cluster: S-adenosylmethionine synthetase; n=23; ...    91   3e-17
UniRef50_P72871 Cluster: S-adenosylmethionine synthetase; n=119;...    89   1e-16
UniRef50_Q2U8T6 Cluster: S-adenosylmethionine synthetase; n=2; A...    88   3e-16
UniRef50_Q650L4 Cluster: S-adenosylmethionine synthetase; n=19; ...    87   6e-16
UniRef50_Q661P3 Cluster: S-adenosylmethionine synthetase; n=3; B...    85   2e-15
UniRef50_Q4A5F4 Cluster: S-adenosylmethionine synthetase; n=4; B...    83   6e-15
UniRef50_Q7QWJ4 Cluster: S-adenosylmethionine synthetase; n=1; G...    82   2e-14
UniRef50_Q7NB16 Cluster: S-adenosylmethionine synthetase; n=2; M...    81   2e-14
UniRef50_A7APP7 Cluster: S-adenosylmethionine synthetase, putati...    81   2e-14
UniRef50_Q6KHY1 Cluster: S-adenosylmethionine synthetase; n=7; M...    80   5e-14
UniRef50_Q2GDS4 Cluster: S-adenosylmethionine synthetase; n=1; N...    79   9e-14
UniRef50_O09486 Cluster: S-adenosylmethionine synthetase; n=1; A...    79   9e-14
UniRef50_UPI00015BD1C2 Cluster: UPI00015BD1C2 related cluster; n...    79   2e-13
UniRef50_Q6A7D8 Cluster: S-adenosylmethionine synthetase; n=11; ...    78   3e-13
UniRef50_Q6SZ22 Cluster: S-adenosylmethionine synthetase; n=4; S...    77   5e-13
UniRef50_A6QA94 Cluster: S-adenosylmethionine synthetase; n=20; ...    77   6e-13
UniRef50_A6BGC6 Cluster: S-adenosylmethionine synthetase; n=1; D...    77   6e-13
UniRef50_A5BU08 Cluster: Putative uncharacterized protein; n=1; ...    77   6e-13
UniRef50_P78003 Cluster: S-adenosylmethionine synthetase; n=4; M...    76   1e-12
UniRef50_Q5EK82 Cluster: S-adenosyl methionine synthetase 2; n=6...    75   2e-12
UniRef50_Q1VNA9 Cluster: S-adenosylmethionine synthetase; n=1; P...    73   8e-12
UniRef50_Q5FGR4 Cluster: S-adenosylmethionine synthetase; n=13; ...    72   1e-11
UniRef50_UPI000039A2E5 Cluster: COG0192: S-adenosylmethionine sy...    71   2e-11
UniRef50_A7Q4X0 Cluster: Chromosome undetermined scaffold_51, wh...    70   6e-11
UniRef50_A5AMB5 Cluster: Putative uncharacterized protein; n=1; ...    69   2e-10
UniRef50_A4QEH8 Cluster: Putative uncharacterized protein; n=1; ...    64   5e-09
UniRef50_Q027Y1 Cluster: Methionine adenosyltransferase; n=1; So...    61   3e-08
UniRef50_Q60BL6 Cluster: S-adenosylmethionine synthetase; n=6; B...    59   1e-07
UniRef50_Q0GGP1 Cluster: S-adenosylmethionine synthetase; n=2; A...    56   1e-06
UniRef50_Q0JN66 Cluster: Os01g0323600 protein; n=1; Oryza sativa...    52   2e-05
UniRef50_A7NSM8 Cluster: Chromosome chr18 scaffold_1, whole geno...    51   3e-05
UniRef50_Q9S992 Cluster: MET adenosyltransferase homolog; n=3; c...    47   4e-04
UniRef50_Q2LSR0 Cluster: S-adenosylmethionine synthetase; n=1; S...    46   0.001
UniRef50_Q42242 Cluster: S-adenosyl methionine synthase; n=5; Eu...    44   0.004
UniRef50_A6PKG8 Cluster: Methionine adenosyltransferase precurso...    43   0.010
UniRef50_Q09A96 Cluster: Putative uncharacterized protein; n=1; ...    38   0.21 
UniRef50_A2Y188 Cluster: Putative uncharacterized protein; n=1; ...    36   0.84 
UniRef50_Q6MA58 Cluster: Putative uncharacterized protein; n=1; ...    36   1.5  
UniRef50_Q8MU02 Cluster: Putative S-adenosylmethionine synthetas...    35   1.9  
UniRef50_A0U6S4 Cluster: Putative uncharacterized protein precur...    35   2.6  

>UniRef50_P40320 Cluster: S-adenosylmethionine synthetase; n=19;
           Eukaryota|Rep: S-adenosylmethionine synthetase -
           Drosophila melanogaster (Fruit fly)
          Length = 408

 Score =  149 bits (361), Expect = 7e-35
 Identities = 67/85 (78%), Positives = 77/85 (90%)
 Frame = +1

Query: 1   EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVS 180
           EECMPLTVVLAHKLN+KIAELRR+  FWWARPDSKTQVTCEY+F  G+ VP+RVHT+VVS
Sbjct: 158 EECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAVPKRVHTIVVS 217

Query: 181 LQHSEKITLETLRDEIREKVIKEVI 255
           +QHSEKI+LETLR E+ EKV+K VI
Sbjct: 218 MQHSEKISLETLRSEVMEKVVKVVI 242



 Score =  140 bits (340), Expect = 3e-32
 Identities = 62/80 (77%), Positives = 73/80 (91%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTST 688
           QV+YAI +AEPLSITVFDYGTSHK+Q++LL I+++NFDLRPGKIVK+LNLR PIYQRTST
Sbjct: 328 QVSYAIGLAEPLSITVFDYGTSHKSQKELLDIIRRNFDLRPGKIVKDLNLRQPIYQRTST 387

Query: 689 YGHFGRAGFPWEIPKPLIVE 748
           YGHFGRAGF WE  KPL ++
Sbjct: 388 YGHFGRAGFSWEEAKPLEID 407



 Score =  123 bits (296), Expect = 6e-27
 Identities = 56/78 (71%), Positives = 61/78 (78%)
 Frame = +3

Query: 255 PAQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVD 434
           PA+Y+D  T++HINPCGLF+IGGP  DAGLTGRKIIVDTY             KDFTKVD
Sbjct: 243 PAKYIDANTIVHINPCGLFVIGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDFTKVD 302

Query: 435 RSAAYAARWVAKSLVKAG 488
           RSAAYAARWVAKSLVKAG
Sbjct: 303 RSAAYAARWVAKSLVKAG 320


>UniRef50_Q00266 Cluster: S-adenosylmethionine synthetase isoform
           type-1; n=171; cellular organisms|Rep:
           S-adenosylmethionine synthetase isoform type-1 - Homo
           sapiens (Human)
          Length = 395

 Score =  123 bits (297), Expect = 4e-27
 Identities = 51/78 (65%), Positives = 68/78 (87%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTST 688
           QV+YAI VAEPLSI++F YGTS KT+++LL +V KNFDLRPG IV++L+L+ PIYQ+T+ 
Sbjct: 317 QVSYAIGVAEPLSISIFTYGTSQKTERELLDVVHKNFDLRPGVIVRDLDLKKPIYQKTAC 376

Query: 689 YGHFGRAGFPWEIPKPLI 742
           YGHFGR+ FPWE+P+ L+
Sbjct: 377 YGHFGRSEFPWEVPRKLV 394



 Score =  116 bits (278), Expect = 9e-25
 Identities = 49/85 (57%), Positives = 69/85 (81%)
 Frame = +1

Query: 1   EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVS 180
           EECMPLT++LAHKLN ++A+LRR+G   W RPDSKTQVT +Y+   GA +P R+HT+V+S
Sbjct: 147 EECMPLTIILAHKLNARMADLRRSGLLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVIS 206

Query: 181 LQHSEKITLETLRDEIREKVIKEVI 255
           +QH+E ITLE +R  ++E+VI+ V+
Sbjct: 207 VQHNEDITLEEMRRALKEQVIRAVV 231



 Score =  114 bits (274), Expect = 3e-24
 Identities = 54/78 (69%), Positives = 59/78 (75%)
 Frame = +3

Query: 255 PAQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVD 434
           PA+YLDE TV H+ P G F+IGGPQ DAG+TGRKIIVDTY             KD+TKVD
Sbjct: 232 PAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYGGWGAHGGGAFSGKDYTKVD 291

Query: 435 RSAAYAARWVAKSLVKAG 488
           RSAAYAARWVAKSLVKAG
Sbjct: 292 RSAAYAARWVAKSLVKAG 309


>UniRef50_P19358 Cluster: S-adenosylmethionine synthetase 2; n=659;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           2 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 384

 Score = 99.5 bits (237), Expect = 8e-20
 Identities = 49/78 (62%), Positives = 52/78 (66%)
 Frame = +3

Query: 255 PAQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVD 434
           P   LDE T   I P G F+IGGPQ DAGLTGRKIIVD Y             KD++KVD
Sbjct: 221 PKDMLDENTKYFIQPSGRFVIGGPQGDAGLTGRKIIVDAYGGASSVGGGAFSGKDYSKVD 280

