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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= pg--0226.Seq
         (544 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

X86446-1|CAA60167.1|  900|Homo sapiens 55.11 protein protein.         108   1e-23
U18247-1|AAA57339.1|  591|Homo sapiens p67 protein.                   108   1e-23
D78151-1|BAA11226.1|  908|Homo sapiens human 26S proteasome subu...   108   1e-23
BC002997-1|AAH02997.1|  908|Homo sapiens proteasome (prosome, ma...   108   1e-23
BC002368-1|AAH02368.1|  908|Homo sapiens proteasome (prosome, ma...   108   1e-23
AB209843-1|BAD93080.1|  913|Homo sapiens proteasome 26S non-ATPa...   108   1e-23
BT009736-1|AAP88738.1|  908|Homo sapiens proteasome (prosome, ma...   105   1e-22
BC007897-1|AAH07897.1|  908|Homo sapiens proteasome (prosome, ma...   105   1e-22
U12596-1|AAA87705.1|  853|Homo sapiens tumor necrosis factor typ...   103   5e-22
AK000917-1|BAA91423.1|  441|Homo sapiens protein ( Homo sapiens ...    33   0.65 
BC041792-1|AAH41792.1|  562|Homo sapiens AT rich interactive dom...    33   0.85 
AF116846-1|AAD09133.1|  560|Homo sapiens bright and dead ringer ...    33   0.85 
AB208830-1|BAD92067.1|  476|Homo sapiens AT rich interactive dom...    33   0.85 
BC029864-1|AAH29864.1|  340|Homo sapiens hyaluronan and proteogl...    32   1.5  
AL365181-11|CAI13055.1|  340|Homo sapiens hyaluronan and proteog...    32   1.5  
AL365181-10|CAI13054.1|  185|Homo sapiens hyaluronan and proteog...    32   1.5  
AB049061-1|BAB17669.1|  340|Homo sapiens brain link protein-1 pr...    32   1.5  
AB049054-1|BAB17662.1|  340|Homo sapiens brain link protein-1 pr...    32   1.5  
BC039867-1|AAH39867.1|  446|Homo sapiens WD repeat domain, phosp...    31   3.4  
AY691424-1|AAV80760.1|  447|Homo sapiens WIPI-1 alpha protein.         31   3.4  
AL136089-7|CAI20013.1|  448|Homo sapiens molybdenum cofactor syn...    29   8.0  

>X86446-1|CAA60167.1|  900|Homo sapiens 55.11 protein protein.
          Length = 900

 Score =  108 bits (259), Expect = 1e-23
 Identities = 47/88 (53%), Positives = 65/88 (73%)
 Frame = +3

Query: 249 PALSVIEVLNIYSHDSDNDVAYNSIFAMGLVGAGTNNXXXXXXXXXXXXYHGKSPVHLFM 428
           P L++++ L+ +SHD+D +V+YNSIFAMG+VG+GTNN            YH K P +LFM
Sbjct: 693 PRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFM 752

Query: 429 VLLAQGLCHAGKGTVTLCPAHANRRLLT 512
           V LAQGL H GKGT+TLCP H++R+L++
Sbjct: 753 VRLAQGLTHLGKGTLTLCPYHSDRQLMS 780



 Score = 75.4 bits (177), Expect = 1e-13
 Identities = 36/53 (67%), Positives = 41/53 (77%)
 Frame = +1

Query: 94  QAVATLGVAVIALAAETGAEMCTRIFGQLGRYGEPVVRRAVPLAIALCSVSNP 252
           Q VA LG+A+IA+  E GAEM  R FG L RYGEP +RRAVPLA+AL SVSNP
Sbjct: 641 QGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNP 693


>U18247-1|AAA57339.1|  591|Homo sapiens p67 protein.
          Length = 591

 Score =  108 bits (259), Expect = 1e-23
 Identities = 47/88 (53%), Positives = 65/88 (73%)
 Frame = +3

Query: 249 PALSVIEVLNIYSHDSDNDVAYNSIFAMGLVGAGTNNXXXXXXXXXXXXYHGKSPVHLFM 428
           P L++++ L+ +SHD+D +V+YNSIFAMG+VG+GTNN            YH K P +LFM
Sbjct: 384 PRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFM 443

