Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= ovS327C06f
(521 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC018728-1|AAH18728.1| 401|Homo sapiens EIF2B3 protein protein. 120 3e-27
AL136380-7|CAI23133.1| 197|Homo sapiens eukaryotic translation ... 120 3e-27
AL136380-6|CAI23132.1| 412|Homo sapiens eukaryotic translation ... 120 3e-27
AL136380-5|CAI23131.1| 452|Homo sapiens eukaryotic translation ... 120 3e-27
AK024006-1|BAB14770.1| 452|Homo sapiens NA. protein. 120 3e-27
AF257077-1|AAF91351.1| 452|Homo sapiens eukaryotic translation ... 120 3e-27
BC013590-1|AAH13590.1| 721|Homo sapiens eukaryotic translation ... 38 0.021
AK091646-1|BAC03712.1| 721|Homo sapiens protein ( Homo sapiens ... 38 0.021
X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer compl... 33 0.61
BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein comple... 33 0.61
U23028-1|AAC50646.1| 641|Homo sapiens eIF-2Bepsilon protein. 30 4.3
BC051323-1|AAH51323.1| 340|Homo sapiens zinc finger protein 488... 29 7.5
BC026895-1|AAH26895.1| 233|Homo sapiens ZNF488 protein protein. 29 7.5
AL731561-7|CAH74044.1| 340|Homo sapiens zinc finger protein 488... 29 7.5
AK056666-1|BAB71246.1| 340|Homo sapiens protein ( Homo sapiens ... 29 7.5
>BC018728-1|AAH18728.1| 401|Homo sapiens EIF2B3 protein protein.
Length = 401
Score = 120 bits (289), Expect = 3e-27
Identities = 59/123 (47%), Positives = 90/123 (73%)
Frame = +2
Query: 149 LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 328
+EFQ VV+A G GSRM D+ S+ K LLPVG P++WYPLN+LE++GF++V IVV D
Sbjct: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59
Query: 329 SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 508
L A K +K+K +++ IP + D GTA+SL+++ ++ TD+LV+S DLIT++ L++V
Sbjct: 60 QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117
Query: 509 LNL 517
++L
Sbjct: 118 VDL 120
>AL136380-7|CAI23133.1| 197|Homo sapiens eukaryotic translation
initiation factor 2B, subunit 3 gamma, 58kDa protein.
Length = 197
Score = 120 bits (289), Expect = 3e-27
Identities = 59/123 (47%), Positives = 90/123 (73%)
Frame = +2
Query: 149 LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 328
+EFQ VV+A G GSRM D+ S+ K LLPVG P++WYPLN+LE++GF++V IVV D
Sbjct: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59
Query: 329 SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 508
L A K +K+K +++ IP + D GTA+SL+++ ++ TD+LV+S DLIT++ L++V
Sbjct: 60 QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117
Query: 509 LNL 517
++L
Sbjct: 118 VDL 120
>AL136380-6|CAI23132.1| 412|Homo sapiens eukaryotic translation
initiation factor 2B, subunit 3 gamma, 58kDa protein.
Length = 412
Score = 120 bits (289), Expect = 3e-27
Identities = 59/123 (47%), Positives = 90/123 (73%)
Frame = +2
Query: 149 LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 328
+EFQ VV+A G GSRM D+ S+ K LLPVG P++WYPLN+LE++GF++V IVV D
Sbjct: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59
Query: 329 SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 508
L A K +K+K +++ IP + D GTA+SL+++ ++ TD+LV+S DLIT++ L++V
Sbjct: 60 QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117
Query: 509 LNL 517
++L
Sbjct: 118 VDL 120
>AL136380-5|CAI23131.1| 452|Homo sapiens eukaryotic translation
initiation factor 2B, subunit 3 gamma, 58kDa protein.