Query: 435 RSAAYAARWVAKSLVKAG 488
           RSAAYAARWVAKSLV AG
Sbjct: 281 RSAAYAARWVAKSLVAAG 298



 Score = 95.1 bits (226), Expect = 2e-18
 Identities = 43/85 (50%), Positives = 59/85 (69%)
 Frame = +2

Query: 485 GLVPVLHGQVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRA 664
           GL   +  Q +YAI +AEPLS+ V  YGT+ K+  +++ I++KNFDLRPG +VKEL+L  
Sbjct: 298 GLCKRVQVQFSYAIGIAEPLSLHVDTYGTATKSDDEIIEIIKKNFDLRPGVLVKELDLAR 357

Query: 665 PIYQRTSTYGHFGRAGFPWEIPKPL 739
           PIY  T++YGHF    + WE PK L
Sbjct: 358 PIYLPTASYGHFTNQEYSWEKPKKL 382



 Score = 93.1 bits (221), Expect = 7e-18
 Identities = 41/89 (46%), Positives = 65/89 (73%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSL 183
           E +PLT++LAHKLN  +A+ RR+G   W RPD+KTQVT EY    G  VP+R+ TVV+S 
Sbjct: 137 EGLPLTILLAHKLNMAMADARRDGSLPWLRPDTKTQVTVEYEDDNGRWVPKRIDTVVISA 196

Query: 184 QHSEKITLETLRDEIREKVIKEVILHNIL 270
           QH+++I+   LR ++++ ++++VI  ++L
Sbjct: 197 QHADEISTADLRTQLQKDIVEKVIPKDML 225


>UniRef50_Q837P9 Cluster: S-adenosylmethionine synthetase; n=45;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           - Enterococcus faecalis (Streptococcus faecalis)
          Length = 394

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 46/78 (58%), Positives = 54/78 (69%)
 Frame = +3

Query: 255 PAQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVD 434
           P + LD+ T   INP G F+IGGPQ DAGLTGRKIIVDTY             KD TKVD
Sbjct: 222 PHELLDDETKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVD 281

Query: 435 RSAAYAARWVAKSLVKAG 488
           RSA+YAAR++AK++V AG
Sbjct: 282 RSASYAARYIAKNIVAAG 299



 Score = 89.4 bits (212), Expect = 8e-17
 Identities = 41/82 (50%), Positives = 58/82 (70%), Gaps = 2/82 (2%)
 Frame = +2

Query: 485 GLVPVLHGQVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRA 664
           GL   +  Q+AYAI VA+P+SI++  +GTS   + +L+  V+KNFDLRP  I++ L+LR 
Sbjct: 299 GLAKKVEVQLAYAIGVAQPVSISINTFGTSDLPESKLIEAVRKNFDLRPAGIIEMLDLRR 358

Query: 665 PIYQRTSTYGHFGRA--GFPWE 724
           PIY++T+ YGHFGR     PWE
Sbjct: 359 PIYKQTAAYGHFGRTDIDLPWE 380



 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 42/89 (47%), Positives = 61/89 (68%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSL 183
           E MPL + L+H+L +++AELR+     + RPD+K+QVT EY   G    PQRV T+V+S 
Sbjct: 141 ELMPLPIALSHRLVRRLAELRKEKVLPYLRPDAKSQVTVEYDDQGQ---PQRVDTIVIST 197

Query: 184 QHSEKITLETLRDEIREKVIKEVILHNIL 270
           QH ++ TLE +  +I+E+VI EVI H +L
Sbjct: 198 QHDDETTLEQIEKDIKEQVINEVIPHELL 226


>UniRef50_Q9K7Q9 Cluster: S-adenosylmethionine synthetase; n=65;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           - Bacillus halodurans
          Length = 399

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 47/78 (60%), Positives = 53/78 (67%)
 Frame = +3

Query: 255 PAQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVD 434
           P + +DE T   INP G F+IGGPQ DAGLTGRKIIVDTY             KD TKVD
Sbjct: 229 PEELIDEETKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVD 288

Query: 435 RSAAYAARWVAKSLVKAG 488
           RS AYAAR+VAK++V AG
Sbjct: 289 RSGAYAARYVAKNIVAAG 306



 Score = 86.2 bits (204), Expect = 8e-16
 Identities = 39/82 (47%), Positives = 58/82 (70%), Gaps = 2/82 (2%)
 Frame = +2

Query: 485 GLVPVLHGQVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRA 664
           GL      Q+AYAI VA+P+SI++  +GT   ++ +L+ +V+++FDLRP  I+K L+LR 
Sbjct: 306 GLADKCEVQLAYAIGVAKPVSISIDTFGTGQVSEARLVELVREHFDLRPAGIIKMLDLRR 365

Query: 665 PIYQRTSTYGHFGRAG--FPWE 724
           PIY++T+ YGHFGR     PWE
Sbjct: 366 PIYKQTAAYGHFGRTDVELPWE 387



 Score = 68.1 bits (159), Expect = 2e-10
 Identities = 33/92 (35%), Positives = 56/92 (60%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSL 183
           E MPL + L+HKL ++++E R+     + RPD KTQVT EY     +    R+ T+V+S 
Sbjct: 148 ELMPLPISLSHKLARRLSEARKGEILPYLRPDGKTQVTVEYDENDQSV---RIDTIVIST 204

Query: 184 QHSEKITLETLRDEIREKVIKEVILHNILMRE 279
           QH  ++TLE +  ++++ VI+ V+   ++  E
Sbjct: 205 QHHPEVTLEQIESDLKQHVIRSVVPEELIDEE 236


>UniRef50_Q1GND0 Cluster: S-adenosylmethionine synthetase; n=29;
           Alphaproteobacteria|Rep: S-adenosylmethionine synthetase
           - Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 406

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 46/78 (58%), Positives = 51/78 (65%)
 Frame = +3

Query: 255 PAQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVD 434
           PA+ L   TV HINP G F IGGP  DAGLTGRKIIVDTY             KD TKVD
Sbjct: 232 PAELLTANTVYHINPTGRFEIGGPDGDAGLTGRKIIVDTYGGASPHGGGAFSGKDPTKVD 291

Query: 435 RSAAYAARWVAKSLVKAG 488
           RSAAY  R++AK++V AG
Sbjct: 292 RSAAYITRYLAKNIVAAG 309



 Score = 62.5 bits (145), Expect = 1e-08
 Identities = 50/140 (35%), Positives = 68/140 (48%), Gaps = 11/140 (7%)
 Frame = +2

Query: 338 GPDGTQNHRGH---VWRVGGAR-RGRFLWQGLHQGRPLRS---IRRPMGRQVARQGGLVP 496
           GPDG     G    V   GGA   G   + G    +  RS   I R + + +    GL  
Sbjct: 254 GPDGDAGLTGRKIIVDTYGGASPHGGGAFSGKDPTKVDRSAAYITRYLAKNIVA-AGLAR 312

Query: 497 VLHGQVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQ 676
               Q++YAI VAEPLSI V  +GT    + ++ +++ +   L P  I   L L  PIY+
Sbjct: 313 RCTIQLSYAIGVAEPLSIYVDLHGTGTVDEGRIEAVLPQLVRLTPKGIRTHLGLNKPIYR 372

Query: 677 RTSTYGHFGRA----GFPWE 724
           +T+ YGHFGR      FPWE
Sbjct: 373 QTAAYGHFGRQADGDAFPWE 392



 Score = 36.7 bits (81), Expect = 0.63
 Identities = 21/61 (34%), Positives = 33/61 (54%)
 Frame = +1

Query: 10  MPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSLQH 189
           MP T+  +HK+ +++A  R+ G   +  PD+K+QVT  Y        P     +VVS QH
Sbjct: 145 MPATLDYSHKILERMASDRKAGIAPFLEPDAKSQVTLRY----ANERPVEATAIVVSTQH 200

Query: 190 S 192
           +
Sbjct: 201 A 201


>UniRef50_P0A820 Cluster: S-adenosylmethionine synthetase; n=23;
           Proteobacteria|Rep: S-adenosylmethionine synthetase -
           Shigella flexneri
          Length = 384

 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 45/78 (57%), Positives = 52/78 (66%)
 Frame = +3

Query: 255 PAQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVD 434
           PA++L   T   INP G F+IGGP  D GLTGRKIIVDTY             KD +KVD
Sbjct: 213 PAEWLTSATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVD 272

Query: 435 RSAAYAARWVAKSLVKAG 488
           RSAAYAAR+VAK++V AG
Sbjct: 273 RSAAYAARYVAKNIVAAG 290



 Score = 84.2 bits (199), Expect = 3e-15
 Identities = 50/117 (42%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
 Frame = +2

Query: 383 GGARRGRFLWQGLHQGRPLRSIRRPMGRQVARQ---GGLVPVLHGQVAYAISVAEPLSIT 553
           G AR G   + G    +  RS      R VA+     GL      QV+YAI VAEP SI 
Sbjct: 254 GMARHGGGAFSGKDPSKVDRSAAYA-ARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIM 312