Query: 429 VLLAQGLCHAGKGTVTLCPAHANRRLLT 512
           V LAQGL H GKGT+TLCP H++R+L++
Sbjct: 444 VRLAQGLTHLGKGTLTLCPYHSDRQLMS 471



 Score = 43.6 bits (98), Expect = 5e-04
 Identities = 19/23 (82%), Positives = 21/23 (91%)
 Frame = +1

Query: 184 RYGEPVVRRAVPLAIALCSVSNP 252
           RYGEP +RRAVPLA+AL SVSNP
Sbjct: 362 RYGEPTLRRAVPLALALISVSNP 384


>D78151-1|BAA11226.1|  908|Homo sapiens human 26S proteasome subunit
           p97 protein.
          Length = 908

 Score =  108 bits (259), Expect = 1e-23
 Identities = 47/88 (53%), Positives = 65/88 (73%)
 Frame = +3

Query: 249 PALSVIEVLNIYSHDSDNDVAYNSIFAMGLVGAGTNNXXXXXXXXXXXXYHGKSPVHLFM 428
           P L++++ L+ +SHD+D +V+YNSIFAMG+VG+GTNN            YH K P +LFM
Sbjct: 702 PRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFM 761

Query: 429 VLLAQGLCHAGKGTVTLCPAHANRRLLT 512
           V LAQGL H GKGT+TLCP H++R+L++
Sbjct: 762 VRLAQGLTHLGKGTLTLCPYHSDRQLMS 789



 Score = 75.4 bits (177), Expect = 1e-13
 Identities = 36/53 (67%), Positives = 41/53 (77%)
 Frame = +1

Query: 94  QAVATLGVAVIALAAETGAEMCTRIFGQLGRYGEPVVRRAVPLAIALCSVSNP 252
           Q VA LG+A+IA+  E GAEM  R FG L RYGEP +RRAVPLA+AL SVSNP
Sbjct: 650 QGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNP 702


>BC002997-1|AAH02997.1|  908|Homo sapiens proteasome (prosome,
           macropain) 26S subunit, non-ATPase, 2 protein.
          Length = 908

 Score =  108 bits (259), Expect = 1e-23
 Identities = 47/88 (53%), Positives = 65/88 (73%)
 Frame = +3

Query: 249 PALSVIEVLNIYSHDSDNDVAYNSIFAMGLVGAGTNNXXXXXXXXXXXXYHGKSPVHLFM 428
           P L++++ L+ +SHD+D +V+YNSIFAMG+VG+GTNN            YH K P +LFM
Sbjct: 702 PRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFM 761

Query: 429 VLLAQGLCHAGKGTVTLCPAHANRRLLT 512
           V LAQGL H GKGT+TLCP H++R+L++
Sbjct: 762 VRLAQGLTHLGKGTLTLCPYHSDRQLMS 789



 Score = 75.4 bits (177), Expect = 1e-13
 Identities = 36/53 (67%), Positives = 41/53 (77%)
 Frame = +1

Query: 94  QAVATLGVAVIALAAETGAEMCTRIFGQLGRYGEPVVRRAVPLAIALCSVSNP 252
           Q VA LG+A+IA+  E GAEM  R FG L RYGEP +RRAVPLA+AL SVSNP
Sbjct: 650 QGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNP 702


>BC002368-1|AAH02368.1|  908|Homo sapiens proteasome (prosome,
           macropain) 26S subunit, non-ATPase, 2 protein.
          Length = 908

 Score =  108 bits (259), Expect = 1e-23
 Identities = 47/88 (53%), Positives = 65/88 (73%)
 Frame = +3

Query: 249 PALSVIEVLNIYSHDSDNDVAYNSIFAMGLVGAGTNNXXXXXXXXXXXXYHGKSPVHLFM 428
           P L++++ L+ +SHD+D +V+YNSIFAMG+VG+GTNN            YH K P +LFM
Sbjct: 702 PRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFM 761

Query: 429 VLLAQGLCHAGKGTVTLCPAHANRRLLT 512
           V LAQGL H GKGT+TLCP H++R+L++
Sbjct: 762 VRLAQGLTHLGKGTLTLCPYHSDRQLMS 789



 Score = 75.4 bits (177), Expect = 1e-13
 Identities = 36/53 (67%), Positives = 41/53 (77%)
 Frame = +1