Length = 452
Score = 120 bits (289), Expect = 3e-27
Identities = 59/123 (47%), Positives = 90/123 (73%)
Frame = +2
Query: 149 LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 328
+EFQ VV+A G GSRM D+ S+ K LLPVG P++WYPLN+LE++GF++V IVV D
Sbjct: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59
Query: 329 SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 508
L A K +K+K +++ IP + D GTA+SL+++ ++ TD+LV+S DLIT++ L++V
Sbjct: 60 QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117
Query: 509 LNL 517
++L
Sbjct: 118 VDL 120
>AK024006-1|BAB14770.1| 452|Homo sapiens NA. protein.
Length = 452
Score = 120 bits (289), Expect = 3e-27
Identities = 59/123 (47%), Positives = 90/123 (73%)
Frame = +2
Query: 149 LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 328
+EFQ VV+A G GSRM D+ S+ K LLPVG P++WYPLN+LE++GF++V IVV D
Sbjct: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59
Query: 329 SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 508
L A K +K+K +++ IP + D GTA+SL+++ ++ TD+LV+S DLIT++ L++V
Sbjct: 60 QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117
Query: 509 LNL 517
++L
Sbjct: 118 VDL 120
>AF257077-1|AAF91351.1| 452|Homo sapiens eukaryotic translation
initiation factor EIF2B subunit 3 protein.
Length = 452
Score = 120 bits (289), Expect = 3e-27
Identities = 59/123 (47%), Positives = 90/123 (73%)
Frame = +2
Query: 149 LEFQVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVLDEDK 328
+EFQ VV+A G GSRM D+ S+ K LLPVG P++WYPLN+LE++GF++V IVV D
Sbjct: 1 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEV-IVVTTRDV 59
Query: 329 SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSARINTDLLVISGDLITNINLNDV 508
L A K +K+K +++ IP + D GTA+SL+++ ++ TD+LV+S DLIT++ L++V
Sbjct: 60 QKALCAEFK--MKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEV 117
Query: 509 LNL 517
++L
Sbjct: 118 VDL 120
>BC013590-1|AAH13590.1| 721|Homo sapiens eukaryotic translation
initiation factor 2B, subunit 5 epsilon, 82kDa protein.
Length = 721
Score = 37.9 bits (84), Expect = 0.021
Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 5/126 (3%)
Frame = +2
Query: 158 QVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVL---DEDK 328
Q V++A R + + LLP+ ++ Y L L G Q+ + + K
Sbjct: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103
Query: 329 SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSAR--INTDLLVISGDLITNINLN 502
++L + P + + +I SE + L+ V A+ + +D L++ GD+I+NIN+
Sbjct: 104 EHLLKSKWCRPTSLNV-VRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINIT 162
Query: 503 DVLNLH 520
L H
Sbjct: 163 RALEEH 168
>AK091646-1|BAC03712.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ34327 fis, clone FEBRA2009022, highly similar to
TRANSLATION INITIATION FACTOR EIF-2B EPSILON SUBUNIT. ).
Length = 721
Score = 37.9 bits (84), Expect = 0.021
Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 5/126 (3%)
Frame = +2
Query: 158 QVVVLAAGKGSRMPDVGGSVSKCLLPVGPYPVLWYPLNMLEKIGFQDVMIVVL---DEDK 328
Q V++A R + + LLP+ ++ Y L L G Q+ + + K
Sbjct: 44 QAVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQIK 103
Query: 329 SNILNALEKCPLKIKYELIVIPSEEDWGTANSLKHVSAR--INTDLLVISGDLITNINLN 502
++L + P + + +I SE + L+ V A+ + +D L++ GD+I+NIN+
Sbjct: 104 EHLLKSKWCRPTSLNV-VRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINIT 162
Query: 503 DVLNLH 520
L H
Sbjct: 163 RALEEH 168
>X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer complex
protein.
Length = 906
Score = 33.1 bits (72), Expect = 0.61
Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 1/119 (0%)
Frame = +2
Query: 56 VNISKIRQTSIYSLFAFQKHHLYLQ*KMHKILEFQVVVLAAGKGSRMPDVGGSVSKCLLP 235
V I+ + +T + + + LYL K I+ + ++V + + S++ +LP
Sbjct: 552 VTIAHLDRTMYLLGYIPKDNRLYLGDKELNIISYSLLVSVLEYQTAVMRRDFSMADKVLP 611
Query: 236 VGPYPVLWYPLNMLEKIGFQDVMIVVLDEDKSNILNALEKCPLKIKYELIV-IPSEEDW 409
P + LEK GF+ + V + + AL+ LKI Y+L V SE+ W
Sbjct: 612 TIPKEQRTRVAHFLEKQGFKQQALTVSTDPEHRFELALQLGELKIAYQLAVEAESEQKW 670
>BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein complex,
subunit beta 2 (beta prime) protein.