Query: 554 VFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTSTYGHFGRAGFPWE 724
           V  +GT     +QL  +V++ FDLRP  +++ L+L  PIY+ T+ YGHFGR  FPWE
Sbjct: 313 VETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWE 369



 Score = 67.7 bits (158), Expect = 3e-10
 Identities = 34/82 (41%), Positives = 54/82 (65%)
 Frame = +1

Query: 10  MPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSLQH 189
           MP  +  AH+L Q+ AE+R+NG   W RPD+K+QVT +Y    G  V   +  VV+S QH
Sbjct: 135 MPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQY--DDGKIV--GIDAVVLSTQH 190

Query: 190 SEKITLETLRDEIREKVIKEVI 255
           SE+I  ++L++ + E++IK ++
Sbjct: 191 SEEIDQKSLQEAVMEEIIKPIL 212


>UniRef50_P72871 Cluster: S-adenosylmethionine synthetase; n=119;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Synechocystis sp. (strain PCC 6803)
          Length = 426

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 43/72 (59%), Positives = 51/72 (70%)
 Frame = +3

Query: 273 ERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYA 452
           ++T   +NP G F++GGPQ DAGLTGRKIIVDTY             KD TKVDRSAAYA
Sbjct: 246 DKTRFIVNPTGKFVVGGPQGDAGLTGRKIIVDTYGGYSRHGGGAFSGKDPTKVDRSAAYA 305

Query: 453 ARWVAKSLVKAG 488
           AR+VAK++V AG
Sbjct: 306 ARYVAKNIVAAG 317



 Score = 69.7 bits (163), Expect = 7e-11
 Identities = 37/89 (41%), Positives = 50/89 (56%), Gaps = 9/89 (10%)
 Frame = +2

Query: 485 GLVPVLHGQVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLR- 661
           GL      QV+YAI VA P+S+ +  +GT    +++LL +V  NF+LRP  I++ LNLR 
Sbjct: 317 GLADKCEVQVSYAIGVARPVSVLIDTFGTGKVDEEKLLEVVLANFELRPAGIIQSLNLRN 376

Query: 662 ------APIYQRTSTYGHFGR--AGFPWE 724
                    YQ  + YGHFGR     PWE
Sbjct: 377 LPAERGGRFYQDVAAYGHFGRNDLDLPWE 405



 Score = 56.8 bits (131), Expect = 6e-07
 Identities = 28/79 (35%), Positives = 50/79 (63%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSL 183
           E MPL + LAH++  +++E+R++G+  + RPD KTQV+   ++  G+  P  + T+++S 
Sbjct: 150 ELMPLPISLAHRIALRLSEVRKSGQLAYLRPDGKTQVS--ILYEDGS--PVAIDTILIST 205

Query: 184 QHSEKITLETLRDEIREKV 240
           QH E I   T  D ++ K+
Sbjct: 206 QHDEHIGDITDNDAVQAKI 224


>UniRef50_Q2U8T6 Cluster: S-adenosylmethionine synthetase; n=2;
           Ascomycota|Rep: S-adenosylmethionine synthetase -
           Aspergillus oryzae
          Length = 384

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 49/116 (42%), Positives = 66/116 (56%), Gaps = 6/116 (5%)
 Frame = +2

Query: 416 GLHQGRPLRSIRRP---MGRQVARQ---GGLVPVLHGQVAYAISVAEPLSITVFDYGTSH 577
           G   G+  R + R    M R +A+     GL      Q++Y+I +AEPLSI +  + TS 
Sbjct: 269 GAFSGKDFRQVDRSAAYMARWIAKSLVHHGLAHRCLIQLSYSIGIAEPLSIFIDTFKTSK 328

Query: 578 KTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTSTYGHFGRAGFPWEIPKPLIV 745
            T  QL  I++KNFDLRP  I K+LNL  PIY +T+  GHF    FPWE P  L++
Sbjct: 329 FTSDQLKEIIRKNFDLRPAAIAKDLNLIDPIYYQTAKNGHFTNEKFPWEQPLDLVL 384



 Score = 83.4 bits (197), Expect = 6e-15
 Identities = 41/82 (50%), Positives = 50/82 (60%)
 Frame = +3

Query: 243 QRGYPAQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDF 422
           ++  PA+YLD+RT  HI P G   +      AG+TGRKI+VDTY             KDF
Sbjct: 217 RKSIPAKYLDDRTAYHIQPTGDVGVSPSGKFAGVTGRKIVVDTYGGWGAHGGGAFSGKDF 276

Query: 423 TKVDRSAAYAARWVAKSLVKAG 488
            +VDRSAAY ARW+AKSLV  G
Sbjct: 277 RQVDRSAAYMARWIAKSLVHHG 298



 Score = 77.4 bits (182), Expect = 4e-13
 Identities = 36/84 (42%), Positives = 54/84 (64%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSL 183
           + +PLT+ LAH++++++     N    W RPD+K QVT EYV   G  VP RVH VV++ 
Sbjct: 137 QLLPLTLHLAHRISRELKAAHTNRILPWLRPDTKAQVTVEYVEDEGRMVPTRVHNVVITA 196

Query: 184 QHSEKITLETLRDEIREKVIKEVI 255
           QH+  + LE LR  I +KV+++ I
Sbjct: 197 QHTPGVPLEKLRQGILDKVVRKSI 220


>UniRef50_Q650L4 Cluster: S-adenosylmethionine synthetase; n=19;
           cellular organisms|Rep: S-adenosylmethionine synthetase
           - Bacteroides fragilis
          Length = 430

 Score = 86.6 bits (205), Expect = 6e-16
 Identities = 41/73 (56%), Positives = 49/73 (67%)
 Frame = +3

Query: 270 DERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAY 449
           ++  + H+NP G F+IGGP  D GLTGRKIIVDTY             KD +KVDRSAAY
Sbjct: 242 NDHIIYHVNPTGKFVIGGPHGDTGLTGRKIIVDTYGGKGAHGGGAFSGKDPSKVDRSAAY 301

Query: 450 AARWVAKSLVKAG 488
           AAR +AK+LV AG
Sbjct: 302 AARHIAKNLVAAG 314



 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 31/68 (45%), Positives = 41/68 (60%), Gaps = 2/68 (2%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSH--KTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRT 682
           QV+YAI VA P++I V  YG S+   +  ++   + + FDLRP  I   L LR PIY  T
Sbjct: 322 QVSYAIGVARPINIYVNTYGRSNVKMSDGEIARKIDELFDLRPKAIEDRLKLRYPIYSET 381

Query: 683 STYGHFGR 706
           + YGH GR
Sbjct: 382 AAYGHMGR 389



 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 32/68 (47%), Positives = 44/68 (64%), Gaps = 1/68 (1%)
 Frame = +1

Query: 1   EECMPLTVVLAHKLNQKIAELRRNG-EFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVV 177
           E  MPL++ LAH++   +A++RR G E  + RPD+K+QVT EY   G    P R+ T+VV
Sbjct: 131 ENYMPLSLDLAHRILLVLADIRREGKEMTYLRPDAKSQVTIEYDDNG---TPVRIDTIVV 187

Query: 178 SLQHSEKI 201
           S QH E I
Sbjct: 188 STQHDEFI 195


>UniRef50_Q661P3 Cluster: S-adenosylmethionine synthetase; n=3;
           Borrelia burgdorferi group|Rep: S-adenosylmethionine
           synthetase - Borrelia garinii
          Length = 392

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 41/74 (55%), Positives = 48/74 (64%)
 Frame = +3

Query: 267 LDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAA 446
           +DE T   INP G F+IGGP  D GLTGRKII D+Y             KD TKVDRSAA
Sbjct: 226 IDENTTYCINPSGNFVIGGPTGDTGLTGRKIIADSYGGFARHGGGAYSGKDATKVDRSAA 285

Query: 447 YAARWVAKSLVKAG 488
           Y AR++AK++V AG
Sbjct: 286 YMARYIAKNMVAAG 299



 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 40/117 (34%), Positives = 59/117 (50%), Gaps = 3/117 (2%)
 Frame = +2

Query: 383 GGARRGRFLWQGLHQGRPLRSIRRPMGRQVARQ---GGLVPVLHGQVAYAISVAEPLSIT 553
           G AR G   + G    +  RS    M R +A+     G+      Q+AYAI +  P+SI 
Sbjct: 263 GFARHGGGAYSGKDATKVDRSAAY-MARYIAKNMVAAGISKEFELQLAYAIGIENPISIQ 321

Query: 554 VFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTSTYGHFGRAGFPWE 724
           +       K   ++L+ +  NFDL P  I+++L L+ PIY +T TYG  G+  F WE
Sbjct: 322 ITSGINDPKYANKILNFIVNNFDLTPNGIIEKLKLKQPIYLKTCTYGQLGKNEFEWE 378



 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 31/90 (34%), Positives = 51/90 (56%)
 Frame = +1