Query: 94  QAVATLGVAVIALAAETGAEMCTRIFGQLGRYGEPVVRRAVPLAIALCSVSNP 252
           Q VA LG+A+IA+  E GAEM  R FG L RYGEP +RRAVPLA+AL SVSNP
Sbjct: 650 QGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNP 702


>AB209843-1|BAD93080.1|  913|Homo sapiens proteasome 26S non-ATPase
           subunit 2 variant protein.
          Length = 913

 Score =  108 bits (259), Expect = 1e-23
 Identities = 47/88 (53%), Positives = 65/88 (73%)
 Frame = +3

Query: 249 PALSVIEVLNIYSHDSDNDVAYNSIFAMGLVGAGTNNXXXXXXXXXXXXYHGKSPVHLFM 428
           P L++++ L+ +SHD+D +V+YNSIFAMG+VG+GTNN            YH K P +LFM
Sbjct: 707 PRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFM 766

Query: 429 VLLAQGLCHAGKGTVTLCPAHANRRLLT 512
           V LAQGL H GKGT+TLCP H++R+L++
Sbjct: 767 VRLAQGLTHLGKGTLTLCPYHSDRQLMS 794



 Score = 75.4 bits (177), Expect = 1e-13
 Identities = 36/53 (67%), Positives = 41/53 (77%)
 Frame = +1

Query: 94  QAVATLGVAVIALAAETGAEMCTRIFGQLGRYGEPVVRRAVPLAIALCSVSNP 252
           Q VA LG+A+IA+  E GAEM  R FG L RYGEP +RRAVPLA+AL SVSNP
Sbjct: 655 QGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNP 707


>BT009736-1|AAP88738.1|  908|Homo sapiens proteasome (prosome,
           macropain) 26S subunit, non-ATPase, 2 protein.
          Length = 908

 Score =  105 bits (251), Expect = 1e-22
 Identities = 46/88 (52%), Positives = 64/88 (72%)
 Frame = +3

Query: 249 PALSVIEVLNIYSHDSDNDVAYNSIFAMGLVGAGTNNXXXXXXXXXXXXYHGKSPVHLFM 428
           P L++++ L+ +SHD+D +V+Y SIFAMG+VG+GTNN            YH K P +LFM
Sbjct: 702 PRLNILDTLSKFSHDADPEVSYYSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFM 761

Query: 429 VLLAQGLCHAGKGTVTLCPAHANRRLLT 512
           V LAQGL H GKGT+TLCP H++R+L++
Sbjct: 762 VRLAQGLTHLGKGTLTLCPYHSDRQLMS 789



 Score = 75.4 bits (177), Expect = 1e-13
 Identities = 36/53 (67%), Positives = 41/53 (77%)
 Frame = +1

Query: 94  QAVATLGVAVIALAAETGAEMCTRIFGQLGRYGEPVVRRAVPLAIALCSVSNP 252
           Q VA LG+A+IA+  E GAEM  R FG L RYGEP +RRAVPLA+AL SVSNP
Sbjct: 650 QGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNP 702


>BC007897-1|AAH07897.1|  908|Homo sapiens proteasome (prosome,
           macropain) 26S subunit, non-ATPase, 2 protein.
          Length = 908

 Score =  105 bits (251), Expect = 1e-22
 Identities = 46/88 (52%), Positives = 64/88 (72%)
 Frame = +3

Query: 249 PALSVIEVLNIYSHDSDNDVAYNSIFAMGLVGAGTNNXXXXXXXXXXXXYHGKSPVHLFM 428
           P L++++ L+ +SHD+D +V+Y SIFAMG+VG+GTNN            YH K P +LFM
Sbjct: 702 PRLNILDTLSKFSHDADPEVSYYSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFM 761

Query: 429 VLLAQGLCHAGKGTVTLCPAHANRRLLT 512
           V LAQGL H GKGT+TLCP H++R+L++
Sbjct: 762 VRLAQGLTHLGKGTLTLCPYHSDRQLMS 789



 Score = 75.4 bits (177), Expect = 1e-13
 Identities = 36/53 (67%), Positives = 41/53 (77%)
 Frame = +1

Query: 94  QAVATLGVAVIALAAETGAEMCTRIFGQLGRYGEPVVRRAVPLAIALCSVSNP 252
           Q VA LG+A+IA+  E GAEM  R FG L RYGEP +RRAVPLA+AL SVSNP
Sbjct: 650 QGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNP 702