Length = 906
Score = 33.1 bits (72), Expect = 0.61
Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 1/119 (0%)
Frame = +2
Query: 56 VNISKIRQTSIYSLFAFQKHHLYLQ*KMHKILEFQVVVLAAGKGSRMPDVGGSVSKCLLP 235
V I+ + +T + + + LYL K I+ + ++V + + S++ +LP
Sbjct: 552 VTIAHLDRTMYLLGYIPKDNRLYLGDKELNIISYSLLVSVLEYQTAVMRRDFSMADKVLP 611
Query: 236 VGPYPVLWYPLNMLEKIGFQDVMIVVLDEDKSNILNALEKCPLKIKYELIV-IPSEEDW 409
P + LEK GF+ + V + + AL+ LKI Y+L V SE+ W
Sbjct: 612 TIPKEQRTRVAHFLEKQGFKQQALTVSTDPEHRFELALQLGELKIAYQLAVEAESEQKW 670
>U23028-1|AAC50646.1| 641|Homo sapiens eIF-2Bepsilon protein.
Length = 641
Score = 30.3 bits (65), Expect = 4.3
Identities = 16/47 (34%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Frame = +2
Query: 386 VIPSEEDWGTANSLKHVSAR--INTDLLVISGDLITNINLNDVLNLH 520
+I SE + L+ V A+ + +D L++ GD+I+NIN+ L H
Sbjct: 42 IITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNINITRALEEH 88
>BC051323-1|AAH51323.1| 340|Homo sapiens zinc finger protein 488
protein.
Length = 340
Score = 29.5 bits (63), Expect = 7.5
Identities = 11/27 (40%), Positives = 18/27 (66%), Gaps = 1/27 (3%)
Frame = +1
Query: 226 SPTCWAV-PSTMVSIKYARKNWISRCN 303
S T WA+ P T+ S+ + +NW ++CN
Sbjct: 255 STTSWALLPPTLTSLGLSTQNWCAKCN 281
>BC026895-1|AAH26895.1| 233|Homo sapiens ZNF488 protein protein.
Length = 233
Score = 29.5 bits (63), Expect = 7.5
Identities = 11/27 (40%), Positives = 18/27 (66%), Gaps = 1/27 (3%)
Frame = +1
Query: 226 SPTCWAV-PSTMVSIKYARKNWISRCN 303
S T WA+ P T+ S+ + +NW ++CN
Sbjct: 148 STTSWALLPPTLTSLGLSTQNWCAKCN 174
>AL731561-7|CAH74044.1| 340|Homo sapiens zinc finger protein 488
protein.
Length = 340
Score = 29.5 bits (63), Expect = 7.5
Identities = 11/27 (40%), Positives = 18/27 (66%), Gaps = 1/27 (3%)
Frame = +1
Query: 226 SPTCWAV-PSTMVSIKYARKNWISRCN 303
S T WA+ P T+ S+ + +NW ++CN
Sbjct: 255 STTSWALLPPTLTSLGLSTQNWCAKCN 281
>AK056666-1|BAB71246.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ32104 fis, clone OCBBF2001307. ).
Length = 340
Score = 29.5 bits (63), Expect = 7.5
Identities = 11/27 (40%), Positives = 18/27 (66%), Gaps = 1/27 (3%)
Frame = +1
Query: 226 SPTCWAV-PSTMVSIKYARKNWISRCN 303
S T WA+ P T+ S+ + +NW ++CN
Sbjct: 255 STTSWALLPPTLTSLGLSTQNWCAKCN 281
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 69,891,463
Number of Sequences: 237096
Number of extensions: 1506535
Number of successful extensions: 2577
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 2500
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2571
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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