Query: 10  MPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSLQH 189
           +P    LA+ + +K + LR++G   W RPDSK+QVT EY        P ++  ++VS QH
Sbjct: 142 LPAPYELANSILKKASNLRKSGAIEWLRPDSKSQVTIEY---DKNRRPVKIKNIIVSHQH 198

Query: 190 SEKITLETLRDEIREKVIKEVILHNILMRE 279
              I+ + +R+ I E++IK  I    ++ E
Sbjct: 199 HPNISQKLIREPIIEEIIKPTIQDKSIIDE 228


>UniRef50_Q4A5F4 Cluster: S-adenosylmethionine synthetase; n=4;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Mycoplasma synoviae (strain 53)
          Length = 382

 Score = 83.4 bits (197), Expect = 6e-15
 Identities = 41/67 (61%), Positives = 45/67 (67%)
 Frame = +3

Query: 285 IHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWV 464
           I INP G F+IGGP SD GLTGRKIIVDTY             KD TK+DRS AY ARW+
Sbjct: 215 ILINPTGKFVIGGPFSDTGLTGRKIIVDTYGGSARHGGGAFSGKDATKLDRSGAYMARWI 274

Query: 465 AKSLVKA 485
           AK+LV A
Sbjct: 275 AKNLVAA 281



 Score = 76.2 bits (179), Expect = 8e-13
 Identities = 44/119 (36%), Positives = 64/119 (53%), Gaps = 5/119 (4%)
 Frame = +2

Query: 383 GGARRGRFLWQGLHQGRPLRSIRRPMGRQVARQ---GGLVPVLHGQVAYAISVAEPLSIT 553
           G AR G   + G    +  RS    M R +A+      +   +  Q+AY+I VA+P+S+ 
Sbjct: 246 GSARHGGGAFSGKDATKLDRS-GAYMARWIAKNLVAANIADKIEVQIAYSIGVAKPVSVM 304

Query: 554 VFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTSTYGHFGRAG--FPWE 724
           V  +G +   +  +L  +  NF+L P  I+K LNL  PIYQ++S YGHFGR    F WE
Sbjct: 305 VNTFGENKVPEDVVLDAILNNFELTPKGIIKSLNLNKPIYQKSSVYGHFGREDFQFTWE 363



 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 28/84 (33%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
 Frame = +1

Query: 10  MPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQ--RVHTVVVSL 183
           MPL + L +K+  +   L +N EF  A+ D KTQVT +Y      + PQ  +V T++ S 
Sbjct: 127 MPLGITLCNKIVSRAGMLIKNQEFKDAKEDMKTQVTLDY------SDPQNVKVDTIIFSC 180

Query: 184 QHSEKITLETLRDEIREKVIKEVI 255
            H+EK      ++ I+ +++K V+
Sbjct: 181 HHNEKYNETKFKNYIKTQILKPVL 204


>UniRef50_Q7QWJ4 Cluster: S-adenosylmethionine synthetase; n=1;
           Giardia lamblia ATCC 50803|Rep: S-adenosylmethionine
           synthetase - Giardia lamblia ATCC 50803
          Length = 436

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 41/84 (48%), Positives = 56/84 (66%), Gaps = 4/84 (4%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHKTQ---QQLLS-IVQKNFDLRPGKIVKELNLRAPIYQ 676
           Q+ YAI VAEP+SI V  YG+  K +   QQL+   +++ F L PGKI++E  L  PI+ 
Sbjct: 353 QIGYAIGVAEPVSIFVEMYGSELKPEYADQQLIERAIRRTFGLTPGKIIQEYALDTPIFF 412

Query: 677 RTSTYGHFGRAGFPWEIPKPLIVE 748
            TS YGHFGR+ FPWE P+ L ++
Sbjct: 413 NTSRYGHFGRSEFPWEQPRRLTLD 436



 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 34/66 (51%), Positives = 41/66 (62%)
 Frame = +3

Query: 279 TVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAAR 458
           T + INP   F+IGGP+SD GLTGRK+I D+Y             KD +KVDRS AY AR
Sbjct: 274 TKLLINPSDRFVIGGPKSDCGLTGRKVIADSYGSFGSHGGGAFSGKDASKVDRSGAYLAR 333

Query: 459 WVAKSL 476
            +A SL
Sbjct: 334 NIAMSL 339



 Score = 44.8 bits (101), Expect = 0.002
 Identities = 27/80 (33%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
 Frame = +1

Query: 10  MPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVF--AGGATVPQRVHTVVVSL 183
           MP T + A+ L  +++ +R+ G   + RPDSKTQVT +Y          P  + T+++S 
Sbjct: 139 MPATHLFANLLAMRLSRVRKTGVLPFLRPDSKTQVTIKYEEDPLTKELRPIFLDTLIIST 198

Query: 184 QHSEKITLETLRDEIREKVI 243
            H+E+I    LR  I + V+
Sbjct: 199 MHAEEIGNTALRTAIFKHVV 218


>UniRef50_Q7NB16 Cluster: S-adenosylmethionine synthetase; n=2;
           Mycoplasmataceae|Rep: S-adenosylmethionine synthetase -
           Mycoplasma gallisepticum
          Length = 395

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 36/65 (55%), Positives = 45/65 (69%)
 Frame = +3

Query: 291 INPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAK 470
           INP GLF+ GGP +D GLTGRK++VD++             KD+TKVDRS AY ARW+AK
Sbjct: 234 INPSGLFVSGGPTADTGLTGRKLLVDSFGIYAHHGGGAYSGKDYTKVDRSGAYYARWIAK 293

Query: 471 SLVKA 485
            +VKA
Sbjct: 294 HIVKA 298



 Score = 42.3 bits (95), Expect = 0.013
 Identities = 25/81 (30%), Positives = 43/81 (53%)
 Frame = +1

Query: 10  MPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSLQH 189
           MPL V++AH L +   EL  N  F  A+ D K QV+  Y+          + T+++S+QH
Sbjct: 144 MPLAVMMAHDLVRLAKELIDNKTFNHAKYDMKAQVSLNYLDNNQV----ELKTILMSIQH 199

Query: 190 SEKITLETLRDEIREKVIKEV 252
            E + L   +  +++ ++ EV
Sbjct: 200 EENVDLSVFKLFVKKFIMDEV 220



 Score = 40.3 bits (90), Expect = 0.051
 Identities = 22/67 (32%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
 Frame = +2

Query: 512 VAYAISVAEPLSITVFDYGTSHKTQQQLLS-IVQKNFDLRPGKIVKELNLRAPIYQRTST 688
           +++AI + +PL I V  + T H  +  L++ IV+K F+     I++ L L+   Y   + 
Sbjct: 308 ISWAIGLTKPLDIVVNCFNT-HTVELDLINQIVKKIFNHDLATIIELLKLKTTNYSGLAV 366

Query: 689 YGHFGRA 709
           YGHFG++
Sbjct: 367 YGHFGKS 373


>UniRef50_A7APP7 Cluster: S-adenosylmethionine synthetase, putative;
           n=1; Babesia bovis|Rep: S-adenosylmethionine synthetase,
           putative - Babesia bovis
          Length = 416

 Score = 81.4 bits (192), Expect = 2e-14
 Identities = 41/78 (52%), Positives = 49/78 (62%)
 Frame = +3

Query: 255 PAQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVD 434
           P+++LD+ TV   NP G ++ GGP  D+GLTGRKI+VDTY             KD TKVD
Sbjct: 229 PSKFLDKDTVYLFNPSGKWVHGGPACDSGLTGRKIVVDTYGGWGAHGGGCFSGKDATKVD 288

Query: 435 RSAAYAARWVAKSLVKAG 488
           RS AY  R VAKSLV  G
Sbjct: 289 RSGAYYCRLVAKSLVANG 306



 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 36/93 (38%), Positives = 58/93 (62%), Gaps = 1/93 (1%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEY-VFAGGATVPQRVHTVVVS 180
           E MPL+  LA +L +++ ++R+     + RPD KTQ+T EY V   G   P RVHTV++S
Sbjct: 144 ELMPLSHALATRLGKRLTKVRKTKVMPYLRPDGKTQITVEYRVEPNGHLEPVRVHTVLIS 203

Query: 181 LQHSEKITLETLRDEIREKVIKEVILHNILMRE 279
            QH   ++L+TLR+++ E V+K  +    L ++
Sbjct: 204 TQHDPDVSLDTLREDLMEHVVKPTVPSKFLDKD 236



 Score = 73.7 bits (173), Expect = 5e-12
 Identities = 37/76 (48%), Positives = 51/76 (67%), Gaps = 4/76 (5%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHK--TQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRT 682
           QVAY+I+VA PLS+ +  +GT  +     +L  IV +NFD R G I+K+L+L  PI+ +T
Sbjct: 314 QVAYSIAVANPLSLHINSFGTCAEGFDDNKLKEIVFRNFDFRVGCIIKQLDLTRPIFSKT 373

Query: 683 STYGHFGRAG--FPWE 724
           S YGHFGR G  + WE
Sbjct: 374 SCYGHFGRHGDEYTWE 389


>UniRef50_Q6KHY1 Cluster: S-adenosylmethionine synthetase; n=7;
           Mycoplasma|Rep: S-adenosylmethionine synthetase -
           Mycoplasma mobile
          Length = 386