>U12596-1|AAA87705.1|  853|Homo sapiens tumor necrosis factor type 1
           receptor associated protein protein.
          Length = 853

 Score =  103 bits (246), Expect = 5e-22
 Identities = 47/90 (52%), Positives = 65/90 (72%), Gaps = 2/90 (2%)
 Frame = +3

Query: 249 PALSVIEVLNIYSHDSDNDVAYNSIFAMGL--VGAGTNNXXXXXXXXXXXXYHGKSPVHL 422
           P L++++ L+ +SHD+D +V+YNSIFAMG+  VG+GTNN            YH K P +L
Sbjct: 644 PRLNILDTLSKFSHDADPEVSYNSIFAMGMGMVGSGTNNARLAAMLRQLAQYHAKDPNNL 703

Query: 423 FMVLLAQGLCHAGKGTVTLCPAHANRRLLT 512
           FMV LAQGL H GKGT+TLCP H++R+L++
Sbjct: 704 FMVRLAQGLTHLGKGTLTLCPYHSDRQLMS 733



 Score = 75.4 bits (177), Expect = 1e-13
 Identities = 36/53 (67%), Positives = 41/53 (77%)
 Frame = +1

Query: 94  QAVATLGVAVIALAAETGAEMCTRIFGQLGRYGEPVVRRAVPLAIALCSVSNP 252
           Q VA LG+A+IA+  E GAEM  R FG L RYGEP +RRAVPLA+AL SVSNP
Sbjct: 592 QGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNP 644


>AK000917-1|BAA91423.1|  441|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10055 fis, clone HEMBA1001326. ).
          Length = 441

 Score = 33.1 bits (72), Expect = 0.65
 Identities = 18/49 (36%), Positives = 23/49 (46%)
 Frame = -3

Query: 266 DDGECGLDTEHRAMASGTARRTTGSPYLPSCPKMRVHISAPVSAANAMT 120
           D GEC L   HR + SGT      +   PS P+      A  SA++A T
Sbjct: 342 DGGECVLIKTHRLLGSGTTEENKENDLRPSLPQSYAATVARPSASSAST 390


>BC041792-1|AAH41792.1|  562|Homo sapiens AT rich interactive domain
           3B (BRIGHT-like) protein.
          Length = 562

 Score = 32.7 bits (71), Expect = 0.85
 Identities = 17/45 (37%), Positives = 26/45 (57%)
 Frame = -3

Query: 224 ASGTARRTTGSPYLPSCPKMRVHISAPVSAANAMTATPRVATACT 90
           A+ TA    G+P L S PK+R  I    S++   T++PR++ A T
Sbjct: 342 AAATAAAAAGAPALLSPPKIRFPILGLGSSSGTNTSSPRISPATT 386


>AF116846-1|AAD09133.1|  560|Homo sapiens bright and dead ringer
           gene product homologous protein Bdp protein.
          Length = 560

 Score = 32.7 bits (71), Expect = 0.85
 Identities = 17/45 (37%), Positives = 26/45 (57%)
 Frame = -3

Query: 224 ASGTARRTTGSPYLPSCPKMRVHISAPVSAANAMTATPRVATACT 90
           A+ TA    G+P L S PK+R  I    S++   T++PR++ A T
Sbjct: 341 AAATAAAAAGAPALLSPPKIRFPILGLGSSSGTNTSSPRISPATT 385


>AB208830-1|BAD92067.1|  476|Homo sapiens AT rich interactive domain
           3B (BRIGHT- like) protein variant protein.
          Length = 476

 Score = 32.7 bits (71), Expect = 0.85
 Identities = 17/45 (37%), Positives = 26/45 (57%)
 Frame = -3

Query: 224 ASGTARRTTGSPYLPSCPKMRVHISAPVSAANAMTATPRVATACT 90
           A+ TA    G+P L S PK+R  I    S++   T++PR++ A T
Sbjct: 382 AAATAAAAAGAPALLSPPKIRFPILGLGSSSGTNTSSPRISPATT 426


>BC029864-1|AAH29864.1|  340|Homo sapiens hyaluronan and
           proteoglycan link protein 2 protein.
          Length = 340

 Score = 31.9 bits (69), Expect = 1.5
 Identities = 16/39 (41%), Positives = 20/39 (51%)
 Frame = -2