 Score = 80.2 bits (189), Expect = 5e-14
 Identities = 42/73 (57%), Positives = 45/73 (61%)
 Frame = +3

Query: 267 LDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAA 446
           L+    I IN  G F IGGP  D GLTGRKIIVDTY             KD+TKVDRS A
Sbjct: 209 LNRNFEILINTAGDFTIGGPIGDTGLTGRKIIVDTYGGWARHGGGAFSGKDYTKVDRSGA 268

Query: 447 YAARWVAKSLVKA 485
           Y ARWVAK+LV A
Sbjct: 269 YFARWVAKNLVAA 281



 Score = 50.4 bits (115), Expect = 5e-05
 Identities = 25/67 (37%), Positives = 45/67 (67%), Gaps = 1/67 (1%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKN-FDLRPGKIVKELNLRAPIYQRTS 685
           Q A+AI    P++I +    T+ K + +L+  V KN F+   G+I+++L+L+ PIY++ +
Sbjct: 290 QFAFAIGKEMPIAINI--NVTNEKYKIELIEKVVKNLFNFNVGEIIEKLDLKKPIYEQVA 347

Query: 686 TYGHFGR 706
           ++GHFGR
Sbjct: 348 SFGHFGR 354



 Score = 45.2 bits (102), Expect = 0.002
 Identities = 29/82 (35%), Positives = 49/82 (59%), Gaps = 1/82 (1%)
 Frame = +1

Query: 1   EECMPLTVVLAHKLNQKIAELRR-NGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVV 177
           E+ +PL  V+AH++  KIAE +R N  F  A+ D K+QVT +Y        P+ V T++V
Sbjct: 124 EQFLPLNFVIAHEI-LKIAEKKRLNKTFQNAKSDMKSQVTMDY---SDPKNPKLV-TIIV 178

Query: 178 SLQHSEKITLETLRDEIREKVI 243
           ++QH + I  +     I++++I
Sbjct: 179 AIQHEKNIDKDEFEKFIKDEII 200


>UniRef50_Q2GDS4 Cluster: S-adenosylmethionine synthetase; n=1;
           Neorickettsia sennetsu str. Miyayama|Rep:
           S-adenosylmethionine synthetase - Neorickettsia sennetsu
           (strain Miyayama)
          Length = 382

 Score = 79.4 bits (187), Expect = 9e-14
 Identities = 38/68 (55%), Positives = 45/68 (66%)
 Frame = +3

Query: 285 IHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWV 464
           I INP G F IGGP+ D GLTGRKI+ DTY             KD TKVDRSAAY AR++
Sbjct: 217 IIINPAGAFTIGGPKGDCGLTGRKIVADTYGGVIPNGGGAFSGKDATKVDRSAAYLARYI 276

Query: 465 AKSLVKAG 488
           AK++V +G
Sbjct: 277 AKNIVFSG 284



 Score = 50.0 bits (114), Expect = 6e-05
 Identities = 25/73 (34%), Positives = 41/73 (56%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTST 688
           Q+ YAI +  PL++ +   G +   ++Q+ S++    D  P  I   L+L  PIY +TST
Sbjct: 292 QLCYAIGMDAPLNVQISLPGITACDEEQIFSLIVDKIDFSPLGISTLLHLDRPIYLKTST 351

Query: 689 YGHFGRAGFPWEI 727
            GHFG +  P ++
Sbjct: 352 IGHFGHSYNPTDM 364



 Score = 38.3 bits (85), Expect = 0.21
 Identities = 19/50 (38%), Positives = 30/50 (60%)
 Frame = +1

Query: 94  PDSKTQVTCEYVFAGGATVPQRVHTVVVSLQHSEKITLETLRDEIREKVI 243
           PD K+Q+T EY F+G    P  V  VV S+QH   ++   +R+ + EK++
Sbjct: 157 PDGKSQITIEYDFSGR---PVGVTNVVASVQHPAGMSTRDVRNTLLEKIV 203


>UniRef50_O09486 Cluster: S-adenosylmethionine synthetase; n=1;
           Amoeba proteus|Rep: S-adenosylmethionine synthetase -
           Amoeba proteus (Amoeba)
          Length = 426

 Score = 79.4 bits (187), Expect = 9e-14
 Identities = 40/80 (50%), Positives = 50/80 (62%), Gaps = 3/80 (3%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAP---IYQR 679
           QV+Y I   EPL+I V  YGT   +  +LL I+ KNFD RPG I++EL+L  P    Y  
Sbjct: 345 QVSYVIGKPEPLNIYVNTYGTGTHSDSELLEIINKNFDFRPGFIIEELDLLNPDRIKYVE 404

Query: 680 TSTYGHFGRAGFPWEIPKPL 739
           T+ +GHFGR  FPWE  K L
Sbjct: 405 TAYHGHFGRPEFPWEQEKTL 424



 Score = 66.9 bits (156), Expect = 5e-10
 Identities = 33/57 (57%), Positives = 40/57 (70%)
 Frame = +3

Query: 315 IGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAKSLVKA 485
           +GGP +DAG TGRKIIVDTY             KD +KVDRSAAY AR+VA++LV+A
Sbjct: 280 VGGPNADAGTTGRKIIVDTYGGHGAHGGGAFSGKDPSKVDRSAAYYARYVAQNLVRA 336



 Score = 49.2 bits (112), Expect = 1e-04
 Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
 Frame = +1

Query: 16  LTVVLAHKLNQKIA--ELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSLQH 189
           L V    K++Q  A  ELR   +FWW   D+K+QV  EY    GA  P      V+S+QH
Sbjct: 173 LAVAKGIKVSQVDATPELRDTIDFWWLHTDAKSQVIIEYEDDSGALKPITARVAVLSVQH 232

Query: 190 SEKITLETLRDEIREKV 240
           S+ +T +   D + + V
Sbjct: 233 SKFVTHDQYEDRLPQLV 249


>UniRef50_UPI00015BD1C2 Cluster: UPI00015BD1C2 related cluster; n=1;
           unknown|Rep: UPI00015BD1C2 UniRef100 entry - unknown
          Length = 372

 Score = 78.6 bits (185), Expect = 2e-13
 Identities = 38/78 (48%), Positives = 48/78 (61%)
 Frame = +3

Query: 255 PAQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVD 434
           P + L + T I INP G FIIGGP +D G+TGRKI+ D Y             KD TK D
Sbjct: 207 PNELLRKETKIKINPAGRFIIGGPVADTGMTGRKIVSDAYGDISFSGGSAFSGKDPTKTD 266

Query: 435 RSAAYAARWVAKSLVKAG 488
           R+A+Y AR++AK +V AG
Sbjct: 267 RAASYMARYIAKHIVAAG 284



 Score = 76.2 bits (179), Expect = 8e-13
 Identities = 33/72 (45%), Positives = 46/72 (63%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTST 688
           Q+AYA  V EP+   +  +GT  K    + S +++ F L P  I++ L+LR PIY+RTS 
Sbjct: 292 QIAYAFGVKEPIGFDIETFGTETKPIDLIKSRIREVFSLYPKDIIETLDLRKPIYKRTSC 351

Query: 689 YGHFGRAGFPWE 724
           YGHFG+ G PWE
Sbjct: 352 YGHFGKEGLPWE 363



 Score = 45.6 bits (103), Expect = 0.001
 Identities = 27/93 (29%), Positives = 49/93 (52%)
 Frame = +1

Query: 1   EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVS 180
           E  +P  +  AHK+++  ++ R+ G   + RPD KT V  +Y           + ++ + 
Sbjct: 126 ESFLPAPIYFAHKISKTTSDFRKKGIMPFLRPDGKTIVGIKYENQN----KFYIDSINMF 181

Query: 181 LQHSEKITLETLRDEIREKVIKEVILHNILMRE 279
           +QH   I+L  LR+ I E +IK+ I + +L +E
Sbjct: 182 VQHDPDISLNHLRELIFEDIIKKHIPNELLRKE 214


>UniRef50_Q6A7D8 Cluster: S-adenosylmethionine synthetase; n=11;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Propionibacterium acnes
          Length = 396

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 37/74 (50%), Positives = 49/74 (66%)
 Frame = +3

Query: 267 LDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAA 446
           +DE T I +NP G F+ GGP++D GLTGRK++V TY             KD +KVDRSAA
Sbjct: 220 IDEHTEILVNPSGRFVEGGPRADTGLTGRKLMVGTYGGLGSHGGGAFSGKDPSKVDRSAA 279

Query: 447 YAARWVAKSLVKAG 488
           Y AR +A+++V AG
Sbjct: 280 YMARLIARTIVDAG 293



 Score = 56.4 bits (130), Expect = 7e-07
 Identities = 33/92 (35%), Positives = 44/92 (47%), Gaps = 3/92 (3%)
 Frame = +2

Query: 458 MGRQVAR---QGGLVPVLHGQVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLR 628
           M R +AR     GL       ++YAI  A+P++  V   GT       L +  +  F LR
Sbjct: 281 MARLIARTIVDAGLAAECEVGISYAIGKADPVAFEVDTLGTGEYADHILTAAARDVFVLR 340

Query: 629 PGKIVKELNLRAPIYQRTSTYGHFGRAGFPWE 724
           P  I+  LNLR P Y+  + YGH GR    WE
Sbjct: 341 PAGIIDVLNLRTPRYRDLAVYGHMGRDWPRWE 372



 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 27/80 (33%), Positives = 41/80 (51%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSL 183
           E +PL +VLAH++ +++   +  G     + D K QV+  Y   G    P  V TVVVS+
Sbjct: 134 ERLPLPLVLAHRICERLDTAQVEGTICGIKSDGKAQVSVRYDDTG---APAAVETVVVSV 190

Query: 184 QHSEKITLETLRDEIREKVI 243
           QH     L  L  E+R  ++
Sbjct: 191 QHEAGKDLAVLEREVRSLIV 210


>UniRef50_Q6SZ22 Cluster: S-adenosylmethionine synthetase; n=4;
           Streptococcus|Rep: S-adenosylmethionine synthetase -
           Streptococcus pyogenes
          Length = 353

 Score = 77.0 bits (181), Expect = 5e-13
 Identities = 38/91 (41%), Positives = 56/91 (61%)
 Frame = +2

Query: 452 RPMGRQVARQGGLVPVLHGQVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRP 631
           R + + + R+G        Q+AYAI VAEP+S+ V  +GTS  T  QL  ++++ +DL P
Sbjct: 263 RKIAKDIVREG-YAKRCEVQLAYAIGVAEPVSVYVETFGTSRYTSTQLEGMIRERYDLTP 321

Query: 632 GKIVKELNLRAPIYQRTSTYGHFGRAGFPWE 724
             I+KEL+L    Y +TS +GHF +A  PWE
Sbjct: 322 QGIIKELHLLNVDYTKTSCFGHFTKAYLPWE 352



 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 33/66 (50%), Positives = 43/66 (65%)
 Frame = +3

Query: 291 INPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAK 470
           +NP G F++GG  +DAG+TGRKI+ DTY             KD +KVDRSAAY AR +AK
Sbjct: 208 VNPTGRFVLGGSFADAGVTGRKIVADTYGGFAHHGGGAFSGKDPSKVDRSAAYMARKIAK 267

Query: 471 SLVKAG 488
            +V+ G
Sbjct: 268 DIVREG 273


>UniRef50_A6QA94 Cluster: S-adenosylmethionine synthetase; n=20;
           Epsilonproteobacteria|Rep: S-adenosylmethionine
           synthetase - Sulfurovum sp. (strain NBC37-1)
          Length = 405

 Score = 76.6 bits (180), Expect = 6e-13
 Identities = 36/80 (45%), Positives = 51/80 (63%), Gaps = 1/80 (1%)
 Frame = +3

Query: 252 YPAQYLD-ERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTK 428
           + A + D ++TV +IN  G ++   P +D+GLTGRK++ DTY             KD++K
Sbjct: 222 FEAGHFDADKTVFYINNTGRYVTHSPIADSGLTGRKVVCDTYGGYAPIGGGAQSSKDYSK 281

Query: 429 VDRSAAYAARWVAKSLVKAG 488
           VDRSA YAARW+AK +V AG
Sbjct: 282 VDRSALYAARWLAKHIVAAG 301


>UniRef50_A6BGC6 Cluster: S-adenosylmethionine synthetase; n=1;
           Dorea longicatena DSM 13814|Rep: S-adenosylmethionine
           synthetase - Dorea longicatena DSM 13814
          Length = 387

 Score = 76.6 bits (180), Expect = 6e-13
 Identities = 38/72 (52%), Positives = 47/72 (65%)
 Frame = +3

Query: 270 DERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAY 449
           DE T I INP G F+ GG  +D GLTGRK++VDTY             KD +KVDRSAAY
Sbjct: 222 DEDTKILINPSGKFVCGGFDADTGLTGRKLMVDTYGSMVPHGGGAFSGKDCSKVDRSAAY 281

Query: 450 AARWVAKSLVKA 485
            AR++AK++V A
Sbjct: 282 MARYIAKNIVAA 293



 Score = 60.1 bits (139), Expect = 6e-08
 Identities = 29/72 (40%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
 Frame = +2

Query: 512 VAYAISVAEPLSITVFDYGTSHKTQQQLLSI-VQKNFDLRPGKIVKELNLRAPIYQRTST 688
           +AYAI VAEP+ I V  + T        L+  +   F + P +I++ L L  PI+++T+ 
Sbjct: 303 LAYAIGVAEPVMIEVDTFDTGKVCADDCLAAAIPLVFGVTPVQIMESLRLNRPIFRQTAV 362

Query: 689 YGHFGRAGFPWE 724
           +GHFGR  FPWE
Sbjct: 363 FGHFGRKEFPWE 374



 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 33/84 (39%), Positives = 50/84 (59%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSL 183
           + MP+  VLAH++ ++++  RR+G       D K QVT EY    G   P R+ +VVVS 
Sbjct: 137 QLMPMPTVLAHRITRELSACRRSGYIKDIFSDGKAQVTVEY--EDGK--PVRLESVVVSC 192

Query: 184 QHSEKITLETLRDEIREKVIKEVI 255
           QH  + +L+ L  EIREKV++  +
Sbjct: 193 QHGAEKSLKKLDAEIREKVLRSAL 216


>UniRef50_A5BU08 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 158

 Score = 76.6 bits (180), Expect = 6e-13
 Identities = 34/68 (50%), Positives = 44/68 (64%)
 Frame = +3

Query: 255 PAQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVD 434
           P +YLD++T+ H+NP G F+I GP+ D GLTGRKII+DTY             KD TK+D
Sbjct: 87  PKKYLDKKTIFHLNPSGRFVIDGPRGDVGLTGRKIIIDTYKGWGGHDGGVCSGKDPTKMD 146

Query: 435 RSAAYAAR 458
           R+ A  AR
Sbjct: 147 RNGACMAR 154


>UniRef50_P78003 Cluster: S-adenosylmethionine synthetase; n=4;
           Mycoplasma|Rep: S-adenosylmethionine synthetase -
           Mycoplasma pneumoniae
          Length = 383

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 37/75 (49%), Positives = 48/75 (64%), Gaps = 1/75 (1%)
 Frame = +3

Query: 267 LDERTVIH-INPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSA 443
           L++  + H +NP G F++GGP +D GLTGRKIIVDTY             KD TKVDR+ 
Sbjct: 212 LNDPKIKHLVNPGGSFVVGGPMADTGLTGRKIIVDTYGPYANHGGGSFSGKDPTKVDRTG 271

Query: 444 AYAARWVAKSLVKAG 488
           AY AR++AK +V  G
Sbjct: 272 AYFARFIAKHIVSLG 286



 Score = 40.7 bits (91), Expect = 0.039
 Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
 Frame = +2

Query: 512 VAYAISVAEPLSITVFDYGTSHKTQQQLLS-IVQKNFDLRPGKIVKELNLRAPI-YQRTS 685
           +++  S   P SI V  +  + +  +QL++ ++ + F+    KI+ +L L   + Y R +
Sbjct: 295 ISWVFSQPLPQSIQVKCFNINKEFSEQLINQVISQYFNWSVAKIIAKLKLLDQVEYFRYA 354

Query: 686 TYGHFGRAGFPWE 724
            YGHFG    PWE
Sbjct: 355 VYGHFGHQTAPWE 367


>UniRef50_Q5EK82 Cluster: S-adenosyl methionine synthetase 2; n=6;
           Spermatophyta|Rep: S-adenosyl methionine synthetase 2 -
           Pinus taeda (Loblolly pine)
          Length = 115

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 39/82 (47%), Positives = 52/82 (63%), Gaps = 5/82 (6%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRA---PIYQR 679
           QV+YAI V EPLSI V  YGT     +++L I++++FD RPG I   L+L+      +Q+
Sbjct: 27  QVSYAIGVPEPLSIFVDSYGTGSIPDKEILEIIKEHFDFRPGMITINLDLKRGGNGRFQK 86

Query: 680 TSTYGHFGR--AGFPWEIPKPL 739
           T+ YGHFGR    F WE  KPL
Sbjct: 87  TAAYGHFGRDDPDFTWETVKPL 108


>UniRef50_Q1VNA9 Cluster: S-adenosylmethionine synthetase; n=1;
           Psychroflexus torquis ATCC 700755|Rep:
           S-adenosylmethionine synthetase - Psychroflexus torquis
           ATCC 700755
          Length = 344

 Score = 72.9 bits (171), Expect = 8e-12
 Identities = 35/74 (47%), Positives = 47/74 (63%)
 Frame = +3

Query: 258 AQYLDERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDR 437
           A ++++   + +NP G F+ GGP  D GLTGRKI+VD Y             KD +KVDR
Sbjct: 185 ATHVNQNFQLDLNPSGSFVKGGPAGDTGLTGRKIVVDAYGPSVPVGGGAFSGKDPSKVDR 244