Query: 243 HRAQGDGERHGAPHYRLPVPTKLSEDAGAHFGARFSCQC 127
           H+AQGD   H  PHY LP    + E   +H GA  +  C
Sbjct: 22  HKAQGDPASHPGPHYLLP---PIHEVIHSHRGATATLPC 57


>AL365181-11|CAI13055.1|  340|Homo sapiens hyaluronan and
           proteoglycan link protein 2 protein.
          Length = 340

 Score = 31.9 bits (69), Expect = 1.5
 Identities = 16/39 (41%), Positives = 20/39 (51%)
 Frame = -2

Query: 243 HRAQGDGERHGAPHYRLPVPTKLSEDAGAHFGARFSCQC 127
           H+AQGD   H  PHY LP    + E   +H GA  +  C
Sbjct: 22  HKAQGDPASHPGPHYLLP---PIHEVIHSHRGATATLPC 57


>AL365181-10|CAI13054.1|  185|Homo sapiens hyaluronan and
           proteoglycan link protein 2 protein.
          Length = 185

 Score = 31.9 bits (69), Expect = 1.5
 Identities = 16/39 (41%), Positives = 20/39 (51%)
 Frame = -2

Query: 243 HRAQGDGERHGAPHYRLPVPTKLSEDAGAHFGARFSCQC 127
           H+AQGD   H  PHY LP    + E   +H GA  +  C
Sbjct: 22  HKAQGDPASHPGPHYLLP---PIHEVIHSHRGATATLPC 57


>AB049061-1|BAB17669.1|  340|Homo sapiens brain link protein-1
           protein.
          Length = 340

 Score = 31.9 bits (69), Expect = 1.5
 Identities = 16/39 (41%), Positives = 20/39 (51%)
 Frame = -2

Query: 243 HRAQGDGERHGAPHYRLPVPTKLSEDAGAHFGARFSCQC 127
           H+AQGD   H  PHY LP    + E   +H GA  +  C
Sbjct: 22  HKAQGDPASHPGPHYLLP---PIHEVIHSHRGATATLPC 57


>AB049054-1|BAB17662.1|  340|Homo sapiens brain link protein-1
           protein.
          Length = 340

 Score = 31.9 bits (69), Expect = 1.5
 Identities = 16/39 (41%), Positives = 20/39 (51%)
 Frame = -2

Query: 243 HRAQGDGERHGAPHYRLPVPTKLSEDAGAHFGARFSCQC 127
           H+AQGD   H  PHY LP    + E   +H GA  +  C
Sbjct: 22  HKAQGDPASHPGPHYLLP---PIHEVIHSHRGATATLPC 57


>BC039867-1|AAH39867.1|  446|Homo sapiens WD repeat domain,
           phosphoinositide interacting 1 protein.
          Length = 446

 Score = 30.7 bits (66), Expect = 3.4
 Identities = 17/49 (34%), Positives = 22/49 (44%)
 Frame = -3

Query: 266 DDGECGLDTEHRAMASGTARRTTGSPYLPSCPKMRVHISAPVSAANAMT 120
           D GEC L   H  + SGT      +   PS P+      A  SA++A T
Sbjct: 347 DGGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSAST 395


>AY691424-1|AAV80760.1|  447|Homo sapiens WIPI-1 alpha protein.
          Length = 447

 Score = 30.7 bits (66), Expect = 3.4
 Identities = 17/49 (34%), Positives = 22/49 (44%)
 Frame = -3

Query: 266 DDGECGLDTEHRAMASGTARRTTGSPYLPSCPKMRVHISAPVSAANAMT 120
           D GEC L   H  + SGT      +   PS P+      A  SA++A T
Sbjct: 348 DGGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSAST 396


>AL136089-7|CAI20013.1|  448|Homo sapiens molybdenum cofactor
           synthesis 1 protein.
          Length = 448

 Score = 29.5 bits (63), Expect = 8.0
 Identities = 12/30 (40%), Positives = 16/30 (53%)
 Frame = -3

Query: 260 GECGLDTEHRAMASGTARRTTGSPYLPSCP 171
           G CG +  HRA   G +R   G+  L +CP
Sbjct: 337 GRCGQEARHRAGGCGFSRGPPGTGSLQACP 366


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 66,754,580
Number of Sequences: 237096
Number of extensions: 1256062
Number of successful extensions: 3472
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 3295
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3471
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5308067764
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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