Query: 438 SAAYAARWVAKSLV 479
           SAAYAAR +AK++V
Sbjct: 245 SAAYAARHLAKNIV 258



 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 26/72 (36%), Positives = 41/72 (56%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTST 688
           +V+YAI  AEP  +TV  + TS+  +  +   V K FD++PG I++ L+L    Y+  + 
Sbjct: 269 RVSYAIGKAEPYELTVNTFDTSNVKENVINDFVNK-FDMKPGAIIERLDLINVNYRIDTL 327

Query: 689 YGHFGRAGFPWE 724
           + HFG     WE
Sbjct: 328 FSHFGHDDRNWE 339


>UniRef50_Q5FGR4 Cluster: S-adenosylmethionine synthetase; n=13;
           Rickettsiales|Rep: S-adenosylmethionine synthetase -
           Ehrlichia ruminantium (strain Gardel)
          Length = 401

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 34/65 (52%), Positives = 43/65 (66%)
 Frame = +3

Query: 291 INPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAK 470
           +N  G F+IGGP  D GLTGRKI++DTY             KD +KVDRSAAY AR++AK
Sbjct: 229 VNTTGRFVIGGPVGDCGLTGRKIMIDTYGGHVPHGGGAFSGKDPSKVDRSAAYMARYLAK 288

Query: 471 SLVKA 485
           ++V A
Sbjct: 289 NIVSA 293



 Score = 59.7 bits (138), Expect = 8e-08
 Identities = 31/77 (40%), Positives = 41/77 (53%), Gaps = 5/77 (6%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTST 688
           Q++YAI ++ P S  V  +GT      ++   +  N DL P  I K L L  PIY+ TS+
Sbjct: 302 QISYAIGISSPTSFYVNTFGTGIIDDNEIQKFIMDNIDLSPYGICKHLLLFNPIYKITSS 361

Query: 689 YGHFGR-----AGFPWE 724
           YGHFGR       F WE
Sbjct: 362 YGHFGRIPSLNGSFSWE 378



 Score = 44.0 bits (99), Expect = 0.004
 Identities = 25/84 (29%), Positives = 44/84 (52%)
 Frame = +1

Query: 1   EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVS 180
           E  MP ++  +H + + I +  ++ E     PD+KTQ+T  Y       +P +V  V++S
Sbjct: 137 ETLMPASIFYSHLILRNIMDAVKSCEIPKLGPDAKTQITLVY----ENNIPVKVSNVILS 192

Query: 181 LQHSEKITLETLRDEIREKVIKEV 252
           +QH E IT   +R+ +   V K +
Sbjct: 193 IQHPEYITQNQIREIVYPYVSKSL 216


>UniRef50_UPI000039A2E5 Cluster: COG0192: S-adenosylmethionine
           synthetase; n=1; Rickettsia rickettsii|Rep: COG0192:
           S-adenosylmethionine synthetase - Rickettsia rickettsii
          Length = 85

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 29/61 (47%), Positives = 44/61 (72%)
 Frame = +2

Query: 524 ISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTSTYGHFG 703
           I VA P+S+     GTS  + +Q+  ++ ++FD+RPG+I+K L LR P YQ+T++YGHFG
Sbjct: 8   IGVAAPVSVYAETCGTSTLSNEQITKLITQHFDMRPGRIIKHLKLRTPCYQQTASYGHFG 67

Query: 704 R 706
           R
Sbjct: 68  R 68


>UniRef50_A7Q4X0 Cluster: Chromosome undetermined scaffold_51, whole
           genome shotgun sequence; n=2; Vitis vinifera|Rep:
           Chromosome undetermined scaffold_51, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 306

 Score = 70.1 bits (164), Expect = 6e-11
 Identities = 32/67 (47%), Positives = 42/67 (62%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSL 183
           E MPL+  LA KL  ++ E+++NG   W +PD KTQVT EY    GA VP  VH V++  
Sbjct: 27  ELMPLSHALATKLGTRLTEVKKNGTCSWLKPDGKTQVTIEYHNENGAMVPFHVHIVLIPT 86

Query: 184 QHSEKIT 204
           QH E +T
Sbjct: 87  QHDETVT 93


>UniRef50_A5AMB5 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 237

 Score = 68.5 bits (160), Expect = 2e-10
 Identities = 33/67 (49%), Positives = 44/67 (65%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVSL 183
           E MPL  VLA KL  +++E+ +NG + W RP+ KTQV  +Y   G A VP R+HTV+ S 
Sbjct: 165 EFMPLNHVLATKLGARLSEVCKNGTYPWLRPNDKTQVIVKYHNDGDAMVPIRMHTVLTST 224

Query: 184 QHSEKIT 204
           QH E +T
Sbjct: 225 QHDEIVT 231


>UniRef50_A4QEH8 Cluster: Putative uncharacterized protein; n=1;
           Corynebacterium glutamicum R|Rep: Putative
           uncharacterized protein - Corynebacterium glutamicum
           (strain R)
          Length = 257

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 34/85 (40%), Positives = 49/85 (57%)
 Frame = +1

Query: 1   EECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVHTVVVS 180
           EE MPL + LAH+L++++ ++R+ G     RPD KTQVT  Y        P  + TVV+S
Sbjct: 146 EEYMPLPIALAHRLSRRLTQVRKEGIVPHLRPDGKTQVTFAY---DAQDRPSHLDTVVIS 202

Query: 181 LQHSEKITLETLRDEIREKVIKEVI 255
            QH  ++    L  ++RE VI  VI
Sbjct: 203 TQHDPEVDRAWLETQLREHVIDWVI 227


>UniRef50_Q027Y1 Cluster: Methionine adenosyltransferase; n=1;
           Solibacter usitatus Ellin6076|Rep: Methionine
           adenosyltransferase - Solibacter usitatus (strain
           Ellin6076)
          Length = 364

 Score = 61.3 bits (142), Expect = 3e-08
 Identities = 28/67 (41%), Positives = 40/67 (59%)
 Frame = +3

Query: 288 HINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVA 467
           H+N  G F +GGP+ D GL+G+K++VD Y             KDF K DR+ A  AR +A
Sbjct: 221 HVNGAGNFEVGGPEGDNGLSGKKLVVDGYGPRVPIGGGALSGKDFFKADRAGAILARRLA 280

Query: 468 KSLVKAG 488
           K++V +G
Sbjct: 281 KAVVMSG 287


>UniRef50_Q60BL6 Cluster: S-adenosylmethionine synthetase; n=6;
           Bacteria|Rep: S-adenosylmethionine synthetase -
           Methylococcus capsulatus
          Length = 397

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 31/73 (42%), Positives = 40/73 (54%)
 Frame = +3

Query: 270 DERTVIHINPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAY 449
           DE T I +NP G+    GP + +G+TGRK   DTY             K   ++DR AAY
Sbjct: 226 DEHTEIFVNPRGMLHRSGPAAHSGMTGRKSASDTYGGYARHAGSALSGKGPLRIDRVAAY 285

Query: 450 AARWVAKSLVKAG 488
           AAR  AK++V AG
Sbjct: 286 AARHAAKNVVAAG 298



 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 9/89 (10%)
 Frame = +2

Query: 485 GLVPVLHGQVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNL-- 658
           GL      Q++Y I  A P+S+ V  +GT    +  +   ++K+FD R G IV++ NL  
Sbjct: 298 GLAEECEVQLSYTIGQARPVSVQVSTFGTGLVGEDVIKQRLEKHFDFRLGAIVRDFNLRR 357

Query: 659 -----RAPIYQRTSTYGHFGRA--GFPWE 724
                R   Y+R   YGHFG +    PWE
Sbjct: 358 LPAEYRGSFYRRLPAYGHFGASFTALPWE 386



 Score = 42.7 bits (96), Expect = 0.010
 Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVPQRVH--TVVV 177
           E +PL +VLA +L  ++   RR GE  +  PD  TQV  E  F  G   P R+H  T++ 
Sbjct: 137 ELLPLPIVLARRLAHQLTGARRRGEVPYLSPDCTTQVGVE--FEQGR--PARIHSITLIA 192

Query: 178 SLQHSEKITLETLRDEIREKVIKEVILHNILM 273
                  + LE LR ++ + VI        LM
Sbjct: 193 GTHGVPDLGLEELRRDLGQWVIAPAFEGEALM 224


>UniRef50_Q0GGP1 Cluster: S-adenosylmethionine synthetase; n=2;
           Alexandrium minutum|Rep: S-adenosylmethionine synthetase
           - Alexandrium minutum
          Length = 112

 Score = 56.0 bits (129), Expect = 1e-06
 Identities = 28/63 (44%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
 Frame = +2

Query: 524 ISVAEPLSITVFDYGTSHK--TQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTSTYGH 697
           I VA+PLS+ V  YGT     + + + ++++  FD RPG I   L LR P YQ T+ Y H
Sbjct: 5   IGVAKPLSLFVETYGTEQGALSAEDITNVIKIAFDCRPGAIAMSLALREPKYQETAAYCH 64

Query: 698 FGR 706
           FGR
Sbjct: 65  FGR 67


>UniRef50_Q0JN66 Cluster: Os01g0323600 protein; n=1; Oryza sativa
           (japonica cultivar-group)|Rep: Os01g0323600 protein -
           Oryza sativa subsp. japonica (Rice)
          Length = 212

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 29/62 (46%), Positives = 34/62 (54%)
 Frame = +2

Query: 320 RTSVRRGPDGTQNHRGHVWRVGGARRGRFLWQGLHQGRPLRSIRRPMGRQVARQGGLVPV 499
           R   RR P   Q+H  H+ R+G ARR R L QG  QGRP R + R  GRQ  R+    P 
Sbjct: 67  RAPRRRRPHRPQDHHRHLRRMGRARRRRLLRQGPDQGRPERRLHRQAGRQEHRRQRPRPP 126

Query: 500 LH 505
           LH
Sbjct: 127 LH 128


>UniRef50_A7NSM8 Cluster: Chromosome chr18 scaffold_1, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr18 scaffold_1, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 509

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 24/48 (50%), Positives = 31/48 (64%)
 Frame = +1

Query: 10  MPLTVVLAHKLNQKIAELRRNGEFWWARPDSKTQVTCEYVFAGGATVP 153
           MPL+ VL+ KL+ ++ E+R+N    W RPD KTQVT EY    GA  P
Sbjct: 368 MPLSHVLSTKLSARLTEVRKNETCSWLRPDGKTQVTVEYHDENGAMAP 415


>UniRef50_Q9S992 Cluster: MET adenosyltransferase homolog; n=3; core
           eudicotyledons|Rep: MET adenosyltransferase homolog -
           Brassica napus (Rape)
          Length = 68

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/56 (41%), Positives = 36/56 (64%), Gaps = 5/56 (8%)
 Frame = +2

Query: 587 QQLLSIVQKNFDLRPGKIVKELNLRA---PIYQRTSTYGHFGR--AGFPWEIPKPL 739
           +++L IV+++FD RPG +   L+L+      + +T+ YGHFGR    F WE+ KPL
Sbjct: 6   KEILKIVKESFDFRPGMMTINLDLKRGGNGRFLKTAAYGHFGRDDPDFTWEVVKPL 61


>UniRef50_Q2LSR0 Cluster: S-adenosylmethionine synthetase; n=1;
           Syntrophus aciditrophicus SB|Rep: S-adenosylmethionine
           synthetase - Syntrophus aciditrophicus (strain SB)
          Length = 392

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 29/80 (36%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
 Frame = +3

Query: 261 QYLDERTVIHINPCGLF--IIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFT--K 428
           +++DE+T    NP G +  +     +D+G+TGRK++V  Y              + T  K
Sbjct: 221 EWVDEQTDFLFNPTGEWQSVNSCSAADSGVTGRKLVVQLYGGYPGAQLGGGSIVNKTPEK 280

Query: 429 VDRSAAYAARWVAKSLVKAG 488
           VD SAA  AR+VAK++V AG
Sbjct: 281 VDCSAALGARYVAKNIVAAG 300



 Score = 42.7 bits (96), Expect = 0.010
 Identities = 19/50 (38%), Positives = 33/50 (66%)
 Frame = +2

Query: 509 QVAYAISVAEPLSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNL 658
           Q++YAI +A P+SI V  +GT   +  ++ +IV++ FDL P  +++  NL
Sbjct: 308 QLSYAIGIARPISIYVHTFGTGVISDNKIGTIVREYFDLSPRGMIERFNL 357


>UniRef50_Q42242 Cluster: S-adenosyl methionine synthase; n=5;
           Eukaryota|Rep: S-adenosyl methionine synthase -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 56

 Score = 44.0 bits (99), Expect = 0.004
 Identities = 23/49 (46%), Positives = 31/49 (63%), Gaps = 5/49 (10%)
 Frame = +2

Query: 608 QKNFDLRPGKIVKELNLRAP---IYQRTSTYGHFGR--AGFPWEIPKPL 739
           +++FD RPG I   L+L+      + +TS YGHFGR  A F WE+ KPL
Sbjct: 1   KESFDFRPGMISINLDLKRGGNGRFLKTSAYGHFGRDDADFTWEVVKPL 49


>UniRef50_A6PKG8 Cluster: Methionine adenosyltransferase precursor;
           n=1; Victivallis vadensis ATCC BAA-548|Rep: Methionine
           adenosyltransferase precursor - Victivallis vadensis
           ATCC BAA-548
          Length = 338

 Score = 42.7 bits (96), Expect = 0.010
 Identities = 25/64 (39%), Positives = 29/64 (45%)
 Frame = +3

Query: 291 INPCGLFIIGGPQSDAGLTGRKIIVDTYXXXXXXXXXXXXXKDFTKVDRSAAYAARWVAK 470
           +N  G F+  GP  D G TGRK+ VD Y             KD TK D S    AR  A 
Sbjct: 209 VNGTGRFVKHGPIGDCGTTGRKLAVDFYGGNCVIGGGSPWTKDGTKADLSLNLLARARAV 268

Query: 471 SLVK 482
           S +K
Sbjct: 269 SYIK 272


>UniRef50_Q09A96 Cluster: Putative uncharacterized protein; n=1;
           Stigmatella aurantiaca DW4/3-1|Rep: Putative
           uncharacterized protein - Stigmatella aurantiaca DW4/3-1
          Length = 596

 Score = 38.3 bits (85), Expect = 0.21
 Identities = 30/85 (35%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
 Frame = -2

Query: 506 HAAPA-QARLDERLGDPSGGVCCGAVDLGEVLARESXXXXXXXXXXXVHDDFASRQARV* 330
           H APA Q R    LGD +  V  GAV LG VLARE            V DD  +R ARV 
Sbjct: 288 HLAPAGQTRGHHVLGDVAPHVRRGAVHLGRVLAREGAAAVTAHAAVGVDDDLPARHARVA 347

Query: 329 LRSSNYKESTWINVNYSSLIKILCR 255
             +++++ +  ++     L+  L R
Sbjct: 348 HGATHHEAAGGVDEELGLLVDELGR 372


>UniRef50_A2Y188 Cluster: Putative uncharacterized protein; n=1;
           Oryza sativa (indica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. indica
           (Rice)
          Length = 184

 Score = 36.3 bits (80), Expect = 0.84
 Identities = 20/47 (42%), Positives = 24/47 (51%)
 Frame = +2

Query: 347 GTQNHRGHVWRVGGARRGRFLWQGLHQGRPLRSIRRPMGRQVARQGG 487
           G Q  R  VW+         LW+G   GR  RS RRPMG++  R GG
Sbjct: 73  GNQRLRARVWK--RITVAALLWKGGVVGRGRRSGRRPMGKRKVRSGG 117


>UniRef50_Q6MA58 Cluster: Putative uncharacterized protein; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep:
           Putative uncharacterized protein - Protochlamydia
           amoebophila (strain UWE25)
          Length = 86

 Score = 35.5 bits (78), Expect = 1.5
 Identities = 17/48 (35%), Positives = 29/48 (60%)
 Frame = +2

Query: 542 LSITVFDYGTSHKTQQQLLSIVQKNFDLRPGKIVKELNLRAPIYQRTS 685
           LS  V  +GT   ++ +L  I+   FDL    +++ LNL+ P+Y++TS
Sbjct: 34  LSQKVDTFGTGTVSEAELSRIIPLIFDLTTKGVIQMLNLKRPVYRQTS 81


>UniRef50_Q8MU02 Cluster: Putative S-adenosylmethionine synthetase;
           n=1; Heterodera glycines|Rep: Putative
           S-adenosylmethionine synthetase - Heterodera glycines
           (Soybean cyst nematode worm)
          Length = 211

 Score = 35.1 bits (77), Expect = 1.9
 Identities = 15/23 (65%), Positives = 19/23 (82%)
 Frame = +1

Query: 4   ECMPLTVVLAHKLNQKIAELRRN 72
           E MPLT+VL+HKLN K  +LRR+
Sbjct: 185 EAMPLTLVLSHKLNAKYHQLRRS 207


>UniRef50_A0U6S4 Cluster: Putative uncharacterized protein
           precursor; n=5; Burkholderia|Rep: Putative
           uncharacterized protein precursor - Burkholderia
           cenocepacia MC0-3
          Length = 957

 Score = 34.7 bits (76), Expect = 2.6
 Identities = 20/42 (47%), Positives = 22/42 (52%)
 Frame = +2

Query: 362 RGHVWRVGGARRGRFLWQGLHQGRPLRSIRRPMGRQVARQGG 487
           RGH  RVG  RRGR   +G    R  R  RR +GR V R  G
Sbjct: 325 RGHALRVGRGRRGRLRQRGQQFARG-RGDRRALGRLVGRDEG 365


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 788,644,851
Number of Sequences: 1657284
Number of extensions: 16030010
Number of successful extensions: 47105
Number of sequences better than 10.0: 46
Number of HSP's better than 10.0 without gapping: 45006
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 47072
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 64204279620
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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